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2,190 results on '"Holl, Reinhard"'

3. Motivational interviewing from the paediatricians’ perspective: assessments after a 2-day training for physicians caring for adolescents with chronic medical conditions (CMCs)

Author

Kammering, Hannah, Cruz, Jennifer Antony, Platzbecker, Anna Lena, Reinauer, Christina, Förtsch, Katharina, Krassuski, Lisa, Viermann, Rabea, Domhardt, Matthias, Baumeister, Harald, Staab, Doris, Minden, Kirsten, Mueller-Stierlin, Annabel Sandra, Holl, Reinhard W., Warschburger, Petra, and Meissner, Thomas

Published
2024
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4. Risk perception, well-being, depression and anxiety in children and adolescents with rheumatic diseases during the COVID-19 pandemic - results from the prospective multicenter KICK-COVID study in Germany

Author

Sengler, Claudia, Klotsche, Jens, Pedersen, Malthe Jessen, Niewerth, Martina, Göldel, Julia, Windschall, Daniel, Haas, Johannes-Peter, Dressler, Frank, Trauzeddel, Ralf, Hospach, Anton, Weller-Heinemann, Frank, Lanzinger, Stefanie, Kamrath, Clemens, Holl, Reinhard W., Warschburger, Petra, and Minden, Kirsten

Published
2024
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5. Anxiety and depression symptoms in adolescents and young adults with juvenile idiopathic arthritis: results of an outpatient screening

Author

Milatz, Florian, Klotsche, Jens, Niewerth, Martina, Sengler, Claudia, Windschall, Daniel, Kallinich, Tilmann, Dressler, Frank, Trauzeddel, Ralf, Holl, Reinhard W., Foeldvari, Ivan, Brück, Normi, Temming, Svenja, Hospach, Toni, Warschburger, Petra, Berendes, Rainer, Erbis, Gabriele, Kuemmerle-Deschner, Jasmin B., Weller-Heinemann, Frank, Haas, Johannes-Peter, Müller-Stierlin, Annabel S., Mutter, Agnes, Meissner, Thomas, Baumeister, Harald, and Minden, Kirsten

Published
2024
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10. Diabetes und Straßenverkehr

Author

Ebert, Oliver, Bohn, Barbara, Bertram, Bernd, Buchberger, Barbara, Finck, Hermann, Hoß, Jürgen, Hübner, Peter, Krabbe, Laura, Kulzer, Bernhard, Küstner, Eva, Lachenmayr, Bernhard, Lemmen, Klaus-Dieter, Petry, Friedhelm, Rinnert, Kurt, Salomon, Markus, Schütt, Wolfgang, Holl, Reinhard W., Maxeiner, Stephan, and Wagener, Wolfgang

Published
2024
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17. Empagliflozin is associated with lower cardiovascular risk compared with dipeptidyl peptidase-4 inhibitors in adults with and without cardiovascular disease: EMPagliflozin compaRative effectIveness and SafEty (EMPRISE) study results from Europe and Asia

Author

Vistisen, Dorte, Carstensen, Bendix, Elisabetta, Patorno, Lanzinger, Stefanie, Tan, Elise Chia-Hui, Yabe, Daisuke, Kim, Dae Jung, Sheu, Wayne H.-H., Melzer-Cohen, Cheli, Holl, Reinhard W., Núñez, Júlio, Ha, Kyoung Hwa, Halvorsen, Sigrun, Langslet, Gisle, Karasik, Avraham, Nyström, Thomas, Niskanen, Leo, Guleria, Sonia, Klement, Riho, Carrasco, Marc, Foersch, Johannes, Shay, Christina, Koeneman, Lisette, Hoti, Fabian, Farsani, Soulmaz Fazeli, Khunti, Kamlesh, Zaccardi, Francesco, Subramanian, Anuradhaa, and Nirantharakumar, Krishnarajah

Published
2023
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23. Diabetes und Straßenverkehr

Author

Ebert, Oliver, Bohn, Barbara, Bertram, Bernd, Buchberger, Barbara, Finck, Hermann, Hoß, Jürgen, Hübner, Peter, Krabbe, Laura, Kulzer, Bernhard, Küstner, Eva, Lachenmayr, Bernhard, Lemmen, Klaus-Dieter, Petry, Friedhelm, Rinnert, Kurt, Salomon, Markus, Schütt, Wolfgang, Holl, Reinhard W., Maxeiner, Stephan, and Wagener, Wolfgang

