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365 results on '"Hiv 1 integrase"'

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1. No difference in HIV-1 integrase inhibitor resistance between CSF and blood compartments

2. HIV-1 Integrase Diversity and Resistance-Associated Mutations and Polymorphisms Among Integrase Strand Transfer Inhibitor-Naive HIV-1 Patients from Cameroon

3. Evaluation of HIV-1 integrase resistance emergence and evolution in patients treated with integrase inhibitors

4. The selenium-containing drug ebselen potently disrupts LEDGF/p75-HIV-1 integrase interaction by targeting LEDGF/p75

6. Emergence of Resistance in HIV-1 Integrase with Dolutegravir Treatment in a Pediatric Population from the IMPAACT P1093 Study

7. Docking, Synthesis and Biological Evaluation of Novel Diketoquinoline Analogues as HIV-1 Integrase Inhibitor

8. Strain-specific effect on biphasic DNA binding by HIV-1 integrase

9. The design of potent HIV-1 integrase inhibitors by a combined approach of structure-based virtual screening and molecular dynamics simulation

10. Evaluation of novelN′-(3-hydroxybenzoyl)-2-oxo-2H-chromene-3-carbohydrazide derivatives as potential HIV-1 integrase inhibitors

11. HIV-1 Integrase Inhibitors with Modifications That Affect Their Potencies against Drug Resistant Integrase Mutants

12. Regression QSAR Models for Predicting HIV-1 Integrase Inhibitors

13. LEDGINs, Inhibitors of the Interaction Between HIV-1 Integrase and LEDGF/p75, Are Potent Antivirals with a Potential to Cure HIV Infection

14. Biological activity and synthesis of 5,6-dihydroxyindole-2-carboxylic acid - biosynthetic precursor of melanins (microreview)

15. Recent Advances in Small-Molecule HIV-1 Integrase Inhibitors

16. Design, synthesis and SAR study of novel C2-pyrazolopyrimidine amides and amide isosteres as allosteric integrase inhibitors

17. Genetic Features of HIV-1 Integrase Sub-Subtype A6 Predominant in Russia and Predicted Susceptibility to INSTIs

18. Design, synthesis and SAR study of bridged tricyclic pyrimidinone carboxamides as HIV-1 integrase inhibitors

19. The determination of CHARMM force field parameters for the Mg2+ containing HIV-1 integrase

20. Synthesis and Evaluation of Aryl Quinolines as HIV-1 Integrase Multimerization Inhibitors

22. Two new tetracyclic triterpenoids from the endophytic fungus Hypoxylon sp. 6269

23. Synthesis and evaluation of substituted 4-arylimino-3-hydroxybutanoic acids as potential HIV-1 integrase inhibitors

24. Prediction of the binding mode and resistance profile for a dual-target pyrrolyl diketo acid scaffold against HIV-1 integrase and reverse-transcriptase-associated ribonuclease H

25. Study of Pyrimidine-4-carboxamide Derivatives as HIV-1 Integrase Inhibitors Using QSAR and DFT Calculations

26. Advances in the development of HIV integrase strand transfer inhibitors

28. Application of the Morita-Baylis-Hillman reaction in the synthesis of 3-[( N -cycloalkylbenzamido)methyl]-2-quinolones as potential HIV-1 integrase inhibitors

29. In silico virtual screening of potent inhibitor to hamper the interaction between HIV-1 integrase and LEDGF/p75 interaction using E-pharmacophore modeling, molecular docking, and dynamics simulations

30. Molecular evolution of HIV-1 integrase during the 20 years prior to the first approval of integrase inhibitors

31. HIV-1 Integrase Inhibitors Resistance: Update of the Current Literature

32. Low Prevalence of HIV-1 Integrase Resistance Among Antiretroviral-Naive Patients Newly Diagnosed with HIV-1 from Belém, Pará, Amazon Region of Brazil

33. Lack of HIV-1 integrase inhibitor resistance among 392 antiretroviral-naïve individuals in a tertiary care hospital in Beijing, China

34. A Ligand-Based Virtual Screening Method Using Direct Quantification of Generalization Ability

35. Author response: HIV-1 integrase tetramers are the antiviral target of pyridine-based allosteric integrase inhibitors

36. Nonhuman Primates and Humanized Mice for Studies of HIV-1 Integrase Inhibitors: A Review

38. Molecular Docking Study of Four Chromene Derivatives as Novel HIV-1 Integrase Inhibitors

39. Quantitative Structure-Activity Relationship and Docking Studies on a Series of Oxadiazole and Triazole Substituted Naphthyridines as HIV-1 Integrase Inhibitors

40. Synthesis of and HIV-1 Integrase Inhibition by 2-[7-(Fluorobenzyloxy)-4-Oxo-4hchromen-3-Yl]-1-Hydroxyimidazoles

41. Allosteric HIV-1 integrase inhibitors promote aberrant protein multimerization by directly mediating inter-subunit interactions: Structural and thermodynamic modeling studies

42. 2-hydroxyisoquinoline-1,3(2 H ,4 H )-diones (HIDs) as human immunodeficiency virus type 1 integrase inhibitors: Influence of the alkylcarboxamide substitution of position 4

43. Rapid activity prediction of HIV-1 integrase inhibitors: harnessing docking energetic components for empirical scoring by chemometric and artificial neural network approaches

44. Application of an R-group search technique into molecular design of HIV-1 integrase inhibitors

45. Chemical Constituents of Incarvillea compacta

46. How HIV-1 Integrase Associates with Human Mitochondrial Lysyl-tRNA Synthetase

48. Synthesis and biological evaluation of bis-N2,N2′-(4-hydroxycoumarin-3-yl)ethylidene]-2,3-dihydroxysuccinodihydrazides

49. HIV-1 Integrase Inhibitors That Are Broadly Effective against Drug-Resistant Mutants

50. Structural Implications of Genotypic Variations in HIV-1 Integrase From Diverse Subtypes

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