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2. ARDS clinical practice guideline 2021

Author

Nakashima, Takuro, Masunaga, Aiko, Tanaka, Aiko, Inoue, Akihiko, Higashi, Akiko, Tanikawa, Atsushi, Ujiro, Atsushi, Takayama, Chihiro, Kasugai, Daisuke, Kawakami, Daisuke, Ueno, Daisuke, Satoh, Daizoh, Kai, Shinichi, Ota, Kohei, Hagiwara, Yoshihiro, Hamaguchi, Jun, Fujii, Ryo, Hongo, Takashi, Kishihara, Yuki, Masunaga, Naohisa, Yamamoto, Ryohei, Okazaki, Satoru Robert, Uchimido, Ryo, Terayama, Tetsuro, Hokari, Satoshi, Sakamoto, Hitoshi, Dongli, Nakataki, Emiko, Tabata, Erina, Okazawa, Seisuke, Kotajima, Futoshi, Ishimaru, Go, Hoshino, Haruhiko, Yoshida, Hideki, Iwai, Hidetaka, Nakagawa, Hiroaki, Sugimura, Hiroko, Narumiya, Hiromichi, Okano, Hiromu, Nakamura, Hiroshi, Sugimoto, Hiroshi, Hashimoto, Hiroyuki, Ito, Hiroyuki, Dote, Hisashi, Imahase, Hisashi, Sato, Hitoshi, Katsurada, Masahiro, Osawa, Ichiro, Kamei, Jun, Maki, Jun, Sugihara, Jun, Takeshita, Jun, Fujimoto, Junichi, Ishikawa, Junichi, Kosaka, Junko, Shibata, Junpei, Hashimoto, Katsuhiko, Nakano, Yasushi, Kikuyama, Kazuki, Shimizu, Kazushige, Okada, Kazuya, Kawano, Keishi, Anan, Keisuke, Ota, Keisuke, Kano, Ken-ichi, Asano, Kengo, Hondo, Kenichi, Ishii, Kenji, Fujita, Kensuke, Ogawa, Kenta, Ito, Kentaro, Tokunaga, Kentaro, Ishii, Kenzo, Kusumoto, Kohei, Takimoto, Kohei, Yamada, Kohei, Naito, Koichi, Yamashita, Koichi, Yoshinaga, Koichi, Yamauchi, Kota, Murata, Maki, Konda, Makiko, Hamamoto, Manabu, Aga, Masaharu, Kashiura, Masahiro, Ishikawa, Masami, Ozaki, Masayuki, Kono, Michihiko, Kyo, Michihito, Hayashi, Minoru, Abe, Mitsuhiro, Sato, Mitsunori, Sakai, Mizu, Kainuma, Motoshi, Tominaga, Naoki, Iguchi, Naoya, Nakagawa, Natsuki, Aoki, Nobumasa, Nishioka, Norihiro, Miyashita, Norihisa, Seki, Nozomu, Ikebe, Ryo, Imai, Ryosuke, Tate, Ryota, Sato, Ryuhei, Miyakawa, Sachiko, Kazuma, Satoshi, Nakano, Satoshi, Tetsumoto, Satoshi, Yoshimura, Satoshi, Yoshitake, Shigenori, Hoshi, Shin-etsu, Ohki, Shingo, Sato, Shintaro, Yoshihiro, Shodai, Ihara, Shoichi, Yamamoto, Shota, Koide, Shunichi, Kimata, Shunsuke, Saito, Shunsuke, Yasuo, Shunsuke, Sekine, Shusuke, Mimuro, Soichiro, Wada, Soichiro, Sugimura, Sosuke, Ishihara, Tadashi, Kaneko, Tadashi, Nagato, Tadashi, Maruhashi, Takaaki, Tamura, Takahiro, Ohno, Takanori, Ichiyama, Takashi, Niwa, Takashi, Ueji, Takashi, Ogura, Takayuki, Kawasaki, Takeshi, Tanaka, Takeshi, Umegaki, Takeshi, Furukawa, Taku, Omura, Taku, Nagao, Takumi, Mayumi, Takuya, Taniguchi, Takuya, Yoshida, Takuya, Shimatani, Tatsutoshi, Murata, Teppei, Sato, Tetsuya, Sawamoto, Tohru, Koukei, Yoshifumi, Takehara, Tomohiro, Ueda, Tomomi, Katsuta, Tomoya, Nishino, Tomoya, Yokoyama, Toshiki, Higashijima, Ushio, Iwanaga, Wataru, Inoue, Yasushi, Iwashita, Yoshiaki, Yamada, Yoshie, Kubota, Yoshifumi, Suido, Yoshihiro, Tomioka, Yoshihiro, Fujimoto, Yoshihisa, Fujita, Yoshihito, Yamaguchi, Yoshikazu, Nakamura, Yoshimi, Abe, Yoshinobu, Eguchi, Yoshitomo, Oshima, Yoshiyasu, Fukuda, Yosuke, Iwasaki, Yudai, Yasufuku, Yuichi, Shono, Yuji, Nakatani, Yuka, Nakamori, Yuki, Ito, Yukie, Tanabe, Yuko, Nagamine, Yusuke, Nakamura, Yuta, Kurihara, Yutaro, Tasaka, Sadatomo, Ohshimo, Shinichiro, Takeuchi, Muneyuki, Yasuda, Hideto, Ichikado, Kazuya, Tsushima, Kenji, Egi, Moritoki, Hashimoto, Satoru, Shime, Nobuaki, Saito, Osamu, Matsumoto, Shotaro, Nango, Eishu, Okada, Yohei, Hayashi, Kenichiro, Sakuraya, Masaaki, Nakajima, Mikio, Okamori, Satoshi, Miura, Shinya, Fukuda, Tatsuma, Kamo, Tetsuro, Yatabe, Tomoaki, Norisue, Yasuhiro, Aoki, Yoshitaka, Iizuka, Yusuke, Kondo, Yutaka, Narita, Chihiro, Taito, Shunsuke, Hayashi, Takuya, Terayama, Takero, Kataoka, Jun, Nishimura, Tetsuro, Yonekura, Hiroshi, Ando, Koichi, Yoshida, Takuo, Masuyama, Tomoyuki, and Sanui, Masamitsu

