587 results on '"Hoole, Stephen P."'
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2. Factors Associated With Coronary Angiography Performed Within 6 Months of Randomization to the Conservative Strategy in the ISCHEMIA Trial
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Pracoń, Radosław, Spertus, John A., Broderick, Samuel, Bangalore, Sripal, Rockhold, Frank W., Ruzyllo, Witold, Demchenko, Elena, Nageh, Thuraia, Grossman, Gabriel Blacher, Mavromatis, Kreton, Manjunath, Cholenahally N., Smanio, Paola E.P., Stone, Gregg W., Mancini, G.B. 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A., Oliveira, Natalia S, Lima, Rodolfo G. S. D, Figueiredo, Estevao, Edilena Paulino Azevedo, Bruna, Ricardo Caramori, Paulo, Bizzaro Santos, Marco, Germann, Amanda, Gomes, Vitor, Homem, Rosa, Magedanz, Ellen, Tumelero, Rogerio, Laimer, Rosane, Tognon, Alexandre, Dall’Orto, Frederico, Mesquita, Claudio T., Santos, Roberta P, Colafranseschi, Alexandre S., Oliveira, Amarino C., Carvalho, Luiz A., Palazzo, Isabella C., Sousa, Andre S., Eustáquio Ribeiro da Silva, Expedito, Gabriel Melo de Barros e Silva, Pedro, Yumi Okada, Mariana, de Pádua Silva Baptista, Luciana, Paula Batista, Ana, Jamus Rodrigues, Marcelo, Nogueira Rabaça, Aline, Valério Coimbra de Resende, Marcos, Francisco Saraiva, Jose, Miranda Trama, Larissa, Silva, Talita, Thais de Souza Ormundo, Camila, Vicente, Carla, Costantini, Costantino, Pinheiro, Caroline, Komar, Daniele, Szwed, Hanna, Demkow, Marcin, Kepka, Cezary, Teresinska, Anna, Walesiak, Olga, Kryczka, Karolina, Malinowska, Katarzyna, Henzel, Jan, Solecki, Mateusz, Kaczmarska, Edyta, Mazurek, Tomasz, Maksym, Jakub, Wojtera, Karolina, Fojt, Anna, Szczerba, Ewa, Drozdz, Jaroslaw, Czarniak, Bartosz, Frach, Malgorzata, Szymczyk, Konrad, Niedzwiecka, Iwona, Sobczak, Sebastian, Ciurus, Tomasz, Jakubowski, Piotr, Misztal-Teodorczyk, Magdalena, Teodorczyk, Dawid, Swiderek, Marta, Fratczak, Aleksandra, Wojtala, Ewelina, Szkopiak, Marcin, Lebioda, Patrycja, Wlodarczyk, Michal, Plachcinska, Anna, Kusmierek, Jacek, Miller, Magdalena, Marciniak, Halina, Wojtczak-Soska, Karolina, Łuczak, Katarzyna, Tarchalski, Tomasz, Cichocka-Radwan, Anna, Szwed, Hanna, Karwowski, Jaroslaw, Anna Szulczyk, Grazyna, Witkowski, Adam, Kukuła, Krzysztof, Celińska-Spodar, Małgorzta, Zalewska, Joanna, Gajos, Grzegorz, Bury, Krzysztof, Pruszczyk, Piotr, Łabyk, Andrzej, Roik, Marek, Szramowska, Agnieszka, Zdończyk, Olga, Łoboz-Grudzień, Krystyna, Jaroch, Joanna, Sokalski, Leszek, Brzezińska, Barbara, Lesiak, Maciej, Łanocha, Magdalena, Reczuch, Krzysztof W., Kolodziej, Adam, Kalarus, Zbigniew, Swiatkowski, Andrzej, Szulik, Mariola, Musial, Wlodzimierz J., Marcinkiewicz-Siemion, Marta, Bockeria, Olga, Bockeria, Leo, Bockeria, Olga, Petrosyan, Karen, Kudzoeva, Zalina, Trifonova, Tatiana, Aripova, Nodira, Chernyavskiy, Alexander M., Naryshkin, Ivan A., Kretov, Evgeniy I., Kuleshova, Alena, Grazhdankin, Igor O., Malaev, Dastan, Bershtein, Leonid L., Sayganov, Sergey A., Subbotina, Irina, Kuzmina-Krutetskaya, Anastasia M., Gumerova, Victoria, Zbyshevskaya, Elizaveta V., Katamadze, Nana O., Nikolaeva, Olga B., Kozlov, Pavel S., Kozulin, Vikentiy Y., Lubinskaya, Ekaterina I., Luis Lopez-Sendon, Jose, Castro, Almudena, Lopez-Sendon, Jose, Fernández-Figares, Virginia, Castro, Almudena, Refoyo Salicio, Elena, Guzman, Gabriela, Galeote, Gabriel, Valbuena, Silvia, Peteiro, Jesús, Dolores Martínez-Ruíz, María, Pérez-Fernández, Ruth, Blanco-Calvo, Moisés, Cuenca-Castillo, José J, Alonso-Álvarez, Encarnación, Flores-Ríos, Xacobe, García-González, Paula, Prada-Delgado, Óscar, Barge-Caballero, Gonzalo, Ramon Gonzalez Juanatey, Jose, Seijas Amigo, Jose, Souto Bayarri, Miguel, Pubull Nuñez, Virginia, Ocaranza Sanchez, Raymundo, Cid Alvarez, Belen, Peña Gil, Carlos, Martinez Monzonis, Amparo, Sionis, Alessandro, Fernández Martínez, Ana, Vila Perales, Montserrat, Maria Padró, Josep, Serra Peñaranda, Antonio, García Picart, Joan, Ginel Iglesias, Antonino, Garcia-Moll Marimon, Xavier, Pons Lladó, Guillem, Carreras Costa, Francesc, Miro, Vicente, Igual, Begoña, Diez, Jose L, Calvillo, Pilar, Ortuño, F. Marin, Valdés Chávarri, M., Quintana Giner, M., Tello Montolliu, A., Romero Aniorte, A.I., Pinar Bermudez, E., Rivera Caravaca, JM., De La Morena, G., Gracida Blancas, Montserrat, Cañavate, Olga, Guerrero, Sonia, Riera, Silvia, Enrique Castillo Luena, Jose, Enrique Castillo Luena, Jose, Lasala, Maria, Fernandez-Aviles, Francisco, Lorenzo, Maria, Sobrino, Olga, Vazquez, Alexandra, Jiang, Lixin, Chen, Jiyan, Dong, Haojian, He, Peiyu, Xia, Chunli, Yang, Junqing, Zhong, Qi, Wu, Yongjian, Tian, Yanmeng, Li, Dongze, Ma, Yitong, Li, Xiaomei, Yang, Yining, Ma, Xiang, Yu, Zixiang, Zhao, Qian, Ji, Zheng, Li, Chunguang, Zhang, Lei, Zhao, Yu, Zhu, Bolin, Yang, Xinchun, Chen, Mulei, Chi, Hongjie, Wang, Yang, Zhang, Jing, Lin, Wenhua, Jing, Rui, Liu, Jingjing, Zeng, Hesong, Zhou, Qiang, Xu, Chang, Li, Zhuxi, Li, Junhua, Xiong, Luyang, Fu, Xin, Gao, Dan, Jiang, Dengke, Leng, Ran, Wang, Xutong, Yuan, Qianqian, Zhang, Lili, Yang, Bin, Bai, Ziliang, Li, Jianhua, Qi, Jie, Wang, Fei, Wang, Haitao, Yang, 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M., Dongen, Elise van, Janzen, Elisabeth M., Niehe, Sander R., Suryapranata, Harry, Ahoud, Sandra, Vugt, Stijn van, Ramos, Ruben, Santa Marta, Hospital de, Cacela, Duarte, Santana, Ana, Fiarresga, Antonio, Sousa, Lidia, Marques, Hugo, Patricio, Lino, Selas, Mafalda, Bernanrdes, Luis, Silva, Filipa, Rio, Pedro, Freixo, Cláudia, Carvalho, Ramiro, Ferreira, Rui, Silva, Tiago, Rodrigues, Ines, Modas, Pedro, Portugal, Guilherme, Fragata, Jose, Pinto, Fausto J., Cabrita, Inês Zimbarra, Menezes, Miguel Nobre, Rocha, Andreia, Lopes, Guilhermina Cantinho, Figueiras, Francisca Patuleia, Almeida, Ana Gomes, Coelho, Andreia, CanVas Silva, Pedro, Capinha, Marta, Nobre, Angelo, Caetano, Maria Inês, Francisco, Ana Rita, Silva, Susana, Ferreira, Nuno, de Gaia, Vila Nova, Lopes, Ricardo L., Diaz, Rafael, Guzman, Luis, Tinnirello, Veronica, Figal, Julio César, Nicolás Mungo, Matías, Buenos Aires, Ciudad Autonoma de, Méndiz, Oscar, Cortés, Claudia, Favaloro, Roberto René, Alvarez, Carlos, Garcia, Marina, Blanca, Bahia, Courtis, Javier, Godoy, Valeria, Zeballos, Gabriela, Schiavi, Lilia, Actis, Maria Victoria, Rubio, Mariano, Scaro, Graciela, White, Harvey Douglas, Alsweiler, Caroline, Devlin, Gerard Patrick, Low, Liz, Fisher, Raewyn, Scales, Jayne, Abercrombie, Kirsty, Stewart, Ralph Alan Huston, Howell, Leah, White, Harvey Douglas, Patten, Cathrine, Benatar, Jocelyne, Kedev, Sasko, Mitevska, Irena Peovska, Kostovska, Elizabeta Srbinovska, Pejkov, Hristo, Held, Claes, Held, Claes, Eggers, Kai, Frostfelt, Gunnar, Björklund, Christina, Johnston, Nina, Andreasson, Maria, Olsowka, Maciej, Essermark, Marie, Åkerblom, Axel, Soveri, Inga, Aspberg, Johannes, Persson, Liselotte, Beyar, Rafael, Sharir, Tali, Nikolsky, Eugenia, Sharir, Tali, Harel, Or, Elian, Dan, Kerner, Arthur, Bentzvi, Margalit, Massalha, Samia, Helmer, Ludmila, Kohsaka, Shun, Fukuda, Keiichi, Ueda, Ikuko, Kohsaka, Shun, Fujita, Jun, Yasuda, Satoshi, Furukawa, Akemi, Hirase, Kanae, Nagai, Toshiyuki, Otsuka, Fumiyuki, Nishimura, Shigeyuki, Nakano, Shintaro, de