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1. Momelotinib long-term safety and survival in myelofibrosis: integrated analysis of phase 3 randomized controlled trials

Author

Verstovsek, Srdan, Mesa, Ruben, Gupta, Vikas, Lavie, David, Dubruille, Viviane, Cambier, Nathalie, Platzbecker, Uwe, Hus, Marek, Xicoy, Blanca, Oh, Stephen T., Kiladjian, Jean-Jacques, Vannucchi, Alessandro M., Gerds, Aaron, Egyed, Miklos, Mayer, Jiří, Sacha, Tomasz, Kawashima, Jun, Morris, Marc, Huang, Mei, and Harrison, Claire

Published
2023
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2. Momelotinib versus danazol in symptomatic patients with anaemia and myelofibrosis (MOMENTUM): results from an international, double-blind, randomised, controlled, phase 3 study

Author

Abulafia, Adi Shacham, Al-Ali, Haifa Kathrin, Andreasson, Bjorn, Angona, Anna, Ayala, Rosa, Bang, Soo-Mee, Bank, Bruce, Barraco, Fiorenza, Beggiato, Eloise, Benghiat, Fleur Samantha, Bonifacio, MassimiliaNo, Bories, Claire, Borsaru, Gabriela, Brabrand, Mette, Braester, Andrei, Broliden, Andes, Buxhofer-Ausch, Veronika, Cambier, Nathalie, Caramella, Marianna, Carpentier, Benjamin, Cascavilla, Nicola, Castellano, Maria Giraldo, Chang, Hung, Chen, Chih-Cheng, Cheong, June-Won, Choi, Yunsuk, Choi, Philip, Corsetti, Maria Teresa, Cuadrado, Isabel Montero, Cunningham, Julia, Damaj, Gandhi Laurent, De Stefano, Valerio, Delage, Robert, Delgado, Regina Garcĺa, Diaz, Jose Miguel Torregrosa, Dombi, Péter, Dubruille, Viviane, Egyed, Miklós, El Fassi, Daniel, Elinder-Camburn, Anna, Elli, Elena Maria, Ellis, Martin, Fava, Carmen, Fazal, Salman, Fleischman, Angela, Foltz, Lynda, Fox, Laura, Gabrail, Nashat, Garcĺa-Gutiérrez, Jose Valentĺn, Gerds, Aaron, Girault, Stephane, Gisslinger, Heinz, Gluvacov, Alexandru, Goh, Yeow Tee, Göthert, Joachim, Granacher, Nikki, Grosicki, Sebastian, Gupta, Vikas, Hadjiev (Hadzhiev), Evgeni (Evgueniy), Hafraoui, Kaoutar, Hamed, Aryan, Harrison, Claire, Hasselbalch, Hans, Hauser, Hanns, Heaney, Mark, Hebart, Holger, Hernandez Rivas, Jesus Maria, Higuero Saavedra, Victor, Hillis, Christopher, Hou, Hsin-An, How, Jonathan, Huang, Daniel, Hus, Marek, Illés, Arpad, Isidori, Alessandro, Iurlo, Alessandra, Ivanov, Vadim, Johansson, Peter, Jung, Chul Won, Kiladjian, Jean-Jacques, Kirgner, Ilya, Koren-Michowitz, Maya, Koschmieder, Steffen, Kosztolanyi, Szabolcs Ors, Kreiniz, Natalia, Kuykendall, Andrew, Lambert, Jonathan, Laribi, Kamel, Lascaux, Axelle, Lavie, Noa, Lavie, David, Lazaroiu, Mihaela, Leahy, Michael, Lech-Maranda, Ewa, Lee, Sung-Eun, Lee, Won Sik, Legrand, Ollivier, Lemoli, Roberto, Liang, James, Lim, Sung-Nam, Loschi, Michael, Lucchesi, Alessandro, Macarie, Ioan, Marolleau, Jean-Pierre, Martelli, Maurizio, Mayer, Jiri, McCloskey, James, McDermott, Christopher, McLornan, Donal, McMahon, Brandon, Mehta, Priyanka, Mesa, Ruben, Mikala, Gábor, Milojkovic, Dragana, Mineur, Philippe, Mishchenko, Elena, Moon, Joon Ho, Nagy, Zsolt, Narayanan, Srinivasan, O'Connell, Casey, Ocroteala, Luminita, Oh, Stephen, Ojeda-Uribe, Mario, Ong, Kiat Hoe, Otegbeye, Folashade, Palmer, Jeanne, Pane, Fabrizio, Passamonti, Francesco, Patriarca, Andrea, Perkins, Andrew, Pietrantuono, Giuseppe, Plander, Mark, Platzbecker, Uwe, Prasad, Ritam, Prejzner, Witold, Rachow, Tobias, Radinoff, Atanas, Rejtő, László, Rinaldi, Ciro, Robak, Tadeusz, Rodriguez, Maria Angeles Fernandez, Ronson, Aaron, Ross, David, Sacha, Tomasz, Sadjadian, Parvis, Salar, Antonio, Santillana, Guillermo Sanz, Scheid, Christof, Schmidt, Aline, Severinsen, Marianne Tang, Stoeva, Vera, Szwedyk, Paweł, Tiribelli, Mario, Trautmann-Grill, Karolin, Trottier, Amy, Tzvetkov, Nikolay, van Droogenbroeck, Janusz, Vannucchi, Alessandro, Verstovsek, Srdan, Vianelli, Nicola, von Bubnoff, Nikolas, Wolf, Dominik, Woszczyk, Dariusz, Woźny, Tomasz, Wróbel, Tomasz, Xicoy, Blanca, Yeh, Su-Peng, Yoon, Sung-Soo, Gerds, Aaron T, Vannucchi, Alessandro M, Kuykendall, Andrew T, Lazaroiu, Mihaela C, Egyed, Miklos, Fox, Maria Laura, Harrison, Claire N, Klencke, Barbara J, Ro, Sunhee, Donahue, Rafe, and Kawashima, Jun

Published
2023
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3. Analysis of Predictive Factors for Early Response to Ruxolitinib in 320 Patients with Myelofibrosis From the Polish Adult Leukemia Group (PALG) Registry

