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Dichlorodifluoromethane (CFC‐12) is an ozone‐depleting substance and potent greenhouse gas, which was required to be phased out after 2010 under the Montreal Protocol. CFC‐12 emissions need to be quantitatively traced. However, estimates of CFC‐12 emissions in China based on atmospheric inversions are unavailable after 2010. Here, using atmospheric observations at nine sites across China and inversion techniques, we quantify CFC‐12 emissions in China during 2011–2020 (on average 11.0 ± 0.6 Gg yr−1). The emissions derived from observations are 8.5 times larger than the previously reported inventories. Apart from emissions from eastern China revealed in previous studies, this study reveals that 71% of national total emissions were from other parts of China. Moreover, this study reconciled the global CFC‐12 emissions during 2011–2020: 28% were traced to China by this study, 9% of emissions were traced in previous studies, while 63% remain untraced, indicating the need for more regional emission inversion studies. Plain Language Summary: Chlorofluorocarbons (CFCs), well known as Freon, are damaging to the stratospheric ozone layer and are potent greenhouse gases. Dichlorodifluoromethane (CFC‐12; CCl2F2) is one of the major CFCs. The production and consumption of CFC‐12 are controlled under the regulations of the Montreal Protocol and have been phased out globally since 2010. As the largest developing country and once a major producer and consumer of CFC‐12, CFC‐12 emissions in China are of great interest. In this study, we quantified emissions of CFC‐12 in China during 2011–2020 based on atmospheric observations in a network of nine sites across China. We find that the emissions derived from atmospheric inversion are 8.5 times larger than the previous emission inventories estimated using production and consumption information, suggesting unaccounted‐for emissions occurring in China. Apart from emissions from eastern China revealed in previous studies, this study reveals that 71% of national total emissions were from other parts of China. The Chinese emissions of CFC‐12 accounted for 28% of global totals from 2011 to 2020. However, there is a big gap between the total CFC‐12 emission from China, western Europe, Australia, the United States, India, and global totals, suggesting that more regional atmospheric inversion estimates are encouraged. Key Points: China's Dichlorodifluoromethane (CFC‐12) emissions during 2011–2020 were quantified using atmospheric observations at nine sites across China and inverse modelingA quantitative depiction of spatial CFC‐12 emissions across China was provided by this study28% of global CFC‐12 emissions for 2011–2020 occurred in China, according to this study [ABSTRACT FROM AUTHOR]

In interstellar environment, fullerene species readily react with large molecules (e.g. polycyclic aromatic hydrocarbons, PAHs and their derivatives) in the gas phase, which may be the formation route of carbon dust grains in space. In this work, the gas-phase ion–molecule collision reaction between fullerene cations (⁠|${\rm C}_{n}\, ^+$|⁠ , n  = 32, 34,..., 60) and functionalized PAH molecules (9-hydroxyfluorene, C13H10O) are investigated both experimentally and theoretically. The experimental results show that fullerene/9-hydroxyfluorene cluster cations are efficiently formed, leading to a series of large fullerene/9-hydroxyfluorene cluster cations (e.g. [(C13H10O)C60]+, [(C13H10O)3C58]+, and [(C26H18O)(C13H10O)2C48]+). The binding energies and optimized structures of typical fullerene/9-hydroxyfluorene cluster cations were calculated. The bonding ability plays a decisive role in the cluster formation processes. The reaction surfaces, modes, and combination reaction sites can result in different binding energies, which represent the relative chemical reactivity. Therefore, the geometry and composition of fullerene/9-hydroxyfluorene cluster cations are complicated. In addition, there is an enhanced chemical reactivity for smaller fullerene cations, which is mainly attributed to the newly formed deformed carbon rings (e.g. 7 C-ring). As part of the co-evolution network of interstellar fullerene chemistry, our results suggest that ion–molecule collision reactions contribute to the formation of various fullerene/9-hydroxyfluorene cluster cations in the interstellar medium, providing insights into different chemical reactivity caused by oxygenated functional groups (e.g. hydroxyl, OH, or ether, C-O-C) on the cluster formations. [ABSTRACT FROM AUTHOR]

To investigate the gas-phase hydrogenation processes of large, astronomically relevant cationic polycyclic aromatic hydrocarbon (PAH) molecules under the interstellar environments, the ion–molecule collision reaction between six PAH cations and H-atoms is studied. The experimental results show that the hydrogenated PAH cations are efficiently formed, and no even–odd hydrogenated mass patterns are observed in the hydrogenation processes. The structure of newly formed hydrogenated PAH cations and the bonding energy for the hydrogenation reaction pathways are investigated with quantum theoretical calculations. The exothermic energy for each reaction pathway is relatively high, and the competition between hydrogenation and dehydrogenation is confirmed. From the theoretical calculation, the bonding ability plays an important role in the gas-phase hydrogenation processes. The factors that affect the hydrogenation chemical reactivity are discussed, including the effect of carbon skeleton structure, the side-edged structure, the molecular size, the five- and six-membered C-ring structure, the bay region structure, and the neighbouring hydrogenation. The infrared spectra of hydrogenated PAH cations are also calculated. These results we obtain once again validate the complexity of hydrogenated PAH molecules, and provide the direction for the simulations and observations under the co-evolution interstellar chemistry network. We infer that if we do not consider other chemical evolution processes (e.g. photoevolution), then the hydrogenation states and forms of PAH compounds are intricate and complex in the interstellar medium. [ABSTRACT FROM AUTHOR]

The purpose of this study was to replicate previous research that examined the effects of tact and listener instruction on the emergence of bidirectional intraverbals, and to extend this research line to include teaching a foreign language to students with autism spectrum disorders (ASD) via telehealth. The study participants were four Chinese native primary school‐aged students. An adaptive alternative treatment design was used to compare the effects of tact and listener instruction on bidirectional intraverbals, and pre‐probe and post‐probe data demonstrated that both forms of instruction led to bidirectional intraverbal relations, with tact instruction being relatively more effective. Maintenance and social validity were assessed for all participants, and booster instructions were provided as needed. The results were discussed in the context of inclusive education and improving foreign language instruction for students with special needs. [ABSTRACT FROM AUTHOR]

Venous thromboembolism (VTE) is a multifactorial disease, and pulmonary hypertension (PH) is a serious condition characterized by pulmonary vascular remodeling leading with increased pulmonary vascular resistance, ultimately leading to right heart failure and death. Although VTE and PH have distinct primary etiologies, they share some pathophysiologic similarities such as dysfunctional vasculature and thrombosis. In both conditions there is solid evidence that EVs derived from a variety of cell types including platelets, monocytes, endothelial cells and smooth muscle cells contribute to vascular endothelial dysfunction, inflammation, thrombosis, cellular activation and communications. However, the roles and importance of EVs substantially differ between studies depending on experimental conditions and parent cell origins of EVs that modify the nature of their cargo. Numerous studies have confirmed that EVs contribute to the pathophysiology of VTE and PH and increased levels of various EVs in relation with the severity of VTE and PH, confirming its potential pathophysiological role and its utility as a biomarker of disease severity and as potential therapeutic targets. [ABSTRACT FROM AUTHOR]