Werf, Frans Van, Goetschalckx, Kaatje, Goetschalckx, Kaatje, Robesyn, Valerie, de Werf, Frans Van, Claes, Kathleen, White, Harvey Douglas, Alsweiler, Caroline, Hung, Chung-Lieh, Yang, Yi-Hsuan, Yun, Chun-Ho, Hou, Charles Jia-Yin, Kuo, Jen-Yuan, Yeh, Hung-I, Hung, Ta-Chuan, Li, Jiun-Yi, Chien, Chen-Yen, Tsai, Cheng-Ting, Liu, Chun-Chieh, Yu, Fa-Chang, Lin, Yueh-Hung, Lan, Wei-Ren, Yen, Chih-Hsuan, Tsai, Jui-Peng, Sung, Kuo-Tzu, Ntsekhe, Mpiko, Pandie, Shaheen, Philander (Nee Talliard), Constance, Viljoen, Charle A, Mtana, Noloyiso, De Andrade, Marianne, Maggioni, Aldo P., Moccetti, Tiziano, Anesini, Adriana, Rossi, M.Grazia, Maspoli, Simona, Mombelli, Manuela, Abdelhamid, Magdy, Talaat, Ahmed, Adel, Ahmed, Kamal, Ahmed, Mahrous, Hossam, Kaffas, Sameh El, Fishawy, Hussien El, Pop, Calin, Claudia, Matei, Popescu, Bogdan A., Ginghina, Carmen, Rosca, Monica, Deleanu, Dan, Beladan, Carmen C., Iliescu, Vlad A., Al-Mallah, Mouaz H., Zahrani, Sarah, Aljzeeri, Ahmed, Najm, Hani, Alghamdi, Ali, Mogrovejo Ramos, Walter Enrique, Monsalve Davila, Marco Antonio, White, Harvey Douglas, Alsweiler, Caroline, Kuanprasert, Srun, Mai, Chiang, Prommintikul, Arintaya, Nawarawong, Weerachai, Khwakhong, Supatchara, Woragidpoonpol, Surin, Chaiyasri, Anong, Tepsuwan, Thitipong, Mekara, Warangkana, Taksaudom, Noppon, Kulthawong, Supap, Rimsukcharoenchai, Chataroon, Amaritakomol, Anong, Euathrongchit, Juntima, Wannasopha, Yutthaphan, Yamwong, Sukit, Panpunuan, Pachara, Sritara, Piyamitr, Aramcharoen, Suthara, Meemuk, Krissada, White, Harvey Douglas, Alsweiler, Caroline, Khairuddin, Ahmad, Mokhtar, Noor Syamira, Hadi, Hafidz Abd, Basri, Nor Asiah, Yahaya, Shaiful Azmi, Yusnida, Irni, Hashim, Humayrah, Harrington, Robert, Williams, David, Alexander, Karen P., Berger, Jeffrey, Harrington, Robert, Mark, Daniel, O’Brien, Sean M., Rosenberg, Yves, Shaw, Leslee J., Ballantyne, Christie, Berman, Daniel, Beyar, Rafael, Bhargava, Balram, Buller, Chris, (Tony) Carvalho*, Antonio, Chaitman, Bernard R., Diaz, Rafael, Doerr, Rolf, Dzavik, Vladimir, Goodman, Shaun, Gosselin, Gilbert, Hachamovitch, Rory, Hamm, Christian, Held, Claes, Helm, Malte, Huber, Kurt, Jiang, Lixin, Keltai, Matyas, Kohsaka, Shun, Lang, Irene, Lopes, Renato, Lopez-Sendon, Jose, Maggioni, Aldo, Bairey Merz, C. Noel, Min, James, Peterson, Eric, Picard, Michael H., Selvanayagam, Joseph, Senior, Roxy, Sharir, Tali, Steg, Gabriel, Szwed, Hanna, de Werf, Frans Van, Weintraub, William, White, Harvey, Williams, David, Ballantyne, Christie, Calfas*, Karen, Chaitman, Bernard R., Champagne, Mary Ann, Davidson, Michael, Fleg, Jerome, McCullough, Peter A., Stone, Peter, Menasche, Philippe, Davidson*, Michael, Fremes, Stephen, Guyton, Robert, Mack, Michael, Mohr, Fred, Rao, Anupama, Sabik, Joe, Shapira, Oz, Taggart, David, Tatoulis, James, Williams, David, Blankenship, Jim, Brener, Sorin, Buller, Chris, Colombo, Antonio, Bruyne, Bernard de, Généreux, Philippe, Harrington, Robert, Kereiakes, Dean, Lefevre, Thierry, Moses, Jeffrey, Chaitman, Bernard R., Alexander, Karen P., Mahaffey, Ken, White, Harvey, Chaitman, Bernard R., Cruz-Flores, Salvador, Danchin, Nicholas, Feen, Eli, Garcia, Mario J., Hauptman, Paul, Laddu, Abhay A., Passamani, Eugene, Pina, Ileana L., Simoons, Maarten, Skali, Hicham, Thygesen, Kristian, Waters, David, Alexander, Karen P., Endsley, Patricia, Esposito, Gerard, Kanters, Jeffrey, Pownall, John, Stournaras, Dimitrios, Shaw, Leslee J., Berman, Daniel, Friedrich, Matthias, Hachamovitch, Rory, Kwong, Raymond, Min, James, Oliver, Dana, Picard, Michael H., Harrell, Frank, Blume, Jeffrey, Lee, Kerry, O’Brien, Sean M., Berger, Jeffrey, Held, Claes, Kullo, Iftikhar, McManus, Bruce, Newby, Kristin, Mark, Daniel, Cohen, David, Weintraub, William, Merz, C. Noel Bairey, Bugiardini, Raffaele, Celutkiene, Jelena, Escobedo, Jorge, Hoye, Angela, Lyubarova, Radmila, Mattina, Deirdre, Peteiro, Jesus, Alexander, Karen P., Berger, Jeffrey, Harrington, Robert, O’Brien, Sean M., Rosenberg, Yves, Mark, Daniel, Mark, Daniel, Shaw, Leslee J., Berman, Dan, Chaitman, Bernard R., Fleg, Jerome, Kwong, Raymond, Picard, Michael H., Senior, Roxy, Min, James, Leipsic, Jonathan, Ali, Ziad, Williams, David, Fleg, Jerome, Berger, Jeffrey, Chaitman, Bernard R., Alexander, Karen P., Alexander, Karen P., Fleg, Jerome, Mathew, Roy, O’Brien, Sean M., Sidhu, Mandeep, Friedman, Lawrence, Anderson, Jeffrey, Berg, Jessica, DeMets, David, Gibson, C. 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James, Hyun, Mark, Miranda-Peats, Romalisa, Slomka, Piotr, Thomson, Louise, Kwong, Raymond Y., Friedrich, Matthias, Mongeon, Francois Pierre, Michael, Steven, Picard, Michael H., Hung, Judy, Scherrer-Crosbie, Marielle, Zeng, Xin, Chaitman, Bernard R., Eckstein, Jane, Guruge, Bandula, Streif, Mary, Ali, Ziad, Genereux, Philippe, Alfonso, Maria A., Corral, Maria P., Garcia, Javier J., Horst, Jennifer, Jankovic, Ivana, Konigstein, Maayan, Lustre, Mitchel B., Peralta, Yolayfi, Sanchez, Raquel, Min, James, Arsanjani, Reza, Budoff, Matthew, Elmore, Kimberly, Gomez, Millie, Hague, Cameron, Hindoyan, Niree, Leipsic, Jonathan, Nakanishi, Rine, Srichai-Parsia, M. Barbara, Yeoh, Eunice, Youn, Tricia, Maggioni, Aldo P., Bianchini, Francesca, Ceseri, Martina, Lorimer, Andrea, Magnoni, Marco, Orso, Francesco, Sarti, Laura, Tricoli, Martinia, Carvalho, Antonio, Lopes, Renato, Barbosa, Lilian Mazza, Duarte, Tauane Bello, Soares, Tamara Colaiácovo, Aveiro Morata, Julia de, Carvalho, Pedro, Carvalho Maffei, Natalia de, Egydio, Flávia, Kawakami, Anelise, Oliveira, Janaina, Piloto, Elissa Restelli, Pozzibon, Jaqueline, Goodman, Shaun, Camara, Diane, Mowafy, Neamat, Spindler, Caroline, Jiang, Lixin, Dai, Hao, Feng, Fang, Li, Jia, Li, Li, Liu, Jiamin, Xie, Qiulan, Zhang, Haibo, Zhang, Jianxin, Zhang, Lihua, Zhang, Liping, Zhang, Ning, Zhong, Hui, Diaz, Rafael, Escobar, Claudia, Martin, Maria Eugenia, Pascual, Andrea, Lopez-Sendon, José, Moraga, Paloma, Hernandez, Victoria, Castro, Almudena, Posada, Maria, Fernandez, Sara, Villanueva, José Luis Narro, Selgas, Rafael, Steg, Gabriel, Abergel, Helene, Juliard, Jean Michel, White, Harvey, Alsweiler, Caroline, de Werf, Frans Van, Claes, Kathleen, Goetschalckx, Kaatje, Luyten, Ann, Robesyn, Valerie, Selvanayagam, Joseph B., Murphy, Deirdre, Ahmed, Asker, Bhatt, Richa, Chadha, Nitika, Kumar, Vijay, Lubna, Sadath, Naik, Pushpa, Pandey, Shruti, Ramasamy, Karthik, Saleem, Mohammed, Sharma, Pratiksha, and Siddaram, Hemalata
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- 2024
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3. Differences in quantitative myocardial perfusion mapping by CMR at 1.5 T and 3 T
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Abraham, George R., Berry, Colin, Fu, Qing, Hoole, Stephen P., and Weir-McCall, Jonathan R.
