168 results on '"Iacob, Roxana E."'
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2. Combination of HDX-MS and in silico modeling to study enzymatic reactivity and stereo-selectivity at different solvent conditions
3. Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments
4. Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7
5. Supplementary Table S12 from Tissue-Specific Oncogenic Activity of KRASA146T
6. Supplementary Tables S14-S17 from Tissue-Specific Oncogenic Activity of KRASA146T
7. Data from Tissue-Specific Oncogenic Activity of KRASA146T
8. Supplementary Figures S1-S18 from Tissue-Specific Oncogenic Activity of KRASA146T
9. Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism
10. General structural features that regulate integrin affinity revealed by atypical αVβ8
11. Probing Conformational Dynamics of Tau Protein by Hydrogen/Deuterium Exchange Mass Spectrometry
12. Hydrogen-Deuterium Exchange Mass Spectrometry to Study Protein Complexes
13. Characterization of Aggregation Propensity of a Human Fc-Fusion Protein Therapeutic by Hydrogen/Deuterium Exchange Mass Spectrometry
14. Dynamics of integrin α5β1, fibronectin, and their complex reveal sites of interaction and conformational change
15. Hydrogen/deuterium exchange mass spectrometry for probing higher order structure of protein therapeutics: methodology and applications
16. Investigating Monoclonal Antibody Aggregation Using a Combination of H/DX-MS and Other Biophysical Measurements
17. Von Willebrand factor A1 domain stability and affinity for GPIbα are differentially regulated by its O-glycosylated N- and C-linker
18. Force interacts with macromolecular structure in activation of TGF-β
19. Author response: Von Willebrand factor A1 domain stability and affinity for GPIbα are differentially regulated by its O-glycosylated N- and C-linker
20. Protection of the Prodomain α1-Helix Correlates with Latency in the Transforming Growth Factor-β Family
21. Von Willebrand factor A1 domain affinity for GPIbα and stability are differentially regulated by its O-glycosylated N-linker and C-linker
22. The Influence of Adnectin Binding on the Extracellular Domain of Epidermal Growth Factor Receptor
23. Dynamics of integrin α5β1, fibronectin, and their complex reveal sites of interaction and conformational change.
24. Protection of the prodomain α1-helix correlates with latency in the transforming growth factor-β family
25. Hydrogen Exchange Mass Spectrometry: Are We Out of the Quicksand?
26. Mass Spectrometric Characterization of Glycosylation of Hepatitis C Virus E2 Envelope Glycoprotein Reveals Extended Microheterogeneity of N-Glycans
27. Targeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitors
28. Novel mutant-selective EGFR kinase inhibitors against EGFR T790M
29. Conformational disturbance in Abl kinase upon mutation and deregulation
30. Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors
31. Tissue-Specific Oncogenic Activity of KRASA146T
32. Fusion surface structure, function, and dynamics of gamete fusogen HAP2
33. Author response: Fusion surface structure, function, and dynamics of gamete fusogen HAP2
34. Abstract 3354: Chemically induced degradation of the transcription factor BCL6
35. Tolloid cleavage activates latent GDF8 by priming the pro‐complex for dissociation
36. Molecular characterization of the β-amyloid(4-10) epitope of plaque specific Aβ antibodies by affinity-mass spectrometry using alanine site mutation
37. Probing Conformational Dynamics of Tau Protein by Hydrogen/Deuterium Exchange Mass Spectrometry
38. Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6
39. Tolloid cleavage activates latent GDF8 by priming the pro-complex for dissociation
40. Characterization of Aggregation Propensity of a Human Fc-Fusion Protein Therapeutic by Hydrogen/Deuterium Exchange Mass Spectrometry
41. Investigating the Structural Dynamics of Oncogenic Histone Methyltransferases
42. Hydrogen/deuterium exchange mass spectrometry applied to IL-23 interaction characteristics: potential impact for therapeutics
43. Targeting wild-type and T315I Bcr-Abl by combining allosteric with ATP-site inhibitors
44. Applications of Hydrogen/Deuterium Exchange MS from 2012 to 2014
45. Differential Sensitivity of Src-Family Kinases to Activation by SH3 Domain Displacement
46. Electron Transfer Control in Soluble Methane Monooxygenase
47. Correction: Corrigendum: Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors
48. Enhanced SH3/Linker Interaction Overcomes Abl Kinase Activation by Gatekeeper and Myristic Acid Binding Pocket Mutations and Increases Sensitivity to Small Molecule Inhibitors*
49. Structure and Dynamic Regulation of Abl Kinases*
50. The Natural Product Cucurbitacin E Inhibits Depolymerization of Actin Filaments
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