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2. Mixed reality architecture

Author

Schnädelbach, Holger Martin

Subjects
721.046, The Bartlett School of Graduate Studies
Abstract

This thesis develops and investigates Mixed Reality Architectures (MRA), dynamic shared architectural topologies, which span physical and virtual spaces. A theoretical framework is developed to describe the field of possible architectures. As the result of a first pilot study, this is then extended with the concept of the Mixed Reality Architectural Cell (MRACell). MRACells consist of one physical and one virtual space, linked by a two-way video and audio connection. The video of a real physical space is rendered on an MRACell, which can move within the virtual environment. A projector and screen in the real space renders an image of the virtual environment from the point of view of that MRACell. Inhabitants can move their MRACell in relation to all others within the shared virtual environment, allowing ad hoc as well as planned remote social interaction. In this sense MRACells can be described as novel architectural interfaces extending real physical space, via a shared virtual environment to link to other real spaces. An in-depth study lasting one year and involving six office-based MRACells, used video recordings, the analysis of event logs, diaries and an interview survey. This produced a series of ethnographic vignettes describing social interaction within MRA in detail. The study found that the MRA was effective at supporting remote social interaction between users. Usage patterns appeared to be motivated by awareness and communication or conversely privacy requirements. This usage maintained and strengthened social ties. Social interaction was both visible to others and part of the everyday activities at the respective office spaces. It resulted from the virtual adjacencies introduced by MRA that allowed the ‘spatial’ integration of remote locations. However, the virtual spatial framework making this possible, introduced new topological limitations on the number of concurrent connections that were available. Overall, it was found that the dynamic architectural topology directly affected social interaction, while social interaction itself re-shaped the topology. These findings are of direct relevance to current developments, which aim to use communications media to overcome the spatial dispersion of work groups in modern organizations. Finally, the differences in use that were observed between groups of inhabitants suggest that spatial cognition in Mixed Reality is affected both by the interface technology and by the social practices surrounding it. In response, it is suggested that in order to investigate the new generation of mixed physical and virtual technologies, cognitive science should take into account their affordances as ‘virtual extensions’ to both our bodies and to our environment.

Published
2007

3. Reproductive toxicity following in utero and lactational exposure to a human-relevant phthalate mixture in rats

Author

Curi, Tatiana Zauer, primary, Passoni, Marcella Tapias, additional, Lima Tolouei, Sara Emilia, additional, de Araújo Ramos, Anderson Tadeu, additional, França de Almeira, Samara Christina, additional, Scinskas, Anna Beatriz Abreu Ferraz, additional, Romano, Renata Marino, additional, de Oliveira, Jeane Maria, additional, Spercoski, Katherinne Maria, additional, Carvalho dos Santos, Ariany, additional, Dalsenter, Paulo Roberto, additional, Koch, Holger Martin, additional, and Martino-Andrade, Anderson Joel, additional

Published
2023
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4. CALET Search for electromagnetic counterparts of gravitational waves in O4