Organoids, three-dimensional structures cultured in vitro, can recapitulate the microenvironment, complex architecture, and cellular functions of in vivo organs or tissues. In recent decades, liver organoids have been developed rapidly, and their applications in biomedicine, such as drug screening, disease modeling, and regenerative medicine, have been widely recognized. However, the lack of repeatability and consistency, including the lack of standardized culture conditions, has been a major obstacle to the development and clinical application of liver organoids. It is time-consuming for researchers to identify an appropriate medium component scheme, and the usage of some ingredients remains controversial. In this review, we summarized and compared different methods for liver organoid cultivation that have been published in recent years, focusing on controversial medium components and discussing their advantages and drawbacks. We aimed to provide an effective reference for the development and standardization of liver organoid cultivation. [ABSTRACT FROM AUTHOR]

Valorization of biomass-derived feedstocks for the supply of high-value chemicals, clean fuel and electricity is gaining importance in the context of the circular economy. In particular, raw chemicals can be produced by electrocatalytic, photocatalytic and photoelectrochemical oxidation of glycerol, a by-product of biodiesel manufacturing. Nonetheless, controlling the selectivity of the oxidation of glycerol, a C3 compound, is challenging. Indeed, a wide range of C1 to C3 products containing carbonyl or carboxyl groups are produced, thus limiting the development of catalytic glycerol transformation. Here, we review electrooxidation, photooxidation and photoelectrooxidation of glycerol with emphasis on sustainability, and selectivity in catalytic systems. We also discuss co-electrolysis and fuel cells that present promising strategies involving glycerol oxidation. [ABSTRACT FROM AUTHOR]

Fullerene molecules are affected and constrained by different interstellar environmental factors, such as UV radiation, atoms, and other coexisting molecules. To understand the coevolution of the interstellar fullerene chemistry, by tracking the accretion processes on fullerene cations, we present an investigation of the chemical reactivity of fullerene (C60) cations and smaller fullerene (C54/56/58) cations with hydrogen and C14H10 in the gas phase. Experiments are performed using a quadrupole ion trap in combination with time-of-flight mass spectrometry. The experimental results show hydrogenated fullerene-C14H10 cluster cations (i.e. [H n C60(C14H10) m ]+ and [H n C54/56/58(C14H10) m ]+) are efficiently formed through ion-molecule collision reaction. H-atoms are more likely to accumulate on the surface of fullerenes than C14H10; not only does hydrogen more easily form a covalent bond, the later accreted hydrogen will also expel the already accreted C14H10. Through theoretical calculations, we obtain the structure of newly formed clusters (e.g. [HC60(C14H10)]+ and [HC58(C14H10)]+) and the binding energies of their reaction pathways, together with IR spectra. The bonding ability plays a decisive role in the ternary cluster formation processes, and the existence of occupation and expulsion competitive reaction channels in the accretion processes on fullerene surfaces is confirmed. As part of the coevolution of the interstellar chemistry, the occupation and expulsion reaction modes should be considered when fullerenes further react with H-atoms and PAHs. As a result, the molecular structures of hydrogen/fullerene/PAH clusters are diverse, and hydrogenated-fullerene-related clusters (e.g. hydrogenated fullerenes or hydrogenated fullerenes-PAHs) have a higher distribution than non-hydrogenated-fullerene-related clusters (e.g. fullerenes or fullerenes-PAHs) in the interstellar environment. [ABSTRACT FROM AUTHOR]

Food stealing is often a serious behavioral problem among children with diagnoses of autism and other developmental disorders. Very few empirical studies concerning this behavioral challenge have been reported. We applied a correspondence training procedure to teach self‐control as replacement behavior to four children with autism and developmental disorders who displayed food stealing in the community. A changing criterion design embedded within a nonconcurrent multiple‐probe across participants design was used. The treatment succeeded for all four participants by increasing latency to eating highly preferred food to a predetermined criterion and reducing occurrences of food stealing to zero. Three participants generalized the replacement behavior to natural settings and maintained the behavior for 2 weeks, 1 month, 2 months, 3 months, and 4 months. One participant without expressive language was taught successfully during treatment trials but failed to maintain and generalize the behavior. A functional relation between delaying food eating and Say‐Do correspondence training was demonstrated. [ABSTRACT FROM AUTHOR]

Reflectance spectroscopy is a powerful tool to remotely identify the mineral and chemical compositions of the lunar regolith. The lunar soils contain silicate minerals with prominent absorption features and glasses with much less distinctive spectral features. The accuracy of mineral abundance retrieval may be affected by the presence of glasses. In this work, we construct a spectral library of mixtures of major lunar-type minerals and synthetic glasses with varying relative abundances and test their performance on mineral abundance retrievals. By matching the library spectra with the spectra of mineral mixtures with known abundances, we found that the accuracy of mineral abundance retrieval can be improved by including glass as an endmember. Although our method cannot identify the abundance of glasses quantitatively, the presence or absence of glasses in the mixtures can be decisively determined. [ABSTRACT FROM AUTHOR]

In China, there is an increasing demand for preschool children with autism spectrum disorder (ASD) enrolled in general education to learn English vocabulary. The purpose of this study was to evaluate the effect of foreign mand training in English on the acquisition of mand responses, and the emergence of tact and listener responses for three Chinese‐speaking preschool children (boys; 4–5 years of age) with ASD. Echoic‐to‐mand training was implemented to teach mands in English. The study employed a concurrent multiple‐probe design across behaviors. The results of the study indicated that the training was effective in the acquisition of mand responses. Moreover, untaught tacts and listener responses for the same vocabulary emerged without explicit training. Implications for small‐group mand training in foreign language acquisition were discussed. [ABSTRACT FROM AUTHOR]

The purpose of the study was to examine the effects of an instructional sequence involving simple tact, category tact, and match-to-sample instructions on the emergence of metaphorical extensions about emotions for children with autism spectrum disorder. Three Chinese children (1 girl, 2 boys, 7–8 years old) with autism spectrum disorder participated. Results indicate that the participants' intraverbal responses for metaphorical extensions about emotions emerged or increased without direct training after completion of the instructional sequence to which verbal instruction had been added. All three children maintained the metaphorical extensions about emotions for 4 weeks. [ABSTRACT FROM AUTHOR]

