Search

Your search keyword '"Ionescu, Marius-Anton"' showing total 29 results
Start Over Author "Ionescu, Marius-Anton"
29 results on '"Ionescu, Marius-Anton"'

1. Microbiome Modulation in Acne Patients and Clinical Correlations

Author

Ionescu, Marius-Anton, primary, Tatu, Alin Laurentiu, additional, Busila, Camelia, additional, Axente, Elena Roxana, additional, Badalato, Nelly, additional, Feuilloley, Marc G. J., additional, Asquier, Estelle, additional, Martínez, José Dario, additional, and Lefeuvre, Luc, additional

Published
2024
Full Text
View/download PDF

3. DRESS and Stevens–Johnson Syndrome Overlap Secondary to Allopurinol in a 50-Year-Old Man—A Diagnostic and Treatment Challenge: Case Report

Author

Martínez, José Dario, primary, Franco, Rodolfo, additional, Sáenz, Luis Manuel, additional, Alvarado, Americo Guadalupe, additional, García, José Antonio, additional, Delgado, Sergio Máximo, additional, Ionescu, Marius-Anton, additional, Busilă, Camelia, additional, and Tatu, Alin Laurentiu, additional

Published
2023
Full Text
View/download PDF

6. University Hospital 'Saint Louis,' Paris

Author

Bagot, Martine and Ionescu, Marius-anton

Subjects
Hospitals -- France, Historic sites, Company business management, Health, Health care industry
Abstract

The Hospital 'Saint Louis' was founded in 1607 by King Henry IV of France to relieve overcrowding of Parisian hospitals during the plague epidemic of 1605-1606. He named it Saint-Louis [...]

Published
2021

13. Chilblains is a common cutaneous finding during the COVID-19 pandemic: A retrospective nationwide study from France

Author

de Masson, Adèle, primary, Bouaziz, Jean-David, additional, Sulimovic, Luc, additional, Cassius, Charles, additional, Jachiet, Marie, additional, Ionescu, Marius-Anton, additional, Rybojad, Michel, additional, Bagot, Martine, additional, Duong, Tu-Anh, additional, Denjean, Dominique, additional, Labarthe, Marie-Pierre, additional, Bézier, Maud, additional, Risbourg, Marie, additional, Payan, Geneviève, additional, Alain, Sabrina, additional, Mathivon, Frédéric, additional, Cohen-Letessier, Anny, additional, Kerob, Delphine, additional, Hellier, Jean-Philippe, additional, Comte, Christelle, additional, Keller, Fabielle, additional, Brue, Caroline, additional, Lestang, Paul, additional, Allanore, Laurence, additional, Pierkarski-Carp, Eliane, additional, Amoric, Anne, additional, Serpier, Hervé, additional, Pruvost, Philippe, additional, Guibal, Fabien, additional, Giacchero, Damien, additional, Funck-Brentano, Elisa, additional, Fortuny, Sandrine Sierra, additional, Gallay, Isabelle, additional, Zavarro, Agnès, additional, Bider-Valle, Caroline, additional, Lagrange, Sylvie, additional, Grynberg, Etty, additional, Weill, Florence, additional, Penso, Dominique, additional, Gomel, Marie, additional, Schneider, Jean, additional, Larabelle, Anne, additional, Bonhomme, Philippe, additional, Gautier, Marie-Sophie, additional, Hatchuel, Jean, additional, Mourtada, Imane, additional, Fite, Charlotte, additional, Oliveres-Ghouti, Catherine, additional, Domergue, Elisabeth, additional, Fourcade-Roch, Sabrina, additional, Lecanu, Sylvie, additional, Sebban, Nathalie, additional, Halioua, Bruno, additional, Bellut, Anne, additional, Keller, Fabienne, additional, Baratte, Isabelle, additional, Lejoyeux, Françoise, additional, Ollivaud, Laurence, additional, Abirached, Georges, additional, Burnouf, Marielle, additional, Reynayd-Mendel, Beatrix, additional, Dauendorffer, Jean-Noël, additional, Sebaoun, Joëlle, additional, Garrat, Hervé, additional, Pomper, Marie-Martine, additional, Heudes, Anne-Marie, additional, Beaulieu, Isabelle, additional, Cartier, Hugues, additional, Arsouze, Amélie, additional, Lons-Danic, Dominique, additional, Pelletier, Michèle, additional, Gallais, Valérie, additional, Piantade, Valérie, additional, Risbourg, Marlène, additional, Reuter, Georges, additional, Dahan, Serge, additional, Creusot, Murielle, additional, Kolli, Abdallah, additional, Egasse-Broca, Isabelle, additional, Rigon, Jean-Luc, additional, Sabban, Pascale, additional, Flacher, Hélène, additional, Jaillard, Benoît, additional, André, Pierre, additional, Debjoux, Dominique, additional, Poirier, Elodie, additional, Solyga, Bénédicte, additional, Perrussel, Marc, additional, Makhloufi, Sabrina, additional, Margnier, Bertrand, additional, Huzar, Clotilde, additional, Vandame, Laetitia, additional, Thelu, Hortense, additional, Chollet, Anne-Claire, additional, Marchal, Frédérique, additional, Naouri, Michael, additional, Nadaud, Marion, additional, Boissy, Elodie, additional, Lameche, Abdelhamid, additional, Berdougo, Charles, additional, Rolland, Audrey, additional, Fléchet, Marie-Laure, additional, Colonna, Gabriel, additional, Jouannet, Delphine, additional, Berdah, Isabelle, additional, Truchot, Françoise, additional, and Lavallée, Isabelle, additional

