14 results on '"Imola, Manuela"'
Search Results
2. Viral Population Heterogeneity and Fluctuating Mutational Pattern during a Persistent SARS-CoV-2 Infection in an Immunocompromised Patient
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Brandolini, Martina, primary, Zannoli, Silvia, additional, Gatti, Giulia, additional, Arfilli, Valentina, additional, Cricca, Monica, additional, Dirani, Giorgio, additional, Denicolò, Agnese, additional, Semprini, Simona, additional, Grumiro, Laura, additional, Imola, Manuela, additional, Larne, Damiano, additional, Marino, Maria Michela, additional, Manera, Martina, additional, Mancini, Andrea, additional, Taddei, Francesca, additional, Zagarrigo, Manuel, additional, Biagetti, Carlo, additional, and Sambri, Vittorio, additional
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- 2023
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3. Is Lipoplatinum Monotherapy an Active Alternative in Second Line Treatment of Metastatic Non–Small Cell Lung Cancer? A Phase II Trial
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Ravaioli, Alberto, Fantini, Manuela, Drudi, Fabrizio, Papi, Maximilian, Pasquini, Enzo, Marangolo, Maurizio, Zoli, Wainer, Panzini, Ilaria, Rudnas, Britt, VL Nicoletti, Stefania, Possenti, Cinzia, Tamburini, Emiliano, Gianni, Lorenzo, Imola, Manuela, Bonetti, Andrea, editor, Leone, Roberto, editor, Muggia, Franco M., editor, and Howell, Stephen B., editor
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- 2009
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4. Factors affecting successful mobilization with plerixafor: an Italian prospective survey in 215 patients with multiple myeloma and lymphoma
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Lanza, Francesco, Lemoli, Roberto M., Olivieri, Attilio, Laszlo, Daniele, Martino, Massimo, Specchia, Giorgina, Pavone, Vincenzo, Imola, Manuela, Pasini, Annalisa, Milone, Giuseppe, Scortechini, Ilaria, Todisco, Elisabetta, Guggiari, Elena, Cascavilla, Nicola, Martinelli, Giovanni, Rambaldi, Alessandro, and Bosi, Alberto
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- 2014
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5. Incidence, Risk Factors and Outcome of Pre-engraftment Gram-Negative Bacteremia After Allogeneic and Autologous Hematopoietic Stem Cell Transplantation: An Italian Prospective Multicenter Survey
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Girmenia, Corrado, Bertaina, Alice, Piciocchi, Alfonso, Perruccio, Katia, Algarotti, Alessandra, Busca, Alessandro, Cattaneo, Chiara, Raiola, Anna Maria, Guidi, Stefano, Iori, Anna Paola, Candoni, Anna, Irrera, Giuseppe, Milone, Giuseppe, Marcacci, Giampaolo, Scimè, Rosanna, Musso, Maurizio, Cudillo, Laura, Sica, Simona, Castagna, Luca, Corradini, Paolo, Marchesi, Francesco, Pastore, Domenico, Alessandrino, Emilio Paolo, Annaloro, Claudio, Ciceri, Fabio, Santarone, Stella, Nassi, Luca, Farina, Claudio, Viscoli, Claudio, Rossolini, Gian Maria, Bonifazi, Francesca, Rambaldi, Alessandro, Capria, Saveria, Bertaina, A., Mastronuzzi, Angela, Pagliara, Daria, Bernaschi, Paola, Amico, Lucia, Carotti, Alessandra, Mencacci, Antonella, Busca, A., Bruno, Benedetto, Costa, Cristina, Passi, Angela, Ravizzola, Giuseppe, Angelucci, Emanuele, Marchese, Anna, Pecile, Patrizia, Candoni, A., Ventura, Giovanna, Fanin, Renato, Scarparo, Claudio, Barbaro, Angelo, Milone, G., Leotta, Salvatore, Marchese, Anna Elisa, Marcacci, G., Becchimanzi, Cristina, Donnarumma, Daniela, Tringali, Stefania, Baldi, Maria Teresa, Scalone, Renato, Cudillo, L., Picardi, Alessandra, Arcese, William, Fontana, Carla, Sica, S., Giammarco, Sabrina, Spanu, Teresa, Castagna, L., Crocchiolo, Roberto, Casari, Erminia, Mussetti, Alberto, Conte, Eutilia, Ensoli, Fabrizio, Miragliotta, Giuseppe, Marone, Piero, Arghittu, Milena, Greco, Raffaella, Forcina, Alessandra, Chichero, Paola, Santarone, S., Di