Objective: The purpose of this study was to explore the clinical applications of high-throughput sequencing (HTS) in the identification of pathogens in patients with urinary tract infection (UTI), peritoneal dialysis-associated peritonitis (PDAP), central venous catheter related blood infections (CRBIs), and lung infections in the nephrology department. Methods: Midstream urine samples from 112 patients with UTI, peritoneal fluid samples from 67 patients with PDAP, blood samples from 15 patients with CRBI, and sputum specimens from 53 patients with lung infection were collected. The HTS and ordinary culture methods were carried out in parallel to identify the pathogens in each sample. Pathogen detection positive rate and efficacy were compared between the two methods. Results: The pathogen positive detection rates of HTS in UTI, PDAP, CRBI, and lung infection were strikingly higher than those of the culture method (84.8% vs. 35.7, 71.6% vs. 23.9%, 75% vs. 46.7%, 84.9% vs. 5.7%, p < 0.05, respectively). HTS was superior to the culture method in the sensitivity of detecting bacteria, fungi, atypical pathogens, and mixed microorganisms in those infections. In patients who had empirically used antibiotics before the test being conducted, HTS still exhibited a considerably higher positive rate than the culture method (81.6% vs. 39.0%, 68.1% vs. 14.9%, 72.7% vs. 36.4%, 83.3% vs. 4.2%, p < 0.05, respectively). Conclusions: HTS is remarkably more efficient than the culture method in detecting pathogens in diverse infectious diseases in nephrology, and is particularly potential in identifying the pathogens that are unable to be identified by the common culture method, such as in cases of complex infection with specific pathogens or subclinical infection due to preemptive use of antibiotics. [ABSTRACT FROM AUTHOR]

The objective of the current study was to assess how a LEGO intervention, implemented by a grandparent and a parent at home, affected social interactions for four children (two girls, two boys; ages 6–7 years) on the autism spectrum in China. A multiple probe design across four families was used. Grandparents and parents were trained to use effective teaching strategies in structured LEGO play activities to engage in interactions with their children. Results indicated that all four children’s spontaneous social initiations and responses were improved and maintained for at least 7 weeks following completion of the intervention. Increased social initiations and responses were generalized to family activities and free play at home. [ABSTRACT FROM AUTHOR]

Schools must accurately implement effective interventions targeting deficits and/or learning challenges for secondary school‐aged students with disabilities to fulfill their responsibility of preparing students for life after high school. School psychologists supporting this mission may be frustrated by the limited research conducted with secondary students. This study is designed to describe the evidence base for interventions used with secondary school students by relying on N = 1 research design studies. N = 1 research design can establish a functional relationship between the independent and dependent variable(s) and allows for the complexity of real world intervention implementation as experienced by practicing school psychologists, making N = 1 an ideal research base on which to make practical decisions in secondary schools. Although interventions increased secondary school‐aged students' performance across studies, not enough well‐designed studies were conducted across research groups for any specific intervention (i.e., meeting the minimum criteria established by What Works Clearinghouse) at the secondary school level. As a result, school psychologists will need to rely heavily on their professional judgment when combining the best available evidence with client and contextual variables to make individualized decisions for secondary school students. An application of this evidence‐based practice decision‐making model for a secondary student is provided. [ABSTRACT FROM AUTHOR]

Stereo‐dependent properties of E‐ and Z‐HFO‐1234ze were investigated by density functional theory, extrapolated complete basis set limit, explicitly correlation, and symmetry‐adapted perturbation theory together with molecular dynamics simulations. The enthalpy of isomerization of E‐HFO‐1234ze to the Z isomer is 9.7 kJ/mol, showing the reverse cis effect. The HFO‐1234ze molecules interact predominantly via π‐π stacking of the double bonds and hydrogen bonding of CH⋯F. Although the E‐dimers involve less steric exchange‐repulsion, their binding energies are generally smaller by 2–6 kJ/mol than the Z‐dimers, in which the Coulombic multipole–multipole‐type electrostatic interactions and the long‐range dispersions are more profound. Local ordering in liquid occurs primarily via π stacking of the CHF‐end. The significant difference in boiling points of E‐ and Z‐HFO‐1234ze is clarified in terms of the dimerization free energy. Self‐diffusion coefficients and dielectric constants of HFO‐1234ze depend strongly on the E‐ and Z‐conformations. [ABSTRACT FROM AUTHOR]

Bidirectional naming is an important ability which enables children to acquire listener and speaker behaviors through exposure to relevant word-object associations. Many children with autism spectrum disorder (ASD) or developmental delays do not demonstrate this ability and require systematic instruction. The purpose of the present study was to evaluate the efficacy of computer-assisted multiple exemplar instruction to facilitate bidirectional naming. Three 5-year-old Chinese boys with ASD participated in a multiple probe across three participants design. The results indicated that all three children's naming performance increased from pretest to posttest, supporting the potential practicality of the instructional system for use in applied settings. [ABSTRACT FROM AUTHOR]

Many children with autism spectrum disorder (ASD) do not have symbolic play skills. One type of symbolic play involves playing with imaginary objects, in which a child displays play actions without actual objects. The purpose of this study was to evaluate the effects of video modeling on the acquisition, maintenance, and generalization of playing with imaginary objects in young children with ASD. Three male Chinese children (aged 4–5 years) with ASD participated in this study. A multiple-probe across three behaviors design was used. The results indicated that video modeling was effective in establishing and maintaining target symbolic play behaviors for the three children. Generalization to untaught imaginary play activities occurred in all three children. [ABSTRACT FROM AUTHOR]

This study evaluated the effects of using preferred activities with peer support on the social interactions of preschoolers with autism spectrum disorder (ASD) and their typically developing peers. Two preschool-age children with ASD and six peers in an inclusive classroom participated in this study. A multiple-probe single case experimental design across three peers was employed. Results indicated that the participants' social initiations and responses, as well as the percentage of time engaged in social play, increased following the preferred activity. Gains were also demonstrated across social interactions and time engaged in the preferred activity plus peer support condition. Increases in social interaction behaviors in typically developing peers were also observed, and positive intervention gains were maintained during 5-week follow-up sessions. Implications for research and practice for improving interaction between children with and without ASD in inclusive preschool settings are discussed. [ABSTRACT FROM AUTHOR]

An experimental and theoretical investigation on the chemical reactivity of fullerene cations (Cn+, n = [36, 60]) with amino acid molecules (e.g., isoleucine, C6H13NO2) is performed. The results show that, in the gas phase, fullerene cations can react with amino acid molecules to form fullerene/amino acid cluster cations with high efficiency. The formation rate constants for the ion–molecule collision reactions between fullerene cations and isoleucine are estimated under the pseudo-first-order reaction condition. We find the formation rate constants increase gradually with a declining C-atom number of fullerene cations (Cn+, n = [46, 60]), and depict a plateau in the reactivity for smaller fullerene cations (Cn+, n = [36, 44]). More importantly, by comparing to its neighbor fullerenes, the magic number of C-atom counts (54, 58) that process with enhanced chemical reactivity are determined. We also obtained the molecular structures and binding energies for the fullerene-monoisoleucine adducts by quantum chemical calculations, which give a good explanation for the magic number chemical reactivity and the enhanced chemical reactivity of smaller fullerene cations. We infer that our results demonstrate the importance of ion–molecule reactions to the formation of large and complex fullerene-amino acid derivatives in the ISM. The high reactivity of fullerene species may indicate that amino acid molecules or other related prebiotic compounds can accrete on small interstellar carbon dust grains. [ABSTRACT FROM AUTHOR]

