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2. Electrostatic focusing of cold and heavy molecules for the ACME electron EDM search

Author

Wu, Xing, Hu, Peiran, Han, Zhen, Ang, Daniel G., Meisenhelder, Cole, Gabrielse, Gerald, Doyle, John M., and DeMille, David

Subjects
Physics - Atomic Physics, High Energy Physics - Experiment, Quantum Physics
Abstract

The current best upper limit for electron electric dipole moment (EDM), $|d_e|<1.1\times10^{-29}\,$e$\cdot$cm ($90$% confidence), was set by the ACME collaboration in 2018. The ACME experiment uses a spin-precession measurement in a cold beam of ThO molecules to detect $d_e$. An improvement in statistical uncertainty would be possible with more efficient use of molecules from the cryogenic buffer gas beam source. Here, we demonstrate electrostatic focusing of the ThO beam with a hexapole lens. This results in a factor of $16$ enhancement in the molecular flux detectable downstream, in a beamline similar to that built for the next generation of ACME. We also demonstrate an upgraded rotational cooling scheme that increases the ground state population by $3.5$ times compared to no cooling, consistent with expectations and a factor of $1.4$ larger than previously in ACME. When combined with other demonstrated improvements, we project over an order of magnitude improvement in statistical sensitivity for the next generation ACME electron EDM search., Comment: 20 pages, 8 figures, 2 pages appendices

Published
2022
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4. Electrostatic focusing of cold and heavy molecules for the ACME electron EDM search

Author

Wu, Xing, primary, Ang, Daniel, primary, DeMille, David, primary, Doyle, John, primary, Gabrielse, Gerald, primary, Han, Zhen, primary, Hao, Bingjie, primary, Hiramoto, Ayami, primary, Hu, Peiran, primary, R. Hutzler, Nicholas, primary, Lascar, Daniel, primary, Lasner, Zack, primary, Liu, Siyuan, primary, Masuda, Takahiko, primary, Meisenhelder, Cole, primary, Mitchell, John, primary, Daniel Panda, Cristian, primary, Sasao, Noboru, primary, Uetake, Satoshi, primary, and Yoshimura, Koji, primary

Published
2022
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5. Experimental Upgrades For Improving Statistical And Systematic Uncertainties In ACME III

Author

Hu, Peiran, primary, Han, Zhen, primary, Diver, Collin, primary, Watts, Maya, primary, Ang, Daniel, primary, DeMille, David, primary, Doyle, John, primary, Gabrielse, Gerald, primary, Hiramoto, Ayami, primary, R. Hutzler, Nicholas, primary, Lascar, Daniel, primary, Lasner, Zack, primary, Liu, Siyuan, primary, Masuda, Takahiko, primary, Meisenhelder, Cole, primary, Mitchell, John, primary, Daniel Panda, Cristian, primary, Sasao, Noboru, primary, Uetake, Satoshi, primary, Wu, Xing, primary, and Yoshimura, Koji, primary

Published
2022
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6. Performance of a silicon photomultiplier module for the ACME III electron EDM search

Author

Hiramoto, Ayami, primary, Ang, Daniel, primary, DeMille, David, primary, Diver, Collin, primary, Doyle, John, primary, Gabrielse, Gerald, primary, Han, Zhen, primary, Hu, Peiran, primary, R. Hutzler, Nicholas, primary, Lascar, Daniel, primary, Liu, Siyuan, primary, Masuda, Takahiko, primary, Meisenhelder, Cole, primary, Mitchell, John, primary, Daniel Panda, Cristian, primary, Sasao, Noboru, primary, Uetake, Satoshi, primary, Watts, Maya, primary, Wu, Xing, primary, and Yoshimura, Koji, primary

Published
2022
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7. Progress in the ACME III Search for the Electron EDM

Author

Ang, Daniel, primary, Meisenhelder, Cole, primary, DeMille, David, primary, Diver, Collin, primary, Doyle, John, primary, Han, Zhen, primary, Hiramoto, Ayami, primary, Hu, Peiran, primary, R. Hutzler, Nicholas, primary, Lascar, Daniel, primary, Lasner, Zack, primary, Liu, Siyuan, primary, Masuda, Takahiko, primary, Mitchell, John, primary, Daniel Panda, Cristian, primary, Sasao, Noboru, primary, Uetake, Satoshi, primary, Watts, Maya, primary, Wu, Xing, primary, Yoshimura, Koji, primary, and Gabrielse, Gerald, primary

Published
2022
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14. [Reproductive Health-Oriented Development in Assisted Reproductive Technologies].

Author

Hu P, Pan J, Liu X, and Huang H

Subjects
Humans, Female, Reproductive Health, Fertilization in Vitro methods, Sperm Injections, Intracytoplasmic, Embryo Transfer methods, Infertility etiology, Infertility therapy, Preimplantation Diagnosis, Pregnancy, Reproductive Techniques, Assisted adverse effects
Abstract

Assisted reproductive technologies (ARTs) are core components of the field of reproductive medicine, encompassing multiple pivotal stages of early development from gamete maturation and fertilization to embryo development. Against the backdrop of a deteriorating trend of global decline in fertility rates, patients with infertility problems increasingly turn to ARTs to realize their dreams of parenthood. However, concomitant with this trend is a growing apprehension regarding the potential adverse effects of ARTs. Herein, we endeavor to discuss several common ARTs procedures utilized in clinical settings and the relevant cutting-edge advancements. The ARTs discussed in the article include in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), biphasic in vitro maturation (biphasic IVM), frozen embryo transfer (FET), preimplantation genetic testing (PGT), non-invasive PGT (niPGT), etc. In addition, we reevaluated their roles within the broader context of assisted reproduction aimed at promoting reproductive health. Additionally, we will delve into the impact of ARTs on the reproductive health of the offspring. By prioritizing the reproductive well-being of both patients and their offspring, the ongoing development and improvement of ARTs to enhance their efficacy and safety will contribute significantly to the advancement of human reproductive health., Competing Interests: 利益冲突　所有作者均声明不存在利益冲突, (© 2024《四川大学学报（医学版）》编辑部 版权所有Copyright ©2024 Editorial Office of Journal of Sichuan University (Medical Sciences).)

Published
2024
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