Published
2020
Full Text
View/download PDF

20. Bacillus cereus strain isolated from Demodex folliculorum in patients with topical steroid-induced rosaceiform facial dermatitis

Author

Tatu,Alin Laurentiu, Ionescu,Marius Anton, Clatici,Victor Gabriel, and Cristea,Violeta Corina

Subjects
Mass spectrometry, parasitic diseases, Rosacea, Dermoscopy, Receptors, steroid, Facial dermatoses, Mite infestations
Abstract

The aim of the study was to identify Bacillus species from the Demodex folliculorum of patients with topical steroidinduced facial rosaceiform dermatitis. Of the 75 patients examined, 20% had clinical spinulosis, while 18.66% had dermoscopic features of Demodex: follicular plugs and tails. Of the 17.33% positive patients identified upon microscopy for Demodex, samples for bacterial culture were plated on trypticase soy Colombia agar. Identification was performed by microorganisms grown method mass spectrometry. We identified a strain of Bacillus cereus.

Published
2016

25. associated in lesional areas in rosacea.

Author

Tatu, Alin Laurentiu, Ionescu, Marius Anton, and Cristea, Violeta Corina

Subjects
*ROSACEA, *DEMODEX, *BACILLUS pumilus, *SKIN, *ERYTHEMA
Abstract

The article presents a case study of a patient with erythematotelangiectatic rosacea. The patient's clinical features included red, symmetrical areas on the face accompanied by slight pruritus and burning. In this patient with rosacea linked to Demodex folliculorum, laser desorption/ionization positivity was seen for Bacillus pumilus from lesional skin scrapings.

