1. Improved midterm outcomes after endovascular repair of nontraumatic descending thoracic aortic rupture compared with open surgery
- Author
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A. Claire Watkins, Yukihisa Ogawa, Itoga K. Nathan, Hao He, Michael D. Dake, Shinichi Iwakoshi, Michael P. Fischbein, Y. Joseph Woo, Peter Chiu, Bharathi Lingala, and Jason T. Lee
- Subjects
Pulmonary and Respiratory Medicine ,Male ,medicine.medical_specialty ,medicine.medical_treatment ,Aortic Rupture ,030204 cardiovascular system & hematology ,Single Center ,Independent predictor ,03 medical and health sciences ,0302 clinical medicine ,Postoperative Complications ,medicine ,Humans ,Prolonged ventilation ,Aortic rupture ,Stroke ,Aged ,Retrospective Studies ,Aged, 80 and over ,Aortic Aneurysm, Thoracic ,business.industry ,Open surgery ,Endovascular Procedures ,Spinal cord ischemia ,Middle Aged ,Thoracic Surgical Procedures ,medicine.disease ,Surgery ,Treatment Outcome ,030228 respiratory system ,Female ,Hemodialysis ,Cardiology and Cardiovascular Medicine ,business - Abstract
Background Thoracic endovascular aortic repair (TEVAR) has become first-line treatment for descending thoracic aortic rupture (DTAR), but its midterm and long-term outcomes remain undescribed. This study evaluated whether TEVAR would improve midterm outcomes of nontraumatic DTAR relative to open surgical repair (OSR). Methods Between December 1999 and October 2018, 118 patients with DTAR were treated with either OSR (n = 39) or TEVAR (n = 79) at a single center. Primary end points were 30-day and long-term all-cause mortalities. Secondary end points included stroke, permanent spinal cord ischemia (SCI), prolonged ventilation support or tracheostomy, permanent hemodialysis, and aortic reintervention. Results Thirty-day mortality was significantly lower with TEVAR (OSR, 38.5%; TEVAR, 16.5%; P = .01). Stroke (15.6% vs 3.8%; P = .03), permanent SCI (15.6% vs 2.5%; P = .02), prolonged ventilation (30.8% vs 8.9%; P = .002), and tracheostomy (12.8% vs 2.5%; P = .04) were significantly lower after TEVAR than OSR. Need for hemodialysis trended higher after OSR (12.8% vs 5.1%; P = .2). Mean follow ups were 1048 ± 1591 days for OSR group and 828 ± 1258 days for TEVAR. All-cause mortality at last follow-up was significantly lower after TEVAR than OSR (35.4% vs 66.7%; P = .001). Aortic reintervention was required more frequently within 30 days after TEVAR (15.2% vs 2.6%; P = .06). By multivariate analysis, TAAA was an independent predictor for mortality. Conclusions TEVAR improves both early and midterm outcomes of DTAR relative to OSR. TAAA was a predictor of mortality. Endovascular approach to DTAR may provide the greatest chance at survival.
- Published
- 2019