Published
2022
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4. Timing of tracheostomy and patient outcomes in critically ill patients requiring extracorporeal membrane oxygenation: a single-center retrospective observational study

Author

Nukiwa, Ryota, Uchiyama, Akinori, Tanaka, Aiko, Kitamura, Tetsuhisa, Sakaguchi, Ryota, Shimomura, Yoshimitsu, Ishigaki, Suguru, Enokidani, Yusuke, Yamashita, Tomonori, Koyama, Yukiko, Yoshida, Takeshi, Tokuhira, Natsuko, Iguchi, Naoya, Shintani, Yasushi, Miyagawa, Shigeru, and Fujino, Yuji

Published
2022
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8. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020)

Author

Egi, Moritoki, Ogura, Hiroshi, Yatabe, Tomoaki, Atagi, Kazuaki, Inoue, Shigeaki, Iba, Toshiaki, Kakihana, Yasuyuki, Kawasaki, Tatsuya, Kushimoto, Shigeki, Kuroda, Yasuhiro, Kotani, Joji, Shime, Nobuaki, Taniguchi, Takumi, Tsuruta, Ryosuke, Doi, Kent, Doi, Matsuyuki, Nakada, Taka-aki, Nakane, Masaki, Fujishima, Seitaro, Hosokawa, Naoto, Masuda, Yoshiki, Matsushima, Asako, Matsuda, Naoyuki, Yamakawa, Kazuma, Hara, Yoshitaka, Sakuraya, Masaaki, Ohshimo, Shinichiro, Aoki, Yoshitaka, Inada, Mai, Umemura, Yutaka, Kawai, Yusuke, Kondo, Yutaka, Saito, Hiroki, Taito, Shunsuke, Takeda, Chikashi, Terayama, Takero, Tohira, Hideo, Hashimoto, Hideki, Hayashida, Kei, Hifumi, Toru, Hirose, Tomoya, Fukuda, Tatsuma, Fujii, Tomoko, Miura, Shinya, Yasuda, Hideto, Abe, Toshikazu, Andoh, Kohkichi, Iida, Yuki, Ishihara, Tadashi, Ide, Kentaro, Ito, Kenta, Ito, Yusuke, Inata, Yu, Utsunomiya, Akemi, Unoki, Takeshi, Endo, Koji, Ouchi, Akira, Ozaki, Masayuki, Ono, Satoshi, Katsura, Morihiro, Kawaguchi, Atsushi, Kawamura, Yusuke, Kudo, Daisuke, Kubo, Kenji, Kurahashi, Kiyoyasu, Sakuramoto, Hideaki, Shimoyama, Akira, Suzuki, Takeshi, Sekine, Shusuke, Sekino, Motohiro, Takahashi, Nozomi, Takahashi, Sei, Takahashi, Hiroshi, Tagami, Takashi, Tajima, Goro, Tatsumi, Hiroomi, Tani, Masanori, Tsuchiya, Asuka, Tsutsumi, Yusuke, Naito, Takaki, Nagae, Masaharu, Nagasawa, Ichiro, Nakamura, Kensuke, Nishimura, Tetsuro, Nunomiya, Shin, Norisue, Yasuhiro, Hashimoto, Satoru, Hasegawa, Daisuke, Hatakeyama, Junji, Hara, Naoki, Higashibeppu, Naoki, Furushima, Nana, Furusono, Hirotaka, Matsuishi, Yujiro, Matsuyama, Tasuku, Minematsu, Yusuke, Miyashita, Ryoichi, Miyatake, Yuji, Moriyasu, Megumi, Yamada, Toru, Yamada, Hiroyuki, Yamamoto, Ryo, Yoshida, Takeshi, Yoshida, Yuhei, Yoshimura, Jumpei, Yotsumoto, Ryuichi, Yonekura, Hiroshi, Wada, Takeshi, Watanabe, Eizo, Aoki, Makoto, Asai, Hideki, Abe, Takakuni, Igarashi, Yutaka, Iguchi, Naoya, Ishikawa, Masami, Ishimaru, Go, Isokawa, Shutaro, Itakura, Ryuta, Imahase, Hisashi, Imura, Haruki, Irinoda, Takashi, Uehara, Kenji, Ushio, Noritaka, Umegaki, Takeshi, Egawa, Yuko, Enomoto, Yuki, Ota, Kohei, Ohchi, Yoshifumi, Ohno, Takanori, Ohbe, Hiroyuki, Oka, Kazuyuki, Okada, Nobunaga, Okada, Yohei, Okano, Hiromu, Okamoto, Jun, Okuda, Hiroshi, Ogura, Takayuki, Onodera, Yu, Oyama, Yuhta, Kainuma, Motoshi, Kako, Eisuke, Kashiura, Masahiro, Kato, Hiromi, Kanaya, Akihiro, Kaneko, Tadashi, Kanehata, Keita, Kano, Ken-ichi, Kawano, Hiroyuki, Kikutani, Kazuya, Kikuchi, Hitoshi, Kido, Takahiro, Kimura, Sho, Koami, Hiroyuki, Kobashi, Daisuke, Saiki, Iwao, Sakai, Masahito, Sakamoto, Ayaka, Sato, Tetsuya, Shiga, Yasuhiro, Shimoto, Manabu, Shimoyama, Shinya, Shoko, Tomohisa, Sugawara, Yoh, Sugita, Atsunori, Suzuki, Satoshi, Suzuki, Yuji, Suhara, Tomohiro, Sonota, Kenji, Takauji, Shuhei, Takashima, Kohei, Takahashi, Sho, Takahashi, Yoko, Takeshita, Jun, Tanaka, Yuuki, Tampo, Akihito, Tsunoyama, Taichiro, Tetsuhara, Kenichi, Tokunaga, Kentaro, Tomioka, Yoshihiro, Tomita, Kentaro, Tominaga, Naoki, Toyosaki, Mitsunobu, Toyoda, Yukitoshi, Naito, Hiromichi, Nagata, Isao, Nagato, Tadashi, Nakamura, Yoshimi, Nakamori, Yuki, Nahara, Isao, Naraba, Hiromu, Narita, Chihiro, Nishioka, Norihiro, Nishimura, Tomoya, Nishiyama, Kei, Nomura, Tomohisa, Haga, Taiki, Hagiwara, Yoshihiro, Hashimoto, Katsuhiko, Hatachi, Takeshi, Hamasaki, Toshiaki, Hayashi, Takuya, Hayashi, Minoru, Hayamizu, Atsuki, Haraguchi, Go, Hirano, Yohei, Fujii, Ryo, Fujita, Motoki, Fujimura, Naoyuki, Funakoshi, Hiraku, Horiguchi, Masahito, Maki, Jun, Masunaga, Naohisa, Matsumura, Yosuke, Mayumi, Takuya, Minami, Keisuke, Miyazaki, Yuya, Miyamoto, Kazuyuki, Murata, Teppei, Yanai, Machi, Yano, Takao, Yamada, Kohei, Yamada, Naoki, Yamamoto, Tomonori, Yoshihiro, Shodai, Tanaka, Hiroshi, and Nishida, Osamu