Published
2023
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25. Fasting indices of glucose-insulin-metabolism across life span and prediction of glycemic deterioration in children with obesity from new diagnostic cut-offs

Author

Hammel, Maximiliane Chiara, Stein, Robert, Kratzsch, Jürgen, Vogel, Mandy, Eckert, Alexander J., Triatin, Rima Destya, Colombo, Marco, Meigen, Christof, Baber, Ronny, Stanik, Juraj, Spielau, Ulrike, Stoltze, Anette, Wirkner, Kerstin, Tönjes, Anke, Snieder, Harold, Holl, Reinhard W., Stumvoll, Michael, Blüher, Matthias, Kiess, Wieland, and Körner, Antje

Published
2023
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26. Gene expression signature predicts rate of type 1 diabetes progression

Author

Mathieu, Chantal, Gillard, Pieter, Casteels, Kristina, Overbergh, Lutgart, Dunger, David, Wallace, Chris, Evans, Mark, Thankamony, Ajay, Hendriks, Emile, Bruggraber, Sylvaine, Marcoveccchio, Loredana, Peakman, Mark, Tree, Timothy, Morgan, Noel G., Richardson, Sarah, Todd, John A., Wicker, Linda, Mander, Adrian, Dayan, Colin, Alhadj Ali, Mohammad, Pieber, Thomas, Eizirik, Decio L., Cnop, Myriam, Brunak, Søren, Pociot, Flemming, Johannesen, Jesper, Rossing, Peter, Quigley, Cristina Legido, Mallone, Roberto, Scharfmann, Raphael, Boitard, Christian, Knip, Mikael, Otonkoski, Timo, Veijola, Riitta, Lahesmaa, Riitta, Oresic, Matej, Toppari, Jorma, Danne, Thomas, Ziegler, Anette G., Achenbach, Peter, Rodriguez-Calvo, Teresa, Solimena, Michele, Bonifacio, Ezio E., Speier, Stephan, Holl, Reinhard, Dotta, Francesco, Chiarelli, Francesco, Marchetti, Piero, Bosi, Emanuele, Cianfarani, Stefano, Ciampalini, Paolo, De Beaufort, Carine, Dahl-Jørgensen, Knut, Skrivarhaug, Torild, Joner, Geir, Krogvold, Lars, Jarosz-Chobot, Przemka, Battelino, Tadej, Thorens, Bernard, Gotthardt, Martin, Roep, Bart O., Nikolic, Tanja, Zaldumbide, Arnaud, Lernmark, Ake, Lundgren, Marcus, Costacalde, Guillaume, Strube, Thorsten, Schulte, Anke M., Nitsche, Almut, Vela, Jose, Von Herrath, Matthias, Wesley, Johnna, Napolitano-Rosen, Antonella, Thomas, Melissa, Schloot, Nanette, Goldfine, Allison, Waldron-Lynch, Frank, Kompa, Jill, Vedala, Aruna, Hartmann, Nicole, Nicolas, Gwenaelle, van Rampelbergh, Jean, Bovy, Nicolas, Dutta, Sanjoy, Soderberg, Jeannette, Ahmed, Simi, Martin, Frank, Latres, Esther, Agiostratidou, Gina, Koralova, Anne, Willemsen, Ruben, Smith, Anne, Anand, Binu, Datta, Vipan, Puthi, Vijith, Zac-Varghese, Sagen, Dias, Renuka, Sundaram, Premkumar, Vaidya, Bijay, Patterson, Catherine, Owen, Katharine, Piel, Barbara, Heller, Simon, Randell, Tabitha, Gazis, Tasso, Reismen, Elise Bismuth, Carel, Jean-Claude, Riveline, Jean-Pierre, Gautier, Jean-Francoise, Andreelli, Fabrizion, Travert, Florence, Cosson, Emmanuel, Penfornis, Alfred, Petit, Catherine, Feve, Bruno, Lucidarme, Nadine, Beressi, Jean-Paul, Ajzenman, Catherina, Radu, Alina, Greteau-Hamoumou, Stephanie, Bibal, Cecile, Meissner, Thomas, Heidtmann, Bettina, Toni, Sonia, Rami-Merhar, Birgit, Eeckhout, Bart, Peene, Bernard, Vantongerloo, N., Maes, Toon, Gommers, Leen, Suomi, Tomi, Starskaia, Inna, Kalim, Ubaid Ullah, Rasool, Omid, Jaakkola, Maria K., Grönroos, Toni, Välikangas, Tommi, Brorsson, Caroline, Mazzoni, Gianluca, Overbergh, Lut, Chmura, Piotr, and Elo, Laura L.

