Search

Two undescribed sesamin-type sesquilignans ptehoosines A (1) and B (2), together with 4 known lignans (3–6), were isolated from Pterocephalus hookeri (C.B. Clarke) Hoeck which was widely used as traditional Tibetan medicine for treatment of rheumatoid arthritis. Their structures were determined by HR-ESI-MS, NMR analysis and CD experiment. The in vitro antiangiogenic effect of all isolated compounds against human umbilical vein endothelial cells (HUVECs) were evaluated by CCK-8 assay. Among them, compound 1 exhibited significant proliferative inhibition on HUVECs with IC50 value of 32.82 ± 0.99 μM. Further in vitro study indicated 1 could arrest cell cycle at G0/G1 phase and reduce the migration of HUVECs. In vivo experiment exhibited 1 could inhibit tail vessels plexus in zebrafish. The above finding suggested that 1 was a promising lead compound against RA by inhibiting of angiogenesis.

Zanthoxylum armatum, its peels possessed better special flavour, as well as various bioactivities, such as anti-inflammatory, anti-microbial and anti-tumour. In our chemical investigation on the peels of Z. armatum, two new lignans (1 and 2) and three known lignans (3–5) were isolated by silica gel column chromatography, ODS column and preparative HPLC and their structures were established as zanthlignans A and B (1–2), (-)-asarinin (3), phylligenin (4) and planispine A (5) through various spectroscopic techniques including UV, IR, HR-ESI-MS, NMR and CD methods.

Let G be a locally compact group and let 1 ≤ p < 1. Recently, Chen et al. characterized hypercyclic, supercyclic and chaotic weighted translations on locally compact groups and their homogeneous spaces. There has been an increasing interest in studying the disjoint hypercyclicity acting on various spaces of holomorphic functions. In this note, we will study disjoint hypercyclic and disjoint supercyclic powers of weighted translation operators on the Lebesgue space L p(G) in terms of the weights. Sufficient and necessary conditions for disjoint hypercyclic and disjoint supercyclic powers of weighted translations generated by aperiodic elements on groups will be given.

This paper deals with experimental study of flow field of starting process in two-dimensional, single-stage supersonic ejector on different air total pressure. Schlieren pictures of flow field were taken, static pressure distributions on side wall were measured. The obtained results show that, on critical pressure, the starting main shock waves in ejector oscillated back and forth between the second throat and the middle section of the mixing chamber, it causes the pressure in the second half of the mixing chamber acutely fluctuated.When the working pressure of the active flow is higher than the critical starting pressure, ejector starts normally and the inner flow-field of the mixing chamber keeps stable and the shock waves in the second throat have a certain degree of oscillation. After ejector starts, the operating pressure of the active flow may be lower than the starting pressure.