Author

Góra-Tybor, Joanna, Gołos, Aleksandra, Mikulski, Damian, Helbig, Grzegorz, Sacha, Tomasz, Lewandowski, Krzysztof, Niesiobędzka-Krężel, Joanna, Bieniaszewska, Maria, Wysogląd, Hubert, Grzybowska-Izydorczyk, Olga, Seferyńska, Ilona, Sobas, Marta, Czyżewska, Maria, Michalska, Agnieszka, Sawicki, Waldemar, Mazur, Malwina, Hus, Marek, Bodzenta, Ewa, Olszewska-Szopa, Magdalena, Włodarczyk, Martyna, Patkowska, Elżbieta, Świstek, Wojciech, and Jamroziak, Krzysztof

Published
2023
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5. Patient-reported outcomes (PROs) from the DREAMM-7 randomized phase 3 study comparing belantamab mafodotin, bortezomib, and dexamethasone (BVd) vs daratumumab, bortezomib, and dexamethasone (DVd) in patients with relapsed/refractory multiple myeloma (RRMM).

Author

Hungria, Vania, primary, Robak, Pawel, additional, Hus, Marek, additional, Fu, Chengcheng, additional, Zherebtsova, Vera, additional, Ward, Christopher, additional, de Almeida, Ana Carolina, additional, Ho, P. Joy, additional, Hajek, Roman, additional, Cerchione, Claudio, additional, Pirooz, Nicholas, additional, McKeown, Astrid, additional, Baig, Hena, additional, Eccersley, Lydia, additional, Pompilus, Farrah, additional, McNamara, Simon, additional, Lin, Chee Paul, additional, Roy-Ghanta, Sumita, additional, Opalinska, Joanna, additional, and Mateos, Maria-Victoria, additional

Published
2024
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7. Phase 3 randomized COMMODORE 1 trial: Crovalimab versus eculizumab in complement inhibitor‐experienced patients with paroxysmal nocturnal hemoglobinuria.

Author

Scheinberg, Phillip, Clé, Diego Villa, Kim, Jin Seok, Nur, Erfan, Yenerel, Mustafa N., Barcellini, Wilma, Bonito, Debora, Giai, Valentina, Hus, Marek, Lee, YooJin, Lekue, Cristina Barrenetxea, Panse, Jens, Ueda, Yasutaka, Buatois, Simon, Gentile, Brittany, Kiialainen, Anna, Patel, Himika, Sreckovic, Sasha, Uguen, Marianne, and Edwards, John

Published
2024
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8. Stem Cell Mobilization Performed with Different Doses of Cytarabine in Plasma Cell Myeloma Patients Relapsing after Previous Autologous Hematopoietic Cell Transplantation—A Multicenter Report by the Polish Myeloma Study Group.

Author

Drozd-Sokołowska, Joanna, Waszczuk-Gajda, Anna, Topczewska, Magdalena, Maciejewska, Martyna, Dutka, Magdalena, Zaucha, Jan Maciej, Szmigielska-Kapłon, Anna, Nowicki, Mateusz, Olszewska-Szopa, Magdalena, Szeremet, Agnieszka, Czyż, Anna, Kozioł, Magdalena, Hus, Marek, Mańko, Joanna, Hus, Iwona, Romejko-Jarosińska, Joanna, Kopińska, Anna, Helbig, Grzegorz, Mądry, Krzysztof, and Boguradzki, Piotr

Subjects
MULTIPLE myeloma treatment, HEMATOPOIETIC stem cell transplantation, CANCER relapse, SALVAGE therapy, ORGAN donation, CYTARABINE, SEPTIC shock, DRUG efficacy, RESEARCH, COLLECTION & preservation of biological specimens, HEMATOPOIETIC stem cells, DISEASE risk factors
Abstract

Simple Summary: Autologous hematopoietic cell transplantation (auto-HCT) can be used to salvage at least a proportion of plasma cell myeloma patients who relapse after a previous auto-HCT. It may, however, occur that there is either no or an insufficient stem cell dose in storage to proceed to transplantation. Remobilization to procure new cells is then required. There are very limited data in the literature concerning the efficacy of stem cell remobilization after previous auto-HCT. In our previous report, we showed that remobilization with cytarabine was associated with a lower risk of remobilization failure in comparison to etoposide or cyclophosphamide. In the current study, we analyze the efficacy and safety of different doses of cytarabine (800, 1600, and 2400 mg/m2), showing that all doses are efficacious but that the dose of 2400 mg/m2 is associated with the most toxicity. Therefore, lower doses of cytarabine seem to be preferable, with plerixafor rescue when needed. Salvage autologous hematopoietic cell transplantation (auto-HCT) may be used to treat relapse of plasma cell myeloma occurring after previous auto-HCT. When an insufficient number of hematopoietic stem cells have been stored from the initial harvest, remobilization is necessary. Here, we aimed to analyze the efficacy and safety of different doses of cytarabine (total 800 vs. 1600 vs. 2400 mg/m2) for remobilization. Sixty-five patients, 55% male, with a median age at remobilization 63 years, were included. Remobilization was performed with cytarabine_800 in 7, cytarabine_1600 in 36, and cytarabine_2400 in 22 patients. Plerixafor rescue was used in 25% of patients receiving cytarabine_1600 and 27% of those receiving cytarabine_2400. Patients administered cytarabine_800 were not rescued with plerixafor. Remobilization was successful in 80% of patients (57% cytarabine_800; 86% cytarabine_1600; 77% cytarabine_2400; p = 0.199). The yield of collected CD34+ cells did not differ between the different cytarabine doses (p = 0.495). Patients receiving cytarabine_2400 were at the highest risk of developing severe cytopenias, requiring blood product support, or having blood-stream infections. One patient died of septic shock after cytarabine_2400. In summary, remobilization with cytarabine is feasible in most patients. All doses of cytarabine allow for successful remobilization. Cytarabine_2400 is associated with higher toxicity; therefore, lower doses (800 or 1600 mg/m2) seem to be preferable. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Results from the randomized phase III DREAMM-7 study of belantamab mafodotin (belamaf) + bortezomib, and dexamethasone (BVd) vs daratumumab, bortezomib, and dexamethasone (DVd) in relapsed/refractory multiple myeloma (RRMM).

