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14 results on '"Huang, Jieqing"'

2. cis‐Linked Cyclotetraphenylenes: Synthesis, Structures and Fluorescence Properties.

Author

Zou, Bo, Li, Jian‐An, Zhai, Zhaofen, Yu, Taoxing, Liu, Haoran, Huang, Jieqing, He, Huowang, Xu, Bingjia, and Jiang, Hua‐Wei

Subjects
FLUORESCENCE, STRAIN energy, SINGLE crystals, X-ray diffraction
Abstract

cis‐Linked cyclotetraphenylene dimer [2]c‐CTPE and trimer [3]c‐CTPE were synthesized via Pt‐mediated cyclization of cis‐diboronated tetraphenylethene. The structure of [2]c‐CTPE has been confirmed by single crystal X‐ray diffraction. The strain energy of [2]c‐CTPE and [3]c‐CTPE was calculated to be 86.28 ⋅ kJ mol−1 and 9.23 kJ ⋅ mol−1, respectively. [2]c‐CTPE and [3]c‐CTPE are typical AIEgens and show mechanofluorochromic properties. The comparisons of cis‐linked cyclotetraphenylenes with gem‐linked cyclotetraphenylenes were also discussed. [ABSTRACT FROM AUTHOR]

Published
2024
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7. 2′3′-cGAMP triggers a STING- and NF-κB–dependent broad antiviral response in Drosophila

Author

Cai, Hua, primary, Holleufer, Andreas, additional, Simonsen, Bine, additional, Schneider, Juliette, additional, Lemoine, Aurélie, additional, Gad, Hans Henrik, additional, Huang, Jingxian, additional, Huang, Jieqing, additional, Chen, Di, additional, Peng, Tao, additional, Marques, João T., additional, Hartmann, Rune, additional, Martins, Nelson E., additional, and Imler, Jean-Luc, additional

Published
2020
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8. 2’3’-cGAMP triggers a STING and NF-κB dependent broad antiviral response in Drosophila

Author

Cai, Hua, primary, Holleufer, Andreas, additional, Simonsen, Bine, additional, Schneider, Juliette, additional, Lemoine, Aurélie, additional, Gad, Hans-Henrik, additional, Huang, Jingxian, additional, Huang, Jieqing, additional, Chen, Di, additional, Peng, Tao, additional, Marques, João T., additional, Hartmann, Rune, additional, Martins, Nelson, additional, and Imler, Jean-Luc, additional

Published
2019
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10. Single Cell Analysis of the Fate of Injected Oncogenic RasV12 Cells in Adult Wild Type Drosophila

Author

Chen, Di, Lan, Xiao, Huang, Xiaoming, Huang, Jieqing, Zhou, Xiaojing, Miao, Zhichao, Ma, Yuting, Goto, Akira, Ji, Shanming, and Hoffmann, Jules A.

Abstract

We have injected dish-cultured oncogenic RasV12 cells into adult male flies and analyzed by single cell transcriptomics their destiny within the host after 11 days. We identified in the preinjection samples and in the 11-day postinjection samples in all 16 clusters of cells, of which 5 disappeared during the experiment in the host. The other cell clusters expanded and expressed genes involved in the regulation of cell cycle, metabolism, and development. In addition, three clusters expressed genes related to inflammation and defense. Predominant among these were genes coding for phagocytosis and/or characteristic for plasmatocytes (the fly equivalent of macrophages). A pilot experiment indicated that the injection into flies of oncogenic cells, in which two of most strongly expressed genes had been previously silenced by RNA interference, into flies resulted in a dramatic reduction of their proliferation in the host flies as compared to controls. As we have shown earlier, the proliferation of the injected oncogenic cells in the adult flies is a hallmark of the disease and induces a wave of transcriptions in the experimental flies. We hypothesize that this results from a bitter dialogue between the injected cells and the host, while the experiments presented here should contribute to deciphering this dialogue.

Published
2022
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