Published
2021
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15. Differential responses of cerebral and renal oxygenation to altered perfusion conditions during experimental cardiopulmonary bypass in sheep.

Author

Evans, Roger G., Cochrane, Andrew D., Hood, Sally G., Marino, Bruno, Iguchi, Naoya, Bellomo, Rinaldo, McCall, Peter R., Okazaki, Nobuki, Jufar, Alemayehu H., Miles, Lachlan F., Furukawa, Taku, Ow, Connie P. C., Raman, Jaishankar, May, Clive N., and Lankadeva, Yugeesh R.

Subjects
CARDIOPULMONARY bypass, PULSATILE flow, OXYGEN in the blood, OXYGEN saturation, NEAR infrared spectroscopy, PERFUSION, SHEEP
Abstract

We tested whether the brain and kidney respond differently to cardiopulmonary bypass (CPB) and to changes in perfusion conditions during CPB. Therefore, in ovine CPB, we assessed regional cerebral oxygen saturation (rSO2) by near‐infrared spectroscopy and renal cortical and medullary tissue oxygen tension (PO2), and, in some protocols, brain tissue PO2, by phosphorescence lifetime oximetry. During CPB, rSO2 correlated with mixed venous SO2 (r = 0.78) and brain tissue PO2 (r = 0.49) when arterial PO2 was varied. During the first 30 min of CPB, brain tissue PO2, rSO2 and renal cortical tissue PO2 did not fall, but renal medullary tissue PO2 did. Nevertheless, compared with stable anaesthesia, during stable CPB, rSO2 (66.8 decreasing to 61.3%) and both renal cortical (90.8 decreasing to 43.5 mm Hg) and medullary (44.3 decreasing to 19.2 mm Hg) tissue PO2 were lower. Both rSO2 and renal PO2 increased when pump flow was increased from 60 to 100 mL kg−1 min−1 at a target arterial pressure of 70 mm Hg. They also both increased when pump flow and arterial pressure were increased simultaneously. Neither was significantly altered by partially pulsatile flow. The vasopressor, metaraminol, dose‐dependently decreased rSO2, but increased renal cortical and medullary PO2. Increasing blood haemoglobin concentration increased rSO2, but not renal PO2. We conclude that both the brain and kidney are susceptible to hypoxia during CPB, which can be alleviated by increasing pump flow, even without increasing arterial pressure. However, increasing blood haemoglobin concentration increases brain, but not kidney oxygenation, whereas vasopressor support with metaraminol increases kidney, but not brain oxygenation. [ABSTRACT FROM AUTHOR]

Published
2024
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19. Association between tracheostomy and survival in patients with coronavirus disease 2019 who require prolonged mechanical ventilation for more than 14 days: A multicenter cohort study

Author

Tanaka, Aiko, primary, Uchiyama, Akinori, additional, Kitamura, Tetsuhisa, additional, Sakaguchi, Ryota, additional, Komukai, Sho, additional, Enokidani, Yusuke, additional, Koyama, Yukiko, additional, Yoshida, Takeshi, additional, Iguchi, Naoya, additional, Sobue, Tomotaka, additional, and Fujino, Yuji, additional

Published
2023
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22. Neutrophil gelatinase-associated lipocalin and liver-type fatty acid-binding protein as biomarkers for acute kidney injury after organ transplantation

Author

Iguchi, Naoya, Uchiyama, Akinori, Ueta, Kazuyoshi, Sawa, Yoshiki, and Fujino, Yuji

Subjects
Research, Health aspects, Organ transplantation -- Research -- Health aspects, Organ transplant recipients -- Prognosis -- Research, Biological markers -- Research
Abstract