Author

Mateos, Maria-Victoria, primary, Robak, Pawel, additional, Hus, Marek, additional, Xia, Zhongjun, additional, Zherebtsova, Vera, additional, Ward, Christopher, additional, Ho, P. Joy, additional, Hajek, Roman, additional, Kim, Kihyun, additional, Dimopoulos, Meletios A., additional, Cerchione, Claudio, additional, Riccio, Antonio, additional, McKeown, Astrid, additional, Rogers, Rachel, additional, Baig, Hena, additional, Eccersley, Lydia, additional, Roy-Ghanta, Sumita, additional, Opalinska, Joanna, additional, and Hungria, Vania, additional

Published
2024
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13. Predicting chemotherapy toxicity in multiple myeloma: the prognostic value of pretreatment serum cytokine levels of interleukin-6, interleukin-8, monocyte chemoattractant protein-1, and vascular endothelial growth factor.

Author

Mielnik, Michał, Podgajna-Mielnik, Martyna, Szudy-Szczyrek, Aneta, Homa-Mlak, Iwona, Mlak, Radosław, Gorący, Aneta, and Hus, Marek

Subjects
VASCULAR endothelial growth factors, PROGNOSIS, LYMPHOPENIA, MULTIPLE myeloma, INTERLEUKIN-8, INTERLEUKIN-6
Abstract

Introduction: Multiple Myeloma (MM), a prevalent hematological malignancy, poses significant treatment challenges due to varied patient responses and toxicities to chemotherapy. This study investigates the predictive value of pretreatment serum levels of interleukin-6 (IL-6), interleukin-8 (IL-8), monocyte chemoattractant protein-1 (MCP-1), and vascular endothelial growth factor (VEGF) for chemotherapy-induced toxicities in newly diagnosed MM patients. We hypothesized that these cytokines, pivotal in the tumor microenvironment, might correlate with the incidence and severity of treatment-related adverse events. Methods: We conducted a prospective observational study with 81 newly diagnosed MM patients, analyzing serum cytokine levels using the multiplex cytometric bead assay (CBA) flow cytometry method. The study used nonparametric and multivariate analysis to compare cytokine levels with treatment-induced toxicities, including lymphopenia, infections, polyneuropathy, and neutropenia. Results: Our findings revealed significant associations between cytokine levels and specific toxicities. IL-8 levels were lower in patients with lymphopenia (p=0.0454) and higher in patients with infections (p=0.0009) or polyneuropathy (p=0.0333). VEGF concentrations were notably lower in patients with neutropenia (p=0.0343). IL-8 demonstrated an 81% sensitivity (AUC=0.69; p=0.0015) in identifying infection risk. IL-8 was an independent predictor of lymphopenia (Odds Ratio [OR]=0.26; 95% Confidence Interval [CI] =0.07-0.78; p=0.0167) and infection (OR=4.76; 95% CI=0.07-0.62; p=0.0049). High VEGF levels correlated with a 4-fold increased risk of anemia (OR=4.13; p=0.0414). Conclusions: Pre-treatment concentrations of IL-8 and VEGF in serum can predict hematological complications, infections, and polyneuropathy in patients with newly diagnosed MM undergoing chemotherapy. They may serve as simple yet effective biomarkers for detecting infections, lymphopenia, neutropenia, and treatment-related polyneuropathy, aiding in the personalization of chemotherapy regimens and the mitigation of treatment-related risks. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Efficacy of high-dose corticosteroid-based treatment for chronic lymphocytic leukemia patients with p53 abnormalities in the era of B-cell receptor inhibitors

Author

Puła, Bartosz, Długosz-Danecka, Monika, Salomon-Perzyński, Aleksander, Szymczyk, Agnieszka, Subocz, Edyta, Budziszewska, Bożena Katarzyna, Rybka, Justyna, Gil, Lidia, Waszczuk-Gajda, Anna, Iskierka-Jażdżewska, Elżbieta, Zaucha, Jan M., Osowiecki, Michał, Piszczek, Weronika, Steckiewicz, Paweł, Szukalski, Łukasz, Hus, Marek, Lech-Marańda, Ewa, Jurczak, Wojciech, and Jamroziak, Krzysztof

Published
2020
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17. Pomalidomide, bortezomib, and dexamethasone for patients with relapsed or refractory multiple myeloma previously treated with lenalidomide (OPTIMISMM): a randomised, open-label, phase 3 trial

