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781 results on '"Hofbeck, M."'

3. Laryngeal Ultrasound for Identifying Vocal Fold Motion Impairment after Pediatric Heart Surgery.

Author

Georgiev, Y., Hofbeck, M., Michel, J., Neunhoeffer, F., and Kumpf, M.

Subjects
*VOCAL cords, *PEDIATRIC surgery, *CARDIAC surgery, *ULTRASONIC imaging, *RECURRENT laryngeal nerve, *EXTUBATION, *CARDIOPULMONARY bypass
Abstract

This article discusses the use of laryngeal ultrasound as a non-invasive alternative to laryngoscopy for diagnosing vocal fold motion impairment (VFMI) in pediatric patients after cardiac surgery. VFMI can lead to respiratory and feeding problems, and is commonly seen after procedures involving aortic arch reconstruction. The study conducted a pilot observational study on pediatric patients with upper airway symptoms, and found that laryngeal ultrasound successfully identified VFMI in 3.2% of cases. The authors suggest that laryngeal ultrasound could be used as a screening method for early diagnosis and supportive therapy, but further research is needed to fully evaluate its potential in clinical settings. [Extracted from the article]

Published
2024
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4. Zerebrales Autoregulationsmonitoring auf der Pädiatrischen Intensivstation nach Operation an der Herz-Lungen-Maschine.

Author

Methner, M., Schwaneberg, B., Wikidal, B., Georgiev, Y., Iller, M., Schmid, S., Hofbeck, M., and Neunhoeffer, F.

Subjects
CONFLICT of interests, OXYGEN in the blood
Abstract

This article discusses the importance of monitoring cerebral autoregulation in pediatric patients after heart surgery using a heart-lung machine. The study examined 83 infants and used near-infrared spectroscopy to measure regional cortical oxygen saturation and relative hemoglobin levels, correlating them with invasive arterial mean pressure. The study found that the optimal mean arterial blood pressure for cerebral autoregulation was higher than empirical recommendations. The authors suggest that real-time monitoring of cerebral autoregulation parameters and individualized blood pressure management could optimize cerebral autoregulation and prevent potential complications. [Extracted from the article]

Published
2024
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5. 4D Flow MRI Following TCPC: Comparison of Kinetic Energy in the Ventricles of Patients with Extracardiac Conduit and Lateral Tunnel.

Author

Hanser, A., Hofmeister, M., Martirosian, P., Schick, F., Hofbeck, M., Hornung, A., Kaulitz, R., Krumm, P., Schäfer, J., Nikolaou, K., and Sieverding, L.

Subjects
KINETIC energy, MAGNETIC resonance imaging
Abstract

This article examines the differences in kinetic energy (KE) profiles in the ventricles of patients with univentricular hearts after undergoing total cavopulmonary connection (TCPC) with either an extracardiac conduit (ECFT) or an intraatrial-lateral tunnel (IAFT). The study included 33 patients who underwent 4D-Flow MRI scans, and the results showed that patients with ECFT had lower peak and mean values of KE in late diastole compared to patients with IAFT. Additionally, patients with ECFT were younger and had a shorter follow-up time. The authors suggest that further research is needed to determine if these differences are due to anatomical variations or the time interval after TCPC. [Extracted from the article]

Published
2024
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6. Cardiac Catheter Examination in Kawasaki Disease: Initial Data from the Central European Registry

Author

Weisser, J., additional, Arnold, R., additional, Wolfgang, W., additional, Quandt, D., additional, Riede, F. T., additional, Gräfe, F., additional, Opgen-Rhein, B., additional, Michel, J., additional, Hofbeck, M., additional, Schneider, H., additional, Tanase, D., additional, Tietje, M., additional, Tarusinov, G., additional, Herberg, U., additional, Happel, C., additional, Grohmann, J., additional, Rudolph, A., additional, Arnold, L., additional, Haas, N., additional, and Jakob, A., additional

Published
2023
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8. T2-Weighted MRI following TCPC: Patients with Higher-Grade Changes of Intestinal Lymphatic Vessels Were Younger at SCPC and Have a More Frequent History of Chylothorax

Author

Hanser, A., additional, Hofbeck, M., additional, Hofmeister, M., additional, Hornung, A., additional, Martirosian, P., additional, Esser, M., additional, Schick, F., additional, Kaulitz, R., additional, Michel, J., additional, Nikolaou, K., additional, Schäfer, J., additional, Schlensak, C., additional, and Sieverding, L., additional

