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The purpose of this study was to evaluate volumetric and dentoskeletal changes in 21 patients with active unilateral condylar hyperplasia (AUCH) after proportional condylectomy. A split-mouth design was used: control group healthy joints (HS, healthy side) and test group affected joints (AS, affected side) (21 per group). Cone beam tomography scans were obtained at T0 (preoperative), T1 (10days after the intervention), and T2 (approximately 12 months post-surgery). The condylar unit volume (CUV), articular cavity volume (ACV), and dentoalveolar units (DAUs) were measured. CUV showed a difference of 1.12cm3 between T0 and T1, increasing 0.4cm3 between T1 and T2 on AS. There was no difference between T0 and T2 on HS. ACV increased 0.65cm3 between T0 and T1 on AS, after which it decreased by 0.36cm3 at T2 (0.30cm3 larger than the initial articular cavity at T0). ACV showed no post-surgery differences on HS. Midline DAU showed extrusion of 0.20mm for maxilla and 0.52mm for mandible, while in the lateral area, maxilla was extruded by 0.3mm on HS and was intruded 0.12mm on AS. For the mandible, both sides showed extrusion (0.4-0.6mm). In the distal to canine and molar areas, intrusion of 0.2mm and 0.9mm, respectively, was observed on AS; there was extrusion of 0.6mm distal to the canine on HS. At the mandibular level, AS distal to the canine showed extrusion of 1mm, while intrusion of 0.2mm was observed in the molars. For HS, only extrusion at the molar level (0.2mm) was observed. In conclusion, after proportional condylectomy, a neocondyle forms within 12 months to equal the healthy contralateral side. The articular cavity, which is reduced in the initial stage, increases in size after surgery and the volume gradually approaches that of the healthy side. Dentoalveolar changes occur at the anterior and posterior levels, causing intrusion and extrusion of the interdental crests. An early proportional condylectomy as the sole surgical treatment for patients with AUCH allows normalization of the maxillomandibular relationship.

Premenstrual syndrome (PMS) is a clinical entity of great importance in medical practice, due to its high prevalence and its symptomatic polymorphism. In 25 to 35% of women it is a worrisome problem, that requires specialized consultation and in 5 to 10% it becomes grave, due to the extension or seriousness of symptoms. According to our personal understanding, this is a toxic-inflammatory process with multisystemic involvement that erroneously leads women to consult diverse specialists such as neurologists, cardiologists, psychiatrists etc. Each of these professionals will prescribe symptomatic treatments with uncertain or negative results. PMS and its toxic-inflammatory components apparently acquires a progressive course and the lack of causal treatment may compromise women's fertility and lead to premature and mutilant surgical practices (hysterectomy).