Published
2023
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28. Empagliflozin cardiovascular and renal effectiveness and safety compared to dipeptidyl peptidase-4 inhibitors across 11 countries in Europe and Asia: Results from the EMPagliflozin compaRative effectIveness and SafEty (EMPRISE) study

Author

Karasik, Avraham, Lanzinger, Stefanie, Chia-Hui Tan, Elise, Yabe, Daisuke, Kim, Dae Jung, Sheu, Wayne H-H, Melzer-Cohen, Cheli, Holl, Reinhard W., Ha, Kyoung Hwa, Khunti, Kamlesh, Zaccardi, Francesco, Subramanian, Anuradhaa, Nirantharakumar, Krishnarajah, Nyström, Thomas, Niskanen, Leo, Linnemann Jensen, Majken, Hoti, Fabian, Klement, Riho, Déruaz-Luyet, Anouk, Kyaw, Moe H., Koeneman, Lisette, Vistisen, Dorte, Carstensen, Bendix, Halvorsen, Sigrun, Langslet, Gisle, Fazeli Farsani, Soulmaz, Patorno, Elisabetta, and Núñez, Júlio

Published
2023
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31. Impact of the COVID-19 pandemic on long-term trends in the prevalence of diabetic ketoacidosis at diagnosis of paediatric type 1 diabetes: an international multicentre study based on data from 13 national diabetes registries

Author

Birkebaek, Niels H, Kamrath, Clemens, Grimsmann, Julia M, Aakesson, Karin, Cherubini, Valentino, Dovc, Klemen, de Beaufort, Carine, Alonso, Guy T, Gregory, John W, White, Mary, Skrivarhaug, Torild, Sumnik, Zdenek, Jefferies, Craig, Hörtenhuber, Thomas, Haynes, Aveni, De Bock, Martin, Svensson, Jannet, Warner, Justin T, Gani, Osman, Gesuita, Rosaria, Schiaffini, Riccardo, Hanas, Ragnar, Rewers, Arleta, Eckert, Alexander J, Holl, Reinhard W, and Cinek, Ondrej

Published
2022
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32. Risk of cardiovascular events and death associated with initiation of SGLT2 inhibitors compared with DPP-4 inhibitors: an analysis from the CVD-REAL 2 multinational cohort study

Author

Kosiborod, Mikhail, Cavender, Matthew A, Wilding, John P, Khunti, Kamlesh, Norhammar, Anna, Birkeland, Kåre, Jørgensen, Marit Eika, Holl, Reinhard W., Lam, Carolyn SP, Gulseth, Hanne Løvdal, Carstensen, Bendix, Bollow, Esther, Franch-Nadal, Josep, García Rodríguez, Luis Alberto, Karasik, Avraham, Tangri, Navdeep, Kohsaka, Shun, Kim, Dae Jung, Shaw, Jonathan, Arnold, Suzanne, Goh, Su-Yen, Fenici, Peter, Bodegård, Johan, Chen, Hungta, Surmont, Filip, Blak, Betina T., Wittbrodt, Eric T., Saathoff, Matthias, Noguchi, Yusuke, Tan, Donna, Williams, Maro, Lee, Hye Won, Greenbloom, Maya, Kaidanovich-Beilin, Oksana, Yeo, Khung Keong, Bee, Yong Mong, Khoo, Joan, Koong, Agnes, Lau, Yee How, Gao, Fei, Tan, Wee Boon, Kadir, Hanis Abdul, Ha, Kyoung Hwa, Lee, Jinhee, Chodick, Gabriel, Melzer-Cohen, Cheli, Whitlock, Reid, Cea-Soriano, Lucia, Cantero, Oscar Fernándex, Menzin, Jordan A., Guthrie, Matthew, Ilomaki, Jennie, Magliano, Dianna, Lam, Carolyn S P, Jørgensen, Marit E, Birkeland, Kåre I, Holl, Reinhard W, Shaw, Jonathan E, Ilomäki, Jenni, Chiang, Chern-En, Thuresson, Marcus, and Wittbrodt, Eric

