Search

This essay examines Benjamin Robert Haydon's neglected transcripts of John Keats's letters (1845–46). Haydon copied these letters to aid the writing of Richard Monckton Milnes's first biography of the poet, Life, Letters, and Literary Remains, of John Keats (1848). For reasons unknown, however, subsequent critics and scholars have consigned the transcript copies to oblivion without making available their full text (some of which is omitted in Milnes's Life). In addition to the transcripts themselves, Haydon's annotations offer a new insight into his close relationship with Keats. The material will be of interest to many Keats scholars, especially those who wish to explore the complexities of his reception in the mid-nineteenth century and beyond, as well as the friendship between the poet and the painter. [ABSTRACT FROM AUTHOR]

Background: Vertebral compression fractures, which are commonly associated with older age and osteoporotic fractures, have an increased risk of re‐fracture. Therefore, improving balance is important to prevent falls. The minimal important change (MIC) has been recommended for interpreting clinically meaningful changes in rating scales. The MIC of the Berg Balance Scale (BBS) for use in older women with vertebral compression fractures has not been established. Objective: To identify the MIC of the BBS that can be used in older women with vertebral compression fractures using predictive modeling methods and the receiver‐operating characteristic (ROC)–based method. Design: A retrospective longitudinal multicenter study. Patients: Sixty older women (mean age ± standard deviation: 84.1 ± 7.0 years) with vertebral compression fractures who were unable to ambulate independently on a level surface. Methods: A change of one point in the Functional Ambulation Category (FAC) was used as an anchor to calculate the MIC of the BBS based on the change between admission and discharge. We calculated the MIC for the women whose FAC score improved by ≥1 point. We used three anchor‐based methods to examine the MIC: the ROC‐based method (MICROC), the predictive modeling method (MICpred), and the MICpred‐based method adjusted by the rate of improvement and reliability of transition (MICadj). Results: Thirty‐nine women comprised the "important change" group based on their FAC score improvement. In this group, the MICROC (95% confidence interval [CI]) value of the BBS was 10.0 points (5.5–15.5), with an area under the curve of 0.71. The MICpred (95% CI) value was 9.7 (8.1–11.0), and the MICadj (95% CI) was 7.0 (5.5–8.5) points. Conclusion: For women with vertebral compression fractures who are unable to ambulate independently, a 7.0‐point improvement in the BBS score may be a useful indicator for reducing the amount of assistance required for walking. [ABSTRACT FROM AUTHOR]

Proton-induced nuclide production cross sections for Bi at incident energies of 0.4, 1.5, and 3.0 GeV are measured with the activation method using the proton beams accelerated from the Rapid-Cycling Synchrotron of the Japan Proton Accelerator Research Complex (J-PARC). A total of 127 cross-section data are obtained. The measured data are compared with two types of Monte Carlo-based spallation models (i.e. INCL++ coupled with ABLA07 and INCL4.6 coupled with GEM), and the evaluated nuclear data library, JENDL/HE-2007. The result showed that INCL++/ABLA07 overall agrees with the experimental data, whereas INCL4.6/GEM underestimates the production of fission fragments.

For the research and development of accelerator-driven systems (ADSs) and fundamental ADS reactor physics research using the Kyoto University Critical Assembly combined with the fixed-field alternating gradient (FFAG) accelerator, we are conducting a series of experiments on double-differential neutron yields using the FFAG accelerator at Kyoto University. This paper presents an overview of the experiments together with preliminary results.

