138 results on '"J. M. Fitzpatrick"'
Search Results
2. An evaluation of selected (Q)SARs/expert systems for predicting skin sensitisation potential
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J. M. Fitzpatrick, D. W. Roberts, and G. Patlewicz
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Predictive testing to characterise substances for their skin sensitisation potential has historically been based on animal models such as the Local Lymph Node Assay (LLNA) and the Guinea Pig Maximisation Test (GPMT). In recent years, EU regulations, have provided a strong incentive to develop non-animal alternatives, such as expert systems software. Here we selected three different types of expert systems: VEGA (statistical), Derek Nexus (knowledge-based) and TIMES-SS (hybrid), and evaluated their performance using two large sets of animal data: one set of 1249 substances from eChemportal and a second set of 515 substances from NICEATM. A model was considered successful at predicting skin sensitisation potential if it had at least the same balanced accuracy as the LLNA and the GPMT had in predicting the other outcomes, which ranged from 79% to 86%. We found that the highest balanced accuracy of any of the expert systems evaluated was 65% when making global predictions. For substances within the domain of TIMES-SS, however, balanced accuracies for the two datasets were found to be 79% and 82%. In those cases where a chemical was within the TIMES-SS domain, the TIMES-SS skin sensitisation hazard prediction had the same confidence as the result from LLNA or GPMT.
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- 2018
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3. Matching Subjective Assessments of Sod Strength to Quantitative Measurements of Peak Shear Force with Predominately Kentucky Bluegrass Sod
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Holly Burdett, Karl Guillard, and Richard J. M. Fitzpatrick
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Matching (statistics) ,business.industry ,Shear force ,Structural engineering ,Horticulture ,business ,Mathematics - Abstract
Adequate turfgrass sod strength for harvesting and handling is typically determined by the producer’s past experience and subjective appraisal. This study was conducted to determine the relationship between producer subjective sod-strength assessments and quantitative shear-strength measurements with predominantly kentucky bluegrass (Poa pratensis L.) turf. Across three consecutive growing seasons, 93 samples were collected from sod fields in Rhode Island and assessed for sod strength by subjective and quantitative methods. Producer subjective ratings of sod strength were significantly (P < 0.0001) associated with quantitative measurements of peak force required to shear a sod strip. Minimally acceptable strength occurred most frequently when peak shear force was between 55 and 85 kg·m−1 width of sod; whereas preferred sod strength occurred most frequently when peak shear force was between 70 and 140 kg·m−1 width of sod. Once peak force exceeded 58 and 86 kg·m−1, there was a > 50% probability that sod strength would be judged at least adequate and at preferred strength, respectively, up to a peak force of 140 kg·m−1. The results suggest that quantitative measurements of shear strength can be related to producer subjective assessments, and provide unbiased benchmark values to guide management decisions for kentucky bluegrass sod production.
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- 2015
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4. Application of IATA – A case study in evaluating the global and local performance of a Bayesian network model for skin sensitization
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J. M. Fitzpatrick and G. Patlewicz
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The information characterizing key events in an Adverse Outcome Pathway (AOP) can be generated from in silico, in chemico, in vitro and in vivo approaches. Integration of this information and interpretation for decision making are known as integrated approaches to testing and assessment (IATA). One such IATA was published by Jaworska et al., which describes a Bayesian network model known as ITS-2. The current work evaluated the performance of ITS-2 using a stratified cross-validation approach. We also characterized the impact of replacing the most significant component of the network, output from the expert system TIMES-SS, with structural alert information from the OECD Toolbox and Toxtree. Lack of structural alerts or TIMES-SS predictions yielded a sensitization potential prediction of 79%. If the TIMES-SS prediction was replaced by a structural alert indicator, the network predictivity increased up to 87%. The original network’s predictivity was 89%. The local applicability domain of the original ITS-2 network was also evaluated using reaction mechanistic domains to understand what types of chemicals ITS-2 was able to make the best predictions for. We found that the original network was successful at predicting which chemicals would be sensitizers, but not at predicting their potency.
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- 2017
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5. A study on the theoretical and practical accuracy of conoscopic holography-based surface measurements: toward image registration in minimally invasive surgery
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J. M. Fitzpatrick, Stanley Duke Herrell, Amber L. Simpson, Jessica Burgner, Michael I. Miga, Ray A. Lathrop, and Robert J. Webster
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Surface (mathematics) ,business.industry ,Computer science ,Biophysics ,Holography ,Image registration ,Robotics ,Imaging phantom ,Computer Science Applications ,law.invention ,Image-guided surgery ,law ,Invasive surgery ,Surgery ,Point (geometry) ,Computer vision ,Artificial intelligence ,business - Abstract
Background Registered medical images can assist with surgical navigation and enable image-guided therapy delivery. In soft tissues, surface-based registration is often used and can be facilitated by laser surface scanning. Tracked conoscopic holography (which provides distance measurements) has been recently proposed as a minimally invasive way to obtain surface scans. Moving this technique from concept to clinical use requires a rigorous accuracy evaluation, which is the purpose of our paper. Methods We adapt recent non-homogeneous and anisotropic point-based registration results to provide a theoretical framework for predicting the accuracy of tracked distance measurement systems. Experiments are conducted a complex objects of defined geometry, an anthropomorphic kidney phantom and a human cadaver kidney. Results Experiments agree with model predictions, producing point RMS errors consistently
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- 2012
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6. The West Pacific diversity hotspot as a source or sink for new species? Population genetic insights from the Indo-Pacific parrotfish Scarus rubroviolaceus
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David B. Carlon, Catherine Lippé, J. M. Fitzpatrick, and D. R. Robertson
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education.field_of_study ,biology ,Ecology ,Population ,Peripatric speciation ,biology.organism_classification ,Population density ,Gene flow ,Genetic Speciation ,Genetic variation ,Genetics ,Parrotfish ,education ,Ecology, Evolution, Behavior and Systematics ,Indo-Pacific - Abstract
We used a population genetic approach to quantify major population subdivisions and patterns of migration within a broadly distributed Indo-Pacific parrotfish. We genotyped 15 microsatellite loci in Scarus rubroviolaceus collected from 20 localities between Africa and the Americas. A STRUCTURE model indicates the presence of four major populations: Eastern Pacific, Hawaii, Central-West Pacific and a less well-differentiated Indian Ocean. We used the isolation and migration model to estimate splitting times, population sizes and migration patterns between sister population pairs. To eliminate loci under selection, we used BayeScan to select loci for three isolation and migration models: Eastern Pacific and Central-West Pacific, Hawaii and the Central-West Pacific, and Indian Ocean and the Central-West Pacific. To test the assumption of a stepwise mutation model (SMM), we used likelihood to test the SMM against a two-phase model that allowed mutational complexity. A posteriori, minor departures from SMM were estimated to affect ≤2% of the alleles in the data. The data were informative about the contemporary and ancestral population sizes, migration rates and the splitting time in the eastern Pacific/Central-West Pacific comparison. The model revealed a splitting time ∼17,000 BP, a larger contemporary N(e) in the Central-West Pacific than in the eastern Pacific and a strong bias of east to west migration. These characteristics support the Center of Accumulation model of peripatric diversification in low-diversity peripheral sites and perhaps migration from those sites to the western Pacific diversity hotspot.
