86 results on '"Holmes RD"'
Search Results
2. Aspect of the chemistry of bis(heptafluorobutyrato) zirconium (IV) fluoride
- Author
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Holmes, RD, primary, Nash, J, additional, Riley, D, additional, and Sutcliffe, H, additional
- Published
- 1991
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3. A study to assess the validity of clinical judgement in determining paediatric dental anxiety and related outcomes of management.
- Author
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Holmes RD and Girdler NM
- Abstract
OBJECTIVE: The aim of the present study was to determine the validity of subjective anxiety assessment and the outcomes of management of children receiving operative dental treatment. SETTING: The study was conducted at the Departments of Sedation and Child Dental Health, Newcastle Dental Hospital, Newcastle upon Tyne, UK. SUBJECTS AND METHODS: One hundred children and adolescents aged between 8 and 15 years participated in the study. Clinicians subjectively allocated 50 children for treatment with local analgesia alone (low anxiety), and identified 50 children who had the potential to benefit from nitrous oxide and oxygen sedation (high anxiety). Participants then completed the State-Trait Anxiety Inventory for Children (STAIC), the Venham Picture Test (VPT) and the Child Fear Survey Schedule-Dental Subscale (CFSS-DS). A global rating scale classified behaviour during dental treatment. RESULTS: State anxiety and dental fear prior to treatment were significantly higher in children allocated to receive inhalation sedation (P = 0.004 and P = 0.005, respectively). There was no significant difference in trait anxiety or post-treatment state anxiety between the two groups (P = 0.69 and P = 0.06, respectively). Only 11% displayed 'negative' behaviour during treatment: 82% of this group represented those allocated to receive sedation. CONCLUSION: Children receiving inhalation sedation were significantly more anxious prior to treatment than children receiving treatment with local analgesia alone. The findings support the subjective assessment of anxiety in children; however, objective anxiety measures may assist clinicians in identifying specific fears, which may ultimately aid patient management. [ABSTRACT FROM AUTHOR]
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- 2005
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4. Sea Snakes of the Eastern Gulf of Carpentaria
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Redfield, JA, Holmes, JC, and Holmes, RD
- Abstract
Sea snakes from the eastern Gulf of Carpentaria were regularly sampled from April to December 1976. Thirteen species of snakes were represented among the 341 individuals collected. Over 61 % of these were of one species, Lapemis hardwickii, and none of the other 12 species represented more than 10% of the catch. There were several major differences between our sample and earlier studies in the Gulf and none of these differences could be accounted for. We speculate that earlier studies may have been due to biased samples or to real changes in sea snake distribution and abundance patterns caused by fishing.
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- 1978
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5. Reduction of acute anterior shoulder dislocations using the Milch technique: a study of ski injuries
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J A Russell, J H Vargas rd, E M Holmes rd, and D J Keller
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Adult ,Male ,medicine.medical_specialty ,Shoulders ,medicine.medical_treatment ,Anesthesia, General ,Critical Care and Intensive Care Medicine ,Recurrence ,Skiing ,Methods ,Medicine ,Humans ,Reduction (orthopedic surgery) ,Left shoulder ,business.industry ,Muscle Relaxants, Central ,Shoulder Dislocation ,Anterior shoulder ,Surgery ,External rotation ,Orthopedic surgery ,Athletic Injuries ,Female ,Analgesia ,business ,Diazepam ,medicine.drug ,Greater Tuberosity - Abstract
During the 1977-78, 1978-79, and 1979-80 ski seasons, 76 acute anterior shoulder dislocations were treated by one of three Orthopedic Surgeons at the Rutland Vermont Hospital Emergency Room: 68 (89.4%) were reduced on first attempt using the Milch technique of abduction and external rotation. Four (5.2%) required general anesthesia and four were reduced using meperidine hydrochloride (Demerol, Winthrop) and diazepam (Valium, Roche) and a traction-countertraction technique. Of the 68 shoulders reduced with the Milch technique, 47 (69.1%) required no analgesics or muscle relaxants. There were no complications attributable to the technique itself. Males were injured more frequently than females in a 4.4:1 ratio. Left shoulder injuries were as common as right. Recurrent dislocations occurred more frequently in younger individuals. Fractures of the greater tuberosity were associated injuries in five (6.6%) of all dislocations. These all occurred in individuals older than age 39 years and were coincident with primary dislocations.
- Published
- 1981
6. Widened sutures in childhood meningitis: unrecognized sign of an acute illness
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Holmes, RD, primary, Kuhns, LR, additional, and Oliver, WJ, additional
- Published
- 1977
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7. A study to assess the validity of clinical judgement in determining paediatric dental anxiety and related outcomes of management
- Author
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Holmes, RD and Girdler, NM
- Published
- 2006
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8. Barriers to Accessing Primary Dental Care in Adults with Alcohol Dependence: A Qualitative Study.
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Bowes C, Breckons M, Holmes RD, Durham J, and Bareham BK
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- Humans, Male, Female, Adult, Middle Aged, Primary Health Care, Aged, Oral Health, Motivation, England, Qualitative Research, Alcoholism therapy, Health Services Accessibility, Dental Care
- Abstract
Background: People with alcohol dependence (AD) frequently experience oral health problems, but their dental attendance is poor, with limited evidence to the reasons why from their perspective., Objective: To explore perceived barriers, motivators, and facilitators to accessing primary dental care in people with AD., Methods: Qualitative study consisting of remote one-to-one and group semistructured interviews with a convenience sample of adults with lived experience of AD in northern England. Data were audio-recorded, transcribed, and coded. A reflexive thematic analysis method was used; use of COM-B model informed data interpretation., Results: Twenty adults with lived experience of AD participated in 18 one-to-one interviews and 1 group interview (of 3 participants). Barriers to access were fear and physical, social, and environmental factors (physical effects of AD, financial barriers, nonprioritization of oral health). Motivators to access were pain and prioritization of oral health. Facilitators to access were patterns of alcohol use (i.e., sobriety) and dental service provision within recovery services., Conclusions: Fear of "the dentist" is a major barrier to accessing dental care, and pain is the primary motivator, among people with AD, although neither are unique to this population. Fear and physical, social, and environmental barriers to access contribute to problem-oriented attendance, which negatively affect oral health outcomes. Opportunity to facilitate attendance increases when a person is in remission from AD through their physical capabilities improving. Increasing capability and opportunity can influence attendance beyond the automatic motivation of pain. Provision of dental care within recovery services could facilitate access to care. Understanding the "web of causation" is key to developing any intervention to improve dental access in people with AD. Further research is needed from the perspective of other adult populations with lived experience of AD, as well as of dental professionals, to gain deeper insight into barriers, facilitators, and possible solutions., Knowledge Transfer Statement: The results of this study can help dental professionals understand factors affecting access to primary care in people with alcohol dependence to provide knowledge that may reduce stigma surrounding the disease. Results also demonstrate areas for intervention development for public policy., Competing Interests: Declaration of Conflicting InterestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
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9. Specialists' management of permanent dentition traumatic dental injuries in 7-16-year-olds: A qualitative study.
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Taylor GD, Gallichan N, Haq T, Sumner O, Albadri S, Holmes RD, and Waterhouse PJ
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- Humans, Child, Adolescent, Female, Male, United Kingdom, Interviews as Topic, Health Services Accessibility, Dental Care for Children organization & administration, Tooth Injuries therapy, Qualitative Research, Dentition, Permanent
- Abstract
Background/aim: Specialist paediatric dentists are integral to dental trauma care pathways. General dentists rely on specialist input, more so in complex cases. Little is known about specialists' role in these pathways or the perceived barriers they face. The aim is to explore specialists' role in managing traumatic dental injuries in the permanent dentition in children., Material/methods: Face-to-face (remote video) online semi-structured interviews were undertaken. All UK specialists were invited by email. Purposeful sampling aimed to investigate representation from the devolved nations, presence/absence of working within a managed-clinical network and level of care provision. Interviews were audio-recorded and transcribed verbatim. Transcripts were thematically analysed., Results: Data saturation was reached after nine interviews. Three main themes established were: inconsistent access to care; the need to formalise traumatic dental injuries care pathways; educationally upskilling general dentists. Geographical variation in provision of specialist and out-of-hours/emergency department care meant patients risked not receiving care by the most appropriate individual. Formalizing care pathways by clearly defining the role of each stakeholder (specialist, dentist, medical professionals and parents) and developing a method to assess complexity was perceived to be essential to improving treatment outcomes. Upskilling general dentists in trauma management appeared essential. A potential lack of engagement was raised, with a suggestion that trauma management education should become core continuing-professional development., Conclusions: Specialist input should be available in the management of traumatic dental injuries. Current access to specialist care is inequitable across the UK. Formalizing care pathways and upskilling general dentists could ease inconsistencies., (© 2024 The Authors. Dental Traumatology published by John Wiley & Sons Ltd.)
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- 2024
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10. Delivering smoking cessation interventions in NHS primary dental care - lessons from the ENHANCE-D trial.
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Weke A, Holmes RD, McColl E, Finch R, Butcher C, and Holliday R
- Abstract
Introduction Smoking is a major contributor to health inequalities in the UK. The ENHANCE-D trial is evaluating three smoking cessation interventions (nicotine replacement therapy [NRT], electronic cigarettes [ECs] or 'very brief advice') delivered in NHS primary dental care. This qualitative study aimed to provide insight into the factors that could influence the adoption of the interventions in these settings.Methods Interviews were conducted at two timepoints. Purposive maximum variation sampling was used to recruit and interview a total of 24 dental patients, 12 dental professionals and three NHS dental commissioners. Thematic analysis was carried out using normalisation process theory as an analytical framework.Results Dental settings were perceived as an appropriate location to deliver smoking cessation interventions. Patients had several motivating and demotivating factors regarding use of NRTs or ECs; they often had negative preconceptions. Financial considerations were major influencers for both patients and dental teams. The time pressures for dental practices were identified as a major barrier. Some practical issues, such as procurement and stock supply, would need to be considered if the ENHANCE-D interventions were to be implemented in routine practice.Conclusion Primary dental care teams are well-placed to deliver smoking cessation interventions. However, a number of facilitators and deterrents have been identified and strategic changes are needed for successful implementation., (© 2024. The Author(s).)
