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3. Novel Weaving Technology for the Manufacture of 2D Net Shape Fabrics for Cost Effective Textile Reinforced Composites

Author

Vo Duy Minh Phuong, Hoffmann Gerald, and Cherif Chokri

Subjects
2d net shape weaving with firm edge, orw technology, woven fabrics for cost effective composites, Textile bleaching, dyeing, printing, etc., TP890-933
Abstract

Despite significant weight and performance advantages over metal parts, today’s demand for fiber-reinforced polymer composites (FRPC) has been limited mainly by their huge manufacturing cost. The combination of dry textile preforms and low-cost consolidation processes such as resin transfer molding (RTM) has been appointed as a promising approach to low-cost FRPC manufacture. This paper presents an advanced weaving technique developed with the aim to establish a more cost-effective system for the manufacture of dry textile preforms for FRPC. 2D woven fabrics with integrated net shape selvedge can be obtained using the open reed weave (ORW) technology, enabling the manufacture of 2D cut patterns with firm edge, so that oversize cutting and hand trimming after molding are no longer required. The introduction of 2D woven fabrics with net shape selvedge helps to reduce material waste, cycle time and preform manufacturing cost significantly. Furthermore, higher grade of automation in preform fabrication can be achieved.

Published
2018
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6. Supplementary Data from Gene Expression–Based Prediction of Neoadjuvant Chemotherapy Response in Early Breast Cancer: Results of the Prospective Multicenter EXPRESSION Trial

Author

Edlund, Karolina, primary, Madjar, Katrin, primary, Lebrecht, Antje, primary, Aktas, Bahriye, primary, Pilch, Henryk, primary, Hoffmann, Gerald, primary, Hofmann, Manfred, primary, Kolberg, Hans-Christian, primary, Boehm, Daniel, primary, Battista, Marco, primary, Seehase, Martina, primary, Stewen, Kathrin, primary, Gebhard, Susanne, primary, Cadenas, Cristina, primary, Marchan, Rosemarie, primary, Brenner, Walburgis, primary, Hasenburg, Annette, primary, Koelbl, Heinz, primary, Solbach, Christine, primary, Gehrmann, Mathias, primary, Tanner, Berno, primary, Weber, Karsten E., primary, Loibl, Sibylle, primary, Sachinidis, Agapios, primary, Rahnenführer, Jörg, primary, Schmidt, Marcus, primary, and Hengstler, Jan G., primary

Published
2023
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7. Adjuvant Docetaxel in Node-Negative Breast Cancer Patients: A Randomized Trial of AGO-Breast Study Group, German Breast Group, and EORTC-Pathobiology Group

Author

Thomssen, Christoph, primary, Vetter, Martina, additional, Kantelhardt, Eva J., additional, Meisner, Christoph, additional, Schmidt, Marcus, additional, Martin, Pierre M., additional, Clatot, Florian, additional, Augustin, Doris, additional, Hanf, Volker, additional, Paepke, Daniela, additional, Meinerz, Wolfgang, additional, Hoffmann, Gerald, additional, Wiest, Wolfgang, additional, Sweep, Fred C. G. J., additional, Schmitt, Manfred, additional, Jänicke, Fritz, additional, Loibl, Sibylle, additional, Minckwitz, Gunter von, additional, and Harbeck, Nadia, additional

Published
2023
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24. Responsiveness of adjacent ductal carcinoma in situ and changes in HER2 status after neoadjuvant chemotherapy/trastuzumab treatment in early breast cancer—results from the GeparQuattro study (GBG 40)

Author

von Minckwitz, Gunter, Darb-Esfahani, Silvia, Loibl, Sibylle, Huober, Jens, Tesch, Hans, Solbach, Christine, Holms, Frank, Eidtmann, Holger, Dietrich, Klaus, Just, Marianne, Clemens, Michael R., Hanusch, Claus, Schrader, Iris, Henschen, Stephan, Hoffmann, Gerald, Tiemann, Katharina, Diebold, Kurt, Untch, Michael, and Denkert, Carsten

Published
2012
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26. Gene Expression-Based Prediction of Neoadjuvant Chemotherapy Response in Early Breast Cancer: Results of the Prospective Multicenter EXPRESSION Trial

Author

Edlund, Karolina, Madjar, Katrin, Lebrecht, Antje, Aktas, Bahriye, Pilch, Henryk, Hoffmann, Gerald, Hofmann, Manfred, Kolberg, Hans-Christian, Boehm, Daniel, Battista, Marco, Seehase, Martina, Stewen, Kathrin, Gebhard, Susanne, Cadenas, Cristina, Marchan, Rosemarie, Brenner, Walburgis, Hasenburg, Annette, Koelbl, Heinz, Solbach, Christine, Gehrmann, Mathias, Tanner, Berno, Weber, Karsten E., Loibl, Sibylle, Sachinidis, Agapios, Rahnenfuehrer, Joerg, Schmidt, Marcus, Hengstler, Jan G., Edlund, Karolina, Madjar, Katrin, Lebrecht, Antje, Aktas, Bahriye, Pilch, Henryk, Hoffmann, Gerald, Hofmann, Manfred, Kolberg, Hans-Christian, Boehm, Daniel, Battista, Marco, Seehase, Martina, Stewen, Kathrin, Gebhard, Susanne, Cadenas, Cristina, Marchan, Rosemarie, Brenner, Walburgis, Hasenburg, Annette, Koelbl, Heinz, Solbach, Christine, Gehrmann, Mathias, Tanner, Berno, Weber, Karsten E., Loibl, Sibylle, Sachinidis, Agapios, Rahnenfuehrer, Joerg, Schmidt, Marcus, and Hengstler, Jan G.

Abstract

Purpose: Expression-based classifiers to predict pathologic complete response (pCR) after neoadjuvant chemotherapy (NACT) are not routinely used in the clinic. We aimed to build and validate a classifier for pCR after NACT. Patients and Methods: We performed a prospective multicenter study (EXPRESSION) including 114 patients treated with anthracycline/taxane-based NACT. Pretreatment core needle biopsies from 91 patients were used for gene expression analysis and classifier construction, followed by validation in five external cohorts (n = 619). Results: A 20-gene classifier established in the EXPRESSION cohort using a Youden index-based cut-off point predicted pCR in the validation cohorts with an accuracy, AUC, negative predictive value (NPV), positive predictive value, sensitivity, and specificity of 0.811, 0.768, 0.829, 0.587, 0.216, and 0.962, respectively. Alternatively, aiming for a high NPV by defining the cut-off point for classification based on the complete responder with the lowest predicted probability of pCR in the EXPRESSION cohort led to an NPV of 0.960 upon external validation. With this extreme-low cut-off point, a recommendation to not treat with anthracycline/taxane-based NACT would be possible for 121 of 619 unselected patients (19.5%) and 112 of 322 patients with luminal breast cancer (34.8%). The analysis of the molecular subtypes showed that the identification of patients who do not achieve a pCR by the 20-gene classifier was particularly relevant in luminal breast cancer. Conclusions: The novel 20-gene classifier reliably identifies patients who do not achieve a pCR in about one third of luminal breast cancers in both the EXPRESSION and combined validation cohorts.

