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2. ChemInform Abstract: Facile Synthesis of 4-Substituted 3,4-Dihydro-1H-2,1,3-benzothiadiazine 2,2-Dioxides

Author

Hyun Seung Ban, Jong-Dae Lee, Hyun Wha Lim, Eun Hye Yang, Sang Ook Kang, Chai-Ho Lee, Hiroyuki Nakamura, and Guofan Jin

Subjects
chemistry.chemical_compound, chemistry, Benzothiadiazine, Intramolecular force, Heteroatom, Trifluoroacetic acid, General Medicine, Medicinal chemistry
Abstract

A new method for the preparation of 4-substituted 3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2-dioxides is described. Treatment of t-butyl N-phenylsulfamoylcarbamate derivatives (1) with different aldehydes afforded the corresponding intramolecular cyclized products 2 under trifluoroacetic acid conditions. © 2011 Wiley Periodicals, Inc. Heteroatom Chem 22:192–197, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/hc.20670

Published
2011
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