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1. AMPK Profiling in Rodent and Human Pancreatic Beta-Cells under Nutrient-Rich Metabolic Stress.

2. Functional proteasome complex is required for turnover of islet amyloid polypeptide in pancreatic β-cells.

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3. IRE1-XBP1 pathway regulates oxidative proinsulin folding in pancreatic β cells.

4. Pyruvate kinase M1 interacts with A-Raf and inhibits endoplasmic reticulum stress-induced apoptosis by activating MEK1/ERK pathway in mouse insulinoma cells.

5. Transduction of PEP-1-heme oxygenase-1 into insulin-producing INS-1 cells protects them against cytokine-induced cell death.

6. Calcium/calmodulin-dependent serine protein kinase is involved in exendin-4-induced insulin secretion in INS-1 cells.

7. PGP 9.5 immunocytochemical staining for pancreatic endocrine tumors.

8. Activated mTOR/P70S6K signaling pathway is involved in insulinoma tumorigenesis.

9. Group VIB Phospholipase A(2) promotes proliferation of INS-1 insulinoma cells and attenuates lipid peroxidation and apoptosis induced by inflammatory cytokines and oxidant agents.

10. The gene encoding cyclooxygenase-2 is regulated by IL-1β and prostaglandins in 832/13 rat insulinoma cells.

11. Chronic reduction of the cytosolic or mitochondrial NAD(P)-malic enzyme does not affect insulin secretion in a rat insulinoma cell line.

12. Transcripts of calcium/calmodulin-dependent kinases are changed after forskolin- or IBMX-induced insulin secretion due to melatonin treatment of rat insulinoma beta-cells (INS-1).

13. Phosphoenolpyruvate cycling via mitochondrial phosphoenolpyruvate carboxykinase links anaplerosis and mitochondrial GTP with insulin secretion.

14. Resistin induces rat insulinoma cell RINm5F apoptosis.

15. AMP-activated protein kinase and pancreatic/duodenal homeobox-1 involved in insulin secretion under high leucine exposure in rat insulinoma beta-cells.

16. Investigating the roles of mitochondrial and cytosolic malic enzyme in insulin secretion.

17. The MAPK kinase kinase-1 is essential for stress-induced pancreatic islet cell death.

18. Inhibition of SH2-domain containing inositol phosphatase 2 (SHIP2) in insulin producing INS1E cells improves insulin signal transduction and induces proliferation.

19. The group VIA calcium-independent phospholipase A2 participates in ER stress-induced INS-1 insulinoma cell apoptosis by promoting ceramide generation via hydrolysis of sphingomyelins by neutral sphingomyelinase.

20. Glucose regulated proteins 78 protects insulinoma cells (NIT-1) from death induced by streptozotocin, cytokines or cytotoxic T lymphocytes.

21. The aminoguanidine carboxylate BVT.12777 activates ATP-sensitive K+ channels in the rat insulinoma cell line, CRI-G1.

22. Histidine decarboxylase expression in pancreatic endocrine cells and related tumors.

23. Cellular proliferative fraction measured with topoisomerase IIalpha predicts malignancy in endocrine pancreatic tumors.

24. Pancreatic islets and insulinoma cells express a novel isoform of group VIA phospholipase A2 (iPLA2 beta) that participates in glucose-stimulated insulin secretion and is not produced by alternate splicing of the iPLA2 beta transcript.

25. Cytokines and nitric oxide inhibit the enzyme activity of catalase but not its protein or mRNA expression in insulin-producing cells.

26. Biosynthesis of hepoxilins: evidence for the presence of a hepoxilin synthase activity in rat insulinoma cells.

27. Reduction of macrophage activation after antioxidant enzymes gene transfer to rat insulinoma INS-1 cells.

28. Stimulation of insulin secretion and associated nuclear accumulation of iPLA(2)beta in INS-1 insulinoma cells.

29. Immunocytochemical localization of prohormone convertase 1/3 and 2 in pancreatic islet cells and islet cell tumors.

30. Studies of phospholipid metabolism, proliferation, and secretion of stably transfected insulinoma cells that overexpress group VIA phospholipase A2.

31. Effects of second messengers on serine/threonine protein phosphatases in insulin-secreting cells.

32. Poly(ADP-ribose) polymerase facilitates the repair of N-methylpurines in mitochondrial DNA.

33. Glucose-6-phosphatase in the insulin secreting cell line INS-1.

34. Malignant insulinoma which expressed a unique creatine kinase isoenzyme: clinical value of arterial embolization as a palliative therapy.

35. Telomerase activity in pancreatic endocrine tumours: a potential marker for malignancy.

36. Interleukin-1beta induces ornithine decarboxylase activity in insulin-producing cells.

37. Elongation of (CTG)n repeats in myotonic dystrophy protein kinase gene in tumors associated with myotonic dystrophy patients.

38. The Gly972-->Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cells.

39. Beta-cell gene expression and functional characterisation of the human insulinoma cell line CM.

40. Insulinoma with hyperproinsulinemia during hypoglycemia and loss of expression of vacuolar-type H(+)-ATPase (V-ATPase) in the tumor tissue.

41. Cloning from insulinoma cells of synapsin I associated with insulin secretory granules.

42. Glucose- and phorbol ester-induced insulin secretion in human insulinoma cells--association with protein kinase C activation.

43. Profile and differential expression of protein tyrosine phosphatases in mouse pancreatic islet tumor cell lines.

44. Insulinoma cells contain an isoform of Ca2+/calmodulin-dependent protein kinase II delta associated with insulin secretion vesicles.

45. Regulation of glycosylphosphatidylinositol-specific phospholipase D secretion from beta TC3 cells.

46. Glucose-responsitivity and expression of an ATP-stimulatable, Ca(2+)-independent phospholipase A2 enzyme in clonal insulinoma cell lines.

47. Ebselen and cytokine-induced nitric oxide synthase expression in insulin-producing cells.

48. Prohormone convertases (PC1/3 and PC2) in rat and human pancreas and islet cell tumors: subcellular immunohistochemical analysis.

49. Effects of sodium butyrate on glucose transporter and glucose-phosphorylating enzyme gene expression in RINm5F insulinoma cells.

50. Evidence for association of an ATP-stimulatable Ca(2+)-independent phospholipase A2 from pancreatic islets and HIT insulinoma cells with a phosphofructokinase-like protein.