321 results on '"Huang, Yanming"'
Search Results
2. Association between stress hyperglycemia ratio with short-term and long-term mortality in critically ill patients with ischemic stroke
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Pan, Haowei, Xiong, Yiqun, Huang, Yanming, Zhao, Jie, and Wan, Haifang
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- 2024
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3. Stability enhancement of femtosecond optical parametric oscillator based on dispersion management
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Tong, Hui, Wang, Hua, Tian, Wenlong, Li, Qian, Tian, Xuan, Huang, Yanming, Zhu, Jiangfeng, and Wei, Zhiyi
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- 2024
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4. Clinical application of targeted next-generation sequencing in severe pneumonia: a retrospective review
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Zhang, Peng, Liu, Baoyi, Zhang, Shuang, Chang, Xuefei, Zhang, Lihe, Gu, Dejian, Zheng, Xin, Chen, Jiaqing, Xiao, Saiyin, Wu, Zhentao, Cai, Xuemin, Long, Mingfa, Lu, Wenjie, Zheng, Mingzhu, Chen, Rongrong, Gao, Rui, Zheng, Yan, Wu, Jinhua, Feng, Qiujuan, He, Gang, Chen, Yantang, Zheng, Weihao, Zuo, Wanli, Huang, Yanming, and Zhang, Xin
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- 2024
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5. Crustal Structure of the Jurassic Quiet Zone in the West Pacific Ocean: Insights from 2D Multichannel Seismic Reflection Profiles
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Yang, Xiaodong, Lin, Jingxue, Zhang, Jinchang, Luo, Yiming, Zhang, Xubo, Qin, Zhen, and Huang, Yanming
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- 2023
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6. Design and simulation of a compact plasmonic photonic crystal fiber filter with wide band and high extinction ratio
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Chen, Nan, Guo, Luhao, Xu, Yiming, Huang, Yanming, Ding, Xin, Xu, Yiran, Wang, Luyao, Liu, Chenxun, Wu, Tiancheng, Zhu, Yuxin, and She, Yuhe
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- 2024
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7. Central retinal artery occlusion without cherry-red spots
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Fan, Wei, Huang, Yanming, Zhao, Yuancheng, and Yuan, Rongdi
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- 2023
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8. Oral VV116 versus placebo in patients with mild-to-moderate COVID-19 in China: a multicentre, double-blind, phase 3, randomised controlled study
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Fan, Xiaohong, Dai, Xiahong, Ling, Yun, Wu, Lihua, Tang, Lingling, Peng, Chunxian, Huang, Chaolin, Liu, Hongyan, Lu, Hongzhou, Shen, Xinghua, Zhang, Wei, Wang, Furong, Li, Guangming, Li, Ming, Huang, Yanming, Zhang, Hongying, Li, Minghui, Ren, Fei, Li, Yuanyuan, Liu, Chenfan, Zhou, Zhiguo, Sun, Wei, Yi, Yongxiang, Zhou, Daming, Gao, Hainv, Pan, Qi, Liu, Hongde, Zhao, Jiang, Ding, Zhen, Ma, Yingmin, Li, Wei, Wang, Quanhong, Wang, Xicheng, Bai, Yichun, Jiang, Xiangao, Ma, Juan, Xie, Bingying, Zhang, Kui, and Li, Lanjuan
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- 2024
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9. Leritrelvir for the treatment of mild or moderate COVID-19 without co-administered ritonavir: a multicentre randomised, double-blind, placebo-controlled phase 3 trialResearch in context
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Yangqing Zhan, Zhengshi Lin, Jingyi Liang, Ruilin Sun, Yueping Li, Bingliang Lin, Fangqi Ge, Ling Lin, Hongzhou Lu, Liang Su, Tianxin Xiang, Hongqiu Pan, Chaolin Huang, Ying Deng, Furong Wang, Ruhong Xu, Dexiong Chen, Ping Zhang, Jianlin Tong, Xifu Wang, Qingwei Meng, Zhigang Zheng, Shuqiang Ou, Xiaoyun Guo, Herui Yao, Tao Yu, Weiyang Li, Yu Zhang, Mei Jiang, Zhonghao Fang, Yudi Song, Ruifeng Chen, Jincan Luo, Changyuan Kang, Shiwei Liang, Haijun Li, Jingping Zheng, Nanshan Zhong, Zifeng Yang, Huang Yanming, M.M, Dong Haiping, M.D., Jinlin Hou, M.M, Shao Lei, M.D., Li Xiaoguang, M.D., and Gao Yan, M.M.
