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9 results on '"Huang, Sheng‐Dian"'

4. Alkaloids with Different Carbon Units from Myrioneuron faberi

Author

Cao, Ming-Ming, primary, Zhang, Yu, additional, Huang, Sheng-Dian, additional, Di, Ying-Tong, additional, Peng, Zong-Gen, additional, Jiang, Jian-Dong, additional, Yuan, Chun-Mao, additional, Chen, Duo-Zhi, additional, Li, Shun-Lin, additional, He, Hong-Ping, additional, and Hao, Xiao-Jiang, additional

Published
2015
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9. Myrifabine, the first dimeric Myrioneuron alkaloid from Myrioneuron faberi.

Author

Cao MM, Huang SD, Di YT, Yuan CM, Zuo GY, Gu YC, Zhang Y, and Hao XJ

Subjects
Alkaloids pharmacology, Anti-Infective Agents chemistry, Anti-Infective Agents pharmacology, Antineoplastic Agents, Phytogenic pharmacology, Crystallography, X-Ray, Drug Screening Assays, Antitumor, Methicillin-Resistant Staphylococcus aureus drug effects, Microbial Sensitivity Tests, Molecular Conformation, Molecular Structure, Nuclear Magnetic Resonance, Biomolecular, Staphylococcus aureus drug effects, Vancomycin pharmacology, Alkaloids chemistry, Alkaloids isolation & purification, Anti-Infective Agents isolation & purification, Antineoplastic Agents, Phytogenic chemistry, Antineoplastic Agents, Phytogenic isolation & purification, Rubiaceae chemistry
Abstract

One Myrioneuron alkaloid, myrifabine (1), the first example of a dimer with 12 chiral centers embraced in a decacyclic novel skeleton, was isolated from Myrioneuron faberi . Its structure was elucidated by spectroscopic data and single-crystal X-ray diffraction. The antimicrobial and cytotoxic activities of 1 were evaluated in vitro.

Published
2014
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