1. Acute Liver Injury and Bilateral Pulmonary Artery Thrombosis Due to Hypereosinophilic Syndrome.
- Author
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Ouchi K, Okamoto H, Inoue J, Kobayashi S, Nagai H, Okamoto D, Manaka T, Nozawa Y, and Masamune A
- Subjects
- Humans, Male, Middle Aged, Fatal Outcome, Thrombosis etiology, Thrombosis diagnostic imaging, Thrombosis diagnosis, Tomography, X-Ray Computed, Acute Disease, Liver Diseases etiology, Liver Diseases diagnosis, Liver Diseases diagnostic imaging, Hypereosinophilic Syndrome complications, Hypereosinophilic Syndrome diagnosis, Pulmonary Artery diagnostic imaging, Pulmonary Artery pathology
- Abstract
A 46-year-old Japanese man was referred to our hospital because of a marked increase in his eosinophil count (22,870/μL) and elevated liver enzyme levels. Computed tomography (CT) showed thrombi measuring approximately 8 cm in both femoral veins. A liver biopsy revealed eosinophilic infiltration, hepatocyte necrosis, fibrosis, and multiple thrombi. We suspected acute liver injury and deep vein thrombosis associated with hypereosinophilic syndrome and initiated steroids and heparin treatment. Four days after starting treatment, the patient experienced sudden chest pain and cardiopulmonary arrest. CT revealed bilateral pulmonary artery thrombosis, and despite administration of a tissue plasminogen activator, the patient died.
- Published
- 2024
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