Search

Your search keyword '"Ieuan Day"' showing total 2 results
Start Over Author "Ieuan Day"
2 results on '"Ieuan Day"'

1. Epidemiology of SARS-CoV-2 infection among staff and students in a cohort of English primary and secondary schools during 2020–2021

Author

James R. Hargreaves, Sinéad M. Langan, William E. Oswald, Katherine E. Halliday, Joanna Sturgess, Jody Phelan, Patrick Nguipdop-Djomo, Benjamin Ford, Elizabeth Allen, Neisha Sundaram, Georgina Ireland, John Poh, Samreen Ijaz, Ian Diamond, Emma Rourke, Fiona Dawe, Alison Judd, Charlotte Warren-Gash, Taane G. Clark, Judith R. Glynn, W. John Edmunds, Chris Bonell, Punam Mangtani, Shamez N. Ladhani, Tanya Abramsky, Shazaad Ahmad, Felicity Aiano, Frances Baawuah, Urszula Bankiewicz, Sarah Batt, Joanne Beckmann, Ami Bhavsar, Bernadette Brent, Andrew Brent, Simon Brouwer, Kevin Brown, Richard Browne, Kevin Childs, Sarah Cook, Simon Cousens, Ieuan Day, Antonio Felton, Paul Fine, David Foster, Joanna Garstang, David Gates, Claire Grant, Bethany Griffiths-Tong, Claire Hele, Rowan Hemsi, Pete Jones, Helena Jordan, Adam Kucharski, Andrea Lacey, Rebecca Leeson, Ffion Lelii, Philip Lovely, Madeleine Lunskey, Chris McLanachan, James Munday, Ifeanyichukwu Okike, Kathleen O'Reilly, Penelope Parker, Annabel Powell, Sarah Proud, Mary Ramsay, Lee Rudd, Timothy Russell, Justin Shute, Nerissa Tilouche, Charmaine Virgin, Sian-Elin Wyatt, and KELLY YEO

Subjects
SARS-CoV-2, Schools, England, Public aspects of medicine, RA1-1270
Abstract

Summary: Background: There remains uncertainty about the epidemiology of SARS-CoV-2 among school students and staff and the extent to which non-pharmaceutical-interventions reduce the risk of school settings. Methods: We conducted an open cohort study in a sample of 59 primary and 97 secondary schools in 15 English local authority areas that were implementing government guidance to schools open during the pandemic. We estimated SARS-CoV-2 infection prevalence among those attending school, antibody prevalence, and antibody negative to positive conversion rates in staff and students over the school year (November 2020–July 2021). Findings: 22,585 staff and students participated. SARS-CoV-2 infection prevalence among those attending school was highest during the first two rounds of testing in the autumn term, ranging from 0.7% (95% CI 0.2, 1.2) among primary staff in November 2020 to 1.6% (95% CI 0.9, 2.3) among secondary staff in December 2020. Antibody conversion rates were highest in the autumn term. Infection patterns were similar between staff and students, and between primary and secondary schools. The prevalence of nucleoprotein antibodies increased over the year and was lower among students than staff. SARS-CoV-2 infection prevalence in the North-West region was lower among secondary students attending school on normal school days than the regional estimate for secondary school-age children. Interpretation: SARS-CoV-2 infection prevalence in staff and students attending school varied with local community infection rates. Non-pharmaceutical interventions intended to prevent infected individuals attending school may have partially reduced the prevalence of infection among those on the school site. Funding: UK Department of Health and Social Care.

Published
2022
Full Text
View/download PDF

2. A cluster randomised trial of the impact of a policy of daily testing for contacts of COVID-19 cases on attendance and COVID-19 transmission in English secondary schools and colleges

Author

Christopher W. White, Andrea Lacey, Urszula Bankiewicz, James McCrae, Peter W. Marks, Saroj Kendrick, Paul Staite, Bernadette C. Young, David Chapman, Emma Rourke, Tim E. A. Peto, Sarah Tunkel, Toby Nonnenmacher, Lisa Davies, Fegor Ichofu, Tom Fowler, Sylvester Smith, David W Eyre, Joseph F. Kelly, Ian Diamond, Susan R. Hopkins, Nick Hicks, George Beveridge, Ieuan Day, Lucy Yardley, Richard Ovens, Joseph Hillier, Fiona Dawe, and Ffion Jones

Subjects
medicine.medical_specialty, Intention-to-treat analysis, business.industry, Attendance, Odds ratio, Rate ratio, Disease cluster, Asymptomatic, Intervention (counseling), Physical therapy, medicine, Cluster randomised controlled trial, medicine.symptom, business
Abstract

SummaryBackgroundSchool-based COVID-19 contacts in England are asked to self-isolate at home. However, this has led to large numbers of missed school days. Therefore, we trialled daily testing of contacts as an alternative, to investigate if it would affect transmission in schools.MethodsWe performed an open-label cluster randomised controlled trial in students and staff from secondary schools and further education colleges in England (ISRCTN18100261). Schools were randomised to self-isolation of COVID-19 contacts for 10 days (control) or to voluntary daily lateral flow device (LFD) testing for school contacts with LFD-negative contacts remaining at school (intervention). Household contacts were excluded from participation.Co-primary outcomes in all students and staff were symptomatic COVID-19, adjusted for community case rates, to estimate within-school transmission (non-inferiority margin: FindingsOf 99 control and 102 intervention schools, 76 and 86 actively participated (19-April-2021 to 27-June-2021); additional national data allowed most non-participating schools to be included in the co-primary outcomes. 2432/5763(42.4%) intervention arm contacts participated. There were 657 symptomatic PCR-confirmed infections during 7,782,537 days-at-risk (59.1/100k/week) and 740 during 8,379,749 days-at-risk (61.8/100k/week) in the control and intervention arms respectively (ITT adjusted incidence rate ratio, aIRR=0.96 [95%CI 0.75-1.22;p=0.72]) (CACE-aIRR=0.86 [0.55-1.34]). There were 55,718 COVID-related absences during 3,092,515 person-school-days (1.8%) and 48,609 during 3,305,403 person-school-days(1.5%) in the control and intervention arms (ITT-aIRR=0.80 [95%CI 0.53-1.21;p=0.29]) (CACE-aIRR 0.61 [0.30-1.23]). 14/886(1.6%) control contacts providing an asymptomatic PCR sample tested positive compared to 44/2981(1.5%) intervention contacts (adjusted odds ratio, aOR=0.73 [95%CI 0.33-1.61;p=0.44]). Rates of symptomatic infection in contacts were 44/4665(0.9%) and 79/5955(1.3%), respectively (aOR=1.21 [0.82-1.79;p=0.34]).InterpretationDaily contact testing of school-based contacts was non-inferior to self-isolation for control of COVID-19 transmission. COVID-19 rates in school-based contacts in both intervention and control groups were

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results