Author

Kawakubo, Yuta, primary, L. Cherry, Michael, additional, Sakamoto, Takanori, additional, Adriani, Oscar, additional, Akaike, Yosui, additional, Asano, Katsuaki, additional, Aaoka, Yoichi, additional, Berti, Eugenio, additional, Bigongiari, Gabriele, additional, Binns, Walter Robert, additional, Bongi, Massimo, additional, Brogi, Paolo, additional, Bruno, Alessandro, additional, Cannady, Nicholas Wade, additional, Castellini, Guide, additional, Checchia, Caterina, additional, Cherry, Walter Robert, additional, Collazuol, Gianmaria, additional, de Nolfo, Georgia A., additional, Ebisawa, Ken, additional, Ficklin, Anthony W., additional, Fuke, Hideyuki, additional, Gonzi, Sandro, additional, Guzik, T. Gregory, additional, Hams, Thomas, additional, Hibino, Kinya, additional, Ichimura, Masakatsu, additional, Ioka, Kunihito, additional, Ishizaki, Wataru, additional, Israel, Martin H., additional, Kasahara, Katsumasa, additional, Kataoka, Jun, additional, Kataoka, Ryuho, additional, Katayose, Yusaku, additional, Kato, Chihiro, additional, Kawanaka, Norita, additional, Kobayashi, Kenko, additional, Kohri, Kazunori, additional, Krawczynski, Henric S., additional, Krizmanic, John F., additional, Maestro, Paolo, additional, Marrocchesi, Pier Simone, additional, Messineo, Alberto Maria, additional, Mitchell, Jason W., additional, Miyake, Shoko, additional, Moiseev, Alexander, additional, Mori, Masaki, additional, Mori, Nicola, additional, Motz, Holger Martin, additional, Munakata, Kazuoki, additional, Nakahira, Satoshi, additional, Nishimura, Jun, additional, Okuno, Shoji, additional, Ormes, Jonathan, additional, OZAWA, Shunsuke, additional, Pacini, Lorenzo, additional, Pacini, Paolo, additional, Rauch, Brian Flint, additional, Ricciarini, Ricciarini, additional, Sakai, Kazuhiro, additional, Sasaki, Makoto, additional, Shimizu, Yuki, additional, Shiomi, Atsushi, additional, Spillantini, Piero, additional, Stolzi, Francesco, additional, Sugita, Satoshi, additional, Sulaj, Arta, additional, Takita, Masato, additional, Tamura, Tadahisa, additional, Terasawa, Toshio, additional, Torii, Shoji, additional, Tsunesada, Yoshiki, additional, Uchihori, Yukio, additional, Vannuccini, Elena, additional, Wefel, John P., additional, Yamaoka, Kazutaka, additional, Yanagita, Shohei, additional, Yoshida, Atsumasa, additional, Yoshida, Kenji, additional, and Zober, Wolfgang V, additional

Published
2023
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5. Helium flux and its ratio to proton flux in cosmic rays measured with CALET on the International Space Station

Author

Brogi, Paolo, primary, Adriani, Oscar, additional, Akaike, Yosui, additional, Asano, Katsuaki, additional, Aaoka, Yoichi, additional, Berti, Eugenio, additional, Bigongiari, Gabriele, additional, Binns, Walter Robert, additional, Bongi, Massimo, additional, Bruno, Alessandro, additional, Cannady, Nicholas Wade, additional, Castellini, Guide, additional, Checchia, Caterina, additional, Cherry, Walter Robert, additional, Collazuol, Gianmaria, additional, de Nolfo, Georgia A., additional, Ebisawa, Ken, additional, Ficklin, Anthony W., additional, Fuke, Hideyuki, additional, Gonzi, Sandro, additional, Guzik, T. Gregory, additional, Hams, Thomas, additional, Hibino, Kinya, additional, Ichimura, Masakatsu, additional, Ioka, Kunihito, additional, Ishizaki, Wataru, additional, Israel, Martin H., additional, Kasahara, Katsumasa, additional, Kataoka, Jun, additional, Kataoka, Ryuho, additional, Katayose, Yusaku, additional, Kato, Chihiro, additional, Kawanaka, Norita, additional, Kawakubo, Yuta, additional, Kobayashi, Kenko, additional, Kohri, Kazunori, additional, Krawczynski, Henric S., additional, Krizmanic, John F., additional, Maestro, Paolo, additional, Marrocchesi, Pier Simone, additional, Messineo, Alberto Maria, additional, Mitchell, Jason W., additional, Miyake, Shoko, additional, Moiseev, Alexander, additional, Mori, Masaki, additional, Mori, Nicola, additional, Motz, Holger Martin, additional, Munakata, Kazuoki, additional, Nakahira, Satoshi, additional, Nishimura, Jun, additional, Okuno, Shoji, additional, Ormes, Jonathan, additional, OZAWA, Shunsuke, additional, Pacini, Lorenzo, additional, Pacini, Paolo, additional, Rauch, Brian Flint, additional, Ricciarini, Ricciarini, additional, Sakai, Kazuhiro, additional, Sakamoto, Takanori, additional, Sasaki, Makoto, additional, Shimizu, Yuki, additional, Shiomi, Atsushi, additional, Spillantini, Piero, additional, Stolzi, Francesco, additional, Sugita, Satoshi, additional, Sulaj, Arta, additional, Takita, Masato, additional, Tamura, Tadahisa, additional, Terasawa, Toshio, additional, Torii, Shoji, additional, Tsunesada, Yoshiki, additional, Uchihori, Yukio, additional, Vannuccini, Elena, additional, Wefel, John P., additional, Yamaoka, Kazutaka, additional, Yanagita, Shohei, additional, Yoshida, Atsumasa, additional, Yoshida, Kenji, additional, and Zober, Wolfgang V, additional

Published
2023
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6. Reproductive toxicity following in utero and lactational exposure to a human-relevant phthalate mixture in rats.