Published
2021

27. Erratum: Azimuthal anisotropy at the relativistic heavy ion collider: the first and fourth harmonics [Phys. Rev. Lett. 92, 062301 (2004)]

Author

Adams, Joseph R., Adler, Clemens, Aggarwal, Madan Mohan, Ahammed, Zubayer, Amonett, John, Anderson, Bryon D., Anderson, Mike, Arkhipkin, Dmitry A., Averichev, Georgy S., Badyal, S. K., Balewski, Jan, Barannikova, Olga, Barnby, Lee Stuart, Baudot, Jérome, Bekele, Selemon, Belaga, Victoria Vladimirovna, Bellwied, Rene, Berger, Jens, Bezverkhny, B. I., Bhardwaj, S., Bhaskar, P., Bhati, Ashok Kumar, Bichsel, Hans, Billmeier, Anja, Bland, Leslie C., Blyth, Charles O., Bonner, Billy E., Botje, Michiel, Boucham, Abdelkrim, Brandin, Andrei V., Bravar, Alessandro, Cadman, R. V., Cai, Xiang-Zhou, Caines, Helen Louise, Calderón de la Barca Sánchez, Manuel, Carroll, J., Castillo Castellanos, Javier Ernesto, Castro, M., Cebra, Daniel A., Chaloupka, Petr, Chattopadhyay, S., Chen, H. F., Chen, Y., Chernenko, Sergey P., Cherney, Michael Gerard, Chikanian, Alexei, Choi, B., Christie, William, Coffin, Jean Pierre, Cormier, Thomas Michael, Cramer, John G., Crawford, Henry J., Csanád, Máté, Das, Debasish, Das, Supriya, Derevschikov, Anatoly A., Didenko, Lidia, Dietel, Thomas, Dong, W. J., Dong, X., Draper, James E., Du, F., Dubey, Anand Kumar, Dunin, V. B., Dunlop, James C., Dutta Majumdar, Mihir Ranjan, Eckardt, Volker, Efimov, Leonid G., Emelianov, V., Engelage, Jon M., Eppley, Geary Wareham, Erazmus, Barbara Ewa, Estienne, Magali Danielle, Fachini, Patricia, Faine, V., Faivre, Julien, Fatemi, Renee H., Filimonov, Kirill, Filip, Peter, Finch, Evan, Fisyak, Yuri V., Flierl, Dominik Bernhard, Foley, Kenneth John, Fu, J., Gagliardi, Carl A., Gagunashvili, N., Gans, J., Ganti, Murthy S., Gaudichet, L., Germain, Marie, Geurts, Frank, Ghazikhanian, Vahe, Ghosh, Premomoy, Gonzalez, Johan Enmanuel, Grachov, Oleg A., Grigoriev, Vladislav A., Gronstal, S., Grosnick, David P., Guedon, M., Guertin, Steven M., Gupta, Anik, Gushin, E., Gutierrez, Thomas Dominic, Hallman, Timothy J., Hardtke, David H., Harris, John W., Heinz, Mark Thomas, Henry, Thomas W., Heppelmann, Steven Francis, Herston, T., Hippolyte, Boris, Hirsch, Andrew S., Hjort, Eric, Hoffmann, Gerald W., Horsley, M., Huang, Huan Zhong, Huang, Shengli, Humanic, Thomas J., Igo, George J., Ishihara, A., Jacobs, Peter Martin, Jacobs, William W., Janik, Michał, Jiang, H., Johnson, I., Jones, Peter Graham, Judd, Eleanor G., Kabana, Sonia, Kaneta, Kaneta, Kaplan, Morton, Keane, Declan, Khodyrev, V. Yu., Kiryluk, Joanna, Kisiel, Adam Ryszard, Klay, Jennifer Lynn, Klein, Spencer Robert, Klyachko, A., Koetke, Donald D., Kollegger, Thorsten, Kopytine, M., Kotchenda, L., Kovalenko, A. D., Kramer, M., Kravtsov, Peter, Kravtsov, Vladimir I., Krueger, Keith William, Kuhn, Christian Claude, Kulikov, Anatoly I., Kumar, Ajay, Kunde, Gerd J., Kunz, Christopher Lee, Kutuev, R. Kh., Kuznetsov, A. A., Lamont, Matthew A. C., Landgraf, Jeffery M., Lange, S., Lansdell, Curtis Patrick Leon, Lasiuk, Brian, Laue, Frank, Lauret, Jerome, Lebedev, Alexei, Lednický, Richard, LeVine, Micheal J., Li, C., Li, Q., Lindenbaum, Sam J., Lisa, Michael A., Liu, F., Liu, L., Liu, Z., Liu, Q. J., Ljubicic, Tonko A., Llope, William Joseph, Long, H., Longacre, Ronald S., Lopez-Noriega, M., Love, William A., Ludlam, Thomas, Lynn, David, Ma, Jing-guo, Ma, R., Ma, Yu-Gang, Magestro, Daniel, Mahajan, Sanjay, Mangotra, Lalit K., Mahapatra, D. P., Majka, Richard Daniel, Manweiler, Robert W., Margetis, Spyridon, Markert, Christina, Martin, L., Marx, Jay N., Matis, Howard S., Matulenko, Yuri A., McShane, Tom S., Meissner, F., Melnick, Yu., Meščanin, Aleksei P., Messer, Matthias, Miller, M. L., Milosevich, Z., Minaev, Nikolai G., Mironov, Camelia, Mishra, Debadeepti, Mitchell, J., Mohanty, Bedangadas, Molnar, Levente, Moore, C. F., Mora-Corral, M. J., Morozov, Dmitry A., Morozov, V., de Moura, M. M., Munhoz, Marcelo Gameiro, Nandi, Basanta Kumar, Nayak, S. K., Nayak, Tapan Kumar, Nelson, John M., Nevski, P., Niida, Takafumi, Nikitin, Vladimir A., Nogach, Larisa V., Norman, B., Nurušev, Sandibek B., Odyniec, Grazyna Janina, Ogawa, Akio, Okorokov, Vitaly A., Oldenburg, Markus D., Olson, Douglas L., Paic, Guy, Pandey, S. U., Pal, Susanta Kumar, Panebratsev, Yuri, Panitkin, Sergei Yurievich, Pavlinov, A. I., Pawlak, Tomasz Jan, Perevoztchikov, V., Perkins, Chris, Peryt, Wiktor Stanislaw, Petrov, V. A., Phatak, S. C., Picha, R., Planinic, Mirko, Pluta, Jan Marian, Porile, Norbert T., Porter, Jeffrey Brent, Poskanzer, Arthur M., Potekhin, Maxim, Potrebenikova, E., Potukuchi, B. V. K. S., Prindle, Duncan J., Pruneau, Claude A., Putschke, Jörn H., Rai, Gulshan, Rakness, Gregory L., Raniwala, Rashmi, Raniwala, Sudhir, Ravel, Olivier, Ray, Robert L., Razin, Sergej V., Reichhold, Dennis Michael, Reid, Jeffrey G., Renault, G., Retiere, Fabrice, Ridiger, Alexey, Ritter, Hans Georg, Roberts, Jabus B., Rogachevski, O. V., Romero, Juan L., Rose, A., Roy, Christelle Sophie, Ruan, Lijuan, Sahoo, Raghunath, Sakrejda, Iwona, Salur, Sevil, Sandweiss, Jack H., Savin, Igor A., Schambach, Joachim, Scharenberg, Rolf Paul, Schmitz, Norbert, Schroeder, Lee S., Schweda, Kai, Seger, Janet Elizabeth, Seliverstov, D., Seyboth, Peter, Shahaliev, Ehtiram, Shao, M., Sharma, M., Shestermanov, Konstantin E., Shimanskii, S. S., Singaraju, Rama Narayana, Simon, F., Skoro, Goran P., Smirnov, Nikolai, Snellings, Raimond, Sood, Gopika, Sorensen, Paul Richard, Sowinski, James, Spinka, Harold. M., Srivastava, Brijesh Kumar, Stanislaus, S., Stock, Reinhard, Stolpovsky, Alexander, Strichanov, Michail Nikolaevič, Stringfellow, Blair, Struck, Christof, Suaide, Alexandre Alarcon do Passo, Sugarbaker, Evan R., Suire, Christophe Pierre, Šumbera, Michal, Surrow, Bernd, Symons, Timothy James MacNeil, Toledo, Alejandro Szanto de, Szarwas, Piotr, Tai, An, Takahashi, Jun, Tang, Aihong, Thein, Dylan, Thomas, James H., Tikhomirov, V., Todoroki, Takahito, Tokarev, Mikhail V., Tonjes, Marguerite Belt, Trainor, Thomas A., Trentalange, Stephen, Tribble, Robert E., Trivedi, M. D., Trofimov, V., Tsai, Oleg D., Ullrich, Thomas, Underwood, David G., Van Buren, Gene, VanderMolen, A. M., Vasiliev, Alexander Nikolaevich, Vasiliev, M., Vigdor, Steven E., Viyogi, Yogendra P., Voloshin, Sergei, Waggoner, William T., Wang, F., Wang, G., Wang, X. L., Wang, Z. M., Ward, H., Watson, J. W., Wells, R., Westfall, Gary D., Whitten, Charles A., Wieman, Howard, Willson, Robert, Wissink, Scott W., Witt, Richard, Wood, J., Wu, J., Xu, N., Xu, Z., Xu, Z. Z., Yamamoto, E., Yepes, Pablo P., Yurevich, Vladimir Yurevich, Zanevski, Y. V., Zborovský, Imrich, Zhang, Haitao, Zhang, W. M., Zhang, Z. P., Żołnierczuk, Piotr