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Your search keyword '"Iwamoto, Masahiko"' showing total 21 results
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21 results on '"Iwamoto, Masahiko"'

10. Association of insulin treatment with gastric residue during an esophagogastroduodenoscopy.

Author

Kobori, Toshiko, Onishi, Yukiko, Iwamoto, Masahiko, Kubota, Tetsuya, Kikuchi, Takako, Tahara, Tazu, Takao, Toshiko, Fujiwara, Hiroaki, Yoshida, Yoko, and Kasuga, Masato

Subjects
INSULIN therapy, DIGESTIVE system endoscopic surgery, GLYCOSYLATED hemoglobin, PROPORTIONAL hazards models, TYPE 2 diabetes, GLYCEMIC control
Abstract

The purpose of this study was to investigate the association of glycemic control and diabetes treatment to gastric residue observed during an esophagogastroduodenoscopy. Among 6,592 individuals who had esophagogastroduodenoscopy at our clinic between 2003 and 2019, we retrospectively and longitudinally identified those who had gastric residue during an esophagogastroduodenoscopy. Other data collected were age, sex, diagnosis of diabetes, glycated hemoglobin and diabetes medication. Cox proportional hazards models were used to assess the association of these data with the occurrence of gastric residue. To the best of our knowledge, this is the first retrospective cohort study finding that undergoing insulin treatment is a risk factor for gastric residue independent of age, sex and diabetes or glycated hemoglobin. [ABSTRACT FROM AUTHOR]

Published
2022
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11. Diabetes management by either telemedicine or clinic visit improved glycemic control during the coronavirus disease 2019 pandemic state of emergency in Japan.

Author

Onishi, Yukiko, Yoshida, Yoko, Takao, Toshiko, Tahara, Tazu, Kikuchi, Takako, Kobori, Toshiko, Kubota, Tetsuya, Shimmei, Asuka, Iwamoto, Masahiko, and Kasuga, Masato

Subjects
COVID-19 pandemic, CORONAVIRUS diseases, GLYCEMIC control, COVID-19, GLYCOSYLATED hemoglobin, DIABETES
Abstract

The purpose of this retrospective cohort study at a Tokyo diabetes clinic was to evaluate the effect of telemedicine and clinic visit on glycated hemoglobin (HbA1c) during the coronavirus disease 2019 state of emergency. The effect of telemedicine and clinic visit during the emergency period on the post‐emergency measured HbA1c was evaluated by multiple regression models and logistic regression models adjusted for age, sex, type of diabetes, pre‐emergency HbA1c and body mass index, and body mass index change during the emergency period. Among 2,727 patients who visited the clinic before and after the emergency period, the interval between clinic visits during the emergency period was significantly associated with HbA1c improvement. Telemedicine and clinic visit were independently associated with HbA1c improvement when pre‐emergency HbA1c was ≥7%. In conclusion, clinic visit and telemedicine during the coronavirus disease 2019 emergency period were both independently effective in HbA1c improvement in Japanese diabetes patients who had insufficient HbA1c control. [ABSTRACT FROM AUTHOR]

Published
2022
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12. Association between tear and blood glucose concentrations: Random intercept model adjusted with confounders in tear samples negative for occult blood

Author

Aihara, Masakazu, primary, Kubota, Naoto, additional, Minami, Takahiro, additional, Shirakawa, Rika, additional, Sakurai, Yoshitaka, additional, Hayashi, Takanori, additional, Iwamoto, Masahiko, additional, Takamoto, Iseki, additional, Kubota, Tetsuya, additional, Suzuki, Ryo, additional, Usami, Satoshi, additional, Jinnouchi, Hideaki, additional, Aihara, Makoto, additional, Yamauchi, Toshimasa, additional, Sakata, Toshiya, additional, and Kadowaki, Takashi, additional

Published
2020
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13. Association between tear and blood glucose concentrations: Random intercept model adjusted with confounders in tear samples negative for occult blood.