College is a key period for students' specialty study and development, and an important stage of career exploration. We examined the relationship between proactive personality, career adaptability, and perceived social support and specialty identity among 610 Chinese college students. The mediating effect of perceived social support was greater than that of specialty identity. Therefore, providing more social support to college students may be more conducive to increasing their career adaptability. The chain intermediary effect of perceived social support indicated that specialty identity is also significant. Thus, college students with a more proactive personality can perceive more emotional support and study harder, thereby increasing their specialty identity and career adaptability. Results of this study can help guide universities in offering courses and activities that promote students' career adaptability with perceived social support and specialty identity in mind. Results also provide a model for future study of the influence of proactive personality on college student career adaptability. [ABSTRACT FROM AUTHOR]

The influences of including visual supports and strategies to increase motivation for children with autism spectrum disorder (ASD) in motor assessments were examined. 97 children with ASD and 117 age-matched typically developing (TD) children performed the Movement Assessment Battery for Children, Second Edition (MABC-2) under traditional, visual support, motivation, and visual support plus motivation protocols. Results showed that children with ASD elicited lower MABC-2 scores than TD children. Moreover, in children with ASD, the visual support protocol, but not the motivation protocol, produced higher scores on ball and balance skills than the traditional protocol. These findings indicated that children with ASD were developmentally delayed in motor skills; however, their performance may be improved by including visual supports in motor assessments. [ABSTRACT FROM AUTHOR]

Objective: To explore the risk factors for intrapartum fever and to develop a nomogram to predict the incidence of intrapartum fever.Methods: The general demographic characteristics and perinatal factors of 696 parturients who underwent vaginal birth at the Affiliated Hospital of Xuzhou Medical University from May 2019 to April 2020 were retrospectively analysed. Data was collected from May 2019 to October 2019 on 487 pregnant women who formed a training cohort. A multivariate logistic regression model was used to identify the independent risk factors associated with intrapartum fever during vaginal birth, and a nomogram was developed to predict the occurrence. To verify the nomogram, data was collected from January 2020 to April in 2020 from 209 pregnant women who formed a validation cohort.Results: The incidence of intrapartum fever in the training cohort was found in 72 of the 487 parturients (14.8%), and the incidence of intrapartum fever in the validation cohort was 31 of the 209 parturients (14.8%). Multivariate logistic regression analysis showed that the following factors were significantly related to intrapartum fever: primiparas (odds ratio [OR] 2.43; 95% confidence interval [CI] 1.15-5.15), epidural labour analgesia (OR 2.89; 95% CI 1.23-6.82), premature rupture of membranes (OR 2.37; 95% CI 1.13-4.95), second stage of labour ≥ 120 min (OR 4.36; 95% CI 1.42-13.41), amniotic fluid pollution degree III (OR 10.39; 95% CI 3.30-32.73), and foetal weight ≥ 4000 g (OR 7.49; 95% CI 2.12-26.54). Based on clinical experience and previous studies, the duration of epidural labour analgesia also appeared to be a meaningful factor for intrapartum fever; therefore, these seven variables were used to develop a nomogram to predict intrapartum fever in parturients. The nomogram achieved a good area under the ROC curve of 0.86 and 0.81 in the training and in the validation cohorts, respectively. Additionally, the nomogram had a well-fitted calibration curve, which also showed excellent diagnostic performance.Conclusion: We constructed a model to predict the occurrence of fever during childbirth and developed an accessible nomogram to help doctors assess the risk of fever during childbirth. Such assessment may be helpful in implementing reasonable treatment measures.Trial Registration: Clinical Trial Registration: ( www.chictr.org.cn ChiCTR2000035593 ). [ABSTRACT FROM AUTHOR]

Ensuring running stability and minimising wheel tread wear are critical factors for enhancing the dynamic performance of high-speed trains. As an efficient method for improving vehicle performances, previous studies on suspension parameter optimisation have not fully considered these two factors. It is essential to pay attention to stability at extreme wheel-rail contact states, and the wheel wear evolution needs to be revealed instead of investigating the wear performance only through an index like wear number. This research aims to investigate the stability/wear Pareto optimisation of bogie suspension parameters for a high-speed passenger train. Stability-related indices are defined as the lateral ride comfort index at low equivalent conicity and the bogie frame acceleration at high conicity. To represent the long-term wheel wear performance, a contact spreading index is proposed and combined with the wear number index. The key suspension parameters are optimised through the genetic algorithm NSGA-II. The obtained Pareto front clearly reveals the relationship between the objective functions. To meet different performance requirements, four distinct matching rules of the suspension parameters are summarised by employing clustering analysis. Finally, the applicability of the parameter matching rules is examined by analysing stability at different equivalent conicities and wheel wear evolution. [ABSTRACT FROM AUTHOR]

Poly(D,L-lactide) (PDLLA) polymer is widely used in biomedical applications. To control the degradation of PDLLA, as well as to ensure effective quality control of the polymer raw material, it is essential to have analytical methods capable of analyzing the PDLLA oligomer species content quantitatively. In this study, liquid chromatography-mass spectrometry (LC-MS) based analytical methods were developed to quantitate oligomer species from dimer to 15mer (total of 14 analytes) in the PDLLA polymer resin. Negative electrospray ionization was employed as the LC-MS interface. For the lactic acid dimer and trimer analysis, a SIELC Primesep SB column was used for high performance liquid chromatography (HPLC) separation and selected reaction monitoring (SRM) was used as the acquisition mode. For other lactic acid oligomer (4mer to 15mer) analysis, a Phenomenex Synergi™ 4 µm Polar-RP column was used, and selected ion monitoring (SIM) was used as the acquisition mode. Both columns demonstrated good tolerability for samples with high polymer content which is critical for method development. Analytical parameters such as calibration, correlation, accuracy, and precision were evaluated. Quadratic functions best described the correlation between response and concentration for each oligomer analyte. Excellent accuracy and precision were demonstrated with both methods. The methods developed in this study can be used to evaluate the impact of manufacturing process on polymers and can also be a good reference for oligomer analysis method development of similar polymers. [ABSTRACT FROM AUTHOR]

Rapid identification and quantification of pork and duck meat adulterated in ground beef were successfully performed by 1H NMR spectra combined with chemometrics. In principal component analysis (PCA), beef had a higher content of methionine and glutamine, which may be the key to distinguishing beef from pork and duck. Both of the binary and ternary adulterated beef could be successfully discriminated by orthogonal partial least squares discriminant analysis (OPLS-DA), with a discrimination accuracy of 100%. Leucine, isoleucine, methionine and glutamine were screened out as the potential markers for beef adulteration. After verification by external samples, the partial least squares (PLS) model was proved to be accurate in predicting binary and ternary adulteration levels in beef, with the determination coefficients R2p of 0.9153 and 0.9348, respectively, and the root mean square error (RMSEP) of 0.1112 and 0.0821, respectively. These results provide a comprehensive perspective on beef adulteration and improve understanding of the relationship between metabolites and meat. • 1H NMR combined with Chemometrics to detect adulteration of beef rapidly. • Potential markers were screened out in beef adulteration. • Not only suitable for the binary adulteration system, but also the ternary system. • This method is faster and easier than traditional methods. [ABSTRACT FROM AUTHOR]