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- 2024
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11. Dental behaviour support: can we improve qualitative research on patient experience?
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Holmes RD
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- Humans, Dental Care standards, Qualitative Research
- Abstract
Data Sources: Databases included Embase, Medline (via OVID) and PsycINFO (via EBSCO). Studies referenced within included review articles were additionally screened for relevance., Study Selection: This review focused upon qualitative research studies and their use of dental behaviour support (DBS) tools to support dental care. Included studies were restricted to those in English and published since 1997. Screening of studies involved several authors according to pre-agreed inclusion and exclusion criteria. In the event of disagreement, a third author mediated the collaborative discussion., Data Extraction and Synthesis: Included studies first provided baseline study information including the type of qualitative research, the population studied and details of the type(s) of DBS under investigation. Then the qualitative data generated by each study, together with any interpretation provided by the authors, was entered onto bespoke data collection forms. A thematic synthesis approach was adopted. The authors generated new themes supported by selected quotations. The methodological quality of each included study was explored through a recognised tool and the level of confidence provided by each study was informed by the GRADE-CERQual assessment process., Results: Twenty-three studies were included. Most studies used semi-structured interviews, followed by focus groups and a small number of video diaries. For most studies, the focus was upon the dental care of children with a good proportion of these exploring dental general anaesthesia (DGA). Indeed, DGA was the most studied DBS technique. Whilst some studies explored adults' experiences of DBS, none of the included studies centred upon medically compromised or older adults. The review authors identified five themes following data synthesis. These themes included the following areas (abridged and modified from the review paper): trust; information sharing; control and autonomy; perceived treatment success and failure of DBS techniques; and the longer-term impact of DBS techniques upon patients., Conclusions: Qualitative research has more to offer our understanding of DBS techniques and the impact they have upon patient care experience. There is a need for research to explore a wider range of DBS techniques used in isolation or in combination. Patient reported experiences of care should be considered in the development of outcome measures and any related DBS Core Outcome Set., (© 2024. The Author(s).)
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- 2024
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12. Is food insecurity associated with dental caries?
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Holmes RD
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- Humans, Cross-Sectional Studies, Food Insecurity, Seizures, Observational Studies as Topic, Dental Caries epidemiology, Dental Caries etiology
- Abstract
Data Sources: Eight electronic databases including APA PsycINFO, CINAHL, Embase, LILACS, PubMed, Ovid, Scopus and Web of Science were searched from date of inception to November 2021. An updated search was conducted in August 2022. Google Scholar was accessed including Open Grey and ProQuest. Reference lists of the included studies were analysed for potentially eligible studies., Study Selection: Observational studies (cross-sectional, case-control and cohort) that evaluated the association between dental caries and food insecurity were eligible for analysis. Qualitative studies, reviews and meeting abstracts were excluded. There were no restrictions on language or publication date., Data Extraction and Synthesis: Two reviewers independently screened titles and abstracts. A third experienced researcher was consulted if there was disagreement. Food insecurity status was the exposure with dental caries the outcome. The authors retrieved effect measures, 95% CI's and P values where available. Heterogeneity was assessed via I
2 and R2 . A total of 514 records were initially identified. Once duplicates were removed, 19 references were assessed in full. The association between food insecurity and dental caries were presented as odds-ratios, relative risks and prevalence ratios with 95% CIs. A random-effects model was fitted to all meta-analyses., Results: Evaluation identified 14 studies for the qualitative synthesis and 7 studies for the quantitative synthesis. The total sample size for the 14 studies was 150,546 individuals. Quantitative data merged from two studies found food-insecure individuals more prone to dental caries than food-secure individuals (OR = 1.62; 95% CI, 1.01-2.60; P = 0.045). In two studies that used binary data to compare food security or insecurity, food insecure individuals were more likely to exhibit dental caries (OR = 1.66; 95% CI, 1.36-2.02; P < 0.0001)., Conclusions: People experiencing food insecurity are more likely to exhibit dental caries than those who have food security., (© 2024. The Author(s).)- Published
- 2024
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13. Deployment and assessment of a deep learning model for real-time detection of anal precancer with high frame rate high-resolution microendoscopy.
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Brenes D, Kortum A, Coole J, Carns J, Schwarz R, Vohra I, Richards-Kortum R, Liu Y, Cai Z, Sigel K, Anandasabapathy S, Gaisa M, and Chiao E
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- Humans, United States, Endoscopy, Diagnostic Imaging, Deep Learning, Anus Neoplasms diagnostic imaging, HIV Infections complications
- Abstract
Anal cancer incidence is significantly higher in people living with HIV as HIV increases the oncogenic potential of human papillomavirus. The incidence of anal cancer in the United States has recently increased, with diagnosis and treatment hampered by high loss-to-follow-up rates. Novel methods for the automated, real-time diagnosis of AIN 2+ could enable "see and treat" strategies, reducing loss-to-follow-up rates. A previous retrospective study demonstrated that the accuracy of a high-resolution microendoscope (HRME) coupled with a deep learning model was comparable to expert clinical impression for diagnosis of AIN 2+ (sensitivity 0.92 [P = 0.68] and specificity 0.60 [P = 0.48]). However, motion artifacts and noise led to many images failing quality control (17%). Here, we present a high frame rate HRME (HF-HRME) with improved image quality, deployed in the clinic alongside a deep learning model and evaluated prospectively for detection of AIN 2+ in real-time. The HF-HRME reduced the fraction of images failing quality control to 4.6% by employing a high frame rate camera that enhances contrast and limits motion artifacts. The HF-HRME outperformed the previous HRME (P < 0.001) and clinical impression (P < 0.0001) in the detection of histopathologically confirmed AIN 2+ with a sensitivity of 0.91 and specificity of 0.87., (© 2023. The Author(s).)
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- 2023
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14. Evaluation of student-perceived competence of interprofessional working in Gerodontology.
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Mullan F, Holmes RD, and Bateman HL
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- Humans, Aged, Surveys and Questionnaires, Curriculum, Health Personnel education, Students, Pharmacy
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Objective: To evaluate pharmacy, dental and dental therapy undergraduate students' perceived competence of interprofessional working before and after attending an interprofessional education (IPE) Gerodontology workshop., Background: Whilst there is international recognition of the importance of collaboration between the dental profession and systemic healthcare providers to enhance patient care, there remains a paucity of research into IPE in Gerodontology., Materials and Methods: Pharmacy, dental and dental therapy undergraduate students attended a 2-hour Gerodontology case-based workshop. Students completed anonymised Interprofessional Collaborative Competencies Attainment Surveys (ICCAS) before and after attendance., Results: 108 questionnaires were received, 7 were withdrawn (1 incomplete with only pre-workshop side completed, 6 did not identify degree programme). From 101 included questionnaires, 37 were from pharmacy, 56 dental and 8 dental therapy students resulting in response rates of 84%, 82% and 67%, respectively. Each student group recorded an increase in positive reflective competence median (IQR) after taking part in the workshop. Overall median (IQR) reflective competence before the workshop was 6 (1), 5 (2) and 6 (2) for pharmacy, dental and dental therapy students, respectively, which increased to 7 (1) for all groups. There was variability in reflective competence before attending the workshop between dental and pharmacy students for two questions, and dental and dental therapy students for two different questions., Conclusion: All students reported increased reflective competence of interprofessional working following the workshop. These findings suggest that introduction of IPE events into Gerodontology curricula may improve student understanding and appreciation of interprofessional working when providing care for older people., (© 2022 The Authors. Gerodontology published by Gerodontology Association and John Wiley & Sons Ltd.)
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- 2023
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15. Abstracts of Presentations to the Working Session on Improving Predictive Modeling of Mycotoxin Risk for Africa Held at the 3rd ASM2022 on 7 September 2022, in Stellenbosch, South Africa.
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Rembold F, Mvumi B, Miller D, Omari R, Battilani P, Galani YJH, Louw W, Falade TDO, Schweiger W, and Ermolli M
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In 2008, the African Postharvest Losses Information Systems project (APHLIS, accessed on 6 September 2022) developed an algorithm for estimating the scale of cereal postharvest losses (PHLs). The relevant scientific literature and contextual information was used to build profiles of the PHLs occurring along the value chains of nine cereal crops by country and province for 37 sub-Saharan African countries. The APHLIS provides estimates of PHL figures where direct measurements are not available. A pilot project was subsequently initiated to explore the possibility of supplementing these loss estimates with information on the aflatoxin risk. Using satellite data on drought and rainfall, a time series of agro-climatic aflatoxin risk warning maps for maize was developed covering the countries and provinces of sub-Saharan Africa. The agro-climatic risk warning maps for specific countries were shared with mycotoxin experts from those countries for review and comparison with their aflatoxin incidence datasets. The present Work Session was a unique opportunity for African food safety mycotoxins experts, as well as other international experts, to meet and deepen the discussion about prospects for using their experience and their data to validate and improve agro-climatic risk modeling approaches.
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- 2023
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16. Remote work and the COVID-19 pandemic: An artificial intelligence-based topic modeling and a future agenda.