Author

Abildgaard, Niels, Adler, Howard, Altuntas, Fevzi, Akay, Olga Meltem, Amin, Bipinkumar, Anagnostopoulos, Achilleas, Anderson, Larry, Anttila, Pekka, Araujo, Carla, Arce-Lara, Carlos, Aydin, Yildiz, Basu, Supratik, Battini, Ramakrishna, Beeker, Thaddeus, Benboubker, Lotfi, Ben-Yehuda, Dina, Bladé, Joan, Blau, Igor Wolfgang, Boccia, Ralph, Burke, Lillian, Byeff, Peter, Cascavilla, Nicola, Cavo, Michele, Chantry, Andrew, Charles, Yen, Chaudhry, Arvind, Corso, Alessandro, Coyne, Mark, De Arriba, Felipe, Delimpasi, Sosana, Desjardins, Pierre, Dhakal, Binod, Di Bartolomeo, Paolo, Di Raimondo, Francesco, Dürig, Jan, Engelhardt, Monika, Escoffre-Barbe, Martine, Esteves, Graca, Flogegard, Max, Gabrail, Nashat, Gamberi, Barbara, Garrison, Mitchell, Gay, Julie, Gisslinger, Heinz, Goldschmidt, Hartmut, Goncalves, Cristina, Gressot, Laurent, Grosicki, Sebastian, Hanna, Wahid, Hayden, Patrick, Henriques Bernardo, Maria Manuela, Hermann, Robert, Holden, Viran, Honkalehto, Kirsti, Huben, Marianne, Huffman, John, Hunter, Hannah, Hus, Marek, Jagasia, Madan, Jagganath, Sundar, Janakiram, Murali, Jaiyesimi, Ishmael, Jenner, Matthew, João, Cristina, Johnson, Peter, Jurcyszyn, Artur, Kalayoğlu Beşişik, Sevgi, Kambhampati, Suman, Kanate, Abraham, Karadoğan, Ihsan, Khojasteh, Ali, Kirkel, Dean, Komarnicki, Mieczyslaw, Krauth, Maria-Theresa, Kuriakose, Phillip, Larocca, Alessandra, Lauri, Birgitta, Leleu, Xavier, Lucio, Paulo, Luppi, Mario, Mangiacavalli, Silvia, Mariette, Clara, Matsue, Kosei, Mellqvist, Ulf-Henri, Mendeleeva, Larisa, Meshad, Michael, Miller, Carole, Mohrbacher, Ann, Moreau, Philippe, Morelli, Anna Maria, Müldür, Ercan, Naassan, Anthony, Nahi, Hareth, Nair, Rajesh, O'Dwyer, Mike, Öngören Aydin, Seniz, Openshaw, Thomas, O'Rourke, Timothy, Osswald, Michael, Overton, Lindsay, Pati, Asmin, Pavic, Michel, Pegourie, Brigitte, Pehlivan, Mustafa, Pierola, Ana Alfonso, Plesner, Torben, Pluta, Andrzej, Rabin, Neil, Ramasamy, Karthik, Rambaldi, Alessandro, Rodriguez, Paula, Röllig, Christoph, Rosenblatt, Jacalyn, Rosenbluth, Jonathan, Salomo, Morten, Samoylova, Olga, Sastre Moral, Jose, Sati, Hamdi, Selleri, Carmine, Shafeek, Salim, Shinagawa, Atsushi, Sleckman, Bethany, Smith, Clay, Sonmez, Mehmet, Stone, Chester, Streetly, Matthew, Suzuki, Kenshi, Taetle, Raymond, Tafuri, Agostino, Takezako, Naoki, Teke, Hava Üsküdar, Vapaatalo, Mirja, Vassilopoulos, George, Verma, Amit, Vidito, Sarah, Viterbo, Luisa, Vural, Filiz, Wang, Xiang Sean, Yağci, Munci, Yee, Andrew, Richardson, Paul G, Oriol, Albert, Beksac, Meral, Liberati, Anna Marina, Galli, Monica, Schjesvold, Fredrik, Lindsay, Jindriska, Weisel, Katja, White, Darrell, Facon, Thierry, San Miguel, Jesus, Sunami, Kazutaka, O'Gorman, Peter, Sonneveld, Pieter, Robak, Pawel, Semochkin, Sergey, Schey, Steve, Yu, Xin, Doerr, Thomas, Bensmaine, Amine, Biyukov, Tsvetan, Peluso, Teresa, Zaki, Mohamed, Anderson, Kenneth, and Dimopoulos, Meletios

Published
2019
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18. MM-533 Low-Dose Belantamab Mafodotin (Belamaf) in Combination With Nirogacestat Versus Belamaf Monotherapy in Patients With Relapsed/Refractory Multiple Myeloma (RRMM): Phase 1/2 DREAMM-5 Platform Sub-Study 3

Author

Callander, Natalie S., primary, Richardson, Paul G., additional, Hus, Marek, additional, Ribrag, Vincent, additional, Lopez, Joaquin Martinez, additional, Kim, Kihyun, additional, Lee, Jae Hoon, additional, Dimopoulos, Meletis, additional, Schjesvold, Fredrik, additional, Facon, Thierry, additional, Jo, Jae-Cheol, additional, Min, Chang-Ki, additional, Mielnik, Michał, additional, Cheng, Shinta, additional, Smith, L. Mary, additional, Breitbach, Caroline J., additional, Brawley, Chris, additional, Sembhi, Harjeet, additional, LaMacchia, John, additional, Hakim, Shawn, additional, Kremer, Brandon E., additional, and Grosicki, Sebastian, additional

Published
2023
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19. POSTER: MM-533 Low-Dose Belantamab Mafodotin (Belamaf) in Combination With Nirogacestat Versus Belamaf Monotherapy in Patients With Relapsed/Refractory Multiple Myeloma (RRMM): Phase 1/2 DREAMM-5 Platform Sub-Study 3

Author

Callander, Natalie S., primary, Richardson, Paul G., additional, Hus, Marek, additional, Ribrag, Vincent, additional, Lopez, Joaquin Martinez, additional, Kim, Kihyun, additional, Lee, Jae Hoon, additional, Dimopoulos, Meletis, additional, Schjesvold, Fredrik, additional, Facon, Thierry, additional, Jo, Jae-Cheol, additional, Min, Chang-Ki, additional, Mielnik, Michał, additional, Cheng, Shinta, additional, Smith, L. Mary, additional, Breitbach, Caroline J., additional, Brawley, Chris, additional, Sembhi, Harjeet, additional, LaMacchia, John, additional, Hakim, Shawn, additional, Kremer, Brandon E., additional, and Grosicki, Sebastian, additional

Published
2023
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21. S183: PHASE III RANDOMIZED, MULTICENTER, OPEN-LABEL COMMODORE 1 TRIAL: COMPARISON OF CROVALIMAB VS ECULIZUMAB IN COMPLEMENT INHIBITOR-EXPERIENCED PATIENTS WITH PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH)

Author

Scheinberg, Phillip, primary, Cle, Diego, additional, Edwards, John, additional, Giai, Valentina, additional, Hus, Marek, additional, Kim, Jin Seok, additional, Lekue, Cristina Barrenetxea, additional, Nagy, Zsolt, additional, Nur, Erfan, additional, Panse, Jens, additional, Ueda, Yasutaka, additional, Yenerel, Mustafa Nuri, additional, Appius, Anita, additional, Balachandran, Nadiesh, additional, Chebon, Sammy, additional, Gentile, Brittany, additional, Buatois, Simon, additional, and Kulasekararaj, Austin, additional

Published
2023
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22. P491: DAY 14 MEASURABLE RESIDUAL DISEASE ASSESSMENT PREDICTS TREATMENT OUTCOMES IN PATIENTS WITH ACUTE MYELOID LEUKEMIA TREATED WITH INTENSIVE CHEMOTHERAPY - RESULTS OF THE PALG-AML1/2016 STUDY

