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144 results on '"Islam, Rabia"'

1. Abstract 4146163: Statewide Burden of Ischemic Heart Disease Attributable to High Temperature in India and its Burden from 1990-2021: A Benchmarking Systematic Analysis for the Global Burden of Disease Study 2021

Author

Giri, Tapan, gopi, Anaswara, Surana, Deval, Ahmed, Danish, Shandilya, Ashwinikumar, Lakkimsetti, Mohit, Syed, Saif, AMIN, VISHRANT, Islam, Rabia, Bhalodia, Paritaben, PATEL, JUHI, DESAI, HARDIK, sharma, kamal, and Thakkar, Kshitija Manishbhai

Published
2024
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8. Efficacy of Metformin-Cabergoline Compared to Metformin Monotherapy for Management of PCOS With Hyperprolactinemia: A Systematic Review and Meta-analysis.

Author

Kumar, Aakash, Nazim, Ahsan, Maheshwari, Mahveer, Kumari, Nisha, Kumar, Purneet, Lohana, Chandar Kanta, Kala, Deep, Ali, Khansa, Raj, Hem, Islam, Hamza, Islam, Rabia, and Riaz, Monazza

Abstract

Background: Metformin plays a major part in the treatment of polycystic ovarian syndrome.Trials are being conducted to compare the effectiveness of combination of metformin with cabergoline in the treatment of hyperprolactinemia and polycystic ovarian syndrome. Objectives: The purpose of this study is to compare the effectiveness of metformin monotherapy and combination therapy with cabergoline versus metformin for the management of polycystic ovarian syndrome with hyperprolactinemia. Methodology: An extensive search up until 31 May 2024 of electronic databases (PubMed, Registry of Controlled Clinical Trials, Web of Sciences, SCOPUS) to find pertinent studies. An analysis was conducted with both observational data and randomized clinical trials. To compute the standard mean difference, weighted mean difference, odds ratio, and 95% confidence interval, RevMan (v5.3) was utilized. Primary outcomes that were assessed included body-mass index, regular menstruation, weight change, prolactin, testosterone, and dehydroepiandrosterone-sulfate levels. Results: Three randomized controlled trials and 1 observational study, taking a total patient population of n = 535, were part of our final analysis. Prolactin (SMD = −3.23 95% CI: (−4.90, −1.55)) and dehydroepiandrosterone-sulfate levels (SMD = −0.27 95% CI: (−0.52, −0.01)) were significantly lower in the metformin and cabergoline combination therapy group; monthly regularity was also significantly higher (OR = 3.07 95% CI: (2.09, 4.51)). Statistically, there was no significant difference in weight, body-mass index, or testosterone levels. Conclusions: In the treatment of polycystic ovarian syndrome, the combination of metformin and cabergoline significantly lowers prolactin levels and encourages regular menstrual cycles. Although metformin has the potential to suppress testosterone levels, more investigation is required to determine how combination therapy affect dehydroepiandrosterone-sulfate and testosterone levels. It's interesting to note that while neither intervention had a substantial impact on weight or body-mass index, metformin and cabergoline combination therapy outperformed metformin monotherapy in terms of supporting regular menstrual cycles. Customized therapy approaches are essential, and large-scale trials involving a variety of groups are required to comprehend the safety and effectiveness of treatments. Plain language summary: Efficacy of metformin compared to metformin and cabergoline combination In this study, 2 therapies for women with high prolactin levels—a hormone associated with PCOS—were examined. Their goal was to determine which combination of metformin and cabergoline produced the best results.Observational data and randomized clinical trials were included while searching through several databases for pertinent studies. Researchers discovered that the combination of metformin and cabergoline was superior to using metformin alone in reducing prolactin and another hormone called DHEAS. The menstrual periods of women receiving the combined therapy were also more regular. However, there wasn't much difference in weight, body mass index (BMI), or testosterone levels between the 2 groups. In summary, it appears that the combination of cabergoline and metformin is a more effective way to treat the symptoms of PCOS, which include irregular periods and elevated prolactin levels. To find out how it impacts other hormones and whether it's long-term safe and effective, further research is still required. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Efficacy and Safety of Intravenous Diltiazem Versus Metoprolol in the Management of Atrial Fibrillation with Rapid Ventricular Response in the Emergency Department: A Comprehensive Umbrella Review of Systematic Reviews and Meta-analyses.