Author(s): Naoya Iguchi[sup.1] , Akinori Uchiyama[sup.2] , Kazuyoshi Ueta[sup.2] , Yoshiki Sawa[sup.3] , Yuji Fujino[sup.2] Author Affiliations: (1) Intensive Care Unit, Osaka University Hospital, 2-15, Yamadaoka, 565-0871, Suita, Osaka, Japan [...], Purpose Neutrophil gelatinase-associated lipocalin (NGAL) and liver-type fatty acid-binding protein (L-FABP) are promising early biomarkers for acute kidney injury (AKI). In organ transplant recipients, AKI predictability based on NGAL and L-FABP remains to be elucidated. Furthermore, the association between serial NGAL and L-FABP measurements and AKI outcome is unknown. Therefore, we conducted a study to evaluate the ability of NGAL and L-FABP to predict AKI after organ transplantation and investigate the association between NGAL, L-FABP and AKI outcome. Methods Twenty-five organ transplant recipients admitted to the intensive care unit (ICU) immediately after transplant surgery were studied prospectively. Plasma NGAL (P-NGAL), urinary NGAL (U-NGAL) and L-FABP were measured from ICU admission to ICU discharge. U-NGAL and L-FABP were corrected for dilution/concentration by calculating U-NGAL/urine creatinine ratios (U-NGAL/Cr) and L-FABP/urine creatinine ratios (L-FABP/Cr). AKI was defined according to the Kidney Disease: Improving Global Outcomes criteria. Results AKI occurred in 11 patients. P-NGAL, U-NGAL/Cr and L-FABP/Cr upon ICU admission were unrelated to AKI development (p = 0.24, 0.22, and 0.53, respectively). There were no differences in P-NGAL, U-NGAL/Cr, and L-FABP/Cr levels from day 1 to day 6 between patients who did not recover from AKI and patients who recovered from AKI (p = 0.82, 0.26, and 0.61, respectively). Conclusion Our findings suggest that NGAL and L-FABP upon ICU admission are not predictive of AKI and serial NGAL and L-FABP measurements may be ineffective for monitoring the status and treatment of post-transplantation AKI.

Published
2015
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23. Additional file 1 of Association between early tracheostomy and patient outcomes in critically ill patients on mechanical ventilation: a multicenter cohort study

Author

Tanaka, Aiko, Uchiyama, Akinori, Kitamura, Tetsuhisa, Sakaguchi, Ryota, Komukai, Sho, Matsuyama, Tasuku, Yoshida, Takeshi, Tokuhira, Natsuko, Iguchi, Naoya, and Fujino, Yuji

Abstract

Additional file 1. Patients who underwent tracheostomy and overall hospital mortality at each institution.

Published
2022
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25. sj-pdf-1-prf-10.1177_02676591211013640 – Supplemental material for Dynamic responses of renal oxygenation at the onset of cardiopulmonary bypass in sheep and man

Author

Evans, Roger G, Cochrane, Andrew D, Hood, Sally G, Iguchi, Naoya, Marino, Bruno, Bellomo, Rinaldo, McCall, Peter R, Okazaki, Nobuki, Smith, Julian A, Zhu, Michael ZL, Ngo, Jennifer P, Noe, Khin M, Martin, Andrew, Thrift, Amanda G, Lankadeva, Yugeesh R, and May, Clive N

Subjects
FOS: Clinical medicine, Cardiology, 110323 Surgery
Abstract

Supplemental material, sj-pdf-1-prf-10.1177_02676591211013640 for Dynamic responses of renal oxygenation at the onset of cardiopulmonary bypass in sheep and man by Roger G Evans, Andrew D Cochrane, Sally G Hood, Naoya Iguchi, Bruno Marino, Rinaldo Bellomo, Peter R McCall, Nobuki Okazaki, Julian A Smith, Michael ZL Zhu, Jennifer P Ngo, Khin M Noe, Andrew Martin, Amanda G Thrift, Yugeesh R Lankadeva and Clive N May in Perfusion

Published
2021
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26. Additional file 1 of Incidence and management of metabolic acidosis with sodium bicarbonate in the ICU: An international observational study

Author

Fujii, Tomoko, Udy, Andrew A., Nichol, Alistair, Bellomo, Rinaldo, Deane, Adam M., El-Khawas, Khaled, Naorungroj Thummaporn, Neto, Ary Serpa, Bergin, Hannah, Short-Burchell, Robert, Chin-Ming Chen, Kuang-Hua Cheng, Kuo-Chen Cheng, Chia, Clemente, Feng-Fan Chiang, Nai-Kuan Chou, Fazio, Timothy, Pin-Kuei Fu, Ge, Victor, Hayashi, Yoshiro, Holmes, Jennifer, Hu, Ting-Yu, Shih-Feng Huang, Iguchi, Naoya, Jones, Sarah L., Karumai, Toshiyuki, Shinshu Katayama, Ku, Shih-Chi, Chao-Lun Lai, Bor-Jen Lee, Wen-Jinn Liaw, Ong, Chelsea T. W., Paxton, Lisa, Peppin, Chloe, Roodenburg, Owen, Shinjiro Saito, Santamaria, John D., Shehabi, Yahya, Tanaka, Aiko, Ravindranath Tiruvoipati, Hsiao-En Tsai, An-Yi Wang, Wang, Chen-Yu, Yeh, Yu-Chang, Chong-Jen Yu, and Kuo-Ching Yuan

Abstract

Additional file 1. Supplementary materials include detailed methods and supplementary results as referenced inthe article.

Published
2021
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28. Dynamic responses of renal oxygenation at the onset of cardiopulmonary bypass in sheep and man.