Author

Wierzbowska, Agnieszka, primary, Pluta, Agnieszka, additional, Czyz, Anna, additional, Czemerska, Magdalena, additional, Mikulski, Damian, additional, Stelmach, Piotr, additional, Libura, Marta, additional, Giebel, Sebastian, additional, Kopinska, Agnieszka, additional, Wozniczka, Krzysztof, additional, Helbig, Grzegorz, additional, Wojcik, Karol, additional, Razny, Malgorzata, additional, Sobas, Marta, additional, Wróbel, Tomasz, additional, Szczepaniak, Andrzej, additional, Gil, Lidia, additional, Dutka, Magdalena, additional, Bieniaszewska, Maria, additional, Maciej Zaucha, Jan, additional, Gromek, Tomasz, additional, Hus, Marek, additional, Cichocka, Edyta, additional, Halka, Janusz, additional, Patkowska, Elzbieta, additional, Wozniak, Jolanta, additional, Obara, Agata, additional, Kopacz, Agnieszka, additional, Dulik, Katarzyna, additional, Holowiecki, Jerzy, additional, Soin, Michał, additional, Fendler, Wojciech, additional, Rustani, Andi, additional, Kaner, Justin, additional, Mencia-Trinchant, Nuria, additional, Desai, Pinkal, additional, Lee, Sangmin, additional, Samuel, Michael, additional, Ritchie, Ellen, additional, Guzman, Monica, additional, and Roboz, Gail, additional

Published
2023
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23. P913: LOW-DOSE BELANTAMAB MAFODOTIN (BELAMAF) IN COMBINATION WITH NIROGACESTAT VS BELAMAF MONOTHERAPY IN PATIENTS WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA (RRMM): PHASE 1/2 DREAMM-5 PLATFORM SUB-STUDY 3

Author

Callander, Natalie, primary, Richardson, Paul, additional, Hus, Marek, additional, Ribrag, Vincent, additional, Martinez-Lopez, Joaquín, additional, Kim, Kihyun, additional, Hoon Lee, Jae, additional, Dimopoulos, Meletios A., additional, Schjesvold, Fredrik, additional, Facon, Thierry, additional, Jo, Jae-Cheol, additional, Min, Chang-Ki, additional, Mielnik, Michał, additional, Cheng, Shinta, additional, Smith, Mary, additional, Breitbach, Caroline J., additional, Brawley, Chris, additional, Sembhi, Harjeet, additional, Lamacchia, John, additional, and Grosicki, Sebastian, additional

Published
2023
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24. P864: A PHASE 1 STUDY OF BELANTAMAB MAFODOTIN IN COMBINATION WITH STANDARD OF CARE IN NEWLY DIAGNOSED MULTIPLE MYELOMA: AN INTERIM ANALYSIS OF DREAMM-9

Author

Usmani, Saad Z, primary, Mielnik, Michał, additional, Min Byun, Ja, additional, Alonso Alonso, Aránzazu, additional, Abdallah, Al-Ola, additional, Garg, Mamta, additional, Quach, Hang, additional, Min, Chang-Ki, additional, Janowski, Wojciech, additional, Miguel, Enrique Maria Ocio San, additional, Weisel, Katja, additional, Oriol, Albert, additional, Sandhu, Irwindeep, additional, Rodríguez-Otero, Paula, additional, Ramasamy, Karthik, additional, Egger, Jacqueline, additional, Williams, Danaè, additional, MA, Jie, additional, Kaisermann, Morrys, additional, and Hus, Marek, additional

Published
2023
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26. Age-dependent determinants of infectious complications profile in children and adults after hematopoietic cell transplantation: lesson from the nationwide study

Author

Czyżewski, Krzysztof, Styczyński, Jan, Giebel, Sebastian, Frączkiewicz, Jowita, Salamonowicz, Małgorzata, Zając-Spychala, Olga, Zaucha-Prażmo, Agnieszka, Drozd-Sokołowska, Joanna, Waszczuk-Gajda, Anna, Dybko, Jarosław, Mańko, Joanna, Zalas-Więcek, Patrycja, Gałązka, Przemysław, Wysocki, Mariusz, Kowalczyk, Jerzy, Wachowiak, Jacek, Goździk, Jolanta, Basak, Grzegorz W, Kałwak, Krzysztof, Adamska, Monika, Hus, Marek, Piekarska, Agnieszka, Sadowska-Klasa, Alicja, Mensah-Glanowska, Patrycja, Kyrcz-Krzemień, Sławomira, Biernat, Monika, Wierzbowska, Agnieszka, Rzepecki, Piotr, Tomaszewska, Agnieszka, Hałaburda, Kazimierz, Gil, Lidia, and for Polish Society of Pediatric Oncology and Hematology and Polish Society of Hematology and Blood Transfusion

Published
2019
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28. Analiza skuteczności ibrutynibu w podgrupie chorych na przewlekłą białaczkę limfocytową z delecją 17p: badanie obserwacyjne Polskiej Grupy ds. Leczenia Białaczek u Dorosłych (PALG)

Author

Puła, Bartosz, Iskierka-Jażdżewska, Elżbieta, Hus, Marek, Szymczyk, Agnieszka, Gołos, Aleksandra, Piotrowska, Magdalena, Zawirska, Daria, Zaucha, Jan Maciej, Steckiewicz, Paweł, Pasiarski, Marcin, Chraniuk, Dominik, Piszczek, Weronika, Osowiecki, Michał, Subocz, Edyta, Hałka, Janusz, Waszczuk-Gajda, Anna, Drozd-Sokołowska, Joanna, Knopińska-Posłuszny, Wanda, Dudziński, Marek, Hołojda, Jadwiga, Wojciechowska, Małgorzata, Kulikowski, Waldemar, Szeremet, Agnieszka, Kumiega, Beata, Pluta, Andrzej, Markiewicz, Mirosław, Giannopoulos, Krzysztof, Robak, Tadeusz, Warzocha, Krzysztof, and Jamroziak, Krzysztof

Published
2017
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29. A phase 1 study of belantamab mafodotin in combination with standard of care in newly diagnosed multiple myeloma: An interim analysis of DREAMM-9.