A Clinical prediction rule (CPR) for determining multi surfaces walking independence in persons with stroke has not been established. To develop a CPR for determining multi surfaces walking independence in persons with stroke. This was a multicenter retrospective analysis of 419 persons with stroke. We developed a Berg Balance Scale (BBS)-model CPR combining the BBS, comfortable walking speed (CWS) and cognitive impairment, and a Mini-Balance Evaluation Systems Test (Mini-BESTest)-model CPR combining the Mini-BESTest, CWS, and cognitive impairment. A logistic regression analysis was conducted with multi surfaces walking independence as the dependent variable and each factor as an independent variable. The identified factors were scored (0, 1) based on reported cutoff values. The CPR's accuracy was verified by the area under the curve (AUC). We used a bootstrap method internal validation and calculated the CPR's posttest probability. The logistic regression analysis showed that the BBS, CWS, and cognitive impairment were factors in the BBS model, and the Mini-BESTest was a factor in the Mini-BESTest model. The CPRs were 0–3 points for the BBS model and 0–1 points for the Mini-BESTest model. The AUCs (bootstrap mean AUC) of the CPR score were 0.89 (0.90) for the BBS model and 0.72 (0.72) for the Mini-BESTest model. The negative predictive value (negative likelihood ratio) was 97% (0.054) for CPR scores < 2 for the BBS model and 94% (0.060) for CPR scores < 1 for the Mini-BESTest model. The CPR developed herein is useful for determining multi surfaces walking independence. [ABSTRACT FROM AUTHOR]

Balance impairment occurs after a hip fracture, but the characteristics of the impairment are not clear. To investigate the uni-dimensionality, fit statistics, and item difficulty of the Berg Balance Scale (BBS) in older adults with hip fracture by conducting a Rasch analysis. This was an observational cross-sectional study. The 254 participants were all ≥ 65 years old and had been hospitalized for rehabilitation after a unilateral hip fracture incurred during a fall. We collected their BBS scores at the time of hospital discharge and conducted a Rasch analysis to examine the uni-dimensionality, fit statistics, and item difficulty. The principal component analysis (PCA) of the Rasch model demonstrated that the BBS is uni-dimensional. The information-weighted mean square (MnSq) fit statistic was within the range of fit criteria for all items. The underfit item of the outlier-sensitive MnSq fit statistics was "Standing unsupported eyes closed" with the MnSq of 2.06. The difficult items were in order of logits: "Standing on one leg" (logits = 4.01); "Step tool" (logits = 2.74); and "Turn 360°" (logits = 2.61). The BBS is uni-dimensional and conforms with the Rasch model. The BBS most difficult items for older adults with a hip fracture required one-legged support and dynamic balance. [ABSTRACT FROM AUTHOR]

Background Several hip fracture clinical prediction models have been developed. We conducted this study to (i) map outcomes used in clinical prediction models for hip fracture, (ii) identify the domains and instruments of predictors, and (iii) assess the risk of bias. Methods We performed systematic searches of studies published from June 2002 to June 2023 in the PubMed, Cochrane Library, CINAHL, CiNii, and Ichushi databases. After the relevant articles were identified, we performed the data extraction and bias risk assessment. We used the Prediction Study Risk Of Bias Assessment Tool (PROBAST) to assess each study's risk of bias. Outcome mapping was performed for the core outcome set of hip fractures. Qualitative synthesis and the PROBAST evaluation were performed on other-than-mortality core outcomes, which are difficult to target in rehabilitation. Results We screened 3 206 studies for eligibility; 45 studies were included in the outcome mapping, and 10 studies were included in the qualitative synthesis. Outcomes included mortality (n = 35), mobility (n = 8), and activities of daily living (n = 2). No clinical prediction models had pain or health-related quality of life as an outcome. Predictors were reported in 8 domains and 38 measures. The PROBAST evaluation showed a high risk of bias in all 10 studies that were eligible for a qualitative synthesis. Conclusions The clinical prediction models had only mortality, mobility, and activities of daily living as outcomes. The development of clinical prediction models with pain and health-related quality of life as outcomes is necessary. Clinical prediction models overcoming the risk of bias identified in this study are also needed. [ABSTRACT FROM AUTHOR]

