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130 results on '"Hong, Kyung-Wook"'

1. SARS-CoV-2 infection exacerbates the cellular pathology of Parkinson’s disease in human dopaminergic neurons and a mouse model

Author

Lee, Bina, Choi, Ha Nyeoung, Che, Young Hyun, Ko, Myungjun, Seong, Hye Min, Jo, Min Gi, Kim, Seon-Hee, Song, Chieun, Yoon, Subeen, Choi, Jiwoo, Kim, Jeong Hee, Kim, Minkyeong, Lee, Min Young, Park, Sang Won, Kim, Hye Jung, Kim, Seong Jae, Moon, Do Sik, Lee, Sun, Park, Jae-Hoon, Yeo, Seung-Geun, Everson, Richard G., Kim, Young Jin, Hong, Kyung-Wook, Roh, In-Soon, Lyoo, Kwang-Soo, Kim, Yong Jun, and Yun, Seung Pil

Published
2024
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3. Relationship between the appropriateness of antibiotic treatment and clinical outcomes/medical costs of patients with community-acquired acute pyelonephritis: a multicenter prospective cohort study

Author

Yoon, Choseok, Park, Se Yoon, Kim, Bongyoung, Kwon, Ki Tae, Ryu, Seong-yeol, Wie, Seong-Heon, Jo, Hyun-uk, Kim, Jieun, Hong, Kyung-Wook, Kim, Hye In, Kim, Hyun ah, Kim, Mi-Hee, Bae, Mi-Hyun, Sohn, Yong-Hak, Kim, Jieun, Lee, Yangsoon, and Pai, Hyunjoo

Published
2022
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15. Additional file 1 of Relationship between the appropriateness of antibiotic treatment and clinical outcomes/medical costs of patients with community-acquired acute pyelonephritis: a multicenter prospective cohort study

Author

Yoon, Choseok, Park, Se Yoon, Kim, Bongyoung, Kwon, Ki Tae, Ryu, Seong-yeol, Wie, Seong-Heon, Jo, Hyun-uk, Kim, Jieun, Hong, Kyung-Wook, Kim, Hye In, Kim, Hyun ah, Kim, Mi-Hee, Bae, Mi-Hyun, Sohn, Yong-Hak, Lee, Yangsoon, and Pai, Hyunjoo

Abstract

Additional file 1: Table S1. Clinical outcomes and medical costs of community-acquired acute pyelonephritis according to the appropriateness of antibiotic use: before propensity-score matching.

Published
2022
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17. Maternal and Neonatal Outcomes in Pregnant Women With Coronavirus Disease 2019

Author

Chung, Youseung, primary, Kim, Eun Jin, additional, Kim, Hee-Sung, additional, Park, Kyung-Hwa, additional, Baek, Ji Hyeon, additional, Kim, Jungok, additional, Lee, Ji Yeon, additional, Lee, Chang-Seop, additional, Lim, Seungjin, additional, Kim, Shin-Woo, additional, Kim, Eu Suk, additional, Shi, Hye Jin, additional, Hong, Shin Hee, additional, Jun, Jae-Bum, additional, Hong, Kyung-Wook, additional, Choi, Jae-Phil, additional, Kim, Jinyeong, additional, Yang, Kyung Sook, additional, and Yoon, Young Kyung, additional

Published
2022
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19. Relationship Between The Appropriateness of Antibiotic Treatment and Clinical Outcomes of Patients With Community-Acquired Acute Pyelonephritis: A Multicenter Prospective Cohort Study

Author

Yoon, Choseok, primary, Park, Se Yoon, additional, Kim, Bongyoung, additional, Kwon, Ki Tae, additional, Ryu, Seong-yeol, additional, Wie, Seong-Heon, additional, Jo, Hyun-uk, additional, Kim, Jieun, additional, Hong, Kyung-Wook, additional, Kim, Hye In, additional, Kim, Hyun ah, additional, Kim, Mi-Hee, additional, Bae, Mi-Hyun, additional, Sohn, Yong-Hak, additional, Lee, Yangsoon, additional, and Pai, Hyunjoo, additional

Published
2021
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20. Differences in the Clinical Outcome of Community-Acquired APN According to the Appropriateness of Antibiotic Use

