1. Retrospective screening of solid organ donors in Italy, 2009, reveals unpredicted circulation of West Nile virus
- Author
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Capobianchi, Mr, Sambri, V, Castilletti, C, Pierro, Am, Rossini, G, Gaibani, P, Cavrini, F, Selleri, M, Meschi, S, Lapa, D, Di Caro, A, Grossi, P, De Cillia, C, Venettoni, S, Landini, Mp, Ippolito, G, Nanni Costa, A, Italian Transplant Network Collaborators: Scalamogna, M, Famulari, A, Saracino, A, Giacon, B, Mancini, P, Di Florio, E, Ridolfi, L, Peressutti, R, Adorno, D, Castiglione, Ag, Vesconi, S, Testasecca, D, Amoroso, Antonio, Schena, Fp, Carcassi, C, Sparacino, V, Lippi, R, Gabardi, E, Gambelunghe, C, Calabrò, F., Capobianchi M.R., Sambri V., Castilletti C., Pierro A.M., Rossini G., Gaibani P., Cavrini F., Selleri M., Meschi S., Lapa D., Di Caro A., Grossi P., De Cillia C., Venettoni S., Landini M., Ippolito G., and Nanni Costa A.
- Subjects
SOLID ORGAN TRANSPLANT ,Adult ,organ donor ,Epidemiology ,West Nile virus ,animal diseases ,viruses ,medicine.disease_cause ,Virus ,Flaviviridae ,West nile virus ,screening ,transplantation ,Predictive Value of Tests ,Virology ,medicine ,Humans ,Aged ,Retrospective Studies ,Aged, 80 and over ,biology ,business.industry ,Transmission (medicine) ,SEROPREVALENCE ,Public Health, Environmental and Occupational Health ,virus diseases ,Retrospective cohort study ,Middle Aged ,biology.organism_classification ,Health Surveys ,Tissue Donors ,nervous system diseases ,Transplantation ,Flavivirus ,Italy ,Immunology ,Risk assessment ,business ,West Nile Fever - Abstract
Since the occurrence of West Nile virus (WNV) infection in humans in 2008 in Italy, concerns have been raised about the potential risks associated with solid organ transplantation (SOT). A nationwide retrospective survey showed that 1.2% of SOT donors in 2009 were WNV-seropositive and demonstrated that human WNV infection is distributed throughout several Italian regions. Transmission of WNV or other arboviruses through SOT is a possibility and risk assessment should be carried out before SOT to avoid infection through transplantation.