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This study was conducted to evaluate the effects of different levels of prebiotic GroBiotic®-A on some growth, hematological, biochemical and immunity parameters of cultured juvenile beluga (Hous huso). Four groups of beluga sturgeon with mean weight of 40.82± 5.8 g were raised for 56 days in fiberglass tanks (20 fish to each tank) and fed with different levels of GroBiotic®-A with concentrations of 0, 0.5, 1.0 and 2.0% (three replicates were used for each concentration). At the end of trial, some of the growth parameters were calculated and blood samples collected from 36 fish. Then some hematological, biochemical and immunity parameters in different groups were determined and compared with control group. Results showed that significant difference in some growth parameters, neutrophil percentage, haemoglobin (Hb), haematocrit (Hct) value and total protein (TP) in fish fed with 2.0% GroBiotic®-A were observed compared with control group (p<0.05), but no significant difference were observed in other hematological and biochemical parameters (p>0.05). The results suggest that administration of GroBiotic®-A at the level of 2.0% will be improvement some of the growth and hematological parameters and immune function of juvenile beluga. So, using of this supplement as growth promotor and immunostimulants was recommended in farmed beluga. [ABSTRACT FROM AUTHOR]