Adam, Zoulkarneev, R., Zoulkarneeva, J., Zubarev, A. N., Adams, Joseph R., Adler, Clemens, Aggarwal, Madan Mohan, Ahammed, Zubayer, Amonett, John, Anderson, Bryon D., Anderson, Mike, Arkhipkin, Dmitry A., Averichev, Georgy S., Badyal, S. K., Balewski, Jan, Barannikova, Olga, Barnby, Lee Stuart, Baudot, Jérome, Bekele, Selemon, Belaga, Victoria Vladimirovna, Bellwied, Rene, Berger, Jens, Bezverkhny, B. I., Bhardwaj, S., Bhaskar, P., Bhati, Ashok Kumar, Bichsel, Hans, Billmeier, Anja, Bland, Leslie C., Blyth, Charles O., Bonner, Billy E., Botje, Michiel, Boucham, Abdelkrim, Brandin, Andrei V., Bravar, Alessandro, Cadman, R. V., Cai, Xiang-Zhou, Caines, Helen Louise, Calderón de la Barca Sánchez, Manuel, Carroll, J., Castillo Castellanos, Javier Ernesto, Castro, M., Cebra, Daniel A., Chaloupka, Petr, Chattopadhyay, S., Chen, H. F., Chen, Y., Chernenko, Sergey P., Cherney, Michael Gerard, Chikanian, Alexei, Choi, B., Christie, William, Coffin, Jean Pierre, Cormier, Thomas Michael, Cramer, John G., Crawford, Henry J., Csanád, Máté, Das, Debasish, Das, Supriya, Derevschikov, Anatoly A., Didenko, Lidia, Dietel, Thomas, Dong, W. J., Dong, X., Draper, James E., Du, F., Dubey, Anand Kumar, Dunin, V. B., Dunlop, James C., Dutta Majumdar, Mihir Ranjan, Eckardt, Volker, Efimov, Leonid G., Emelianov, V., Engelage, Jon M., Eppley, Geary Wareham, Erazmus, Barbara Ewa, Estienne, Magali Danielle, Fachini, Patricia, Faine, V., Faivre, Julien, Fatemi, Renee H., Filimonov, Kirill, Filip, Peter, Finch, Evan, Fisyak, Yuri V., Flierl, Dominik Bernhard, Foley, Kenneth John, Fu, J., Gagliardi, Carl A., Gagunashvili, N., Gans, J., Ganti, Murthy S., Gaudichet, L., Germain, Marie, Geurts, Frank, Ghazikhanian, Vahe, Ghosh, Premomoy, Gonzalez, Johan Enmanuel, Grachov, Oleg A., Grigoriev, Vladislav A., Gronstal, S., Grosnick, David P., Guedon, M., Guertin, Steven M., Gupta, Anik, Gushin, E., Gutierrez, Thomas Dominic, Hallman, Timothy J., Hardtke, David H., Harris, John W., Heinz, Mark Thomas, Henry, Thomas W., Heppelmann, Steven Francis, Herston, T., Hippolyte, Boris, Hirsch, Andrew S., Hjort, Eric, Hoffmann, Gerald W., Horsley, M., Huang, Huan Zhong, Huang, Shengli, Humanic, Thomas J., Igo, George J., Ishihara, A., Jacobs, Peter Martin, Jacobs, William W., Janik, Michał, Jiang, H., Johnson, I., Jones, Peter Graham, Judd, Eleanor G., Kabana, Sonia, Kaneta, Kaneta, Kaplan, Morton, Keane, Declan, Khodyrev, V. Yu., Kiryluk, Joanna, Kisiel, Adam Ryszard, Klay, Jennifer Lynn, Klein, Spencer Robert, Klyachko, A., Koetke, Donald D., Kollegger, Thorsten, Kopytine, M., Kotchenda, L., Kovalenko, A. D., Kramer, M., Kravtsov, Peter, Kravtsov, Vladimir I., Krueger, Keith William, Kuhn, Christian Claude, Kulikov, Anatoly I., Kumar, Ajay, Kunde, Gerd J., Kunz, Christopher Lee, Kutuev, R. Kh., Kuznetsov, A. A., Lamont, Matthew A. C., Landgraf, Jeffery M., Lange, S., Lansdell, Curtis Patrick Leon, Lasiuk, Brian, Laue, Frank, Lauret, Jerome, Lebedev, Alexei, Lednický, Richard, LeVine, Micheal J., Li, C., Li, Q., Lindenbaum, Sam J., Lisa, Michael A., Liu, F., Liu, L., Liu, Z., Liu, Q. J., Ljubicic, Tonko A., Llope, William Joseph, Long, H., Longacre, Ronald S., Lopez-Noriega, M., Love, William A., Ludlam, Thomas, Lynn, David, Ma, Jing-guo, Ma, R., Ma, Yu-Gang, Magestro, Daniel, Mahajan, Sanjay, Mangotra, Lalit K., Mahapatra, D. P., Majka, Richard Daniel, Manweiler, Robert W., Margetis, Spyridon, Markert, Christina, Martin, L., Marx, Jay N., Matis, Howard S., Matulenko, Yuri A., McShane, Tom S., Meissner, F., Melnick, Yu., Meščanin, Aleksei P., Messer, Matthias, Miller, M. L., Milosevich, Z., Minaev, Nikolai G., Mironov, Camelia, Mishra, Debadeepti, Mitchell, J., Mohanty, Bedangadas, Molnar, Levente, Moore, C. F., Mora-Corral, M. J., Morozov, Dmitry A., Morozov, V., de Moura, M. M., Munhoz, Marcelo Gameiro, Nandi, Basanta Kumar, Nayak, S. K., Nayak, Tapan Kumar, Nelson, John M., Nevski, P., Niida, Takafumi, Nikitin, Vladimir A., Nogach, Larisa V., Norman, B., Nurušev, Sandibek B., Odyniec, Grazyna Janina, Ogawa, Akio, Okorokov, Vitaly A., Oldenburg, Markus D., Olson, Douglas L., Paic, Guy, Pandey, S. U., Pal, Susanta Kumar, Panebratsev, Yuri, Panitkin, Sergei Yurievich, Pavlinov, A. I., Pawlak, Tomasz Jan, Perevoztchikov, V., Perkins, Chris, Peryt, Wiktor Stanislaw, Petrov, V. A., Phatak, S. C., Picha, R., Planinic, Mirko, Pluta, Jan Marian, Porile, Norbert T., Porter, Jeffrey Brent, Poskanzer, Arthur M., Potekhin, Maxim, Potrebenikova, E., Potukuchi, B. V. K. S., Prindle, Duncan J., Pruneau, Claude A., Putschke, Jörn H., Rai, Gulshan, Rakness, Gregory L., Raniwala, Rashmi, Raniwala, Sudhir, Ravel, Olivier, Ray, Robert L., Razin, Sergej V., Reichhold, Dennis Michael, Reid, Jeffrey G., Renault, G., Retiere, Fabrice, Ridiger, Alexey, Ritter, Hans Georg, Roberts, Jabus B., Rogachevski, O. V., Romero, Juan L., Rose, A., Roy, Christelle Sophie, Ruan, Lijuan, Sahoo, Raghunath, Sakrejda, Iwona, Salur, Sevil, Sandweiss, Jack H., Savin, Igor A., Schambach, Joachim, Scharenberg, Rolf Paul, Schmitz, Norbert, Schroeder, Lee S., Schweda, Kai, Seger, Janet Elizabeth, Seliverstov, D., Seyboth, Peter, Shahaliev, Ehtiram, Shao, M., Sharma, M., Shestermanov, Konstantin E., Shimanskii, S. S., Singaraju, Rama Narayana, Simon, F., Skoro, Goran P., Smirnov, Nikolai, Snellings, Raimond, Sood, Gopika, Sorensen, Paul Richard, Sowinski, James, Spinka, Harold. M., Srivastava, Brijesh Kumar, Stanislaus, S., Stock, Reinhard, Stolpovsky, Alexander, Strichanov, Michail Nikolaevič, Stringfellow, Blair, Struck, Christof, Suaide, Alexandre Alarcon do Passo, Sugarbaker, Evan R., Suire, Christophe Pierre, Šumbera, Michal, Surrow, Bernd, Symons, Timothy James MacNeil, Toledo, Alejandro Szanto de, Szarwas, Piotr, Tai, An, Takahashi, Jun, Tang, Aihong, Thein, Dylan, Thomas, James H., Tikhomirov, V., Todoroki, Takahito, Tokarev, Mikhail V., Tonjes, Marguerite Belt, Trainor, Thomas A., Trentalange, Stephen, Tribble, Robert E., Trivedi, M. D., Trofimov, V., Tsai, Oleg D., Ullrich, Thomas, Underwood, David G., Van Buren, Gene, VanderMolen, A. M., Vasiliev, Alexander Nikolaevich, Vasiliev, M., Vigdor, Steven E., Viyogi, Yogendra P., Voloshin, Sergei, Waggoner, William T., Wang, F., Wang, G., Wang, X. L., Wang, Z. M., Ward, H., Watson, J. W., Wells, R., Westfall, Gary D., Whitten, Charles A., Wieman, Howard, Willson, Robert, Wissink, Scott W., Witt, Richard, Wood, J., Wu, J., Xu, N., Xu, Z., Xu, Z. Z., Yamamoto, E., Yepes, Pablo P., Yurevich, Vladimir Yurevich, Zanevski, Y. V., Zborovský, Imrich, Zhang, Haitao, Zhang, W. M., Zhang, Z. P., Żołnierczuk, Piotr Adam, Zoulkarneev, R., Zoulkarneeva, J., and Zubarev, A. N.