Food-intestine interaction study has always been a hot topic in food science and nutrition due to diverse physiological functions of intestine. Compared to expensive animal models with limited screening capabilities, the simple, reliable and highly reproducible intestinal cell models are widely used in food-intestine interaction study. There are many functional cell models used to simulate the intestine in vitro , among which the Caco-2 cell model is one of the most widely used and classical models. Recently years, the differentiated Caco-2 cell model has been greatly developed due to the development of various technologies, which not only overcomes the limitations of the traditional model, but also further broadens its application. This review aims to overview the current applications of the differentiated Caco-2 cell model as a specialized model of intestinal cells in vitro , as well as new approaches solving the existing challenges of utilization, which can guide its future trends in interaction between food factors and the intestine. Key findings and conclusions : With high flexibility, high repeatability and low cost, the differentiated Caco-2 cell model has been applied to a variety of intestinal studies including intestinal absorption, intestinal transport, intestinal metabolism, intestinal barrier, intestinal immunity and intestinal adhesion. Furthermore, future study should break limitations of traditional models with the help of automation, biochemistry, molecular biology and cells co-culture, so as to make it more closer to the internal environment without sacrificing its simplicity and reliability, and more suitable for cost-effective large-scale analysis of food-intestine interaction. • Caco-2 monolayer express some structural and functional characteristics of intestine. • Caco-2 cell models applied to nutrition absorption, transport and metabolism in gut. • Effects of food factors on intestinal functions were study using Caco-2 cell models. • Molecular biology and automation are future trends to optimize Caco-2 cell models. [ABSTRACT FROM AUTHOR]

The purpose of the present study was to evaluate the effectiveness of a video modeling (VM) procedure at teaching three staff members who were working with children with autism spectrum disorder (ASD) to implement a token economy, use an error correction procedure, and conduct a multiple stimulus without replacement preference assessment. The study was conducted at a summer camp for children with ASD located on a university campus and at a school for students with special needs in mainland China. All participants successfully generalized instructional skills learned during the VM intervention to sessions with children with ASD. Maintenance of instructional skills was also seen during follow‐up. These results indicate VM to be an economical and effective approach to training staff to implement various behavioral strategies. Moreover, the validity of VM as an effective intervention for staff training is increased by inclusion of blind ratings by five Board Certified Behavior Analysts. [ABSTRACT FROM AUTHOR]

To examine the evolution processes of the nitrogen-containing polycyclic aromatic hydrocarbon (PAH) molecules occurring in interstellar environments, in this work we focus on the formation of large covalently bonded N-substituted polyaromatic species and their photochemistry behaviour in the gas phase. The experimental results show large PANH (e.g. DC/acridine and DC/phenazine) cluster cations formed in a chemical reaction between large PAH (e.g. dicoronylene, DC, C48H20) cations and small PANHs (e.g. acridine, C13H9N, or phenazine, C12H8N2) by gas-phase condensation through ion–molecule reactions. With laser irradiation, PANH cluster cations are involved in a complex photofragmentation process (e.g. dehydrogenation, HCN/CN, C2 or N2 units lost) and then form large PANH/PAH or multiple dehydrogenated molecules; in particular, the dehydrogenation of PANH clusters provides a possible way to synthesize large nitrogen-containing graphene species (e.g. C59N+ and C61N+). Also, we perform quantum-theoretical calculations on the formation and photochemistry of DC/acridine and DC/phenazine cluster cations: two types of molecular cluster are considered (C–C and C–N bond type) and the formation pathway and dissociation energy for each isomer are determined. The experimental and theoretical findings obtained give a general molecular growth pathway toward all-benzenoid aromatic species with size (> 60 C atoms) in the astrophysically relevant range, during a ground-up formation process, and offer understanding of the nitrogen element effect on their chemical-evolutionary behaviour. Also, studies of DC/acridine and DC/phenazine clusters (89–112 atoms, ∼2 nm in size) offer a feasible means of explanation for the formation of nanoscale dust grains (nitrogen element included) in space. [ABSTRACT FROM AUTHOR]

The purpose of the present study was to evaluate the effects of cognitive behavior therapy incorporated with multiple exemplar instruction on the acquisition and maintenance of five emotional skills by children with autism spectrum disorder (ASD). The experimental design was multiple-probe across five behaviors: emotion recognition, emotion recognition in context, emotion expression, seeking help, and emotion regulation. The study was conducted in a general education elementary school in China with three Chinese children (2 girls and 1 boy, aged 7–8 years) serving as participants. Results indicated that the instruction effectively increased correct responses to all five emotional skills for all three children. The acquired skills were maintained at a high level for 2 months following the completion of instruction but some skills later decreased to a slightly lower level. [ABSTRACT FROM AUTHOR]

This paper compared the effectiveness and efficiency of using computer-assisted instruction (CAI) and teacher-implemented instruction (TII) to teach visual matching skills to students with autism spectrum disorder and/or other developmental disabilities. Four school-aged students participated in this study with an alternating treatment design. The CAI incorporated discrete trial instruction with the gesture-tracking application, while the TII involved traditional one-to-one instruction using flashcards. The results indicated that all students acquired the target matching skills with generalization to similar untaught skills and maintained acquired skills at a high level for up to 5 weeks under both CAI and TII. Both CAI and TII were effective. However, CAI was more efficient than TII in regards to the prompts provided and the duration of instructional sessions. CAI also resulted in more student engagement in independent learning. [ABSTRACT FROM AUTHOR]

Objectives: Parenting children with autism spectrum disorder may be different from parenting typically developing children. The current study systematically compared mindful parenting and parenting practices in families of children with autism spectrum disorder and in families of typically developing children in China. Methods: 167 biological parents (Mage = 37.87) of Chinese children with autism spectrum disorder and 167 biological parents (Mage = 38.04) of typical developing children completed questionnaires regarding mindful parenting and parenting practices. A multivariate analysis of variance was conducted to compare between the two types of families with parent/child gender effects on mindful parenting and parenting practices. Then a series of path analyses were also conducted to examine the associations between mindful parenting and parenting practices in the two types of families. Results: Compared to parents of typically developing children, parents of children with autism spectrum disorder showed less listening with full attention, less proactive parenting, less supportiveness, more lax control, and more physical control to their children; in families of children with autism spectrum disorder (but not in families of typically developing children), fathers showed less proactive parenting and supportiveness to their children than mothers. We also found that parents' listening with full attention and awareness of children's emotions were significantly related to both positive and negative parenting practices in families of children with autism spectrum disorder. Conclusions: Chinese parents of children with autism spectrum disorder and parents of typically developing children display different parenting behaviors. These findings can provide us more future directions in studying parenting behaviors in Chinese families of children with autism spectrum disorder. [ABSTRACT FROM AUTHOR]

