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Introduction Bipolar disorder is an episodic mood disorder that causes unusual shifts in mood and affects the ability to carry out day-to-day tasks. Aim Evaluation of the sexual function in men and women with bipolar disorder during remission. Methods 60 men and women with bipolar disorder and 60 age-matched control subjects were included. A Structured Clinical Interview of Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition was performed to confirm the diagnosis, and Hamilton Depression Rating Scale (HAM-D) to assess the depressive symptoms and Young Mania Rating Scale (YMRS) to assess the manic symptoms. We assessed sexual function in both sexes using international indices of erectile function for men and sexual function of women. Main Outcome Measures Scores of HAM-D, YMRS, Arabic versions of International Index of Erectile Function (IIEF) and female sexual function (FSFI). Results Depressive symptoms showed insignificant adverse correlation with the IIEF in men, whereas they revealed adverse significant correlations with the items of female sexual function index (FSFI) except pain (correlation coefficients [r] = 0.349 [P = .059], r = 0.680 [P < .001], r = 0.574 [P = .001], r = 0.517 [P = .003], r = 0.569 [P = .001], r = 0.532 [P = .002], r = 0.609 [P < .001], r = 0.342 [P = .065], respectively). Interestingly, the manic symptoms were associated with sexual hyperfunctioning in the men and were insignificantly correlated with the different items of FSFI in the women (r = 0.414 [P = .023], r = 0.043 [P = .821], r = 0.100 [P = .601], r = 0.108 [P = .571], r = 0.183 [P = .332), r = 0.086 [P = .651], r = 0.022 (P = .907), r = 0.109 [P = .565], respectively). There was a positive correlation between the affected women’s satisfaction and their partners’ score (r = 0.374, P =.042). Finally, the mean score of pain was statistically higher in the female cases than the normal ones (mean ± SD = 3.6 ± 0.4, 3.4, ± 0.6; P = .036). Clinical implications A different approach may be mandatory for manic female patients. Strengths & Limitations This study is one of the few studies that evaluated the sexual function in patients with bipolar disorder especially during remission. Some limitations of this study must be mentioned. We failed to evaluate the female partners of the diseased males. Quality of life of the recruited patients was not assessed. Finally, the study included patients who were not drug free. Conclusion Manic symptoms in female bipolar I patients are associated with sexual hypofunctioning.

Objective To correlate late spermatid score and sperm count in men with normal semen analysis and oligozoospermia undergoing intracytoplasmic sperm injection (ICSI) to set the average threshold of spermatids/tubule of testicular tissue needed for normal sperm count/ml of semen. Material and methods This study was conducted on 24 normozoospermic subjects and 18 oligozoospermic patients who underwent wide bore needle biopsy because of failed sperm collection at the day of ICSI. Clinical data were reviewed and testicular biopsy slides were examined for Johnson score and adjusted late spermatid score. Results The optimum cut off value for adjusted late spermatid score in predicting a sperm count >20 million/ml was 20.75 late spermatid per tubule with 100% specificity. Model equations were produced to predict the sperm count using adjusted late spermatid score and vice versa. Conclusion This work supports the hypothesis that late spermatid score is a simple and reliable method for quantitation of spermatogenesis and it correlates well with the sperm count. The value of late spermatids needed for normal sperm count in this report is different from some other reports. The better standardization of work in this study may help resetting a new late spermatid threshold for normal sperm count.

L’oesophagite a eosinophiles est une pathologie chronique allergique rare, de description recente. Les premiers cas ont ete publies en 1977. Depuis, l’entite est de plus en plus rapportee dans la litterature medicale.