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18 results on '"Iurilli, Valentina"'

3. AmBisome ® Formulations for Pediatrics: Stability, Cytotoxicity, and Cost-Effectiveness Studies.

Author

Zuccari, Guendalina, Villa, Carla, Iurilli, Valentina, Barabino, Paola, Zorzoli, Alessia, Marimpietri, Danilo, Caviglia, Debora, and Russo, Eleonora

Subjects
CYTOTOXINS, AMPHOTERICIN B, CHEMICAL stability, CHILD patients, COLLOIDAL stability, SPECIALTY pharmacies
Abstract

Liposomal amphotericin B (Ambisome®) is the gold standard for the treatment and prevention of fungal infections both in the adult and pediatric populations. The lyophilized dosage form has to be reconstituted and diluted by hospital staff, but its management can be challenging due to the spontaneous tendency of amphotericin B to form aggregates with different biological activity. In this study, the colloidal stability of the liposomes and the chemical stability of amphotericin B were investigated over time at storage conditions. Three liposomal formulations of amphotericin B at 4.0 mg/mL, 2.0 mg/mL, and 0.2 mg/mL were prepared and assayed for changes regarding the dimensional distribution, zeta potential, drug aggregation state, and onset of by-products. Our analyses highlighted that the most diluted formulation, kept at room temperature, showed the greatest changes in the aggregation state of the drug and accordingly the highest cytotoxicity. These findings are clinically relevant since the lower dosages are addressed to the more vulnerable patients. Therefore, the centralization of the dilution of AmBisome® at the pharmacy is of fundamental importance for assuring patient safety, and at the same time for reducing medication waste, as we demonstrated using the cost-saving analysis of drug expense per therapy carried out at the G. Gaslini children hospital. [ABSTRACT FROM AUTHOR]

Published
2024
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4. Current and promising therapeutic options for Dravet syndrome

Author

Riva, Antonella, primary, D’Onofrio, Gianluca, additional, Amadori, Elisabetta, additional, Tripodi, Domenico, additional, Balagura, Ganna, additional, Iurilli, Valentina, additional, Vari, Maria Stella, additional, Verrotti, Alberto, additional, and Striano, Pasquale, additional

Published
2022
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5. SURG-07. The impact of early targeted therapy on the neurosurgical approach to pediatric low-grade glioma

Author

Piatelli, Gianluca, primary, Pavanello, Marco, additional, Piccolo, Gianluca, additional, Rossi, Andrea, additional, Garrè, Maria Luisa, additional, De Marco, Patrizia, additional, Iurilli, Valentina, additional, Antonelli, Manila, additional, Gaggero, Gabriele, additional, Caruggi, Samuele, additional, Verrico, Antonio, additional, Crocco, Marco, additional, and Milanaccio, Claudia, additional

Published
2022
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6. LGG-34. Nephrological impact of BRAF inhibitors in a pediatric population of central nervous system tumors: a single institution experience

Author

Verrico, Antonio, primary, Crocco, Marco, additional, La Porta, Edoardo, additional, Angeletti, Andrea, additional, Verrina, Enrico, additional, Iurilli, Valentina, additional, Piatelli, Gianluca, additional, Piccolo, Gianluca, additional, Milanaccio, Claudia, additional, and Garrè, Maria Luisa, additional

Published
2022
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7. LGG-35. Dyslipidemia in children treated with BRAF inhibitors for brain tumor, a new side effect? A single center retrospective study

Author

Crocco, Marco, primary, Verrico, Antonio, additional, Milanaccio, Claudia, additional, Piccolo, Gianluca, additional, Gaggero, Gabriele, additional, De Marco, Patrizia, additional, Iurilli, Valentina, additional, Profio, Sonia Di, additional, Calevo, Maria Grazia, additional, Casalini, Emilio, additional, and Iorgi, Natascia Di, additional

Published
2022
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9. Dyslipidemia in Children Treated with a BRAF Inhibitor for Low-Grade Gliomas: A New Side Effect?