Author

Kim, Bongyoung, primary, Yoon, Choseok, additional, Park, Se Yoon, additional, Kwon, Ki Tae, additional, Ryu, Seong-yeol, additional, Wie, Seong-Heon, additional, Jo, Hyun-uk, additional, Kim, Jieun, additional, Hong, Kyung-Wook, additional, In Kim, Hye, additional, Kim, Hyun ah, additional, Kim, Mi-Hee, additional, Bae, Mi-Hyun, additional, Sohn, Yong-Hak, additional, Lee, Yangsoon, additional, and Pai, Hyunjoo, additional

Published
2021
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21. Clinical Features of Adult COVID-19 Patients without Risk Factors before and after the Nationwide SARS-CoV-2 B.1.617.2 (Delta)-variant Outbreak in Korea: Experience from Gyeongsangnam-do

Author

Ryu, Byung-Han, primary, Hong, Sun In, additional, Lim, Su Jin, additional, Cho, Younghwa, additional, Hwang, Cheolgu, additional, Kang, Hyungseok, additional, Kim, Si-Ho, additional, Wi, Yu Mi, additional, Hong, Kyung-Wook, additional, Bae, In-Gyu, additional, and Cho, Oh-Hyun, additional

Published
2021
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22. 1667. Change in characteristics of community-onset ciprofloxacin-resistant E. coli isolates causing community-acquired acute pyelonephritis in South Korea

Author

Kim, Bongyoung, primary, Kwon, Ki Tae, additional, Ryu, Seong-yeol, additional, Wie, Seong-Heon, additional, Jo, Hyun-uk, additional, Kim, Jieun, additional, Park, Se Yoon, additional, Hong, Kyung-Wook, additional, Kim, Hye In, additional, Kim, Hyun ah, additional, Kim, Mi-Hee, additional, Bae, Mi-Hyun, additional, Sohn, Yong-Hak, additional, Lee, Yangsoon, additional, and Pai, Hyunjoo, additional

Published
2020
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23. Changes in Clinical Characteristics of Community-Acquired Acute Pyelonephritis and Antimicrobial Resistance of Uropathogenic Escherichia coli in South Korea in the Past Decade

Author

Kwon, Ki Tae, primary, Kim, Bongyoung, additional, Ryu, Seong-yeol, additional, Wie, Seong-Heon, additional, Kim, Jieun, additional, Jo, Hyun-uk, additional, Park, Se Yoon, additional, Hong, Kyung-Wook, additional, Kim, Hye In, additional, Kim, Hyun ah, additional, Kim, Mi-Hee, additional, Bae, Mi Hyun, additional, Sohn, Yong-Hak, additional, Lee, Yangsoon, additional, and Pai, Hyunjoo, additional

Published
2020
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24. Clinical impact of early reinsertion of a central venous catheter after catheter removal in patients with catheter-related bloodstream infections

Author

Lee, Yu-Mi, primary, Ryu, Byung-Han, additional, Hong, Sun In, additional, Cho, Oh-Hyun, additional, Hong, Kyung-Wook, additional, Bae, In-Gyu, additional, Kwack, Won Gun, additional, Kim, Young Jin, additional, Chung, Eun Kyoung, additional, Kim, Dong Youn, additional, Lee, Mi Suk, additional, and Park, Ki-Ho, additional

Published
2020
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25. Changes in the characteristics of community-onset fluoroquinolone-resistant Escherichia coliisolates causing community-acquired acute pyelonephritis in South Korea

Author

Kim, Bongyoung, Kim, Jeoungyeon, Jo, Hyun-uk, Kwon, Ki Tae, Ryu, Seong-yeol, Wie, Seong-Heon, Kim, Jieun, Park, Se Yoon, Hong, Kyung-Wook, Kim, Hye In, Kim, Hyun ah, Kim, Mi-Hee, Bae, Mi Hyun, Sohn, Yong-Hak, Kim, Jieun, Lee, Yangsoon, and Pai, Hyunjoo

Abstract

This study aimed to examine the changes in the characteristics of community-onset fluoroquinolone-resistant (FQ-R) Escherichia coliisolates causing community-acquired acute pyelonephritis (APN) in South Korea.