The purpose of this study was to evaluate the effects of intraverbal prompts on response diversity and novelty in intraverbals posed to children with autism spectrum disorder (ASD). The intraverbal prompts involving function, feature, and class (FFC) of an item were used in the training of three questions requiring multiple responses. Two Chinese boys with ASD (aged 5–6 years) served as participants. A multiple-probe across three behaviors design was employed. The results indicated that the intraverbal prompts effectively increased the number of divergent responses to all three questions. Novel responses emerged at a low level while generalization to similar questions was not observed following the training. [ABSTRACT FROM AUTHOR]

Little is known regarding the dynamic interactions between fathers and mothers in families of children with autism spectrum disorder (ASD) during the parenting process. This study used an actor–partner interdependence mediation (APIMeM) model to investigate the intrapersonal and interpersonal effects of emotion dysregulation and parenting stress on parenting behaviors among 211 pairs (total N = 422) of Chinese parents of children with ASD. The results indicated that for both fathers and mothers, there were significant indirect actor effects of parental emotion dysregulation on parents' own parenting behaviors through their own parenting stress. However, no significant direct or indirect partner effect was found in the analyses. These findings suggest that the emotional parenting dynamics occurred on the individual rather than the dyadic level in these families. [ABSTRACT FROM AUTHOR]

During its first two lunar day measurements, the visible and near‐infrared spectrometer on board the Yutu‐2 Rover of the Chang'E‐4 mission acquired six in situ reflectance spectra from the floor of Von Kármán crater within the South Pole‐Aitken basin. A spectral lookup table search has shown that the regolith at the landing site contains 56–72% plagioclase, 9–28% orthopyroxene, 4–19% clinopyroxene, and 2–12% olivine, in relative abundance, in agreement with the results from Kaguya Multiband Imager mineral mapping. A mineral composition analysis using measurements made by the Moon Mineralogy Mapper and the Multiband Imager has shown that the surface materials of the landing site may have been ejected from the nearby Finsen crater. This result is also supported by principal component analysis which shows a strong correlation between the compositions of the landing area and Finsen crater. Plain Language Summary: With its successful soft landing in South Pole‐Aitken basin on the lunar far side, the Chang'E‐4 mission measured six reflectance spectra during the first two lunar days. With these measurements, we obtained the mineral compositions of the landing site and identified the possible source location of regolith materials at the landing site, which may help us to uncover the mysteries of the formation of the South Pole‐Aitken basin. Key Points: We report the in situ visible‐near‐infrared reflectance spectra measured by Chang'E‐4 during the first two lunar daysWe obtained the relative mineral abundances at the landing site by using a spectral lookup tableThe surface materials of the Chang'E‐4 landing site are plagioclase rich and may have come from the nearby Finsen crater [ABSTRACT FROM AUTHOR]

In order to study the wheel polygon wear problems in high-speed trains, an iterative model of wheel wear was established based on $ 1) $ 1) the train-track rigid-flexible coupling dynamics model, $ 2) $ 2) Kik-Piotrowiski + Fastsim wheel-rail contact model, and $ 3) $ 3) Archard wear model to predict the developing process of wheel polygon. Taking a certain type of high-speed train in China as an example, the developing process of the 20-order wheel polygon is simulated. Compared with the Hertz model, the results of the Kik-Piotrowiski model are more consistent with the actual situation, and the prediction of the wheel polygon is more accurate. The results show that with the increase of vehicle running speed, the dominant order of the final wheel polygon decreases gradually, while the excitation frequency always locates between 550 and 600 Hz, which verifies the 'frequency fixed' mechanism. By comparing the development of wheel polygon wear results under three working conditions $ 1) $ 1) flexible wheelset + flexible rail, $ 2) $ 2) rigid wheelset + flexible rail, and $ 3) $ 3) flexible wheelset + rigid rail), and by analysing the harmonic response of rail, it is concluded that the third-order bending modal vibration of rail plays an important role in the forming of wheel polygon.. [ABSTRACT FROM AUTHOR]

Abstract A green physical route for producing novel multifunctional polyvinyl alcohol/kappa-carrageenan alkaline gel polymer electrolyte is developed, which is based on double-network physical cross-linked hydrogel. The alkaline gel polymer electrolyte has excellent tensile stress (2.22 MPa), stretchability (12.43 mm/mm) and ionic conductivity (0.21 S/cm). In this study, KOH is served as not only ionic donator but also cross-linking agent. A supercapacitor is assembled from polyvinyl alcohol/kappa-carrageenan alkaline gel polymer electrolyte and activated carbon electrodes, which exhibits ideal electrochemistry behavior. The electrode specific capacitance is 470 F/g at 0.5 A/g, and retains above 95% after 2000 charge/discharge cycles. Additionally, the electrochemical performance of supercapacitor under different tensile deformations (≤200%), bending angles (0–230°) and temperatures (≥-40 °C) displays a slightly reduction, indicating that the supercapacitor possesses good flexibility and low temperature resistance. These findings are desirable for applications in supercapacitor devices of flexibility or low working temperature. Graphical abstract Image 1 Highlights • KOH playing two roles of ionic donator and cross-linking agent in the AGPE. • Outstanding tensile property and ionic conductivity of PVA/carrageenan AGPE. • Superior properties of supercapacitor under deformation and low temperature. [ABSTRACT FROM AUTHOR]

Abstract Objective The Mini Sarcopenia Risk Assessment (MSRA), a new sarcopenia screening tool, has 2 versions: MSRA-7 (full version, 7 items) and MSRA-5 (short version, 5 items). We aimed to compare the diagnostic values of MSRA-7 and MSRA-5 to SARC-F for screening sarcopenia. Design A diagnostic accuracy study. Setting A community in Chengdu, China. Participants Older adults. Measurements Muscle mass, strength, and physical performance were tested using a bioimpedance analysis (BIA) device, handgrip strength, and walking speed, respectively. Using the Asian Working Group for Sarcopenia (AWGS) criteria as the gold standard, the sensitivity/specificity analyses of the 3 scales were assessed. Receiver operating characteristic (ROC) curves and area under the ROC curves (AUC) were used to compare the overall diagnostic accuracy of the 3 scales. Results We recruited 384 participants. Against the AWGS criteria, SARC-F had a sensitivity of 29.5% and a specificity of 98.1%, and the MSRA-7 had a sensitivity of 86.9% and a specificity of 39.6%, whereas the MSRA-5 had a sensitivity of 90.2% and a specificity of 70.6%. The AUCs of SARC-F, MSRA-7, and MSRA-5 were 0.89 [95% confidence interval (CI), 0.86-0.92], 0.70 (95% CI, 0.65-0.74), and 0.85 (95% CI, 0.81-0.89), respectively. The differences in AUCs between SARC-F and MSRA-7 and in those between MSRA-7 and MSRA-5 were statistically significant (P <.001), but the difference between SARC-F and MSRA-5 was not statistically significant (P =.130). Conclusion MSRA-5 may serve as a novel screening tool for sarcopenia in Chinese community-dwelling older adults. SARC-F, a class screening tool, is also suitable for this population. MSRA-5 and SARC-F demonstrated a similar diagnostic accuracy in our study population. MSRA-5 has better sensitivity, whereas SARC-F has better specificity. However, the diagnostic value of MSRA needs to be further validated in different populations. [ABSTRACT FROM AUTHOR]