Author

Usmani, Saad Zafar, primary, Mielnik, Michał, additional, Byun, Ja Min, additional, Alonso, Aránzazu Alonso, additional, Abdallah, Al-Ola A., additional, Garg, Mamta, additional, Quach, Hang, additional, Min, Chang-Ki, additional, Janowski, Wojciech, additional, Ocio, Enrique M., additional, Weisel, Katja, additional, Oriol, Albert, additional, Sandhu, Irwindeep, additional, Rodríguez-Otero, Paula, additional, Ramasamy, Karthik, additional, Egger, Jacqueline L., additional, Williams, Danae, additional, Ma, Jie, additional, Kaisermann, Morrys C., additional, and Hus, Marek, additional

Published
2023
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30. SARS-CoV-2 infection in patients with multiple myeloma: survey in 23 centers across Europe and USA

Author

Dytfeld, Dominik, primary, Radocha, Jakub, additional, Hajek, Roman, additional, Cengiz-Seval, Guldane, additional, Berkac, Meral, additional, Coriu, Daniel, additional, Derman, Benjamin, additional, Jakubowiak, Andrzej, additional, Peceliunas, Valdas, additional, Mikkala, Gabor, additional, Bołkun, Łukasz, additional, Hawrylecka, Dorota, additional, Grosicki, Sebastian, additional, Tyczyńska, Agata, additional, Zaucha, Jan Maciej, additional, Knopińska, Wanda, additional, Semeńczuk, Grażyna, additional, Morawska, Marta, additional, Giannopoulos, Krzysztof, additional, Puła, Anna, additional, Rymko, Marcin, additional, Charliński, Grzegorz, additional, Szeremet, Agnieszka, additional, Kalicińska, Elżbieta, additional, Usnarska, Lidia, additional, Wróbel, Tomasz, additional, Jamroziak, Krzysztof, additional, Druzd-Sitek, Agnieszka, additional, Romejko Jarosińska, Joanna, additional, Sawicki, Waldemar, additional, Waszczuk-Gajda, Anna, additional, Juda, Adrian, additional, Hus, Marek, additional, and Gil, Lidia, additional

Published
2023
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31. The TT Genotype of the KIAA1524 rs2278911 Polymorphism Is Associated with Poor Prognosis in Multiple Myeloma

Author

Szudy-Szczyrek, Aneta, primary, Mlak, Radosław, additional, Mazurek, Marcin, additional, Krajka, Tomasz, additional, Chocholska, Sylwia, additional, Bitkowska, Paulina, additional, Jutrzenka, Marta, additional, Szczyrek, Michał, additional, Homa-Mlak, Iwona, additional, Krajka, Andrzej, additional, Małecka-Massalska, Teresa, additional, and Hus, Marek, additional

Published
2023
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32. Comparison of SOX2 and POU5F1 Gene Expression in Leukapheresis-Derived CD34+ Cells before and during Cell Culture

Author

Świstowska, Małgorzata, primary, Gil-Kulik, Paulina, additional, Czop, Marcin, additional, Wieczorek, Katarzyna, additional, Macheta, Arkadiusz, additional, Petniak, Alicja, additional, Cioch, Maria, additional, Hus, Marek, additional, Szuta, Mariusz, additional, Rahnama-Hezavah, Mansur, additional, Płachno, Bartosz J., additional, and Kocki, Janusz, additional

Published
2023
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34. Momelotinib versus danazol in symptomatic patients with anaemia and myelofibrosis (MOMENTUM): results from an international, double-blind, randomised, controlled, phase 3 study