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- 2010
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7. Differential mechanisms of bicalutamide-induced apoptosis in prostate cell lines
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M S, Floyd, M St John, Floyd, S J, Teahan, J M, Fitzpatrick, and R W G, Watson
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Male ,Cancer Research ,Bicalutamide ,medicine.drug_class ,Urology ,Antineoplastic Agents ,Apoptosis ,Pharmacology ,Antiandrogen ,Flow cytometry ,Tosyl Compounds ,Prostate cancer ,Cell Line, Tumor ,Nitriles ,medicine ,Humans ,Anilides ,Caspase ,medicine.diagnostic_test ,biology ,business.industry ,Prostate ,Prostatic Neoplasms ,Calpain ,Flow Cytometry ,medicine.disease ,Oncology ,Cell culture ,biology.protein ,business ,medicine.drug - Abstract
Bicalutamide is a non-steroidal antiandrogen used in the treatment of prostate cancer. Although widely accepted as an androgen receptor antagonist, the mechanism by which it induces apoptosis remains unclear. Defining exact pathways by which bicalutamide induces its apoptotic effects would help to advance its clinical applications. We aimed to (a) examine the apoptotic effects of bicalutamide at 24 h and (b) comment on the role of the caspases and calpains in mediating bicalutamide-induced apoptosis in androgen-dependent and androgen-independent cells. PWR-1E, PC-3 and DU-145 cells were treated with bicalutamide and assessed for apoptosis by flow cytometry at 24 h. DU-145 cells were used to compare differences between two different metastatic receptor-negative cells and to verify apoptotic induction at 48 h. To delineate a specific pathway of action for bicalutamide, PC-3 and PWR-1E cells were pretreated with specific inhibitors of caspase-dependent (zVAD-FMK) and caspase-independent pathways (calpain 2 inhibitor). Bicalutamide induced apoptosis in androgen-dependent PWR-1E cells via a caspase-dependent and calpain-independent mechanism. In androgen-independent PC-3 cells, bicalutamide also induced apoptosis by mechanisms that were partially inhibited by pan-caspase inhibition but were partially calpain dependent. Understanding into how bicalutamide exerts its effects in androgen-independent cells will yield further insights into the treatment of hormone-refractory disease.
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- 2008
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8. Kentucky Bluegrass Response to Potassium and Nitrogen Fertilization
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Karl Guillard and Richard J. M. Fitzpatrick
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Clipping (audio) ,Poa pratensis ,Potassium ,chemistry.chemical_element ,Biology ,biology.organism_classification ,Nitrogen ,Nitrogen fertilizer ,Human fertilization ,Agronomy ,chemistry ,Loam ,Poaceae ,Agronomy and Crop Science - Abstract
The response of Kentucky bluegrass (Poa pratensis L.) to potassium (K) fertilization has been inconsistent. The objective of this research was to determine the effects of K fertilization across varying nitrogen (N) rates and clipping management on Kentucky bluegrass clipping yields, quality, tissue K concentrations, apparent N recovery, and N use efficiency. A 2 × 4 x 4 factorial was arranged in a split-plot design and repeated across two years. Main plots were clipping treatments (returned vs. removed) and subplots were N rates (0, 98, 196, and 294 kg ha -1 yr -1 ) in combination with K rates (0, 81, 162, and 243 kg ha -1 yr -1 ). There was no positive effect of K on clipping yields and quality even though soil extractable K levels tested low. Higher K rates, however, increased N recovery and use efficiency for all but the highest N rate. Tissue K response to K fertilization was nonlinear. Yield and quality responses were not correlated to tissue K concentration. Nonexchangeable K levels were high in the native soil, and may have provided an additional source of K for bluegrass. The results suggest that extractable K values alone may not adequately predict available K to Kentucky bluegrass in this sandy loam soil.