This study provides new insights regarding the associations and risk factors of nine specific adverse childhood experiences (ACEs) and young children (0–5 years of age) with disabilities. Utilizing the 2016 National Survey of Children’s Health (NSCH) dataset (N = 14,494), we conducted descriptive analysis and regressions with complex survey weighting procedure. The results suggested that one in three children (35.0%) with disabilities would have at least one ACE. The prevalence rates of experiencing the nine specific ACEs were much higher for children with disabilities. Importantly, the five most prevalent ACEs for children with disabilities were hard to cover basic food and housing (40.9%), parental divorce (24.3%), alcohol/drug problems (11.1%), parent or guardian incarceration (10.6%), and adult abuse (6.8%), which were all related to family challenges. We identified several key child/family risk factors (e.g., child age, marital status, adult health) that helped inform cross-system screening, referral, and collaboration opportunities. A discussion about policy implication and further research directions is provided. [ABSTRACT FROM AUTHOR]

Since the Declaration of Salamanca in 1994, many countries, including China, have been moving toward a more inclusive approach to schooling. This column discusses the history, status quo, and future directions of Chinese inclusive education. It also examines facilitators, barriers, and challenges in the development and implementation of Chinese inclusive education and provides corresponding recommendations. [ABSTRACT FROM AUTHOR]

Objectives A nanoparticle-doped adhesive that can be controlled with magnetic forces was recently developed to deliver drugs to the pulp and improve adhesive penetration into dentin. However, it did not have bactericidal and remineralization abilities. The objectives of this study were to: (1) develop a magnetic nanoparticle-containing adhesive with dimethylaminohexadecyl methacrylate (DMAHDM), amorphous calcium phosphate nanoparticles (NACP) and magnetic nanoparticles (MNP); and (2) investigate the effects on dentin bond strength, calcium (Ca) and phosphate (P) ion release and anti-biofilm properties. Methods MNP, DMAHDM and NACP were mixed into Scotchbond SBMP at 2%, 5% and 20% by mass, respectively. Two types of magnetic nanoparticles were used: acrylate-functionalized iron nanoparticles (AINPs); and iron oxide nanoparticles (IONPs). Each type was added into the resin at 1% by mass. Dentin bonding was performed with a magnetic force application for 3 min, provided by a commercial cube-shaped magnet. Dentin shear bond strengths were measured. Streptococcus mutans biofilms were grown on resins, and metabolic activity, lactic acid and colony-forming units (CFU) were determined. Ca and P ion concentrations in, and pH of biofilm culture medium were measured. Results Magnetic nanoparticle-containing adhesive using magnetic force increased the dentin shear bond strength by 59% over SBMP Control ( p < 0.05). Adding DMAHDM and NACP did not adversely affect the dentin bond strength ( p > 0.05). The adhesive with MNP + DMAHDM + NACP reduced the S. mutans biofilm CFU by 4 logs. For the adhesive with NACP, the biofilm medium became a Ca and P ion reservoir. The biofilm culture medium of the magnetic nanoparticle-containing adhesive with NACP had a safe pH of 6.9, while the biofilm medium of commercial adhesive had a cariogenic pH of 4.5. Significance Magnetic nanoparticle-containing adhesive with DMAHDM and NACP under a magnetic force yielded much greater dentin bond strength than commercial control. The novel adhesive reduced biofilm CFU by 4 logs and increased the biofilm pH from a cariogenic pH 4.5–6.9, and therefore is promising to enhance the resin–tooth bond, strengthen tooth structures, and suppress secondary caries at the restoration margins. [ABSTRACT FROM AUTHOR]

Abstract: Efficient bifunctional oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) catalysts are of great importance for rechargeable metal–air batteries. Herein, FeNx/C catalysts are synthesized by pyrolysis of thiourea and agarose containing α‐Fe2O3 nanoplate as Fe precursor, where α‐Fe2O3 nanoplate can prevent the aggregation of carbon sheets to effectively improve the specific surface area during the carbonization process. The FeNx/C‐700‐20 catalyst displays excellent catalytic performance for both ORR and OER activity in alkaline conditions with more positive onset potential (1.1 V vs the reversible hydrogen electrode) and half‐wave potential, higher stability, and stronger methanol tolerance in alkaline solution, which are all superior to that of the commercial Pt/C catalyst. In this study, the detailed analyses demonstrate that the coexistence of Fe‐based species and high content of Fe‐Nx both play an important role for the catalytic activity. Furthermore, FeNx/C‐700‐20 as cathode catalyst in Zn–air battery possesses higher charge–discharge stability and power density compared with that of commercial Pt/C catalyst, displaying great potential in practical implementation of for the rechargeable energy devices. [ABSTRACT FROM AUTHOR]

Objectives To investigate the prevalence and associated factors of sarcopenia defined by different criteria in nursing home residents. Design A cross-sectional study. Setting Four nursing homes in Chengdu, China. Participants Elderly adults aged 65 years or older. Measurements We applied 4 diagnostic criteria [European Working Group on Sarcopenia in Older People (EWGSOP), Asia Working Group for Sarcopenia (AWGS), International Working Group on Sarcopenia (IWGS), and Foundation for the National Institutes of Health (FNIH)] to define sarcopenia. Muscle mass, strength, and function were measured based on bioimpedance analysis, handgrip strength, and walking speed, respectively. Nutrition status, activities of daily living, calf circumference (CC), and other covariates were evaluated. Results We included 277 participants. The prevalence of sarcopenia was 32.5%, 34.3%, 38.3%, and 31.4% according to the EWGSOP, AWGS, IWGS, and FNIH criteria, respectively. Fifty-eight participants (20.9%) were sarcopenic by all the 4 criteria. Regardless of the diagnostic criteria of sarcopenia, malnutrition was independently associated with sarcopenia [EWGSOP: odds ratio (OR) 4.02, 95% confidence interval (CI) 1.05-15.39; IWGS: OR 2.46, 95% CI 1.23-4.90; AWGS: OR 3.29, 95% CI 1.49-7.28; FNIH: OR 4.52, 95% CI 1.28-16.00], whereas CC was negatively associated with sarcopenia [EWGSOP: OR per standard deviation (SD) 0.32, 95% CI 0.20-0.52; IWGS: OR per SD 0.26, 95% CI 0.15-0.43; AWGS: OR per SD 0.32, 95% CI 0.19-0.52; FNIH: OR per SD 0.39, 95% CI 0.25-0.60]. Furthermore, falls ≥1 time in the past year were associated with AWGS-defined sarcopenia (OR 2.92, 95% CI 1.04-8.22). Conclusion/Implications Sarcopenia is highly prevalent in elderly Chinese nursing home residents regardless of the diagnostic criteria. Malnutrition and CC are associated with sarcopenia defined by different criteria. Therefore, it is important to assess sarcopenia and malnutrition in the management of nursing home residents. Prospective studies addressing the outcomes of sarcopenia in nursing home residents are warranted. [ABSTRACT FROM AUTHOR]

