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12. The authors reply

Author

Ishida, H., Murata, N., Yamada, H., Nakada, H., Takeuchi, I., Shimomura, K., Fujioka, M., and Idezuki, Y.

Published
2001
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14. Guidelines for conducting economic outcomes studies for endoscopic procedures

Author

Taylor B, Guy J. Maddern, Marks G, Cuschieri A, Idezuki Y, Goh P, Greg V. Stiegmann, and Ferreira E

Subjects
medicine.medical_specialty, medicine.diagnostic_test, Cost–benefit analysis, business.industry, Public health, Endoscopy, Guidelines as Topic, Hernia, Inguinal, Health economy, medicine.disease, Surgery, Treatment Outcome, Costs and Cost Analysis, Hospital Information Systems, medicine, Thoracoscopy, Humans, Medical emergency, business, Laparoscopy
Published
1997

15. Proceedings of the 27th Annual Meeting Matsuyama, Japan, November 7–9, 1985

Author

Rogler, C. E., Muto, Yoshihiro, Uchimura, Masayuki, Kijima, Hiroshi, Watanabe, Hidenobu, Kakita, A., Kambayashi, M., Takahashi, T., Saji, Y., Tsuburaya, T., Uchino, J., Ogura, Yoshifumi, Yamagiwa, Hiroshi, Takehara, Y., Yamashita, K., Shimaguchi, Seikoh, Ariyama, Joe, Tomatsu, Sei, Oi, Itaru, Fuji, Tadasu, Noguchi, Takayoshi, Yamao, Kenji, Nakazawa, Saburo, Suzuki, H., Mizumoto, R., Kumon, Masamitu, Ogata, Takuro, Yamamoto, Kenichi, Sasaki, Kenichi, Kida, Hideo, Nimura, Yuji, Hayakawa, Naokazu, Kamiya, Junichi, Shionoya, Shigehiko, Hata, Yoshinobu, Uchino, Jun-Ichi, Yamane, Takaaki, Mori, Katsutaka, Kinoshita, Hiroaki, Inoue, Tadashi, Takayasu, Kenichi, Moriyama, Noriyuki, Makuuchi, Masatoshi, Takasaki, Ken, Tanaka, Seiichi, Shirakawa, K., Misaki, F., Shibue, Tadashi, Tanaka, Keizo, Asaka, Masahiro, Saito, Masao, Yamagata, Susumu, Utiyama, Yasuo, Kobayashi, K., Arakawa, T., Matsueda, Kei, Muraoka, Akira, Umeda, Noritsugu, Mizumachi, Shyuzi, Okita, Kiwamu, Sakaue, Hiroshi, Akamatsu, Kouichi, Aoki, Teruaki, Nagao, Fusahiro, Watanabe, Yozo, Kidokoro, Tsutomu, Nakano, Satoshi, Kumada, Takashi, Kondo, Takaharu, Hayakawa, Tetsuo, Ogawa, Michio, Matsuda, Yasuki, Mori, Takesada, Yasuda, Hideki, Atomi, Yutaka, Ohnishi, Norihito, Kuroda, Akira, Morioka, Yasuhiko, Satake, Katsusuke, Tsuchiya, Ryoichi, Isaji, Shuji, Mizumoto, Ryuji, Yamamoto, Masahiro, Saitoh, Yoichi, Takeda, Kazunori, Taguchi, Susumu, Funatomi, Hitoshi, Hatta, Yoshio, Ono, Mikiko, Itoshima, Tatsuya, Tanaka, Ryoji, Sato, Shunichi, Sugaya, Hitoshi, Futagawa, Shunji, Kobayashi, Kenichi, Kawasaki, Hironaka, Akamatsu, Kouichi, Ohkubo, Hirotada, Kawarada, Yoshifumi, Mizumoto, Ryuji, Hirasawa, Hiroyuki, Odaka, Michio, Isono, Kaichi, Miura, Soichiro, Hamada, Yoshiki, Bamba, Tadao, Chikamochi, Nobuo, Nezu, R., Okada, A., Okuno, Masahiro, Umeyama, Kaoru, Hiwatashi, Nobuo, Nakajima, Kazuyuki, Fuchigami, Tadahiko, Yao, Tsuneyoshi, Matsueda, Kei, Takazoe, Masakazu, Shoda, Ryosuke, Umeda, Noritsugu, Fukushima, T., Kawamoto, M., Mizutani, Kenji, Nakai, Katsuhiko, Aoki, Katsunori, Morioka, Satoru, Baba, Shozo, Sakamoto, Akio, Usui, Sadahito, Fukuda, Yoshihiro, Tamura, Kazutami, Watanabe, Hikaru, Ueno, Takato, Tanikawa, Kyuichi, Oda, Masaya, Morizane, Toshio, Hashimoto, Hiroyuki, Akamatsu, Kouichi, Shimizu, Ichiro, Shima, Kenji, Sasaki, Kohsuke, Okita, Kiwamu, Suzuki, Toshimitsu, Seto, Yoshifumi, Nakashima, Toshiaki, Kiyosawa, Kendo, Imai, Haruhiko, Shimizu, Yukihiro, Sasaki, Hiroshi, Mori, Teruo, Mori, Yoshio, Ogawa, Makoto, Wakashin, Masafumi, Okuda, Kunio, Kawamoto, Chiaki, Ido, Kenichi, Fujise, Kiyotaka, Nagamori, Seishi, Fujikura, Shinichiro, Shimada, Kazuhiko, Yamaguchi, Kazuhito, Fujimura, Yoshinori, Kihara, Tsuyoshi, Kitamura, Hironobu, Fujiyama, Yoshihide, Asakura, Hitoshi, Kobayashi, Kensuke, Nagura, Hiroshi, Koshikawa, Takashi, Murata, Yuji, Kuroe, Kiyoo, Kawanishi, H., Koyama, K., Senda, S., Kiely, J., Harima, Kazuo, Fuji, Tadasu, Furukawa, Masato, Nakata, Toshinori, Kawahara, Hiroyuki, Komi, Nobuhiko, Ishihara, Yukio, Kondo, Satoshi, Nimura, Yuji, Suda, Koichi, Miyano, Takeshi, Inui, Kazuo, Ohnuma, Toshikazu, Hata, Yoshinobu, Uchino, Jun-Ichi, Yamamichi, Noboru, Konishi, Fumio, Morita, Nobuto, Tanikawa, Yutaka, Kitani, Eiichi, Tamura, Toshikazu, Komi, Nobuhiko, Ohta, Tetsuo, Konishi, Kohji, Utsumi, Makoto, Ueda, Noriyuki, Sasaki, Hideto, Ogura, Yoshifumi, Kawamoto, Toshio, Horiuchi, Itaru, Tada, Kouji, Akamatsu, Kouichi, Nakai, Teiko, Yamashita, Katsuko, Ninomiya, Fuyuhiko, Tanikawa, Kyuichi, Naito, Yasuo, Morita, Keiichi, Hachiya, Hitoshi, Takeuchi, Toshihiko, Onuki, Keizo, Ozaki, Toshihiko, Tsuchiya, Y., Nakamura, H., Nagashima, Hideyuki, Matsushiro, Takashi, Nakai, Masahiro, Isaji, Shuji, Takeuchi, K., Watanabe, G., Ito, T., Idezuki, Y., Isogai, Masatoshi, and Hachisuka, Kitao

