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Background. Alzheimer’s disease (AD) is a common health condition affecting senile people and leads to severe cognitive dysfunctions. Acupuncture has been shown to be a possible alternative natural remedy for AD in some animal studies. Objective. To perform a systematic review to identify the effect of verum-acupuncture compared with sham-acupuncture on learning and memory performance among animal models of AD. Methods. Experimental animal studies of treating AD via verum- and sham- acupuncture were searched in nine electronic databases, including Sciverse ScienceDirect, PubMed, Springer, Ebsco Medline, AMED, EMBASE (Elsevier), Scopus (Elsevier), PsycINFO (ProQuest), and OVID from the dates of the databases’ inception to June 2019. The Morris water maze test was considered as an outcome measure. The software Revman 5.3 and Stata 16.0 were used to conduct the meta-analysis. Heterogeneity was examined by using I2 statistics. The publication bias was assessed via Begg’s test by Stata 16.0. Results. Twelve studies involving 229 animals met the inclusion criteria. Most of the studies had a moderate quality according to SYRCLE's risk of bias tool for animal studies. The results of the meta-analysis indicated that verum-acupuncture could reduce the escape latency (MD = −12.90, 95% CI (−17.08, −8.71), ) and increase the time spent in the original platform quadrant (MD = 7.28, 95% CI (4.23, 10.33), ) and frequency of the crossing former platform (MD = 2.01, 95% CI (1.53, 2.50), ) compared with the sham-acupuncture. Conclusions. Acupuncture is effective in improving cognitive functions in AD animal models, and this benefit is more than just a placebo effect. Further clinical trials are needed to confirm the findings. This work was sponsored by the Teaching and Research Award Program for Outstanding Young Teachers, Shanghai Sanda University (No. 2018zz13) and Special Project for Clinical Research, Shanghai Municipal Health Commission (No. 20174Y0009). The publication of this article was funded by the Qatar National Library. The authors would like to extend their gratitude to Yuen-Shan Ho, from School of Nursing, The Hong Kong Polytechnic University, for inspiring them to seek the underlying research directions. Besides, the authors thank Hai-Dong Guo, from School of Basic Medicine, Shanghai University of Traditional Chinese Medicine, for providing help in organizing the data and Yan Xu, the chair of Nursing Department, Shanghai Sanda University, for providing general support.

Objective This study is conducted to investigate the effects differences of escitalopram with or without combined electroacupuncture (EA) among male inpatients with a diagnosis of alcohol dependence and comorbid protracted alcohol withdrawal symptoms (PAWS). Methods A total of 62 participants who met the inclusion criteria were enrolled in a two-arm randomized, placebo controlled, patients-blind trial and allocated to an escitalopram with real-EA group (real-EA group, patients= 31) and an escitalopram with sham-EA group (sham-EA group, patients= 31), respectively. In addition to the oral administration of escitalopram for total four weeks, patients in each group received corresponding EA treatment five days per week and two days off for consecutive four weeks. Both serum homocysteine (Hcy) test and electrophysiological tests, including event-related potentials (ERPs) and exploratory eye movement (EEM) were performed at pre- and post-treatment. Additionally, the global scores of Penn Alcohol Craving Scale (PACS), 17-items Hamilton Depression Rating Scale (HAMD-17), and Hamilton Anxiety Scale (HAMA) were used for assessing the subjective emotion experience of patients, respectively. Meanwhile, adverse effects were monitored and recorded. Results After four-week treatment, the global scores of PACS and HAMD-17 declined significantly in both groups (both P 0.05). According to the parameters of ERPs, significant declines for N2PL, P3PL, and P3amp were observed in both two groups (all P Conclusion (1) Escitalopram with EA may be a potential alternative therapy for mitigating PAWS among male inpatients with alcohol dependence. (2) Escitalopram with EA might improve the alcohol-dependence induced cognitive dysfunctions via upregulating the expression of Hcy.

Objective This study is conducted to determine effects of manual acupuncture (MA) in patients with a diagnosis of major depressive disorder (MDD) and comorbid insomnia. Methods A total of 67 participants who met the inclusion criteria were randomly enrolled in a two-arm randomized, placebo controlled, patients-blind trial and allocated to a real-MA group (patients = 34) and a sham-MA group (patients = 33). Patients in the real-MA group were treated on ‘Five-shen acupoints’, including Sishencōng (四神聪 EX-HN 1), Shenting (神庭 GV 24), Shendao (神道 GV 11), bilateral Běnshen (本神 GB 13), and bilateral Shenmen (神门 HT 7). Though being punctured on the same acupoints, patients in the sham-MA group were treated by a placebo acupuncture approach (Streitberger Placebo-needle). Each group received corresponding interventions every other day, three times a week for total eight weeks. Both polysomnography (PSG) and testing of serum biological markers such as neuropeptide Y (NPY) and substance P (SP) were performed at pre- and post-treatment. Additionally, the global scores of Pittsburgh sleep quality index (PSQI) and the global scores of 17-items Hamilton Depression Rating Scale (HAMD17) were used for assessing the subjective sleep and emotion experience of patients, respectively. Meanwhile, adverse effects were monitored and recorded. Results After eight-week treatment, the global scores of PSQI and global scores of HAMD17 declined significantly (both P 0.05). According to the parameters of PSG, striking decline were observed in sleep latency (SL) and wake after sleep onset (WASO) and striking climb were observed in total sleep time (TST) and sleep efficiency (SE) in the real-MA group after treatment (P 0.05, respectively). Additionally, there were no significant differences in awakening times (ATs) and rapid eyes movement sleep latency (REM-SL) in both two groups after treatment (both P > 0.05). Meanwhile, the expression of NPY increased significantly and the expression of SP decreased significantly in the real-MA group after interventions (both P 0.05). No serious adverse event was reported in either real- or sham- MA group. Conclusion (1) MA may be a potential alternative therapy for improving MDD and comorbid insomnia (particularly in extending total sleep time and shortening wake-up duration and sleep latency) via upregulating the expression of NPY and downregulating the expression of SP; more importantly, this efficacy of acupuncture can not be replaced by sham-acupuncture acting on the same acupoints with the same treatment frequency. (2) There is insufficient evidence to prove that MA can effectively reduce the number of arousals.