Published
2022
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31. 1451. Change in Clinical Characteristics of Community-Acquired Acute Pyelonephritis in South Korea: Comparison Between 2010–2011 and 2017–2018

Author

Tae Kwon, Ki, Ryu, Seong-yeol, Wie, Seong-Heon, Jo, Hyun-uk, Yoon Park, Se, Hong, Kyung-Wook, In Kim, Hye, ah Kim, Hyun, Kim, Mi-Hee, Bae, Mi-Hyun, Sohn, Yong-Hak, Kim, Jieun, Lee, Yangsoon, Kim, Bongyoung, and Pai, Hyunjoo

Subjects
Abstracts, Poster Abstracts
Abstract

Background The aim of this study was to examine the change in clinical characteristics of community-acquired acute pyelonephritis (CA-APN) in South Korea between 2010–2011 and 2017–2018. Methods We recruited all CA-APN patients with age ≥19 years who visited 4 hospitals in South Korea from September 2017 to August 2018, prospectively. The inclusion criteria were: (i) presence of fever (body temperature ≥37.8°C), (ii) pyuria [≥5–9 white blood cells per high power field (WBC/HPF)], and (iii) clinical symptoms or signs relevant to APN. Patients diagnosed with APN more than 48 hours after admission, those transferred from other hospitals during treatment of APN, those with other reasons for fever and pyuria, and those with insufficient data were excluded. Each patient was included for the first episode during the study period. The collected data were compared with those from the previous study with the same design in 2010–2012, in which the same hospitals were participated. Results A total of 349 and 472 patients were recruited during 2017–2018 and 2010–2011, respectively. E. coli was the most common causative pathogen for CA-APN in both periods (87.5% vs. 86.6%, P = 0.727). Significantly higher antimicrobial resistance against fluoroquinolone (33.5% vs. 21.0%, P = 0.001), cefotaxime (34.8% vs. 7.6%, P P = 0.040) were observed for E. coli isolates in 2017–2018 compared with those in 2010–2011. The patients in 2017–2018 were older (60.71±17.29 vs. 55.77±18.60, P

Published
2019

33. Distinct molecular evolution of influenza H3N2 strains in the 2016/17 season and its implications for vaccine effectiveness

Author

Kim, Jin Il, primary, Park, Sehee, additional, Chu, Hyuk, additional, Lee, Ilseob, additional, Bae, Joon-Yong, additional, Yoo, Kirim, additional, Kim, Juwon, additional, Lee, Joo-Yeon, additional, Lee, Namju, additional, Kim, Miseon, additional, Kim, Jun-Sub, additional, Hong, Kyung Wook, additional, Jun, Kyung Ran, additional, Lee, Jeong Nyeo, additional, Kim, Kisoon, additional, and Park, Man-Seong, additional

Published
2019
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34. Response System for and Epidemiological Features of COVID-19 in Gyeongsangnam-do Province in South Korea.

Author

Wi, Yu Mi, Lim, Su Jin, Kim, Si-Ho, Lim, Seungjin, Lee, Su Jin, Ryu, Byung-Han, Hong, Sun In, Cho, Oh-Hyun, Moon, Kyunglan, Hong, Kyung-Wook, Kim, Sunjoo, and Bae, In-Gyu

Subjects
AGEUSIA, EMERGENCY management, HEALTH care rationing, ISOLATION (Hospital care), COVID-19 testing, QUARANTINE, SMELL disorders, SEVERITY of illness index, CONTACT tracing, EARLY diagnosis, DESCRIPTIVE statistics, COVID-19
Abstract