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Anti SARS-CoV-2 drug ,Mono-therapy ,COVID-19 ,Drug-drug interaction ,RCT ,Medicine (General) ,R5-920 - Abstract
Summary: Background: Leritrelvir is a novel α-ketoamide based peptidomimetic inhibitor of SARS-CoV-2 main protease. A preclinical study has demonstrated leritrelvir poses similar antiviral activities towards different SARS-CoV-2 variants compared with nirmatrelvir. A phase 2 clinical trial has shown a comparable antiviral efficacy and safety between leritrelvir with and without ritonavir co-administration. This trial aims to test efficacy and safety of leritrelvir monotherapy in adults with mild-to-moderate COVID-19. Methods: This was a randomised, double-blind, placebo-controlled, multicentre phase 3 trial at 29 clinical sites in China. Enrolled patients were from 18 to 75 years old, diagnosed with mild or moderate COVID-19 and not requiring hospitalization. Patients had a positive SARS-CoV-2 nucleic acid test (NAT) and at least one of the COVID-19 symptoms within 48 h before randomization, and the interval between the first positive SARS-CoV-2 NAT and randomization was ≤120 h (5 days). Patients were randomly assigned in a 1:1 ratio to receive a 5-day course of either oral leritrelvir 400 mg TID or placebo. The primary efficacy endpoint was the time from the first dose to sustained clinical recovery of all 11 symptoms (stuffy or runny nose, sore throat, shortness of breath or dyspnea, cough, muscle or body aches, headache, chills, fever ≥37 °C, nausea, vomiting, and diarrhea). The safety endpoint was the incidence of adverse events (AE). Primary and safety analyses were performed in the intention-to-treat (ITT) population. This study is registered with ClinicalTrials.gov, NCT05620160. Findings: Between Nov 12 and Dec 30, 2022 when the zero COVID policy was abolished nationwide, a total of 1359 patients underwent randomization, 680 were assigned to leritrelvir group and 679 to placebo group. The median time to sustained clinical recovery in leritrelvir group was significantly shorter (251.02 h [IQR 188.95–428.68 h]) than that of Placebo (271.33 h [IQR 219.00–529.63 h], P = 0.0022, hazard ratio [HR] 1.20, 95% confidence interval [CI], 1.07–1.35). Further analysis of subgroups for the median time to sustained clinical recovery revealed that (1) subgroup with positive viral nucleic acid tested ≤72 h had a 33.9 h difference in leritrelvir group than that of placebo; (2) the subgroup with baseline viral load >8 log 10 Copies/mL in leritrelvir group had 51.3 h difference than that of placebo. Leritrelvir reduced viral load by 0.82 log10 on day 4 compared to placebo. No participants in either group progressed to severe COVID-19 by day 29. Adverse events were reported in two groups: leritrelvir 315 (46.46%) compared with placebo 292 (43.52%). Treatment-relevant AEs were similar 218 (32.15%) in the leritrelvir group and 186 (27.72%) in placebo. Two cases of COVID-19 pneumonia were reported in placebo group, and one case in leritrelvir group, none of them were considered by the investigators to be leritrelvir related. The most frequently reported AEs (occurring in ≥5% of participants in at least one group) were laboratory finding: hypertriglyceridemia (leritrelvir 79 [11.7%] vs. placebo 70 [10.4%]) and hyperlipidemia (60 [8.8%] vs. 52 [7.7%]); all of them were nonserious. Interpretation: Leritrelvir monotherapy has good efficacy for mild-to-moderate COVID-19 and without serious safety concerns. Funding: This study was funded by the National Multidisciplinary Innovation Team Project of Traditional Chinese Medicine, Guangdong Science and Technology Foundation, Guangzhou Science and Technology Planning Project and R&D Program of Guangzhou Laboratory.
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- 2024
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10. Personalized Recommendation System of College Students’ Employment Education Resources Based on Cloud Platform
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Wang, Fei, Huang, Yanming, Ma, Qinghui, Akan, Ozgur, Editorial Board Member, Bellavista, Paolo, Editorial Board Member, Cao, Jiannong, Editorial Board Member, Coulson, Geoffrey, Editorial Board Member, Dressler, Falko, Editorial Board Member, Ferrari, Domenico, Editorial Board Member, Gerla, Mario, Editorial Board Member, Kobayashi, Hisashi, Editorial Board Member, Palazzo, Sergio, Editorial Board Member, Sahni, Sartaj, Editorial Board Member, Shen, Xuemin, Editorial Board Member, Stan, Mircea, Editorial Board Member, Jia, Xiaohua, Editorial Board Member, Zomaya, Albert Y., Editorial Board Member, Fu, Weina, editor, and Sun, Guanglu, editor
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- 2022
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11. Traumatic Globe Luxation
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Zhang, Wei, Huang, Yanming, Li, Haibo, Liu, Yuanyuan, Yan, Hua, and Yan, Hua, Series Editor
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- 2022
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12. Effects of aerobic exercise on tear secretion and tear film stability in dry eye patients
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Sun, Chao, Chen, Xiaofan, Huang, Yanming, Zou, Huan, Fan, Wei, Yang, Mei, and Yuan, Rongdi
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- 2022
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13. ARHGEF37 overexpression promotes extravasation and metastasis of hepatocellular carcinoma via directly activating Cdc42
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Zhang, Xin, Ren, Liangliang, Wu, Junhua, Feng, Rongni, Chen, Yunyang, Li, Ronggang, Wu, Meimei, Zheng, Mingzhu, Wu, Xing Gui, Luo, Wanjun, He, Hongle, Huang, Yanming, Tang, Miaoling, and Li, Jun