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- 2024
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4. Percutaneous Left Ventricular Unloading During High-Risk Coronary Intervention: Rationale and Design of the CHIP-BCIS3 Randomized Controlled Trial
- Author
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Ryan, Matthew, Ezad, Saad M., Webb, Ian, O’Kane, Peter D., Dodd, Matthew, Evans, Richard, Laidlaw, Lynn, Khan, Sohail Q., Weerackody, Roshan, Bagnall, Alan, Panoulas, Vasileios F., Rahman, Haseeb, Strange, Julian W., Fath-Ordoubadi, Farzin, Hoole, Stephen P., Stables, Rod H., Curzen, Nick, Clayton, Tim, and Perera, Divaka
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- 2024
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5. Correcting common OCT artifacts enhances plaque classification and identification of higher-risk plaque features
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Jessney, Benn, Chen, Xu, Gu, Sophie, Brown, Adam, Obaid, Daniel, Costopoulos, Charis, Goddard, Martin, Shah, Nikunj, Garcia-Garcia, Hector, Onuma, Yoshinobu, Serruys, Patrick, Hoole, Stephen P., Mahmoudi, Michael, Roberts, Michael, and Bennett, Martin
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- 2024
- Full Text
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6. Current strategies for managing chronic thromboembolic pulmonary hypertension: results of the worldwide prospective CTEPH Registry
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Guth, Stefan, D'Armini, Andrea M, Delcroix, Marion, Nakayama, Kazuhiko, Fadel, Elie, Hoole, Stephen P, Jenkins, David P, Kiely, David G, Kim, Nick H, Lang, Irene M, Madani, Michael M, Matsubara, Hiromi, Ogawa, Aiko, Ota-Arakaki, Jaquelina S, Quarck, Rozenn, Sadushi-Kolici, Roela, Simonneau, Gérald, Wiedenroth, Christoph B, Yildizeli, Bedrettin, Mayer, Eckhard, and Pepke-Zaba, Joanna
- Subjects
Rare Diseases ,Lung ,Cardiovascular - Abstract
Pulmonary endarterectomy (PEA), pulmonary arterial hypertension (PAH) therapy and balloon pulmonary angioplasty (BPA) are currently accepted therapies for chronic thromboembolic pulmonary hypertension (CTEPH). This international CTEPH Registry identifies clinical characteristics of patients, diagnostic algorithms and treatment decisions in a global context. 1010 newly diagnosed consecutive patients were included in the registry between February 2015 and September 2016. Diagnosis was confirmed by right heart catheterisation, ventilation-perfusion lung scan, computerised pulmonary angiography and/or invasive pulmonary angiography after at least 3 months on anticoagulation. Overall, 649 patients (64.3%) were considered for PEA, 193 (19.1%) for BPA, 20 (2.0%) for both PEA and BPA, and 148 (14.7%) for PAH therapy only. Reasons for PEA inoperability were technical inaccessibility (n=235), comorbidities (n=63) and patient refusal (n=44). In Europe and America and other countries (AAO), 72% of patients were deemed suitable for PEA, whereas in Japan, 70% of patients were offered BPA as first choice. Sex was evenly balanced, except in Japan where 75% of patients were female. A history of acute pulmonary embolism was reported for 65.6% of patients. At least one PAH therapy was initiated in 35.8% of patients (26.2% of PEA candidates, 54.5% of BPA candidates and 54.1% of those not eligible for either PEA or BPA). At the time of analysis, 39 patients (3.9%) had died of pulmonary hypertension-related causes (3.5% after PEA and 1.8% after BPA). The registry revealed noticeable differences in patient characteristics (rates of pulmonary embolism and sex) and therapeutic approaches in Japan compared with Europe and AAO.
- Published
- 2021
7. The Index of Microcirculatory Resistance After Primary PCI: A Pooled Analysis of Individual Patient Data
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El Farissi, Mohamed, Zimmermann, Frederik M., De Maria, Giovanni Luigi, van Royen, Niels, van Leeuwen, Maarten A.H., Carrick, David, Carberry, Jaclyn, Wijnbergen, Inge F., Konijnenberg, Lara S.F., Hoole, Stephen P., Marin, Federico, Fineschi, Massimo, Pijls, Nico H.J., Oldroyd, Keith G., Banning, Adrian P., Berry, Collin, and Fearon, William F.
- Published
- 2023
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8. Prognostic Value of Microvascular Resistance Reserve After Percutaneous Coronary Intervention in Patients With Myocardial Infarction
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Eerdekens, Rob, primary, El Farissi, Mohamed, additional, De Maria, Giovanni Luigi, additional, van Royen, Niels, additional, van ‘t Veer, Marcel, additional, van Leeuwen, Maarten A.H., additional, Hoole, Stephen P., additional, Marin, Federico, additional, Carrick, David, additional, Tonino, Pim A.L., additional, Pijls, Nico H.J., additional, Fineschi, Massimo, additional, Oldroyd, Keith G., additional, Berry, Colin, additional, Banning, Adrian P., additional, Fearon, William F., additional, and Zimmermann, Frederik M., additional
- Published
- 2024
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9. Computed tomography pericoronary adipose tissue density predicts coronary allograft vasculopathy and adverse clinical outcomes after cardiac transplantation
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Wall, Christopher, primary, Weir-McCall, Jonathan, additional, Tweed, Katharine, additional, Hoole, Stephen P, additional, Gopalan, Deepa, additional, Huang, Yuan, additional, Corovic, Andrej, additional, Peverelli, Marta, additional, Dey, Damini, additional, Bennett, Martin R, additional, Rudd, James H F, additional, Kydd, Anna, additional, Bhagra, Sai, additional, and Tarkin, Jason M, additional
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- 2024
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10. Sex Differences in Revascularization, Treatment Goals, and Outcomes of Patients With Chronic Coronary Disease: Insights From the ISCHEMIA Trial
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Reynolds, Harmony R., primary, Cyr, Derek D., additional, Merz, C. Noel Bairey, additional, Shaw, Leslee J., additional, Chaitman, Bernard R., additional, Boden, William E., additional, Alexander, Karen P., additional, Rosenberg, Yves D., additional, Bangalore, Sripal, additional, Stone, Gregg W., additional, Held, Claes, additional, Spertus, John, additional, Goetschalckx, Kaatje, additional, Bockeria, Olga, additional, Newman, Jonathan D., additional, Berger, Jeffrey S., additional, Elghamaz, Ahmed, additional, Lopes, Renato D., additional, Min, James K., additional, Berman, Daniel S., additional, Picard, Michael H., additional, Kwong, Raymond Y., additional, Harrington, Robert A., additional, Thomas, Boban, additional, O'Brien, Sean M., additional, Maron, David J., additional, Hochman, Judith S., additional, Mavromatis, Kreton, additional, Linefsky, Jason, additional, Miller, Todd, additional, Banerjee, Subhash, additional, Reynolds, Harmony R., additional, Donnino, Robert M., additional, Phillips, Lawrence M., additional, Saric, Muhamed, additional, Abdul‐Nour, Khaled, additional, Stone, Peter H., additional, Jang, James J., additional, Yee, Gennie, additional, Weitz, Steven, additional, Arnold, Suzanne, additional, O’Keefe, James Henry, additional, Shapiro, Michael D., additional, El‐Hajjar, Mohammad, additional, Sidhu, Mandeep S., additional, Fein, Steven A., additional, Torosoff, Mikhail T., additional, Lyubarova, Radmila, additional, Mookherjee, Sulagna, additional, Drzymalski, Krzysztof, additional, McFalls, Edward O., additional, Garcia, Santiago A., additional, Bertog, Stefan C., additional, Siddiqui, Rizwan A., additional, Ishani, Areef, additional, Hansen, Ronnell A., additional, Khouri, Michel Georges, additional, Goldberg, Jonathan L., additional, Goldweit, Richard, additional, Cohen, Ronny A., additional, Mirrer, Brooks, additional, Navarro, Victor, additional, Winchester, David E., additional, Kronenberg, Marvin, additional, Rogal, Philip, additional, McFarren, Christopher, additional, Heitner, John F., additional, Dauber, Ira M., additional, Cannan, Charles, additional, Sudarshan, Sriram, additional, Mehta, Puja K., additional, McDaniel, Michael, additional, Lerakis, Stamatios, additional, Quyyumi, Arshed, additional, Wenger, Nanette K., additional, Hedgepeth, Chester M., additional, Hurlburt, Heather, additional, Rosen, Alan, additional, Sahul, Zakir, additional, Booth, David, additional, Leung, Steve, additional, Abdel‐Latif, Ahmed, additional, Reda, Hassan, additional, Ziada, Khaled, additional, Setty, Sampoornima, additional, Barua, Rajat S., additional, Hage, Fadi, additional, Caldeira, Christiano, additional, Davies, James E., additional, Leesar, Massoud, additional, Heo, Jaekyeong, additional, Iskandrian, Amy, additional, Al Solaiman, Firas, additional, Singh, Satinder, additional, Dajani, Khaled, additional, Der Mesropian, Paul, additional, Sacco, Joseph, additional, McCandless, Brian, additional, Orgera, Marisa, additional, Arif, Imran, additional, Kerr, Hanan, additional, Trejo (Gutierrez), Jorge F., additional, Fletcher, Gerald, additional, Lane, Gary E., additional, Neeson, Lynn M., additional, Parikh, Pragnesh P., additional, Pollak, Peter M., additional, Shapiro, Brian P., additional, Landolfo, Kevin, additional, Gemignani, Anthony, additional, O’Rourke, Daniel, additional, Meadows, Judith L., additional, Call, Jason