Author

Verstovsek, Srdan, primary, Gerds, Aaron T, additional, Vannucchi, Alessandro M, additional, Al-Ali, Haifa Kathrin, additional, Lavie, David, additional, Kuykendall, Andrew T, additional, Grosicki, Sebastian, additional, Iurlo, Alessandra, additional, Goh, Yeow Tee, additional, Lazaroiu, Mihaela C, additional, Egyed, Miklos, additional, Fox, Maria Laura, additional, McLornan, Donal, additional, Perkins, Andrew, additional, Yoon, Sung-Soo, additional, Gupta, Vikas, additional, Kiladjian, Jean-Jacques, additional, Granacher, Nikki, additional, Lee, Sung-Eun, additional, Ocroteala, Luminita, additional, Passamonti, Francesco, additional, Harrison, Claire N, additional, Klencke, Barbara J, additional, Ro, Sunhee, additional, Donahue, Rafe, additional, Kawashima, Jun, additional, Mesa, Ruben, additional, Abulafia, Adi Shacham, additional, Andreasson, Bjorn, additional, Angona, Anna, additional, Ayala, Rosa, additional, Bang, Soo-Mee, additional, Bank, Bruce, additional, Barraco, Fiorenza, additional, Beggiato, Eloise, additional, Benghiat, Fleur Samantha, additional, Bonifacio, MassimiliaNo, additional, Bories, Claire, additional, Borsaru, Gabriela, additional, Brabrand, Mette, additional, Braester, Andrei, additional, Broliden, Andes, additional, Buxhofer-Ausch, Veronika, additional, Cambier, Nathalie, additional, Caramella, Marianna, additional, Carpentier, Benjamin, additional, Cascavilla, Nicola, additional, Castellano, Maria Giraldo, additional, Chang, Hung, additional, Chen, Chih-Cheng, additional, Cheong, June-Won, additional, Choi, Yunsuk, additional, Choi, Philip, additional, Corsetti, Maria Teresa, additional, Cuadrado, Isabel Montero, additional, Cunningham, Julia, additional, Damaj, Gandhi Laurent, additional, De Stefano, Valerio, additional, Delage, Robert, additional, Delgado, Regina Garcĺa, additional, Diaz, Jose Miguel Torregrosa, additional, Dombi, Péter, additional, Dubruille, Viviane, additional, Egyed, Miklós, additional, El Fassi, Daniel, additional, Elinder-Camburn, Anna, additional, Elli, Elena Maria, additional, Ellis, Martin, additional, Fava, Carmen, additional, Fazal, Salman, additional, Fleischman, Angela, additional, Foltz, Lynda, additional, Fox, Laura, additional, Gabrail, Nashat, additional, Garcĺa-Gutiérrez, Jose Valentĺn, additional, Gerds, Aaron, additional, Girault, Stephane, additional, Gisslinger, Heinz, additional, Gluvacov, Alexandru, additional, Göthert, Joachim, additional, Hadjiev (Hadzhiev), Evgeni (Evgueniy), additional, Hafraoui, Kaoutar, additional, Hamed, Aryan, additional, Harrison, Claire, additional, Hasselbalch, Hans, additional, Hauser, Hanns, additional, Heaney, Mark, additional, Hebart, Holger, additional, Hernandez Rivas, Jesus Maria, additional, Higuero Saavedra, Victor, additional, Hillis, Christopher, additional, Hou, Hsin-An, additional, How, Jonathan, additional, Huang, Daniel, additional, Hus, Marek, additional, Illés, Arpad, additional, Isidori, Alessandro, additional, Ivanov, Vadim, additional, Johansson, Peter, additional, Jung, Chul Won, additional, Kirgner, Ilya, additional, Koren-Michowitz, Maya, additional, Koschmieder, Steffen, additional, Kosztolanyi, Szabolcs Ors, additional, Kreiniz, Natalia, additional, Kuykendall, Andrew, additional, Lambert, Jonathan, additional, Laribi, Kamel, additional, Lascaux, Axelle, additional, Lavie, Noa, additional, Lazaroiu, Mihaela, additional, Leahy, Michael, additional, Lech-Maranda, Ewa, additional, Lee, Won Sik, additional, Legrand, Ollivier, additional, Lemoli, Roberto, additional, Liang, James, additional, Lim, Sung-Nam, additional, Loschi, Michael, additional, Lucchesi, Alessandro, additional, Macarie, Ioan, additional, Marolleau, Jean-Pierre, additional, Martelli, Maurizio, additional, Mayer, Jiri, additional, McCloskey, James, additional, McDermott, Christopher, additional, McMahon, Brandon, additional, Mehta, Priyanka, additional, Mikala, Gábor, additional, Milojkovic, Dragana, additional, Mineur, Philippe, additional, Mishchenko, Elena, additional, Moon, Joon Ho, additional, Nagy, Zsolt, additional, Narayanan, Srinivasan, additional, O'Connell, Casey, additional, Oh, Stephen, additional, Ojeda-Uribe, Mario, additional, Ong, Kiat Hoe, additional, Otegbeye, Folashade, additional, Palmer, Jeanne, additional, Pane, Fabrizio, additional, Patriarca, Andrea, additional, Pietrantuono, Giuseppe, additional, Plander, Mark, additional, Platzbecker, Uwe, additional, Prasad, Ritam, additional, Prejzner, Witold, additional, Rachow, Tobias, additional, Radinoff, Atanas, additional, Rejtő, László, additional, Rinaldi, Ciro, additional, Robak, Tadeusz, additional, Rodriguez, Maria Angeles Fernandez, additional, Ronson, Aaron, additional, Ross, David, additional, Sacha, Tomasz, additional, Sadjadian, Parvis, additional, Salar, Antonio, additional, Santillana, Guillermo Sanz, additional, Scheid, Christof, additional, Schmidt, Aline, additional, Severinsen, Marianne Tang, additional, Stoeva, Vera, additional, Szwedyk, Paweł, additional, Tiribelli, Mario, additional, Trautmann-Grill, Karolin, additional, Trottier, Amy, additional, Tzvetkov, Nikolay, additional, van Droogenbroeck, Janusz, additional, Vannucchi, Alessandro, additional, Verstovsek, Srdan, additional, Vianelli, Nicola, additional, von Bubnoff, Nikolas, additional, Wolf, Dominik, additional, Woszczyk, Dariusz, additional, Woźny, Tomasz, additional, Wróbel, Tomasz, additional, Xicoy, Blanca, additional, and Yeh, Su-Peng, additional

Published
2023
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37. RAPORT MEDYCZNEJ RACJI STANU: WYZWANIA ZDROWIA - POCZUCIE BEZPIECZEŃSTWA. PERSPEKTYWA 2022-2023. REPORT OF THE MEDICAL REASON OF STATE: HEALTH CHALLENGES - SENSE OF SECURITY. PERSPECTIVE 2022-2023

Author

Gierczyński, Jakub, Bidziński, Mariusz, Błażewicz, Grzegorz, Bogdanski, Pawel, Chmielewska-Wojciechowska, Katarzyna, Czech, Marcin, Czupryniak, Leszek, Władysław Duda, Małgorzata Gałązka-Sobotka, Gellert, Ryszard, Grenda, Ryszard, Hus, Marek, Jedrzejczak, Joanna, Kawecki, Maciej, Kwiatkowska, Brygida, Lisowska, Katarzyna, Łanda, Krzysztof, Mierzejewski, Piotr, Parkitna, Joanna, Płukis, Krystyna, Radecka, Barbara, Rejdak, Konrad, Roszkowska-Rzemieniecka, Ilona, Rutkowski, Piotr, Rychwalski, Grzegorz, Schymalla, Iwona, Śliwińska, Anna, Talar-Wojnarowska, Renata, Wechmann, Krystyna, Zajk, Violetta, and Zuber, Zbigniew Michal

Published
2023
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38. RAPORT: VII SPOTKANIE RADY EKSPERTÓW DS. CHORÓB RZADKICH MEDYCZNEJ RACJI STANU. REPORT: 7th MEETING OF THE COUNCIL OF EXPERTS FOR RARE DISEASES FOR A MEDICAL REASON

Author

Gierczyński, Jakub, Adamski, Jakub, Chrzanowska, Krystyna, Dwilewicz-Trojaczek, Jadwiga, Dziegielewski, Michal, Hus, Marek, Jarzab, Barbara, Kostera-Pruszczyk, Anna, Latos-Bieleńska, Anna, Malecka-Wojcieszko, Ewa, Meder, Janusz, Mierzejewski, Piotr, Schymalla, Iwona, Michał Sutkowski, Styczynski, Jan, Cegielska, Jolanta Sykut, Wysoczański, Wojciech, Zuber, Zbigniew Michal, and Zurowska, Aleksandra