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- 2022
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14. Nomogram model predicts the risk of visual impairment in diabetic retinopathy: a retrospective study
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Zhao, Yuancheng, Yu, Rentao, Sun, Chao, Fan, Wei, Zou, Huan, Chen, Xiaofan, Huang, Yanming, and Yuan, Rongdi
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- 2022
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15. Traumatic Globe Luxation
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Zhang, Wei, primary, Huang, Yanming, additional, Li, Haibo, additional, Liu, Yuanyuan, additional, and Yan, Hua, additional
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- 2021
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16. The correlation between the expression of Smad2/3 and Smad7 proteins in blood neutrophils and asthma disease
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HUANG, Chaowen, primary, PENG, Ming, additional, ZHONG, Xueying, additional, TONG, Jinzhai, additional, LIU, Lingyun, additional, and HUANG, Yanming, additional
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- 2024
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17. Methylation silencing and reactivation of exogenous genes in lentivirus-mediated transgenic mice
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Wen, Jinkun, Wu, Jinni, Cao, Tianqi, Zhi, Shengyao, Chen, Yuxi, Aagaard, Lars, Zhen, Peilin, Huang, Yanming, Zhong, Jianxin, and Huang, Junjiu
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- 2021
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18. Pan-cancer analysis of homeodomain-containing gene C10 and its carcinogenesis in lung adenocarcinoma
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Tan, Xiangyuan, primary, Li, Zhanzhan, additional, Xie, Huayan, additional, Chen, Jiarong, additional, Xiao, Jian, additional, Zhi, Yaofeng, additional, Mo, Haixin, additional, Huang, Yanming, additional, and Liu, Aibin, additional
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- 2023
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19. Patterns of Structural Changes in the Fundus Measured by Optical Coherence Tomography Angiography as Potential Markers of Acute Mountain Sickness
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Zhao, Yuancheng, primary, Zou, Huan, additional, Fan, Wei, additional, Liu, Yuqi, additional, Chen, Xiaofan, additional, Huang, Yanming, additional, and Yuan, Rongdi, additional
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- 2023
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20. Axon regeneration after optic nerve injury in rats can be improved via PirB knockdown in the retina
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Yang, Mei, Jian, Lan, Fan, Wei, Chen, Xing, Zou, Huan, Huang, Yanming, Chen, Xiaofan, Zhou, Yuan-Guo, and Yuan, Rongdi
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- 2021
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21. Forgery detection of motion compensation interpolated frames based on discontinuity of optical flow
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Ding, Xiangling, Huang, Yanming, Li, Yue, and He, Jiale
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- 2020
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22. Broadband Polarization Beam Splitter Based on Silicon Dual-Core Photonic Crystal Fiber with Gold Layers Operating in Mid-Infrared Band
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Chen, Nan, primary, Ding, Xin, additional, Wang, Luyao, additional, Xiao, Yunpeng, additional, Guo, Wenhui, additional, Huang, Yanming, additional, Guo, Luhao, additional, Liu, Chenxun, additional, and Xu, Yiming, additional
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- 2023
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23. Soluble E‐cadherin participates in BLM‐induced pulmonary fibrosis by promoting EMT and lung fibroblast migration
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Huang, Chaowen, primary, Liang, Congmin, additional, Tong, Jinzhai, additional, Zhong, Xueying, additional, Luo, Lishan, additional, Liang, Liping, additional, Wen, Yuting, additional, Zhong, Liandi, additional, Deng, Jiongrui, additional, Peng, Ming, additional, Wu, Weiliang, additional, Huang, Weijian, additional, Xie, Anlun, additional, Huang, Yanming, additional, and Chen, Jialong, additional
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- 2023
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24. Secondary Cones of the Shatsky Rise and Implications for Late-Stage Volcanism Atop Oceanic Plateaus
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Zhang, Jinchang, Chen, Jie, and Huang, Yanming
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- 2019
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25. Moho Structure of the Southwest Sub-Basin, South China Sea, from a Multichannel Seismic Reflection Profile NH973-1
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Zhang, Jinchang, Chen, Jie, and Huang, Yanming
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- 2019
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26. Oceanic plateau formation by seafloor spreading implied by Tamu Massif magnetic anomalies
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Sager, William W., Huang, Yanming, Tominaga, Masako, Greene, John A., Nakanishi, Masao, and Zhang, Jinchang
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- 2019
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27. The effect of different doses of simvastatin on autophagy and inflammation in asthmatic mice
