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Your search keyword '"Ibrahima Kéita"' showing total 4 results
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4 results on '"Ibrahima Kéita"'

1. Acceptability, barriers and facilitators of using dried blood spots-point-of-care testing for sickle cell disease in Africa: an implementation science protocol for a multinational qualitative study

Author

Andre Pascal Kengne, Leon Tshilolo, Grace Ndeezi, Nicola Mulder, Moses Joloba, Victoria Nembaware, Nchangwi Syntia Munung, Vivian Paintsil, Emmanuel Peprah, Fred Stephen Sarfo, Deogratias Munube, Collen Masimirembwa, Ambroise Wonkam, Daniel Ansong, Kwaku Ohene-Frempong, Ezekiel Mupere, Sarah Kiguli, Julie Makani, Josephine Mgaya, Siana Nkya, Fred Semitala, Raphael Zozimus Sangeda, Emmanuel Balandya, Anazoeze Madu, Catherine Chunda-Liyoka, Yeya Dit Sadio Sarro, Daudi Jjingo, Obiageli Eunice Nnodu, Lulu Chirande, Boubacari Ali Touré, Aldiouma Guindo, Patience Kuona, Kevin Esoh, Mario Jonas, Maxwell Nwegbu, Upendo Masamu, Jack Morrice, Patrick Ohiani Moru, Valentina Ngo Bitoungui, Hans Ackerman, Alex Osei Akoto, Emmanuela Ambrose, Evans Amuzu, Samuel Asala, Biobele Brown, Mmbando Bruno, Daima Bukini, Pamela Gorejena, Abdul Aziz Hassan, Justin Hokororo, Jade Hotchkiss, Abdoul Malik Idris, Hezekiah Isa, Agnes Jonathan, Gwendoline Q. Kandawasvika, Daniel Kandonga, Ibrahima Keita, Sekou Kene, Frank Makundi, Janeth Manongi, Hamakwa Mantina, Jason Maro, Irene Kida Minja, Khuthala Mnika, Takudzwa Mtisi, Wilson Mupfururirwa, Ritah Mutagonda, Ruth Namazzi, Solomon Ofori-Aquah, Emmanuel Okocha, Fumni Olopade, Jesca Ondego, Chandré Oosterwyk-Liu, Nash Oyekanmi, Stella Paul, Cynthia Phiri, Paschal Ruggajo, Parker Ruhl, Ian Machingura Ruredzo, Pauline Sambo, Sawabati Shabani, Florence Urio, and Robert Opoka

Subjects
Medicine
Abstract

Background Sickle cell disease (SCD) is a prevalent inherited blood disorder. Globally, approximately 515 000 babies are born with SCD annually, with 75% of these births occurring in Africa. Integrating newborn screening (NBS) for SCD into primary healthcare structures, such as immunisation programmes, holds significant promise, with dried blood spots (DBS)-point-of-care technologies (POCT) like HaemoTypeSC offering cost-effective screening solutions. However, scaling up DBS-POCT for NBS of SCD in Africa remains challenging.Objective This study aims to explore individual, organisational and external factors that may influence the reliability, feasibility, acceptability, adoption and sustainability of using DBS-POCT with HaemoTypeSC for NBS of SCD at primary healthcare centres in African countries.Method This qualitative study will be conducted in seven African countries that are part of the SickleInAfrica consortium sites. The study design is informed by the Consolidated Framework for Implementation Research (CFIR) and the Implementation Outcome Model. Participants will be mothers whose babies have been diagnosed with SCD, healthcare professionals and policy-makers. In-depth interviews and focus group discussions will be used for data collection. Data analysis will be through thematic analysis.Ethics and dissemination Research ethics approvals have been obtained from the seven countries. Written informed consent will be obtained from all participants. The study results will be disseminated in peer-reviewed scientific journals, scientific conferences, reports to national ministries of public health and webinars.

Published
2024
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3. [Platelet count in the steady state phase and clinical severity of sickle cell disease in a reference centre for sickle cell disease in Mali]

Author

Lamine, Diallo, Aldiouma, Guindo, Ibrahima, Kéita, Mohamed Ag, Baraïka, Abdoul Karim, Dembélé, Boubacari Ali, Touré, and Dapa Aly, Diallo

Subjects
Platelet Count, Humans, Prospective Studies, Anemia, Sickle Cell, Mali, Platelet Aggregation Inhibitors
Abstract

Risk factors associated with complications occurring in sickle cell disease are not fully elucidated. The purpose of this study was to evaluate the existence of an association between the clinical severity of sickle cell disease and platelet count in the steady state phase in patients with sickle cell disease followed up at the Center for Research and Control of Sickle Cell Disease in Bamako, Mali. We conducted a retrospective review of 40 medical records of patients aged 5 to 42 years with sickle cell disease at the Center for Research and Control of Sickle Cell Disease in Bamako, Mali. Clinical severity of sickle cell disease was assessed according to the criteria of VOC and/or hospitalizations2 or ≥ 2 per year. Data entry was carried out using the Excel 2013 version. The statistical tests used were the Chi2, Student and Mac Nemar tests. Of the 40 patients, 82.5% had haemolytic phenotype and 17.5% hyperviscous phenotype; complications of sickle cell disease were more frequent in the haemolytic phenotype group (p0.05). There was a significant association between mean platelet count ≥ 450 G/L in the steady state phase and the annual number of CVOs ≥ 2 (p = 0.002). This study shows that mean platelet count ≥ 450 G/L in sickle cell patients in the steady state phase could be a risk factor for the frequent occurrence of CVO. It underlines the importance of conducting prospective studies focusing on both hyperplateletosis and platelet activation markers in larger sample sizes, as well as therapeutic trials involving platelet activation inhibitors, such as Crizanlizumab, a humanised anti-P-selectin monoclonal antibodies.

Published
2021

4. Plaie iatrogene de l'artere carotide commune secondaire à un catheterisme veineux jugulaire interne

Author

Cheikh Ahmedou Lame, Birame Loum, Ibrahima Keita, Thierno Boubacar Diallo, and Alamasso Sow

Subjects
plaie artère carotide, cathétérisme veineux jugulaire interne, hématome cervical compressif, Medicine
Abstract

La plaie carotidienne lors du cathétérisme jugulaire veineux est un accident rare mais pouvant être dramatique. Nous rapportons un cas d'hématome cervical compressif avec hémothorax survenu à la suite d'une plaie de l'artère carotide commune au décours d'un cathétérisme veineux jugulaire interne. Le diagnostic et la prise en charge de ce type de complication sont discutés.

Published
2017
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