Published
2020
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34. Trends in pharmacological management of paediatric patients with type 2 diabetes from 2000 to 2023 in German‐speaking countries: Analysis based on the Diabetes Prospective Follow‐up Registry.

Author

Wiegand, Susanna, Becker, Marianne, Schmid, Stefanie, Weghuber, Daniel, Weihrauch‐Blüher, Susann, Reinehr, Thomas, Oeverink, Rudolf, Kapellen, Thomas Michael, Denzer, Christian, Tauschmann, Martin, Körner, Antje, Holl, Reinhard W., and Prinz, Nicole

Subjects
TYPE 2 diabetes, GLUCAGON-like peptide-1 receptor, DIABETES in children, INSULIN therapy, GLYCEMIC control, CHILDHOOD obesity, OVERWEIGHT children
Abstract

The article analyzes trends in pharmacological management of pediatric patients with type 2 diabetes in German-speaking countries from 2000 to 2023 based on the Diabetes Prospective Follow-up Registry. The study shows changes in treatment regimens over the years, with an increase in the use of oral antidiabetic drugs (OADs) and glucagon-like peptide-1 receptor agonists (GLP1-RAs), and a decrease in insulin monotherapy or lifestyle intervention alone. Despite the availability of new treatment options, significant improvements in metabolic control and body mass index (BMI) are challenging to achieve in real-world settings. The study highlights the need for further research to determine the impact of expanded therapeutic options on pediatric patients with type 2 diabetes. [Extracted from the article]

Published
2024
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35. Clinical characteristics, treatment, and treatment switch after molecular‐genetic classification in individuals with maturity‐onset diabetes of the young: Insights from the multicenter real‐world DPV registry.

Author

Lanzinger, Stefanie, Laubner, Katharina, Warncke, Katharina, Mader, Julia K., Kummer, Sebastian, Boettcher, Claudia, Biester, Torben, Galler, Angela, Klose, Daniela, and Holl, Reinhard W.

Subjects
TYPE 1 diabetes, MATURITY onset diabetes of the young, PANCREATIC beta cells, ORAL medication, INSULIN therapy
Abstract

Background: Individuals with maturity‐onset diabetes of the young (MODY) are often misdiagnosed as type 1 or type 2 diabetes and receive inappropriate care. We aimed to investigate the characteristics and treatment of all MODY types in a multicenter, real‐world setting. Methods: Individuals with MODY from the diabetes prospective follow‐up (DPV) registry were studied. We compared clinical parameters during the first year of diabetes and the most recent treatment year after MODY diagnosis. Results: A total of 1640 individuals were identified with GCK‐MODY (n = 941) and HNF1A‐MODY (n = 417) as the most frequent types. Among these, 912 individuals were available with information during the first and the most recent treatment year (median duration of follow‐up: 4.2 years [2.6–6.6]). Positive beta cell autoantibodies were present in 20.6% (15.2% IAA). Median age at diagnosis ranged from 9.9 years in GCK‐MODY (Q1–Q3: 6.2–13.1 years) and INS‐MODY (2.7–13.7 years) to 14.3 years (5.0–17.1) in KCNJ11‐MODY. Frequency of oral antidiabetic agents (OAD) use increased and insulin decreased in HNF4A‐MODY (OAD: 18% to 39%, insulin: 34% to 23%) and in HNF1A‐MODY (OAD: 18% to 31%, insulin: 35% to 25%). ABCC8‐MODY was characterized by a decrement in nonpharmacological treatment (26% to 16%) and "insulin only" treatment (53% to 42%), while the proportion of individuals treated with OAD but no insulin increased from 0% to 21%. Conclusions: Our results indicate that some teams caring for individuals with MODY are hesitant with regard to current recommendations. Registries are an essential source of information and provide a basis for discussing treatment guidelines for MODY. [ABSTRACT FROM AUTHOR]

Published
2024
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37. Clinical Outcomes in Pediatric Patients With Type 1 Diabetes With Early Versus Late Diagnosis: Analysis From the DPV Registry.

