1. Genetic distance of SARS coronavirus from the recent natural case
- Author
-
Wang, Zhi-Gang, Xu, Shu-Ping, Zhang, Yan-Jun, and Bao, Qi-Yu
- Subjects
- *
EPIDEMICS , *SARS disease , *CORONAVIRUS diseases , *AMINO acid sequence - Abstract
Abstract: Phylogenetic analysis of SARS coronavirus isolates based on the spike gene and protein sequence using Neighbor-Joining, maximum likelihood and Bayesian inference methods indicated that a recent human SARS-CoV isolate was closer to some human SARS-CoV isolates from earlier epidemic phase than to the SARS-CoV-like viruses isolated from wild animals during previous epidemic phase. A reasonable judgment based on phylogenetic relationship and sequence variations it is likely that the recent human SARS-CoV isolate is closer to an unknown SARS-CoV predecessor. [Copyright &y& Elsevier]
- Published
- 2007
- Full Text
- View/download PDF