Published
2021

28. Identified particle elliptic flow in Au+Au collisions at √sNN = 130 GeV

Author

Adler, Clemens, Ahammed, Zubayer, Allgower, Chris, Amonett, John, Anderson, Bryon D., Anderson, Mike, Averichev, Georgy S., Balewski, Jan, Barannikova, Olga, Barnby, Lee Stuart, Baudot, Jérome, Bekele, Selemon, Belaga, Victoria Vladimirovna, Bellwied, Rene, Berger, Jens, Bichsel, Hans, Bland, Leslie C., Blyth, Charles O., Bonner, Billy E., Bossingham, R., Boucham, Abdelkrim, Brandin, Andrei V., Cadman, R. V., Caines, Helen Louise, Calderón de la Barca Sánchez, Manuel, Cardenas, Andrés, Carroll, J., Castillo Castellanos, Javier Ernesto, Castro, M., Cebra, Daniel A., Chattopadhyay, Subhasis, Chen, M. L., Chen, Y., Chernenko, Sergey P., Cherney, Michael Gerard, Chikanian, Alexei, Choi, B., Christie, William, Coffin, Jean Pierre, Conin, Laurent, Cormier, Thomas Michael, Cramer, John G., Crawford, Henry J., DeMello, M., Deng, W. S., Derevschikov, Anatoly A., Didenko, Lidia, Draper, James E., Dunin, V. B., Dunlop, James C., Eckardt, Volker, Efimov, Leonid G., Emelianov, V., Engelage, Jon M., Eppley, Geary Wareham, Erazmus, Barbara Ewa, Fachini, Patricia, Finch, Evan, Fisyak, Yuri V., Flierl, Dominik Bernhard, Foley, K. J., Fu, J., Gagunashvili, N., Gans, J., Gaudichet, L., Germain, Marie, Geurts, Frank, Ghazikhanian, Vahe, Grabski, J., Grachov, Oleg A., Greiner, D., Grigoriev, Vladislav A., Guedon, M., Gushin, E., Hallman, Timothy J., Hardtke, David H., Harris, John W., Heffner, Michael D., Heppelmann, Steven Francis, Herston, T., Hippolyte, Boris, Hirsch, Andrew S., Hjort, Eric, Hoffmann, Gerald W., Horsley, M., Huang, Huan Zhong, Humanic, Thomas J., Hümmler, Holm Gero, Igo, George J., Ishihara, A., Ivanshin, Yu. I., Jacobs, Peter Martin, Jacobs, William W., Janik, Michał, Johnson, I., Jones, Peter Graham, Judd, Eleanor G., Kaneta, Kaneta, Kaplan, Morton, Keane, Declan, Kisiel, Adam Ryszard, Klay, Jennifer Lynn, Klein, Spencer Robert, Klyachko, A., Konstantinov, A. S., Kotchenda, L., Kovalenko, A. D., Kramer, M., Kravtsov, Peter, Krueger, Keith William, Kuhn, Christian Claude, Kulikov, Anatoly I., Kunde, Gerd J., Kunz, Christopher Lee, Kutuev, R. Kh., Kuznetsov, A. A., Lakehal-Ayat, L., Lamas-Valverde, Jose, Lamont, Matthew A. C., Landgraf, Jeffery M., Lange, S., Lansdell, Curtis Patrick Leon, Lasiuk, Brian, Laue, Frank, Lebedev, Alexei, LeCompte, T., Lednický, Richard, Leontiev, V. M., Leszczynski, P., LeVine, Micheal J., Li, Q., Lindenbaum, Sam J., Lisa, Michael A., Ljubicic, Tonko A., Llope, William Joseph, LoCurto, G., Long, H., Longacre, Ronald S., Lopez-Noriega, M., Love, William A., Lynn, David, Majka, Richard Daniel, Maliszewski, A., Margetis, Spyridon, Martin, L., Marx, Jay N., Matis, Howard S., Matulenko, Yuri A., McShane, Tom S., Meissner, F., Melnick, Yu., Meščanin, Aleksei P., Messer, Matthias, Miller, M. L., Milosevich, Z., Minaev, Nikolai G., Mitchell, J., Moiseenko, V. A., Moltz, D., Moore, C. F., Morozov, V., de Moura, M. M., Munhoz, Marcelo Gameiro, Mutchler, G. S., Nelson, John M., Nevski, P., Nikitin, Vladimir A., Nogach, Larisa V., Norman, B., Nurušev, Sandibek B., Odyniec, Grazyna Janina, Ogawa, Akio, Okorokov, Vitaly A., Oldenburg, Markus D., Olson, Douglas L., Paic, Guy, Pandey, S. U., Panebratsev, Yuri, Panitkin, Sergei Yurievich, Pavlinov, A. I., Pawlak, Tomasz Jan, Perevoztchikov, V., Peryt, Wiktor Stanislaw, Petrov, V. A., Pinganaud, W., Platner, E., Pluta, Jan Marian, Porile, Norbert T., Porter, Jeffrey Brent, Poskanzer, Arthur M., Potrebenikova, E., Prindle, Duncan J., Pruneau, Claude A., Radomski, S., Rai, Gulshan, Ravel, Olivier, Ray, Robert L., Razin, Sergej V., Reichhold, Dennis Michael, Reid, Jeffrey G., Retiere, Fabrice, Ridiger, Alexey, Ritter, Hans Georg, Roberts, Jabus B., Rogachevski, O. V., Romero, Juan L., Roy, Christelle Sophie, Russ, D., Rykov, Vladimir L., Sakrejda, Iwona, Sandweiss, Jack H., Saulys, A. C., Savin, Igor A., Schambach, Joachim, Scharenberg, Rolf Paul, Schweda, Kai, Schmitz, Norbert, Schroeder, Lee S., Schüttauf, Andreas, Seger, Janet Elizabeth, Seliverstov, D., Seyboth, Peter, Shahaliev, Ehtiram, Shestermanov, Konstantin E., Shimanskii, S. S., Shvetcov, V. S., Skoro, Goran P., Smirnov, Nikolai, Snellings, Raimond, Sowinski, James, Spinka, Harold. M., Srivastava, Brijesh Kumar, Stephenson, Edward J., Stock, Reinhard, Stolpovsky, Alexander, Strichanov, Michail Nikolaevič, Stringfellow, Blair, Ströbele, Herbert, Struck, Christof, Suaide, Alexandre Alarcon do Passo, Sugarbaker, Evan R., Suire, Christophe Pierre, Šumbera, Michal, Symons, Timothy James MacNeil, Toledo, Alejandro Szanto de, Szarwas, Piotr, Takahashi, Jun, Tang, Aihong, Thomas, James H., Tikhomirov, V., Trainor, Thomas A., Trentalange, Stephen, Tokarev, Mikhail V., Tonjes, Marguerite Belt, Trofimov, V., Tsai, Oleg D., Turner, K., Ullrich, Thomas, Underwood, David G., Van Buren, Gene, VanderMolen, A. M., Vanyashin, A., Vasilevski, I. M., Vasiliev, Alexander Nikolaevich, Vigdor, Steven E., Voloshin, Sergei, Wang, F., Ward, H., Watson, J. W., Wells, R., Wenaus, T., Westfall, Gary D., Whitten, Charles A., Wieman, Howard, Willson, Robert, Wissink, Scott W., Witt, Richard, Xu, N., Xu, Z., Yakutin, A. E., Yamamoto, E., Yang, J., Yepes, Pablo P., Yokosawa, A., Yurevich, Vladimir