Objective This study is conducted to determine the effects of SOOJI CHIM (Koryo hand acupuncture, KHA) therapy on sleep structures and perimenopause symptoms among insomniacs. Methods Totally 49 participants who met the inclusion criteria were enrolled in a two-arm randomized, placebo controlled, patients-blind trial, with 24 cases allocated to a real-KHA group and 25 cases allocated to a sham-KHA group. Patients in each group received corresponding treatment every other day, three times a week for total eight weeks. Both actigraphy and testing of serum hormones level reflected by biological markers such as follicle-stimulating hormone (FSH), luteinizing hormone (LH) and estradiol (E2) were performed at pre- and post-treatment. Additionally, the scores of Pittsburgh sleep quality index (PSQI) was used for assessing the subjective sleep experience of insomniacs. Meanwhile, adverse effects were monitored and recorded. Results After eight-week treatment, the global scores of PSQI declined significantly (P 0.05). According to the outcomes of actigraphy, a striking increase was observed in both sleep efficiency (SE) and total sleep time (TST) in the real-KHA group (both P 0.05). However, no significant changes of sleep awakenings (SA) in both groups was found after treatment (both P>0.05). Meanwhile, FSH and LH in the real-KHA group decreased markedly after intervention (both P 0.05). The fluctuation of E2 levels were not significant in both groups (both P>0.05). No serious adverse event was reported in either real- or sham- KHA group. Conclusion KHA may be a potential alternative therapy for improving perimenopausal insomnia via down regulating the levels of FSH and LH.

This paper examined the method to evaluate structural complexity of circular economy system’s industrial chain, which applied entropy information and hierarchical metrics to produce complexity degrees according to the theory of complex system. We developed an evaluation model to make a general metrics for circular economy system of industrial chains. The development of the evaluation tree drew upon five factors to identify the structural complexity. The evaluation model generated unitive entropy information from six data definition (node, level of community, metabolic span, degree of node, number of relation and connectivity of node) according to the evaluation tree. The industrial chains of Tashan circular economy park of Datong Coal Mine Group and Gujiao circular economy park of Xishan Coal-Electricity Group were evaluated by the proposed method. The key factors stunted by the decline of structural complexity were identified and the unitive metrics of entropy information of the industrial chain was shown for realigning the circular economy systems.

For studying the circular mechanism and the operating mode of modern mine, this paper reviewed the current development situations of circular economy modes and some typical circular economy parks in coal mining industry at home and abroad. With the Xishan coal mine areas as the investigated objective, which operated by Xishan Coal-electricity Group in Shanxi Province of China, the characterized circular economy mode is put forwarded and concluded as “33386” development mode. Furthermore, the structure and industrial chains of Xishan circular economy system are researched in whole and interpreted in part. This is a successful attempt on the coal mining industry with a new development mode and a complete circulation of resourses in practice.

Analyzed the situations and characteristics of thin coal seam mining and its mining technologies, and introduced the mining innovation technology used by Tianchen Coal Mine of Zhaozhuang Coal Company of China. This innovation technology combined the fully mechanized mining with individual props, and the working face of mining is over length, irregular form and double units. The rotational adjusting mining technology on thin coal seam is also practiced in this new mining technology. The detail technologies, such as outlays of working face and ways, mining methods, equipments of cutting, transporting and sporting, have been introduced. So that, using the synthetic and creative mining technologies, Tianchen Coal Mine solves the mining problems of thin coal seam successfully.

When 85 cervical type spondylosis patients randomly lay on one's back and on one's right side the 8 different tresles and pillows. We survey indexes of the cervical spine anatomy, for example cervical arcs and angles of cervical spine and level line. We appraise relation of balance between different trestle or pillow and cervical spine. liquid needle-free injection, jet power, stagnation pressure

Shenfu Dongsheng Coal Co. Ltd (abbreviation for Shendong Company) is a large state-owned enterprise mainly engaging in coal production. After 20 years of hard work, the company had experienced soaring development and has earned itself eight world records in the mining industry. In this process of development and achievement, automatic controlling and mechanization had played very important roles. Combined with a refined management mechanism, the automatic equipment and other technologies have created remarkable productivity. Focusing upon the Daliuta Drift Mine, a typical modernized mine, as a case study, this paper introduces the systems of automatic control instigated by Shendong Company. In turn, these are reviewed as to their use and effectiveness. This is very typical case study of informational and cybernetic application in practice.