T., additional, Hannan, Joseph, additional, Bojar, Robert, additional, Kumar, Deepti, additional, Mukai, John, additional, Martin, Edward T., additional, Vorobiof, Gabriel, additional, Moorman, Alec, additional, Kinlay, Scott, additional, Hamburger, Robert J., additional, Rocco, Thomas P., additional, Bhatt, Deepak L., additional, Croce, Kevin, additional, Quin, Jacquelyn A., additional, Anumpa, Jati, additional, Zenati, Marco, additional, Faxon, David P., additional, Rayos, Glenn, additional, Seedhom, Ashraf, additional, Sullenberger, Lance, additional, Kumkumian, Gregory, additional, Sedlis, Steven P., additional, Donnino, Robert M., additional, Lorin, Jeffrey, additional, Tamis‐Holland, Jacqueline E., additional, Kornberg, Robert, additional, Leber, Robert, additional, Saba, Souheil, additional, Lee, Michael W., additional, Small, Delano R., additional, Nona, Wassim, additional, Alexander, Patrick B., additional, Rehman, Iram, additional, Badami, Umesh, additional, Marzo, Kevin, additional, Robbins, Inga H., additional, Levite, Howard A., additional, Shetty, Sanjay, additional, Patel, Mayuri, additional, Hamroff, Glenn S., additional, Little, Raymond W., additional, Zimbelman, Brandi D., additional, Lui, Charles Y., additional, Smith, Brigham R., additional, Vezina, Daniel P., additional, Khor, Lillian L., additional, Abraham, Josephine D., additional, Bull, David A., additional, McKellar, Stephen H., additional, Kotter, John, additional, Hu, Bob, additional, Labovitz, Arthur J., additional, Berlowitz, Michael, additional, Matar, Fadi, additional, Rodriguez, Fatima, additional, Schnittger, Ingela, additional, Fearon, William F., additional, Deedwania, Prakash, additional, Reddy, Kiran, additional, Sweeny, Joseph, additional, Spizzieri, Christopher, additional, Hochberg, Claudia P., additional, Salerno, William D., additional, Wyman, Ray, additional, Zarka, Amer, additional, Shah, Anil V., additional, Haldis, Thomas, additional, Kohn, Jeffrey A., additional, Girotra, Saket, additional, Almousalli, Omar, additional, Krishnam, Mayil S., additional, Milliken, Jeffrey C., additional, Patel, Pranav M., additional, Seto, Arnold H., additional, Harley, Kevin T., additional, Gibson, Michael A., additional, Allen, Byron J., additional, Coram, Rita, additional, Thomas, Sabu, additional, Schwartz, Ronald G., additional, Chen, Wei, additional, El Shahawy, Mahfouz, additional, Stafford, James, additional, Abernethy, William B., additional, Zurick, Andrew, additional, Meyer, Thomas M., additional, Morford, Ronald G., additional, Rutkin, Bruce, additional, Bokhari, Sabahat, additional, Sokol, Seth I., additional, Meisner, Jay, additional, Hamzeh, Ihab, additional, Misra, Arunima, additional, Wall, Matthew, additional, De Rosen, Veronica Lenges, additional, Alam, Mahboob, additional, Turner, Michael C., additional, Mulhearn, Thomas J., additional, Good, Arnold P., additional, Shammas, Nicolas W., additional, Chilton, Robert, additional, Nguyen, Patricia K., additional, Jezior, Matthew, additional, Gordon, Paul C., additional, Crain, Thomas, additional, Stenberg, Robert, additional, Pedalino, Ronald P., additional, Wiesel, Joseph, additional, Juang, George J., additional, Al‐Amoodi, Mohammed, additional, Wohns, David, additional, Lader, Ellis W., additional, Mumma, Michael, additional, Dharmarajan, Lekshmi, additional, McGarvey, Joseph F. X., additional, Downes, Thomas R., additional, Luckasen, Gary J., additional, Cheong, Benjamin, additional, Potluri, Srinivasa, additional, Mastouri, Ronald A., additional, Breall, Jeffery A., additional, Revtyak, George E., additional, Bazeley, Jonathan W., additional, Li, Dayuan, additional, Giedd, Kenneth, additional, Old, Wayne, additional, Burt, Francis, additional, Sokhon, Kozhaya, additional, Gopal, Deepika, additional, Valeti, Uma S., additional, Kobashigawa, Jon, additional, Govindan, Sajeev Chakanalil, additional, Nair, Rajesh Gopalan, additional, Manjunath, Cholenahally Nanjappa, additional, Moorthy, Nagaraja, additional, Manjunath, Satvic Cholenahally, additional, Narayanappa, Suryaprakash, additional, Pandit, Neeraj, additional, Nath, Ranjit Kumar, additional, Dwivedi, S. K., additional, Narain, V. S., additional, Chandra, Sharad, additional, Wander, Gurpreet S., additional, Tandon, Rohit, additional, Ralhan, Sarju, additional, Aslam, Naved, additional, Goyal, Abhishek, additional, Bhargava, Balram, additional, Karthikeyan, G., additional, Ramakrishnan, S., additional, Seth, Sandeep, additional, Yadav, Rakesh, additional, Singh, Sandeep, additional, Roy, Ambuj, additional, Parakh, Neeraj, additional, Verma, Sunil Kumar, additional, Narang, Rajiv, additional, Mishra, Sundeep, additional, Naik, Nitish, additional, Sharma, Gautam, additional, Choudhary, Shiv Kumar, additional, Patel, Chetan, additional, Gulati, Gurpreet, additional, Sharma, Sanjeev, additional, Bahl, V. K., additional, Mathew, Anoop, additional, Punnoose, Eapen, additional, Gadkari, Milind Avdhoot, additional, Gadage, Siddharth, additional, Pillay, Tapan Umesh, additional, Satheesh, Santhosh, additional, Mathur, Atul, additional, Kaul, Upendra, additional, Christopher, Johann, additional, Menon, Rajeev, additional, Kumar, Nirmal, additional, Oomman, Abraham, additional, Mao, Robert, additional, Solomon, Hilda, additional, Naik, Sudhir, additional, Khan, Sajeeda Parveen, additional, Grant, Purvez, additional, Kachru, Ranjan, additional, Ajit Kumar, V. K., additional, Ganapathi, Sanjay, additional, Jayakumar, K., additional, Sivadasanpillai, Harikrishnan, additional, Sasidharan, Bijulal, additional, Kapilamoorthy, T. R., additional, Polamuri, Praneeth, additional, Senior, Roxy, additional, Gurunathan, Sothinathan, additional, Karogiannis, Nikolaos, additional, Shah, Benoy N., additional, Trimlett, Richard HJ, additional, Rubens, Michael B., additional, Nicol, Edward D., additional, Mittal, Tarun K., additional, Hampson, Reinette, additional, Gamma, Reto Andreas, additional, de Belder, Mark A., additional, Thambyrajah, Jeet, additional, Nageh, Thuraia, additional, Davies, John R., additional, Lindsay, Steven J., additional, Kurian, John, additional, Jamil, Haqeel, additional, Raheem, Osama, additional, Hoye, Angela, additional, Donnelly, Patrick, additional, Valecka, Bernardas, additional, Chauhan, Anoop, additional, Barr, Craig, additional, Alfakih, Khaled, additional, Byrne, Jonathan, additional, Webb, Ian, additional, Henriksen, Peter, additional, OKane, Peter, additional, de Silva, Ramesh, additional, Conway, Dwayne S. G., additional, Sirker, Alexander A, additional, Hoole, Stephen P., additional, Witherow, Fraser N., additional, Johnston, Nicola, additional, Harbinson, Mark, additional, Walsh, Simon, additional, Douglas, Hanna, additional, Luckie, Matthew, additional, Sobolewska, Jolanta, additional, Jeetley, Paramjit, additional, Patel, Niket, additional, Kotecha, Tushar, additional, Travill, Christopher, additional, Karimullah, Iqbal, additional, Al‐Bustami, Mahmud, additional, Braganza, Denise, additional, Henderson, Robert, additional, Pointon, Kate, additional, Naik, Surendra, additional, Mathew, Thomas, additional, Berry, Colin, additional, Collison, Damien, additional, Roditi, Giles, additional, Moriarty, Andrew J., additional, Glover, Jason D., additional, Pradhan, Jiwan, additional, Mikhail, Ghada, additional, Francis, Darrel P., additional, Gosselin, Gilbert, additional, Diaz, Ariel, additional, Rheault, Philippe, additional, Barrero, Miguel, additional, Gagné, Carl‐Éric, additional, Pépin‐Dubois, Yanek, additional, Costa, Ricardo, additional, Sia, Ying Tung, additional, Lemay, Catherine, additional, Gisbert, Alejandro, additional, Gervais, Pierre, additional, Rheault, Alain, additional, Phaneuf, Denis Carl, additional, Garg, Pallav, additional, Chow, Benjamin J. W., additional, Hessian, Renee C., additional, Beanlands, Rob S., additional, Davies, Richard F., additional, Bainey, Kevin R., additional, Cheema, Asim N., additional, Bagai, Akshay, additional, Wald, Ron, additional, Goodman, Shaun, additional, Graham, John Joseph, additional, Peterson, Mark, additional, Chow, Chi‐Ming, additional, Abramson, Beth, additional, Cheema, Asim Nazir, additional, Vakani, Mohammad Tariq, additional, Cha, James, additional, Howarth, Andrew G, additional, Wong, Graham, additional, Uxa, Amar, additional, Galiwango, Paul, additional, Kassam, Saleem, additional, Mukherjee, Ashok, additional, Ricci, A. Joseph, additional, Lam, Andy, additional, Mehta, Shamir, additional, Udell, Jacob, additional, Généreux, Philippe, additional, Hameed, Adnan, additional, Daba, Ledjalem, additional, Hueb, Whady, additional, Rezende, Paulo Cury, additional, Silva, Expedito Eustáquio Ribeiro, additional, Hueb, Alexandre Ciappina, additional, Smanio, Paola Emanuela Poggio, additional, de Quadros, Alexandre Schaan, additional, Kalil, Renato Abdala Karam, additional, da Costa Vieira, José Luiz, additional, Grossmann, Gabriel, additional, de Oliveira, Pedro Píccaro, additional, Bridi, Leonardo, additional, Savaris, Simone, additional, Vitola, João V., additional, Cerci, Rodrigo J., additional, Farias, Fabio R., additional, Fernandes, Miguel M., additional, Marin‐Neto, José Antonio, additional, Schmidt, André, additional, de Oliveira Lima Filho, Moysés, additional, Oliveira, Ricardo Mendes, additional, Chierice, João Reynaldo Abbud, additional, Polanczyk, Carísi A., additional, Furtado, Mariana V., additional, Smidt, Luis