Published
2017
Full Text
View/download PDF

26. Topical non-occlusive polymers in hand-foot syndrome

Author

Fabio Ayala, Marcello Pellicano, Gabriella Fabbrocini, Luigia Panariello, Antonio Cristaudo, Geraldine Robert, Marius-Anton Ionescu, Fabbrocini, Gabriella, Cristaudo, Antonio, Ionescu, Marius-Anton, Panariello, Luigia, Robert, Geraldine, Pellicano, Marcello, and Ayala, Fabio

Subjects
Ointment, Adult, Male, medicine.medical_specialty, Activities of daily living, Polymers, Antineoplastic Agents, Dermatology, Docetaxel, Administration, Cutaneous, Drag therapy, Severity of Illness Index, Capecitabine, Ointments, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, Quality of life, Internal medicine, Severity of illness, Medicine, Humans, Prospective Studies, Prospective cohort study, Aged, business.industry, Middle Aged, Hand-Foot Syndrome, Infectious Diseases, Treatment Outcome, Tolerability, Topical, Italy, 030220 oncology & carcinogenesis, Administration, Quality of Life, Female, Taxoids, business, medicine.drug
Abstract

Background Many cytotoxic and biological drugs are cause of severe dermatological side effects, such as hand-foot syndrome (HFS) and hand-foot skin reaction (HFSR). Oncologic patients with HFS or HFSR presents relevant symptoms that interferes with daily activities and with adherence to anticancer treatment. The HFRS control and treatment are important goals to enhance the quality of life of oncologic patients. The aim of this study was to assess the efficacy and tolerability of a b.i.d. (bis in die) topical administration of an anhydric ointment based on topical non-occlusive polymers (TNOP) in patients with HFS on current anticancer drug regiments. Methods A prospective, open, multicenter clinical study was conducted in oncologic patients with HFS attended two hospital-based Italian dermatological unit. A global-non-instrumental evaluation, based on different standardized tools (i.e., Sum Score System Index [SRRC] Score, Dermatology Life Qualiy Index [DLQI] and global efficacy) was conducted using measurements at baseline, at 4 and 8 weeks. Non-parametric test for two correlate samples, was used to assess changes in means of the different scores. The protocol was approved by ethical committee of both dermatology service pariticipating to the study. Results Twenty-one oncologic patients were enrolled. Thirteen (61.9%) of participants were female. The median age was 63 years (range: 37-73). Seventeen (80.9%) patients presenting a HFS associated to capecitabine, and four patients (19.1%) associated to docetaxel. At the enrollment, 33.3% (7/21) of patients showed at level of the hands a HFS of grade 2 and 9.5% (2/21) of grade 3. At level of the feet, 28.6% (6/21) showed a HFS of grade 2, and 17.4% (4/21) of grade 3. The SRRC scores were significantly decreased after 8 weeks of treatment compared to baseline, for both sites. In particular, SRRC score decreased from 4.38 to 1.67 (Z=-3.60, P=0.00) and from 4.48 to 1.43 (Z=-3.87, P=0.00) for hands and feet, respectively. A consistent significant improvement in the perceived QoL of patients was also observed. From baseline to visit 3, the total mean score of DLQI decreased from 10.62 to 4.57 (Δ=-57%, Z=-4.020, P=0.000). Conclusions In a sample of oncologic patients with HFS, the b.i.d. administration of TNOP for eight weeks, induced a progressive and significant decrease of the SRRC Score and a relevant improvement in the perceived quality of life.

Published
2018

27. COVID-19 skin lesions are rarely positive at RT-PCR test: the macrophage activation with vascular impact and SARS-CoV-2-induced cytokine storm.

Author

Ionescu MA

Subjects
Cytokine Release Syndrome, Humans, Macrophage Activation, Pandemics, Reverse Transcriptase Polymerase Chain Reaction, COVID-19, SARS-CoV-2
Abstract

