1. Intrauterine Transmission of SARS-CoV-2
- Author
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Jullie Anne Chiste, Laura de Almeida Lanzoni, André Luiz Permegiani de Oliveira, Cyllian Arias Fugaça, Ana Paula Percicote, Lucia de Noronha, Andrea Maciel de Oliveira Rossoni, Patricia Zadorosnei Rebutini, Daniele Margarita Marani Prá, Meri Bordignon Nogueira, Emanuele Therezinha Schueda Stonoga, and Sonia Mara Raboni
- Subjects
Pathology ,diagnosis ,Epidemiology ,Expedited ,coronavirus ,lcsh:Medicine ,medicine.disease_cause ,Umbilical cord ,Lymphocytic Infiltrate ,upper respiratory swab samples ,0302 clinical medicine ,Pregnancy ,030212 general & internal medicine ,Pregnancy Complications, Infectious ,Intrauterine Transmission of SARS-CoV-2 ,swabs ,Coronavirus ,testing ,Infectious Diseases ,medicine.anatomical_structure ,coronavirus disease ,embryonic structures ,Female ,stillbirth ,Brazil ,severe acute respiratory syndrome coronavirus 2 ,Adult ,Microbiology (medical) ,medicine.medical_specialty ,placenta ,Transplacental transmission ,030231 tropical medicine ,RT-PCR ,2019 novel coronavirus disease ,lcsh:Infectious and parasitic diseases ,respiratory infections ,03 medical and health sciences ,Fetus ,autopsy ,Placenta ,Research Letter ,medicine ,Humans ,viruses ,lcsh:RC109-216 ,Fetal Death ,saliva ,SARS-CoV-2 ,business.industry ,lcsh:R ,COVID-19 ,congenital transmission ,medicine.disease ,intrauterine transmission ,Infectious Disease Transmission, Vertical ,zoonoses ,Chronic histiocytic intervillositis ,business - Abstract
We documented fetal death associated with intrauterine transmission of severe acute respiratory syndrome coronavirus 2. We found chronic histiocytic intervillositis, maternal and fetal vascular malperfusion, microglial hyperplasia, and lymphocytic infiltrate in muscle in the placenta and fetal tissue. Placenta and umbilical cord blood tested positive for the virus by PCR, confirming transplacental transmission.
- Published
- 2021