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HUANG, Chaowen, primary, HUANG, Yile, additional, PENG, Ming, additional, ZHONG, Xueying, additional, TONG, Jinzhai, additional, and HUANG, Yanming, additional
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- 2023
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28. LINC00173.v1 promotes angiogenesis and progression of lung squamous cell carcinoma by sponging miR-511-5p to regulate VEGFA expression
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Chen, Jiarong, Liu, Aibin, Wang, Zhihui, Wang, Bin, Chai, Xingxing, Lu, Wenjie, Cao, Ting, Li, Ronggang, Wu, Minyan, Lu, Zhuming, Pang, Wenguang, Xiao, Lin, Chen, Xiangmeng, Zheng, Yan, Chen, Qiong, Zeng, Jincheng, Li, Jun, Zhang, Xin, Ren, Dong, and Huang, Yanming
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- 2020
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29. A case of bilateral endogenous endophthalmitis misdiagnosed as Purtscher’s retinopathy
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Huang, Yanming and Yuan, Rongdi
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- 2020
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30. Soluble E‐cadherin participates in BLM‐induced pulmonary fibrosis by promoting EMT and lung fibroblast migration.
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Huang, Chaowen, Liang, Congmin, Tong, Jinzhai, Zhong, Xueying, Luo, Lishan, Liang, Liping, Wen, Yuting, Zhong, Liandi, Deng, Jiongrui, Peng, Ming, Wu, Weiliang, Huang, Weijian, Xie, Anlun, Huang, Yanming, and Chen, Jialong
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PULMONARY fibrosis ,LUNGS ,FIBROBLASTS ,EPITHELIAL-mesenchymal transition ,BLEOMYCIN ,BRONCHOALVEOLAR lavage - Abstract
Soluble E‐cadherin (sE‐cad) is an 80 kDa fragment derived from E‐cadherin that is shed from the cell surface through proteolytic cleavage and is a biomarker in various cancers that promotes invasion and migration. Alveolar epithelial destruction, aberrant lung fibroblast migration and inflammation contribute to pulmonary fibrosis. Here, we hypothesized that E‐cadherin plays an important role in lung fibrosis. In this study, we found that E‐cadherin was markedly increased in the bronchoalveolar lavage fluid (BALF) and serum of mice with pulmonary fibrosis and that blocking sE‐cad with HECD‐1, a neutralizing antibody targeting the ectodomain of E‐cadherin, effectively inhibited myofibroblast accumulation and collagen deposition in the lungs after bleomycin (BLM) exposure. Moreover, transforming growth factor‐β (TGF‐β1) induced the shedding of sE‐cad from A549 cells, and treatment with HECD‐1 inhibited epithelial–mesenchymal transition (EMT) stimulated by TGF‐β1. Fc‐E‐cadherin (Fc‐Ecad), which is an exogenous form of sE‐cad, robustly promoted lung fibroblast migration. E‐cadherin participates in bleomycin (BLM)‐induced lung fibrosis by promoting EMT in the alveolar epithelium and fibroblast activation. E‐cadherin may be a novel therapeutic target for lung fibrosis. [ABSTRACT FROM AUTHOR]
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- 2024
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31. Numerical analysis of a compact all-fiber polarization beam splitter based on dual-core photonic crystal fiber with As2S3 thin layer
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Chen, Nan, Ding, Xin, Wang, Luyao, Xu, Yiming, Guo, Luhao, Huang, Yanming, Liu, Chenxun, Xu, Yiran, Guo, Wenhui, Xiao, Yunpeng, Yue, Wanglin, and She, Yuhe
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- 2024
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32. Ultrasound-guided suprainguinal fascia iliaca block combined with a sacral plexus block for lower extremity surgery: A case report
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Zhao, Jie, Huang, Yanming, Fu, Mingjie, and Tao, Fan
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- 2020
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33. Secreted S100A4 causes asthmatic airway epithelial barrier dysfunction induced by house dust mite extracts via activating VEGFA / VEGFR2 pathway
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Huang, Chaowen, primary, Zheng, Dongyan, additional, Fu, Chunlai, additional, Cai, Ziwei, additional, Zhang, He, additional, Xie, Zhefan, additional, Luo, Lishan, additional, Li, Huifang, additional, Huang, Yanming, additional, and Chen, Jialong, additional
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- 2023
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34. Circular RNA hsa_circ_0000690 as a potential biomarker for diagnosis and prognosis of intracranial aneurysm: Closely relating to the volume of hemorrhage
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Huang, Yanming, primary, Cao, Huimin, additional, Qi, Xiaolong, additional, Guan, Celin, additional, and Que, Shuanglin, additional
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- 2023
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35. Management and visual outcome of SCH in vitrectomized eye
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Huang, Yanming, Liao, Qiong, and Yuan, Rongdi
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- 2015
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36. Additional file 6 of Nomogram model predicts the risk of visual impairment in diabetic retinopathy: a retrospective study
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Zhao, Yuancheng, Yu, Rentao, Sun, Chao, Fan, Wei, Zou, Huan, Chen, Xiaofan, Huang, Yanming, and Yuan, Rongdi
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Additional file 6.
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- 2023