Author

Curi, Tatiana Zauer, Passoni, Marcella Tapias, Tolouei, Sara Emilia Lima, Ramos, Anderson Tadeu de Araújo, Almeira, Samara Christina França de, Scinskas, Anna Beatriz Abreu Ferraz, Romano, Renata Marino, Oliveira, Jeane Maria de, Spercoski, Katherinne Maria, Santos, Ariany Carvalho dos, Dalsenter, Paulo Roberto, Koch, Holger Martin, and Martino-Andrade, Anderson Joel

Subjects
GONADS, PHTHALATE esters, GENITALIA, LABORATORY rats, RATS, PRENATAL exposure, GENE expression
Abstract

This rodent (Wistar rats) study examined reproductive effects of in utero /lactational exposure to a mixture of 6 antiandrogenic phthalates (PMix): diisobutyl phthalate, di- n -butyl phthalate, diisopentyl phthalate, butylbenzyl phthalate, di-2-ethylhexyl phthalate, and diisononyl phthalate. The PMix was defined based on exposure data from pregnant women in Brazil. Experimental groups were established by extrapolating the estimated human dose to rats (0.1 mg/kg/day), followed by up to 3 additional doses corresponding to 5, 1000, and 5000 times the starting rat dose: 0 (control), 0.1, 0.5, 100, and 500 mg/kg/day. The fetal experiment assessed gestational exposure effects on fetal gonads, whereas the postnatal experiment evaluated reproductive parameters in males and females after in utero and lactational exposure. Prenatal exposure decreased fetal testicular testosterone production at 0.5 and 500 mg/kg/day. PMix 500 also reduced mRNA expression of steroidogenesis-related genes, upregulated transcript expression of the retinoic acid-degrading enzyme Cyp26b1 , and increased multinucleated gonocytes incidence in fetal testes. Postnatal assessment revealed antiandrogenic effects at the highest dose, including reduced anogenital distance, nipple retention, and decreased weight of reproductive organs. Early puberty onset (preputial separation) was observed at the lowest dose in males. In contrast, females did not show significant changes in fetal and adult endpoints. Overall, the PMix recapitulated early and late male rat phthalate syndrome phenotypes at the highest dose, but also induced some subtle changes at lower doses, which warrant confirmation and mechanistic assessments. Our data support the use of epidemiologically defined mixtures for exposure risk assessments over traditional toxicological approaches. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Mercury analysis in hair: Comparability and quality assessment within the transnational COPHES/DEMOCOPHES project

Author

Esteban, Marta, Schindler, Birgit Karin, Jiménez, José Antonio, Koch, Holger Martin, Angerer, Jürgen, Rosado, Montserrat, Gómez, Silvia, Casteleyn, Ludwine, Kolossa-Gehring, Marike, Becker, Kerstin, Bloemen, Louis, Schoeters, Greet, Hond, Elly Den, Sepai, Ovnair, Exley, Karen, Horvat, Milena, Knudsen, Lisbeth E., Joas, Anke, Joas, Reinhard, Aerts, Dominique, Biot, Pierre, Borošová, Daniela, Davidson, Fred, Dumitrascu, Irina, Fischer, Marc E., Grander, Margaretha, Janasik, Beata, Jones, Kate, Kašparová, Lucie, Larssen, Thorjørn, Naray, Miklos, Nielsen, Flemming, Hohenblum, Philipp, Pinto, Rui, Pirard, Catherine, Plateel, Gregory, Tratnik, Janja Snoj, Wittsiepe, Jürgen, and Castaño, Argelia

Published
2015
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9. The European COPHES/DEMOCOPHES project: Towards transnational comparability and reliability of human biomonitoring results