Yurevich, Zanevski, Y. V., Zborovský, Imrich, Zhang, W. M., Zoulkarneev, R., Zubarev, A. N., Adler, Clemens, Ahammed, Zubayer, Allgower, Chris, Amonett, John, Anderson, Bryon D., Anderson, Mike, Averichev, Georgy S., Balewski, Jan, Barannikova, Olga, Barnby, Lee Stuart, Baudot, Jérome, Bekele, Selemon, Belaga, Victoria Vladimirovna, Bellwied, Rene, Berger, Jens, Bichsel, Hans, Bland, Leslie C., Blyth, Charles O., Bonner, Billy E., Bossingham, R., Boucham, Abdelkrim, Brandin, Andrei V., Cadman, R. V., Caines, Helen Louise, Calderón de la Barca Sánchez, Manuel, Cardenas, Andrés, Carroll, J., Castillo Castellanos, Javier Ernesto, Castro, M., Cebra, Daniel A., Chattopadhyay, Subhasis, Chen, M. L., Chen, Y., Chernenko, Sergey P., Cherney, Michael Gerard, Chikanian, Alexei, Choi, B., Christie, William, Coffin, Jean Pierre, Conin, Laurent, Cormier, Thomas Michael, Cramer, John G., Crawford, Henry J., DeMello, M., Deng, W. S., Derevschikov, Anatoly A., Didenko, Lidia, Draper, James E., Dunin, V. B., Dunlop, James C., Eckardt, Volker, Efimov, Leonid G., Emelianov, V., Engelage, Jon M., Eppley, Geary Wareham, Erazmus, Barbara Ewa, Fachini, Patricia, Finch, Evan, Fisyak, Yuri V., Flierl, Dominik Bernhard, Foley, K. J., Fu, J., Gagunashvili, N., Gans, J., Gaudichet, L., Germain, Marie, Geurts, Frank, Ghazikhanian, Vahe, Grabski, J., Grachov, Oleg A., Greiner, D., Grigoriev, Vladislav A., Guedon, M., Gushin, E., Hallman, Timothy J., Hardtke, David H., Harris, John W., Heffner, Michael D., Heppelmann, Steven Francis, Herston, T., Hippolyte, Boris, Hirsch, Andrew S., Hjort, Eric, Hoffmann, Gerald W., Horsley, M., Huang, Huan Zhong, Humanic, Thomas J., Hümmler, Holm Gero, Igo, George J., Ishihara, A., Ivanshin, Yu. I., Jacobs, Peter Martin, Jacobs, William W., Janik, Michał, Johnson, I., Jones, Peter Graham, Judd, Eleanor G., Kaneta, Kaneta, Kaplan, Morton, Keane, Declan, Kisiel, Adam Ryszard, Klay, Jennifer Lynn, Klein, Spencer Robert, Klyachko, A., Konstantinov, A. S., Kotchenda, L., Kovalenko, A. D., Kramer, M., Kravtsov, Peter, Krueger, Keith William, Kuhn, Christian Claude, Kulikov, Anatoly I., Kunde, Gerd J., Kunz, Christopher Lee, Kutuev, R. Kh., Kuznetsov, A. A., Lakehal-Ayat, L., Lamas-Valverde, Jose, Lamont, Matthew A. C., Landgraf, Jeffery M., Lange, S., Lansdell, Curtis Patrick Leon, Lasiuk, Brian, Laue, Frank, Lebedev, Alexei, LeCompte, T., Lednický, Richard, Leontiev, V. M., Leszczynski, P., LeVine, Micheal J., Li, Q., Lindenbaum, Sam J., Lisa, Michael A., Ljubicic, Tonko A., Llope, William Joseph, LoCurto, G., Long, H., Longacre, Ronald S., Lopez-Noriega, M., Love, William A., Lynn, David, Majka, Richard Daniel, Maliszewski, A., Margetis, Spyridon, Martin, L., Marx, Jay N., Matis, Howard S., Matulenko, Yuri A., McShane, Tom S., Meissner, F., Melnick, Yu., Meščanin, Aleksei P., Messer, Matthias, Miller, M. L., Milosevich, Z., Minaev, Nikolai G., Mitchell, J., Moiseenko, V. A., Moltz, D., Moore, C. F., Morozov, V., de Moura, M. M., Munhoz, Marcelo Gameiro, Mutchler, G. S., Nelson, John M., Nevski, P., Nikitin, Vladimir A., Nogach, Larisa V., Norman, B., Nurušev, Sandibek B., Odyniec, Grazyna Janina, Ogawa, Akio, Okorokov, Vitaly A., Oldenburg, Markus D., Olson, Douglas L., Paic, Guy, Pandey, S. U., Panebratsev, Yuri, Panitkin, Sergei Yurievich, Pavlinov, A. I., Pawlak, Tomasz Jan, Perevoztchikov, V., Peryt, Wiktor Stanislaw, Petrov, V. A., Pinganaud, W., Platner, E., Pluta, Jan Marian, Porile, Norbert T., Porter, Jeffrey Brent, Poskanzer, Arthur M., Potrebenikova, E., Prindle, Duncan J., Pruneau, Claude A., Radomski, S., Rai, Gulshan, Ravel, Olivier, Ray, Robert L., Razin, Sergej V., Reichhold, Dennis Michael, Reid, Jeffrey G., Retiere, Fabrice, Ridiger, Alexey, Ritter, Hans Georg, Roberts, Jabus B., Rogachevski, O. V., Romero, Juan L., Roy, Christelle Sophie, Russ, D., Rykov, Vladimir L., Sakrejda, Iwona, Sandweiss, Jack H., Saulys, A. C., Savin, Igor A., Schambach, Joachim, Scharenberg, Rolf Paul, Schweda, Kai, Schmitz, Norbert, Schroeder, Lee S., Schüttauf, Andreas, Seger, Janet Elizabeth, Seliverstov, D., Seyboth, Peter, Shahaliev, Ehtiram, Shestermanov, Konstantin E., Shimanskii, S. S., Shvetcov, V. S., Skoro, Goran P., Smirnov, Nikolai, Snellings, Raimond, Sowinski, James, Spinka, Harold. M., Srivastava, Brijesh Kumar, Stephenson, Edward J., Stock, Reinhard, Stolpovsky, Alexander, Strichanov, Michail Nikolaevič, Stringfellow, Blair, Ströbele, Herbert, Struck, Christof, Suaide, Alexandre Alarcon do Passo, Sugarbaker, Evan R., Suire, Christophe Pierre, Šumbera, Michal, Symons, Timothy James MacNeil, Toledo, Alejandro Szanto de, Szarwas, Piotr, Takahashi, Jun, Tang, Aihong, Thomas, James H., Tikhomirov, V., Trainor, Thomas A., Trentalange, Stephen, Tokarev, Mikhail V., Tonjes, Marguerite Belt, Trofimov, V., Tsai, Oleg D., Turner, K., Ullrich, Thomas, Underwood, David G., Van Buren, Gene, VanderMolen, A. M., Vanyashin, A., Vasilevski, I. M., Vasiliev, Alexander Nikolaevich, Vigdor, Steven E., Voloshin, Sergei, Wang, F., Ward, H., Watson, J. W., Wells, R., Wenaus, T., Westfall, Gary D., Whitten, Charles A., Wieman, Howard, Willson, Robert, Wissink, Scott W., Witt, Richard, Xu, N., Xu, Z., Yakutin, A. E., Yamamoto, E., Yang, J., Yepes, Pablo P., Yokosawa, A., Yurevich, Vladimir Yurevich, Zanevski, Y. V., Zborovský, Imrich, Zhang, W. M., Zoulkarneev, R., and Zubarev, A. N.