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Aleem M, Sufyan M, Ameer I, and Mustak M
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As remote work has become more common than ever throughout the COVID-19 pandemic, it has drawn special attention from scholars. However, the outcome has been significantly sporadic and fragmented. In our systematic review, we use artificial intelligence-based machine learning tools to examine the relevant extant literature in terms of its dominant topics, diversity, and dynamics. Our results identify-eight research themes: (1) Effect on employees at a personal level, (2) Effect on employees' careers, (3) Family life and gender roles, (4) Health, well-being, and safety, (5) Labor market dynamics, (6) Economic implications, (7) Remote work management, (8) Organizational remote work strategies. With further content analysis, we structure the sporadic research into three overarching categories. Finally, for each category, we offer a detailed agenda for further research., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2022 Published by Elsevier Inc.)
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- 2023
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17. Imaging Review of Hockey-related Lower Extremity Injuries.
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Holmes RD, Yan YY, Mallinson PI, Andrews GT, Munk PL, and Ouellette HA
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- Humans, Incidence, Lower Extremity diagnostic imaging, Athletic Injuries diagnostic imaging, Hockey, Leg Injuries diagnostic imaging
- Abstract
Hockey is a fast-paced contact sport with a high incidence of injuries. Although injuries are more frequent among elite players, recreational hockey injuries are a common issue faced by primary care and emergency physicians. Lower extremity injuries in hockey are particularly important because they account for approximately a third of all injuries and > 60% of all overuse injuries. This pictorial review provides the general and specialty trained radiologist with a knowledge of the patterns of lower extremity injury that occur in ice hockey., Competing Interests: None declared., (Thieme. All rights reserved.)
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- 2022
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18. Imaging Review of Hockey-Related Upper Extremity Injuries.
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Yan YY, Holmes RD, Mallinson PI, Andrews GT, Munk PL, and Ouellette HA
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- Diagnostic Imaging, Humans, Incidence, Upper Extremity diagnostic imaging, Upper Extremity injuries, Arm Injuries diagnostic imaging, Athletic Injuries diagnostic imaging, Hockey
- Abstract
Ice hockey is a fast-paced contact sport with a high incidence of injuries. Upper extremity injury is one of the most common regions of the body to be injured in hockey. This imaging review will equip the radiologist with a knowledge of the more common and severe upper extremity injuries that occur in this sport., Competing Interests: None declared., (Thieme. All rights reserved.)
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- 2022
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19. Imaging of Hockey-related Injuries of the Head, Neck, and Body.
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Holmes RD, Walsh JP, Yan YY, Mallinson PI, Andrews GT, Munk PL, and Ouellette HA
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- Diagnostic Imaging, Humans, Athletic Injuries diagnostic imaging, Brain Concussion, Craniocerebral Trauma diagnostic imaging, Hockey
- Abstract
Hockey is a demanding contact sport with growing popularity around the world. This article is part of a review series in this issue of Seminars in Musculoskeletal Radiology that summarizes epidemiological research on the patterns of ice hockey injuries as well as provides pictorial examples for a radiologist's perspective. We focus on non-extremity pathologies which encompass many of the most devastating injuries of hockey, namely those involving the head, neck, face, spine, and body., Competing Interests: None declared., (Thieme. All rights reserved.)
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- 2022
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20. Implications of Cone Beam CT Peripheral Edge Blurring and Signal Attenuation for Interventional Procedures.
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Holmes RD, Thakur Y, and Mallinson P
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- Humans, Phantoms, Imaging, Cone-Beam Computed Tomography methods
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- 2022
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21. Resource Allocation in a National Dental Service Using Program Budgeting Marginal Analysis.
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Vernazza CR, Carr K, Holmes RD, Wildman J, Gray J, Exley C, Smith RA, and Donaldson C
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Introduction: In any health system, choices must be made about the allocation of resources (budget), which are often scarce. Economics has defined frameworks to aid resource allocation, and program budgeting marginal analysis (PBMA) is one such framework. In principle, patient and public values can be incorporated into these frameworks, using techniques such as willingness to pay (WTP). However, this has not been done before, and few formal resource allocation processes have been undertaken in dentistry. This study aimed to undertake a PBMA with embedded WTP values in a national dental setting., Methods: The PBMA process was undertaken by a panel of participant-researchers representing commissioners, dentists, dental public health staff, and academics. The panel reviewed current allocations and generated a set of weighted criteria to evaluate services against. Services to be considered for removal and investment were determined by the panel and wider discussion and then scored against the criteria. Values from a nationally representative WTP survey of the public contributed to the scores for interventions. Final decisions on removal and investment were taken after panel discussion using individual anonymous electronic voting., Results: The PBMA process resulted in recommendations to invest in new program components to improve access to general dentists, care home dentistry, and extra support for dental public health input into local government decisions. Disinvestments were recommended in orthodontics and to remove routine scaling and polishing of teeth., Discussion: The PBMA process was successful in raising awareness of resource allocation issues. Implementation of findings will depend on the ability of decision makers to find ways of operationalizing the decisions. The process illustrates practical aspects of the process that future dental PBMAs could learn from., Knowledge Transfer Statement: This study illustrates a framework for resource allocation in dental health services and will aid decision makers in implementing their own resource allocation systems.
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- 2021
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22. Healthcare System-to-System Cost Variability in the Care of Pediatric Abdominal Pain-Associated Functional Gastrointestinal Disorders.
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Livitz M, Friesen AS, Glynn EF, Schurman JV, Colombo JM, and Friesen CA
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The purpose of this study was to assess cost variability in the care of abdominal pain-associated functional gastrointestinal disorders (AP-FGIDS) in youth across health systems, races, and specific AP-FGID diagnoses. Patients, aged 8-17 years, with a priority 1 diagnosis corresponding to a Rome IV defined AP-FGID were identified within the Health Facts
® database. Total costs were obtained across the continuum of care including outpatient clinics, emergency department, and inpatient or observation units. Cost variability was described comparing different health systems, races, and diagnoses. Thirteen thousand two hundred and fourteen patients were identified accounting for 17,287 encounters. Total costs were available for 38.7% of the encounters. There was considerable variability in costs within and, especially, across health systems. Costs also varied across race, urban vs. rural site of care, and AP-FGID diagnoses. In conclusion, there was considerable variability in the costs for care of AP-FGIDs which is sufficient to support multi-site studies to understand the value of specific tests and treatments. Significant differences in costs by race merit further investigation to understand key drivers.- Published
- 2021
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23. Nonlesional diffusely abnormal appearing white matter in clinically isolated syndrome: Prevalence, association with clinical and MRI features, and risk for conversion to multiple sclerosis.
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Holmes RD, Vavasour IM, Greenfield J, Zhao G, Lee JS, Moore GRW, Tam R, Metz LM, Trablousee A, Li DKB, and Laule C
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- Brain diagnostic imaging, Disease Progression, Humans, Magnetic Resonance Imaging, Prevalence, Multiple Sclerosis diagnostic imaging, Multiple Sclerosis epidemiology, White Matter diagnostic imaging
- Abstract
Background and Purpose: While diffusely abnormal white matter (DAWM) is a nonlesional MRI abnormality identified in ∼25% of patients with multiple sclerosis (MS), it has yet to be investigated in patients at an earlier disease stage, namely clinically isolated syndrome (CIS). The goals of this study were to (1) determine the prevalence of DAWM in patients with a CIS suggestive of MS, (2) evaluate the association between DAWM and demographic, clinical, and MRI features, and (3) evaluate the prognostic significance of DAWM on conversion from CIS to MS., Methods: One hundred and forty-two CIS participants were categorized into DAWM and non-DAWM groups at baseline and followed for up to 24 months or until MS diagnosis. The primary outcome was conversion to MS (2005 McDonald criteria) within 6 months., Results: DAWM was present in 27.5% of participants, and was positively associated with brainstem symptom onset, receiving corticosteroids, dissemination in space, and T
2 lesion volume. DAWM was associated with an increased risk of conversion to MS over 6 months after adjustment for age and disability (hazard ratio [HR] = 2.24, p = 0.004). This association remained at a trend-level after adjustment for high-risk imaging features (HR = 1.68, p = 0.10)., Conclusions: DAWM is present in a similar proportion of patients with CIS and clinically definite MS, and it is associated with increased risk of conversion to MS over 6 months., (© 2021 American Society of Neuroimaging.)- Published
- 2021
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24. The role of local radio in promoting creative engagement for healthy ageing.
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Vella-Burrows TP, Ewbank N, and Philips J
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- Aged, Communication, Humans, Mass Media, Healthy Aging
- Abstract
Objectives: To identify and critique literature on the links between public service local radio promoting creative engagement for healthy ageing in order to better understand the potential for public health agendas., Methods: This communication draws on preliminary learning from Up for Arts (UfA), a partnership initiative between BBC local radio and the UK charity Voluntary Arts. As part of the development of a logic model for the national roll-out of UfA, a scoping review of literature was undertaken. Eight search engines were searched systematically using four main search terms, 'older people', 'participatory arts', 'mass media' and 'public health'. Journals and websites were also opportunistically searched for outlying material. The inclusion criteria were qualitative, quantitative and mixed method studies and literature reviews published in English, between 2009 and 2018, wherein public service local radio was involved in promoting arts and crafts activities in local communities. Both formal activities, such as singing in a choir, and informal activities, such as a home-based knitting circle, were included. Art therapy, music therapy and other clinical interventions were excluded., Results: Of 708 papers, articles and reports identified through title, 37 were retained for primary screening. None met the criteria for inclusion. However, results on the individual search topics indicate that improved public health outcomes might result by including the promotion of creative engagement for healthy ageing., Conclusion: Public Service Local Radio partnership initiatives, such as UfA, could have a role in supporting the development of creative engagement as a positive healthy ageing activity. This may be of interest and relevance to policymakers seeking novel ways to address health behaviours among people approaching old age., (Copyright © 2021 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.)
- Published
- 2021
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25. Reducing neuroimaging in first-episode psychosis by facilitating uptake of choosing wisely recommendations: a quality improvement initiative.
