167 results on '"Huang, Danny T."'
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2. Hepatic glutamine synthetase controls N5-methylglutamine in homeostasis and cancer
3. PTEN deficiency exposes a requirement for an ARF GTPase module for integrin‐dependent invasion in ovarian cancer
4. PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371
5. Structure of UBE2K–Ub/E3/polyUb reveals mechanisms of K48-linked Ub chain extension
6. AlphaFold Ensemble Competition Screens Enable Peptide Binder Design with Single-Residue Sensitivity.
7. An engineered ubiquitin binding coiled coil peptide.
8. DTX3L ubiquitin ligase ubiquitinates single-stranded nucleic acids
9. E3 ligase-inactivation rewires CBL interactome to elicit oncogenesis by hijacking RTK–CBL–CIN85 axis
10. PRL2 phosphatase promotes oncogenic KIT signaling in leukemia cells through modulating CBL phosphorylation
11. Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain
12. Single-Turnover RING/U-Box E3-Mediated Lysine Discharge Assays
13. Author Reply to Peer Reviews of PTEN deficiency exposes a requirement for an ARF GTPase module in integrin-dependent invasion in ovarian cancer.
14. PTEN deficiency exposes a requirement for an ARF GTPase module in integrin-dependent invasion in ovarian cancer
15. Hepatic glutamine synthetase controls N5-methylglutamine in homeostasis and cancer
16. Bivalent binding of p14ARF to MDM2 RING and acidic domains inhibits E3 ligase function
17. Corrigendum: Differential requirements for MDM2 E3 activity during embryogenesis and in adult mice
18. Thermodynamic analysis of catalysis by the dihydroorotases from hamster and Bacillus caldolyticus, as compared with the uncatalyzed reaction
19. (super 13)C and (super 15)N isotope effects for conversion of L-dihydroorotate to N-carbamyl-L-aspartate using dihydroorotase from Hamster and Bacillus caldolyticus
20. Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant
21. Ubiquitin-like protein activation
22. Differential requirements for MDM2 E3 activity during embryogenesis and in adult mice
23. Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases
24. DELTEX2 C-terminal domain recognizes and recruits ADP-ribosylated proteins for ubiquitination
25. Expression, Purification, and Characterization of the E1 for Human NEDD8, the Heterodimeric APPBP1–UBA3 Complex
26. Structural insights into non-covalent ubiquitin activation of the cIAP1-UbcH5B~ubiquitin complex
27. Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity
28. Structure specific recognition protein-1 (SSRP1) is an elongated homodimer that binds histones
29. Identification and Characterization of Mutations in Ubiquitin Required for Non-covalent Dimer Formation
30. Differential requirements for MDM2 E3 activity during embryogenesis and in adult mice
31. A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants
32. Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity
33. Casitas B-lineage lymphoma linker helix mutations found in myeloproliferative neoplasms affect conformation
34. Structural insights into the catalysis and regulation of E3 ubiquitin ligases
35. Ubiquitination Accomplished: E1 and E2 Enzymes Were Not Necessary
36. Structure of BIRC7–E2 ubiquitin conjugate reveals the mechanism of ubiquitin transfer by a RING dimer
37. Activation of a Primed RING E3-E2–Ubiquitin Complex by Non-Covalent Ubiquitin
38. Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3
39. BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer
40. Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl
41. Crystal Structure of UBA2ufd-Ubc9: Insights into E1-E2 Interactions in Sumo Pathways
42. E2-RING Expansion of the NEDD8 Cascade Confers Specificity to Cullin Modification
43. Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin within the NEDD8 E2
44. Breaking up with a kinky SUMO
45. 13C and 15N Isotope Effects for Conversion of l-Dihydroorotate to N-Carbamyl-l-aspartate Using Dihydroorotase from Hamster and Bacillus caldolyticus
46. E2 conjugating enzymes must disengage from their E1 enzymes before E3-dependent ubiquitin and ubiquitin-like transfer
47. Structural Basis for Recruitment of Ubc12 by an E2 Binding Domain in NEDD8's E1
48. A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8
49. The Structure of the APPBP1-UBA3-NEDD8-ATP Complex Reveals the Basis for Selective Ubiquitin-like Protein Activation by an E1
50. Crystallization of hamster dihydroorotase: involvement of a disulfide-linked tetrameric form
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