Published
1986
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19. HEMOCOMPATIBILITY OF HEPARIN–FIXED IONEX

Author

Kanai, F., Takahama, T., Onishi, K., Hiraishi, M., Fujimori, Y., Yamazaki, Z., Idezuki, Y., Asano, K., Inoue, N., Kazama, M., Takiuchi, H., Itagaki, T., Kunitomo, T., Mori, Y., and Tanzawa, H.

Published
1985

36. Influence of trocar placement and CO2 pneumoperitoneum on port site metastasis following laparoscopic tumor surgery.

Author

Ishida, H., Murata, N., Yamada, H., Nomura, T., Shimomura, K., Fujioka, M., and Idezuki, Y.

Abstract

Background: The mechanisms involved in the development of port site metastasis following laparoscopic tumor surgery remain controversial. Therefore, we decided to investigate the influence of trocar placement and CO2 pneumoperitoneum on abdominal wound implantation in relation to intraperitoneal tumor growth in a rabbit model. Methods: Rabbits received either CO2 pneumoperitoneum with insertion of nine trocars (pneumoperitoneum group, n= 15), insertion of nine trocars alone (nonpneumoperitoneum group, n= 15), or nine abdominal incisions (control group, n= 13) 3 days after intraperitoneal inoculation of VX2 cancer cells. Results: The frequency of overall wound implantation on day 17 in the pneumoperitoneum group (24.4%) and nonpneumoperitoneum group (27.4%) tended to be higher than that in the control group (15.3%) ( p= 0.06). There was no significant difference among the three groups in the growth of cancer nodules on the omentum. Conclusions: The presence of a trocar may be a factor contributing to port site metastasis but CO2 pneumoperitoneum appears not to be a factor. [ABSTRACT FROM AUTHOR]

Published
2000
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37. Effects of non-shunting operation on azygos venous blood flow in cirrhotic patients.

Author

Kokudo, N, Kawasaki, S, Ohashi, K, Sakamoto, H, Koyama, H, Sanjo, K, and Idezuki, Y

Abstract

Azygos venous blood flow and other haemodynamic parameters were measured in 14 cirrhotic patients to investigate the effects of a non-shunting operation, oesophageal transection with paraoesophagogastric devascularisation. Azygos venous blood flow measured by the local continuous thermal dilution method was significantly reduced by 13.8% after the operation (428 (41) v 369 (33) ml/min). Hepatic venous pressure gradient (HVPG) was also significantly decreased from 14.5 (0.8) to 12.8 (0.7) mmHg (-11.8%). Cardiac output and routine liver tests did not change remarkably postoperatively. In this haemodynamic study before and after non-shunting operation, moderate but significant decreases were seen in azygos venous blood flow and portal pressure (HVPG), without substantial changes in systemic circulation. This suggests that blood flow through the portosystemic collaterals other than oesophageal varices may be decreased but still adequate after the operation. Well preserved portosystemic collaterals without oesophageal varices are thus considered an optimally balanced state after non-shunting operation. [ABSTRACT FROM PUBLISHER]

Published
1989

40. Extracorporkal Inmunoadsorption with In-ph or Imtr Column

Author

Yamazaki, Z., Idezuki, Y., Inoue, N., Yoshizawa, H., Yamawakl, N., Inagaki, K., and Tsuda, N.

Abstract

In order to selectively remove pathogenic macromolecular reactants, a biological affinity type adsorbent (a DNA colloidin charcoal column or protein A sepharose CL4R = Prosorba) has been developed and used for the treatment of immune disorders, alloimmunization and cancer. However, because physiologically active materials are required in this procedure, it is difficult to ensure an adequate supply of raw materials (and their handling, sterilization and preservation as an immunoadsorbent.TO overcome the above-mentionned problems, ve developed physico-chemical type immunoadsorbents IM-TR and IM-PH, which consist of polyvinyl alochol gel where tryptophan, in the former, and phenylalanine, in the latter, is used as a ligand. IM-PH has a better selectivitity than IM-TR, however, IM-TR is a more efficient adsorbent of anti-acethylcholine receptor antibody than IM-PH. IM-PH plasma perfusion has been successfully used with patients with rheumatoid arthritis, systemic lupus erythematosus (SLE), and multiple sclerosis (MS).

Published
1989
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41. Effect of Oral Adsorbent on Blood Metabolites in Hepatic Failure Dogs

Author

Hiraishi, M., Takahama, T., Yamazaki, Z., Kanai, F., Ohnishi, K., Idezuki, Y., and Inoue, N.

Abstract

AST-120 is a specially synthesized carbonaceous adsorbent for oral use. It mainly adsorbs low to middle molecules in the alimentary tract. In the present study, AST-120 was administered to hepatic failure dogs, and blood metabolites were analyzed by high performance liquid chromatography (HPLC).Thirty adult mongrel dogs underwent posta-cavae (P-C) shunts with 40% and 70% hepatectomies. They were divided into two groups, the AST group (n= 19) and control group (n=11). The AST group received about 0.5 g/kg of the adsorbent intermittently with diet after the operation. The control group was fed the ordinary diet. Body weight, blood ammonia, plasma bile acids were measured, and blood metabolites were analyzed by the multi-column HPLC system.P-C shunt dogs with 70% hepatotectomies died within three months showing about 40–50% body weight loss. HPLC analysis of their plasma showed some specific peaks for middle molecules, about 3000–5000 daltons. After administration of the adsorbent, these peaks were not detected, so it was considered that these substances had been adsorbed.