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Srivastava R, Holmes RD, Noel CW, Lam TV, and Shewchuk JR
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- Humans, Neuroimaging, Practice Patterns, Physicians', Unnecessary Procedures, Psychotic Disorders diagnosis, Quality Improvement
- Abstract
Competing Interests: Competing interests: None declared.
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- 2021
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26. Practical Approach to Radiopaque Jaw Lesions.
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Holmes KR, Holmes RD, Martin M, and Murray N
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- Diagnosis, Differential, Humans, Radiography
- Abstract
Radiopaque lesions of the jaw are myriad in type and occasionally protean in appearance. In turn, the radiologic analysis of these lesions requires a systematic approach and a broad consideration of clinical and imaging characteristics to enable reliable radiologic diagnosis. Initially categorizing lesions by attenuation pattern provides a practical framework for organizing radiopaque jaw lesions that also reflects important tissue characteristics. Specifically, the appearance of radiopaque lesions can be described as (a) densely sclerotic, (b) ground glass, or ( c ) mixed lytic-sclerotic, with each category representing a distinct although occasionally overlapping differential diagnosis. After characterizing attenuation pattern, the appreciation of other radiologic features, such as margin characteristics or relationship to teeth, as well as clinical features including demographics and symptoms, can aid in further narrowing the differential diagnosis and lend confidence to clinical decision making. The authors review the potential causes of a radiopaque jaw lesion, including pertinent clinical and radiologic features, and outline a simplified approach to its radiologic diagnosis, with a focus on cross-sectional CT. An invited commentary by Buch is available online.
© RSNA, 2021.- Published
- 2021
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27. An analysis of advanced and specialist posts in diagnostic radiography: Do job descriptions describe advanced practice?
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Harris MA, Snaith B, Adamson HK, Foster B, and Woznitza N
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- Humans, Leadership, Radiography, Allied Health Personnel, Job Description
- Abstract
Introduction: Underpinned by a multi professional advanced clinical practice (ACP) framework, role consistency in practice level and education has been advocated across allied health professions. However little research has evaluated ACP expectations in radiography. This study identified the capability requirements of advanced and specialist diagnostic radiographers and mapped these to home country advanced practice frameworks and the Society and College of Radiographers (SCoR) Education and Career Framework., Methods: A consecutive sample of UK job advertisements was collected over six months and analysed for role focus, professional and clinical responsibilities, reporting or procedural expectations and knowledge and experience. Qualitative content analysis was used to scrutinise capabilities during role mapping., Results: A total of 42 job descriptions were analysed across UK Trusts and Health Boards, with 31 roles (73.8%) containing the terms advanced or specialist. Half of the advertised roles expected proficiency in reporting (n = 21; 50%). Responsibilities mapped to the practice outcomes of the SCoR framework in 31 roles (n = 31/42; 73.8%). The English documents (n = 40/42; 95.2%) evaluated against the multi professional framework identified significantly (χ2 = 14.6; p < 0.01) fewer capabilities (n = 13/40; 32.5%). Clinical practice was reflected broadly in textual behavioural descriptors however, leadership, education and research responsibilities were internal and operational in nature., Conclusion: This analysis of diagnostic radiographer job descriptions has demonstrated that many posts advertised as 'advanced' differ from advanced practice roles defined by the multi professional ACP framework, although they meet professional body standards., Implications for Practice: Utilisation of diagnostic radiographers as 'true' advanced clinical practitioners remains intermittent. Greater consistency in job descriptions is required to strengthen radiography advanced practice and support radiographer development., (Copyright © 2020 The College of Radiographers. Published by Elsevier Ltd. All rights reserved.)
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- 2021
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28. Colonic stool burden on computed tomography does not correlate with bowel habit: a cross-sectional study.
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Ferguson D, Holmes RD, Scott R, Alsahafi M, Buckley J, Donnellan F, and Prichard DO
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- Cross-Sectional Studies, Habits, Humans, Reproducibility of Results, Defecation, Tomography, X-Ray Computed
- Abstract
Purpose: Stool burden on abdominal radiographs is not reflective of constipation, perhaps because of variable fecal shadowing or limited inter-rater agreement. These limitations are hypothetically mitigated by computed tomography (CT). This research aimed (i) to evaluate whether bowel movement frequency, stool form, or a diagnosis of functional constipation correlate or associate with stool burden identified on CT, and (ii) to investigate whether physicians use CT in their assessment of a patients' bowel function., Methods: Patients attending for non-emergent abdominal CT imaging were invited to participate by completing a bowel questionnaire. Stool burden identified on imaging was determined and inter-rater reliability was evaluated in a subgroup of patients (n = 20). Descriptive and comparative analyses were performed. An online questionnaire evaluated the use of abdominal imaging in assessing patients' bowel function in a cross-section of ordering physicians., Results: The patient response rate was 19% (96/516). No clinically useful associations between fecal burden and stool form, bowel motion frequency, gastrointestinal symptoms or a diagnosis of constipation was identified. The physician response rate was 35% (33/94). Opportunistic use of data was more common than deliberate use. However, an abdominal radiograph or CT scan had been requested by 42% and 18% of physicians respectively to assess patient's chronic bowel habit. Approximately 30% of physicians believed evidence supported this practice., Conclusions: Physicians may use abdominal CT in their assessment of patients' chronic bowel habits. However, objective assessment does not support this practice. Colonic stool burden does not correlate with patient-reported symptoms or a criteria-based diagnosis of constipation.
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- 2021
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29. Transatlantic engagement: a novel dental educational exchange.
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Waterhouse PJ, Kowolik JE, Schrader SM, Howe D, and Holmes RD
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- England, Humans, United States, Universities, Curriculum, Education, Dental
- Abstract
Introduction Newcastle University School of Dental Sciences (NUSDS) and Indiana University School of Dentistry in the United States of America (IUSD) are like-minded institutions committed to civic engagement. Over the last 15 years, both universities have built civic engagement into the dental curricula, however each institution operates within significantly different healthcare systems.Aim Co-development of unique collaborative dental education; the first UK/US educational exchange programme engaged with the dental student community.Design A dental educational exchange was developed enabling NUSDS and IUSD students to learn alongside each other within dental and community settings in both countries. Students participate in a unique face-to-face collaborative and interdisciplinary education programme within respective dental schools and by a series of video conferences scheduled before on-site visits. They gain mutual awareness of delivery, access to care and possible barriers facing patients relating to the oral healthcare systems in England, the state of Indiana and the USA. Logistical considerations were significant, aided by scoping visits to the respective partner school and video conferencing. Planning encompassed timetable restrictions, scheduling student video conferences, students' clinical access/observerships, occupational health clearances, overall educational content, student/staff evaluation and potential areas for education research.Conclusions Currently in its fourth year, this is a unique example of a collaborative educational exchange between the UK and USA.
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- 2020
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30. Development and retention of the dental workforce: findings from a regional workforce survey and symposium in England.
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Holmes RD, Burford B, and Vance G
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- Adult, Congresses as Topic, England, Female, Humans, Male, Middle Aged, Surveys and Questionnaires, Dental Care organization & administration, Health Workforce organization & administration, Personnel Loyalty, Primary Health Care organization & administration, Staff Development
- Abstract
Background: To help promote a flexible and sustainable workforce in dentistry, it is necessary to access accurate and timely data about the structure and nature of the evolving dental team. This paper considers the results and learning from a region-wide dental workforce survey conducted in one area of Health Education England and how the team has changed since the last survey a decade earlier., Methods: A mixed-methods approach comprised two phases. In Phase 1 a customised workforce questionnaire was sent to all dental practices registered with the Care Quality Commission in the North East of England and North Cumbria in March 2016. Findings then informed Phase 2, a regional symposium held in October 2016, where interactive workshops generated qualitative data that elaborated on factors influencing workforce development., Results: Of 431 primary dental care practices identified, 228 questionnaires were returned - a 53% response rate. The largest professional groups were dental nurses (n = 1269, 53% by headcount; 50% of fte) and dentists (34% by headcount; 42% by fte), though there had been increases in numbers of all staff groups over the decade, which was most marked for dental therapists (from 1 per 39 dentists to 1 per 8 dentists). The dental team predominantly fell into 'younger' age groups (< 46 years age), with evidence of a significant increase in the number of dentists reporting part-time working in a practice since the last survey. Around one third of dental practices reported employing dental nurses with additional skills (n = 74, 32.5%) or dental therapists (n = 73, 32%), and nearly half employed a dental hygienist (n = 104, 46%). However, there was considerable variability in whether these staff actually carried out the range of skills within their scope of practice. Factors shaping workforce development were identified as, the national context, loss of expertise, patients' health needs and expectations, surgery premises and financial constraints., Conclusions: The composition and work patterns of the primary care dental workforce have changed markedly over the last decade, though utilisation of skill-mix continues to be constrained. Consideration of factors determining career progression of dentists and dental care professionals is needed to optimise a sustainable future workforce.
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- 2020
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31. Children and parents' perspectives on the acceptability of three management strategies for dental caries in primary teeth within the 'Filling Children's Teeth: Indicated or Not' (FiCTION) randomised controlled trial - a qualitative study.
