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7. Femtosecond Laser Irradiation to Zirconia Prior to Calcium Phosphate Coating Enhances Osteointegration of Zirconia in Rabbits.

Author

Mutsuzaki, Hirotaka, Yashiro, Hidehiko, Kakehata, Masayuki, Oyane, Ayako, and Ito, Atsuo

Subjects
CALCIUM phosphate, PHOSPHATE coating, FEMTOSECOND lasers, OSSEOINTEGRATION, ZIRCONIUM oxide, PULSED laser deposition
Abstract

Calcium phosphate (CaP) coating of zirconia and zirconia-based implants is challenging, due to their chemical instability and susceptibility to thermal and mechanical impacts. A 3 mol% yttrium-stabilized tetragonal zirconia polycrystal was subjected to femtosecond laser (FsL) irradiation to form micro- and submicron surface architectures, prior to CaP coating using pulsed laser deposition (PLD) and low-temperature solution processing. Untreated zirconia, CaP-coated zirconia, and FsL-irradiated and CaP-coated zirconia were implanted in proximal tibial metaphyses of male Japanese white rabbits for four weeks. Radiographical analysis, push-out test, alizarin red staining, and histomorphometric analysis demonstrated a much improved bone-bonding ability of FsL-irradiated and CaP-coated zirconia over CaP-coated zirconia without FsL irradiation and untreated zirconia. The failure strength of the FsL-irradiated and CaP-coated zirconia in the push−out test was 6.2–13.1-times higher than that of the CaP-coated zirconia without FsL irradiation and untreated zirconia. Moreover, the adhesion strength between the bone and FsL-irradiated and CaP-coated zirconia was as high as that inducing host bone fracture in the push-out tests. The increased bone-bonding ability was attributed to the micro-/submicron surface architectures that enhanced osteoblastic differentiation and mechanical interlocking, leading to improved osteointegration. FsL irradiation followed by CaP coating could be useful for improving the osteointegration of cement-less zirconia-based joints and zirconia dental implants. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Clinical Trial for the Safety and Feasibility of Pedicle Screws Coated with a Fibroblast Growth Factor-2-Apatite Composite Layer for Posterior Cervical Fusion Surgery

Author

Nagashima, Katsuya, primary, Hara, Yuki, additional, Mutsuzaki, Hirotaka, additional, Totoki, Yasukazu, additional, Okano, Eriko, additional, Mataki, Kentaro, additional, Matsumoto, Yukei, additional, Yanagisawa, Yohei, additional, Noguchi, Hiroshi, additional, Sogo, Yu, additional, Ito, Atsuo, additional, Koda, Masao, additional, and Yamazaki, Masashi, additional

Published
2023
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25. Safety/feasibility study of pedicle screws coated with a fibroblast growth factor-2-calcium phosphate composite layer for posterior cervical fusion surgery

Author

Nagashima, Katsuya, primary, Hara, Yuki, additional, Mutsuzaki, Hirotaka, additional, Totoki, Yasukazu, additional, Okano, Eriko, additional, Mataki, Kentaro, additional, Matsumoto, Yukei, additional, Yanagisawa, Yohei, additional, Noguchi, Hiroshi, additional, Sogo, Yu, additional, Ito, Atsuo, additional, Koda, Masao, additional, and Yamazaki, Masashi, additional

Published
2022
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42. Magnetization switching experiments on sub-micron Co/Pt multilayer dot using a pulse field generator with nanoseconds duration

Author

Ito, Atsuo, Kikuchi, Nobuaki, Okamoto, Satoshi, and Kitakami, Osamu

Subjects
Capacitors -- Usage, Magnetic fields -- Models, Magnetic fields -- Analysis, Magnetization -- Analysis, Business, Electronics, Electronics and electrical industries
Abstract

A pulse generator with large amplitude of 160 V and fast rise time of less than 0.4 ns has been built using a coaxial cable as a capacitor. By combining with the anomalous Hail effect technique for a single magnetic nanodot, magnetization response of one Co/Pt nanodot of 400 nm in diameter to the pulse was examined. By applying a pulse field with the maximum amplitude of 740 Oe and the duration of 10 ns, magnetization switching of the dot by the pulse was successfully observed. The pulse amplitude dependence of switching field suggested that the pulse field and the dc bias field could be treated as a simple summation of the both fields in the time scale of 10 ns. All the results of magnetization switching by the pulse field could be explained qualitatively by classical thermal relaxation process. Index Terms--Anomalous Hall effect, Co/Pt multilayer, magnetization dynamics, magnetization reversal, single nanodot.

Published
2008

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