Background: Several skin manifestations have been reported since the start of the COVID-19 pandemic: chilblains-like, livedoid lesions, urticaria-like, pseudo-Kawasaki disease, and others. Histopathologic images of these lesions most often show aspects of endothelitis, images similar to autoimmune vasculitis. Cutaneous lesions are often negative at RT-PCR for SARS-CoV-2 virus., Method and Results: We reviewed recent articles on the mechanisms of COVID-19 and we synthesized main pathways of inflammatory cascade. After the penetration into the cells of the respiratory epithelium, SARS-CoV-2 virus initiates a "cytokine storm" well described in previous publications: the expression of interferon type I (IFN-I) is one of the key elements of the antiviral response in COVID-19 patients, IFN-I expression seems to play an important role in the induction of interleukin 6 (IL-6), chemotactic factors such as Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) and the consequent activation of monocyte-macrophage system followed by the expression of TNF-alpha, and finally by the induction of coagulation factors by both extrinsic and intrinsic pathways., Conclusions: The simplified synthesis of the main pathophysiological mechanisms of COVID-19 could help us to understand at least partially the importance of macrophage activation and its vascular involvement in many skin lesions that remain often negative at in situ tests for SARS-CoV-2., (© 2021 the International Society of Dermatology.)

Published
2022
Full Text
View/download PDF

28. Topical non-occlusive polymers in hand-foot syndrome.

Author

Fabbrocini G, Cristaudo A, Ionescu MA, Panariello L, Robert G, Pellicano M, and Ayala F

Subjects
Administration, Cutaneous, Adult, Aged, Antineoplastic Agents administration & dosage, Capecitabine administration & dosage, Capecitabine adverse effects, Docetaxel, Female, Hand-Foot Syndrome etiology, Hand-Foot Syndrome pathology, Humans, Italy, Male, Middle Aged, Ointments, Prospective Studies, Severity of Illness Index, Taxoids administration & dosage, Taxoids adverse effects, Treatment Outcome, Antineoplastic Agents adverse effects, Hand-Foot Syndrome drug therapy, Polymers administration & dosage, Quality of Life
Abstract

Background: Many cytotoxic and biological drugs are cause of severe dermatological side effects, such as hand-foot syndrome (HFS) and hand-foot skin reaction (HFSR). Oncologic patients with HFS or HFSR presents relevant symptoms that interferes with daily activities and with adherence to anticancer treatment. The HFRS control and treatment are important goals to enhance the quality of life of oncologic patients. The aim of this study was to assess the efficacy and tolerability of a b.i.d. (bis in die) topical administration of an anhydric ointment based on topical non-occlusive polymers (TNOP) in patients with HFS on current anticancer drug regiments., Methods: A prospective, open, multicenter clinical study was conducted in oncologic patients with HFS attended two hospital-based Italian dermatological unit. A global-non-instrumental evaluation, based on different standardized tools (i.e., Sum Score System Index [SRRC] Score, Dermatology Life Qualiy Index [DLQI] and global efficacy) was conducted using measurements at baseline, at 4 and 8 weeks. Non-parametric test for two correlate samples, was used to assess changes in means of the different scores. The protocol was approved by ethical committee of both dermatology service pariticipating to the study., Results: Twenty-one oncologic patients were enrolled. Thirteen (61.9%) of participants were female. The median age was 63 years (range: 37-73). Seventeen (80.9%) patients presenting a HFS associated to capecitabine, and four patients (19.1%) associated to docetaxel. At the enrollment, 33.3% (7/21) of patients showed at level of the hands a HFS of grade 2 and 9.5% (2/21) of grade 3. At level of the feet, 28.6% (6/21) showed a HFS of grade 2, and 17.4% (4/21) of grade 3. The SRRC scores were significantly decreased after 8 weeks of treatment compared to baseline, for both sites. In particular, SRRC score decreased from 4.38 to 1.67 (Z=-3.60, P=0.00) and from 4.48 to 1.43 (Z=-3.87, P=0.00) for hands and feet, respectively. A consistent significant improvement in the perceived QoL of patients was also observed. From baseline to visit 3, the total mean score of DLQI decreased from 10.62 to 4.57 (Δ=-57%, Z=-4.020, P=0.000)., Conclusions: In a sample of oncologic patients with HFS, the b.i.d. administration of TNOP for eight weeks, induced a progressive and significant decrease of the SRRC Score and a relevant improvement in the perceived quality of life.

Published
2018
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results