Abstract: Studies have shown that miR‐4317 is dysregulated in tumor, but the biologic role of miR‐4317 in tumor development and progression remains unknown. The present study aimed to investigate the role of miR‐4317 in human gastric cancer. Quantitative real‐time PCR was used to quantify miR‐4317 expression levels in clinical gastric cancer specimens and cell lines. MTT, colony formation and cell cycle assays were performed to identify the contributions of miR‐4317 to cell proliferation in gastric cancer cell lines. The results showed that miR‐4317 was significantly decreased in 17 clinical gastric cancer specimens compared with adjacent non‐tumor stomach tissues. Forced expression of miR‐4317 suppressed gastric cancer cell proliferation and blocked S‐G2/M transition. Bioinformatics and dual‐luciferase reporter assays confirmed that ZNF322 is a direct target of miR‐4317. Silencing ZNF322 recapitulated the cellular and molecular effects seen upon miR‐4317 overexpression. These findings indicate that miR‐4317 represses the proliferation of gastric cancer cell, at least in part, by targeting and suppressing ZNF322 and that it may serve as a therapeutic target for gastric cancer treatment. [ABSTRACT FROM AUTHOR]

[Display omitted] • A gel electrolyte with asymmetric structure was prepared. • The gel electrolyte possesses thermal stability and flame retardant. • The gel electrolyte utilizes an electro-spun network as structural scaffolds. • The SiO 2 -polyvinyl alcohol was loaded at one surface of an electro-spun network. • The gel electrolyte simultaneously solves problems of the S cathode and Li anode. A main huddle against the practical application of lithium-sulfur battery lies in serious safety concerns due to liquid organic electrolyte, shuttling of polysulfides and formation of lithium dendrites. Herein, we have devised an asymmetric and structurally stable gel electrolyte system to enable high ionic conductivity, flame-retardancy, and effective blockage of shuttling. Such a multi-functional gel electrolyte utilizes an electro-spun network of interwoven nano-fibers of poly vinylidene fluoride-co-hexafluoropropylene (PVDF-HFP) as structural scaffolds, with SiO 2 -polyvinyl alcohol (SiO 2 @PVA) suspension being loaded at one surface by blade coating. Such asymmetrically coated PVDF-HFP membranes are highly wettable that is essential to thorough gelling, with its well-connected porous channels to enable outstanding ionic conductivity above the limit by conventional Celgard separator, to accommodate huge volumetric changes over redox reactions, to shield polysulfides and fend off lithium dendrites. Ultimately, application of the gel electrolyte to a model Li-S cell with cathode containing 90% S delivered high initial capacity of 1439 mA h g−1 at 0.1C and a remarkable cycling stability over 300 cycles at 1C. The current gel electrolyte is expected to provide a valuable means for developing safe low-cost and durable Li–S batteries of practical importance. [ABSTRACT FROM AUTHOR]

Given the impact of the global COVID-19 pandemic on children's schooling and learning, evidence for interventions implemented by parents is urgently needed. This study aimed to evaluate the effects of a parent-mediated LEGO intervention on the social interactions of four children on the autism spectrum in China. The intervention involved four sets of two parents engaging with their child in collaborative LEGO construction, with each person assigned a role as Engineer, Supplier, or Builder. Using a multiple probe design across the four family triads, the intervention effectively increased spontaneous social initiations and responses in all four children, and these behaviors were maintained for 6 weeks following the intervention. The effect on inappropriate interactions was not detected; parental prompts increased in initial intervention sessions but decreased over time. Parents implemented the intervention at home with high fidelity. Efficacy of the intervention and potential benefits of virtual parent training are discussed. [ABSTRACT FROM AUTHOR]

The purpose of this study was to examine the effects of a peer-mediated LEGO® play intervention on improving social skills for children with ASD in an inclusive preschool in China. Three boys with ASD and 13 typically developing children participated in this study. A multiple-probe across participants design was used. The intervention consisted of LEGO® construction activities incorporated with peer-mediated strategies for one child with ASD and two typically developing peers. The intervention sessions were conducted two sessions per week with a total of 28-31 sessions for each participant. Results indicated that all three children with ASD increased their social initiations and responses following the completion of the intervention. Social validity was also obtained. [ABSTRACT FROM AUTHOR]

Much effort has been made to develop the semiconductor photocatalysis, but it is still challenging to fabricate low-cost and high-activity photocatalysts. In this study, Hematite (α-Fe 2 O 3 ) with three kinds of morphologies including dodecahedron, tetrakaidecahedron and hexagonal nanoplates have been synthesized without any organic reagents. The photocatalytic performance reveals that the dodecahedron with exposed {1 0 1} facets is superior to the hexagonal nanoplates with predominant exposure of {0 0 1} facets in the case of similar BET surface area. For further enhancement of photocatalytic activity, carbon layer was coated on dodecahedral α-Fe 2 O 3 through the self-polymerization of dopamine and following pyrolysis at 400 °C under Ar flow. Compared with the pristine dodecahedral α-Fe 2 O 3 , the α-Fe 2 O 3 /C composites exhibit stronger visible absorption, lower photoexcited electron-hole pairs recombination rate and better photodegradation activity. The photocatalytic performance showed the degradation rate of α-Fe 2 O 3 -D/4.5C is nearly 6 times higher than pristine α-Fe 2 O 3 , which have great potential for photocatalysis applications. [ABSTRACT FROM AUTHOR]

Microfluidic microbial fuel cell is considered as a new development direction of green and sustainable energy systems. Compared with other microbial electrochemical reactors, microfluidic microbial fuel cells have lower cost and higher energy efficiency. In practice, vibration is a non-negligible factor affecting the performance of microfluidic microbial fuel cell. However, numerical studies in this area are lacking. In the current work, a two-dimensional transient model for microfluidic microbial fuel cell is established by coupling the vibration force field with hydrodynamics, mass transfer, whole-cell electrochemical reaction kinetics and microbial growth. The correctness of the model is guaranteed by comparing the experimental data with simulation results. After model validation, an integrated assessment of the vibration effect on microfluidic microbial fuel cell is obtained. Major conclusions show that vibration excitation can inhibit the growth of electricigens inside the anode, thus reducing the output performance of microfluidic microbial fuel cell. Increasing the vibration intensity and frequency will exacerbate this effect. However, appropriate vibration excitation is beneficial to the substrate removal of microfluidic microbial fuel cell. Vibration will destroy the laminar flow pattern in the microchannel and increase the bacteria concentration inside the cathode. Additionally, the increment of feed flow rate is conductive to enhancing the anti-vibration ability of the cell [Display omitted] • The transient bi-population model for microfluidic microbial fuel cell is proposed. • Uneven distributions of bacteria on both anode and cathode are revealed. • Effects of vibration force on cell performance and bacteria distribution are studied. • The anti-vibration abilities of microfluidic microbial fuel cells are evaluated. [ABSTRACT FROM AUTHOR]