Bartolomeo, Paolo, Fazii, Paolo, Kroumova, Vesselina, Decembrino, Nunzia, Zecca, Marco, Pisapia, Giovanni, Palazzo, Giulia, Lanino, Edoardo, Faraci, Maura, Castagnola, Elio, Bandettini, Roberto, Pastano, Rocco, Sammassimo, Simona, Passerini, Rita, Stefani, Piero Maria, Gherlinzoni, Filippo, Rigoli, Roberto, Prezioso, Lucia, Cambò, Benedetta, Calderaro, Adriana, Carella, Angelo Michele, Cascavilla, Nicola, Labonia, Maria Teresa, Celeghini, Ivana, Mordini, Nicola, Piana, Federica, Vacca, Adriana, Sanna, Marco, Podda, Giovanni, Corsetti, Maria Teresa, Rocchetti, Andrea, Cilloni, Daniela, De Gobbi, Marco, Bianco, Ornella, Fagioli, Franca, Carraro, Francesca, De Intinis, Gianfranco, Severino, Alessandro, Proia, Anna, Parisi, Gabriella, Vallisa, Daniele, Confalonieri, Massimo, Russo, Domenico, Malagola, Michele, Galieni, Piero, Falcioni, Sadia, Travaglini, Valeria, Raimondi, Roberto, Borghero, Carlo, Pavan, Giacomina, Prete, Arcangelo, Belotti, Tamara, Ambretti, Simone, Imola, Manuela, Mianulli, Anna Maria, Pedna, Maria Federica, Cesaro, Simone, Lo Cascio, Giuliana, Ferrari, Antonella, Piedimonte, Monica, Santino, Iolanda, Calandrelli, Monica, Olivieri, Attilio, Orecchioni, Francesca, Mirabile, Milena, Centurioni, Riccardo, Gironacci, Luciana, Caravelli, Daniela, Gallo, Susanna, De Filippi, Marco, Cupelli, Luca, Dentamaro, Teresa, Falco, Silvana, Eugenio, Ospedale S, Marotta, Serena, Risitano, Antonio, Lula, Dora, Musto, Pellegrino, Pietrantuono, Giuseppe, Traficante, Antonio, Cerchiara, Elisabetta, Tirindelli, Maria Cristina, Dicuonzo, Giordano, Chierichini, Anna, Anaclerico, Barbara, Placanica, Paola, Girmenia, C, Bertaina, A, Piciocchi, A, Perruccio, K, Algarotti, A, Busca, A, Cattaneo, C, Raiola, Am, Guidi, S, Iori, Ap, Candoni, A, Irrera, G, Milone, G, Marcacci, G, Scimè, R, Musso, M, Cudillo, L, Sica, S, Castagna, L, Corradini, P, Marchesi, F, Pastore, D, Alessandrino, Ep, Annaloro, C, Ciceri, F, Santarone, S, Nassi, L, Farina, C, Viscoli, C, Rossolini, Gm, Bonifazi, F, Rambaldi, A, for the Gruppo Italiano Trapianto di Midollo Osseo, (GITMO), Associazione Microbiologi Clinici Italiani, (AMCLI), Girmenia, Corrado, Bertaina, Alice, Piciocchi, Alfonso, Perruccio, Katia, Algarotti, Alessandra, Busca, Alessandro, Cattaneo, Chiara, Raiola, Anna Maria, Guidi, Stefano, Iori, Anna Paola, Candoni, Anna, Irrera, Giuseppe, Milone, G., Marcacci, Giampaolo, Scimè, Rosanna, Musso, Maurizio, Cudillo, Laura, Sica, Simona, Castagna, Luca, Corradini, Paolo, Marchesi, Francesco, Pastore, Domenico, Alessandrino, Emilio Paolo, Annaloro, Claudio, Ciceri, Fabio, Santarone, Stella, Nassi, Luca, Farina, Claudio, Viscoli, Claudio, Rossolini, Gian Maria, Bonifazi, Francesca, Rambaldi, Alessandro, Capria, Saveria, Bertaina, A., Mastronuzzi, Angela, Pagliara, Daria, Bernaschi, Paola, Amico, Lucia, Carotti, Alessandra, Mencacci, Antonella, Busca, A., Bruno, Benedetto, Costa, Cristina, Passi, Angela, Ravizzola, Giuseppe, Angelucci, Emanuele, Marchese, Anna, Pecile, Patrizia, Candoni, A., Ventura, Giovanna, Fanin, Renato, Scarparo, Claudio, Barbaro, Angelo, Leotta, Salvatore, Marchese, Anna Elisa, Marcacci, G., Becchimanzi, Cristina, Donnarumma, Daniela, Tringali, Stefania, Baldi, Maria Teresa, Scalone, Renato, Cudillo, L., Picardi, Alessandra, Arcese, William, Fontana, Carla, Sica, S., Giammarco, Sabrina, Spanu, Teresa, Castagna, L., Crocchiolo, Roberto, Casari, Erminia, Mussetti, Alberto, Conte, Eutilia, Ensoli, Fabrizio, Miragliotta, Giuseppe, Marone, Piero, Arghittu, Milena, Greco, Raffaella, Forcina, Alessandra, Chichero, Paola, Santarone, S., Di Bartolomeo, Paolo, Fazii, Paolo, Kroumova, Vesselina, Decembrino, Nunzia, Zecca, Marco, Pisapia, Giovanni, Palazzo, Giulia, Lanino, Edoardo, Faraci, Maura, Castagnola, Elio, Bandettini, Roberto, Pastano, Rocco, Sammassimo, Simona, Passerini, Rita, Stefani, Piero