Background The South Korean government has been combating the coronavirus disease 2019 (COVID-19) outbreak using public information and extensive viral screening. We describe the application of the Korean response system in Gyeongsangnam-do province and outline the epidemiological features of COVID-19 in the cohort. Methods A Rapid Response Team tracked the patients' activities and identified close contacts. A Patient Management Team made decisions regarding the severity of illness, hospital allocation depending on severity, and time of discharge. A national medical center with 155 beds and 4 university-affiliated hospitals with 48 negative-pressure isolation rooms were dedicated for patients with COVID-19. Results As of 15 April, 17 400 residents were tested, of whom 111 were confirmed positive cases. Of the 111 patients, 78 were cured and discharged, 2 recovered after mechanical ventilation, and none died. One healthcare worker at the national center tested positive for SARS-CoV-2. All 412 staff members at the center were tested, but there were no additional infections. Cough (30.0%) was the most common initial symptom, whereas anosmia and ageusia were the first symptoms in 14.7% and 15.7% of the patients, respectively. Overall, 25 patients (22.5%) reported having no symptoms at admission and 7 (6.3%) remained asymptomatic at discharge. Conclusions A response system that enabled the early detection of COVID-19 cases, including asymptomatic and presymptomatic cases, and timely quarantine of these patients and their contacts, along with efficient allocation of medical resources, was the key to curbing the COVID-19 outbreak in Gyeongsangnam-do Province. [ABSTRACT FROM AUTHOR]

Published
2021
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35. Effects of subinhibitory concentrations of chlorhexidine and mupirocin on biofilm formation in clinical meticillin-resistant Staphylococcus aureus.

Author

Park, K.-H., Jung, M., Kim, D.Y., Lee, Y.-M., Lee, M.S., Ryu, B.-H., Hong, S.I., Hong, K.-W., Bae, I.-G., Cho, O.-H., Park, Ki-Ho, Jung, Minji, Kim, Dong Youn, Lee, Yu-Mi, Lee, Mi Suk, Ryu, Byung-Han, Hong, Sun In, Hong, Kyung-Wook, Bae, In-Gyu, and Cho, Oh-Hyun

Abstract

Background: The effects of subinhibitory concentrations (sub-MICs) of antibacterial agents on the biofilm-forming ability of Staphylococcus aureus require further study.Aim: To investigate the effects of sub-MICs of chlorhexidine and mupirocin on biofilm formation in clinical meticillin-resistant Staphylococcus aureus (MRSA) isolates.Methods: MRSA isolates were collected from patients with bloodstream infections at a tertiary care hospital. The basal level of biofilm formation and biofilm induction by sub-MICs of chlorhexidine and mupirocin were evaluated by measuring biofilm mass stained with Crystal Violet.Findings: Of the 112 MRSA isolates tested, 63 (56.3%) and 44 (39.3%) belonged to sequence type (ST)5 and ST72 lineages, respectively, which are the predominant healthcare- and community-associated clones in South Korea. ST5 isolates were more likely to have chlorhexidine MIC ≥4 (73.0% vs 29.5%), resistance to mupirocin (23.8% vs 0%), agr dysfunction (73.0% vs 9.1%), and qacA/B gene (58.7% vs 2.3%) compared to ST72 isolates. The basal level of biofilm formation ability was frequently stronger in ST72 isolates compared to ST5 isolates (77.3% vs 12.7%). Sub-MICs of chlorhexidine and mupirocin promoted biofilm formation in 56.3% and 53.6%, respectively, of all isolates. Biofilm induction was more prevalent in ST5 isolates (85.7% for chlorhexidine, 69.8% for mupirocin) than in ST72 isolates (15.9% for chlorhexidine, 27.3% for mupirocin).Conclusion: Sub-MICs of chlorhexidine and mupirocin promoted biofilm formation in half of the clinical MRSA isolates. Our results suggest that ST5 MRSA biofilm can be induced together with some other bacterial virulent factors following exposure to chlorhexidine, which might confer a survival advantage to this clone in the healthcare environment. [ABSTRACT FROM AUTHOR]

Published
2020
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36. Clinical impact of early reinsertion of a central venous catheter after catheter removal in patients with catheter-related bloodstream infections

Author

Lee, Yu-Mi, Ryu, Byung-Han, Hong, Sun In, Cho, Oh-Hyun, Hong, Kyung-Wook, Bae, In-Gyu, Kwack, Won Gun, Kim, Young Jin, Chung, Eun Kyoung, Kim, Dong Youn, Lee, Mi Suk, and Park, Ki-Ho