Author

Hammersen, Johanna, Tittel, Sascha R., Kamrath, Clemens, Warncke, Katharina, Galler, Angela, Menzel, Ulrike, Hess, Melanie, Meißner, Thomas, Karges, Beate, and Holl, Reinhard W.

Subjects
CONTINUOUS glucose monitoring, TYPE 1 diabetes, CHILD patients, DELAYED diagnosis, DIABETIC acidosis
Abstract

OBJECTIVE: This study was conducted to evaluate the effects of early clinical diagnosis of type 1 diabetes by comparison of clinical parameters at diagnosis and during follow-up in patients with pediatric type 1 diabetes with early, intermediate, and late diagnosis. RESEARCH DESIGN AND METHODS: In a population-based analysis, data on 14,292 pediatric patients with type 1 diabetes diagnosed between 2015 and 2019 were retrieved from the Diabetes Prospective Documentation (DPV) registry in March 2023. Patients were divided into four groups: one with diabetic ketoacidosis (DKA) at diagnosis and three with early, intermediate, or late diagnosis based on age-dependent HbA1c terciles. Laboratory-measured HbA1c values and those estimated from continuous glucose monitoring were aggregated as a combined glucose indicator (CGI). Insulin dose–adjusted CGI values <9% were defined as partial remission. RESULTS: At diagnosis, patients had a median age of 9.8 years (IQR 6.8; 13.0). Three years later, patients with early diagnosis had lower CGI than patients with late diagnosis or DKA (mean [95% CI] 7.46% [7.40; 7.53] vs. 7.81% [7.75; 7.87] or 7.74% [7.68; 7.79], respectively; each P < 0.001). More patients experienced partial remission (12.6% [11.0; 14.4] vs. 9.1% [7.7; 10.7] or 8.6% [7.3; 10.0]; each P < 0.001), and 11.7% [10.2; 13.5] of patients with intermediate diagnosis were in partial remission. CONCLUSIONS: Early clinical diagnosis of type 1 diabetes may be beneficial for metabolic control and remission after 3 years of follow-up. Patients diagnosed early may represent a distinct group with better resources or with a different disease biology and slower β-cell destruction, which needs further evaluation. [ABSTRACT FROM AUTHOR]

Published
2024
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41. Diabetes und Straßenverkehr

Author

Ebert, Oliver, Bohn, Barbara, Bertram, Bernd, Buchberger, Barbara, Finck, Hermann, Hoß, Jürgen, Hübner, Peter, Krabbe, Laura, Kulzer, Bernhard, Küstner, Eva, Lachenmayr, Bernhard, Lemmen, Klaus-Dieter, Petry, Friedhelm, Rinnert, Kurt, Salomon, Markus, Schütt, Wolfgang, and Holl, Reinhard W.

Published
2022
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43. Diabetes care and outcomes of pediatric refugees and migrants from Ukraine and Syria/Afghanistan with type 1 diabetes in German-speaking countries

Author

Auzanneau, Marie, primary, Reinauer, Christina, additional, Ziegler, Julian, additional, Golembowski, Sven, additional, de Beaufort, Carine, additional, Schöttler, Hannah, additional, Hahn, Eva, additional, Mirza, Joaquina, additional, Galler, Angela, additional, Wurm, Michael, additional, and Holl, Reinhard W., additional

Published
2024
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45. Poorly controlled pediatric type 1 diabetes mellitus is a risk factor for metabolic dysfunction associated steatotic liver disease (MASLD): An observational study

Author

Koutny, Florian, primary, Wiemann, Dagobert, additional, Eckert, Alexander, additional, Meyhöfer, Svenja, additional, Fritsch, Maria, additional, Pappa, Angeliki, additional, Wiegand, Susanna, additional, Weyer, Marc, additional, Wurm, Michael, additional, Weghuber, Daniel, additional, and Holl, Reinhard W., additional

Published
2024
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