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- 2004
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9. Irish society of gastroenterology
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B. M. Ryan, S. McKiernan, P. W. N. Keeling, P. J. Byrne, R. Quill, K. McCallion, R. M. S. Mitchell, R. G. P. Watson, J. S. A. Collins, K. R. Gardiner, D. C. Winter, G. C. O’Sullivan, C. T. Taylor, N. F. Fanning, H. P. Redmond, D. P. O’Donoghue, A. W. Baird, B. J. Harvey, A. E. Brannigan, P. R. O’Connell, M. C. Regan, J. M. Fitzpatrick, R. W. G. Watson, H. Lemass, E. Ryan, P. MacMathuna, J. Crowe, J. C. O’Keane, J. Goh, A. Baird, L. Maher, C. Godson, H. R. Brady, N. A. Petasis, V. V. Fokin, M. K. Barry, D. C. Grant, K. Sheahan, J. M. P. Hyland, K. M. Sheehan, D. J. Fitzgerald, F. E. Murray, A. Heaney, K. B. Bamford, R. J. McFarland, T. C. K. Tham, D. McNamara, S. Franelli, H. Whelan, H. Hamilton, S. Beattie, C. O’Morain, E. G. Brennan, N. O’Hare, R. McDermott, N. I. McDougall, C. M. Gieeson, S. E. H. Russell, J. M. Sloan, D. Morrisey, L. Murphy, B. Kiely, G. Fitzgerald, C. Daly, G. O’Sullivan, F. Shanahan, J. K. Collins, P. Marteau, S. D. Johnston, C. Coates, C. Feighery, J. O’Keeffe, A. Whelan, S. Lynch, D. G. Weir, M. Abuzakouk, L. Barnes, N. O’Gorman, M. McKenna, R. Freaney, M. Young, S. Gaines, D. Brady, D. Drudy, C. O’Farrelly, A. Gilleece, L. Fenelon, J. McPartlin, A. M. Hopkins, A. Myers, P. Moynagh, J. M. Kirby, M. J. Allen, B. Best, H. Calvert, S. Kirk, S. T. D. McKelvey, R. J. Moorehead, J. C. Varghese, S. Sookhai, T. Walsh, H. Osborne, P. Broe, M. J. Lee, D. Moriarty, R. Coffey, E. Murphy, A. A. Shah, E. Murray, B. Thjodleifsson, I. Bjarnason, S. Montague, C. Forkin, G. C. O’Toole, C. M. Gallagher, P. Connell, O. Traynor, T. C. Ling, B. Johnston, M. F. Byrne, M. A. Farrell, C. A. Goulding, S. S. Albloushi, P. O’Connell, L. E. Graham, T. J. Robinson, T. Jabeen, B. Cannon, D. Jenkins, M. J. Whelton, S. Bohra, C. Keohane, M. Duggan, R. K. Siddheshwar, R. G. Wilson, P. J. Hainsworth, F. C. Campbell, S. B. Kelly, B. M. Egan, C. Simutowe, D. A. McNamara, N. Collins, T. N. Walsh, A. Mukherjee, M. Scott, C. Pohl, E. Duggan, M. Wasi, A. Sarkar, L. O. Donnell, P. W. Eustace, J. G. Johnston, R. Waldron, S. Barrett, G. Callagy, J. C. O. Keane, B. Coughlan, J. Sheehan, A. Hickey, A. Carr, M. R. Kell, M. Lynch, D. Ryan, P. Rajpal, W. O. Kirwan, C. J. Larkin, J. E. S. Ardill, K. D. Buchanan, P. L. Lim, M. Gibbons, E. J. Crawford, B. T. Johnston, C. Rodgers, S. Johnston, B. M. Crone, A. H. G. Love, L. Feighery, J. Jackson, M. M. I. Yassin, D. W. Harkin, A. A. B. Barros D’sa, T. G. Parks, M. P. Curry, J. E. Hegarty, L. Golden-Mason, E. Hannigan, and N. Parfrey
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medicine.medical_specialty ,Pediatrics ,Irish ,business.industry ,Family medicine ,medicine ,language ,General Medicine ,business ,language.human_language - Published
- 1998
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10. Sylvester o’halloran surgical scientific meeting
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N. Relihan, G. McGreal, M. Murray, E. W. McDermott, N. J. O’Higgins, M. J. Duffy, D. A. McNamara, J. Harmey, J. H. Wang, D. Donovan, T. N. Walsh, D. J. Bouchier-Hayes, E. Kay, J. D. Kelly, H. P. Weir, P. F. Keane, S. R. Johnston, K. E. Williamson, P. W. Hamilton, D. McManus, M. Morrin, P. V. Delaney, D. C. Winter, B. J. Harvey, J. P. Geibel, G. C. O’Sullivan, C. P. Delaney, R. Coffey, T. F. Gorey, J. M. Fitzpatrick, N. F. Fanning, W. Kirwan, T. Cotter, D. Bouchier-Hayes, H. P. Redmond, G. Pidgeon, F. Fennessy, C. Kelly, R. Flavin, A. M. Rasheed, A. Leahy, E. E. Lang, M. T. P. Caldwell, W. A. Tanner, P. D. Kiely, M. O’Reilly, S. Tierney, M. Barry, J. Drumm, P. A. Grace, C. M. Gallagher, D. C. Grant, P. Connell, M. K. Barry, O. Traynor, J. M. P. Hyland, M. J. O’Sullivan, D. Evoy, W. O. Kirwan, B. Cannon, L. Kenny-Walshe, M. J. Whelton, H. O’Grady, S. O’Neill, J. M. Hyland, S. H. Teh, S. O’Ceallaigh, M. K. O’Donohoe, F. B. Keane, G. C. O’Toole, J. Calleary, L. Basso, S. B