Published
2023
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9. COGIA – Clinical course, outcome and genetics of inherited arrhythmias in children: a German multicenter study

Author

Lippert, L., additional, Burkard, T., additional, Markel, F., additional, Debus, V., additional, Stute, F., additional, Kamphues, A., additional, Dalla-Pozza, R., additional, Rupp, S., additional, Gonzalez y Gonzalez, M. B., additional, Junge, C., additional, Kanaan, M., additional, Hoff, K., additional, Hanser, A., additional, Dittmann, S., additional, Westphal, D. S., additional, Clauss, S., additional, Hitz, M. P., additional, Becker, K., additional, Kääb, S., additional, Ewert, P., additional, Hofbeck, M., additional, Wällisch, W., additional, Dittrich, S., additional, Uebing, A., additional, Nürnberg, J. H., additional, Hebe, J., additional, Kozlik-Feldmann, R., additional, Beerbaum, P., additional, Kerst, G., additional, Kehl, H. G., additional, Schulze-Bahr, E., additional, Gebauer, R., additional, Hessling, G., additional, and Wolf, C. M., additional

Published
2023
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10. MAPK AND AKT/MTOR INHIBITION IMPROVES CHILDHOOD RASOPATHY-ASSOCIATED CARDIOMYOPATHY

Author

Andelfinger, G., primary, Zenker, M., additional, Norrish, G., additional, Russell, M., additional, Meisner, J., additional, Peng, D., additional, Prendiville, T., additional, Kleinmahon, J., additional, Kantor, P., additional, Sen, D Gottlieb, additional, Human, D., additional, Ewert, P., additional, Krueger, M., additional, Reber, D., additional, Donner, B., additional, Hart, C., additional, Odri-Komazec, I., additional, Rupp, S., additional, Hahn, A., additional, Hanser, A., additional, Hofbeck, M., additional, Draaisma, J., additional, Udink ten Cate, F., additional, Mussa, A., additional, Ferrero, G., additional, Vaujois, L., additional, Raboisson, M., additional, Delrue, M., additional, Marquis, C., additional, Théorêt, Y., additional, Kaski, J., additional, Gelb, B., additional, and Wolf, C., additional

Published
2022
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20. T2-Weighted MRI following TCPC: Fontan Patients with Type-4 Classification of the Thoracic Lymphatic Channels Show a Lower Exercise Capacity

Author

Hanser, A., additional, Hornung, A., additional, Martirosian, P., additional, Esser, M., additional, Hofmeister, M., additional, Hofbeck, M., additional, Schick, F., additional, Kaulitz, R., additional, Michel, J., additional, Schäfer, J., additional, Nikolaou, K., additional, Schlensak, C., additional, and Sieverding, L., additional

Published
2022
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22. Acquired von Willebrand's Syndrome in Congenital Heart Disease

Author

Icheva, V., additional, Ebert, J., additional, Budde, U., additional, Wiegand, G., additional, Schober, S., additional, Engel, J., additional, Kumpf, M., additional, Jaschonek, K., additional, Neunhoeffer, F., additional, Michel, J., additional, Schlensak, C., additional, Hofbeck, M., additional, and Magunia, H., additional

Published
2022
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23. AKT/mTOR and MAPK Inhibition Improves Childhood RASopathic Cardiomyopathy

Author

Wolf, C. M., additional, Zenker, M., additional, Norrish, G., additional, Russell, M., additional, Meisner, J. K., additional, Peng, D. M., additional, Prendiville, T., additional, Kleinmahon, J., additional, Kantor, P. F., additional, Sen, D. Gottlieb, additional, Human, D. G., additional, Ewert, P., additional, Krueger, M., additional, Reber, D., additional, Donner, B. C., additional, Hart, C., additional, Odri-Komazec, I., additional, Rupp, S., additional, Hahn, A., additional, Hanser, A., additional, Hofbeck, M., additional, Draaisma, J. M., additional, Cate, F.E.A. Udink Ten, additional, Mussa, A., additional, Ferrero, G. B., additional, Marquis, C., additional, Théoret, Y., additional, Kaski, J. P., additional, Gelb, B. D., additional, and Andelfinger, G., additional

Published
2022
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32. Acute and midterm outcomes of the post-approval MELODY Registry: a multicentre registry of transcatheter pulmonary valve implantation