Author

Crocco, Marco, primary, Verrico, Antonio, additional, Milanaccio, Claudia, additional, Piccolo, Gianluca, additional, De Marco, Patrizia, additional, Gaggero, Gabriele, additional, Iurilli, Valentina, additional, Di Profio, Sonia, additional, Malerba, Federica, additional, Panciroli, Marta, additional, Giordano, Paolo, additional, Calevo, Maria Grazia, additional, Casalini, Emilio, additional, Di Iorgi, Natascia, additional, and Garrè, Maria Luisa, additional

Published
2022
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12. LGG-55. OUTCOME OF BRAF V600E PEDIATRIC GLIOMAS TREATED WITH TARGETED BRAF INHIBITION

Author

Nobre, Liana, primary, Zapotocky, Michal, additional, Ramaswamy, Vijay, additional, Ryall, Scott, additional, Bennet, Julie, additional, Alderete, Daniel, additional, Guill, Julia Balaguer, additional, Baroni, Lorena, additional, Bartels, Ute, additional, Bavle, Abhishek, additional, Bornhorst, Miriam, additional, Boue’, Daniel R, additional, Canete, Adela, additional, Chintagumpala, Murali, additional, Coven, Scott L, additional, Cruz, Ofelia, additional, Dahiya, Sonika, additional, Dirks, Peter, additional, Dunkel, Ira J, additional, Eisenstat, David, additional, Conter, Cecile Faure, additional, Finch, Elizabeth, additional, Finlay, Jonathan L, additional, Frappaz, Didier, additional, Garre, Maria Luisa, additional, Gauvain, Karen, additional, Bechensteen, Anne Grete, additional, Hansford, Jordan R, additional, Harting, Inga, additional, Hauser, Peter, additional, Hazrati, Lili-Naz, additional, Huang, Annie, additional, Injac, Sarah G, additional, Iurilli, Valentina, additional, Karajannis, Matthias, additional, Kaur, Gurcharanjeet, additional, Kyncl, Martin, additional, Krskova, Lenka, additional, Laperriere, Normad, additional, Larouche, Valerie, additional, Lassaletta, Alvaro, additional, Leary, Sarah, additional, Lin, Frank, additional, Mascelli, Samantha, additional, McKeown, Tara, additional, Milde, Till, additional, Madrid, Andres Morales La, additional, Morana, Giovanni, additional, Morse, Helena, additional, Mushtaq, Naureen, additional, Osorio, Diana S, additional, Packer, Roger, additional, Pavelka, Zdenek, additional, Quiroga-Cantero, Eduardo, additional, Rutka, James, additional, Sabel, Magnus, additional, Salgado, Duarte, additional, Solano, Palma, additional, Sterba, Jaroslav, additional, Su, Jack, additional, Sumerauer, David, additional, Taylor, Michael D, additional, Toledano, Helen, additional, Tsang, Derek S, additional, Fernandes, Mariana Valente, additional, van Landeghem, Frank, additional, van Tilburg, Cornelis M, additional, Wilson, Bev, additional, Witt, Olaf, additional, Zamecbik, Josef, additional, Bouffet, Eric, additional, Hawkins, Cynthia, additional, and Tabori, Uri, additional

Published
2020
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13. Outcomes of BRAF V600E Pediatric Gliomas Treated With Targeted BRAF Inhibition