Author

Evans, Roger G, Cochrane, Andrew D, Hood, Sally G, Iguchi, Naoya, Marino, Bruno, Bellomo, Rinaldo, McCall, Peter R, Okazaki, Nobuki, Smith, Julian A, Zhu, Michael ZL, Ngo, Jennifer P, Noe, Khin M, Martin, Andrew, Thrift, Amanda G, Lankadeva, Yugeesh R, and May, Clive N

Subjects
CARDIAC surgery, OXYGEN, KIDNEYS, HEMOGLOBINS, ANIMAL experimentation, RENAL artery, THORACIC surgery, COMPARATIVE studies, T-test (Statistics), RENAL circulation, DESCRIPTIVE statistics, RESEARCH funding, REACTIVE oxygen species, CARDIOPULMONARY bypass, ACUTE kidney failure, OXYGEN in the body, HYPOXEMIA
Abstract

Introduction: The renal medulla is susceptible to hypoxia during cardiopulmonary bypass (CPB), which may contribute to the development of acute kidney injury. But the speed of onset of renal medullary hypoxia remains unknown. Methods: We continuously measured renal medullary oxygen tension (MPO2) in 24 sheep, and urinary PO2 (UPO2) as an index of MPO2 in 92 patients, before and after induction of CPB. Results: In laterally recumbent sheep with a right thoracotomy (n = 20), even before CPB commenced MPO2 fell from (mean ± SEM) 52 ± 4 to 41 ±5 mmHg simultaneously with reduced arterial pressure (from 108 ± 5 to 88 ± 5 mmHg). In dorsally recumbent sheep with a medial sternotomy (n = 4), MPO2 was even more severely reduced (to 12 ± 12 mmHg) before CPB. In laterally recumbent sheep in which a crystalloid prime was used (n = 7), after commencing CPB, MPO2 fell abruptly to 24 ±6 mmHg within 20–30 minutes. MPO2 during CPB was not improved by adding donor blood to the prime (n = 13). In patients undergoing cardiac surgery, UPO2 fell by 4 ± 1 mmHg and mean arterial pressure fell by 7 ± 1 mmHg during the 30 minutes before CPB. UPO2 then fell by a further 12 ± 2 mmHg during the first 30 minutes of CPB but remained relatively stable for the remaining 24 minutes of observation. Conclusions: Renal medullary hypoxia is an early event during CPB. It starts to develop even before CPB, presumably due to a pressure-dependent decrease in renal blood flow. Medullary hypoxia during CPB appears to be promoted by hypotension and is not ameliorated by increasing blood hemoglobin concentration. [ABSTRACT FROM AUTHOR]

Published
2022
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29. Dynamic responses of renal oxygenation at the onset of cardiopulmonary bypass in sheep and man

Author

Evans, Roger G, primary, Cochrane, Andrew D, additional, Hood, Sally G, additional, Iguchi, Naoya, additional, Marino, Bruno, additional, Bellomo, Rinaldo, additional, McCall, Peter R, additional, Okazaki, Nobuki, additional, Smith, Julian A, additional, Zhu, Michael ZL, additional, Ngo, Jennifer P, additional, Noe, Khin M, additional, Martin, Andrew, additional, Thrift, Amanda G, additional, Lankadeva, Yugeesh R, additional, and May, Clive N, additional

Published
2021
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30. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J‐SSCG 2020)