Maria, Gherlinzoni, Filippo, Rigoli, Roberto, Prezioso, Lucia, Cambò, Benedetta, Calderaro, Adriana, Carella, Angelo Michele, Cascavilla, Nicola, Labonia, Maria Teresa, Celeghini, Ivana, Mordini, Nicola, Piana, Federica, Vacca, Adriana, Sanna, Marco, Podda, Giovanni, Corsetti, Maria Teresa, Rocchetti, Andrea, Cilloni, Daniela, De Gobbi, Marco, Bianco, Ornella, Fagioli, Franca, Carraro, Francesca, De Intinis, Gianfranco, Severino, Alessandro, Proia, Anna, Parisi, Gabriella, Vallisa, Daniele, Confalonieri, Massimo, Russo, Domenico, Malagola, Michele, Galieni, Piero, Falcioni, Sadia, Travaglini, Valeria, Raimondi, Roberto, Borghero, Carlo, Pavan, Giacomina, Prete, Arcangelo, Belotti, Tamara, Ambretti, Simone, Imola, Manuela, Mianulli, Anna Maria, Pedna, Maria Federica, Cesaro, Simone, Lo Cascio, Giuliana, Ferrari, Antonella, Piedimonte, Monica, Santino, Iolanda, Calandrelli, Monica, Olivieri, Attilio, Orecchioni, Francesca, Mirabile, Milena, Centurioni, Riccardo, Gironacci, Luciana, Caravelli, Daniela, Gallo, Susanna, De Filippi, Marco, Cupelli, Luca, Dentamaro, Teresa, Falco, Silvana, Eugenio, Ospedale S, Marotta, Serena, Risitano, Antonio, Lula, Dora, Musto, Pellegrino, Pietrantuono, Giuseppe, Traficante, Antonio, Cerchiara, Elisabetta, Tirindelli, Maria Cristina, Dicuonzo, Giordano, Chierichini, Anna, Anaclerico, Barbara, and Placanica, Paola
- Subjects
0301 basic medicine ,Male ,Transplantation Conditioning ,Drug Resistance ,Bacteremia ,0302 clinical medicine ,epidemiology ,Gram negative bacteremia ,multidrug resistance ,stem cell transplant ,survival ,Risk Factors ,Drug Resistance, Multiple, Bacterial ,Epidemiology ,Medicine ,Age Factor ,Prospective Studies ,Prospective cohort study ,Child ,Transplantation, Homologou ,education.field_of_study ,Incidence (epidemiology) ,Incidence ,Bacterial ,Age Factors ,Hematopoietic Stem Cell Transplantation ,Middle Aged ,Transplantation, Autologou ,surgical procedures, operative ,Infectious Diseases ,Italy ,Child, Preschool ,Female ,medicine.symptom ,Multiple ,Autologous ,Human ,Homologous ,Microbiology (medical) ,Adult ,medicine.medical_specialty ,Adolescent ,030106 microbiology ,Population ,Transplantation, Autologous ,03 medical and health sciences ,Young Adult ,Internal medicine ,Gram-Negative Bacteria ,Gram-Negative Bacterial Infection ,Escherichia coli ,Humans ,Transplantation, Homologous ,Preschool ,education ,Aged ,Gram-Negative Bacterial Infections ,Infant ,Transplantation ,business.industry ,Risk Factor ,medicine.disease ,Prospective Studie ,Carriage ,Otitis ,business ,Settore MED/15 - Malattie del Sangue ,030215 immunology - Abstract
Background Gram-negative bacteremia (GNB) is a major cause of illness and death after hematopoietic stem cell transplantation (HSCT), and updated epidemiological investigation is advisable. Methods We prospectively evaluated the epidemiology of pre-engraftment GNB in 1118 allogeneic HSCTs (allo-HSCTs) and 1625 autologous HSCTs (auto-HSCTs) among 54 transplant centers during 2014 (SIGNB-GITMO-AMCLI study). Using logistic regression methods. we identified risk factors for GNB and evaluated the impact of GNB on the 4-month overall-survival after transplant. Results The cumulative incidence of pre-engraftment GNB was 17.3% in allo-HSCT and 9% in auto-HSCT. Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa were the most common isolates. By multivariate analysis, variables associated with GNB were a diagnosis of acute leukemia, a transplant from a HLA-mismatched donor and from cord blood, older age, and duration of severe neutropenia in allo-HSCT, and a diagnosis of lymphoma, older age, and no antibacterial prophylaxis in auto-HSCT. A pretransplant infection by a resistant pathogen was significantly associated with an increased risk of posttransplant infection by the same microorganism in allo-HSCT. Colonization by resistant gram-negative bacteria was significantly associated with an increased rate of infection by the same pathogen in both transplant procedures. GNB was independently associated with increased mortality at 4 months both in allo-HSCT (hazard ratio, 2.13; 95% confidence interval, 1.45–3.13; P Conclusions Pre-engraftment GNB is an independent factor associated with increased mortality rate at 4 months after auto-HSCT and allo-HSCT. Previous infectious history and colonization monitoring represent major indicators of GNB. Clinical Trials registration NCT02088840.
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- 2017
6. ADJUVANT CHEMOTHERAPY IN GASTRIC CANCER: METAANALYSIS OF 17 RANDOMIZED CLINICAL TRIALS.
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Panzini, Ilaria, Gianni, Lorenzo, Tassinari, Davide, Arcangeli, Valentina, Drudi, Giuliana, Venturini, Barbara, Nocelli, Manuela, Imola, Manuela, and Ravaioli, Alberto
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- 2000
7. Multiple Myeloma and Renal Failure
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Tosi, Patrizia, primary, Imola, Manuela, additional, Mianulli, Anna Maria, additional, Tomassetti, Simona, additional, Molinari, Annalia, additional, Mangianti, Serena, additional, Ratta, Marina, additional, Merli, Anna, additional, and Polli, Valentina, additional
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- 2015
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8. Factors affecting successful mobilization with plerixafor: an Italian prospective survey in 215 patients with multiple myeloma and lymphoma
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Lanza, Francesco, primary, Lemoli, Roberto M., additional, Olivieri, Attilio, additional, Laszlo, Daniele, additional, Martino, Massimo, additional, Specchia, Giorgina, additional, Pavone, Vincenzo, additional, Imola, Manuela, additional, Pasini, Annalisa, additional, Milone, Giuseppe, additional, Scortechini, Ilaria, additional, Todisco, Elisabetta, additional, Guggiari, Elena, additional, Cascavilla, Nicola, additional, Martinelli, Giovanni, additional, Rambaldi, Alessandro, additional, and Bosi, Alberto, additional
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- 2013
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9. UPDATE ON THE ROLE OF AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION IN MULTIPLE MYELOMA
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Tosi, Patrizia, primary, Imola, Manuela, primary, Maria, Mianulli Anna, primary, Tomassetti, Simona, primary, Merli, Anna, primary, Molinari, Annalia, primary, Mangianti, Serena, primary, Ratta, Marina, primary, Isidori, Alessandro, primary, and Visani, Giuseppe, primary
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- 2012
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10. Long Term Efficacy of Percutaneous Vertebroplasty in Multiple Myeloma (MM) Patients: Experience of the “Gruppo Ematologico Di Romagna” (GER)
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Tosi, Patrizia, primary, Molinari, Annalia, additional, Sintini, Michele, additional, Merli, Anna, additional, Ceccolini, Michela, additional, Imola, Manuela, additional, Savini, Paolo, additional, Pasini, Silvana, additional, Mianulli, Anna M, additional, Castagnari, Barbara, additional, Fattori, Pier P, additional, Martinelli, Giovanni, additional, and Zaccaria, Alfonso, additional
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- 2011
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11. Carboplatin and Gemcitabine in the Palliative Treatment of Stage IV Non-Small Cell Lung Cancer: Definitive Results of a Phase II Trial
