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265 results on '"Italiano, Domenico"'

2. Mood Stabilizers

Author

Spina, Edoardo, Italiano, Domenico, Jann, Michael W., editor, Penzak, Scott R., editor, and Cohen, Lawrence J., editor

Published
2016
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5. Minor and Repetitive Head Injury

Author

Buki, Andras, Kovacs, Noemi, Czeiter, Endre, Schmid, Kara, Berger, Rachel P., Kobeissy, Firas, Italiano, Domenico, Hayes, Ronald L., Tortella, Frank C., Mezosi, Emese, Schwarcz, Attila, Toth, Arnold, Nemes, Orsolya, Mondello, Stefania, Schramm, Johannes, Series editor, and Akalan, Nejat, Series editor

Published
2015
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24. Minor and Repetitive Head Injury

Author

Buki, Andras, primary, Kovacs, Noemi, additional, Czeiter, Endre, additional, Schmid, Kara, additional, Berger, Rachel P., additional, Kobeissy, Firas, additional, Italiano, Domenico, additional, Hayes, Ronald L., additional, Tortella, Frank C., additional, Mezosi, Emese, additional, Schwarcz, Attila, additional, Toth, Arnold, additional, Nemes, Orsolya, additional, and Mondello, Stefania, additional

Published
2014
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28. Additional file 1 of Artificial intelligence for reduced dose 18F-FDG PET examinations: a real-world deployment through a standardized framework and business case assessment

Author

Katsari, Katia, Penna, Daniele, Arena, Vincenzo, Polverari, Giulia, Ianniello, Annarita, Italiano, Domenico, Milani, Rolando, Roncacci, Alessandro, Illing, Rowland O., and Pelosi, Ettore

Abstract

Additional file 1: Appendix 1. Seven PET-negative patients outside the study protocol were injected with standard 18F-FDG dose and acquired at 60 minutes post-injection. A subsequent second scan of the upper abdomen was obtained, using the same elapsed time used in the study protocol. By the comparison of the liver 18F-FDG uptake in the two scans, a correction factor of 1.063 was extracted and applied when comparing SUV values in PET-processed vs. PET-native images. Results are presented in Supplemental Table 1. Supplemental Table 1. Data for SUV correction factor. Supplemental Table 2. Study population.

Published
2021
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32. Artificial Intelligence for Reduced Dose 18F-FDG PET Examinations: A Real-World Deployment Through a Standardized Framework and Business Case Assessment

Author

Penna, Daniele, primary, Katsari, Katia, additional, Arena, Vincenzo, additional, Polverari, Giulia, additional, Ianniello, Annarita, additional, Italiano, Domenico, additional, Milani, Rolando, additional, Roncacci, Alessandro, additional, Pelosi, Ettore, additional, and Illing, Rowland, additional

Published
2020
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33. Artificial intelligence for reduced dose 18F-FDG PET examinations: A real-world deployment through a standardized framework and business case assessment

Author

Katsari, Katia, primary, Penna, Daniele, additional, Arena, Vincenzo, additional, Polverari, Giulia, additional, Ianniello, Annarita, additional, Italiano, Domenico, additional, Milani, Rolando, additional, Roncacci, Alessandro, additional, Illing, Rowland, additional, and Pelosi, Ettore, additional

Published
2020
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38. Indications of newer and older anti-epileptic drug use: findings from a southern Italian general practice setting from 2005-2011

Author

Italiano, Domenico, Alibrandi, Angela, Ferrara, Rosarita, Cannata, Angelo, Trifirò, Gianluca, Sultana, Janet, Tari, Michele, Tari, Daniele Ugo, Perrotta, Margherita, Pagliaro, Claudia, Spina, Edoardo, Arcoraci, Vincenzo, CAPUANO, Annalisa, FERRAJOLO, Carmen, RAFANIELLO, Concetta, Italiano, Domenico, Capuano, Annalisa, Alibrandi, Angela, Ferrara, Rosarita, Cannata, Angelo, Trifirò, Gianluca, Sultana, Janet, Ferrajolo, Carmen, Tari, Michele, Tari, Daniele Ugo, Perrotta, Margherita, Pagliaro, Claudia, Rafaniello, Concetta, Spina, Edoardo, and Arcoraci, Vincenzo

Subjects
Male, Time Factors, Databases, Factual, General Practice, Sex Factor, General practice, antiepileptics, incidence, indications of use, prescriptions, prevalence, Drug Utilization Review, Drug Prescription, Anticonvulsant, Prevalence, Age Factor, Pharmacology (medical), Practice Patterns, Physicians', Analgesics, Drug Cost, General Practitioner, Incidence, Age Factors, Middle Aged, Italy, Insurance, Health, Reimbursement, Anticonvulsants, Female, Human, Antipsychotic Agents, Adult, Mood Disorder, Time Factor, Adolescent, Pain, anti-epileptic, Drug Prescriptions, Drug Costs, Young Adult, Sex Factors, General Practitioners, Humans, Aged, Pharmacology, prescription, Epilepsy, Mood Disorders, Pharmacoepidemiology, Antipsychotic Agent, Health Care Survey, Health Care Surveys, Analgesic
Abstract