F., additional, Carvalho, Antonio Carlos, additional, Pucci, Gustavo, additional, Lyra, Flavio, additional, Junior, Alvaro Rabelo Alves, additional, Dracoulakis, Marianna D. A., additional, Lima, Rodolfo G. S. D, additional, Figueiredo, Estevao, additional, Caramori, Paulo Ricardo, additional, Tumelero, Rogerio, additional, Dall’Orto, Frederico, additional, Mesquita, Claudio T., additional, Colafranseschi, Alexandre S., additional, Oliveira, Amarino C., additional, Carvalho, Luiz A., additional, Palazzo, Isabella C., additional, Sousa, Andre S., additional, da Silva, Expedito Eustáquio Ribeiro, additional, de Barros, Pedro Gabriel Melo, additional, de Pádua Silva Baptista, Luciana, additional, Rodrigues, Marcelo Jamus, additional, de Resende, Marcos Valério Coimbra, additional, Saraiva, Jose Francisco, additional, Costantini, Costantino, additional, Demkow, Marcin, additional, Pracon, Radoslaw, additional, Kepka, Cezary, additional, Teresinska, Anna, additional, Kryczka, Karolina, additional, Henzel, Jan, additional, Solecki, Mateusz, additional, Kaczmarska, Edyta, additional, Mazurek, Tomasz, additional, Drozdz, Jaroslaw, additional, Czarniak, Bartosz, additional, Frach, Malgorzata, additional, Szymczyk, Konrad, additional, Niedzwiecka, Iwona, additional, Sobczak, Sebastian, additional, Ciurus, Tomasz, additional, Jakubowski, Piotr, additional, Misztal‐Teodorczyk, Magdalena, additional, Teodorczyk, Dawid, additional, Fratczak, Aleksandra, additional, Szkopiak, Marcin, additional, Lebioda, Patrycja, additional, Wlodarczyk, Michal, additional, Plachcinska, Anna, additional, Kusmierek, Jacek, additional, Miller, Magdalena, additional, Marciniak, Halina, additional, Wojtczak‐Soska, Karolina, additional, Luczak, Katarzyna, additional, Tarchalski, Tomasz, additional, Cichocka‐Radwan, Anna, additional, Szwed, Hanna, additional, Szulczyk, Grazyna Anna, additional, Witkowski, Adam, additional, Kukula, Krzysztof, additional, Celinska‐Spodar, Malgorzta, additional, Zalewska, Joanna, additional, Gajos, Grzegorz, additional, Bury, Krzysztof, additional, Pruszczyk, Piotr, additional, Roik, Marek, additional, Loboz‐Grudzien, Krystyna, additional, Sokalski, Leszek, additional, Brzezinska, Barbara, additional, Lesiak, Maciej, additional, Lanocha, Magdalena, additional, Reczuch, Krzysztof W., additional, Kalarus, Zbigniew, additional, Swiatkowski, Andrzej, additional, Szulik, Mariola, additional, Musial, Wlodzimierz J., additional, Bockeria, Leo, additional, Petrosyan, Karen, additional, Trifonova, Tatiana, additional, Chernyavskiy, Alexander M., additional, Kretov, Evgeniy I., additional, Grazhdankin, Igor O., additional, Bershtein, Leonid L., additional, Sayganov, Sergey A., additional, Kuzmina‐Krutetskaya, Anastasia M., additional, Zbyshevskaya, Elizaveta V., additional, Katamadze, Nana O., additional, Demchenko, Elena A., additional, Kozlov, Pavel S., additional, Kozulin, Vikentiy Y., additional, Lubinskaya, Ekaterina I., additional, Lopez‐Sendon, Jose, additional, Castro, Almudena, additional, Salicio, Elena Refoyo, additional, Guzman, Gabriela, additional, Galeote, Gabriel, additional, Valbuena, Silvia, additional, Peteiro, Jesús, additional, Martínez‐Ruíz, María Dolores, additional, Pérez‐Fernández, Ruth, additional, Cuenca‐Castillo, José J., additional, Flores‐Ríos, Xacobe, additional, Prada‐Delgado, Óscar, additional, Barge‐Caballero, Gonzalo, additional, Juanatey, Jose Ramon Gonzalez, additional, Bayarri, Miguel Souto, additional, Nuñez, Virginia Pubull, additional, Sanchez, Raymundo Ocaranza, additional, Alvarez, Belen Cid, additional, Gil, Carlos Peña, additional, Monzonis, Amparo Martinez, additional, Sionis, Alessandro, additional, Perales, Montserrat Vila, additional, Padró, Josep Maria, additional, Peñaranda, Antonio Serra, additional, Picart, Joan García, additional, Iglesias, Antonino Ginel, additional, Marimon, Xavier Garcia‐Moll, additional, Lladó, Guillem Pons, additional, Costa, Francesc Carreras, additional, Miro, Vicente, additional, Diez, Jose L., additional, Calvillo, Pilar, additional, Ortuño, F. Marin, additional, Chávarri, M. Valdés, additional, Montolliu, A. Tello, additional, Bermudez, E. Pinar, additional, De La Morena, G., additional, Blancas, Montserrat Gracida, additional, Luena, Jose Enrique Castillo, additional, Fernandez‐Aviles, Francisco, additional, Chen, Jiyan, additional, Wu, Yongjian, additional, Ma, Yitong, additional, Yang, Yining, additional, Ji, Zheng, additional, Yang, Xinchun, additional, Lin, Wenhua, additional, Zeng, Hesong, additional, Fu, Xin, additional, Yang, Bin, additional, Wang, Songtao, additional, Cheng, Gong, additional, Zhao, Yulan, additional, Fang, Xuehua, additional, Zeng, Qiutang, additional, Su, Xi, additional, Li, Qingxian, additional, Nie, Shao‐ping, additional, Yu, Qin, additional, Wang, Jian’an, additional, Zhang, Shuyang, additional, Liu, Zhenyu, additional, Perna, Gian Piero, additional, Marini, Marco, additional, Gabrielli, Gabriele, additional, Provasoli, Stefano, additional, Verna, Edoardo, additional, Monti, Lorenzo, additional, Nardi, Barbara, additional, Di Chiara, Antonio, additional, Mortara, Andrea, additional, Galvani, Marcello, additional, Ottani, Filippo, additional, Sicuro, Marco, additional, Calabro, Paolo, additional, Formisano, Tiziana, additional, Tarantini, Giuseppe, additional, Cucchini, Umberto, additional, Andres, Anto Luigi, additional, Racca, Emanuela, additional, Briguori, Carlo, additional, Amati, Roberto, additional, Vergoni, William, additional, Russo, Aldo, additional, Fanelli, Raffaele, additional, Poh, Kian‐Keong, additional, Chai, Ping, additional, Lau, Titus, additional, Loh, Joshua P., additional, Tay, Edgar L., additional, Teoh, Kristine, additional, Teo, Lynette L., additional, Ong, Ching‐Ching, additional, Wong, Raymond C., additional, Loh, Poay‐Huan, additional, Kofidis, Theodoros, additional, Chan, Wan Xian, additional, Chan, Koo Hui, additional, Foo, David, additional, Kong, Jason Loh Kwok, additional, Er, Ching Min, additional, Jafary, Fahim Haider, additional, Chua, Terrance, additional, Doerr, Rolf, additional, Stumpf, Juergen, additional, Matschke, Klaus, additional, Simonis, Gregor, additional, Kadalie, Clemens T., additional, Sechtem, Udo, additional, Ong, Peter, additional, Schulze, P. Christian, additional, Goebel, Bjoern, additional, Lenk, Karsten, additional, Nickenig, Georg, additional, Schuchlenz, Herwig, additional, Weikl, Stefan, additional, Lang, Irene Marthe, additional, Huber, Kurt, additional, Jakl‐Kotauschek, Gabriele, additional, Vertes, Andras, additional, Varga, Albert, additional, Fontos, Geza, additional, Merkely, Bela, additional, Kerecsen, Gabor, additional, Hinic, Sasa, additional, Zdravkovic, Marija, additional, Mudrenovic, Vladan, additional, Crnokrak, Bogdan, additional, Beleslin, Branko D., additional, Boskovic, Nikola N., additional, Petrovic, Marija T., additional, Dobric, Milan R., additional, Markovic, Zeljko Z., additional, Mladenovic, Ana S., additional, Cemerlic‐Adjic, Nada, additional, Davidovic, Goran, additional, Vucic, Rada, additional, Dekleva, Milica Nikola, additional, Stankovic, Goran, additional, Apostolovic, Svetlana, additional, Escobedo, Jorge, additional, Baleón‐Espinosa, Rubén, additional, Campos‐Santaolalla, Arturo S., additional, Durán‐Cortés, Elihú, additional, Flores‐Palacios, José M., additional, García‐Rincón, Andrés, additional, Jiménez‐Santos, Moisés, additional, Peñafiel, Joaquín V., additional, Ortega‐Ramírez, José A., additional, Valdespino‐Estrada, Aquiles, additional, Rosas, Erick Alexánderson, additional, Selvanayagam, Joseph B., additional, Joseph, Majo X., additional, Thambar, Suku T., additional, Beltrame, John F., additional, Hillis, Graham S., additional, Thuaire, Christophe, additional, Dutoiu, Téodora, additional, Steg, Philippe Gabriel, additional, Juliard, Jean‐Michel, additional, Slama, Michel S., additional, El Mahmoud, Rami, additional, Nicollet, Eric, additional, Goube, Pascal, additional, Barone‐Rochette, Gilles, additional, Furber, Alain, additional, Bière, Loïc, additional, Laucevicius, Aleksandras, additional, Celutkiene, Jelena, additional, Kedhi, Elvin, additional, Timmer, Jorik, additional, Hermanides, Rik, additional, Kaplan, Eliza, additional, Riezebos, Robert K., additional, Samadi, Pouneh, additional, van Dongen, Elise, additional, Niehe, Sander R., additional, Suryapranata, Harry, additional, van Vugt, Stijn, additional, Ramos, Ruben, additional, Cacela, Duarte, additional, Santana, Ana, additional, Fiarresga, Antonio, additional, Sousa, Lidia, additional, Marques, Hugo, additional, Patricio, Lino, additional, Bernanrdes, Luis, additional, Rio, Pedro, additional, Carvalho, Ramiro, additional, Ferreira, Rui, additional, Silva, Tiago, additional, Rodrigues, Ines, additional, Modas, Pedro, additional, Portugal, Guilherme, additional, Fragata, Jose, additional, Pinto, Fausto J., additional, Menezes, Miguel Nobre, additional, Lopes, Guilhermina Cantinho, additional, Almeida, Ana Gomes, additional, Silva, Pedro Canas, additional, Nobre, Angelo, additional, Francisco, Ana Rita, additional, Ferreira, Nuno, additional, Lopes, Ricardo L., additional, Guzman, Luis, additional, Figal, Julio César, additional, Méndiz, Oscar, additional, Cortés, Claudia, additional, Favaloro, Roberto René, additional, Alvarez, Carlos, additional, Courtis, Javier, additional, Zeballos, Gabriela, additional, Schiavi, Lilia, additional, Rubio, Mariano, additional, Devlin, Gerard