Abstract

We report first results on elliptic flow of identified particles at midrapidity in Au+Au collisions at sqrt[sNN] = 130 GeV using the STAR TPC at RHIC. The elliptic flow as a function of transverse momentum and centrality differs significantly for particles of different masses. This dependence can be accounted for in hydrodynamic models, indicating that the system created shows a behavior consistent with collective hydrodynamical flow. The fit to the data with a simple model gives information on the temperature and flow velocities at freeze-out.

Published
2021

31. Gene Expression–Based Prediction of Neoadjuvant Chemotherapy Response in Early Breast Cancer: Results of the Prospective Multicenter EXPRESSION Trial

Author

Edlund, Karolina, primary, Madjar, Katrin, additional, Lebrecht, Antje, additional, Aktas, Bahriye, additional, Pilch, Henryk, additional, Hoffmann, Gerald, additional, Hofmann, Manfred, additional, Kolberg, Hans-Christian, additional, Boehm, Daniel, additional, Battista, Marco, additional, Seehase, Martina, additional, Stewen, Kathrin, additional, Gebhard, Susanne, additional, Cadenas, Cristina, additional, Marchan, Rosemarie, additional, Brenner, Walburgis, additional, Hasenburg, Annette, additional, Koelbl, Heinz, additional, Solbach, Christine, additional, Gehrmann, Mathias, additional, Tanner, Berno, additional, Weber, Karsten E., additional, Loibl, Sibylle, additional, Sachinidis, Agapios, additional, Rahnenführer, Jörg, additional, Schmidt, Marcus, additional, and Hengstler, Jan G., additional

Published
2021
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38. Efficacy of psychodynamic short-term psychotherapy for depressed breast cancer patients: study protocol for a randomized controlled trial

Author

Zwerenz Rüdiger, Beutel Manfred E, Imruck Barbara H, Wiltink Jörg, Haselbacher Antje, Ruckes Christian, Schmidberger Heinz, Hoffmann Gerald, Schmidt Marcus, Köhler Uwe, Langanke Dagmar, Kortmann Rolf-Dieter, Kuhnt Susanne, Weißflog Gregor, Barthel Yvette, Leuteritz Katja, and Brähler Elmar

Subjects
Breast cancer, Depression, Short-term psychodynamic psychotherapy, Personality, Helping alliance, Quality of life, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Abstract Background There is a lack of psychotherapeutic trials of treatments of comorbid depression in cancer patients. Our study determines the efficacy of a manualized short-term psychodynamic psychotherapy and predictors of outcome by personality and quality of the therapeutic relationship. Methods/design Eligible breast cancer patients with comorbid depression are assigned to short-term psychodynamic psychotherapy (up to 20 + 5 sessions) or to treatment as usual (augmented by recommendation for counseling center and physician information). We plan to recruit a total of 180 patients (90 per arm) in two centers. Assessments are conducted pretreatment, after 6 (treatment termination) and 12 months (follow-up). The primary outcome measures are reduction of the depression score in the Hospital Anxiety and Depression Scale and remission of depression as assessed by means of the Structured Clinical Interview for DSM IV Disorders by independent, blinded assessors at treatment termination. Secondary outcomes refer to quality of life. Discussion We investigate the efficacy of short-term psychodynamic psychotherapy in acute care and we aim to identify predictors for acceptance and success of treatment. Trial registration ISRCTN96793588

Published
2012
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40. Vacuum-assisted breast biopsy: A comparison of 11-gauge and 8-gauge needles in benign breast disease

Author

Kraemer Bernhard, Hoffmann Gerald, Freidel Klaus, Scheler Peter, Okamgba Stella, Hahn Markus, Wallwiener Diethelm, and Krainick-Strobel Ute