. Amjad, Z. Khan, L. McMullin, W. P. Joyce, P. J. Balfe, M. T. Caldwell, S. Teahan, K. Al-Brekeit, A. Rasheed, A. Cullen, C. O’Keane, J. MacFarlane, M. Walsh, T. McGloughlin, P. Grace, D. Colgan, P. Madhavan, S. Sultan, M. P. Colgan, D. Moore, G. Shanik, N. McEniff, M. Molloy, E. Eguare, C. Fiuza, P. Burke, R. Maher, M. Creamer, C. J. Cronin, H. H. Sigurdsso, W. Kim, G. Linklater, K. S. Cross, W. G. Simpson, J. A. M. Shaw, D. W. M. Pearson, P. Fitzgerald, P. Quinn, C. M. Brady, S. M. A. Shah, M. Ehtisham, M. S. Khan, H. D. Flood, M. Loubani, K. Sweeney, B. Lenehan, V. Lynch, A. Joy, D. Reidy, K. Mahalingam, W. Cashman, E. D. Mulligan, T. Purcell, B. Dunne, M. Griffin, N. Noonan, D. Hollywood, N. Keeling, J. V. Reynolds, T. P. J. Hennessy, D. O’Halloran, P. Neary, D. Hamilton, N. Haider, N. Aherne, R. G. K. Watson, D. Walsh, M. Murphy, M. Joyce, S. Johnston, O. Clinton, H. F. Given, A. Brannigan, M. O’Donohoe, J. Donohoe, T. Corrigan, M. Bresnihan, T. M. Feeley, M. P. McMonagle, D. Quinlan, D. Kelly, P. K. Hegarty, B. Tan, C. Cronin, M. P. Brady, M. Zeeshan, D. J. McAvinchey, C. Mooney, D. Coyle, G. Khayyat, E. Masterson, T. Thambi-Pillai, K. Farah, M. B. Codd, G. G. Tsiotos, C. D. Johnson, M. G. Sarr, M. R. Kell, M. Lynch, D. Ryan, A. O’Donovan, M. Cassidy, M. Doyle, G. Fulton, P. R. O’Connell, R. Kingston, M. Dillon, E. McDermott, N. O’Higgins, R. G. O’Sullivan, and J. A. O’Donnell
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business.industry ,Foundation (engineering) ,Medicine ,Library science ,General Medicine ,business - Published
- 1998
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11. Royal academy of medicine in Ireland section of bioengineering
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P. J. Prendergast, I. Callanan, C. Simms, C. G. Lyons, C. L. Brady, M. S. Feeney, D. Lennon, L. J. Curley, B. A. O. McCormack, T. M. O’Brien, V. Waide, A. J. Carr, P. Ferris, H. J. Rice, A. W. Blayney, S. Tierney, D. Buckley, F. Bonnadio, J. M. Fitzpatrick, T. F. Gorey, P. G. Donnelly, G. T. H. Wright, K. E. Tanner, W. Bonfield, N. V. Girish Kumar, D. Rawlings, J. L. Sher, R. Cullinan, M. T. Young, S. C. O’Rourke, R. Howard-Hildige, G. Insley, D. P. Dowling, K. Donnelly, P. V. Kola, T. C. Kelly, K. Brummitt, L. Lloyd, R. Eloy, M. Therin, N. Weill, E. P. Battles, R. G. Hill, A. Devitt, J. Rice, D. McCormack, P. Felle, F. McManus, K. J. Bryan, M. Buggy, F. Kirrane, J. F. Malone, E. Coyle, B. Stewart, S. Hatfield, M. Farrell, F. Duignan, R. Reilly, D. Bray, P. Kenny, S. K. O’Rourke, A. K. Ryan, J. F. Orr, C. Mitchell, A. C. Murphy, P. O’Neill, P. Chawke, C. Birkinshaw, J. J. Leahy, D. Taylor, J. P. O’Reilly, J. M. Manning, B. F. Masterson, J. M. Duffy, R. J. Winder, G. J. Gilmore, D. Gallagher, H. K. Graham, J. Rodda, R. Boyd, D. Cantillon, F. Fushimi, C. D. Nugent, J. A. C. Webb, N. D. Black, A. Boyd, B. J. Meenan, M. Akay, N. Leyland, S. Maher, N. Smith, D. C. Sun, C. Stark, J. H. Dumbleton, D. B. Keenan, F. J. Owens, D. Pichon, N. Nawana, A. Kavanagh, T. McGloughlin, W. D. van Driel, R. Huiskes, J. O’Connor, A. Leardini, T. W. Lu, F. Catani, T. C. Lee, T. L. Arthur, L, J. Gibson, E. R. Myers, W. C. Hayes, R. Gill, W. L. Chen, and P. Kelly
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medicine.medical_specialty ,business.industry ,Ophthalmology ,Section (typography) ,Library science ,Medicine ,General Medicine ,business - Published
- 1998
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12. Sylvester o’halloran surgical scientific meeting