Published
2023
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41. Momelotinib (MMB) Long-Term Safety: Pooled Data from Three Phase 3 Randomized-Controlled Trials (RCTs)

Author

Verstovsek, Srdan, primary, Mesa, Ruben, additional, Gupta, Vikas, additional, Lavie, David, additional, Dubruille, Viviane, additional, Cambier, Nathalie, additional, Platzbecker, Uwe, additional, Hus, Marek, additional, Xicoy, Blanca, additional, Oh, Stephen T, additional, Kiladjian, Jean-Jacques, additional, Vannucchi, Alessandro M, additional, Gerds, Aaron T., additional, Egyed, Miklos, additional, Mayer, Jiri, additional, Sacha, Tomasz, additional, Kawashima, Jun, additional, Morris, Marc, additional, Huang, Mei, additional, and Harrison, Claire, additional

Published
2022
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42. A Comparison of Outcomes in Patients with Secondary Acute Promyelocytic Leukemia (APL) and De Novo APL - a Case-Match Retrospective Analysis of Polish Adult Leukemia Group (PALG)

Author

Pluta, Agnieszka, primary, Sobas, Marta Anna, additional, Mikulski, Damian, additional, Krawiec, Kinga, additional, Czemerska, Magdalena, additional, Budziszewska, Bozena Katarzyna, additional, Wróbel, Tomasz, additional, Watek, Marzena, additional, Lech-Marańda, Ewa, additional, Gromek, Tomasz, additional, Hawrylecka, Dorota, additional, Hus, Marek, additional, Zarzycka, Ewa, additional, Zaucha, Jan, additional, Armatys, Anna, additional, Helbig, Grzegorz, additional, Oleksiuk, Jolanta, additional, Piszcz, Jaroslaw, additional, Szczepaniak, Andrzej, additional, Gil, Lidia, additional, Becht, Rafal, additional, Fendler, Wojciech, additional, Giebel, Sebastian, additional, and Wierzbowska, Agnieszka, additional

Published
2022
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43. Prospective Assessment of Measurable Residual Disease Kinetics in Intensively Treated Patients with Acute Myeloid Leukemia - Results of the Polish Adult Leukemia Group PALG-AML1/2016 Study

Author

Wierzbowska, Agnieszka, primary, Pluta, Agnieszka, additional, Czyz, Anna, additional, Libura, Marta Antonina, additional, Giebel, Sebastian, additional, Stelmach, Piotr, additional, Czemerska, Magdalena, additional, Strzałka, Piotr, additional, Kopinska, Anna, additional, Wozniczka, Krzysztof, additional, Helbig, Grzegorz, additional, Wojcik, Karol, additional, Razny, Malgorzata, additional, Sobas, Marta Anna, additional, Wróbel, Tomasz, additional, Szczepaniak, Andrzej, additional, Gil, Lidia, additional, Dutka, Magdalena, additional, Bieniaszewska, Maria, additional, Gromek, Tomasz, additional, Hus, Marek, additional, Cichocka, Edyta, additional, Halka, Janusz, additional, Patkowska, Elzbieta, additional, Watek, Marzena, additional, Wozniak, Jolanta, additional, Lech-Marańda, Ewa, additional, Kopacz, Agnieszka, additional, Dulik, Katarzyna, additional, Holowiecki, Jerzy, additional, Soin, Michal, additional, Mikulski, Damian, additional, Perdas, Ewelina, additional, Fendler, Wojciech, additional, Sukkur, Ameenah, additional, Rustani, Andi, additional, Mencia Trinchant, Nuria, additional, Desai, Pinkal, additional, Lee, Sangmin, additional, Samuel, Michael, additional, Kaner, Justin D., additional, Ritchie, Ellen, additional, Guzman, Monica L., additional, and Roboz, Gail J., additional

Published
2022
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44. A Polish Acute Leukemia Group Prospective Multicenter Clinical Trial to Compare the Efficacy of Two Standard Induction Therapies (DA-90 vs DAC) and Two Standard Salvage Regimens (FLAG-IDA vs CLAG-M) in Acute Myeloid Leukemia (AML) Patients ≤ 60 Years Old (PALG-AML1/2016)

Author

Wierzbowska, Agnieszka, primary, Czyz, Anna, additional, Pluta, Agnieszka, additional, Libura, Marta Antonina, additional, Giebel, Sebastian, additional, Stelmach, Piotr, additional, Czemerska, Magdalena, additional, Krawiec, Kinga, additional, Kopinska, Anna, additional, Wozniczka, Krzysztof, additional, Helbig, Grzegorz, additional, Halka, Janusz, additional, Sobas, Marta Anna, additional, Wróbel, Tomasz, additional, Szczepaniak, Andrzej, additional, Gil, Lidia, additional, Dutka, Magdalena, additional, Bieniaszewska, Maria, additional, Gromek, Tomasz, additional, Hus, Marek, additional, Patkowska, Elzbieta, additional, Watek, Marzena, additional, Lech-Marańda, Ewa, additional, Kopacz, Agnieszka, additional, Dulik, Katarzyna, additional, Holowiecki, Jerzy, additional, Obara, Agata, additional, Cichocka, Edyta, additional, Gawronski, Krzysztof, additional, Mordak-Domagala, Monika, additional, Sukkur, Ameenah, additional, Rustani, Andi, additional, Desai, Pinkal, additional, Samuel, Michael, additional, Mencia Trinchant, Nuria, additional, Lee, Sangmin, additional, Kaner, Justin D., additional, Ritchie, Ellen, additional, Guzman, Monica L., additional, and Roboz, Gail J., additional

Published
2022
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47. Acute intermittent porphyria: a diagnostic challenge.

Author

Bigosiński, Karol, Dubaj, Maciej, Szudy-Szczyrek, Aneta, and Hus, Marek

Subjects
ACUTE intermittent porphyria, DIGESTIVE system diseases, SYMPTOMS, COMA
Abstract

The article describes the case of a 29-year-old female who was admitted to the surgical ward of a regional hospital in June 2017 because of severe abdominal pain and vomiting of several days' duration. Topics include treatment given to the patient, a diagnosis of the overt form of acute intermittent porphyria (AIP), and clinical characteristics of AIP.

Published
2024
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