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BACKGROUND Given newly debates on the association of birth-month with various diseases, we investigated the association of patients' birth-month with a burdensome lethal disease, ST-elevation myocardial infarction (STEMI). METHODS The data comes from an ongoing cohort-registry conducted on patients with STEMI registered to a mega cardiovascular hospital, in Western Iran (2016 - 2019). Baseline and follow-up data were collected using the European observational registry program (EORP) case report form, through interviewing eligible patients and reviewing their medical records. The quality of data as well as ethics considerations has been approved by EORP and Kermanshah University Medical Sciences (KUMS) Ethics Committees. RESULTS Among 2341 patients (81.5 % male) analysed, the peak of event [myocardial infarction (MI)] was 10 am followed by 8 pm. Their mean age (± SD) was 60.34 ± 12.40 years, minimum 19 years and maximum 96 years. March was significantly more frequent birth-month (16.4 %) (p < 0.001). Nevertheless, in terms of MI incidence, no significant variation was found between 12 months of a year, as well as the four seasons. The most common risk factors were smoking, hypertension, hypercholesterolemia and diabetes. About 3.8 % (n = 90) died in hospital (23 women). More than 6 % of patients expired during the first year of follow up. Although birth- month of 18.89 % (n = 17) of those expired was March, the difference was not significant (p = 0.025). CONCLUSIONS Among 12 months, March was highly significant common birth-month among patients with STEMI; however, this birth-month was not significantly associated with MI frequency of MI risk factors and/or a worse outcome. KEY WORDS Birth Month, Acute Myocardial Infarction, Heart Attack, Risk Factors, Outcomes

Background: Myocardial infarction in younger adults is an understudied research area. Objectives: This paper reports on characteristics, risk factors, and disease outcomes of young adults with St-elevation myocardial infarction (STEMI).Methods: This is a sub-analysis of data from the Kermanshah Acute Coronary Syndrome Registry, including all patients aged ≤45 with STEMI (n=247) registered in the registry from June 2017 to June 2019. Results: Patients aged ≤45 constituted 10.66% of all patients with STEM; the majority was male (91.8%), and the most common CVD risk factors included: smoking (56.7%), low high-density lipoprotein (55.5%), elevated triglyceride (44.4%), hypertension (38.2%), hypercholesterolemia (38.1%), elevated low-density lipoprotein (26.3%), and obesity (24.3%). Many patients (62.8%) received primary percutaneous coronary intervention (PCI), and in-hospital mortality was low at 0.8%. Conclusions: Younger adults should be screened for CVD risk factors, and are educated and supported to participate in programs that aim to reduce risk through risk factor modification.

Analyzing child mortality, an important indicator of health and development of countries, can help policymakers to develop health programs that resulted in improving Childs’s health. Recognizing the causes of in-hospital deaths also assists health caregivers to revise their medical services. The aim of this study was to explore the causes of death in the largest hospital in western Iran. This retrospective descriptiveanalytical study was conducted in Imam Reza Hospital (IRH) in Kermanshah, data including demographic characteristics (e.g., age), medical information, and causes of death of patients aged ≤18 years, from April 2012 to March 2017 were collected using a checklist. The causes of mortalities were categorized based on the International Coding of Diseases (ICD, Version 10). Using logistic regression, Chi-square, and Cramer's V test in SPSS, the relationships between the outcome and predicting variables were assessed. The results showed 1113 deaths among 21,247 people≤, 18 years people admitted to IRH for five years. About 55% were female and 74% neonate, with a dropping trend from 2011 (4.62%) to 2016 (4.00%). Medical records, mostly, used a variety of usual medical terms for the causes of death, rather than using ICD10 categories. Data were analyzed after alternating medical terms and re-coding data using ICD10. Respiratory system diseases by 34% (dominancy of hyaline membrane diseases), infectious diseases by 28% (leading by sepsis), and diseases of the blood by 13% (mostly disseminated intravascular coagulation (DIC)), respectively, were the most common causes of death. Age was the most important associated factor for all-cause mortality associated with infectious diseases and respiratory system diseases (P=0.01). Having a significant number of neonatal mortality, paying more attention to the neonatal, prenatal, and antenatal care is recommended. In addition, the fatality of infectious diseases is concerning and needs paying serious attention to the health care system.

Introduction: A disease/patients’ registry, is a collection of secondary data related to those with particular condition/disease/procedure. Patients registries not only provide health providers and patients with reminders to check certain examinations in order to achieve certain quality goals, but their main role is associated to health research either as a database for clinical studies in a particular disease or (preferably) as a comprehensive cohort study by itself. The aim of this study is to summarize information published electronically about patients’ registries. Methods: This short report is resulted from reviewing the electronic databases and websites aiming to collect valid and comprehensive information in regard to the background and frequency of patients’ registries worldwide. In addition, using the terms “patients’ registries vs cohort studies”, “patients’ registry vs observational study”, “patients’ registry vs medical records” the variety, advantages and disadvantages of patients’ registries were searched for. Results: The results showed that a long list of disease registries from Europe, United States of America (USA) and Asian countries were detailed in publication. Formal disease registries have been given more attention from 1960, in which cancer registries were highlighted, however the absolute origin for patients’ registries is not realized precisely. More than 5o patients’ registries from USA only, have been introduced. The obtained information was mostly about registries at national or international levels and hence they were not including many local registries within the limited geographic area. Rare conditions (e.g., Usher Syndrome Registry) and chronic diseases (e.g., Alzheimer’s Prevention Registry) are the most common cases that have systematically been registered. Conclusion: A wide range of disease registration methods from sophisticated and complex databases to simple spreadsheets accessible for only a small group of physicians working in local health care centers, have been developed worldwide, however the more developed the country, the more diseases registry organizations there are. In other words, disease registries require human resources as well as fundamental constructions and amenities. Considering the advantages and benefits of disease registries, we recommend developing disease registries widely in our country, using the prepared and developed software and questionnaires from other countries.