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G. J. Fulton, M. G. Davies, P. O’Hagen, A. Rasheed, C. Kelly, E. Kay, S. Fitzgerald, D. Bouchier-Hayes, A. Leahy, F. Fennessy, P. Fitzgerald, K. Khosraviani, H. P. Weir, K. Williamson, R. Wilson, R. J. Moorehead, B. J. Rowlands, D. Morrissey, J. O’Connell, D. Lynch, C. O’Sullivan, F. Shanahan, J. K. Collins, J. L. Kelly, C. C. Soberg, A. Lyons, J. A. Mannick, J. A. Lederer, C. Chen, D. J. Bouchier-Hayes, H. Fitzsimons, D. M. O’Hanlon, C. Curran, M. Canney, S. Morris, O. Clinton, H. F. Given, E. Coveney, H. K. Lyerly, F. L. Murphy, C. J. Kelly, D. H. Osborne, P. Kelly, D. S. O’Riordan, P. G. Horgan, F. B. V. Keane, W. A. Tanner, P. Kilmartin, C. P. Delaney, S. M. Johnston, J. M. Fitzpatrick, T. F. Gorey, J. Mehigan, M. G. O/rsRiordan, N. Shines, A. Hill, C. O. McDonnell, F. Murphy, S. M. Javadpour, Y. Alhadi, R. Waldron, R. G. Watson, A. Tarrant, T. K. Neelamekam, J. Mathias, J. Geoghegan, T. Boyle, O. Traynor, S. Hayes, B. O’Donovan, N. Ajmal, J. McCann, N. T. Corrigan, M. G. O’Riordan, P. Ross, M. O’Donohoe, M. Bresnihan, T. M. Feeley, C. Fiuza-Castineira, D. Coleman, H. Fisher, A. Butt, E. Ghumman, P. Grace, P. Burke, S. A. Martin, M. K. Fox-Talbot, P. A. Lipsett, K. D. Lillemoe, H. A. Pitt, D. A. O’Keeffe, A. D. K. Hill, K. Sheahan, F. Ryan, D. Barton, R. Fitzgerald, E. W. McDermott, N. J. O’Higgins, E. Kavanagh, P. Kiely, D. O’Driscoll, M. Ramesh, W. O. Kirwan, D. C. Winter, K. Nally, J. O’Callaghan, J. B. Matthews, B. J. Harvey, G. C. O’Sullivan, L. S. Young, M. C. Regan, P. Sweeney, D. M. Bouchier-Hayes, R. Dardis, P. Broe, M. G. O’Brien, P. Neary, P. Ridgeway, C. Condron, J. H. Wang, H. P. Redmond, D. R. M. Redfern, R. K. S. Strachan, J. M. Hollingdale, P. A. Grace, A. Acheson, A. Graham, C. Weir, B. Lee, C. O’Donnell, D. Buckley, J. A. O’Donnell, E. Purcell, M. O’Donoghue, S. Sultan, M. Colgan, M. Molloy, D. Moore, G. Shanik, P. T. McCollum, Z. Raza, S. Naidu, P. A. Stonebridge, M. P. Colgan, D. J. Moore, D. G. Shanik, J. Dowdall, C. Williams, S. G. Shering, G. Duffy, R. Greengrass, D. Iglehart, G. Little, H. Kim Lyerly, M. Fynes, A. Cahill, C. O’Herlihy, P. R. O’Connell, I. Ahmad, M. Etisham, J. Drumm, H. Flood, K. Mulhall, K. Murray, S. O’Rian, N. Garvey, J. Johnston, G. T. McGreal, M. P. Brady, M. M. Duffy, M. Regan, M. G. Harrington, M. Javadpour, C. McDonnell, E. Eguare, M. C. Barry, G. C. O’Toole, N. O’Higgins, E. McDermott, C. M. Brady, S. A. Sultan, M. K. O’Donoghue, M. P. Molloy, G. D. Shanik, R. J. Holdsworth, M. Fehily, C. Doran, F. Keane, J. F. Rothwell, M. J. Staunton, L. O’Mahony, E. F. Gaffney, K. Mealy, T. P. J. Hennessy, and J. Geibel
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business.industry ,Art history ,Medicine ,General Medicine ,business - Published
- 1998
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13. Irish society of gastroenterology
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G. Clarke, E. Ryan, J. C. O’Keane, J. Crowe, P. McMathuna, D. Moriarty, R. Ettarh, K. Sheahan, J. Hyland, D. P. O’Donoghue, A. W. Baird, G. Gormley, J. C. O. Keane, P. MacMathuna, J. H. Wang, Q. D. Wu, H. P. Redmond, C. Condron, D. Bouchier-Hayes, K. Nally, F. Newton, J. O’Connell, G. C. O’Sullivan, J. Morgan, J. K. Collins, F. Shanahan, C. Goode, D. C. Winter, C. T. Taylor, M. M. Skelly, B. J. Harvey, J. C. Varghese, M. A. Farrell, F. P. McGrath, F. E. Murray, H. Osborne, M. J. Lee, A. Sullivan, A. E. Ryan, A. N. Donovan, P. A. McCormick, B. Kenny, S. Somers, A. Bohan, R. G. Gibney, M. Marcaccio, D. E. Malone, M. Doyle, C. P. Delaney, T. F. Gorey, G. P. McEntee, A. Clarke, R. Stuart, J. Kelly, M. D. Kiely, M. O’Sullivan, E. Lovett, N. Mahmud, D. Kelleher, C. A. O’Morain, C. J. Larkin, R. G. P. Watson, J. M. Sloan, J. E. S. Ardill, C. F. Johnston, K. D. Buchanan, A. Heaney, J. S. A. Collins, G. R. P. Watson, R. M. Kalin, T. C. K. Tham, R. J. McFarland, K. B. Bamford, T. Ó Cróinín, M. Clyne, B. Drumm, M. Rowland, D. Kumar, P. O’Connor, L. E. Daly, D. L. O’Toole, A. Long, A. M. Murphy, L. O’Neill, D. G. Weir, A. M. Hopkins, P. Moynagh, C. Brennan, J. Harmey, P. P. Stapleton, A. M. Rasheed, G. Chen, C. Kelly, D. J. Bouchier-Hayes, A. Leahy, M. Gallagher, A. Grace, Y. Xin, M. Leader, E. Kay, A. Whelan, U. Pattison, R. Willoughby, E. Wallace, D. Weir, C. Feighery, M. W. Bennett, C. Brady, D. Roche, A. Molloy, J. McPartlin, J. M. Scott, A. G. Acheson, J. Lee, K. Khosraviani, S. T. Irwin, J. McDaid, J. R. Docherty, A. O’Grady, M. Mabruk, C. Johnston, W. Curry, J. Ardill, R. Cunningham, N. I. McDougall, P. V. Coyle, M. E. Callender, A. M. Ouinn, R