1. An occlusive dressing containing betamethasone valerate 0.1% for the treatment of prurigo nodularis.
- Author
-
Saraceno, Rosita, Chiricozzi, Andrea, Nisticò, Steven Paul, Tiberti, Sergio, and Chimenti, Sergio
- Subjects
- *
PRURIGO , *OCCLUSIVE surgical dressings , *OINTMENTS , *ITCHING , *NODULAR disease , *PREVENTION , *THERAPEUTICS - Abstract
Introduction: Prurigo nodularis is a distressing condition characterized by the presence of multiple nodules associated with intense pruritus. Objective: To assess the clinical efficacy and safety of betamethasone valerate 0.1% tape and a moisturizing itch-relief cream in prurigo nodularis. Methods: Twelve patients were enrolled in this pilot comparison of betamethasone valerate 0.1% tape versus a moisturizing itch-relief cream containing feverfew. The study period was 4 weeks. Clinical evaluation was performed weekly. Results: Eleven subjects completed the 4 weeks of therapy. The mean visual analogue scale (VAS) for pruritus at baseline was 8.75 for both sides of the body. The side treated with betamethasone valerate 0.1% tape showed a higher clinical response (VAS score at week 4: 3.9; p < 0.005) compared with the side treated with moisturizing itch-relief cream (VAS score at week 4: 5.6; p < 0.005). Conclusion: Both treatments were effective. However, the occlusive dressing enhanced the efficacy of the treatment, preventing scratching. [ABSTRACT FROM AUTHOR]
- Published
- 2010
- Full Text
- View/download PDF