Author

Egi, Moritoki, primary, Ogura, Hiroshi, additional, Yatabe, Tomoaki, additional, Atagi, Kazuaki, additional, Inoue, Shigeaki, additional, Iba, Toshiaki, additional, Kakihana, Yasuyuki, additional, Kawasaki, Tatsuya, additional, Kushimoto, Shigeki, additional, Kuroda, Yasuhiro, additional, Kotani, Joji, additional, Shime, Nobuaki, additional, Taniguchi, Takumi, additional, Tsuruta, Ryosuke, additional, Doi, Kent, additional, Doi, Matsuyuki, additional, Nakada, Taka‐aki, additional, Nakane, Masaki, additional, Fujishima, Seitaro, additional, Hosokawa, Naoto, additional, Masuda, Yoshiki, additional, Matsushima, Asako, additional, Matsuda, Naoyuki, additional, Yamakawa, Kazuma, additional, Hara, Yoshitaka, additional, Sakuraya, Masaaki, additional, Ohshimo, Shinichiro, additional, Aoki, Yoshitaka, additional, Inada, Mai, additional, Umemura, Yutaka, additional, Kawai, Yusuke, additional, Kondo, Yutaka, additional, Saito, Hiroki, additional, Taito, Shunsuke, additional, Takeda, Chikashi, additional, Terayama, Takero, additional, Tohira, Hideo, additional, Hashimoto, Hideki, additional, Hayashida, Kei, additional, Hifumi, Toru, additional, Hirose, Tomoya, additional, Fukuda, Tatsuma, additional, Fujii, Tomoko, additional, Miura, Shinya, additional, Yasuda, Hideto, additional, Abe, Toshikazu, additional, Andoh, Kohkichi, additional, Iida, Yuki, additional, Ishihara, Tadashi, additional, Ide, Kentaro, additional, Ito, Kenta, additional, Ito, Yusuke, additional, Inata, Yu, additional, Utsunomiya, Akemi, additional, Unoki, Takeshi, additional, Endo, Koji, additional, Ouchi, Akira, additional, Ozaki, Masayuki, additional, Ono, Satoshi, additional, Katsura, Morihiro, additional, Kawaguchi, Atsushi, additional, Kawamura, Yusuke, additional, Kudo, Daisuke, additional, Kubo, Kenji, additional, Kurahashi, Kiyoyasu, additional, Sakuramoto, Hideaki, additional, Shimoyama, Akira, additional, Suzuki, Takeshi, additional, Sekine, Shusuke, additional, Sekino, Motohiro, additional, Takahashi, Nozomi, additional, Takahashi, Sei, additional, Takahashi, Hiroshi, additional, Tagami, Takashi, additional, Tajima, Goro, additional, Tatsumi, Hiroomi, additional, Tani, Masanori, additional, Tsuchiya, Asuka, additional, Tsutsumi, Yusuke, additional, Naito, Takaki, additional, Nagae, Masaharu, additional, Nagasawa, Ichiro, additional, Nakamura, Kensuke, additional, Nishimura, Tetsuro, additional, Nunomiya, Shin, additional, Norisue, Yasuhiro, additional, Hashimoto, Satoru, additional, Hasegawa, Daisuke, additional, Hatakeyama, Junji, additional, Hara, Naoki, additional, Higashibeppu, Naoki, additional, Furushima, Nana, additional, Furusono, Hirotaka, additional, Matsuishi, Yujiro, additional, Matsuyama, Tasuku, additional, Minematsu, Yusuke, additional, Miyashita, Ryoichi, additional, Miyatake, Yuji, additional, Moriyasu, Megumi, additional, Yamada, Toru, additional, Yamada, Hiroyuki, additional, Yamamoto, Ryo, additional, Yoshida, Takeshi, additional, Yoshida, Yuhei, additional, Yoshimura, Jumpei, additional, Yotsumoto, Ryuichi, additional, Yonekura, Hiroshi, additional, Wada, Takeshi, additional, Watanabe, Eizo, additional, Aoki, Makoto, additional, Asai, Hideki, additional, Abe, Takakuni, additional, Igarashi, Yutaka, additional, Iguchi, Naoya, additional, Ishikawa, Masami, additional, Ishimaru, Go, additional, Isokawa, Shutaro, additional, Itakura, Ryuta, additional, Imahase, Hisashi, additional, Imura, Haruki, additional, Irinoda, Takashi, additional, Uehara, Kenji, additional, Ushio, Noritaka, additional, Umegaki, Takeshi, additional, Egawa, Yuko, additional, Enomoto, Yuki, additional, Ota, Kohei, additional, Ohchi, Yoshifumi, additional, Ohno, Takanori, additional, Ohbe, Hiroyuki, additional, Oka, Kazuyuki, additional, Okada, Nobunaga, additional, Okada, Yohei, additional, Okano, Hiromu, additional, Okamoto, Jun, additional, Okuda, Hiroshi, additional, Ogura, Takayuki, additional, Onodera, Yu, additional, Oyama, Yuhta, additional, Kainuma, Motoshi, additional, Kako, Eisuke, additional, Kashiura, Masahiro, additional, Kato, Hiromi, additional, Kanaya, Akihiro, additional, Kaneko, Tadashi, additional, Kanehata, Keita, additional, Kano, Ken‐ichi, additional, Kawano, Hiroyuki, additional, Kikutani, Kazuya, additional, Kikuchi, Hitoshi, additional, Kido, Takahiro, additional, Kimura, Sho, additional, Koami, Hiroyuki, additional, Kobashi, Daisuke, additional, Saiki, Iwao, additional, Sakai, Masahito, additional, Sakamoto, Ayaka, additional, Sato, Tetsuya, additional, Shiga, Yasuhiro, additional, Shimoto, Manabu, additional, Shimoyama, Shinya, additional, Shoko, Tomohisa, additional, Sugawara, Yoh, additional, Sugita, Atsunori, additional, Suzuki, Satoshi, additional, Suzuki, Yuji, additional, Suhara, Tomohiro, additional, Sonota, Kenji, additional, Takauji, Shuhei, additional, Takashima, Kohei, additional, Takahashi, Sho, additional, Takahashi, Yoko, additional, Takeshita, Jun, additional, Tanaka, Yuuki, additional, Tampo, Akihito, additional, Tsunoyama, Taichiro, additional, Tetsuhara, Kenichi, additional, Tokunaga, Kentaro, additional, Tomioka, Yoshihiro, additional, Tomita, Kentaro, additional, Tominaga, Naoki, additional, Toyosaki, Mitsunobu, additional, Toyoda, Yukitoshi, additional, Naito, Hiromichi, additional, Nagata, Isao, additional, Nagato, Tadashi, additional, Nakamura, Yoshimi, additional, Nakamori, Yuki, additional, Nahara, Isao, additional, Naraba, Hiromu, additional, Narita, Chihiro, additional, Nishioka, Norihiro, additional, Nishimura, Tomoya, additional, Nishiyama, Kei, additional, Nomura, Tomohisa, additional, Haga, Taiki, additional, Hagiwara, Yoshihiro, additional, Hashimoto, Katsuhiko, additional, Hatachi, Takeshi, additional, Hamasaki, Toshiaki, additional, Hayashi, Takuya, additional, Hayashi, Minoru, additional, Hayamizu, Atsuki, additional, Haraguchi, Go, additional, Hirano, Yohei, additional, Fujii, Ryo, additional, Fujita, Motoki, additional, Fujimura, Naoyuki, additional, Funakoshi, Hiraku, additional, Horiguchi, Masahito, additional, Maki, Jun, additional, Masunaga, Naohisa, additional, Matsumura, Yosuke, additional, Mayumi, Takuya, additional, Minami, Keisuke, additional, Miyazaki, Yuya, additional, Miyamoto, Kazuyuki, additional, Murata, Teppei, additional, Yanai, Machi, additional, Yano, Takao, additional, Yamada, Kohei, additional, Yamada, Naoki, additional, Yamamoto, Tomonori, additional, Yoshihiro, Shodai, additional, Tanaka, Hiroshi, additional, and Nishida, Osamu, additional

Published
2021
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33. ARDS clinical practice guideline 2021