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El-Yousfi S, Innes NPT, Holmes RD, Freeman R, Cunningham KB, McColl E, Maguire A, Douglas GVA, Clarkson JE, and Marshman Z
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- Adult, Child, Child, Preschool, Dental Care, Female, Humans, Male, Qualitative Research, Tooth, Deciduous, Dental Caries prevention & control, Dental Caries therapy, Parents psychology, Patient Acceptance of Health Care psychology, Randomized Controlled Trials as Topic
- Abstract
Background: The Filling Children's Teeth: Indicated Or Not? (FiCTION) randomised controlled trial (RCT) aimed to explore the clinical- and cost-effectiveness of managing dental caries in children's primary teeth. The trial compared three management strategies: conventional caries management with best practice prevention (C + P), biological management with best practice prevention (B + P) and best practice prevention alone (PA)-based approaches. Recently, the concept of treatment acceptability has gained attention and attempts have been made to provide a conceptual definition, however this has mainly focused on adults. Recognising the importance of evaluating the acceptability of interventions in addition to their effectiveness, particularly for multi-component complex interventions, the trial design included a qualitative component. The aim of this component was to explore the acceptability of the three strategies from the perspectives of the child participants and their parents., Methods: Qualitative exploration, based on the concept of acceptability. Participants were children already taking part in the FiCTION trial and their parents. Children were identified through purposive maximum variation sampling. The sample included children from the three management strategy arms who had been treated and followed up; median (IQR) follow-up was at 33.8 (23.8, 36.7) months. Semi-structured interviews with thirteen child-parent dyads. Interviews were transcribed verbatim and analysed using a framework approach., Results: Data saturation was reached after thirteen interviews. Each child-parent dyad took part in one interview together. The participants were eight girls and five boys aged 5-11 years and their parents. The children's distribution across the trial arms was: C + P n = 4; B + P n = 5; PA n = 4. Three key factors influenced the acceptability of caries management in primary teeth to children and parents: i) experiences of specific procedures within management strategies; ii) experiences of anticipatory dental anxiety and; iii) perceptions of effectiveness (particularly whether pain was reduced). These factors were underpinned by a fourth key factor: the notion of trust in the dental professionals - this was pervasive across all arms., Conclusions: Overall children and parents found each of the three strategies for the management of dental caries in primary teeth acceptable, with trust in the dental professional playing an important role.
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- 2020
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32. Dental professionals' experiences of managing children with carious lesions in their primary teeth - a qualitative study within the FiCTION randomised controlled trial.
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Marshman Z, Kettle JE, Holmes RD, Cunningham KB, Freeman R, Gibson BJ, McColl E, Maguire A, Douglas GVA, Clarkson JE, and Innes NPT
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- Adult, Child, Dental Caries pathology, Dental Caries prevention & control, Humans, Interviews as Topic, Middle Aged, Pediatric Dentistry, Qualitative Research, United Kingdom, Dental Assistants psychology, Dental Care for Children methods, Dental Caries therapy, Dentists psychology, Tooth, Deciduous pathology
- Abstract
Background: The lack of evidence for the effective management of carious lesions in children's primary teeth has caused uncertainty for the dental profession and patients. Possible approaches include conventional and biological management alongside best practice prevention, and best practice prevention alone. The FiCTION trial assessed the effectiveness of these options, and included a qualitative study exploring dental professionals' (DPs) experiences of delivering the different treatment arms. This paper reports on how DPs managed children with carious lesions within FiCTION and how this related to their everyday experiences of doing dentistry., Methods: Overall, 31 DPs from FiCTION-trained dental surgeries in four regions of the UK participated in semi-structured interviews about their experiences of the three treatment arms (conventional management of carious lesions and prevention (C + P), biological management of carious lesions and prevention (B + P) or prevention alone (PA)). A theoretical framework, drawing on social practice theory (SPT), was developed for analysis., Results: Participants discussed perceived effectiveness of, and familiarity with, the three techniques. The C + P arm was familiar, but some participants questioned the effectiveness of conventional restorations. Attitudes towards the B + P arm varied in terms of familiarity, but once DPs were introduced to the techniques, this was seen as effective. While prevention was familiar, PA was described as ineffective. DPs manage children with carious lesions day-to-day, drawing on previous experience and knowledge of the child to provide what they view as the most appropriate treatment in the best interests of each child. Randomisation undermined these normal choices. Several DPs reported deviating from the trial arms in order to treat a patient in a particular way. Participants valued evidence-based dentistry, and expect to use the results of FiCTION to inform future practice. They anticipate continuing to use the full range of treatment options, and to personally select appropriate strategies for individual children., Conclusions: RCTs take place in the context of day-to-day practices of doing dentistry. DPs employ experiential and interpersonal knowledge to act in the best interests of their patients. Randomisation within a clinical trial can present a source of tension for DPs, which has implications for assuring individual equipoise in future trials.
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- 2020
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33. Brain Myelin Water Fraction and Diffusion Tensor Imaging Atlases for 9-10 Year-Old Children.
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Morris SR, Holmes RD, Dvorak AV, Liu H, Yoo Y, Vavasour IM, Mazabel S, Mädler B, Kolind SH, Li DKB, Siegel L, Beaulieu C, MacKay AL, and Laule C
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- Child, Female, Humans, Male, Brain diagnostic imaging, Diffusion Tensor Imaging methods, Myelin Sheath chemistry, Water, White Matter diagnostic imaging
- Abstract
Background and Purpose: Myelin water imaging (MWI) and diffusion tensor imaging (DTI) provide information about myelin and axon-related brain microstructure, which can be useful for investigating normal brain development and many childhood brain disorders. While pediatric DTI atlases exist, there are no pediatric MWI atlases available for the 9-10 years old age group. As myelination and structural development occurs throughout childhood and adolescence, studies of pediatric brain pathologies must use age-specific MWI and DTI healthy control data. We created atlases of myelin water fraction (MWF) and DTI metrics for healthy children aged 9-10 years for use as normative data in pediatric neuroimaging studies., Methods: 3D-T
1 , DTI, and MWI scans were acquired from 20 healthy children (mean age: 9.6 years, range: 9.2-10.3 years, 4 females). ANTs and FSL registration were used to create quantitative MWF and DTI atlases. Region of interest (ROI) analysis in nine white matter regions was used to compare pediatric MWF with adult MWF values from a recent study and to investigate the correlation between pediatric MWF and DTI metrics., Results: Adults had significantly higher MWF than the pediatric cohort in seven of the nine white matter ROIs, but not in the genu of the corpus callosum or the cingulum. In the pediatric data, MWF correlated significantly with mean diffusivity, but not with axial diffusivity, radial diffusivity, or fractional anisotropy., Conclusions: Normative MWF and DTI metrics from a group of 9-10 year old healthy children provide a resource for comparison to pathologies. The age-specific atlases are ready for use in pediatric neuroimaging research and can be accessed: https://sourceforge.net/projects/pediatric-mri-myelin-diffusion/., (© 2020 by the American Society of Neuroimaging.)- Published
- 2020
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34. Best-practice prevention alone or with conventional or biological caries management for 3- to 7-year-olds: the FiCTION three-arm RCT.
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Maguire A, Clarkson JE, Douglas GV, Ryan V, Homer T, Marshman Z, McColl E, Wilson N, Vale L, Robertson M, Abouhajar A, Holmes RD, Freeman R, Chadwick B, Deery C, Wong F, and Innes NP
- Subjects
- Child, Child, Preschool, Female, Humans, Male, Pain, United Kingdom, Cost-Benefit Analysis, Dental Caries Susceptibility, Fluorides, Topical therapeutic use, Pit and Fissure Sealants, Tooth, Deciduous, Toothbrushing
- Abstract
Background: Historically, lack of evidence for effective management of decay in primary teeth has caused uncertainty, but there is emerging evidence to support alternative strategies to conventional fillings, which are minimally invasive and prevention orientated., Objectives: The objectives were (1) to assess the clinical effectiveness and cost-effectiveness of three strategies for managing caries in primary teeth and (2) to assess quality of life, dental anxiety, the acceptability and experiences of children, parents and dental professionals, and caries development and/or progression., Design: This was a multicentre, three-arm parallel-group, participant-randomised controlled trial. Allocation concealment was achieved by use of a centralised web-based randomisation facility hosted by Newcastle Clinical Trials Unit., Setting: This trial was set in primary dental care in Scotland, England and Wales., Participants: Participants were NHS patients aged 3-7 years who were at a high risk of tooth decay and had at least one primary molar tooth with decay into dentine, but no pain/sepsis., Interventions: Three interventions were employed: (1) conventional with best-practice prevention (local anaesthetic, carious tissue removal, filling placement), (2) biological with best-practice prevention (sealing-in decay, selective carious tissue removal and fissure sealants) and (3) best-practice prevention alone (dietary and toothbrushing advice, topical fluoride and fissure sealing of permanent teeth)., Main Outcome Measures: The clinical effectiveness outcomes were the proportion of children with at least one episode (incidence) and the number of episodes, for each child, of dental pain or dental sepsis or both over the follow-up period. The cost-effectiveness outcomes were the cost per incidence of, and cost per episode of, dental pain and/or dental sepsis avoided over the follow-up period., Results: A total of 72 dental practices were recruited and 1144 participants were randomised (conventional arm, n = 386; biological arm, n = 381; prevention alone arm, n = 377). Of these, 1058 were included in an intention-to-treat analysis (conventional arm, n = 352; biological arm, n = 352; prevention alone arm, n = 354). The median follow-up time was 33.8 months (interquartile range 23.8-36.7 months). The proportion of children with at least one episode of pain or sepsis or both was 42% (conventional arm), 40% (biological arm) and 45% (prevention alone arm). There was no evidence of a difference in incidence or episodes of pain/sepsis between arms. When comparing the biological arm with the conventional arm, the risk difference was -0.02 (97.5% confidence interval -0.10 to 0.06), which indicates, on average, a 2% reduced risk of dental pain and/or dental sepsis in the biological arm compared with the conventional arm. Comparing the prevention alone arm with the conventional arm, the risk difference was 0.04 (97.5% confidence interval -0.04 to 0.12), which indicates, on average, a 4% increased risk of dental pain and/or dental sepsis in the prevention alone arm compared with the conventional arm. Compared with the conventional arm, there was no evidence of a difference in episodes of pain/sepsis among children in the biological arm (incident rate ratio 0.95, 97.5% confidence interval 0.75 to 1.21, which indicates that there were slightly fewer episodes, on average, in the biological arm than the conventional arm) or in the prevention alone arm (incident rate ratio 1.18, 97.5% confidence interval 0.94 to 1.48, which indicates that there were slightly more episodes in the prevention alone arm than the conventional arm). Over the willingness-to-pay values considered, the probability of the biological treatment approach being considered cost-effective was approximately no higher than 60% to avoid an incidence of dental pain and/or dental sepsis and no higher than 70% to avoid an episode of pain/sepsis., Conclusions: There was no evidence of an overall difference between the three treatment approaches for experience of, or number of episodes of, dental pain or dental sepsis or both over the follow-up period., Future Work: Recommendations for future work include exploring barriers to the use of conventional techniques for carious lesion detection and diagnosis (e.g. radiographs) and developing and evaluating suitable techniques and strategies for use in young children in primary care., Trial Registration: Current Controlled Trials ISRCTN77044005., Funding: This project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme and will be published in full in Health Technology Assessment ; Vol. 24, No. 1. See the NIHR Journals Library website for further project information., Competing Interests: Elaine McColl was a member of the National Institute for Health Research (NIHR) Journals Library Editorial Group from 2013 to 2016; her employer was remunerated for her work in this regard. Luke Vale was a member of the NIHR Health Technology Assessment (HTA) Clinical Trials Board for a period of time between the years 2014 and 2018. Nicola PT Innes received a grant from The 3M Company (Maplewood, MN, USA)/ESPE to support a Clinical Fellowship in 2000; the work investigated the Hall Technique, which forms an aspect of one arm of the randomised controlled trial reported in this work. The results of the trial were reported independently.