Published
1989
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43. Plasma Collection Using Nafamostat Mesilate and Dipyridamole as an Anticoagulant

Author

Hiraishi, M., Yamazaki, Z., Ichikawa, K., Kanai, F., Idezuki, Y., Onishi, K., Takahama, T., and Inoue, N.

Abstract

Nafamostat mesilate (FUT-175) is a strong protease inhibitor and is used as an anticoagulant in extracorporeal circulation. In the present study, we administered FUT and dipyridamole as anticoagulants during donor plasmapheresis, and the additional effect of dipyridamole was examined. In dogs weighing about 15 Kg, donor plasmapheresis was performed using a cellulose triacetate membrane plasmaseparator (PEX-15, Nipro), and 300 ml of filtrated plasma was obtained within 30 minutes. These dogs were divided into two groups, 50 mg/h of FUT alone was infused (group A, n=10), and the same dose of FUT and 25 mg/h of dipyridamole were infused (group B, n=5) during plasmapheresis. Changes of the coagulation system, blood cell counts and complement system were investigated. In clinical cases, an artificial liver support therapy using FUT as an anticoagulant was performed on 8 patients with acute liver failure, and blood compatibility was examined.In dogs, RBC counts and hematocrits were almost stable, but WBC counts were decreased to about 70% of the previous value. Platelets counts were about 60% and 80% of the previous value, in group A and group B, respectively, at the end of the plasmapheresis (P<0.01). Clotting factor VIII was diminished to about 20% and 35% of the previous value in group A and B, respectively. In clinical cases, all patients received the plasma exchange combined with hemodialysis using FUT as an anticoagulant, and no distinct side effect was observed during plasma exchange.

Published
1988
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44. Endoscopic balloon tamponade for emergency control of bleeding esophageal varices using a new transparent tamponade tube

Author

Hagiwara M, Idezuki Y, and Watanabe H

Subjects
medicine.medical_specialty, Balloon tamponade, medicine.medical_treatment, Biomedical Engineering, Biophysics, Lumen (anatomy), Bioengineering, Balloon, Esophageal and Gastric Varices, Biomaterials, Emergency control, medicine, Methods, Fiber Optic Technology, Humans, Esophagus, business.industry, Hemostatic Techniques, fungi, food and beverages, Endoscopy, General Medicine, medicine.anatomical_structure, Hemostasis, Tamponade, Radiology, Emergencies, Varices, business, Gastrointestinal Hemorrhage
Abstract

The endoscopic tamponade method, using a new transparent balloon tube, has been developed for the emergency control of bleeding esophageal varices. The introduction of the tube is performed while observing the esophagus utlizing a fiberoptic endoscope, which is inserted within the lumen of the tube so that the accidental injury to the mucosa can be avoided. The accurate diagnosis of the cause of bleeding is possible so that the most suitable form of treatment can be initiated without delay. Hemostasis is achieved with minimum balloon pressure, and the examination of the varices may be repeated, whenever desired, so that damage to the esophageal mucosa can be avoided. Deflation of the balloons and termination of the tamponade can be selected and planned so that the recurrence of bleeding immediately after the removal of the tube can be avoided. This method has so far been used successfully without any complications in 5 patients.

Published
1977

46. An Automated Plasma Collector with Innovative Membrane and Cassette-like Disposable Set

Author

YAMAZAKI, Z., primary, KANAI, F., additional, HIRAISHI, M., additional, OHNISHI, K., additional, IDEZUKI, Y., additional, TAKAHAMA, T., additional, FUJIMORI, Y., additional, ASANO, K., additional, INOUE, N., additional, SHIBATA, Y., additional, TAKENAKA, Y., additional, KAMATA, H., additional, ISHIHARA, J., additional, SUGIYAMA, S., additional, NISHI, H., additional, and FUKUMI, K., additional

Published
1986
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49. Immunoadsorption and Absorptive Cell Separation

Author

Yamazaki, Z., primary, Kanai, F., additional, Hiraishi, M., additional, Idezuki, Y., additional, Inoue, N., additional, Tsuda, N., additional, Katoh, H., additional, Ide, K., additional, Umegae, M., additional, and Ohno, K., additional

Published
1987
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