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37. Critical care admission following elective surgery was not associated with survival benefit: prospective analysis of data from 27 countries
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Kahan, Brennan C., Koulenti, Desponia, Arvaniti, Kostoula, Beavis, Vanessa, Campbell, Douglas, Chan, Matthew, Moreno, Rui, Pearse, Rupert M., Pearse, Rupert M., Beattie, Scott, Clavien, Pierre-Alain, Demartines, Nicolas, Fleisher, Lee A., Grocott, Mike, Haddow, James, Hoeft, Andreas, Holt, Peter, Moreno, Rui, Pritchard, Naomi, Rhodes, Andrew, Wijeysundera, Duminda, Wilson, Matt, Ahmed, Tahania, Everingham, Kirsty, Hewson, Russell, Januszewska, Marta, Pearse, Rupert M., Phull, Mandeep-Kaur, Halliwell, Richard, Shulman, Mark, Myles, Paul, Schmid, Werner, Hiesmayr, Michael, Wouters, Patrick, de Hert, Stefan, Lobo, Suzana, Beattie, Scott, Wijeysundera, Duminda, Fang, Xiangming, Rasmussen, Lars, Futier, Emmanuel, Biais, Matthieu, Venara, Aurélien, Slim, Karem, Sander, Michael, Koulenti, Despoina, Arvaniti, Kostoula, Chan, Mathew, Kulkarni, Atul, Chandra, Susilo, Tantri, Aida, Geddoa, Emad, Abbas, Muntadhar, Della Rocca, Giorgio, Sivasakthi, Datin, Mansor, Marzida, Luna, Pastor, Bouwman, Arthur, Buhre, Wolfgang, Beavis, Vanessa, Campbell, Douglas, Short, Tim, Osinaike, Tunde, Matos, Ricardo, Grigoras, Ioana, Kirov, Mikhail, Protsenko, Denis, Biccard, Bruce, Aldecoa, Cesar, Chew, Michelle, Hofer, Christoph, Hubner, Martin, Ditai, James, Szakmany, Tamas, Fleisher, Lee, Ferguson, Marissa, MacMahon, Michael, Shulman, Mark, Cherian, Ritchie, Currow, Helen, Kanathiban, Kathirgamanathan, Gillespie, David, Pathmanathan, Edward, Phillips, Katherine, Reynolds, Jenifer, Rowley, Joanne, Douglas, Jeanene, Kerridge, Ross, Currow, Helen, Garg, Sameer, Bennett, Michael, Jain, Megha, Alcock, David, Terblanche, Nico, Cotter, Rochelle, Leslie, Kate, Stewart, Marcelle, Zingerle, Nicolette, Clyde, Antony, Hambidge, Oliver, Rehak, Adam, Cotterell, Sharon, Binh QuanHuynh, Wilson, McCulloch, Timothy, Ben-Menachem, Erez, Egan, Thomas, Cope, Jennifer, Halliwell, Richard, Fellinger, Paul, Haselberger, Simone, Holaubek, Caroline, Lichtenegger, Paul, Scherz, Florian, Schmid, Werner, Hoffer, Franz, Cakova, Veronika, Eichwalder, Andreas, Fischbach, Norbert, Klug, Reinhold, Schneider, Elisabeth, Vesely, Martin, Wickenhauser, Reinhart, Grubmueller, Karl Gernot, Leitgeb, Marion, Lang, Friedrich, Toro, Nancy, Bauer, Marlene, Laengle, Friedrich, Mayrhofer, Thomas, Buerkle, Christian, Forstner, Karin, Germann, Reinhard, Rinoesl, Harald, Schindler, Elke, Trampitsch, Ernst, Fritsch, Gerhard, Szabo, Christian, Bidgoli, Jawad, Verdoodt, Hans, Forget, Patrice, Kahn, David, Lois, Fernande, Momeni, Mona, Prégardien, Caroline, Pospiech, Audrey, Steyaert, Arnaud, Veevaete, Laurent, De Kegel, Dirk, De Jongh, Karen, Foubert, Luc, Smitz, Carine, Vercauteren, Marcel, Poelaert, Jan, Van Mossevelde, Veerle, Abeloos, Jacques, Bouchez, Stefaan, Coppens, Marc, De Baerdemaeker, Luc, Deblaere, Isabel, De Bruyne, Ann, De Hert, Stefan, Fonck, Kristine, Heyse, Bjorn, Jacobs, Tom, Lapage, Koen, Moerman, Anneliese, Neckebroek, Martine, Parashchanka, Aliaksandra, Roels, Nathalie, Van Den Eynde, Nancy, Vandenheuvel, Michael, Van Limmen, Jurgen, Vanluchene, Ann, Vanpeteghem, Caroline, Wouters, Patrick, Wyffels, Piet, Huygens, Christel, Vandenbempt, Punitha, Van de Velde, Marc, Dylst, Dimitri, Janssen, Bruno, Schreurs, Evelien, Aleixo, Fábia Berganton, Candido, Keulle, Dias Batista, Hugo, Guimarães, Mario, Guizeline, Jaqueline, Hoffmann, João, Lobo, Suzana M., Lobo, Francisco Ricardo, Nascimento, Vinícius, Nishiyama, Katia, Pazetto, Lucas, Souza, Daniela, Souza Rodrigues, Rodrigo, Vilela dos Santos, Ana Maria, Jardim, Jaquelline, Silva, Joao, do NascimentoJunior, Paulo, Baio, Thalissa Hermínia, Pereira de Castro, Gabriel Isaac, Watanabe Oliveira, Henri Roger, Amendola, Cristina Prata, Cardoso, Gutemberg, Ortega, Daniela, Brotto, Ana Flavia, De Oliveira, Mirella Cristine, Réa-Neto, Álvaro, Dias, Fernando, Azambuja, Pedro, Knibel, Marcos Freitas, Martins, Antonio, Almeida, William, Neto, Calim Neder, Tardelli, Maria Angela, Caser, Eliana, Machado, Marcio, Aguzzoli, Crisitiano, Baldisserotto, Sérgio, Beck Tabajara, Fernanda, Bettega, Fernanda, Rodrigues Júnior, La Hore Correa, de Gasperi, Julia, Faina, Lais, Nolasco, Marcos Farias, da Costa Fischer, Bruna Ferreira, de Campos Ferreira, Mariana Fosch, Hartmann, Cristina, Kliemann, Marta, Ribeiro, Gustavo LuisHubert, Fraga, Julia Merladete, Netto, Thiago Motta, Pozza, Laura Valduga, Wendling, Paulo Rafael, Azevedo, Caroline, Garcia, Juliana, Lopes, Marcel, Maia, Bernardo, Maselli, Paula, Melo, Ralph, Mendes, Weslley, Neves, Matheus, Ney, Jacqueline, Piras, Claudio, Applewhaite, Christopher, Carr, Adrienne, Chow, Lorraine, Duttchen, Kaylene, Foglia, Julena, Greene, Michael, Hinther, Ashley, Houston, Kendra, McCormick, Thomas Jared, Mikhayel, Jennifer, Montasser, Sam, Ragan, Alex, Suen, Andrew, Woolsey, Adrianna, Yu, Hai Chuan, Funk, Duane, Kowalski, Stephen, Legaspi, Regina, McDonald, Heather, Siddiqui, Faisal, Pridham, Jeremy, Rowe, Bernadette, Sampson, Sonia, Thiessen, Barton, Zbitnew, Geoff, Bernard, Andre, George, Ronald, Jones, Philip, Moor, Rita, Siddiqui, Naveed, Wolfer, Alexandra, Tran, Diem, Winch, Denyse, Dobson, Gary, Hinther, Ashley, McCormick, Thomas, Montasser, Osama, Suen, Andrew, Woolsey, Adrianna, Bernard, Andre, George, Ronald, Hall, Richard, Bernard, Andre, George, Ronald, Hall, Richard, Applewhaite, Christopher, Baghirzada, Leyla, McCormick, Thomas Jared, Suen, Andrew, Dai, Si