1. Mammary analog secretory carcinoma of the parotid gland: A case of a 12-year-old Taiwanese girl
- Author
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Lung-Che Chen, Hsin-Te Hsu, Yen-Chun Chen, Yun-Ho Lin, and Ya-Fang Lin
- Subjects
Pathology ,medicine.medical_specialty ,Salivary gland ,business.industry ,media_common.quotation_subject ,medicine.disease ,Acinic cell carcinoma ,Parotid gland ,Fusion gene ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,stomatognathic system ,Mucoepidermoid carcinoma ,030220 oncology & carcinogenesis ,medicine ,Neoplasm ,Lymph ,Girl ,030223 otorhinolaryngology ,business ,media_common - Abstract
Mammary analog secretory carcinoma (MASC) is a recently identified neoplasm of the salivary glands, which harbors the distinctive ETV6-NTRK3 oncogenic fusion gene from other salivary malignant tumors. MASC shares morphologic characteristics with acinic cell carcinoma (AciCC) and mucoepidermoid carcinoma (MEC), and is more likely to metastasize to the regional lymph nodes. Thus differentiation among other salivary gland tumors is important. We present a rare pediatric case of parotid gland MASC in a 12-year-old girl and a review of world literature.
- Published
- 2018