284 results on '"Humphreys, Ian R."'
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2. A pseudotyped adenovirus serotype 5 vector with serotype 49 fiber knob is an effective vector for vaccine and gene therapy applications
3. A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4+ T cell activation
4. Genetic manipulation of Patescibacteria provides mechanistic insights into microbial dark matter and the epibiotic lifestyle
5. Generalized biomolecular modeling and design with RoseTTAFold All-Atom
6. Essential and virulence-related protein interactions of pathogens revealed through deep learning
7. Genetic influences on viral-induced cytokine responses in the lung
8. Generalized Biomolecular Modeling and Design with RoseTTAFold All-Atom
9. COVID-19 and X-linked agammaglobulinemia (XLA) – insights from a monogenic antibody deficiency
10. Inhibitory IL-10-producing CD4+ T cells are T-bet-dependent and facilitate cytomegalovirus persistence via coexpression of arginase-1
11. Evolutionarily Divergent Herpesviruses Modulate T Cell Activation by Targeting the Herpesvirus Entry Mediator Cosignaling Pathway
12. Recent advances in predicting and modeling protein–protein interactions
13. Genetic manipulation of candidate phyla radiation bacteria provides functional insights into microbial dark matter
14. A longitudinal assessment of host-microbe-parasite interactions resolves the zebrafish gut microbiome’s link to Pseudocapillaria tomentosa infection and pathology
15. Acquisition of suppressive function by conventional T cells limits antitumor immunity upon Treg depletion.
16. Best practice for wildlife gut microbiome research: A comprehensive review of methodology for 16S rRNA gene investigations
17. A Targeted Amino Acid Mutation in Influenza a Virus Universal Epitope Transforms Immunogenicity and Protective Immunity via CD4 T Cell Activation
18. Inhibitory IL-10-producing CD4+ T cells are T-bet-dependent and facilitate cytomegalovirus persistence via coexpression of arginase-1.
19. NBEAL2 is required for neutrophil and NK cell function and pathogen defense
20. The antiviral restriction factor IFN-induced transmembrane protein 3 prevents cytokine-driven CMV pathogenesis
21. Novel viral vectors in infectious diseases
22. The Marine-Derived Macrolactone Mandelalide A Is an Indirect Activator of AMPK
23. SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies
24. Author response: SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies
25. An Analysis of Serological Response and Infection Outcomes Following Oxford-AstraZeneca (AZD1222) and Pfizer-BioNTech (mRNA BNT162b2) SARS-CoV-2 Vaccines in Kidney and Kidney-pancreas Transplants
26. Computed structures of core eukaryotic protein complexes
27. A Systematic Review and Meta-Analysis of Inpatient Mortality Associated With Nosocomial and Community COVID-19 Exposes the Vulnerability of Immunosuppressed Adults
28. IL-27 enhances MCMV chronicity by promoting the development of immune suppressive virus-specific IL-10+ CD4+ T-cells: ID: 200
29. IFITM3 restricts virus-induced pathogenesis by regulating myeloid cell production of interleukin-6: ID: 170
30. Structures of core eukaryotic protein complexes
31. 1524 Design and Implementation Of ICE-COVID, A Double-Blind Randomised Placebo-Controlled Trial on The Efficacy of Iota-Carrageenan Nasal and Throat Spray for Covid-19 Prophylaxis
32. Protein oligomer modeling guided by predicted interchain contacts in CASP14
33. Protein tertiary structure prediction and refinement using deep learning and Rosetta in CASP14
34. Burden of nosocomial COVID-19 in Wales: results from a multicentre retrospective observational study of 2508 hospitalised adults
35. Extended laboratory panel testing in the Emergency Department for risk-stratification of patients with COVID-19: a single centre retrospective service evaluation
36. Optimal CD8 + T‐cell memory formation following subcutaneous cytomegalovirus infection requires virus replication but not early dendritic cell responses
37. Interleukin-6 Signaling Drives Fibrosis in Unresolved Inflammation
38. Examining the utility of extended laboratory panel testing in the emergency department for risk stratification of patients with COVID-19: a single-centre retrospective service evaluation.
39. Examining the utility of extended laboratory panel testing in the emergency department for risk stratification of patients with COVID-19: a single-centre retrospective service evaluation
40. The burden of nosocomial covid-19: results from the Wales multi-centre retrospective observational study of 2518 hospitalised adults
41. IRF5 promotes influenza-induced inflammatory responses in human iPSC-derived myeloid cells and murine models
42. IFITM3‐specific antibody reveals IFN preferences and slow IFN induction of the antiviral factor IFITM3 in humans
43. Optimal CD8+ T-cell memory formation following subcutaneous cytomegalovirus infection requires virus replication but not early dendritic cell responses
44. Extended laboratory panel testing in the Emergency Department for risk-stratification of patients with COVID-19: a single centre retrospective service evaluation
45. Decision letter: Cytomegalovirus restricts ICOSL expression on antigen-presenting cells disabling T cell co-stimulation and contributing to immune evasion
46. Impaired Interleukin‐27–Mediated Control of CD 4+ T Cell Function Impact on Ectopic Lymphoid Structure Formation in Patients With Sjögren's Syndrome
47. Elevated interleukin‐6, interleukin‐10 and neutrophil : lymphocyte ratio as identifiers of severe coronavirus disease 2019
48. Interspecies comparative metagenomics reveals correlated gut microbiome functional capacities among vertebrates
49. An integrated gene catalog of the zebrafish gut microbiome reveals significant homology with mammalian microbiomes
50. A Critical Blimp-1-Dependent IL-10 Regulatory Pathway in T Cells Protects From a Lethal Pro-inflammatory Cytokine Storm During Acute Experimental Trypanosoma brucei Infection
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