Author

Nobre, Liana, primary, Zapotocky, Michal, additional, Ramaswamy, Vijay, additional, Ryall, Scott, additional, Bennett, Julie, additional, Alderete, Daniel, additional, Balaguer Guill, Julia, additional, Baroni, Lorena, additional, Bartels, Ute, additional, Bavle, Abhishek, additional, Bornhorst, Miriam, additional, Boue, Daniel R., additional, Canete, Adela, additional, Chintagumpala, Murali, additional, Coven, Scott L., additional, Cruz, Ofelia, additional, Dahiya, Sonika, additional, Dirks, Peter, additional, Dunkel, Ira J., additional, Eisenstat, David, additional, Faure Conter, Cecile, additional, Finch, Elizabeth, additional, Finlay, Jonathan L., additional, Frappaz, Didier, additional, Garre, Maria Luisa, additional, Gauvain, Karen, additional, Bechensteen, Anne Grete, additional, Hansford, Jordan R., additional, Harting, Inga, additional, Hauser, Peter, additional, Hazrati, Lili-Naz, additional, Huang, Annie, additional, Injac, Sarah G., additional, Iurilli, Valentina, additional, Karajannis, Matthias, additional, Kaur, Gurcharanjeet, additional, Kyncl, Martin, additional, Krskova, Lenka, additional, Laperriere, Normand, additional, Larouche, Valerie, additional, Lassaletta, Alvaro, additional, Leary, Sarah, additional, Lin, Frank, additional, Mascelli, Samantha, additional, McKeown, Tara, additional, Milde, Till, additional, Morales La Madrid, Andres, additional, Morana, Giovanni, additional, Morse, Helena, additional, Mushtaq, Naureen, additional, Osorio, Diana S., additional, Packer, Roger, additional, Pavelka, Zdenek, additional, Quiroga-Cantero, Eduardo, additional, Rutka, James, additional, Sabel, Magnus, additional, Salgado, Duarte, additional, Solano, Palma, additional, Sterba, Jaroslav, additional, Su, Jack, additional, Sumerauer, David, additional, Taylor, Michael D., additional, Toledano, Helen, additional, Tsang, Derek S., additional, Valente Fernandes, Mariana, additional, van Landeghem, Frank, additional, van Tilburg, Cornelis M., additional, Wilson, Bev, additional, Witt, Olaf, additional, Zamecnik, Josef, additional, Bouffet, Eric, additional, Hawkins, Cynthia, additional, and Tabori, Uri, additional

Published
2020
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14. LGG-16. PREDICTORS OF OUTCOME IN BRAF-V600E PEDIATRIC GLIOMAS TREATED WITH BRAF INHIBITORS: A REPORT FROM THE PLGG TASKFORCE

Author

Nobre, Liana, primary, Zapotocky, Michal, additional, Ryall, Scott, additional, Stucklin, Ana Guerreiro, additional, Bennett, Julie, additional, Baroni, Lorena, additional, Sumerauer, David, additional, Zamecnik, Josef, additional, Krskova, Lenka, additional, Misove, Adela, additional, Pavelka, Zdenek, additional, Sterba, Jaroslav, additional, Cruz, Ofelia, additional, La Madrid, Andres Morales, additional, Solano, Palma, additional, Quiroga-Cantero, Eduardo, additional, Canete, Adela, additional, Guill, Julia Balaguer, additional, Garre, Maria Luisa, additional, Mascelli, Samatha, additional, Iurilli, Valentina, additional, Hauser, Peter, additional, Frappaz, Didier, additional, Conter, Cecile Faure, additional, Hansford, Jordan, additional, Amayiri, Nisreen, additional, Morse, Helena, additional, Sabel, Magnus, additional, Bechensteen, Anne Grete, additional, Su, Jack, additional, Chintagumpala, Murali, additional, Karajannis, Matthias, additional, Kaur, Gurcharanjeet, additional, Finlay, Jonathan, additional, Osorio, Diana, additional, Coven, Scott, additional, Eisenstat, David, additional, Wilson, Bev, additional, Landeghem, Frank Van, additional, Toledano, Helen, additional, Dahiya, Sonika, additional, Gauvain, Karen, additional, Leary, Sarah, additional, Nicolaides, Theodore, additional, Finch, Elisabeth, additional, Mueller, Sabine, additional, Levy, Jean Mulcahy, additional, Foreman, Nicholas, additional, Ellison, David, additional, Lassaletta, Alvaro, additional, Larouche, Valerie, additional, Mushtaq, Naureen, additional, Milde, Till, additional, Vantilburg, Cornelis, additional, Witt, Olaf, additional, Salgado, Duarte, additional, Harting, Inga, additional, Bornhorst, Miriam, additional, Packer, Roger, additional, Fernandes, Mariana, additional, Injac, Sarah, additional, Bavle, Abhi, additional, Alderete, Daniel, additional, Ramaswamy, Vijay, additional, Taylor, Michael, additional, Dirks, Peter, additional, McKeown, Tara, additional, Bartels, Ute, additional, Bouffet, Eric, additional, Hawkins, Cynthia, additional, and Tabori, Uri, additional