Abstract

AbstractObjective:Early replacement of a new central venous catheter (CVC) may pose a risk of persistent or recurrent infection in patients with a catheter-related bloodstream infection (CRBSI). We evaluated the clinical impact of early CVC reinsertion after catheter removal in patients with CRBSIs.Methods:We conducted a retrospective chart review of adult patients with confirmed CRBSIs in 2 tertiary-care hospitals over a 7-year period.Results:To treat their infections, 316 patients with CRBSIs underwent CVC removal. Among them, 130 (41.1%) underwent early CVC reinsertion (≤3 days after CVC removal), 39 (12.4%) underwent delayed reinsertion (>3 days), and 147 (46.5%) did not undergo CVC reinsertion. There were no differences in baseline characteristics among the 3 groups, except for nontunneled CVC, presence of septic shock, and reason for CVC reinsertion. The rate of persistent CRBSI in the early CVC reinsertion group (22.3%) was higher than that in the no CVC reinsertion group (7.5%; P= .002) but was similar to that in the delayed CVC reinsertion group (17.9%; P> .99). The other clinical outcomes did not differ among the 3 groups, including rates of 30-day mortality, complicated infection, and recurrence. After controlling for several confounding factors, early CVC reinsertion was not significantly associated with persistent CRBSI (OR, 1.59; P= .35) or 30-day mortality compared with delayed CVC reinsertion (OR, 0.81; P= .68).Conclusions:Early CVC reinsertion in the setting of CRBSI may be safe. Replacement of a new CVC should not be delayed in patients who still require a CVC for ongoing management.

Published
2021
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37. Phylogenetic relationships of the HA and NA genes between vaccine and seasonal influenza A(H3N2) strains in Korea

Author

Kim, Jin Il, primary, Lee, Ilseob, additional, Park, Sehee, additional, Bae, Joon-Yong, additional, Yoo, Kirim, additional, Cheong, Hee Jin, additional, Noh, Ji Yun, additional, Hong, Kyung Wook, additional, Lemey, Philippe, additional, Vrancken, Bram, additional, Kim, Juwon, additional, Nam, Misun, additional, Yun, Soo-Hyeon, additional, Cho, Woo In, additional, Song, Joon Young, additional, Kim, Woo Joo, additional, Park, Mee Sook, additional, Song, Jin-Won, additional, Kee, Sun-Ho, additional, Song, Ki-Joon, additional, and Park, Man-Seong, additional

Published
2017
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38. Lower Respiratory Tract Diseases Caused by Common Respiratory Viruses among Stem Cell Transplantation Recipients: A Single Center Experience in Korea

Author

Hong, Kyung-Wook, primary, Choi, Su-Mi, additional, Lee, Dong-Gun, additional, Cho, Sung-Yeon, additional, Lee, Hyo-Jin, additional, Choi, Jae-Ki, additional, Kim, Si-Hyun, additional, Park, Sun Hee, additional, Choi, Jung-Hyun, additional, Yoo, Jin-Hong, additional, and Lee, Jong-Wook, additional

Published
2017
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39. TOE BERM DESIGN FOR RUBBLE-MOUND BREAKWATERS: EXAMPLE OF THE SAFI POWER PLANT PROJECT

Author

Coutosthevenot Marie and Hong Kyung-Wook

Subjects
Engineering, Berm, business.industry, Hydraulics, Outfall, law.invention, Current (stream), Waves and shallow water, law, Breakwater, Trench, General Earth and Planetary Sciences, Caisson, Geotechnical engineering, business, General Environmental Science
Abstract

DAEWOO E&C (Engineering & Construction) is in charge constructing a new 1320 MW coal-fired power plant located approximately 15 km south-west of the city of Safi in Morocco. ARTELIA Eau & Environnement was appointed by the Contractor to perform the hydraulic design review of the rubble-mound breakwaters protecting the intake and outfall. The toe berm is a key design feature of rubble-mound breakwaters built in breaking conditions, since it helps to support the armour layer and protect the structure from potential scour-induced damage. The initial toe berm design was based on Van Der Meer’s empirical formula (1998). Due to the very shallow water conditions, the toe design was verified through physical model tests (2D and 3D) in ARTELIA’s hydraulics laboratory located in Pont-de-Claix, near Grenoble (France). The physical model tests demonstrated that the toe berm (6t rocks, 3:1 slope) was not stable at key singular locations, namely roundheads and roots, where direct impacts of breaking waves caused severe damage. Given the site conditions and the construction methods, the usual solutions consisting in increasing the rock size and/or placing the toe berm in a trench had to be ruled out. It was hence decided to reinforce the toe with artificial blocks and to use rectangular concrete blocks with holes. These blocks reduced the anti-stabilizing pressure difference between the top and bottom of the blocks (Tanimoto et al., 1996) and drag force due to the considerable current. They are more usually used at the toe of vertical caissons.