. Warner, F. M. Stevens, P. I. S. Chakravarthi, M. Kearns, M. Bourke, A. Hassan, J. McWeeney, C. F. McCarthy, M. Casey, J. O’Donoghue, A. M. Eustace-Ryan, P. O’Regan, L. Feighery, J. Jackson, N. Cronin, K. Quane, E. D. Mulligan, T. Purcell, B. Dunne, M. Griffin, N. Noonan, D. Hollywood, N. Keeling, J. V. Reynolds, T. P. J. Hennessy, M. O’Sulhvan, I. Harman, N. P. Breslin, N. Clayton, S. Hogan, B. Donovan, D. Hayes, M. Kiely, C. A. Goulding, S. S. Albloushi, J. O’Connor, M. G. Courtney, D. Royston, A. G. Shattock, A. Stack, M. Carmody, S. Barrett, A. Hennigan, L. Young, C. J. Shields, C. O’Keane, J. M. Fitzpatrick, M. M. Doyle, R. B. Stephens, P. A. Daly, G. M. Briggs, D. McCrory, S. O’Neill, H. O’Grady, D. C. Grant, K. Barry, O. Traynor, J. M. P. Hyland, G. C. O’Toole, M. K. Barry, S. D. Johnston, C. M. Ritchie, T. J. Robinson, J. M. Kirby, E. M. Mackle, N. Haider, N. Aherne, F. McNichol, D. Hamilton, P. Neary, S. Hegarty, J. O. Connor, R. G. K. Watson, D. Drudy, A. Alwan, L. Fenelon, C. O’Farrelly, B. Byrne, L. Madrigal, J. Carton, C. Collins, D. O’Donoghue, N. Gannon, A. Hickey, C. A. O’Boyle, R. Byrne, S. Albloushi, and F. Murray
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medicine.medical_specialty ,Irish ,business.industry ,Ophthalmology ,language ,Library science ,Medicine ,General Medicine ,business ,language.human_language - Published
- 1998
- Full Text
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14. Irish Society of Gastroenterology
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M. Woods, L. J. D. O’Donnell, B. Battistini, T. Warner, J. Vane, M. G. Fartming, J. Yaqoob, J. J. Wu, L. A. Norris, M. I. Khan, P. W. N. Keeling, D. Maguire, G. O’Sullivan, B. Harvey, B. Curran, Y. Xin∘, E. W. Kay, M. Leader, K. Henry, O. Crosbie, S. Norris, P. Costello, C. O’Farrelly, J. Hegarty, B. Kennedy, M. Duggan, R. Plant, E. K. Kenny-Walsh, P. Cotter, M. J. Whelton, M. Maloney, N. Noonan, M. Buckley, H. Hamilton, S. Beattie, C. O’Morain, B. McNamara, J. Cuffe, R. A. Barry, D. A. Collins, G. C. O’Sullivan, J. K. Collins, F. Shanahan, M. M. Skelly, H. E. Mulcahy, A. Troy, T. Connell, C. Duggan, M. J. Duffyt, K. Sheahan, D. P. O’Donoghue, H. X. Xia, D. Hyde, M. G. O’Brien, E. F. Fitzgerald, G. Lee, A. J. Hussey, T. J. Boyle, B. Garrihy, O. P. Clinton, O. J. McAnena, G. O’Sulllvan, H. Corby, V. Donnelly, C. O’Herlihy, P. R. O’Connell, T. Deignan, J. Kelly, N. P. Breslin, C. MacDonnell, J. O’Keeffe, K. Mills, U. Srinivasan, R. Willoughby, C. Feighery, B. Twohig, K. Gaynor, P. F. O’Regan, S. Duggan, H. P. Redmond, J. McCarthy, D. Bouchier-Hayes, Q. Y. Ma, K. E. Williamson, B. J. Rowlands, A. Tobin, R. Pilkington, M. O’Donnell, E. O’Shea, A. Conroy, G. Kaminski, A. Walsh, I. J. Temperley, D. Kelleher, D. G. Weir, M. K. Barry, E. D. Mulligan, M. A. Stokes, M. G. O’Riordain, T. F. Gorey, K. F. McGeeney, J. M. Fitzpatrick, R. W. G. Watson, J. H. Wang, F. Campbell, D. Bennett, E. Kavanagh, P. O. Gorman, P. O’Regan, M. M. I. Yassin, M. McCaigue, T. G. Parks, A. A. B. Barros D’Sa, M. Lawlor, S. McElwaine, M. A. Heneghan, M. Kerins, J. Goulding, E. L. Egan, F. M. Stevens, C. F. McCarthy, M. Quirke, A. M. Eustace-Ryan, S. Qureshi, E. Aziz, A. Maree, S. Collins, T. Browne, S. Ahmed, B. O. Sullibhan, P. Smith, F. Walker, F. O’Connor, E. Sweeney, R. J. Farrell, M. Morrint, M. Goggins, and J. G. McNulty
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medicine.medical_specialty ,Irish ,business.industry ,Ophthalmology ,language ,medicine ,Library science ,General Medicine ,business ,language.human_language - Published
- 1995
- Full Text
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15. Sir Peter Freyer Memorial Lecture and Surgical Symposium 15th and 16th September, 1995