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- 2020
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35. Child Caries Management: A Randomized Controlled Trial in Dental Practice.
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Innes NP, Clarkson JE, Douglas GVA, Ryan V, Wilson N, Homer T, Marshman Z, McColl E, Vale L, Robertson M, Abouhajar A, Holmes RD, Freeman R, Chadwick B, Deery C, Wong F, and Maguire A
- Subjects
- Child, Child, Preschool, Dentists, Humans, Pit and Fissure Sealants, Professional Role, Tooth, Deciduous, Dental Caries prevention & control, Dental Caries therapy
- Abstract
This multicenter 3-arm, parallel-group, patient-randomized controlled trial compared clinical effectiveness of 3 treatment strategies over 3 y for managing dental caries in primary teeth in UK primary dental care. Participants aged 3 to 7 y with at least 1 primary molar with dentinal carious lesion were randomized across 3 arms (1:1:1 via centrally administered system with variable-length random permuted blocks): C+P, conventional carious lesion management (complete carious tooth tissue removal and restoration placement) with prevention; B+P, biological management (sealing in carious tooth tissue restoratively) with prevention; and PA, prevention alone (diet, plaque removal, fluorides, and fissure sealants). Parents, children, and dentists were not blind to allocated arm. Co-primary outcomes were 1) the proportion of participants with at least 1 episode of dental pain and/or infection and 2) the number of episodes of dental pain and/or infection during follow-up (minimum, 23 mo). In sum, 1,144 participants were randomized (C+P, n = 386; B+P, n = 381; PA, n = 377) by 72 general dental practitioners, of whom 1,058 (C+P, n = 352; B+P, n = 352; PA, n = 354) attended at least 1 study visit and were included in the primary analysis. The median follow-up was 33.8 mo (interquartile range, 23.8 to 36.7). Proportions of participants with at least 1 episode of dental pain and/or infection were as follows: C+P, 42%; B+P, 40%; PA, 45%. There was no evidence of a difference in incidence of dental pain and/or infection when B+P (adjusted risk difference [97.5% CI]: -2% [-10% to 6%]) or PA (4% [-4% to 12%]) was compared with C+P. The mean (SD) number of episodes of dental pain and/or infection were as follows: C+P, 0.62 (0.95); B+P, 0.58 (0.87); and PA, 0.72 (0.98). Superiority could not be concluded for number of episodes between B+P (adjusted incident rate ratio (97.5% CI): 0.95 [0.75 to 1.21]) or PA (1.18 [0.94 to 1.48]) and C+P. In conclusion, there was no evidence of a difference among the 3 treatment approaches for incidence or number of episodes of dental pain and/or infection experienced by these participants with high caries risk and established disease (trial registration: ISRCTN77044005).
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- 2020
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36. Systematic Review of Evidence Pertaining to Factors That Modify Risk of Early Childhood Caries.
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Moynihan P, Tanner LM, Holmes RD, Hillier-Brown F, Mashayekhi A, Kelly SAM, and Craig D
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- Child, Child, Preschool, Female, Fluorides, Humans, Infant, Oral Health, Oral Hygiene, Toothpastes, Dental Caries
- Abstract
Introduction: A systematic review of evidence on the impact of modifiable risk factors on early childhood caries (ECC) was conducted to inform recommendations in a World Health Organization manual on ECC prevention., Objectives: To systematically review published evidence pertaining to the effect of modifiable risk factors on ECC., Methods: Twelve questions relating to infant feeding, diet, oral hygiene, and fluoride were addressed, as prioritized by a World Health Organization expert panel. Questions pertaining to the use of fluoride toothpaste were excluded due to its proven efficacy. The target population was children aged <72 mo. Data sources included Medline, Embase, CINAHL, and PubMed, and all human epidemiologic studies were included. The highest level of evidence was used for evidence synthesis and, where possible, meta-analysis. The review was conducted in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) statement, with evidence assessed via the GRADE method., Results: Of the 13,831 papers identified, 627 were screened in duplicate; of these, 139 were included. The highest-level evidence indicated that breastfeeding ≤24 mo does not increase ECC risk but suggested that longer-duration breastfeeding increases risk (low-quality evidence). Low-quality evidence indicated increased risk associated with consumption of sugars in bottles. Only 1 study had data on the impact of sugars in complementary foods, which increased risk. Moderate-quality evidence showed a benefit of oral health education for caregivers (odds ratio, 0.39; 95% CI, 0.19 to 0.80, P = 0.009). Meta-analysis of data on the impact on ECC from living in a fluoridated area showed a significant effect (mean difference, -1.25; 95% CI, -1.24 to -0.36; P = 0.006). Limited moderate- and low-quality data indicated a benefit of fluoride exposure from salt and milk, respectively., Conclusion: The best available evidence indicates that breastfeeding up to 2 y of age does not increase ECC risk. Providing access to fluoridated water and educating caregivers are justified approaches to ECC prevention. Limiting sugars in bottles and complementary foods should be part of this education., Knowledge Transfer Statement: This research is being used by the World Health Organization in developing a toolkit on the prevention and management of early childhood caries. The information will guide 1) governments in developing national oral health plans and 2) clinicians when providing preventive advice, including that regarding infant feeding practices. It will help ensure that advice is in line with current World Health Organization guidelines and the best available evidence.
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- 2019
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37. Meeting the needs of patients with disabilities: how can we better prepare the new dental graduate?
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Wilson KE, Dunn K, Holmes RD, and Delgaty L
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- Curriculum, Humans, Learning, Persons with Disabilities, Students, Dental
- Abstract
Background Over the last two decades, the introduction of equality legislation has resulted in disabled people having improved opportunities and better access to services. Within the field of oral health care, the specialty of special care dentistry exists to act as an advocate for those with disabilities and it is recognised that there is a need to reduce health inequalities. To ensure the future dental workforce is able to respond to the needs of those with disabilities, education is key. This raises the question: 'are we adequately preparing future dental professionals to fulfil their obligations?'.Aim To explore final year dental students' insight into issues of disability in order to inform the undergraduate special care dentistry programme.Method Qualitative methods using focus groups were employed to address the research issue. The data were analysed using thematic analysis.Results Four main themes were identified: 'perceptions of disability', 'experience of disability', 'patient management' and 'teaching and learning'. The level of preparedness varied among students and could be attributed to: knowledge of disability issues; previous experience of people with disabilities; how education in the field of special care dentistry was delivered. Students identified the need for more structure to their teaching and increased exposure to the disabled community.Conclusion The issues identified reflect current literature and highlight the importance of addressing disability within the wider undergraduate curriculum. Responding to the 'student voice' has the potential to tailor elements of the special care dentistry programme, in order to address their educational needs.
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- 2019
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38. A Pilot Study to Assess Feasibility of Lay Representation in Dental School Admissions Interviews.
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Bateman H, Smith M, Melvin C, Holmes RD, and Valentine RA
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- Aged, Faculty, Dental, Feasibility Studies, Female, Humans, Interviews as Topic, Male, Middle Aged, Pilot Projects, United Kingdom, School Admission Criteria, Schools, Dental organization & administration
- Abstract
Regulatory bodies in the dental profession often include members of the public as a way to ensure that patient interests are represented. With student selection for admission to dental school being a multifaceted, highly competitive process, this study was motivated by curiosity about the value of involving members of the public in the admissions process. At Newcastle University School of Dental Sciences, UK, semi-structured selection interviews conducted by two members of the faculty staff are part of the process. In the 2016-17 and 2017-18 admissions cycles, four lay representatives joined a number of the interview sessions. The aim of this study was to determine the feasibility of having a lay person present during the selection interview and whether this could become an integral part of the admissions process. A secondary purpose was to internally validate the processes in place for the interviews by considering the alignment of judgments of the panel and lay representatives. This study followed a two-stage, mixed-methods design. Quantitative analysis compared numerical interview scores awarded by the panel and lay representative when present. Scores for each question domain and overall interview score were compared. Qualitative analysis was carried out by conducting a focus group with lay representatives to seek insight into their experience and reflections on the interview processes. Thematic analysis was used, and overarching themes identified. The results showed no statistically significant difference between the interview panel and lay persons' scores for each domain or overall score awarded for the interview. The thematic analysis identified three overarching themes: reason for volunteering, process and training, and thoughts on style of interview used. These results suggest that involvement of lay people from the local community was feasible, and there was interest in continuing this involvement from the volunteers themselves.
