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The research is devoted to solving the problem of regulating the porosity parameters during the manufacturing process under magnetic field conditions. The process of synthesizing magnetic nanocomponents based on a mixture of divalent and trivalent iron oxides was given. The use of nanocomponents allowed for improving the conditions for creating porous materials. A device with adjustable magnetic induction was developed to produce porous materials in a magnetic field. The study of the porous material’s structure with the nanopowder content in the magnetic field conditions showed a clear dependence of the structure on the magnetic parameters. When the content of nanocomponents increased to 0.3 %, and the magnetic field induction increased to 2.5 mT, the dispersion of pore sizes decreased by 8–10 times, the density of pores – increased by 15–20 times, and the average diameter of pores – decreased by 12–15 times. Mathematical dependencies that determine the porosity parameters for different values of the magnetic nanopowder content and the level of magnetic induction in the ring electromagnet were proposed. The obtained dependencies allowed for assigning the level of magnetic technological parameters to ensure the given porosity parameters. The developed methods of magnetic technology for creating porous materials can increase the quality and ensure the required porosity level.

Females from many mosquito species feed on blood to acquire nutrients for egg development. The oogenetic cycle has been characterized in the arboviral vector Aedes aegypti, where after a bloodmeal, the lipid transporter lipophorin (Lp) shuttles lipids from the midgut and fat body to the ovaries, and a yolk precursor protein, vitellogenin (Vg), is deposited into the oocyte by receptor-mediated endocytosis. Our understanding of how the roles of these two nutrient transporters are mutually coordinated is however limited in this and other mosquito species. Here, we demonstrate that in the malaria mosquito Anopheles gambiae, Lp and Vg are reciprocally regulated in a timely manner to optimize egg development and ensure fertility. Defective lipid transport via Lp knockdown triggers abortive ovarian follicle development, leading to misregulation of Vg and aberrant yolk granules. Conversely, depletion of Vg causes an upregulation of Lp in the fat body in a manner that appears to be at least partially dependent on target of rapamycin (TOR) signaling, resulting in excess lipid accumulation in the developing follicles. Embryos deposited by Vg-depleted mothers are completely inviable, and are arrested early during development, likely due to severely reduced amino acid levels and protein synthesis. Our findings demonstrate that the mutual regulation of these two nutrient transporters is essential to safeguard fertility by ensuring correct nutrient balance in the developing oocyte, and validate Vg and Lp as two potential candidates for mosquito control., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2024 Stryapunina et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)