Patrick, additional, Fisher, Raewyn, additional, Stewart, Ralph Alan Huston, additional, White, Harvey Douglas, additional, Benatar, Jocelyne, additional, Kedev, Sasko, additional, Mitevska, Irena Peovska, additional, Kostovska, Elizabeta Srbinovska, additional, Pejkov, Hristo, additional, Eggers, Kai, additional, Frostfelt, Gunnar, additional, Johnston, Nina, additional, Olsowka, Maciej, additional, Åkerblom, Axel, additional, Soveri, Inga, additional, Aspberg, Johannes, additional, Sharir, Tali, additional, Elian, Dan, additional, Kerner, Arthur, additional, Massalha, Samia, additional, Fukuda, Keiichi, additional, Kohsaka, Shun, additional, Yasuda, Satoshi, additional, Nishimura, Shigeyuki, additional, Van de Werf, Frans, additional, Claes, Kathleen, additional, Hung, Chung‐Lieh, additional, Yun, Chun‐Ho, additional, Hou, Charles Jia‐Yin, additional, Kuo, Jen‐Yuan, additional, Yeh, Hung‐I, additional, Hung, Ta‐Chuan, additional, Li, Jiun‐Yi, additional, Chien, Chen‐Yen, additional, Tsai, Cheng‐Ting, additional, Liu, Chun‐Chieh, additional, Yu, Fa‐Chang, additional, Lin, Yueh‐Hung, additional, Lan, Wei‐Ren, additional, Yen, Chih‐Hsuan, additional, Tsai, Jui‐Peng, additional, Sung, Kuo‐Tzu, additional, Ntsekhe, Mpiko, additional, Pandie, Shaheen, additional, Viljoen, Charle A., additional, De Andrade, Marianne, additional, Moccetti, Tiziano, additional, Rossi, M. Grazia, additional, Abdelhamid, Magdy, additional, Adel, Ahmed, additional, Kamal, Ahmed, additional, Mahrous, Hossam, additional, El Kaffas, Sameh, additional, El Fishawy, Hussien, additional, Pop, Calin, additional, Claudia, Matei, additional, Popescu, Bogdan A., additional, Ginghina, Carmen, additional, Deleanu, Dan, additional, Iliescu, Vlad A., additional, Al‐Mallah, Mouaz H., additional, Aljzeeri, Ahmed, additional, Najm, Hani, additional, Alghamdi, Ali, additional, Ramos, Walter Enrique Mogrovejo, additional, Kuanprasert, Srun, additional, Prommintikul, Arintaya, additional, Nawarawong, Weerachai, additional, Woragidpoonpol, Surin, additional, Tepsuwan, Thitipong, additional, Taksaudom, Noppon, additional, Rimsukcharoenchai, Chataroon, additional, Euathrongchit, Juntima, additional, Wannasopha, Yutthaphan, additional, Yamwong, Sukit, additional, Sritara, Piyamitr, additional, Aramcharoen, Suthara, additional, Meemuk, Krissada, additional, Khairuddin, Ahmad, additional, Hadi, Hafidz Abd, additional, and Yahaya, Shaiful Azmi, additional
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- 2024
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11. International Prospective Registry of Acute Coronary Syndromes in Patients With COVID-19
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Kite, Thomas A., Ludman, Peter F., Gale, Chris P., Wu, Jianhua, Caixeta, Adriano, Mansourati, Jacques, Sabate, Manel, Jimenez-Quevedo, Pilar, Candilio, Luciano, Sadeghipour, Parham, Iniesta, Angel M., Hoole, Stephen P., Palmer, Nick, Ariza-Solé, Albert, Namitokov, Alim, Escutia-Cuevas, Hector H., Vincent, Flavien, Tica, Otilia, Ngunga, Mzee, Meray, Imad, Morrow, Andrew, Arefin, Md Minhaj, Lindsay, Steven, Kazamel, Ghada, Sharma, Vinoda, Saad, Aly, Sinagra, Gianfranco, Sanchez, Federico Ariel, Roik, Marek, Savonitto, Stefano, Vavlukis, Marija, Sangaraju, Shankar, Malik, Iqbal S., Kean, Sharon, Curzen, Nick, Berry, Colin, Stone, Gregg W., Gersh, Bernard J., and Gershlick, Anthony H.
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- 2021
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12. Trans-myocardial blood Interleukin-6 levels relate to intracoronary imaging defined features of plaque vulnerability and predict procedure-induced myocardial infarction
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Bambrough, Paul, Peverelli, Marta, Brown, Adam J., Giblett, Joel P., Bennett, Martin R., West, Nicholas E.J., and Hoole, Stephen P.
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- 2021
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13. Myocardial stress perfusion in asymptomatic patients: the silent ischemia makes the loudest sound
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Weir-McCall, Jonathan R. and Hoole, Stephen P.
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- 2021
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14. Endothelin-1 in Cardiac Allograft Vasculopathy
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Abraham, George Rahul, primary, Davenport, Anthony P., additional, and Hoole, Stephen P., additional
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- 2024
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15. Dapagliflozin in Myocardial Infarction without Diabetes or Heart Failure
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James, Stefan, primary, Erlinge, David, additional, Storey, Robert F., additional, McGuire, Darren K., additional, de Belder, Mark, additional, Eriksson, Niclas, additional, Andersen, Kasper, additional, Austin, David, additional, Arefalk, Gabriel, additional, Carrick, David, additional, Hofmann, Robin, additional, Hoole, Stephen P., additional, Jones, Daniel A., additional, Lee, Kelvin, additional, Tygesen, Hans, additional, Johansson, Peter A., additional, Langkilde, Anna Maria, additional, Ridderstråle, Wilhelm, additional, Parvaresh Rizi, Ehsan, additional, Deanfield, John, additional, and Oldgren, Jonas, additional
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- 2023
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16. GLP-1 vasodilatation in humans with coronary artery disease is not adenosine mediated
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Aetesam-ur-Rahman, Muhammad, Giblett, Joel P., Khialani, Bharat, Kyranis, Stephen, Clarke, Sophie J., Zhao, Tian X., Braganza, Denise M., Clarke, Sarah C., West, Nick E. J., Bennett, Martin R., and Hoole, Stephen P.
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- 2021
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17. Ascertainment of Silent Myocardial Infarction in Patients Undergoing Percutaneous Coronary Intervention (from the GLOBAL LEADERS Trial)
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Chang, Chun Chin, Spitzer, Ernest, Chichareon, Ply, Takahashi, Kuniaki, Modolo, Rodrigo, Kogame, Norihiro, Tomaniak, Mariusz, Komiyama, Hidenori, Yap, Sing-Chien, Hoole, Stephen P., Gori, Tommaso, Zaman, Azfar, Frey, Bernhard, Ferreira, Rui Cruz, Bertrand, Olivier F., Koh, Tian Hai, Sousa, Amanda, Moschovitis, Aris, van Geuns, Robert-Jan, Steg, Philippe Gabriel, Hamm, Christian, Jüni, Peter, Vranckx, Pascal, Valgimigli, Marco, Windecker, Stephan, Serruys, Patrick W., Soliman, Osama, and Onuma, Yoshinobu
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- 2019
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18. Cardiogenic Shock and Mechanical Circulatory Support
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Hoole, Stephen P., Vuylsteke, Alain, Myat, Aung, editor, Clarke, Sarah, editor, Curzen, Nick, editor, Windecker, Stephan, editor, and Gurbel, Paul A., editor
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- 2018
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19. DNA Damage and Repair in Patients With Coronary Artery Disease: Correlation With Plaque Morphology Using Optical Coherence Tomography (DECODE Study)
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Shah, Nikunj, Meira, Lisiane B., Elliott, Ruan M., Hoole, Stephen P., West, Nick E., Brown, Adam J., Bennett, Martin R., Garcia-Garcia, Hector M., Kuku, Kayode O., Dan, Kazuhiro, Kolm, Paul, Mariathas, Mark, Curzen, Nick, and Mahmoudi, Michael
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- 2019
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20. Glucagon-Like Peptide-1–Mediated Cardioprotection Does Not Reduce Right Ventricular Stunning and Cumulative Ischemic Dysfunction After Coronary Balloon Occlusion
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Giblett, Joel P., Axell, Richard G., White, Paul A., Aetesam-Ur-Rahman, Muhammad, Clarke, Sophie J., Figg, Nicola, Bennett, Martin R., West, Nick E.J., and Hoole, Stephen P.
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- 2019
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21. Long-Term Durability of Transcatheter Aortic Valve Prostheses
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Blackman, Daniel J., Saraf, Smriti, MacCarthy, Philip A., Myat, Aung, Anderson, Simon G., Malkin, Christopher J., Cunnington, Michael S., Somers, Kathryn, Brennan, Paul, Manoharan, Ganesh, Parker, Jessica, Aldalati, Omar, Brecker, Stephen J., Dowling, Cameron, Hoole, Stephen P., Dorman, Stephen, Mullen, Michael, Kennon, Simon, Jerrum, Melanie, Chandrala, Pavan, Roberts, David H., Tay, Justin, Doshi, Sagar N., Ludman, Peter F., Fairbairn, Timothy A., Crowe, Joanne, Levy, Richard D., Banning, Adrian P., Ruparelia, Neil, Spence, Mark S., and Hildick-Smith, David
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- 2019
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22. Effects of Acute GLP-1 Infusion on Pulmonary and Systemic Hemodynamics in Patients With Heart Failure: A Pilot Study
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Clarke, Sophie J., Pettit, Stephen, Giblett, Joel P., Zhao, Tian, Kydd, Anna C., Albrechtsen, Nicolai J.W., Deacon, Carolyn F., Parameshwar, Jayan, and Hoole, Stephen P.