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- 2019
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39. Health visitors' views on promoting oral health and supporting clients with dental health problems: a qualitative study.
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Lewney J, Holmes RD, Rankin J, and Exley C
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- Adult, Child, Child, Preschool, Female, Health Promotion, Health Status Disparities, Humans, Interviews as Topic, Middle Aged, Qualitative Research, State Medicine, United Kingdom, Dental Caries psychology, Health Knowledge, Attitudes, Practice, Oral Health
- Abstract
Background: Inequalities in dental decay in young children persist, resulting in high admission rates for general anaesthetics for tooth extractions. Health visitors have the potential to improve dental attendance and oral health in families least likely to engage with dental services. There is little evidence on health visitor views on this., Methods: Semi-structured interviews were conducted with a purposive sample of 17 health visitors working in both affluent and deprived areas in a single UK city. Interviews were audio recorded, transcribed, anonymized and analysed following a constructivist grounded theory approach., Results: Knowledge of oral health was high and health visitors requested oral health education specific to the communities they worked in. Health visitors reported effective, formal referral processes to other health services but not to primary NHS dental services even when dealing with infants in pain. Health visitors interviewed were largely unaware of specific NHS dental services which reduce barriers to dental care including interpreting services and dental services for children with additional needs., Conclusions: Health visitors interviewed were knowledgeable and enthusiastic about oral health but not about dental services. Inadequate links with NHS dental services may limit their effectiveness in oral health improvement and this needs to be addressed., (© The Author(s) 2018. Published by Oxford University Press on behalf of Faculty of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
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- 2019
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40. Obtaining patient feedback for quality assurance of undergraduate dental teaching.
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Freeman Z, Ellis JS, Holmes RD, Rolland SL, and Waterhouse PJ
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- Feedback, Focus Groups, Humans, Surveys and Questionnaires, Teaching, Education, Dental, Students
- Abstract
Introduction In order to achieve the educational standards of the General Dental Council, providers of UK dental education programmes are required to demonstrate that feedback from patients is collected and used to inform programme development. Aims To determine areas of undergraduate dental training programmes that patients feel able to comment upon, allowing development of a patient feedback questionnaire. Methods Patients receiving treatment from undergraduate students were recruited to focus groups (n = 5, n = 6) where their experience of receiving student care was explored. Audio transcriptions were analysed for emergent themes. These themes informed the design of a questionnaire which was presented to a further patient focus group (n = 4) for content and face validity testing. Staff (n = 4) and student (n = 8) focus groups discussed its delivery. Results Patients were able to comment upon treatment quality, safety, the student-teacher interaction, and appointment times. An 18-question questionnaire was developed to include free text comments and answers on a visual analogue scale. It was modified following focus groups with patients, staff, and students. Conclusion Patients undergoing student treatment identified aspects of the clinical teaching programme that could be included in a feedback questionnaire. Following a pilot, the questionnaire will form part of the teaching quality assurance process.
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- 2019
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41. Use of programme budgeting and marginal analysis to set priorities for local NHS dental services: learning from the north east of England.
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Holmes RD, Steele JG, Exley C, Vernazza CR, and Donaldson C
- Subjects
- Adult, Advisory Committees, Aged, Aged, 80 and over, Budgets methods, Cost-Benefit Analysis methods, Decision Making, Organizational, Dental Care economics, Dental Care methods, England, Female, Health Priorities economics, Humans, Male, Middle Aged, State Medicine economics, Young Adult, Budgets organization & administration, Dental Care organization & administration, Health Priorities organization & administration, State Medicine organization & administration
- Abstract
Background: Priority setting is necessary where competing demands exceed the finite resources available. The aim of the study was to develop and test a prioritization framework based upon programme budgeting and marginal analysis (PBMA) as a tool to assist National Health Service (NHS) commissioners in their management of resources for local NHS dental services., Methods: Twenty-seven stakeholders (5 dentists, 8 commissioners and 14 patients) participated in a case-study based in a former NHS commissioning organization in the north of England. Stakeholders modified local decision-making criteria and applied them to a number of different scenarios., Results: The majority of financial resources for NHS dental services in the commissioning organization studied were allocated to primary care dental practitioners' contracts in perpetuity, potentially constraining commissioners' abilities to shift resources. Compiling the programme budget was successful, but organizational flux and difficulties engaging local NHS commissioners significantly impacted upon the marginal analysis phase., Conclusions: NHS dental practitioners' contracts resemble budget-silos which do not facilitate local resource reallocation. 'Context-specific' factors significantly challenged the successful implementation and impact of PBMA. A local PBMA champion embedded within commissioning organizations should be considered. Participants found visual depiction of the cost-value ratio helpful during their initial priority setting deliberations.
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- 2018
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42. Resource allocation in NHS dentistry: recognition of societal preferences (RAINDROP): study protocol.
- Author
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Vernazza CR, Carr K, Wildman J, Gray J, Holmes RD, Exley C, Smith RA, and Donaldson C
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- Adult, Delivery of Health Care standards, Dental Health Services economics, England, Evidence-Based Practice, Health Care Rationing, Humans, Qualitative Research, Delivery of Health Care organization & administration, Dental Health Services organization & administration, Resource Allocation economics, Resource Allocation organization & administration, State Medicine
- Abstract
Background: Resources in any healthcare systems are scarce relative to need and therefore choices need to be made which often involve difficult decisions about the best allocation of these resources. One pragmatic and robust tool to aid resource allocation is Programme Budgeting and Marginal Analysis (PBMA), but there is mixed evidence on its uptake and effectiveness. Furthermore, there is also no evidence on the incorporation of the preferences of a large and representative sample of the general public into such a process. The study therefore aims to undertake, evaluate and refine a PBMA process within the exemplar of NHS dentistry in England whilst also using an established methodology (Willingness to Pay (WTP)) to systematically gather views from a representative sample of the public., Methods: Stakeholders including service buyers (commissioners), dentists, dental public health representatives and patient representatives will be recruited to participate in a PBMA process involving defining current spend, agreeing criteria to judge services/interventions, defining areas for investment and disinvestment, rating these areas against the criteria and making final recommendations. The process will be refined based on participatory action research principles and evaluated through semi-structured interviews, focus groups and observation of the process by the research team. In parallel a representative sample of English adults will be recruited to complete a series of four surveys including WTP valuations of programmes being considered by the PBMA panel. In addition a methodological experiment comparing two ways of eliciting WTP will be undertaken., Discussion: The project will allow the PBMA process and particularly the use of WTP within it to be investigated and developed. There will be challenges around engagement with the task by the panel undertaking it and with the outputs by stakeholders but careful relationship building will help to mitigate this. The large volume of data will be managed through careful segmenting of the analysis and the use of the well-established Framework approach to qualitative data analysis. WTP has various potential biases but the elicitation will be carefully designed to minimise these and some methodological investigation will take place.
- Published
- 2018
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43. The use of drama within midwifery education to facilitate the understanding of professional behaviour and values.
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Lawrence J and Wier J
- Subjects
- Adult, Curriculum standards, Female, Humans, Interprofessional Relations, Pregnancy, Problem-Based Learning, Professional Practice trends, Students, Nursing psychology, Drama, Midwifery education, Professional Practice standards, Social Values, Teaching standards
- Abstract
Objective: to develop student midwife understanding of professional values and the application of these in clinical practice, prior to commencing their first clinical placement., Design: an action research project., Setting: a Simulation Suite environment within a University setting., Participants: 6 year 3 drama students and a cohort of 36 midwifery students., Findings: the students were supportive of the idea of collaborative projects as this permitted the facilitation of student understanding of key professional values and their application in the clinical setting., Key Conclusions: the students felt that the move away from a didactic approach to learning and teaching towards a more experiential model of teaching, enabled a more in depth reflection on the importance of professional standards and behaviour when providing care to pregnant women., (Copyright © 2018 Elsevier Ltd. All rights reserved.)
- Published
- 2018
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44. Insufficient evidence for the role of school dental screening in improving oral health.
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Holmes RD
- Subjects
- Humans, United States, Health Education, Dental, Oral Health
- Abstract
Data sourcesThe Cochrane Oral Health's Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), Medline, Embase, the US National Institutes of Health Trials Registry (ClinicalTrials.gov) and the World Health Organization International Clinical Trials Registry Platform databases.Study selectionRandomised controlled trials (cluster or parallel) evaluating school dental screening compared with no intervention or with one type of screening compared with another were included.Data extraction and synthesisTwo reviewers independently abstracted data and assessed risk of bias. Risk ratios were calculated for dichotomous outcomes, with data being pooled where appropriate. The GRADE approach was used to interpret findings.ResultsSix trials involving 19,498 children were included. Two were considered to be at low risk of bias, three at unclear risk and one at high risk. No conclusions could be made from four studies comparing traditional screening versus no screening because the evidence was inconsistent. Two trials evaluating criteria-based screening versus no screening suggested a possible benefit; RR = 1.07 (95% CI; 0.99-1.16). No difference was found when comparing criteria-based screening with traditional screening, RR = 1.01, (95% CI; 0.94-1.08). No trials reported on long-term follow-up or cost-effectiveness and adverse events.ConclusionsThe trials included in this review evaluated short-term effects of screening, assessing follow-up periods of three to eight months. We found very low certainty evidence that was insufficient to allow us to draw conclusions about whether there is a role for traditional school dental screening in improving dental attendance. For criteria-based screening, we found low-certainty evidence that it may improve dental attendance when compared to no screening. However, when compared to traditional screening there was no evidence of a difference in dental attendance (very low-certainty evidence).We found low-certainty evidence to conclude that personalised or specific referral letters improve dental attendance when compared to non-specific counterparts. We also found low-certainty evidence that screening supplemented with motivation (oral health education and offer of free treatment) improves dental attendance in comparison to screening alone.We did not find any trials addressing cost-effectiveness and adverse effects of school dental screening.