For damage estimation of structural material in the accelerator facility, displacement per atom (DPA) is widely employed as an index of the damage calculated based on the displacement cross section obtained with the calculation model. Although the DPA is employed as the standard, the experimental data of displacement cross section are scarce for a proton in the energy region above 20 MeV. Among the calculation models, the difference exists about 8 times so that experimental data of the displacement cross section is crucial to validate the model. To obtain the displacement cross section, we conducted the experiment in J-PARC. As a preliminary result, the displacement cross section of copper was successfully obtained for 3-GeV proton. The present results showed that the widely utilized the Norgertt-Robinson-Torrens (NRT) model overestimates the cross section as suggested by the previous experiment for protons with lower energy.

For the Accelerator-Driven nuclear transmutation System (ADS), nuclide production yield estimation in a lead-bismuth target is important to manage the target. However, experimental data of nuclide production yield by spallation and high-energy fission reactions are scarce. In order to obtain the experimental data, an experiment in J-PARC using natPb and 209Bi samples were carried out. The samples were thin foils with about 0.1 mm thick and 25 mm × 25 mm square and were irradiated with protons at kinematic energy points of 0.4GeV, 2.2GeV, and 3.0 GeV. After the irradiation, the nuclide production cross section was determined by spectroscopic measurement of decay gamma-rays from the samples with HPGe detectors. In this paper, 14 nuclide production cross sections for lead and bismuth were obtained. They were compared with the calculated cross sections with various models and the evaluated one.

In order to understand the current status of the predictive performance of spallation models and issues towards further improvement, a comprehensive study of the proton-induced spallation product yields was conducted. In this study, four kinds of the latest spallation models (i.e. INCL++/ABLA07, INCL++/GEMINI++, INCL4.6/GEM, and CEM03.03), utilized in Monte Carlo particle transport calculation, are employed, and six pieces of cross section data measured at GSI, RIKEN, and J-PARC are used for comparison. As a result, the INCL++/ABLA07 calculations are in general agreement with the GSI and RIKEN experimental data, whereas some discrepancies are observed especially in the comparisons with the J-PARC experiments. Finally, several key issues inherent in each spallation model are described.

To identify the Berg Balance Scale (BBS) values that can be used to discriminate the use of a walking aid and the BBS sub-items that reveal the differences in the use of walking aids among hospitalized older adults with a hip fracture The cases of 77 older adults (age 80.8 ± 7.5 years) with a hip fracture who were able to walk independently in the hospital were retrospectively analyzed. A receiver operating characteristic curve (AUC) analysis was used to identify BBS scores that optimized the identification of subjects with different levels of aids. The BBS sub-items identifying differing among the walking aids were identified by a classification and regression tree analysis The BBS scores were highest for no aid, a cane, and a walker, in that order. The ability to walk without an aid and the ability to walk without a walker showed moderate AUCs (0.824 and 0.865) with cutoff values of 51.5 and 45.5 points, respectively. The sub-items identified were Turning 360° (4 vs. < 4 points) as the best discriminator for using/not using a cane and Stool Stepping (≥ 2 vs. < 2 points) for using a cane or walker The BBS is useful for determining whether to discontinue the use of a walker in individuals with a hip fracture. [ABSTRACT FROM AUTHOR]

This paper presents a nuclear data sensitivity and uncertainty analysis of the effective delayed neutron fraction βeff for critical and subcritical cores of the MYRRHA reactor using the continuous-energy Monte Carlo N-Particle transport code MCNP. The βeff sensitivities are calculated by the modified k-ratio method proposed by Chiba. Comparing the βeff sensitivities obtained with different scaling factors a introduced by Chiba shows that a value of a = 20 is the most suitable for the uncertainty quantification of βeff. Using the calculated βeff sensitivities and the JENDL-4.0u covariance data, the βeff uncertainties for the critical and subcritical cores are determined to be 2.2 ± 0.2% and 2.0 ± 0.2%, respectively, which are dominated by delayed neutron yield of 239Pu and 238U.