Author

JAYA, FNU, AFZAL, MARIA, ANUSHA, FNU, KUMARI, MUSKAN, KUMAR, AJAY, SALEEM, SAQIB, KUMAR, AMAN, BHATIA, VISHAL, ISLAM, RABIA, KUMAR, MANOJ, KUMAR, RAMEET, ISLAM, HAMZA, MUZAMMIL, MUHAMMAD ALI, KUMAR, SATESH, and KHATRI, MAHIMA

Published
2024
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12. Evaluating the Efficacy of Antioxidant Therapy in Enhancing the Quality of Life of Chronic Pancreatitis Patients: A Systematic Review

Author

Al Balushi, Hamza, primary, Ahmed, Junaid, additional, Ahuja, Laksh Kumar, additional, Barkha, FNU, additional, Shafeeq, Mohamed Ishraq, additional, Baluch, Amna B, additional, Altinkaynak, Yahya, additional, Abdallah, Shenouda, additional, Islam, Hamza, additional, Islam, Rabia, additional, Rehman, Abdur, additional, Shehryar, Abdullah, additional, and Raza, Ali, additional

Published
2024
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13. From Sugar Spikes to Pressure Peaks: Navigating the World of Diabetes, Hypertension, Obesity, and Kidney Health

Author

Hlyan, Nay Phone, primary, Arif, Talha, additional, Jaufar, Saina S, additional, Rehman, Abdur, additional, Ayalew, Biruk D, additional, Batu, Biniyam J, additional, Hundesa, Muhidin I, additional, Hlaing, May Su, additional, Islam, Hamza, additional, Islam, Rabia, additional, Shehryar, Abdullah, additional, and Quinn, Maria, additional

Published
2024
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15. SPAK inhibitor ZT‐1a attenuates reactive astrogliosis and oligodendrocyte degeneration in a mouse model of vascular dementia

Author

Bhuiyan, Mohammad Iqbal H., primary, Habib, Khadija, additional, Sultan, Md Tipu, additional, Chen, Fenghua, additional, Jahan, Israt, additional, Weng, Zhongfang, additional, Rahman, Md Shamim, additional, Islam, Rabia, additional, Foley, Lesley M., additional, Hitchens, T. Kevin, additional, Deng, Xianming, additional, Canna, Scott W., additional, Sun, Dandan, additional, and Cao, Guodong, additional

Published
2024
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17. Sertraline versus escitalopram in South Asians with moderate to severe major depressive disorder: (SOUTH-DEP) a double-blind, parallel, randomized controlled trial

Author

Raza, Sidra, primary, Ahmed, Saddique, additional, Islam, Rabia, additional, Ahmed, Muhammad, additional, Ashraf, Sandal, additional, Islam, Hamza, additional, Kiyani, Hifza, additional, Saqib, Muhammad, additional, Shah, Syed Abdul Rehman, additional, and Mumtaz, Hassan, additional

Published
2023
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20. Comparative Efficacy and Safety Profiles of High-power, Short-duration and Low-power, Long-duration Radiofrequency Ablation in Atrial Fibrillation: A Systematic Review and Meta-analysis

Author

KUMAR, SATESH, primary, KHATRI, MAHIMA, additional, KUMAR, SUMEET, additional, PARTAB, F.N.U., additional, KUMAR, F.N.U., additional, NEHA, F.N.U., additional, SUMAN, F.N.U., additional, RAI, LAJPAT, additional, SANGAM, F.N.U., additional, KUMARI, SIMRAN, additional, ISLAM, HAMZA, additional, ISLAM, RABIA, additional, and PATEL, TIRATH, additional

Published
2023
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24. The Effect of Non-Renewable and Renewable Energy Consumption on CO2 Emissions: Evidence from Pakistan

Author

Islam, Rabia, Bhatti, Muhammad Kamran, Sundas, Hassan, Ali, Shaukat, Sidra, Islam, Rabia, Bhatti, Muhammad Kamran, Sundas, Hassan, Ali, and Shaukat, Sidra

Abstract

Concerns over the harmful consequences of climate change and global warming have grown since the 1990s. The primary subjects of discussion when it comes to climate change are energy production and consumption, as burning fossil fuels is the primary purpose of greenhouse gas emissions. Furthermore, using fossil fuels to produce commodities endangers human health and contributes to environmental damage. Clean, sustainable energy sources that are abundant in the natural world and do not pollute the air are becoming more and more important to modern cultures. This study looks at the long-run relationship between CO2 (carbon emissions) in Asian countries between 1990 and 2021 and the utilization of non-renewable and renewable energy sources. The significance of renewable energy sources and their impact on CO2 emissions are the main points of emphasis. According to the data, using nonrenewable energy sources causes CO2 emissions to increase, while using renewable energy sources causes them to decrease. CO2 (carbon emissions) and economic growth are positively correlated; as growth picks up speed, so do emissions. Furthermore, the square of economic expansion produces the opposite effect, lowering emissions of carbon dioxide. This observation lends credence to the Kuznets theory. Moreover, even though foreign direct investment has the opposite effect, the rate of urbanization is one of the reasons of the rise in CO2 (carbon emissions).