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J. Calleary, C. Tansey, J. McCormack, S. Kapur, J. Doyle, J. Flynn, A. J. Curran, D. Smyth, B. Kane, M. Toner, C. V. I. Timon, K. J. Cronin, J. O’Donoghue, F. X. Darmanin, J. McCann, F. Campbell, H. P. Redmond, C. Condron, D. Bouchier-Hayes, K. Aizaz, S. W. MacGowan, A. F. O’Donnell, D. A. Luke, E. McGovern, M. Morrin, F. Khan, P. V. Delaney, S. M. Lavelle, B. Kanagaratnam, V. Cuervas-Mons, A. Gauthier, C. Gips, R. Marques dos Santos, G. P. Molino, A. Theodossi, D. D. Tsiftsis, C. J. O. Boyle, T. J. Boyle, M. J. Kerin, D. M. Courtney, D. S. Quill, H. F. Given, D. F. O’Brien, E. J. Kelly, J. Kelly, D. Richardson, N. F. Fanning, R. Brennan, P. G. Horgan, F. B. V. Keane, S. Reid, C. Walsh, R. Patock, J. Hall, D. Evoy, M. Magd-Eldin, D. Curran, P. Keeling, N. Ade-Ajayi, L. Spitz, E. Kiely, D. Drake, N. Klein, D. M. O’Hanlon, D. Karat, K. Callanan, W. Crisp, S. M. Griffin, P. M. Murchan, B. Mancey-Jones, P. Sedman, C. J. Mitchell, J. Macfie, D. Scott, S. Raimes, C. J. O’Boyle, D. Maher, P. C. Willsher, J. F. R. Robertson, M. Hilaly, R. W. Blarney, S. G. Shering, S. Mitrovic, A. Rahim, E. W. McDermott, N. J. O’Higgins, C. A. Murphy, D. Morgan, C. W. Elston, I. O. Ellis, M. P. O’Sullivan, M. G. O’Riordain, J. P. Stack, M. K. Barry, J. T. Ennis, J. M. Fitzpatrick, T. F. Gorey, J. Kollis, H. Mullet, D. F. Smith, A. Zbar, M. J. Murray, E. W. M. McDermott, P. P. A. Smyth, N. Kapucouglu, S. Holmes, P. Holland, P. T. McCollum, A. da Silva, L. de Cossart, D. Hamilton, C. J. Kelly, K. Stokes, P. Broe, J. Crinnion, P. A. Grace, N. Morton, N. Ross, S. Naidu, P. Gervaz, R. J. Holdsworth, P. A. Stonebridge, A. O’Donnell, K. Carson, D. Phelan, S. McBrinn, D. McCarthy, H. Javadpour, J. McCarthy, M. Neligan, M. T. P. Caldwell, J. P. McGrath, P. J. Byrne, T. N. Walsh, P. Lawlor, C. Timon, R. C. Stuart, K. Murray, A. Carney, J. G. Johnston, B. Egan, P. R. O’Connell, J. Donoghue, A. Pollock, D. Hyde, D. Hourihan, W. A. Tanner, J. Donohue, N. Fanning, P. Horgan, A. Mahmood, K. Dave, J. Stewart, A. Cole, R. Hartley, T. G. Brennan, J. M. O’Donoghue, S. T. O’Sullivan, E. Beausang, J. Panchal, M. O’Shaughnessy, P. O’Grady, R. W. G. Watson, D. Johnstone, J. O’Donnell, E. McCarthy, N. Flynn, T. O’Dwyer, C. Curran, S. Duggan, S. Tierney, Z. Qian, P. A. Lipsett, H. A. Pitt, K. D. Lillemoe, J. Kollias, D. A. L. Morgan, I. S. Young, M. C. Regan, J. G. Geraghty, C. B. O. Suilleabhain, M. L. Rodrick, A. F. Horgan, J. A. Mannick, J. A. Lederer, T. P. J. Hennessy, M. Canney, K. Feeley, C. E. Connolly, H. Abdih, N. Finnegan, M. Da Costa, M. Shafii, A. J. Martin, D. Mulcahy, M. Dolan, M. Stephens, F. McManus, M. Walsh, D. P. O’Brien, J. P. Phillips, T. A. Carroll, D. O’Brien, D. Rawluk, T. Sullivan, K. Herbert, M. Kerins, M. O’Donnell, D. Lawlor, M. McHugh, G. Edwards, J. Rice, J. P. McCabe, J. Sparkes, S. Hayes, M. Corcoran, H. Bredin, D. O’Keeffe, J. Candon, E. D. Mulligan, T. H. Lynch, D. Mulvin, L. Vingers, J. M. Smith, H. Corby, K. Barry, I. Eardley, J. Frick, B. Goldwasser, P. Wiklund, E. Rogers, R. Weaver, P. T. Scardino, R. Kumar, P. Puri, A. B. Adeyoju, T. Lynch, J. Corr, T. E. D. McDermott, R. Grainger, J. Thornhill, M. Butler, D. Keegan, N. Hegarty, P. McCarthy, A. H. Mirza, M. O’Sullivan, P. Neary, T. P. F. O’Connor, D. McCormack, K. Cunningham, N. Cassidy, K. Mulhall, M. Murphy, A. Puri, B. Dhaif, P. D. Carey, R. J. Delicata, F. Abbasakoor, R. B. Stephens, A. J. Hussey, B. Garrihy, D. J. Nolan, O. J. McAnena, R. Fitzgerald, D. Watson, B. J. Coventry, P. Malycha, S. C. Ward, S. P. Y. Kwok, W. Y. Lau, J. W. Bergman, G. E. B. Hacking, C. Metreweli, A. K. C. Li, P. Madhavan, J. Donohoe, M. O’Donohue, D. A. McNamara, and M. K. O’Donohoe
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business.industry ,Medicine ,General Medicine ,business ,Classics - Published
- 1995
- Full Text
- View/download PDF
16. Waterford surgical october club meeting and surgical section, royal academy of medicine in Ireland