Author

Tasaka, Sadatomo, Ohshimo, Shinichiro, Takeuchi, Muneyuki, Yasuda, Hideto, Ichikado, Kazuya, Tsushima, Kenji, Egi, Moritoki, Hashimoto, Satoru, Shime, Nobuaki, Saito, Osamu, Matsumoto, Shotaro, Nango, Eishu, Okada, Yohei, Hayashi, Kenichiro, Sakuraya, Masaaki, Nakajima, Mikio, Okamori, Satoshi, Miura, Shinya, Fukuda, Tatsuma, Ishihara, Tadashi, Kamo, Tetsuro, Yatabe, Tomoaki, Norisue, Yasuhiro, Aoki, Yoshitaka, Iizuka, Yusuke, Kondo, Yutaka, Narita, Chihiro, Kawakami, Daisuke, Okano, Hiromu, Takeshita, Jun, Anan, Keisuke, Okazaki, Satoru Robert, Taito, Shunsuke, Hayashi, Takuya, Mayumi, Takuya, Terayama, Takero, Kubota, Yoshifumi, Abe, Yoshinobu, Iwasaki, Yudai, Kishihara, Yuki, Kataoka, Jun, Nishimura, Tetsuro, Yonekura, Hiroshi, Ando, Koichi, Yoshida, Takuo, Masuyama, Tomoyuki, Sanui, Masamitsu, Nakashima, Takuro, Masunaga, Aiko, Tanaka, Aiko, Inoue, Akihiko, Higashi, Akiko, Tanikawa, Atsushi, Ujiro, Atsushi, Takayama, Chihiro, Kasugai, Daisuke, Kawakami, Daisuke, Ueno, Daisuke, Satoh, Daizoh, Kai, Shinichi, Ota, Kohei, Hagiwara, Yoshihiro, Hamaguchi, Jun, Fujii, Ryo, Hongo, Takashi, Kishihara, Yuki, Masunaga, Naohisa, Yamamoto, Ryohei, Okazaki, Satoru Robert, Uchimido, Ryo, Terayama, Tetsuro, Hokari, Satoshi, Sakamoto, Hitoshi, Dongli, Nakataki, Emiko, Tabata, Erina, Okazawa, Seisuke, Kotajima, Futoshi, Ishimaru, Go, Hoshino, Haruhiko, Yoshida, Hideki, Iwai, Hidetaka, Nakagawa, Hiroaki, Sugimura, Hiroko, Narumiya, Hiromichi, Okano, Hiromu, Nakamura, Hiroshi, Sugimoto, Hiroshi, Hashimoto, Hiroyuki, Ito, Hiroyuki, Dote, Hisashi, Imahase, Hisashi, Sato, Hitoshi, Katsurada, Masahiro, Osawa, Ichiro, Kamei, Jun, Maki, Jun, Sugihara, Jun, Takeshita, Jun, Fujimoto, Junichi, Ishikawa, Junichi, Kosaka, Junko, Shibata, Junpei, Hashimoto, Katsuhiko, Nakano, Yasushi, Kikuyama, Kazuki, Shimizu, Kazushige, Okada, Kazuya, Kawano, Keishi, Anan, Keisuke, Ota, Keisuke, Kano, Ken-ichi, Asano, Kengo, Hondo, Kenichi, Ishii, Kenji, Fujita, Kensuke, Ogawa, Kenta, Ito, Kentaro, Tokunaga, Kentaro, Ishii, Kenzo, Kusumoto, Kohei, Takimoto, Kohei, Yamada, Kohei, Naito, Koichi, Yamashita, Koichi, Yoshinaga, Koichi, Yamauchi, Kota, Murata, Maki, Konda, Makiko, Hamamoto, Manabu, Aga, Masaharu, Kashiura, Masahiro, Ishikawa, Masami, Ozaki, Masayuki, Kono, Michihiko, Kyo, Michihito, Hayashi, Minoru, Abe, Mitsuhiro, Sato, Mitsunori, Sakai, Mizu, Kainuma, Motoshi, Tominaga, Naoki, Iguchi, Naoya, Nakagawa, Natsuki, Aoki, Nobumasa, Nishioka, Norihiro, Miyashita, Norihisa, Seki, Nozomu, Ikebe, Ryo, Imai, Ryosuke, Tate, Ryota, Sato, Ryuhei, Miyakawa, Sachiko, Kazuma, Satoshi, Nakano, Satoshi, Tetsumoto, Satoshi, Yoshimura, Satoshi, Yoshitake, Shigenori, Hoshi, Shin-etsu, Ohki, Shingo, Sato, Shintaro, Yoshihiro, Shodai, Ihara, Shoichi, Yamamoto, Shota, Koide, Shunichi, Kimata, Shunsuke, Saito, Shunsuke, Yasuo, Shunsuke, Sekine, Shusuke, Mimuro, Soichiro, Wada, Soichiro, Sugimura, Sosuke, Ishihara, Tadashi, Kaneko, Tadashi, Nagato, Tadashi, Maruhashi, Takaaki, Tamura, Takahiro, Ohno, Takanori, Ichiyama, Takashi, Niwa, Takashi, Ueji, Takashi, Ogura, Takayuki, Kawasaki, Takeshi, Tanaka, Takeshi, Umegaki, Takeshi, Furukawa, Taku, Omura, Taku, Nagao, Takumi, Mayumi, Takuya, Taniguchi, Takuya, Yoshida, Takuya, Shimatani, Tatsutoshi, Murata, Teppei, Sato, Tetsuya, Sawamoto, Tohru, Koukei, Yoshifumi, Takehara, Tomohiro, Ueda, Tomomi, Katsuta, Tomoya, Nishino, Tomoya, Yokoyama, Toshiki, Higashijima, Ushio, Iwanaga, Wataru, Inoue, Yasushi, Iwashita, Yoshiaki, Yamada, Yoshie, Kubota, Yoshifumi, Suido, Yoshihiro, Tomioka, Yoshihiro, Fujimoto, Yoshihisa, Fujita, Yoshihito, Yamaguchi, Yoshikazu, Nakamura, Yoshimi, Abe, Yoshinobu, Eguchi, Yoshitomo, Oshima, Yoshiyasu, Fukuda, Yosuke, Iwasaki, Yudai, Yasufuku, Yuichi, Shono, Yuji, Nakatani, Yuka, Nakamori, Yuki, Ito, Yukie, Tanabe, Yuko, Nagamine, Yusuke, Nakamura, Yuta, and Kurihara, Yutaro