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Tassinari, Davide, primary, Fochessati, Francesca, additional, Arcangeli, Valentina, additional, Sartori, Sergio, additional, Agostini, Vanessa, additional, Fantini, Manuela, additional, Genestreti, Giovenzio, additional, Grassia, Sergio, additional, Ioli, Giorgio, additional, Imola, Manuela, additional, Iorio, Domenico, additional, Mianulli, Anna Maria, additional, Monticelli, Giancarla, additional, Oliverio, Giovanni, additional, Panzini, Ilaria, additional, Papi, Maximilian, additional, Poggi, Barbara, additional, Polselli, Antonio, additional, Pulini, Stefano, additional, Tamburini, Emiliano, additional, Fattori, Pier Paolo, additional, and Ravaioli, Alberto, additional
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- 2004
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12. Lenalidomide in Combination with Dexamethasone in Elderly Patients with Advanced, Relapsed or Refractory Multiple Myeloma and Renal Failure.
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Tosi, Patrizia, Gamberi, Barbara, Castagnari, Barbara, Molinari, Anna Lia, Savini, Paolo, Ceccolini, Michela, Tani, Monica, Merli, Anna, Imola, Manuela, Mianulli, Anna Maria, Cellini, Claudia, Tomassetti, Simona, Merli, Francesco, Fattori, Pierpaolo, and Zaccaria, Alfonso
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HEALTH outcome assessment ,TREATMENT of diseases in older people ,COMORBIDITY ,MULTIPLE myeloma ,DEXAMETHASONE ,PREGNANE ,PATIENTS - Abstract
Salvage therapy of elderly patients with advanced, relapsed and refractory multiple myeloma (MM) is often limited by poor marrow reserve and multi-organ impairment. In particular, renal failure occurs in up to 50% of such patients, and this can potentially limit the therapeutic options. Both thalidomide and bortezomib have proven effective in these patients, with an acceptable toxicity, while, in clinical practice, lenalidomide is generally not considered a first-choice drug for MM patients with renal failure as early reports showed an increased hematological toxicity unless appropriate dose reduction is applied. Aim of this study was a retrospective evaluation of the efficacy of the combination Lenalidomide + Dexamethasone in a population of elderly MM patients treated in 5 Italian Centers. The study included 20 consecutive MM patients (9 M, 11 F, median age 76.5 years) with relapsed (N= 6) or refractory (N=13) MM and moderate to severe renal failure, defined as creatinine clearance (Cr Cl) < 50ml/min. Four patients were undergoing hemodyalisis at study entry. 85 % of the patients had been previously treated with bortezomib-containing regimens. Lenalidomide dose was adjusted according to renal function and patients clinical conditions Median treatment duration was 16 months (1-22), therapy was interrupted after 1 21-day cycle in 2 patients. Grade III-IV neutropenia was observed in 7 patients (35%); grade III-IV non hematological toxicity was recorded in 3 cases (28%). A > partial response was observed in 8 patients (40%), 1 of whom obtained a VGPR; 4 additional patients achieved a minor response. Median response duration was 16 months (range 2-19+ months). A complete and partial renal response was obtained in 4 and 3 patients, respectively, all of them were responsive to Lenalidomide-dexamethasone According to our data, LEN+DEX has shown efficacy and acceptable toxicity in this population of elderly patients with advanced MM and renal failure [ABSTRACT FROM AUTHOR]
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- 2013
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13. [Chemotherapy in extended small-cell lung cancer. Retrospective analysis of two different series of patients treated with carboplatin and etoposide or ciclophosphamide-epidoxorubicin and etoposide].