Yuan, Hare, Gregory, Lee, Esther, Shastri, Uma, Tsui, Albert, Yagnik, Anmol, Alvares, Danielle, Choi, Stephen, Dwyer, Heather, Flores, Kathrina, McCartney, Colin, Somascanthan, Priya, Beattie, Scott, Carroll, Jo, Pazmino-Canizares, Janneth, Wijeysundera, Duminda, Wolfer, Alexandra, Ami, Noam, Chan, Vincent, Perlas, Anahi, Argue, Ruth, Lavis, Katie, Mayson, Kelly, Cao, Ying, Gao, Hong, hu, tingju, Lv, Jie, Yang, Jian, Yang, Yang, Zhong, Yi, Zhou, Jing, Zou, Xiaohua, He, Miao, Li, Xiaoying, Luo, Dihuan, Wang, Haiying, Yu, Tian, Chen, Liyong, Wang, Lijun, Cai, Yunfei, Cao, Zhongming, Li, Yanling, Lian, Jiaxin, Sun, Haiyun, Wang, Sheng, Wang, Zhipeng, Wang, Kenru, Zhu, Yi, Du, Xindan, Fan, Hao, Fu, Yunbin, Huang, Lixia, Huang, Yanming, Hwan, Haifang, Luo, Hong, Qu, Pi-Sheng, Tao, Fan, Wang, Zhen, Wang, Guoxiang, Wang, Shun, Zhang, Yan, Zhang, Xiaolin, Chen, Chao, Wang, Weixing, Liu, Zhengyuan, Fan, Lihua, Tang, Jing, Chen, Yijun, Chen, Yongjie, Han, Yangyang, Huang, Changshun, Liang, Guojin, Shen, Jing, Wang, Jun, Yang, Qiuhong, Zhen, Jungang, Zhou, Haidong, Chen, Junping, Chen, Zhang, Li, Xiaoyu, Meng, Bo, Ye, Haiwang, Zhang, Xiaoyan, Bi, Yanbing, Cao, Jianqiao, Guo, Fengying, Lin, Hong, Liu, Yang, Lv, Meng, Shi, Pengcai, Song, Xiumei, Sun, Chuanyu, Sun, Yongtao, Wang, Yuelan, Wang, Shenhui, Zhang, Min, Chen, Rong, Hou, Jiabao, Leng, Yan, Meng, Qing-tao, Qian, Li, Shen, Zi-ying, Xia, Zhong-yuan, Xue, Rui, Zhang, Yuan, Zhao, Bo, Zhou, Xian-jin, Chen, Qiang, Guo, Huinan, Guo, Yongqing, Qi, Yuehong, Wang, Zhi, Wei, Jianfeng, Zhang, Weiwei, Zheng, Lina, Bao, Qi, Chen, Yaqiu, Chen, 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Vasian, Horatiu, Manga, Gratiela, Stefan, Andreea, Tomescu, Dana, Filipescu, Daniela, Paunescu, Marilena-Alina, Stefan, Mihai, Stoica, Radu, Gavril, Laura, Pătrăşcanu, Emilia, Ristescu, Irina, Rusu, Daniel, Diaconescu, Ciresica, Iosep, Gabriel Florin, Pulbere, Dorin, Ursu, Irina, Balanescu, Andreea, Grintescu, Ioana, Mirea, Liliana, Rentea, Irina, Vartic, Mihaela, Lupu, Mary-Nicoleta, Stanescu, Dorin, Streanga, Lavinea, Antal, Oana, Hagau, Natalia, Patras, Dumitru, Petrisor, Cristina, Tosa, Flaviu, Tranca, Sebastian, Copotoiu, Sanda Maria, Ungureanu, Liviu Lucian, Harsan, Cristian Remus, Papurica, Marius, Cernea, Daniela Denisa, Dragoescu, Nicoleta Alice, Aflori, Laura, Vaida, Carmen, Ciobotaru, Oana Roxana, Aignatoaie, Mariana, Carp, Cristina Paula, Cobzaru, Isabelle, Mardare, Oana, Purcarin, Bianca, Tutunaru, Valentin, Ionita, Victor, Arustei, Mirela, Codita, Anisoara, Busuioc, Mihai, Chilinciuc, Ion, Ciobanu, Cristina, Belciu, Ioana, Tincu, Eugen, Blaj, Mihaela, Grosu, 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Gray, Sophie, Hay, David, Mills, Sarah, Montgomery, Jane, Riddell, Rory, Simpson, James, Bhardwaj, Neeraj, Paul, Elaine, Uwubamwen, Nosakhare, Vohra, Akbar, Berntsen, Emer, Nolan, Tracey, Turner, Angus, Alexander, Maini, Arrich, James, Arumugam, Swarna, Blackwood, Douglas, Boggiano, Victoria, Brown, Robyn, Lam Chan, Yik, Chatterjee, Devnandan, Chhabra, Ashok, Christian, Rachel, Costelloe, Hannah, CoxwellMatthewman, Madeline, Dalton, Emma, Darko, Julia, Davari, Maria, Dave, Tejal, Deacon, Matthew, Deepak, Shantal, Edmond, Holly, Ellis, Jessica, El-Sayed, Ahmed, Eneje, Philip, English, Rose, Ewe, Renee, Foers, William, Franklin, John, Gallego, Laura, Garrett, Emily, Goldberg, Olivia, Goss, Harry, Greaves, Rosanna, Harris, Rudy, Hennings, Charles, Jones, Eleanor, Kamali, Nelson, Kokkinos, Naomi, Lewis, Carys, Lignos, Leda, Malgapo, Evaleen Victoria, Malik, Rizwana, Milne, Andrew, Mulligan, John-Patrick, Nicklin, Philippa, Palipane, Natasha, Parsons, Thomas, Piper, Rebecca, Prakash, Rohan, Ramesh, Byron, Rasip, Sarah, Reading, Jacob, Rela, Mariam, Reyes, Anna, Robert, Stephens, Rooms, Martin, Shah, Karishma, Simons, Henry, Solanki, Shalil, Spowart, Emma, Stevens, Amy, Thomas, Christopher, Waggett, Helena, Yassaee, Arrash, Kennedy, Anthony, Scott, Sara, Somanath, Sameer, Berg, Andrew, Hernandez, Miguel, Nanda, Rajesh, Tank, Ghanshyambhai, Wilson, Natalie, Wilson, Debbie, Al-Soudaine, Yassr, Baldwin, Matthew, Cornish, Julie, Davies, Zoe, Davies, Leigh, Edwards, Marc, Frewer, Natasha, Gallard, Sian, Glasbey, James, Harries, Rhiannon, Hopkins, Luke, Kim, Taeyang, Koompirochana, Vilavan, Lawson, Simon, Lewis, Megan, Makzal, Zaid, Scourfield, Sarah, Ahmad, Yousra, Bates, Sarah, Blackwell, Clare, Bryant, Helen, Coulter, Suzanne, Cruickshank, Ross, Daniel, Sonya, Daubeny, Thomas, Edwards, Mark, Golder, Kim, Hawkins, Lesley, Helen, Bryant, Hinxman, Honor, Levett, Denny, Skinner, Ben, Walsgrove, Joseph, Bradburn, Mike, Dickson, Jane, Constantin, Kathryn, Karen, Markwell, O’Brien, Peter, O’Donohoe, Lynn, Payne, Hannah, Sundayi, Saul, Walker, Elaine, Brooke, Jenny, Cardy, Jon, Humphreys, Sally, Kessack, Laura, Kubitzek, Christiane, Kumar, Suhas, Cotterill, Donna, Hodzovic, Emil, Hosdurga, Gurunath, Miles, Edward, Saunders, Glenn, Campbell, Marta, Chan, Peter, Jemmett, Kim, Raj, Ashok, Naik, Aditi, Ramamoorthy, Rajarajan, Shah, Nimesh, Sylvan, Axel, Blyth, Katharine, Burtenshaw, Andrew, Freeman, David, Johnson, Emily, Lo, Philip, Martin, Terry, Plunkett, Emma, Wollaston, Julie, Allison, Joanna, Carroll, Christine, Craw, Nicholas, Craw, Sarah, Pitt-Kerby, Tressy, Rowland-Axe, Rebecca, Spurdle, Katie, McDonald, Andrew, Simon, Davies, Sinha, Vivek, Smith, Thomas, Banner-Goodspeed, Valerie, Boone, Myles, Campbell, Kathleen, Lu, Fengxin, Scannell, Joseph, Sobol, Julia, Balajonda, Naraida, Clemmons, Karen, Conde, Carlos, Funk, Bonita, Hall, Roger, Hopkins, Thomas, Olaleye, Omowunmi, Omer, Omer, Pender, Michelle, Porto, Angelo, Stevens, Alice, Waweru, Peter, Yeh, Erlinda, Bodansky, Daniella, Evans, Adam, Kleopoulos, Steven, Maril, Robert, Mathney, Edward, Sanchez, Angela, Tinuoye, Elizabeth, Bateman, Brian, Eng, Kristen, Jiang, Ning, Ladha, Karim, Needleman, Joseph, Chen, Lee-lynn, Chen, Lee-lynn, Lane, Rondall, Robinowitz, David, Ghushe, Neil, Irshad, Mariam, Patel, Samir, Takemoto, Steven, Wallace, Art, Mazzeffi, Michael, Rock, Peter, Wallace, Karin, Zhu, Xiaomao, Chua, Pandora, Fleisher, Lee, Mattera, Matthew, Sharar, Rebecca, Thilen, Stephan, Treggiari, Miriam, Morgan, Angela, Sofjan, Iwan, Subramaniam, Kathirvel, Avidan, Michael, Maybrier, Hannah, Muench, Maxwell, Wildes, Troy, and The International Surgical Outcomes Study (ISOS) group
