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Your search keyword '"Hwang, Jenie Yoonoo"' showing total 38 results
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38 results on '"Hwang, Jenie Yoonoo"'

7. Novel Anorexigenic Effects of Vaspin.

Author

Kim, Min Seon, primary, Lee, Ki-Up, additional, Park, Joong-Yeol, additional, Je Lee, Woo, additional, Koh, Eun Hee, additional, Ah Lee, Sang, additional, Shin, Mi-Seon, additional, Hwang, Jenie Yoonoo, additional, Kang, Gil-Myung, additional, Lee, Ju Young, additional, and Youn, Byung Soo, additional

Published
2010
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14. Association of prediabetes, defined by fasting glucose, HbA1c only, or combined criteria, with the risk of cardiovascular disease in Koreans

Author

Kim, Hong-Kyu, primary, Lee, Jung Bok, additional, Kim, Seon Ha, additional, Jo, Min-Woo, additional, Kim, Eun Hee, additional, Hwang, Jenie Yoonoo, additional, Bae, Sung Jin, additional, Jung, Chang Hee, additional, Lee, Woo Je, additional, Park, Joong-Yeol, additional, Park, Gyung-Min, additional, Kim, Young-Hak, additional, and Choe, Jaewon, additional

Published
2016
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22. Association of Apolipoprotein B/Apolipoprotein A1 Ratio and Coronary Artery Stenosis and Plaques Detected by Multi-Detector Computed Tomography in Healthy Population

Author

Jung, Chang Hee, primary, Hwang, Jenie Yoonoo, additional, Shin, Mi Seon, additional, Yu, Ji Hee, additional, Kim, Eun Hee, additional, Bae, Sung Jin, additional, Yang, Dong Hyun, additional, Kang, Joon-Won, additional, Park, Joong-Yeol, additional, Kim, Hong-Kyu, additional, and Lee, Woo Je, additional

Published
2013
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35. Association of metabolically healthy obesity with subclinical coronary atherosclerosis in a Korean population.

Author

Jung, Chang Hee, Lee, Min Jung, Hwang, Jenie Yoonoo, Jang, Jung Eun, Leem, Jaechan, Yang, Dong Hyun, Kang, Joon‐Won, Kim, Eun Hee, Park, Joong‐Yeol, Kim, Hong‐Kyu, and Lee, Woo Je

Subjects
ATHEROSCLEROSIS, OBESITY, CORONARY artery stenosis, HEART disease research, METABOLISM
Abstract

Objective The degree of subclinical coronary atherosclerosis detected by coronary multidetector computed tomography (MDCT) in four groups defined by the state of metabolic health and obesity in an asymptomatic Korean population was compared. Methods The data of 4009 asymptomatic subjects who participated in a routine health screening examination were collected. Significant coronary artery stenosis defined as >50% stenosis, plaque, and coronary artery calcium scores (CACS) were assessed by MDCT. Participants were stratified by BMI (cut-off value, 25 kg/m2) and metabolically healthy state, which was defined by Wildman criteria. Results Metabolically healthy obese (MHO) subjects had a significantly higher prevalence of significant subclinical coronary atherosclerotic burden compared with metabolically healthy nonobese (MHNO) subjects. The adjusted odds ratios of the MHO group for various coronary MDCT findings (MHNO group as the reference), such as coronary artery stenosis, any plaque, calcified plaque, mixed plaque, CACS > 0, and CACS > 100, were 1.87 (95% CI 1.15-3.03), 1.31 (1.01-1.71), 1.40 (1.05-1.86), 1.57 (1.01-2.48), 1.38 (1.04-1.82), and 1.69 (1.03-2.78), respectively. Conclusions Our data illustrate that MHO subjects have substantial subclinical coronary atherosclerotic burden. Thus, it is important to consider the metabolic health state and obesity in evaluating cardiovascular risk. [ABSTRACT FROM AUTHOR]

Published
2014
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37. Higher serum bilirubin level as a protective factor for the development of diabetes in healthy Korean men: a 4 year retrospective longitudinal study.