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- 2018
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45. Experiences of service users involved in recruitment for nursing courses: A phenomenological research study.
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Stevens K, Bernal C, Devis K, and Southgate A
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- Community Participation methods, Feedback, Focus Groups, Humans, Students, Nursing psychology, Community Participation psychology, Education, Nursing, Baccalaureate methods, Personnel Selection methods
- Abstract
The aim of this study was to gain insight into service users' experiences of participating in recruitment for Adult, Mental Health and Child nursing studies at the authors' university; to establish potential motivations behind such participation; and to make suggestions for improved future practice. The involvement of service users in nurse education and recruitment has for some years been required by the Nursing and Midwifery Council, but there is a dearth of publications on the meaning of that involvement to participating service users. It is hoped that this study will contribute to this body of knowledge. A phenomenological approach was selected, field-specific focus groups of service users being facilitated using a semi-structured interview format; these were audio recorded and transcribed. The data was analysed using thematic analysis. Participation was subject to the service users having been involved in recruitment to nursing studies at the authors' university and the focus groups took place either at the university or at the child participants' school. Themes identified demonstrated largely positive experiences and a sense of meaningful involvement for all concerned. Findings indicated a close link between the values of the participants and those of the wider NHS, benefits to a sense of wellbeing and achievement, as well as the need for greater ownership of the recruitment process by service users. Potential lessons for academics wishing to promote greater service user involvement in student recruitment are articulated., (Copyright © 2017 Elsevier Ltd. All rights reserved.)
- Published
- 2017
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46. Tooth brushing frequency and risk of new carious lesions.
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Holmes RD
- Subjects
- Evidence-Based Dentistry, Humans, Incidence, Risk Factors, Dental Caries epidemiology, Dental Caries prevention & control, Toothbrushing statistics & numerical data
- Abstract
Data sourcesMedline, Embase, CINHAL and the Cochrane databases.Study selectionTwo reviewers selected studies, and case-control, prospective cohort, retrospective cohort and experimental trials evaluating the effect of toothbrushing frequency on the incidence or increment of new carious lesions were considered.Data extraction and synthesisTwo reviewers undertook data abstraction independently using pre-piloted forms. Study quality was assessed using a quality assessment tool for quantitative studies developed by the Effective Public Health Practice Project (EPHPP). Meta-analysis of caries outcomes was carried out using RefMan and meta-regressions undertaken to assess the influence of sample size, follow-up period, caries diagnosis level and study methodological quality.ResultsThirty-three studies were included of which 13 were considered to be methodologically strong, 14 moderate and six weak. Twenty-five studies contributed to the quantitative analysis. Compared with frequent brushers, self-reported infrequent brushers demonstrated a higher incidence of carious lesions, OR=1.50 (95%CI: 1.34 -1.69). The odds of having carious lesions differed little when subgroup analysis was conducted to compare the incidence between ≥2 times/d vs <2 times/d; OR=1.45; (95%CI; 1.21 - 1.74) and ≥1 time/d vs <1 time/d brushers OR=1.56; (95%CI; 1.37 - 1.78). Brushing <2 times/day significantly caused an increment of carious lesions compared with ≥2/day brushing, standardised mean difference [SMD] =0.34; (95%CI; 0.18 - 0.49). Overall, infrequent brushing was associated with an increment of carious lesions, SMD= 0.28; (95%CI; 0.13 - 0.44). Meta-analysis conducted with the type of dentition as subgroups found the effect of infrequent brushing on incidence and increment of carious lesions was higher in deciduous, OR=1.75; (95%CI; 1.49 - 2.06) than permanent dentition OR=1.39; (95% CI: 1.29 -1.49). Meta-regression indicated that none of the included variables influenced the effect estimate.ConclusionsIndividuals who state that they brush their teeth infrequently are at greater risk for the incidence or increment of new carious lesions than those brushing more frequently. The effect is more pronounced in the deciduous than in the permanent dentition. A few studies indicate that this effect is independent of the presence of fluoride in toothpaste.
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- 2016
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47. Mechanisms of the placebo effect in pain and psychiatric disorders.
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Holmes RD, Tiwari AK, and Kennedy JL
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- Animals, Anxiety Disorders drug therapy, Anxiety Disorders genetics, Anxiety Disorders physiopathology, Depression drug therapy, Depression genetics, Depression physiopathology, Genotype, Humans, Pain drug therapy, Pain genetics, Pain physiopathology, Pharmacogenetics methods, Pharmacogenomic Variants, Phenotype, Schizophrenia drug therapy, Schizophrenia genetics, Schizophrenia physiopathology, Anxiety Disorders psychology, Controlled Clinical Trials as Topic methods, Depression psychology, Pain psychology, Placebo Effect, Placebos, Schizophrenic Psychology
- Abstract
Placebo effect research over the past 15 years has improved our understanding of how placebo treatments reduce patient symptoms. The expectation of symptom improvement is the primary factor underlying the placebo effect. Such expectations are shaped by past experiences, contextual cues and biological traits, which ultimately modulate one's degree of response to a placebo. The body of evidence that describes the physiology of the placebo effect has been derived from mechanistic studies primarily restricted to the setting of pain. Imaging findings support the role of endogenous opioid and dopaminergic networks in placebo analgesia in both healthy patients as well as patients with painful medical conditions. In patients with psychiatric illnesses such as anxiety disorders or depression, a vast overlap in neurological changes is observed in drug responders and placebo responders supporting the role of serotonergic networks in placebo response. Molecular techniques have been relatively underutilized in understanding the placebo effect until recently. We present an overview of the placebo responder phenotypes and genetic markers that have been associated with the placebo effect in pain, schizophrenia, anxiety disorders and depression.
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- 2016
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48. Patterns of care and service use amongst children in England, Wales and Northern Ireland 2013.
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Holmes RD, Porter J, Devapal L, and White DA
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- Adolescent, Child, England, Female, Humans, Male, Northern Ireland, Wales, Dental Health Services statistics & numerical data, Dental Health Surveys, Oral Health
- Abstract
Background The 2013 Children's Dental Health survey is the fifth in a series of national surveys.Aims This paper describes children's reported use of dental services, their experience of receiving dental treatment and parental satisfaction with services.Methodology A representative sample of children (aged 5, 8, 12 and 15 years) in England, Wales and Northern Ireland were invited to participate in dental examinations. Older children and all parents were invited to complete a questionnaire about oral health behaviours and attitudes.Results Over 80% of 12- and 15-year-olds reported attending for a check-up. According to parents, 9 in 10 children of all ages had visited a dentist in the last year and 9 in 10 parents reported they were satisfied with the last dental practice their child had visited. There was some variation by country with respect to children's experiences of fillings and extractions.Conclusions There has been little change in the reported attendance patterns of children since the 2003 survey. Family deprivation (measured by children's eligibility for free school meals) negatively influenced dental attendance for regular check-ups, attendance within the last 12 months and the likelihood of having experienced difficulties accessing NHS dental services for children.
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- 2016
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49. Urolithiasis following urinary diversion.
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Seth JH, Promponas J, Hadjipavlou M, Anjum F, and Sriprasad S
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- Cystectomy, Humans, Risk Factors, Postoperative Complications etiology, Urinary Diversion adverse effects, Urolithiasis etiology
- Abstract
Urolithiasis is a well-known occurrence after cystectomy and urinary diversion. With high incidence and recurrence rates of urolithiasis, complex anatomy and associated morbidities, these patients remain a management challenge for urologists. The purpose of this review is to examine the literature and consider the risk factors for stone formation in this group of patients and reflect on the reported outcomes with the range of available treatment options.
- Published
- 2016
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50. Psychology of behaviour change is key to effective oral health promotion.
- Author
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Holmes RD
- Subjects
- Humans, Pilot Projects, Health Promotion, Qualitative Research
- Abstract
Data sourcesAMED, CINAHL, Cochrane Library, Embase, Medline, PsycINFO, PsycARTICLES, ScienceDirect, SocINDEX, ASSIA, Social Policy and Practice, HMIC (Health Management Information Consortium), The Knowledge Network, Intute, MedNar, Copac, EPPI-Centre, EThOS, OpenGrey and TRIP databases. Searches were limited to publications in the English language published after 1994.Study selectionStudies set in general practice that investigated promoting good oral health in adult or child patients were considered. Study quality was assessed using NICE public health guidance checklists.Data extraction and synthesisStudies were grouped according to the evidence they offered in relation to the research questions and key findings and themes identified. No meta-analysis was conducted. Qualitative studies underwent thematic analysis. The evidence was synthesised after considering the studies' homogeneity, quality and applicability and studying the evidence tables.ResultsForty-four studies reported in 52 papers were considered. Fifteen studies were randomised controlled trials (RCTs), two cluster RCTs and one controlled trial. Five quasi-experimental studies, two before and after studies without controls, three surveys, 11 qualitative studies, three mixed methods studies, one audit and one pilot study were included.The studies were very heterogeneous; the quality of reporting highly variable with many using patient reported behaviours rather than objective measures. Follow-up periods were also short. Narrative summaries of psychological and behavioural models, verbal advice, written advice, other methods of conveying advice, message content, sender characteristics, receiver factors, 'framing' of advice, barriers and facilitators and patient satisfaction were provided.ConclusionsThe results of this review suggest that the psychology of behaviour change is the key to oral health promotion, and greater emphasis on teaching oral health professionals about health psychology would make oral health promotion in the dental surgery more effective.
- Published
- 2016
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