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Tassinari D, Genestreti G, Pasquini E, Fantini M, Poggi B, Tamburini E, Papi M, Ioli G, Oliverio G, Fochessati F, Arcangeli V, Agostini V, Mianulli AM, Imola M, Fattori PP, and Ravaioli A
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- Adult, Aged, Aged, 80 and over, Carboplatin administration & dosage, Cisplatin therapeutic use, Cyclophosphamide therapeutic use, Epirubicin therapeutic use, Etoposide administration & dosage, Etoposide therapeutic use, Female, Humans, Male, Middle Aged, Retrospective Studies, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Carcinoma, Small Cell drug therapy, Lung Neoplasms drug therapy
- Abstract
Although cisplatin and etoposide seem to represent the treatment of choice in Small-Cell Lung Cancer, a lot of data exist in literature supporting both the use of anthracycline-containing regimens and the use of alternating regimens where platinum-containing regimens and anthracycline-containing regimens are alternatively used as first line in the same patient. In our paper we review the outcomes of two different series of patients treated with ciclophosphamide-epidoxorubicin-etoposide (CEVP16) or carboplatin-etoposide (CBE) for extended Small-Cell Lung Cancer. Sixty-three patients (53.4%) were treated with CEVP16 and 55 patients (46.6%) with CBE. Response Rate (complete plus partial responses) was greater in patients treated with CEVP16 (49.2%) when compared with the response rate in patients treated with CBE (30.9%) (p=0.04 using the Chi-Square test); no differences were observed in the median time to progression (235 vs 199 days, using the Log-Rank test). Overall survival was greater in the CEVP16 group when compared with the CBE one (281 vs 208 days and 35.6% vs 16.3% of patients alive after 2 years of follow up for CEVP16 and CBE respectively, p=0.02 using the Log-Rank test). Although our data present all the methodological limits of the "case-series", it is interesting to observe how an anthracycline-containing regimen seems to be more effective than a platinum-containing one and how it could still play a role in the treatment of extended Small-Cell Lung Cancer.
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- 2005
14. Adjuvant chemotherapy in gastric cancer: a meta-analysis of randomized trials and a comparison with previous meta-analyses.
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Panzini I, Gianni L, Fattori PP, Tassinari D, Imola M, Fabbri P, Arcangeli V, Drudi G, Canuti D, Fochessati F, and Ravaioli A
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- Chemotherapy, Adjuvant, Humans, Immunotherapy, Odds Ratio, Prognosis, Randomized Controlled Trials as Topic, Stomach Neoplasms mortality, Stomach Neoplasms surgery, Survival Rate, Treatment Outcome, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Stomach Neoplasms drug therapy
- Abstract
Aims and Background: Up to now adjuvant chemotherapy after curative resection for gastric cancer (GC) has been considered an experimental approach. The results of existing phase III randomized trials comparing chemotherapy with control after surgery are controversial. Three meta-analyses have been published in recent years. It is likely that each of them presents a theoretical bias, mainly as regards the inclusion criteria of the trials. In this article we re-examine this potential bias, highlighting the differences between the present and past meta-analyses on adjuvant chemotherapy for GC., Methods: Only randomized controlled clinical trials comparing systemic adjuvant chemotherapy with control after radical resection of GC were eligible. Total mortality was assessed as outcome measure of the treatment effect and a pooled odds ratio was calculated using the Peto-Mantel-Haenszel method., Results: After the selection process 17 papers (18 comparisons) proved eligible for inclusion in the meta-analysis with a total of 3118 patients, of whom 1546 randomized to the treatment arms and 1572 to the control arms; 762 and 871 deaths occurred in the treatment and control arms, respectively. Statistical analysis suggests an absence of significant heterogeneity between the trials and a significant advantage in survival for adjuvant chemotherapy (pooled odds ratio, 0.72, 95% Cl, 0.62-0.84)., Conclusions: Our meta-analysis would seem to indicate that adjuvant chemotherapy results in a significant survival advantage in patients with GC. However, this observation undoubtedly requires confirmation in large randomized controlled trials including cisplatin before adjuvant chemotherapy after curative resection for GC can be proposed for use in clinical practice.
- Published
- 2002
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