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- 2019
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23. Investigation of the clinical application, mechanism and haemodynamic effects of remote ischaemic preconditioning in patients with coronary artery disease
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Hoole, Stephen P.
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616.1 - Published
- 2009
24. Effects of Patent Foramen Ovale Closure on Obstructive Sleep Apnea Syndrome: PCOSA Study
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Hoole, Stephen P., Hernández-Sánchez, Jules, Davies, William R., McNab, Duncan C., Calvert, Patrick A., Rana, Bushra S., Shapiro, Leonard M., and Davies, Michael G.
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- 2017
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25. Percutaneous Sampling of Local Biomolecule Gradients Across Coronary Artery Atherosclerotic Plaques
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West, Nick E.J., Corrigan, Joseph P., Owen, Richard H.G., Hoole, Stephen P., Brown, Adam J., Blatcher, Stephen, and Newby, Andrew C.
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- 2017
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26. Anatomical plaque and vessel characteristics are associated with hemodynamic indices including fractional flow reserve and coronary flow reserve: A prospective exploratory intravascular ultrasound analysis
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Brown, Adam J., Giblett, Joel P., Bennett, Martin R., West, Nick E.J., and Hoole, Stephen P.
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- 2017
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27. Balloon pulmonary angioplasty outcomes in patients previously treated by pulmonary endarterectomy surgery are inferior to those of inoperable patients
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Kirkby, Louise C., primary, Rodgers, Matthew S., additional, Amaral‐Almeida, Liliana, additional, Sheares, Karen, additional, Toshner, Mark, additional, Bunclark, Katherine, additional, Bartnik, Aleksandra, additional, Taboada, Dolores, additional, Ng, Choo, additional, Taghavi, Fouad J., additional, Tsui, Steven, additional, Cannon, John E., additional, Weir‐McCall, Jonathan R., additional, Coghlan, John G., additional, Jenkins, David P., additional, Pepke‐Zaba, Joanna, additional, and Hoole, Stephen P., additional
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- 2023
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28. Abstract 16759: In-Hospital Outcomes of Coronary Artery Bypass Grafting Candidates Undergoing Percutaneous Coronary Intervention During the Intensive Care Unit Restricted Covid-19 Pandemic: The Multi-Centre Prospective UK-REVASC Registry
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Kite, Thomas A, Owens, Colum, Chase, Alexander, Mozid, Abdul, Routledge, Helen, Hoole, Stephen P, Palmer, Nick, Egred, Mohaned, Perera, Divaka, Kyriacos, Mouyis, Sinha, Manas, Cahill, Tom, Candilio, Luciano, Anantharam, Brijesh, Murphy, Aengus, Farzin, Fath-Ordoubadi, Das, Paul, Morris, Paul, Curzen, Nick, Gorog, Diana, Hoye, Angela, Kean, Sharon, Ludman, Peter, Stone, Gregg W, Berry, Colin, and Gershlick, Anthony H
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- 2020
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29. Acute lung injury after balloon pulmonary angioplasty results in a similar haemodynamic response and possible clinical advantage at follow-up
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Rodgers, Matthew S, Kirkby, Louise C, Amaral-Almeida, Liliana, Sheares, Karen, Toshner, Mark, Taboada, Dolores, Ng, Choo, Cannon, John E, D'Errico, Luigia, Ruggiero, Alessandro, Screaton, Nicholas, Jenkins, David, Coghlan, John G, Pepke-Zaba, Joanna, Hoole, Stephen P, Rodgers, Matthew S [0000-0001-9485-2869], Hoole, Stephen P [0000-0002-3530-3808], and Apollo - University of Cambridge Repository
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RESEARCH ARTICLE ,balloon pulmonary angioplasty (BPA) ,chronic thromboembolic pulmonary hypertension (CTEPH) ,pulmonary vascular resistance (PVR) ,acute lung injury (ALI) ,mean pulmonary artery pressure (mPAP) ,RESEARCH ARTICLES - Abstract
Funder: None, Acute lung injury (ALI) is a common but poorly defined and understood complication of balloon pulmonary angioplasty (BPA) for chronic thromboembolic pulmonary hypertension (CTEPH). Little data are available on the medium term clinical outcomes of BPA complicated by ALI. We analyzed per-procedure data from 282 procedures in 109 patients and per-patient data from 85 patients. Serial right heart catheterization at baseline, after each BPA and at 3-month follow-up measured pulmonary vascular resistance (PVR), mean pulmonary artery pressure (mPAP), and cardiac output (CO). ALI (ALI+) was identified by chest radiography alone (ALIr+) or in association with hypoxia clinically (ALIcr+). Procedural predictors of ALI and patient outcomes at 3-months were compared no ALI (ALI-). ALI+ occurred in 17/282 (6.0%) procedures (ALIcr+: 2.5%, ALIr+: 3.5%). Prevailing haemodynamics (PVR: p < 0.01; mPAP: p < 0.05) at a procedural and patient level, as well as number of BPA sessions (p < 0.01), total number of vessels (p < 0.05), and occlusions (p < 0.05) treated at a patient level predicted ALI+. Those with ALI had greater percentage improvement in ΔCAMPHOR symptoms score (ALI+: -63.5 ± 35.7% (p < 0.05); ALIcr+: -84.4 ± 14.5% (p < 0.01); ALI-: -27.2 ± 74.2%) and ΔNT-proBNP (ALIcr+: -78.4 ± 11.9% (p < 0.01); ALI-: -42.9 ± 36.0%) at follow-up. There was no net significant difference in haemodynamic changes in ALI+ versus ALI- at follow-up. ALI is predicted by haemodynamic severity, number of vessels treated, number of BPA sessions, and treating occlusive disease. ALI in this cohort was associated with a clinical advantage at follow-up.
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- 2023
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30. Identification of a specific inflammatory protein biosignature in coronary and peripheral blood associated with increased risk of future cardiovascular events
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Proudfoot, Diane, primary, Gigante, Bruna, additional, West, Nick E.J., additional, Hoole, Stephen P., additional, Strawbridge, Rona J, additional, Tremoli, Elena, additional, Baldassarre, Damiano, additional, and Williams, Simon H., additional
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- 2023
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31. Interobserver Variability Between Expert, Experienced, and Novice Operator Affects Interpretation of Optical Coherence Tomography and 20 MHz Intravascular Ultrasound Imaging
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Martin, William G., primary, McNaughton, Edwina, additional, Bambrough, Paul B., additional, West, Nick E.J., additional, and Hoole, Stephen P., additional
- Published
- 2023
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32. Glucagon-Like Peptide-1: A Promising Agent for Cardioprotection During Myocardial Ischemia
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Giblett, Joel P., Clarke, Sophie J., Dutka, David P., and Hoole, Stephen P.
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- 2016
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33. Right ventricular-pulmonary artery coupling in chronic thromboembolic pulmonary hypertension
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Bartnik, Aleksandra, Pepke-Zaba, Joanna, Hoole, Stephen P, White, Paul, Garbi, Madalina, Coghlan, John G, Taghavi, Fouad, Tsui, Steven, Weir-McCall, Jonathan, Bartnik, Aleksandra [0000-0002-7628-8659], Garbi, Madalina [0000-0001-9520-8186], and Apollo - University of Cambridge Repository
- Subjects
cardiac catheterization ,Treatment Outcome ,pulmonary embolism ,Hypertension, Pulmonary ,Chronic Disease ,Ventricular Function, Right ,echocardiography ,Humans ,Heart ,Endarterectomy ,Pulmonary Artery ,Magnetic Resonance Imaging ,Angioplasty, Balloon - Abstract
Chronic thromboembolic pulmonary hypertension occurs in a proportion of patients with prior acute pulmonary embolism and is characterised by breathlessness, persistently raised pulmonary pressures and right heart failure. Surgical pulmonary endarterectomy (PEA) offers significant prognostic and symptomatic benefits for patients with proximal disease distribution. For those with inoperable disease, management options include balloon pulmonary angioplasty (BPA) and medical therapy. Current clinical practice relies on the evaluation of pulmonary haemodynamics to assess disease severity, timing of and response to treatment. However, pulmonary haemodynamics correlate poorly with patient symptoms, which are influenced by right ventricular tolerance of the increased afterload. How best to manage symptomatic patients with chronic thromboembolic pulmonary disease (CTEPD) in the absence of pulmonary hypertension is not resolved.Right ventricular-pulmonary artery coupling (RV-PAC) describes the energy transfer within the whole cardiopulmonary unit. Thus, it can identify the earliest signs of decompensation even before pulmonary hypertension is overt. Invasive measurement of coupling using pressure volume loop technology is well established in research settings. The development of efficient and less invasive measurement methods has revived interest in coupling as a viable clinical tool. Significant improvement in RV-PAC has been demonstrated after both PEA and BPA. Further studies are required to understand its clinical utility and prognostic value, in particular, its potential to guide management in patients with CTEPD. Finally, given the reported differences in coupling between sexes in pulmonary arterial hypertension, further work is required to understand the applicability of proposed thresholds for decoupling in therapeutic decision making.
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- 2023
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34. Mid-term clinical outcomes of ABSORB bioresorbable vascular scaffold implantation in a real-world population: A single-center experience
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Costopoulos, Charis, Crowson, Matthew C., Brown, Adam J., Braganza, Denise M., Bennett, Martin R., Hoole, Stephen P., and West, Nick E.J.
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- 2015
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35. Intravascular ultrasound of the proximal left anterior descending artery is sufficient to detect early cardiac allograft vasculopathy
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Floré, Vincent, Brown, Adam J., Pettit, Stephen J., West, Nick E. J., Lewis, Clive, Parameshwar, Jayan, and Hoole, Stephen P.