Author

Schindler, Birgit Karin, Esteban, Marta, Koch, Holger Martin, Castano, Argelia, Koslitz, Stephan, Cañas, Ana, Casteleyn, Ludwine, Kolossa-Gehring, Marike, Schwedler, Gerda, Schoeters, Greet, Hond, Elly Den, Sepai, Ovnair, Exley, Karen, Bloemen, Louis, Horvat, Milena, Knudsen, Lisbeth E., Joas, Anke, Joas, Reinhard, Biot, Pierre, Aerts, Dominique, Lopez, Ana, Huetos, Olga, Katsonouri, Andromachi, Maurer-Chronakis, Katja, Kasparova, Lucie, Vrbík, Karel, Rudnai, Peter, Naray, Miklos, Guignard, Cedric, Fischer, Marc E., Ligocka, Danuta, Janasik, Beata, Reis, M. Fátima, Namorado, Sónia, Pop, Cristian, Dumitrascu, Irina, Halzlova, Katarina, Fabianova, Eleonora, Mazej, Darja, Tratnik, Janja Snoj, Berglund, Marika, Jönsson, Bo, Lehmann, Andrea, Crettaz, Pierre, Frederiksen, Hanne, Nielsen, Flemming, McGrath, Helena, Nesbitt, Ian, De Cremer, Koen, Vanermen, Guido, Koppen, Gudrun, Wilhelm, Michael, Becker, Kerstin, and Angerer, Jürgen

Published
2014
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12. Intrauterine Exposure to Paracetamol and Aniline Impairs Female Reproductive Development by Reducing Follicle Reserves and Fertility

Author

Holm, Jacob Bak, Mazaud-Guittot, Severine, Danneskiold-Samsøe, Niels Banhos, Chalmey, Clementine, Jensen, Benjamin, Nørregård, Mette Marie, Hansen, Cecilie Hurup, Styrishave, Bjarne, Svingen, Terje, Vinggaard, Anne Marie, Koch, Holger Martin, Bowles, Josephine, Koopman, Peter, Jégou, Bernard, Kristiansen, Karsten, and Kristensen, David Møbjerg

Published
2016
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19. N6 Druckverlust und Wärmeübergang in Plattenwärmeübertragern

Author

Markus Nickolay, Holger Martin, and Benjamin Dietrich

Abstract

3 Druckverlust und Warmeubergang . . . . . . . . . . . . . . . . 1688 3.1 Definitionen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1688 3.2 Einfluss von Pragungswinkel und Durchsatz . . . . . . . 1688 3.2.1 Druckverlust . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1689 3.2.2 Warmeund Stoffubergang . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1689 3.3 Kanale aus Platten mit unterschiedlichen Pragungswinkeln . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1691 3.4 Weitere Einflussgrosen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1691

Published
2019
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43. Unexpected, Ubiquitous Exposure in Brazil to Diisopentyl Phthalate, One of the Most Potent Antiandrogenic Phthalates

Author

Koch, Holger Martin, primary, Bertoncello Souza, Michele, additional, Passoni, Marcella Tapias, additional, Pälmke, Claudia, additional, Meyer, Katlyn Barp, additional, Venturelli, Amanda Caroline, additional, Araújo, Giulia, additional, Morais, Rosana Nogueira, additional, Dalsenter, Paulo Roberto, additional, Swan, Shanna Helen, additional, and Martino-Andrade, Anderson Joel, additional

Published
2018
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48. Nusselt's Fundamental Law of Heat Transfer—Revisited

Author

Holger Martin

Subjects
Fluid Flow and Transfer Processes, Convection, Mechanical Engineering, Law, Heat transfer, Fluid mechanics, Principles of grouping, Condensed Matter Physics, Thermal conduction, Logical consequence, Nusselt number, Argumentation theory, Mathematics
Abstract

Almost a hundred years ago, in 1915, Wilhelm Nusselt published a paper entitled “Das Grundgesetz des Warmeuberganges” (The Fundamental Law of Heat Transfer), which is often quoted in modern textbooks in this field of engineering science. Most of these modern textbooks, however, still use the notion of three mechanisms, modes, or kinds of heat transfer. Nusselt demonstrated, in this mentioned paper, that convection is nothing but conduction to a moving fluid. Nusselt's paper, however, usually is not quoted for this logical conclusion from facts already known in the late 19th and early 20th centuries, but for the principle of similarity or dimensional analysis, leading to the well-known dimensionless numbers widely used in fluid mechanics and heat transfer. The reasons for the reluctance of most (but fortunately not all) present-day experts to follow Nusselt in his logical argumentation have a number of mainly historical roots. This paper tries to explain why teaching our students that there are two mechani...

Published
2013
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