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Colorectal cancer screening has been shown to prevent or detect early colorectal cancer and reduce mortality; yet, adherence to screening recommendations remains low, particularly in rural settings.RCT.Adults (n=7,812) aged 50-75 years and due for colorectal cancer screening in a largely rural health system were randomly assigned to either the intervention (n=3,906) or the control (n=3,906) group in September 2016, with analysis following through 2018.A mailed motivational messaging screening reminder letter with an option to call and request a free at-home fecal immunochemical screening test (intervention) or the standard invitation letter detailing that the individual was due for screening (control). Multifaceted motivational messaging emphasized colorectal cancer preventability and the ease and affordability of screening, and communicated a limited supply of test kits.Colorectal cancer screening participation within 6 months after mailed invitation was ascertained from the electronic medical record.Colorectal cancer screening participation was significantly improved in the intervention (30.1%) vs the usual care control group (22.5%; p0.001). Individuals randomized to the intervention group had 49% higher odds of being screened over follow-up than those randomized to the control group (OR=1.49, 95% CI=1.34, 1.65). A total of 13.2 screening invitations were needed to accomplish 1 additional screening over the usual care. Of the 233 fecal immunochemical test kits mailed to participants, 154 (66.1%) were returned, and 18 (11.7%) tested positive.A mailed motivational messaging letter with a low-cost screening alternative increased colorectal cancer screening in this largely rural community with generally poor adherence to screening recommendations. Mailed colorectal cancer screening reminders using motivational messaging may be an effective method for increasing screening and reducing rural colorectal cancer disparities.

Many modern and future particle accelerators employ high gradient superconducting RF (SRF) to generate beams of high energy, high intensity and high brightness for research in high energy and nuclear physics, basic energy sciences, etc. In this paper we report the record performance large-scale SRF system with average beam accelerating gradient matching the ILC specification of 31.5MV/m. Design of the eight cavity 1.3 GHz SRF cryomodule, its performance without the beam and results of the system commissioning with high intensity electron beam at FAST (Fermilab Accelerator Science and Technology) facility are presented. We also briefly discuss opportunities for further beam studies and tests at FAST including those on even higher gradient and more efficient SRF acceleration., Comment: 18 pages, 9 figures

The Integrable Optics Test Accelerator (IOTA) is a storage ring for advanced beam physics research currently being built and commissioned at Fermilab. It will operate with protons and electrons using injectors with momenta of 70 and 150 MeV/c, respectively. The research program includes the study of nonlinear focusing integrable optical beam lattices based on special magnets and electron lenses, beam dynamics of space-charge effects and their compensation, optical stochastic cooling, and several other experiments. In this article, we present the design and main parameters of the facility, outline progress to date and provide the timeline of the construction, commissioning and research. The physical principles, design, and hardware implementation plans for the major IOTA experiments are also discussed., Comment: 42 pages, 31 figures

To prepare a beam generation device for Fermilab's future Recycler Electron Cooling system, an experimental set-up with a simplified beam line has been commissioned at Fermilab. Stable operation was achieved at an electron energy of 3.5 MeV and a DC beam current of up to 0.5 A. The main reason for interruptions of the operation was found to be microsecond long bursts of the cathode current. While the frequency of the interruptions is determined primarily by a flow of secondary ions, the resulting reduction in the duty factor depends on the beam optics, the protection systems, and the tube electric field strength.

A prototype of a 4.3-MeV electron cooling system has been assembled at Fermilab as part of the on-going R&D program in high-energy electron cooling. This electron cooler prototype will not demonstrate the actual cooling but it would allow to determine if the electron beam properties are suitable for antiproton beam cooling. An electron beam is accelerated by a 5-MV Pelletron (Van de Graaff type) accelerator and transported to a prototype cooling section. The cooling would take place in a 20-m long solenoid flanked on both sides by supply and return beam-lines—a total of 60 m of transport channel. This paper describes the status of the electron cooling R&D program.

Fermilab is the nation’s particle physics laboratory, supported by the DOE Office of High Energy Physics (OHEP). Fermilab is a world leader in accelerators, with a demonstrated track-record— spanning four decades—of excellence in accelerator science and technology. We describe the significant opportunity to complete, in a highly leveraged manner, a unique accelerator research facility that supports the broad strategic goals in accelerator science and technology within the OHEP. While the US accelerator-based HEP program is oriented toward the Intensity Frontier, which requires modern superconducting linear accelerators and advanced highintensity storage rings, there are no accelerator test facilities that support the accelerator science of the Intensity Frontier. Further, nearly all proposed future accelerators for Discovery Science will rely on superconducting radiofrequency (SRF) acceleration, yet there are no dedicated test facilities to study SRF capabilities for beam acceleration and manipulation in prototypic conditions. Finally, there are a wide range of experiments and research programs beyond particle physics that require the unique beam parameters that will only be available at Fermilab’s Advanced Superconducting Test Accelerator (ASTA). To address these needs we submit this proposal for an Accelerator R&D User Facility at ASTA. The ASTA program is based on the capability provided by an SRF linac (which provides electron beams from 50 MeV to nearly 1 GeV) and a small storage ring (with the ability to store either electrons or protons) to enable a broad range of beam-based experiments to study fundamental limitations to beam intensity and to develop transformative approaches to particle-beam generation, acceleration and manipulation which cannot be done elsewhere. It will also establish a unique resource for R&D towards Energy Frontier facilities and a test-bed for SRF accelerators and high brightness beam applications in support of the OHEP mission of Accelerator Stewardship.