Author

Aihara, Masakazu, Kubota, Naoto, Minami, Takahiro, Shirakawa, Rika, Sakurai, Yoshitaka, Hayashi, Takanori, Iwamoto, Masahiko, Takamoto, Iseki, Kubota, Tetsuya, Suzuki, Ryo, Usami, Satoshi, Jinnouchi, Hideaki, Aihara, Makoto, Yamauchi, Toshimasa, Sakata, Toshiya, and Kadowaki, Takashi

Subjects
BLOOD sugar, BLOOD sugar monitoring, GLYCOSYLATED hemoglobin, BLOOD testing, GLUCOSE
Abstract

Aims/Introduction: To prevent diabetic complications, strict glucose control and frequent monitoring of blood glucose levels with invasive methods are necessary. We considered the monitoring of tear glucose levels might be a possible method for non‐invasive glucose monitoring. To develop tear glucose monitoring for clinical application, we investigated the precise correlation between the blood and tear glucose concentrations. Materials and Methods: A total of 10 participants and 20 participants with diabetes were admitted, and blood and tear samples were collected. Before statistical analysis, we eliminated tear samples contaminated with blood. We observed the daily blood and tear glucose dynamics, and carried out a random intercept model analysis to examine the association between the blood and tear glucose concentrations. Results: Tear occult blood tests showed that the tear glucose concentrations and their variation increased in both participants with and without diabetes as contamination of blood increased. In both participants with and without diabetes, fluctuations of the plasma glucose concentrations were observed depending on the timing of collection of the samples, and the dynamics of the tear glucose concentrations paralleled those of the plasma glucose concentrations. The random intercept model analysis showed a significant association between the plasma and tear glucose concentrations in participants with diabetes (P < 0.001). This association still existed even after adjusting for the glycated hemoglobin levels and the prandial state (P < 0.001). Conclusions: It is important to eliminate the tear samples contaminated with blood. Tear glucose monitoring might be a reliable and non‐invasive substitute method for monitoring the blood glucose concentrations for diabetes patients, irrespective of glycated hemoglobin levels and timing of sample collection. [ABSTRACT FROM AUTHOR]

Published
2021
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15. SGLT2阻害薬の抗動脈硬化作用 : モデル動物を用いた検討

Author

Iwamoto, Masahiko

Abstract

学位の種別: 課程博士, 審査委員会委員 : （主査）東京大学教授 南学 正臣, 東京大学准教授 吉内 一浩, 東京大学准教授 柿木 章伸, 東京大学准教授 加藤 聡, 東京大学講師 伊地知 秀明

Published
2016

17. Tofogliflozin Improves Insulin Resistance in Skeletal Muscle and Accelerates Lipolysis in Adipose Tissue in Male Mice

Author

Obata, Atsushi, primary, Kubota, Naoto, primary, Kubota, Tetsuya, primary, Iwamoto, Masahiko, primary, Sato, Hiroyuki, primary, Sakurai, Yoshitaka, primary, Takamoto, Iseki, primary, Katsuyama, Hisayuki, primary, Suzuki, Yoshiyuki, primary, Fukazawa, Masanori, primary, Ikeda, Sachiya, primary, Iwayama, Kaito, primary, Tokuyama, Kumpei, primary, Ueki, Kohjiro, primary, and Kadowaki, Takashi, primary

Published
2015
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19. TCF7L2 in mouse pancreatic beta cells plays a crucial role in glucose homeostasis by regulating beta cell mass

Author

Takamoto, Iseki, primary, Kubota, Naoto, additional, Nakaya, Keizo, additional, Kumagai, Katsuyoshi, additional, Hashimoto, Shinji, additional, Kubota, Tetsuya, additional, Inoue, Mariko, additional, Kajiwara, Eiji, additional, Katsuyama, Hisayuki, additional, Obata, Atsushi, additional, Sakurai, Yoshitaka, additional, Iwamoto, Masahiko, additional, Kitamura, Tadahiro, additional, Ueki, Kohjiro, additional, and Kadowaki, Takashi, additional

Published
2013
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