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- 2018
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36. Osteoarthritis in people over 16: diagnosis and management—updated summary of NICE guidance
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Wood, George, primary, Neilson, Julie, additional, Cottrell, Elizabeth, additional, and Hoole, Stephen P, additional
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- 2023
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37. Novel Approach for Assessing Postinfarct Myocardial Injury and Inflammation Using Hybrid Somatostatin Receptor Positron Emission Tomography/Magnetic Resonance Imaging
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Ćorović, Andrej, primary, Gopalan, Deepa, additional, Wall, Christopher, additional, Peverelli, Marta, additional, Hoole, Stephen P., additional, Calvert, Patrick A., additional, Manavaki, Roido, additional, Fryer, Tim D., additional, Aloj, Luigi, additional, Graves, Martin J., additional, Bennett, Martin R., additional, Rudd, James H.F., additional, and Tarkin, Jason M., additional
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- 2023
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38. Somatostatin Receptor PET/MR Imaging of Inflammation in Patients With Large Vessel Vasculitis and Atherosclerosis
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Ćorović, Andrej, primary, Wall, Christopher, additional, Nus, Meritxell, additional, Gopalan, Deepa, additional, Huang, Yuan, additional, Imaz, Maria, additional, Zulcinski, Michal, additional, Peverelli, Marta, additional, Uryga, Anna, additional, Lambert, Jordi, additional, Bressan, Dario, additional, Maughan, Robert T., additional, Pericleous, Charis, additional, Dubash, Suraiya, additional, Jordan, Natasha, additional, Jayne, David R., additional, Hoole, Stephen P., additional, Calvert, Patrick A., additional, Dean, Andrew F., additional, Rassl, Doris, additional, Barwick, Tara, additional, Iles, Mark, additional, Frontini, Mattia, additional, Hannon, Greg, additional, Manavaki, Roido, additional, Fryer, Tim D., additional, Aloj, Luigi, additional, Graves, Martin J., additional, Gilbert, Fiona J., additional, Dweck, Marc R., additional, Newby, David E., additional, Fayad, Zahi A., additional, Reynolds, Gary, additional, Morgan, Ann W., additional, Aboagye, Eric O., additional, Davenport, Anthony P., additional, Jørgensen, Helle F., additional, Mallat, Ziad, additional, Bennett, Martin R., additional, Peters, James E., additional, Rudd, James H.F., additional, Mason, Justin C., additional, and Tarkin, Jason M., additional
- Published
- 2023
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39. Pre-Treatment With Glucagon-Like Peptide-1 Protects Against Ischemic Left Ventricular Dysfunction and Stunning Without a Detected Difference in Myocardial Substrate Utilization
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McCormick, Liam M., Hoole, Stephen P., White, Paul A., Read, Philip A., Axell, Richard G., Clarke, Sophie J., O’Sullivan, Michael, West, Nick E.J., and Dutka, David P.
- Published
- 2015
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40. Right ventricular–pulmonary artery coupling in chronic thromboembolic pulmonary hypertension
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Bartnik, Aleksandra, primary, Pepke-Zaba, Joanna, additional, Hoole, Stephen P, additional, White, Paul, additional, Garbi, Madalina, additional, Coghlan, John G, additional, Taghavi, Fouad, additional, Tsui, Steven, additional, and Weir-McCall, Jonathan, additional
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- 2022
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41. Early disarticulation of a bioresorbable vascular scaffold: an underreported consequence of repeat imaging
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Giblett, Joel P., Brown, Adam J., Hoole, Stephen P., and West, Nick E. J.
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- 2018
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42. Low-dose interleukin 2 for the reduction of vascular inflammation in acute coronary syndromes (IVORY): protocol and study rationale for a randomised, double-blind, placebo-controlled, phase II clinical trial
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Sriranjan, Rouchelle, Zhao, Tian Xiao, Tarkin, Jason, Hubsch, Annette, Helmy, Joanna, Vamvaka, Evangelia, Jalaludeen, Navazh, Bond, Simon, Hoole, Stephen P, Knott, Philip, Buckenham, Samantha, Warnes, Victoria, Bird, Nick, Cheow, Heok, Templin, Heike, Cacciottolo, Paul, Rudd, James HF, Mallat, Ziad, Cheriyan, Joseph, Sriranjan, Rouchelle [0000-0002-9515-1201], Zhao, Tian Xiao [0000-0003-0202-5255], and Apollo - University of Cambridge Repository
- Subjects
Inflammation ,clinical trials ,Myocardial Infarction ,Myocardial Ischemia ,Coronary Artery Disease ,Atherosclerosis ,immunology ,C-Reactive Protein ,Clinical Trials, Phase II as Topic ,Glucose ,Treatment Outcome ,Double-Blind Method ,Fluorodeoxyglucose F18 ,cardiology ,Positron Emission Tomography Computed Tomography ,Humans ,Interleukin-2 ,cardiovascular imaging ,Acute Coronary Syndrome ,Randomized Controlled Trials as Topic - Abstract
Funder: Medical Research Council, Funder: British Heart Foundation, Funder: National Institute for Health Research (NIHR), INTRODUCTION: Inflammation plays a critical role in the pathogenesis of atherosclerosis, the leading cause of ischaemic heart disease (IHD). Studies in preclinical models have demonstrated that an increase in regulatory T cells (Tregs), which have a potent immune modulatory action, led to a regression of atherosclerosis. The Low-dose InterLeukin 2 (IL-2) in patients with stable ischaemic heart disease and Acute Coronary Syndromes (LILACS) study, established the safety of low-dose IL-2 and its biological efficacy in IHD. The IVORY trial is designed to assess the effects of low-dose IL-2 on vascular inflammation in patients with acute coronary syndromes (ACS). METHODS AND ANALYSIS: In this study, we hypothesise that low-dose IL-2 will reduce vascular inflammation in patients presenting with ACS. This is a double-blind, randomised, placebo-controlled, phase II clinical trial. Patients will be recruited across two centres, a district general hospital and a tertiary cardiac centre in Cambridge, UK. Sixty patients with ACS (unstable angina, non-ST elevation myocardial infarction or ST elevation myocardial infarction) with high-sensitivity C reactive protein (hsCRP) levels >2 mg/L will be randomised to receive either 1.5×106 IU of low-dose IL-2 or placebo (1:1). Dosing will commence within 14 days of admission. Dosing will comprise of an induction and a maintenance phase. 2-Deoxy-2-[fluorine-18] fluoro-D-glucose (18F-FDG) positron emission tomography/CT (PET/CT) scans will be performed before and after dosing. The primary endpoint is the change in mean maximum target to background ratios (TBRmax) in the index vessel between baseline and follow-up scans. Changes in circulating T-cell subsets will be measured as secondary endpoints of the study. The safety and tolerability of extended dosing with low-dose IL-2 in patients with ACS will be evaluated throughout the study. ETHICS AND DISSEMINATION: The Health Research Authority and Health and Care Research Wales, UK (19/YH/0171), approved the study. Written informed consent is required to participate in the trial. The results will be reported through peer-reviewed journals and conference presentations. TRIAL REGISTRATION NUMBER: NCT04241601.
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- 2022
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43. Cardioprotection for percutaneous coronary intervention — Reperfusion quality as well as quantity
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Giblett, Joel P., West, Nick E.J., and Hoole, Stephen P.
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- 2014
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44. Acute lung injury after balloon pulmonary angioplasty results in a similar haemodynamic response and possible clinical advantage at follow‐up
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Rodgers, Matthew S., primary, Kirkby, Louise C., additional, Amaral‐Almeida, Liliana, additional, Sheares, Karen, additional, Toshner, Mark, additional, Taboada, Dolores, additional, Ng, Choo, additional, Cannon, John E., additional, D'Errico, Luigia, additional, Ruggiero, Alessandro, additional, Screaton, Nicholas, additional, Jenkins, David, additional, Coghlan, John G., additional, Pepke‐Zaba, Joanna, additional, and Hoole, Stephen P., additional
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- 2022
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45. Low-doseinterleukin 2 for the reduction ofvascular inflammation in acute coronarysyndromes (IVORY): protocol and study rationale for a randomised, double-blind, placebo-controlled, phase II clinical trial
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Sriranjan, Rouchelle, primary, Zhao, Tian Xiao, additional, Tarkin, Jason, additional, Hubsch, Annette, additional, Helmy, Joanna, additional, Vamvaka, Evangelia, additional, Jalaludeen, Navazh, additional, Bond, Simon, additional, Hoole, Stephen P, additional, Knott, Philip, additional, Buckenham, Samantha, additional, Warnes, Victoria, additional, Bird, Nick, additional, Cheow, Heok, additional, Templin, Heike, additional, Cacciottolo, Paul, additional, Rudd, James H F, additional, Mallat, Ziad, additional, and Cheriyan, Joseph, additional
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- 2022
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46. Trans-myocardial Extraction of Endothelin-1 Correlates with Increased Microcirculatory Resistance following Percutaneous Coronary Intervention
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Abraham, George R., primary, Nyimanu, Duuamene, additional, Kuc, Rhoda E., additional, Maguire, Janet J., additional, Davenport, Anthony P., additional, and Hoole, Stephen P., additional
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- 2022
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47. Angina reduction after BRSs implantation: Correlation with changes in coronary hemodynamics
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West, Nick E.J., primary, Brown, Adam J., additional, and Hoole, Stephen P., additional
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- 2017
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48. Abstract 23088: GLP-1 Loading During Percutaneous Coronary Intervention (GOLD PCI) trial
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Giblett, Joel P, Clarke, Sophie, McCormick, Liam M, Zhao, Tian, Braganza, Denise, Densem, Cameron G, OʼSullivan, Michael, West, Nick E, and Hoole, Stephen P
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- 2017
49. Intravascular ultrasound and optical coherence tomography imaging of coronary atherosclerosis
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Costopoulos, Charis, Brown, Adam J., Teng, Zhongzhao, Hoole, Stephen P., West, Nick E. J., Samady, Habib, and Bennett, Martin R.
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- 2016
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50. Trans-Myocardial Blood Interleukin-6 Levels Relate to Intracoronary Imaging-Defined Features of Plaque Vulnerability and Predict Procedure-Induced Myocardial Infarction
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Bambrough, Paul, primary, Peverelli, Marta, additional, Brown, Adam J., additional, Giblett, Joel P., additional, Bennett, Martin R., additional, West, Nicholas E.J., additional, and Hoole, Stephen P., additional
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- 2022
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