Abstract

The joint committee of the Japanese Society of Intensive Care Medicine/Japanese Respiratory Society/Japanese Society of Respiratory Care Medicine on ARDS Clinical Practice Guideline has created and released the ARDS Clinical Practice Guideline 2021.

Published
2022
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34. Effect of Furosemide on Urinary Oxygenation in Patients with Septic Shock

Author

Osawa, Eduardo Atsushi, Cutuli, Salvatore Lucio, Bitker, Laurent, Canet, Emmanuel, Cioccari, Luca, Iguchi, Naoya, Lankadeva, Yugeesh R, Eastwood, Glenn M, Evans, Roger G, May, Clive N, and Bellomo, Rinaldo

Subjects
610 Medicine & health
Abstract

BACKGROUND Renal medullary hypoxia precedes the development of acute kidney injury in experimental sepsis and can now be assessed by continuous measurement of urinary oxygen tension (PuO2). OBJECTIVES We aimed to test if PuO2 measurements in patients with septic shock would be similar to those shown in experimental sepsis and would detect changes induced by the administration of furosemide. METHOD Pilot prospective observational cohort study in a tertiary intensive care unit (ICU). Seven adult patients with septic shock admitted to ICU had PuO2 measurements recorded minutely. There were 29 episodes of intravenous furosemide (20 mg n = 19; 40 mg n = 10). RESULTS The median pre-furosemide PuO2 was low at 21.2 mm Hg (interquartile range [IQR] 17.73-24.86) and increased to 26 mm Hg (IQR 20.27-29.95) at 20 min (p < 0.01), to 27.5 mm Hg (IQR 24.06-33.18) at 40 min (p < 0.01) and to 28.5 mm Hg (IQR 22.65-31.03) at 60 min (p < 0.01). The increase in PuO2 was greater in episodes with a diuretic response >2 mL/kg/h than during episodes without such a response (p < 0.01). CONCLUSIONS PuO2 measurements in patients are reflective of the low values reported in experimental models of sepsis. PuO2 values increased following furosemide administration with a response independently associated with greater diuresis.

Published
2019
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39. Reversal of renal tissue hypoxia during experimental cardiopulmonary bypass in sheep by increased pump flow and arterial pressure.

Author

Lankadeva, Yugeesh R., Evans, Roger G., Cochrane, Andrew D., Marino, Bruno, Hood, Sally G., McCall, Peter R., Iguchi, Naoya, Bellomo, Rinaldo, and May, Clive N.

Subjects
CARDIOPULMONARY bypass, ACUTE kidney failure, PULSATILE flow, BLOOD flow, SHEEP
Abstract

Aim: Renal tissue hypoxia during cardiopulmonary bypass could contribute to the pathophysiology of acute kidney injury. We tested whether renal tissue hypoxia can be alleviated during cardiopulmonary bypass by the combined increase in target pump flow and mean arterial pressure. Methods: Cardiopulmonary bypass was established in eight instrumented sheep under isoflurane anaesthesia, at a target continuous pump flow of 80 mL·kg−1 min−1 and mean arterial pressure of 65 mmHg. We then tested the effects of simultaneously increasing target pump flow to 104 mL·kg−1 min−1 and mean arterial pressure to 80 mmHg with metaraminol (total dose 0.25‐3.75 mg). We also tested the effects of transitioning from continuous flow to partially pulsatile flow (pulse pressure ~15 mmHg). Results: Compared with conscious sheep, at the lower target pump flow and mean arterial pressure, cardiopulmonary bypass was accompanied by reduced renal blood flow (6.8 ± 1.2 to 1.95 ± 0.76 mL·min−1 kg−1) and renal oxygen delivery (0.91 ± 0.18 to 0.24 ± 0.11 mL·O2 min−1 kg−1). There were profound reductions in cortical oxygen tension (PO2) (33 ± 13 to 6 ± 6 mmHg) and medullary PO2 (31 ± 12 to 8 ± 8 mmHg). Increasing target pump flow and mean arterial pressure increased renal blood flow (to 2.6 ± 1.0 mL·min−1 kg−1) and renal oxygen delivery (to 0.32 ± 0.13 mL·O2 min−1kg−1) and returned cortical PO2 to 58 ± 60 mmHg and medullary PO2 to 28 ± 16 mmHg; levels similar to those of conscious sheep. Partially pulsatile pump flow had no significant effects on renal perfusion or oxygenation. Conclusions: Renal hypoxia during experimental CPB can be corrected by increasing target pump flow and mean arterial pressure within a clinically feasible range. [ABSTRACT FROM AUTHOR]

Published
2021
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40. Effect of Furosemide on Urinary Oxygenation in Patients with Septic Shock

Author

Osawa, Eduardo Atsushi, primary, Cutuli, Salvatore Lucio, additional, Bitker, Laurent, additional, Canet, Emmanuel, additional, Cioccari, Luca, additional, Iguchi, Naoya, additional, Lankadeva, Yugeesh R., additional, Eastwood, Glenn M., additional, Evans, Roger G., additional, May, Clive N., additional, and Bellomo, Rinaldo, additional

Published
2019
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