Published
2019
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15. A 5-center experience with intrathecal administration of nusinersen in SMA1 in Italy letter to the editor of european journal of pediatric neurology regarding the manuscript “single-center experience with intrathecal administration of nusinersen in children with spinal muscular atrophy type 1” written by pechmann and colleagues”

Author

Sansone, V.A., primary, Pane, M., additional, Messina, S., additional, Bruno, C., additional, D'Amico, A., additional, Albamonte, E., additional, Catteruccia, M., additional, Sframeli, M., additional, Pedemonte, M., additional, Vita, G., additional, Bertini, E., additional, Mercuri, E., additional, Leone, Daniela, additional, de Sanctis, Roberto, additional, Forcina, Nicola, additional, Piastra, Marco, additional, Genovese, Orazio, additional, Pedicelli, Alessandro, additional, Versaci, Antonio, additional, Rulli, Imma, additional, Gitto, Eloisa, additional, Faraone, Cristina, additional, La Foresta, Stefania, additional, Macrì, Maria, additional, Colia, Giulia, additional, Bonetti, Anna Maria, additional, Carlesi, Adelina, additional, Cutrera, Renato, additional, Chiarini, Maria Beatrice, additional, Ferretti, Marta, additional, Garaventa, Alberto, additional, Montobbio, Giovanni, additional, Gandolfo, Carlo, additional, Iurilli, Valentina, additional, Tacchetti, Paola, additional, Bobeica, Emilia, additional, D'Agostino, Alessia, additional, Pirola, Alice, additional, Lupone, Sara, additional, De Mattia, Elisa, additional, Falcier, Elisa, additional, Rao, Fabrizio, additional, Casiraghi, Jacopo, additional, Salmin, Francesca, additional, Grandi, Cristina, additional, Fedeli, Fausto, additional, Mancini, Luca, additional, Stoia, Paolo, additional, Heinen, Maurizio, additional, Cozzi, Valeria, additional, Travaglia, Beatrice, additional, and Mizzotti, Emma, additional

Published
2018
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16. Expanded access program with Nusinersen in SMA type I in Italy: Strengths and pitfalls of a successful experience

Author

Messina, Sonia, primary, Pane, Marika, additional, Sansone, Valeria, additional, Bruno, Claudio, additional, Catteruccia, Michela, additional, Vita, Giuseppe, additional, Palermo, Concetta, additional, Albamonte, Emilio, additional, Pedemonte, Marina, additional, Bertini, Enrico, additional, Binetti, Luca, additional, Mercuri, Eugenio, additional, Lauro, Daniela, additional, Pallara, Anita, additional, Spinoglio, Simona, additional, Solinas, Maria Letizia, additional, Zappa, Grazia, additional, Penno, Francesca, additional, Ponzanelli, Cristina, additional, Casiraghi, Jacopo, additional, Villanova, Marcello, additional, Tiziano, Danilo, additional, Mandelli, Anna, additional, Mastella, Chiara, additional, Fontana, Alberto, additional, Ambrosini, Anna, additional, Leone, Daniela, additional, de Sanctis, Roberto, additional, Forcina, Nicola, additional, Piastra, Marco, additional, Genovese, Orazio, additional, Pedicelli, Alessandro, additional, Sframeli, Maria, additional, Versaci, Antonio, additional, Rulli, Imma, additional, Gitto, Eloisa, additional, Faraone, Cristina, additional, La Foresta, Stefania, additional, Macrì, Maria, additional, D'Amico, Adele, additional, Colia, Giulia, additional, Bonetti, Anna Maria, additional, Carlesi, Adelina, additional, Cutrera, Renato, additional, Chiarini, Maria Beatrice, additional, Ferretti, Marta, additional, Garaventa, Alberto, additional, Montobbio, Giovanni, additional, Gandolfo, Carlo, additional, Iurilli, Valentina, additional, Tacchetti, Paola, additional, Bobeica, Emilia, additional, D'Agostino, Alessia, additional, Pirola, Alice, additional, Luppone, Sara, additional, De Mattia, Elisa, additional, Falcier, Elisa, additional, Rao, Fabrizio, additional, Fedeli, Fausto, additional, Mancini, Luca, additional, Stoia, Paolo, additional, Heinen, Maurizio, additional, Cozzi, Valeria, additional, Travaglia, Beatrice, additional, and Mizzotti, Emma, additional

