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Your search keyword '"Huang, Guo Xin"' showing total 15 results
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15 results on '"Huang, Guo Xin"'

2. Sirtuin 5 deficiency increases disease severity in rats with adjuvant-induced arthritis

Author

Zhang, Ni, Zhang, Hui, Law, Betty Yuen Kwan, Dias, Ivo Ricardo De Seabra Rodrigues, Qiu, Cong Ling, Zeng, Wu, Dan Pan, Hu, Chen, Jin Yun, Bai, Yan Fu, Lv, Jing, Qu, Li Qun, Chen, Xi, Huang, Qi, Zhang, Wei, Yang, Li Jun, Yu, Lu, Han, Yu, Huang, Guo Xin, Wang, Hui Miao, Sun, Xiao Lei, Zhang, Yun, He, Hu Qiang, Dan Luo, Wei, Xiao, Yao, Zhou, Jian, Xu, Ting, Huang, Qing Chun, Wu, Min, Huang, Zhi Sheng, Liu, Wei, Wong, Vincent Kam Wai, and Liu, Liang

Published
2020
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4. Huangqin decoction ameliorates DSS-induced ulcerative colitis: Role of gut microbiota and amino acid metabolism, mTOR pathway and intestinal epithelial barrier

Author

Li, Mu-xia, primary, Li, Min-yao, additional, Lei, Jun-xuan, additional, Wu, Yu-zhu, additional, Li, Ze-hao, additional, Chen, Lin-ming, additional, Zhou, Chang-lin, additional, Su, Ji-yan, additional, Huang, Guo-xin, additional, Huang, Xiao-qi, additional, and Zheng, Xue-bao, additional

Published
2022
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7. Saponins isolated from Radix polygalae extent lifespan by modulating complement C3 and gut microbiota

Author

Zeng, Wu, primary, Wu, An Guo, additional, Zhou, Xiao-Gang, additional, Khan, Imran, additional, Zhang, Rui Long, additional, Lo, Hang Hong, additional, Qu, Li Qun, additional, Song, Lin Lin, additional, Yun, Xiao Yun, additional, Wang, Hui Miao, additional, Chen, Juan, additional, Ng, Jerome P.L., additional, Ren, Fang, additional, Yuan, Si Yu, additional, Yu, Lu, additional, Tang, Yong, additional, Huang, Guo Xin, additional, Wong, Vincent Kam Wai, additional, Chung, Sookja Kim, additional, Mok, Simon Wing Fai, additional, Qin, Da Lian, additional, Sun, Hua Lin, additional, Liu, Liang, additional, Hsiao, W.L. Wendy, additional, and Law, Betty Yuen Kwan, additional

Published
2021
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8. The cross-sectional study of hospitalized coronavirus disease 2019 patients in Xiangyang, Hubei province

Author

Ai, Jin-Wei, primary, Chen, Jun-Wen, additional, Wang, Yong, additional, Liu, Xiao-Yun, additional, Fan, Wu-Feng, additional, Qu, Gao-Jing, additional, Zhang, Mei-Ling, additional, Pei, Sheng-Duo, additional, Tang, Bo-Wen, additional, Yuan, Shuai, additional, Li, Yang, additional, Wang, Li-Sha, additional, Huang, Guo-Xin, additional, and Pei, Bin, additional

Published
2020
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13. Effect of Niobium Doping on Structural Stability and Electrochemical Properties of LiNiO2Cathode for Li-Ion Batteries

Author

Huang, Guo-Xin, Wang, Ruo-Heng, Lv, Xiao-Yan, Su, Jing, Long, Yun-Fei, Qin, Zu-Zeng, and Wen, Yan-Xuan

Abstract

LiNiO2, a promising cobalt-free cathode, suffers from poor cyclic stability and inferior rate performance due to structural degradation. A strategy based on the synergistic effect of a strong Nb–O bond (753 kJ mol−1), high valence state (Nb5+), and larger ionic radius (0.64 Å) was developed to improve the properties of LiNiO2. The synergistic effects can effectively improve lattice stability, lower Li+/Ni2+cation mixing, expand LiO6-slab spaces, enhance the conductivity and inhibit the H2–H3 phase transition, which can enhance the stability of the layered structure, accelerate Li+diffusion and alleviate mechanical damage. Therefore, LiN0.99Nb0.01O2exhibits higher capacity retention (91.4% after 100 cycles at 0.5C) and superior rate capability (143 mAh g−1at 5C). As a comparison, the data of bare LiNiO2is 69.2% and 127 mAh g−1under the same conditions. These results further demonstrate the effectiveness of the proposed doping strategy.

Published
2022
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15. Effect of Heat Treatment on the Antitumor Activity of Lactoferrin in Human Colon Tumor (HT29) Model.

Author

Li HY, Yang HG, Li P, Wang YZ, Huang GX, Xing L, Wang JQ, and Zheng N

Subjects
Animals, Antineoplastic Agents chemistry, Apoptosis drug effects, Cell Movement drug effects, Cell Proliferation drug effects, Colonic Neoplasms genetics, Colonic Neoplasms metabolism, Colonic Neoplasms physiopathology, HT29 Cells, Hot Temperature, Humans, Lactoferrin chemistry, MAP Kinase Signaling System, Male, Mice, Mice, Inbred BALB C, Mice, Nude, Phosphatidylinositol 3-Kinases genetics, Phosphatidylinositol 3-Kinases metabolism, Vascular Endothelial Growth Factor A genetics, Vascular Endothelial Growth Factor A metabolism, Vascular Endothelial Growth Factor Receptor-2 genetics, Vascular Endothelial Growth Factor Receptor-2 metabolism, Xenograft Model Antitumor Assays, Antineoplastic Agents administration & dosage, Colonic Neoplasms drug therapy, Lactoferrin administration & dosage
Abstract

To investigate the effect of heat treatment on the antitumor activity of lactoferrin in colon cancer cells and colon tumors, the HT-29 (human intestinal epithelial tumor cell) cell line was exposed to lactoferrin and various heat treatments. The impacts on cell proliferation, invasion, and migration were observed in vitro, and nude mice bearing HT29 tumors were administered lactoferrin and underwent various heat treatments in vivo. In the HT29 cell proliferation test using transwell and scratch analyses, lactoferrin (20 mg/mL) without or with heat treatment (50 and 70 °C) significantly inhibited cell proliferation, migration, and invasion (compared with the control, p < 0.05), while lactoferrin with heat treatment (100 °C) did not affect these parameters. In vivo, HT29 tumor weight was significantly reduced in the lactoferrin (without heat treatment and with 50 and 70 °C treatment) groups (1.59 ± 0.20, 1.67 ± 0.25, and 2.41 ± 0.42 g, compared with the control, p < 0.05), and there was no significant difference between the control (3.73 ± 0.33 g) and the 100 °C treatment group (3.58 ± 0.29 g). Moreover, 100 °C heat treatment reduced inhibition of the VEGFR2/VEGFA/PI3K/Akt/Erk1/2 angiogenesis pathway by lactoferrin. In summary, HT29 tumors were effectively suppressed by lactoferrin via inhibition of VEGFR2/VEGFA/PI3K/Akt/Erk1/2 pathway, and heat treatment affected the antitumor activity of lactoferrin in a temperature-dependent manner.

Published
2019
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