Published
2023

25. Clinical Outcomes of Polymer-Free Versus Polymer-Coated Drug-Eluting Stents in Patients With Coronary Artery Disease: A Systematic Review and Meta-Analysis

Author

Khatri, Mahima, primary, Kumar, Satesh, additional, Mahfooz, Kamran, additional, Sugandh, FNU, additional, Dembra, Deepak, additional, Mehak, FNU, additional, Rachna Panjwani, Gianeshwaree Alias, additional, Islam, Hamza, additional, Islam, Rabia, additional, Ibn e Ali Jaffari, Syed Muhammad, additional, Patel, Tirath, additional, Kumar, Ajay, additional, Kumar, Nomesh, additional, and Varrassi, Giustino, additional

Published
2023
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31. Comparative efficacy and safety profile of high-power short duration with low power long duration radiofrequency ablation in atrial fibrillation: An updated systematic review and meta-analysis

Author

Kumar, Satesh, primary, Khatri, Mahima, additional, kumar, Sumeet, additional, FNU, Partab, additional, FNU, Manoj Kumar, additional, FNU, Neha, additional, FNU, Suman, additional, Rai, Lajpat, additional, FNU, Sangam, additional, Kumari, Simran, additional, Islam, Hamza, additional, and Islam, Rabia, additional

Published
2023
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44. Additional file 2: of MicroRNA suppression of stress-responsive NDRG2 during dexamethasone treatment in skeletal muscle cells

Author

Mir, Bilal, Islam, Rabia, Kalanon, Ming, Russell, Aaron, and Foletta, Victoria

Subjects
animal structures, genetic structures, viruses, fungi, embryonic structures
Abstract

Figure S2. MiRNA expression following combined miRNA mix transfection. MiRNA levels of (A) miR-23a (dark grey bars), (B) miR-23b, (light grey bars), and (C) miR-28 (white bars) following transfection of miRNA mix or negative control (NC) miRNA (black bars) at 48 h post transfection. Data are representative of two independent experiments with n = 4 per sample group. ***p

Published
2019
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45. Additional file 1: of MicroRNA suppression of stress-responsive NDRG2 during dexamethasone treatment in skeletal muscle cells

Author

Mir, Bilal, Islam, Rabia, Kalanon, Ming, Russell, Aaron, and Foletta, Victoria

Subjects
genetic structures
Abstract

Figure S1. miR-23a, -23b and -28 expression levels following miRNA transfection in C2C12 myotubes. Time-course in hours (h) of miR-23a, -23b and -28 expression levels following transfection of (A) miR-23a (dark grey bars), (B) miR-23b (light grey bars), and (C) miR-28 (white bars) compared to negative control (NC) miRNA (black bars) at 12, 24 or 48 h post transfection. Data are representative of two independent experiments with n = 4 per sample group. **p

Published
2019
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47. MicroRNA suppression of stress-responsive NDRG2 during dexamethasone treatment in skeletal muscle cells

Author

Mir, Bilal Ahmad, Islam, Rabia, Kalanon, Ming, Russell, Aaron, Foletta, Victoria, Mir, Bilal Ahmad, Islam, Rabia, Kalanon, Ming, Russell, Aaron, and Foletta, Victoria

Abstract

BACKGROUND: MicroRNAs (miRNAs) are increasingly being identified as modulatory molecules for physiological and pathological processes in muscle. Here, we investigated whether miRNAs influenced the expression of the stress-responsive gene N-myc downstream-regulated gene 2 (Ndrg2) in skeletal muscle cells through the targeted degradation or translation inhibition of NDRG2 mRNA transcripts during basal or catabolic stress conditions. RESULTS: Three miRNAs, mmu-miR-23a-3p (miR-23a), mmu-miR-23b-3p (miR-23b) and mmu-miR-28-5p (miR-28), were identified using an in silico approach and confirmed to target the 3' untranslated region of the mouse Ndrg2 gene through luciferase reporter assays. However, miR-23a, -23b or -28 overexpression had no influence on NDRG2 mRNA or protein levels up to 48 h post treatment in mouse C2C12 myotubes under basal conditions. Interestingly, a compensatory decrease in the endogenous levels of the miRNAs in response to each other's overexpression was measured. Furthermore, dexamethasone, a catabolic stress agent that induces NDRG2 expression, decreased miR-23a and miR-23b endogenous levels at 24 h post treatment suggesting an interplay between these miRNAs and NDRG2 regulation under similar stress conditions. Accordingly, when overexpressed simultaneously, miR-23a, -23b and -28 attenuated the dexamethasone-induced increase of NDRG2 protein translation but did not affect Ndrg2 gene expression. CONCLUSION: These findings highlight modulatory and co-regulatory roles for miR-23a, -23b and -28 and their novel regulation of NDRG2 during stress conditions in muscle.

Published
2019

49. Peptidyl-prolyl cis–trans isomerase NIMA interacting 1 regulates skeletal muscle fusion through structural modification of Smad3 in the linker region

Author

Islam, Rabia, Yoon, Heein, Shin, Hye‐Rim, Bae, Han‐Sol, Kim, Bong‐Soo, Yoon, Won‐Joon, Woo, Kyung‐Mi, Baek, Jeong‐Hwa, Lee, Yun‐Sil, Ryoo, Hyun‐Mo, Islam, Rabia, Yoon, Heein, Shin, Hye‐Rim, Bae, Han‐Sol, Kim, Bong‐Soo, Yoon, Won‐Joon, Woo, Kyung‐Mi, Baek, Jeong‐Hwa, Lee, Yun‐Sil, and Ryoo, Hyun‐Mo

Published
2018

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