Author

Nordmeyer, J., Ewert, P., Gewillig, M., AlJufan, M., Carminati, M., Kretschmar, O., Uebing, A., Dahnert, I., Rohle, R., Schneider, H., Witsenburg, M., Benson, L., Gitter, R., Bokenkamp, R., Mahadevan, V., Berger, F., Aggoun, Y., Agnoletti, G., Baumgartner, H., Lezo, J.S. de, Sofia, R., Dessy, H., Wolf, D. de, Dittrich, S., Dohlen, G., Emmel, M., Emmertsen, K., Fichtlscherer, S., Gabriel, H., Gaemperli, O., Gamillscheg, A., Godart, F., Guerin, P., Hofbeck, M., Marti, G., Michel-Behnke, I., Milanesi, O., Pinto, F., Qureshi, S., Schranz, D., Sievert, H., Sinisalo, J.P., Sluysmans, T., Spadoni, I., MELODY Registry Investigators, Pediatrics, University of Zurich, and Nordmeyer, Johannes

Subjects
Adult, Male, medicine.medical_specialty, Cardiac Catheterization, Time Factors, Heart disease, Adolescent, Heart Valve Diseases, 610 Medicine & health, 030204 cardiovascular system & hematology, 2705 Cardiology and Cardiovascular Medicine, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Interquartile range, Internal medicine, medicine, Humans, Transcatheter pulmonary valve implantation, 030212 general & internal medicine, Registries, Child, Retrospective Studies, Congenital heart disease, Heart Valve Prosthesis Implantation, Pulmonary Valve, Surrogate endpoint, business.industry, Hazard ratio, RVOT dysfunction, medicine.disease, Confidence interval, medicine.anatomical_structure, Treatment Outcome, Ventricle, 10036 Medical Clinic, Infective endocarditis, Cohort, Cardiology, Female, Cardiology and Cardiovascular Medicine, business, Follow-Up Studies
Abstract

Aims The post-approval MELODY Registry aimed to obtain multicentre registry data after transcatheter pulmonary valve implantation (TPVI) with the Melody™ valve (Medtronic plc.) in a large-scale cohort of patients with congenital heart disease (CHD). Methods and results Retrospective analysis of multicentre registry data after TPVI with the Melody™ valve. Eight hundred and forty-five patients (mean age: 21.0 ± 11.1 years) underwent TPVI in 42 centres between December 2006 and September 2013 and were followed-up for a median of 5.9 years (range: 0–11.0 years). The composite endpoint of TPVI-related events during follow-up (i.e. death, reoperation, or reintervention >48 h after TPVI) showed an incidence rate of 4.2% per person per year [95% confidence interval (CI) 3.7–4.9]. Transcatheter pulmonary valve implantation infective endocarditis (I.E.) showed an incidence rate of 2.3% per person per year (95% CI 1.9–2.8) and resulted in significant morbidity and in nine deaths. In multivariable Cox proportional hazard models, the invasively measured residual right ventricle (RV)-to-pulmonary artery (PA) pressure gradient (per 5 mmHg) was associated with the risk of the composite endpoint (adjusted hazard ratio: 1.21, 95% CI 1.12–1.30; P 2 improved significantly from 36 [interquartile range (IQR) 24–47] to 12 (IQR 7–17) mmHg and 47 to 1%, respectively (P Conclusion The post-approval MELODY Registry confirms the efficacy of TPVI with the Melody™ valve in a large-scale cohort of CHD patients. The residual invasively measured RV-to-PA pressure gradient may serve as a target for further improvement in the composite endpoint and TPVI I.E. However, TPVI I.E. remains a significant concern causing significant morbidity and mortality.

Published
2019

36. Medizinische Leitlinie zur Behandlung von Erwachsenen mit angeborenen Herzfehlern (EMAH): der deutsch-österreichisch-schweizerischen kardiologischen Fachgesellschaften

Author

Schmaltz, A. A., Bauer, U., Baumgartner, H., Cesnjevar, R., de Haan, F., Franke, C., Gabriel, H., Gohlke-Bärwolf, C., Hagl, S., Hess, J., Hofbeck, M., Kaemmerer, H., Kallfelz, H. C., Lange, P. E., Nock, H., Oechslin, E., Schirmer, K. R., Tebbe, U., Trindade, P. Trigo, Weyand, M., and Breithardt, G.

Published
2008
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