Author

Jung CH, Lee MJ, Kang YM, Hwang JY, Jang JE, Leem J, Park JY, Kim HK, and Lee WJ

Subjects
Adult, Aged, Aged, 80 and over, Blood Glucose metabolism, Diabetes Mellitus, Type 2 blood, Diabetes Mellitus, Type 2 epidemiology, Humans, Incidence, Insulin Resistance, Longitudinal Studies, Male, Middle Aged, Multivariate Analysis, Reference Values, Republic of Korea epidemiology, Retrospective Studies, Triglycerides blood, Bilirubin blood, Diabetes Mellitus, Type 2 prevention & control
Abstract

Objective: Bilirubin, a natural product of heme catabolism by heme oxygenase, one of key antioxidant enzymes, has been recognized as a substance with potent antioxidant and cytoprotective properties. Several studies have shown a significant negative relationship between serum bilirubin levels and the risk of metabolic disorders, including type 2 diabetes. However, longitudinal studies investigating the association of elevated serum bilirubin levels and type 2 diabetes are lacking. In the present study, we aimed to investigate the longitudinal effects of baseline serum bilirubin concentrations on the development of type 2 diabetes in healthy Korean men., Materials and Methods: This 4 year retrospective longitudinal observational study was conducted at the Asan Medical Center, Seoul, Republic of Korea. The study population consisted of 5960 men without type 2 diabetes who underwent routine health examinations in 2007 (baseline) and 2011 (follow-up). Baseline serum bilirubin concentrations were determined by the vanadate oxidation method., Results: During a 4 year period, 409 incident cases of diabetes (6.9 %) were identified. Incident type 2 diabetes decreased across the baseline bilirubin quartile categories (P for trend <0.001). In multivariable-adjusted model, the relative risk (RR) for the development of type 2 diabetes was significantly lower in the highest (i.e., 1.30-2.00 mg/dl) than in the lowest bilirubin quartile category (i.e., ≤ 0.90 mg/dl), even after adjustment for confounding variables (RR=0.69, 95% confidence interval 0.48-0.99, P for trend = 0.041)., Conclusions: The results indicate that serum total bilirubin level may provide additional information for predicting future development of type 2 diabetes in healthy subjects., (© 2013.)

Published
2014
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38. The duration of sulfonylurea treatment is associated with β-cell dysfunction in patients with type 2 diabetes mellitus.

Author

Shin MS, Yu JH, Jung CH, Hwang JY, Lee WJ, Kim MS, and Park JY

Subjects
Blood Glucose drug effects, Blood Glucose metabolism, C-Peptide drug effects, Diabetes Mellitus, Type 2 physiopathology, Fasting blood, Female, Follow-Up Studies, Humans, Insulin-Secreting Cells drug effects, Male, Middle Aged, Prospective Studies, Republic of Korea, C-Peptide blood, Diabetes Mellitus, Type 2 blood, Diabetes Mellitus, Type 2 drug therapy, Hypoglycemic Agents pharmacology, Insulin-Secreting Cells metabolism, Sulfonylurea Compounds pharmacology
Abstract

Background: This study investigated the incidence of β-cell dysfunction and the clinical and biochemical factors affecting that in patients with type 2 diabetes having more than 3 years of follow-up., Subjects and Methods: β-Cell dysfunction was assessed by measuring changes in the fasting serum C-peptide concentrations. Patients were classified into two groups: cases showing a decreased (Group D) or an unchanged or increased (Group I) C-peptide concentration from the baseline., Results: Of the 504 patients included in this study, 259 (51%) showed decreased C-peptide concentrations, of whom 20% showed a decrease of ≥50%. Most patients, however, had a final C-peptide concentration of ≥1 ng/mL, with only 18 (4%) individuals having a level <0.6 ng/mL. Patients in Group D had a longer duration of diabetes, higher initial hemoglobin A1c concentration, and longer treatment durations with sulfonylurea and insulin compared with Group I. After adjusting for diabetes duration and C-peptide follow-up period, the duration of sulfonylurea treatment was found to be the only factor independently associated with decreases in the C-peptide concentration., Conclusions: Although β-cell function deteriorates over time in patients with type 2 diabetes, these cases mainly have fasting serum C-peptide concentrations of ≥1 ng/mL. A longer treatment duration with sulfonylurea is associated with a more rapid decline in the C-peptide concentration.

Published
2012
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