Fermi National Accelerator Laboratory is constructing a superconducting 1.3 GHz cryomodule test facility located at the New Muon Lab building. The facility will be used for testing and validating cryomodule designs as well as support systems. For the initial phase of the project, a single Type III plus 1.3 GHz cryomodule will be cooled and tested using a single Tevatron style standalone refrigerator. Subsequent phases involve testing as many as two full RF units consisting of up to six 1.3 GHz cryomodules with the addition of a new cryogenic plant. The cryogenic infrastructure consists of the refrigerator system, cryogenic distribution system as well as an ambient temperature pumping system to achieve 2 K operations with supporting purification systems. A discussion of the available capacity for the various phases versus the proposed heat loads is included as well as commissioning results and testing schedule. This paper describes the plans, status and challenges of this initial phase of the New Muon Lab cryogenic system., 8 pp. Cryogenic Engineering Conference and International Cryogenic Materials Conference 28 Jun - 2 Jul 2009. Tucson, Arizona

The recent demonstration of electron cooling of antiprotons in the Recycler ring required a stable 4.3 MeV electron beam with a DC current of hundreds of mA and an angular spread in the cooling section of a fraction of a mrad. This paper describes the achieved parameters of the Fermilab cooler’s electron beam and details of operation.

The 8.9‐GeV/c Recycler antiproton storage ring is equipped with both stochastic and electron cooling systems. These cooling systems are designed to assist accumulation of antiprotons for the Tevatron collider operations. In this paper we report on an experimental demonstration of electron cooling of high‐energy antiprotons. At the time of writing this report, the Recycler electron cooling system is routinely used in collider operations. It has helped to set recent peak luminosity records.

A prototype of a 4.3-MeV electron cooling system is being assembled at Fermilab as part of the ongoing R&D program in high energy electron cooling. This electron cooler prototype will not demonstrate the actual cooling but it will allow determining if the electron beam properties are suitable for antiproton beam cooling. An electron beam is accelerated by a 5-MV Pelletron (Van de Graaff type) accelerator and transported to a prototype cooling section. The cooling will take place in a 20-m long solenoid flanked on both sides by a delivery and return beam-line - a total of 60 meters of transport channel. This paper describes the first results of commissioning this novel beam line as well as the status of the electron cooling R&D program.

The Main Injector (MI) construction schedule requires the use of several magnet installation vehicles concurrently. During the interval when MI dipoles are to be installed, both existing magnet installation vehicles will be used in the Main Ring (existing accelerator) to support machine operations. This necessitates the development of a new magnet installation system designed for use with the MI dipole magnets. Because all magnet installation vehicles will be available for MI installation following the decommissioning of the Main Ring, the system should be as inexpensive as possible. The chosen solution for MI dipole magnet installation is as follows: a tugger/towmotor (the Tevatron vehicle could be drafted) will tow the Main Injector dipoles to their installation site on dollies, then lift them slightly from the dollies and move them onto their magnet support stands. >

In order to control the beam emittance and reduce the particle losses during the transition crossing at high intensity, a conceptual design of a /spl gamma/t-jump system for the FNAL Main Injector is presented. It is a first-order system employing local dispersion inserts at existing dispersion free straight sections. The goal is to provide a jump of /spl Delta//spl gamma//sub t/ from +1 to -1 within 0.5 ms. The system consists of 8 sets of pulsed quadrupole triplets. These quads have pole tips of hyperbolic shape and thin laminations. The power supply uses a GTO as the fast switch and a resonant circuit with a 1 kHz resonant frequency. The elliptical beam tube is made of Inconel 718, which has high electrical resistivity and high strength. Details of the lattice layout and subsystems design are presented.

An important part of the Fermilab's Recycler Electron Cooling (REC) project is a recirculation test which is performed using a 5-MV electrostatic accelerator, a Pelletron, with two tubes and a simplified beam line with one 180-degree bend. The main goal of the test is to demonstrate stable operation of a 4.4-MeV, 0.5-A DC electron beam. The paper describes the set-up and the early experimental results.

The Fermilab Electron Cooling project involves interacting a 4.3 MeV, 0.5 A DC electron beam with 8.9 GeV/c antiprotons in the FNAL Recycler Ring. This interaction occurs through a 20-meter long cooling section consisting of 10 solenoid modules. This cooling process would lead to an increase in the Tevatron collider luminosity needed to support the Run IIb parameters. There are several important engineering aspects of this cooling section including: solenoid design, vacuum system design, magnetic shielding, support system, and alignment methods. Details of the engineering issues related to each of these areas will be discussed.

A 4.3-MeV electron cooling system [1] has been installed at Fermilab in the Recycler antiproton storage ring and is currently being commissioned. The cooling system is designed to assist accumulation of 8.9-GeV/c antiprotons for the Tevatron collider operations. This paper reports on the progress of the electron beam commissioning effort as well as on detailed plans of demonstrating the cooling of antiprotons.