Subjects
Surgery, RD1-811, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Abstract Background Minimal invasive breast biopsy is standard care for the diagnosis of suspicious breast lesions. There are different vacuum biopsy (VB) systems in use. The aim of the study was to determine the differences between the 8-gauge and the 11-gauge needle with respect to a) diagnostic reliability, b) complication rate and c) subjective perception of pain when used for vacuum-assisted breast biopsy. Methods Between 01/2000 and 09/2004, 923 patients at St. Josefs-Hospital Wiesbaden underwent VB using the Mammotome® (Ethicon Endosurgery, Hamburg). Depending on preoperative detection, the procedure was performed under sonographic or mammographic guidance under local anaesthesia. All patients included in the study were followed up both clinically and using imaging techniques one week after the VB and a second time after a median of 41 months. Excisional biopsy on the ipsilateral breast was an exclusion criteria. Subjective pain scores were recorded on a scale of 0 – 10 (0 = no pain, 10 = unbearable pain). The mean age of the patients was 53 years (30 – 88). Results 123 patients were included in the study in total. 48 patients were biopsied with the 8-gauge needle and 75 with the 11-gauge needle. The use of the 8-gauge needle did not show any significant differences to the 11-gauge needle with regard to diagnostic reliability, complication rate and subjective perception of pain. Conclusion Our data show that there are no relevant differences between the 8-gauge and 11-gauge needle when used for VB. Under sonographic guidance, the use of the 8-gauge needle is recommended for firm breast tissue due to its sharp scalpel point and especially for complete removal of benign lesions. We did not find any advantages in the use of the larger 8-gauge needle compared to the 11-gauge needle in the mammography setting. The utilisation costs of the 8-gauge needle are somewhat higher.

Published
2008
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42. Joule heating of dry textiles made of recycled carbon fibers and PA6 for the series production of thermoplastic composites.

Author

Reese, Julian, Vorhof, Michael, Hoffmann, Gerald, Böhme, Kurt, and Cherif, Chokri

Abstract

Processing carbon fiber reinforced thermoplastic parts includes heating to form the thermoplastic matrix. The needed heat can be applied externally or internally to the preform. One possibility to generate intrinsic heat involves the use of carbon fibers as a resistive element to induce joule heat. So far, most research efforts have been based on contacting continuous carbon fibers on both ends to melt the thermoplastic matrix of a pre-impregnated preform. The objective of this project is to use a dry hybrid yarn textile in a one-step process to impregnate and rapidly consolidate the dry textile in less than a minute. The desired molding process is based on joule heating of carbon fibers due to an applied current in the transverse fiber direction. This article focuses on the detection of the involved macroscopic parameters. The first composites produced by means of this new method exhibit a high potential with heating times of 15 s, a void fraction below 1%, and flexural properties comparable to the state of the art. [ABSTRACT FROM AUTHOR]

Published
2021
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43. New method for warp yarn arrangement and algorithm for pattern conversion for three-dimensional woven multilayered fabrics.

Author

Vorhof, Michael, Weise, Daniel, Sennewald, Cornelia, and Hoffmann, Gerald

Subjects
YARN, THREE-dimensional textiles, WEAVING, TEXTILES, INTERMEDIATE goods, TECHNICAL textiles
Abstract

Three-dimensional fabrics have an enormous potential for the manufacturing of semi-finished products in a direct preforming procedure for fiber-reinforced materials. The production of these three-dimensional fabrics involves the processing of coarse reinforcing yarns with high warp density. However, conventional weaving looms have not been designed for such applications, and their maximal achievable warp yarn density is therefore severely limited. Friction and clamping between warp yarns impede the shedding process, and fragments of damaged or fibrillated fibers interfere with the weaving process. Most of the solutions for these issues, which has been presented so far, are based on noncommercial technologies or require extensive modification on standard weaving machines. Hence this paper proposes a new shedding method based on double flat steel heddles, which is suitable for the use in conventional weaving looms. The paper gives a detailed description of the new shedding method including the required materials and the technological framework. Furthermore, a suitable algorithm for the fast pattern conversion under consideration of the special technological framework and requirements of the shedding is presented. [ABSTRACT FROM AUTHOR]

Published
2020
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47. Development of spatially branched woven node structures on the conventional weaving loom

Author

Fazeli, Monireh, Hübner, Matthias, Lehmann, Theo, Gebhardt, Ulrike, Hoffmann, Gerald, Cherif, Chokri, Fazeli, Monireh, Hübner, Matthias, Lehmann, Theo, Gebhardt, Ulrike, Hoffmann, Gerald, and Cherif, Chokri

Abstract

The increasing need of consistent implementation of lightweight constructions in many technical fields makes the manufacture of near net-shaped node structure to be used in textile-reinforced composites a subject of great interest. The manufacture of the node structure is required to provide a strong node point whilst maintaining the circumference of each adjoining strut. Despite a variety of available methods to produce three-dimensional nodal fabric, the required geometry for the complex nodular connection element has not yet been fully achieved. Furthermore, the available methods have limitations. The developed woven concept in this work allows for maintaining the configuration of the node structure and dimensions of the tubes, especially at the node points. As a result, all tubes positioned at node points are fully open; this is accomplished without distorting the surrounding area once the flat woven node structure is removed from the loom and erected into three-dimensional configuration. In order to produce a three-dimensional structure on a conventional weaving machine, the structure must be flattened in an appropriate way. By using a mathematical algorithm, it is possible to graph the flattened structure precisely. The developed weaving concept and relating calculation are applied to create the weaving plan of the spatial nodal structures, which can be produced on a shuttle weaving loom. The developed concept in this paper will provide repeatable manufacturing of complex node structures by using the conventional weaving loom. The struts of node structures manufactured using this method can be woven at any angle and with spatial arrangements.

Published
2018

48. Factors affecting the mechanical and geometrical properties of electrostatically flocked pure chitosan fiber scaffolds

Author

Tonndorf, Robert, Gossla, Elke, Kocaman, Recep Türkay, Kirsten, Martin, Hund, Rolf-Dieter, Hoffmann, Gerald, Aibibu, Dilbar, Gelinsky, Michael, Cherif, Chokri, Tonndorf, Robert, Gossla, Elke, Kocaman, Recep Türkay, Kirsten, Martin, Hund, Rolf-Dieter, Hoffmann, Gerald, Aibibu, Dilbar, Gelinsky, Michael, and Cherif, Chokri

Abstract

The field of articular cartilage tissue engineering has developed rapidly, and chitosan has become a promising material for scaffold fabrication. For this paper, wet-spun biocompatible chitosan filament yarns were converted into short flock fibers and subsequently electrostatically flocked onto a chitosan substrate, resulting in a pure, highly open, porous, and biodegradable chitosan scaffold. Analyzing the wet-spinning of chitosan revealed its advantages and disadvantages with respect to the fabrication of the fiber-based chitosan scaffolds. The scaffolds were prepared using varying processing parameters and were analyzed in regards to their geometrical and mechanical properties. It was found that the pore sizes were adjustable between 65 and 310 µm, and the compressive strength was in the range 13–57 kPa.