Published
2017
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17. Expanded access program with Nusinersen in SMA type I in Italy: Strengths and pitfalls of a successful experience

Author

Lauro, Daniela, Pallara, Anita, Spinoglio, Simona, Solinas, Maria Letizia, Zappa, Grazia, Penno, Francesca, Ponzanelli, Cristina, Casiraghi, Jacopo, Villanova, Marcello, Tiziano, Danilo, Mandelli, Anna, Mastella, Chiara, Fontana, Alberto, Ambrosini, Anna, Leone, Daniela, de Sanctis, Roberto, Forcina, Nicola, Piastra, Marco, Genovese, Orazio, Pedicelli, Alessandro, Sframeli, Maria, Versaci, Antonio, Rulli, Imma, Gitto, Eloisa, Faraone, Cristina, La Foresta, Stefania, Macrì, Maria, D'Amico, Adele, Colia, Giulia, Bonetti, Anna Maria, Carlesi, Adelina, Cutrera, Renato, Chiarini, Maria Beatrice, Ferretti, Marta, Garaventa, Alberto, Montobbio, Giovanni, Gandolfo, Carlo, Iurilli, Valentina, Tacchetti, Paola, Bobeica, Emilia, D'Agostino, Alessia, Pirola, Alice, Luppone, Sara, De Mattia, Elisa, Falcier, Elisa, Rao, Fabrizio, Fedeli, Fausto, Mancini, Luca, Stoia, Paolo, Heinen, Maurizio, Cozzi, Valeria, Travaglia, Beatrice, Mizzotti, Emma, Messina, Sonia, Pane, Marika, Sansone, Valeria, Bruno, Claudio, Catteruccia, Michela, Vita, Giuseppe, Palermo, Concetta, Albamonte, Emilio, Pedemonte, Marina, Bertini, Enrico, Binetti, Luca, and Mercuri, Eugenio

Published
2017
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18. OUTCOME OF BRAF V600E PEDIATRIC GLIOMAS TREATED WITH TARGETED BRAF INHIBITION

Author

Nobre, Liana, Zapotocky, Michal, Ramaswamy, Vijay, Ryall, Scott, Bennet, Julie, Alderete, Daniel, Balaguer Guill, Julia, Baroni, Lorena, Bartels, Ute, Bavle, Abhishek, Bornhorst, Miriam, Boue, Daniel R., Canete, Adela, Chintagumpala, Murali, Coven, Scott L., Cruz, Ofelia, Dahiya, Sonika, Dirks, Peter, Dunkel, Ira J., Eisenstat, David, Conter, Cecile Faure, Finch, Elizabeth, Finlay, Jonathan L., Frappaz, Didier, Garre, Maria Luisa, Gauvain, Karen, Bechensteen, Anne Grete, Hansford, Jordan R., Harting, Inga, Hauser, Peter, Hazrati, Lili-Naz, Huang, Annie, Injac, Sarah G., Iurilli, Valentina, Karajannis, Matthias, Kaur, Gurcharanjeet, Kyncl, Martin, Krskova, Lenka, Laperriere, Normad, Larouche, Valerie, Lassaletta, Alvaro, Leary, Sarah, Lin, Frank, Mascelli, Samantha, Mckeown, Tara, Till Milde, Morales La Madrid, Andres, Morana, Giovanni, Morse, Helena, Mushtaq, Naureen, Osorio, Diana S., Packer, Roger, Pavelka, Zdenek, Quiroga-Cantero, Eduardo, Rutka, James, Sabel, Magnus, Salgado, Duarte, Solano, Palma, Sterba, Jaroslav, Su, Jack, Sumerauer, David, Taylor, Michael D., Toledano, Helen, Tsang, Derek S., Fernandes, Mariana Valente, Landeghem, Frank, Tilburg, Cornelis M., Wilson, Bev, Witt, Olaf, Zamecbik, Josef, Bouffet, Eric, Hawkins, Cynthia, and Tabori, Uri

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