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- 2017
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38. Adaptive model-parameter-free nonsingular fixed-time sliding mode control for underwater cleaning vehicle
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Chen, Hongxuan, primary, Tang, Guoyuan, additional, Huang, Yanming, additional, Wang, Jianjun, additional, and Huang, Hui, additional
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- 2022
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39. Secreted S100A4 causes asthmatic airway epithelial barrier dysfunction induced by house dust mite extracts via activating VEGFA/VEGFR2 pathway.
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Huang, Chaowen, Zheng, Dongyan, Fu, Chunlai, Cai, Ziwei, Zhang, He, Xie, Zhefan, Luo, Lishan, Li, Huifang, Huang, Yanming, and Chen, Jialong
- Subjects
HOUSE dust mites ,AIRWAY (Anatomy) ,CARRIER proteins ,BRONCHOALVEOLAR lavage ,CELLULAR signal transduction ,LUNGS ,IMMUNOGLOBULINS - Abstract
The airway epithelial barrier dysfunction plays a crucial role in pathogenesis of asthma and causes the amplification of downstream inflammatory signal pathway. S100 calcium binding protein A4 (S100A4), which promotes metastasis, have recently been discovered as an effective inflammatory factor and elevated in bronchoalveolar lavage fluid in asthmatic mice. Vascular endothelial growth factor‐A (VEGFA), is considered as vital regulator in vascular physiological activities. Here, we explored the probably function of S100A4 and VEGFA in asthma model dealt with house dust mite (HDM) extracts. Our results showed that secreted S100A4 caused epithelial barrier dysfunction, airway inflammation and the release of T‐helper 2 cytokines through the activation of VEGFA/VEGFR2 signaling pathway, which could be partial reversed by S100A4 polyclonal antibody, niclosamide and S100A4 knockdown, representing a potential therapeutic target for airway epithelial barrier dysfunction in asthma. [ABSTRACT FROM AUTHOR]
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- 2023
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40. Identifying Topics and Evolutionary Trends of Literature on Brain Metastases Using Latent Dirichlet Allocation
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Chen, Jiarong, Williams, Matt, Huang, Yanming, and Si, Shijing
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Biochemistry, Genetics and Molecular Biology (miscellaneous) ,Molecular Biology ,Biochemistry - Abstract
Research on brain metastases kept innovating. We aimed to illustrate what topics the research focused on and how it varied in different periods of all the studies on brain metastases with topic modelling. We used the latent Dirichlet allocation model to analyse the titles and abstracts of 50,176 articles on brain metastases retrieved from Web of Science, Embase and MEDLINE. We further stratified the articles to find out the topic trends of different periods. Our study identified that a rising number of studies on brain metastases were published in recent decades at a higher rate than all cancer articles. Overall, the major themes focused on treatment and histopathology. Radiotherapy took over the first and third places in the top 20 topics. Since the 2010’s, increasing attention concerned about gene mutations. Targeted therapy was a popular topic of brain metastases research after 2020.
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- 2022
41. Genetic characterization and evolution of H6N6 subtype avian influenza viruses
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Cui, Mingxian, primary, Huang, Yanming, additional, Wang, Xingbo, additional, Bian, Xiyi, additional, Du, Liuyang, additional, Yan, Yan, additional, Gu, Jinyan, additional, Dong, Weiren, additional, Zhou, Jiyong, additional, and Liao, Min, additional
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- 2022
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42. Pulmonary Microbial Composition in Sepsis-Induced Acute Respiratory Distress Syndrome
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Zhang, Peng, primary, Liu, Baoyi, additional, Zheng, Weihao, additional, Chen, Yantang, additional, Wu, Zhentao, additional, Lu, Yuting, additional, Ma, Jie, additional, Lu, Wenjie, additional, Zheng, Mingzhu, additional, Wu, Wanting, additional, Meng, Zijie, additional, Wu, Jinhua, additional, Zheng, Yan, additional, Zhang, Xin, additional, Zhang, Shuang, additional, and Huang, Yanming, additional
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- 2022
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43. Nomogram model predicts the risk of visual impairment in diabetic retinopathy: a retrospective study
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Zhao, Yuancheng, primary, Yu, Rentao, additional, Sun, Chao, additional, Fan, Wei, additional, Zou, Huan, additional, Chen, Xiaofan, additional, Huang, Yanming, additional, and Yuan, Rongdi, additional
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- 2022
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44. Volume of Aneurysmal Subarachnoid Hematoma Measured Quantitatively by 3D Slicer to Predict Symptomatic Cerebral Vasospasm.