Published
2018

50. Anastrozole versus tamoxifen for the prevention of locoregional and contralateral breast cancer in postmenopausal women with locally excised ductal carcinoma in situ (IBIS-II DCIS): A double-blind, randomised controlled trial

Author

Forbes, John F, Sestak, Ivana, Howell, Anthony, Bonanni, Bernardo, Bundred, Nigel, Levy, Christelle, von Minckwitz, Gunter, Eiermann, Wolfgang, Neven, Patrick, Stierer, Michael, Holcombe, Chris, Coleman, Robert E, Jones, Louise, Ellis, Ian, Cuzick, Jack, Sainsbury, Richard, Garber, Judy, Warwick, Jane, Buchanan, Mary, Buser, Katharina, Cawthorn, Simon, Coleman, Robert, Dowsett, Mitch, Eastell, Richard, Ejlertsen, Bent, Forbes, John, Kahan, Zsuzsanna, Baclesse, François, Mansel, Robert, Palva, Tiina, Rydén, Lisa, Stuart, Mary, Vaz, Fatima, Marsiglia, Hugo, Benyoucef, Ahmed, Berton-Rigaud, Dominique, Loustalot, Catherine, Serin, Daniel, Kerbrat, Pierre, Eymard, Jean-Christophe, Giard-Lefevre, Sylvia, Bonichon-Lamichhane, Nathalie, Monnier, Alain, Tubiana-Mathieu, Nicole, Piot, Gilles, de Lara, Christine Tunon, Bernard, Olivier, Simon-Swirski, Hélène, Gladieff, Laurence, Regaud, I Claudius, Fouchet-Goudier, Marie-Joseph, Dohollou, Nadine, Aquitaine, Nord, Elgard-Maitre, Anne-Marie, Bergerat, Jean-Pierre, Petit, Thierry, Marti, Adina, Toussaint, Caroline, Del Piano, Francesco, Ibrahim, Mahmoud, Fric, Danièle, Hönig, Arnd, Müller, Volkmar, Marmé, Frederik, Rautenberg, Beate, Schmidt, Marcus, Hanusch, Claus, Paepke, Stefan, Kaltenecker, Gabriele, Lemster, Sabine, Tio, Joke, Reimer, Toralf, Schnappauf, Benjamin, Baumann, Klaus, Schrader, Iris, Mundhenke, Christoph, Liedtke, Cornelia, Meinerz, Wolfgang, Thomssen, Christoph, Christl, Klaus, Hitschold, Thomas, Goerke, Kay, Kast, Karin, Runnebaum, Ingo, Lindner, Christoph, Scheidel, Peter, Herwig, Uwe, Bangemann, Nikola, Sommer, Harald, Göhring, Kornelia, Tulusan, Augustinus, Stauß, Eva, Köhler, Günter, Zahm, Dirk, Augustin, Doris, Hocke, Andrea, Neunhöffer, Tanja, Schmatloch, Sabine, Heinrich, Georg, Groß, Sabine, Breitbach, G P, Scharl, Anton, Klare, Peter, Stefek, Andrea, Hoffmann, Gerald, Martignoni, Franca, Weiss, Erich, Emons, Günter, Tesch, Hans-Christian, Beckmann, Matthias, Schmutzler, Rita, Schütte, Martin, Aktas, Bahriye, Hille-Betz, Ursula, Deryal, Mustafa, Dan Costa, Serban, Blümel, Beate, Göhring, Uwe-Jochen, Kleine-Tebbe, Anke, Schumacher, Claudia, Jasmin, Pourfard, Christoph, Uleer, Kullmer, Uwe, Krabisch, Petra, Gätje, Regine, Schwenzer, Thomas, Hindenburg, Hans-Joachim, Rempen, Andreas, Höffkes, Heinz-Gert, Stickeler, Elmar, Reffert, Christian, Seitz, Stephan, Splitt, Gerd, Böhne, Petra, Gnauert, Karsten, Strittmatter, Hans-Joachim, Baake, Gerold, Rezai, Mahdi, Noesselt, Thomas, Köhne, C-H, Hanf, Volker, Strumberg, Dirk, Dall, Peter, Schleicher, Peter, Schleicher, Bernd, Beldermann, Frank, Berghorn, Michael, Baerens, Dirk-Thoralf, Kolberg, Hans-Christian, Bauer, Lelia, Brucker, Cosima, Steck, Thomas, Boyle, Frances, Chaudhuri, Anupam, Wagga, Wagga, Moylan, Eugene, Donovan, Jenny, Della-Fiorentina, Stephen, Abdi, Ehtesham, Marx, Gavin, Beadle, Geoffrey, Donovan, Michael, Bennett, Ian, Gill, Peter Grantley, Baker, Caroline, Masters, Richard, Blum, Robert, Collins, John, Law, Michael, Hart, Stewart, Kannourakis, George, Snyder, Raymond, Joseph, David, McCrystal, Michael, Campbell, Ian, Jakesz, Raimund, Selim, Ursula, Singer, Christian, Heck, Dietmar, Greil, Richard, Ramoni, Angela, Bjelic-Radisic, Vesna, Reichenauer, Arno, Horvath, Wilfried, Thaler, Josef, Fridrik, Michael, Keckstein, Joerg, Jan, Lamote, L'Hermitte, Marc, Roelstrate, Heidi, Dirix, Luc, Bambust, Inneke, Seret, Monique, Liebens, Fabienne, Maerevoet, Maria, D'Hondt, Lionel, Berliere, Martine, Nogaret, Jean-Marie, Simon, Phillipe, O'Hanlon, Deirdre, Redmond, Henry Paul, Hill, Arnold, Evoy, Denis, Kerin, Michael, Gupta, Rajnish, Martin, Michael J, Fritis, Marcela, Schwartz, Ricardo, Yañez, Maria Loreto, Peralta, Octavio, Graiff, Claudio, Artioli, Fabrizio, Generali, Daniele, Orzalesi, Lorenzo, Visini, Marilena, Michiara, Maria, Pavesi, Lorenzo, Ravaioli, Alberto, Porpiglia, Mauro, Puglisi, Fabio, Pinotti, Graziella, Brincat, Stephen, Buser, Katharina S, Rabaglio, Manuela, Rauch, Daniel, 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Subjects
Medicine (all), Medizin, skin and connective tissue diseases
Abstract

Third-generation aromatase inhibitors are more effective than tamoxifen for preventing recurrence in postmenopausal women with hormone-receptor-positive invasive breast cancer. However, it is not known whether anastrozole is more effective than tamoxifen for women with hormone-receptor-positive ductal carcinoma in situ (DCIS). Here, we compare the efficacy of anastrozole with that of tamoxifen in postmenopausal women with hormone-receptor-positive DCIS.In a double-blind, multicentre, randomised placebo-controlled trial, we recruited women who had been diagnosed with locally excised, hormone-receptor-positive DCIS. Eligible women were randomly assigned in a 1:1 ratio by central computer allocation to receive 1 mg oral anastrozole or 20 mg oral tamoxifen every day for 5 years. Randomisation was stratified by major centre or hub and was done in blocks (six, eight, or ten). All trial personnel, participants, and clinicians were masked to treatment allocation and only the trial statistician had access to treatment allocation. The primary endpoint was all recurrence, including recurrent DCIS and new contralateral tumours. All analyses were done on a modified intention-to-treat basis (in all women who were randomised and did not revoke consent for their data to be included) and proportional hazard models were used to compute hazard ratios and corresponding confidence intervals. This trial is registered at the ISRCTN registry, number ISRCTN37546358.Between March 3, 2003, and Feb 8, 2012, we enrolled 2980 postmenopausal women from 236 centres in 14 countries and randomly assigned them to receive anastrozole (1449 analysed) or tamoxifen (1489 analysed). Median follow-up was 7·2 years (IQR 5·6-8·9), and 144 breast cancer recurrences were recorded. We noted no statistically significant difference in overall recurrence (67 recurrences for anastrozole vs 77 for tamoxifen; HR 0·89 [95% CI 0·64-1·23]). The non-inferiority of anastrozole was established (upper 95% CI

Published
2016

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