Published
2017

40. HIV-associated neurocognitive disorder in HIV-infected Koreans: Korean NeuroAIDS Project

Author

Ku, Nam Su, Lee, Youngjoon, Ahn, Jin Young, Song, Je Eun, Kim, Min Hyung, Kim, Sun Bean, Jeong, Su Jin, Hong, Kyung-Wook, Kim, Eosu, Han, Sang Hoon, Song, Joon Young, Cheong, Hee Jin, Song, Young Goo, Kim, Woo Joo, Kim, June Myung, Smith, Davey M., and Choi, Jun Yong

Subjects
Adult, Male, AIDS Dementia Complex, Middle Aged, Neuropsychological Tests, Sensitivity and Specificity, Article, Young Adult, Risk Factors, Republic of Korea, Prevalence, Humans, Mass Screening, Female, Hospitals, Teaching, Aged
Abstract

HIV-associated neurocognitive disorder (HAND) is an independent predictor of early mortality and is associated with many difficulties in activities of daily living. We sought to determine the prevalence of and risk factors for HAND in HIV-infected Koreans. In addition, we investigated the performance of screening tools and components of neuropsychological (NP) tests for diagnosing HAND.HIV-infected patients were enrolled consecutively from two different urban teaching hospitals in Seoul, South Korea between March 2012 and September 2012. Participants completed a detailed NP assessment of six cognitive domains commonly affected by HIV. The Frascati criteria were used for diagnosing HAND. Four key questions, the International HIV Dementia Scale (IHDS) and Montreal Cognitive Assessment (MoCA)-K were also assessed as potential tools for screening for HAND.Among the 194 participants, the prevalence of HAND was 26.3%. Asymptomatic neurocognitive impairment and minor neurocognitive disorder accounted for 52.9 and 47.1% of the patients with HAND, respectively. In multivariate analysis, haemoglobin (Hb) level ≤ 13 g/dL (P = 0.046) and current use of a protease inhibitor-based regimen (P = 0.031) were independent risk factors for HAND. The sensitivity and specificity of the IHDS were 72.6 and 60.8%, and those of MoCA-K were 52.9 and 73.4%, respectively. The IHDS (P 0.001) and MoCA-K (P 0.001) were both useful for screening for HAND. Among NP tests, the sensitivity and specificity of the Grooved Pegboard Test were 90.2 and 72.0%, and those of the Wisconsin Card Sorting Test were 61.2 and 84.4%, respectively.HAND is a prevalent comorbidity in HIV-infected Koreans. Active screening and diagnosis with effective tools, such as the IHDS, MoCA-K and Grooved Pegboard Test, could be used to identify this important complication.

Published
2014

46. Perceptions of Tetanus-diphteria-acellular pertussis (Tdap) Vaccination among Korean Women of Childbearing Age

Author

Kim, In Seon, primary, Seo, Yu Bin, additional, Hong, Kyung-Wook, additional, Noh, Ji Yun, additional, Choi, Won Suk, additional, Song, Joon Young, additional, Cho, Geum Joon, additional, Oh, Min Jeong, additional, Kim, Hai Joong, additional, Hong, Soon Choul, additional, Sohn, Jang Wook, additional, Kim, Woo Joo, additional, and Cheong, Hee Jin, additional

Published
2013
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48. Perception on influenza vaccination in Korean women of childbearing age

Author

Kim, In Seon, primary, Seo, Yu Bin, additional, Hong, Kyung-Wook, additional, Noh, Ji Yoon, additional, Choi, Won Suk, additional, Song, Joon Young, additional, Cho, Geum Joon, additional, Oh, Min Jeong, additional, Kim, Hai Joong, additional, Hong, Soon Choul, additional, Sohn, Jang Wook, additional, Cheong, Hee Jin, additional, and Kim, Woo Joo, additional

Published
2012
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