Aims The aim of the study was to analyze the prescribing pattern of both newer and older AEDs. Methods A population of almost 150 000 individuals registered with 123 general practitioners was included in this study. Patients who received at least one AED prescription over 2005-2011 were identified. The 1 year prevalence and cumulative incidence of AED use, by drug class and individual drug, were calculated over the study period. Potential predictors of starting therapy with newer AEDs were also investigated. Results The prevalence of use per 1000 inhabitants of older AEDs increased from 10.7 (95% CI10.1, 11.2) in 2005 to 13.0 (95% CI12.4, 13.6) in 2011, while the incidence remained stable. Newer AED incidence decreased from 9.4 (95% CI 8.9, 9.9) in 2005 to 7.0 (95% CI 6.6, 7.5) in 2011, with a peak of 15.5 (95% CI 14.8, 16.1) in 2006. Phenobarbital and valproic acid were the most commonly prescribed AEDs as starting therapy for epilepsy. Gabapentin and pregabalin accounted for most new pain-related prescriptions, while valproic acid and lamotrigine were increasingly used for mood disorders. Female gender (OR 1.36, 95% CI 1.20, 1.53), age ranging between 45-54 years (OR 1.39, 95% CI 1.16, 1.66) and pain as an indication (OR 16.7, 95% CI, 13.1, 21.2) were associated with newer AEDs starting therapy. Conclusions Older AEDs were mainly used for epileptic and mood disorders, while newer drugs were preferred for neuropathic pain. Gender, age, indication of use and year of starting therapy influenced the choice of AED type. The decrease of newer AED use during 2007 is probably related to the restricted reimbursement criteria for gabapentin and pregabalin.

Published
2014

46. Protective effect of apocynin, a NADPH-oxidase inhibitor, against contrast-induced nephropathy in the diabetic rats: a comparison with n-acetylcysteine

Author

Ahmad, A, Mondello, Stefania, Di Paola, R, Mazzon, E, Esposito, Emanuela, Catania, MARIA ANTONIETTA, Italiano, Domenico, Mondello, Patrizia, Aloisi, Carmela, Cuzzocrea, Salvatore, and DI PAOLA, Rosanna

Subjects
Male, medicine.medical_specialty, Time Factors, Kidney Glomerulus, Contrast-induced nephropathy, Iomeprol, Contrast Media, Apoptosis, Acetylcysteine, NADPH-oxidase inhibitor, chemistry.chemical_compound, Cytosine, Lipocalin-2, apocynin, Internal medicine, Proto-Oncogene Proteins, nephropathy in the diabetic rats, medicine, Animals, Diabetic Nephropathies, Enzyme Inhibitors, Rats, Wistar, Glutathione Transferase, Pharmacology, NADPH oxidase, biology, Nitrotyrosine, Sodium, Acetophenones, NADPH Oxidases, medicine.disease, Streptozotocin, Lipocalins, Iopamidol, Rats, Enzyme Activation, Isoenzymes, Endocrinology, chemistry, Apocynin, biology.protein, Potassium, Tyrosine, Poly(ADP-ribose) Polymerases, Nicotinamide adenine dinucleotide phosphate, medicine.drug, Acute-Phase Proteins
Abstract

The aim of this study was to investigate the effects of apocynin, a NADPH (nicotinamide adenine dinucleotide phosphate)-oxidase inhibitor, in diabetic rats with nephropathy induced by contrast medium (CIN). Diabetes was induced in male Wistar rats by a single dose of streptozotocin (60 mg/kg i.v.). Animals were then divided into the following groups: 1) control group (diabetic rats treated i.v. with saline solution); 2) iomeprol group (iomeprol at 10 ml/kg was injected i.v. 30 min after saline administration); 3) apocynin group (identical to the iomeprol group, except for pre-treatment with apocynin 5mg/kg i.v., 30 min before iomeprol injection) and 4) N-acetylcysteine group (NAC) (same as iomeprol group, except for the treatment with NAC 20 mg/kg i.v. 30 min before iomeprol injection). CIN in animals were assessed 24h after administration of iomeprol. Apocynin significantly attenuates the impaired glomerular function, concentration of Na(+), K(+), alpha glutathione S-transferase levels in urine and neutrophil gelatinase-associated lipocalin levels in plasma caused by iomeprol. In kidney, immunohistochemical analysis of some inflammatory mediators, such as nitrotyrosine, poly-ADP-ribosyl polymerase, tumor necrosis factor-α, interleukin-1β as well as apoptosis (evaluated as terminal deoxynucleotidyltransferase-mediated UTP end labeling assay) revealed positive staining in tissue obtained from iomeprol group. These parameters were markedly reduced in animals treated with apocynin. Similarly, these parameters were also markedly modified by NAC pre-treatment. Here, we have shown that apocynin attenuates the degree of iomeprol-induced nephropathy in diabetic rats.

Published
2011

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