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Huang Yanming, Lai Xiaoyan, Guan Celin, Qi Xiaolong, Li Huihua, Lin Xin, and Que Shuanglin
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- *
CEREBRAL vasospasm , *HEMATOMA , *ONE-way analysis of variance , *LOGISTIC regression analysis , *SUBARACHNOID hemorrhage - Abstract
Background and Objectives: Aneurysmal subarachnoid hemorrhage is strongly associated with symptomatic cerebral vasospasm. This study aims to investigate whether a quantitative measure of aneurysmal subarachnoid hematoma by 3D Slicer is more valuable for vasospasm risk prediction compared with modified Fisher scale and the new scale by Eagles. Materials and Methods: We performed a retrospective research of Digital Imaging and Communications in Medicine format (DICOM) in aneurysmal patients treated at our institution from 2019 to 2020. Association between vasospasm and hematoma volume by 3D Slicer was explored by univariate and multivariate analyses. Value of risk prediction was compared through area under the receiver operator characteristic curve (AUC) among the modified Fisher scale, the new scale by Eagles, and hematoma volume by 3D Slicer. Results: Hematoma volume by 3D Slicer had a significant relationship with vasospasm both by one‑way analysis of variance (ANOVA; F = 19.37, P < 0.001) and a binary logistic regression analysis (odds ratio [OR] = 1.05, P = 0.016). Hematoma volume by 3D Slicer had a significantly higher AUC (0.708; 95% confidence interval [CI]: 0.618–0.798, P < 0.001) than the modified Fisher scale and the new scale by Eagles. The optimal diagnostic threshold for hematoma volume by 3D Slicer was 15.98 ml, and the sensitivity and specificity were 73.5% and 58.6%, respectively. Conclusions: Volume of aneurysmal subarachnoid hematoma measured quantitatively by 3D Slicer can improve the predictive value for symptomatic cerebral vasospasm. [ABSTRACT FROM AUTHOR]
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- 2023
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45. Giant dielectric response and charge compensation of Li- and Co-doped NiO ceramics
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Li, Yunhua, Fang, Liang, Liu, Laijun, Huang, Yanming, and Hu, Changzheng
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- 2012
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46. Proteomics and phosphoproteomics analysis of vitreous in idiopathic epiretinal membrane patients
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Sun, Chao, primary, Zou, Huan, additional, Yang, Zhouquan, additional, Yang, Mei, additional, Chen, Xiaofan, additional, Huang, Yanming, additional, Fan, Wei, additional, and Yuan, Rongdi, additional
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- 2022
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47. Vitamin D ameliorates asthma‐induced lung injury by regulating HIF‐1α/Notch1 signaling during autophagy
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Huang, Chaowen, primary, Peng, Ming, additional, Tong, Jinzhai, additional, Zhong, Xueying, additional, Xian, Jun, additional, Zhong, Liandi, additional, Deng, Jiongrui, additional, and Huang, Yanming, additional
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- 2022
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48. Additional file 1 of Effects of aerobic exercise on tear secretion and tear film stability in dry eye patients
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Sun, Chao, Chen, Xiaofan, Huang, Yanming, Zou, Huan, Fan, Wei, Yang, Mei, and Yuan, Rongdi
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genetic structures ,sense organs ,eye diseases - Abstract
Additional file 1. Ocular Surface Disease Index (OSDI). The OSDI is the most widely used questionnaire for dry eye clinical trials.
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- 2022
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49. Additional file 1 of ARHGEF37 overexpression promotes extravasation and metastasis of hepatocellular carcinoma via directly activating Cdc42
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Zhang, Xin, Ren, Liangliang, Wu, Junhua, Feng, Rongni, Chen, Yunyang, Li, Ronggang, Wu, Meimei, Zheng, Mingzhu, Wu, Xing Gui, Luo, Wanjun, He, Hongle, Huang, Yanming, Tang, Miaoling, and Li, Jun
- Abstract
Additional file 1: Table S1. Clinicopathological characteristics of studied patients and expression of ARHGEF37 in HCC. Table S2. Correlation between the clinicopathological features and expression of ARHGEF37. Table S3. Univariate and multivariate analysis of factors associated with Overall Survival in 365 HCC patients. Table S4. Univariate and multivariate analysis of factors associated with Metastasis-free Survival in 365 HCC patients. Table S5. Sequence of primers used for subcloning and plasmid construction. Table S6. Sequence of primers used for qPCR. Table S7. Sequence of Oligonucleotides for siRNAs. Figure S1. ARHGEF37 is upregulated in HCC. (a) Analysis of TCGA datasets showing that ARHGEF37 was upregulated in HCC tumor tissues compared with that in normal liver tissues (P < 0.001). Figure S2. ARHGEF37 overexpression promotes pulmonary metastasis in HCC. Figure S3. ARHGEF37 did not induce the overexpression of GTP-bound form of Rac1 and RhoA. Figure S4. ARHGEF37 facilitates invadopodia formation in tumor cells and disrupts the interaction between endothelial cells and pericytes. Figure S5. In vivo mouse experiments where tumors metastasis was tracked by bioluminescence imaging.
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- 2022
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50. Restoration Algorithm-Based Ultrasound Image in Evaluating the Effect of Dexmedetomidine on Patients with Neurological Disorder Anesthetized by Sevoflurane
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Yao, Yingying, primary, Sun, Zhihui, additional, Huang, Yanming, additional, Zhou, Xiaoqin, additional, and Xia, Daolin, additional
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- 2022
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