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D. H. L. Chin, M. L. Rodrick, David Bouchier-Hayes, Frank B. V. Keane, H. F. Given, A. E. Brannigan, R. W. G. Watson, Colm O'Herlihy, J. M. Fitzpatrick, A. McNamara, K. Stokes, S. T. O’Sullivan, R. Page, W. Beesley, S. Sheehan, J. Geraghty, C. J. Kelly, G. O’Leary, P. Curley, F. B. W. Keane, Dermot J. Moore, A. F. Horgan, J. A. Mannick, H. Osborne, S. G. Crowe, T. K. Neelamekam, J. A. Shami, L. Kelly, D. G. Shanik, Henry Paul Redmond, M G Flynn, J. P. McDermott, M. L. Da Costa, C. J. O’Boyle, Mary-Paula Colgan, M. C. Regan, S. E. A. Attwood, S. Smith, Michael J. Kerin, M. A. Stokes, H. Corby, Thomas F. Gorey, M. Wall, P. R. O'Connell, Oscar Traynor, P. Gillen, J. H. Wang, K. Mealy, R. O’Dwyer, A. Tanner, M. C. Grouden, V. S. Donnelly, G. P. McEntee, K. Yacoub, M. K. Barry, W. A. Tanner, D. M. O’Hanlon, G. McEntee, Terry Boyle, and D. J. Bouchier-Hayes
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medicine.medical_specialty ,business.industry ,General surgery ,Ophthalmology ,Medicine ,General Medicine ,Club ,business ,Surgical section - Published
- 1994
- Full Text
- View/download PDF
17. Sylvester O’halloran surgical scientific meeting
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F. Malone, Michael J. Duffy, W. A. Tanner, L. Young, Joseph Deasy, T. P. O≿dwyer, F. Flanagan, J. Drumm, R. G. Barclay, P. V. Delaney, J. McCarthy, Terry Boyle, J. A. Thornhill, T. M. Feeley, R. O≿donnel, S. Duggan, P. Sweeney, J. Callahan, G. M. Lennon, D. J. Hehir, J. M. O≿donoghue, F. Graham, H. S. Rogers, M. D. McCaigue, B. Strunz, O. Traynor, F. Jakoubek, H. Naama, P. R. O≿connell, S. J. Sheehan, H. Grimes, T. E. D. Mcdermott, I. Shuaib, M. Barry, Ivan Keogh, C. Campbell, Enda W. McDermott, P. Burke, R. O≿sullivan, Henry Paul Redmond, G. O. Sullivan, H. Mcloughlin, P. Horgan, P. A. Grace, T. Gorey, Seamus Morris, P. Broe, John Russell, M. A. Stokes, J. G. Johnston, Mary-Paula Colgan, M. I. Halliday, Q. Y. Ma, F. Loughnane, G. D. Magee, D. Kelly, J. Shou, Frank B. V. Keane, Jill J. F. Belch, F. Khan, D. O≿hanlon, T. Nyhan, A. Hennessy, P. W. Eustace, S. K. Al-Ghazal, H. F. Given, David Mulvin, P. J. Meagher, B. J. Rowlands, C. B. O. Suilleabhain, S. Baldota, J. Ennis, C. Waters, I. M. Halliday, M. D. Morasch, P. Madhavan, David Bouchier-Hayes, R. I. Holdsworth, M. Ahearne, H. Abdih, S. Dolan, P. Gillen, Alfred E. Wood, John M. Fitzpatrick, R. Vashisht, M. Akram, J. A. McKeever, D. Bouchier Hayes, C. J. Kelly, K. Stokes, P. Mohan, G. Mccluggage, John Hyland, T. Creagh, S. Reid, L. S. Young, C. Malone, N. Barrett, Hannah McGee, G. R. Campbell, R. B. Stephens, M.J. Kerin, Oliver J. McAnena, G. N. Collins, M. R. Butler, J. Dolan, T. Carroll, M. P. Brady, D. Waldron, Denis Evoy, A. R. Mundy, T. V. Keaveny, S. E. A. Attwood, M. Koppikar, P. Neary, Michael Walsh, P. Kent, K. S. Cross, W. D. B. Clements, B. Bulle, N. F. Couse, N. Williams, J. M. Fitzpatrick, C. O≿herlihy, D. Maher, M. C. Regan, J. K. Lyerly, John R. Kelly, B. Boyle, G. D. Shanik, K. F. McGeeney, Thomas F. Gorey, Conor Patrick Delaney, M. Durkan, Dermot J. Moore, J. H. Wang, Stewart R. Walsh, W. P. Joyce, R. Waldron, G. Lynch, R. Grainger, T. Smalley, C. A. O. Boyle, D. Mehigan, D. Mcavinchey, J. K. Collins, W. Norwood, J. A. O≿donnell, P. Mccarthy, J. Russell, N. H. Anderson, V. S. Donnelly, J. O≿donnell, P. M. Mercer, R. W. G. Watson, Peter T. McCollum, C. P. Delaney, S. Brown, J. Barrett, S. W. Macgowan, S. Kennedy, T. Hall, N. J. O≿higgins, D. M. O≿hanlon, D. Chin, Peter A. Stonebridge, M. Morrin, John M. Daly, J. Mccann, H. Gallagher, and J. Egan
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business.industry ,Medicine ,Art history ,General Medicine ,business - Published
- 1994
- Full Text
- View/download PDF
18. 19th Sir peter freyer memorial lecture and surgical symposium 16th and 17th September 1994
- Author
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D. A. McEvoy, B. Connolly, V. Donohue, D. O’Halpin, H. Rowley, T. P. O’Dywer, C. Timon, J. A. McKeever, M. A. Stokes, J. G. Bannigan, M. J. Early, D. M. Baker, Van-Tam Nguyen, D. Bush, J. Jones, J. B. Bourke, K. S. Cross, G. Durkan, M. Stokes, T. Carroll, T. Gorey, K. O’Malley, D. Mulcahy, D. McCormack, J. McElwain, S. C. Natin, T. N. Walsh, T. P. J. Hennessy, K. Carson, R. Page, W. Blunnie, D. C. Moriarty, R. W. G. Watson, D. M. Bouchier-Hayes, H. Abdih, C. J. Kelly, M. Barry, P. Burke, A. Tanner, D. J. Bouchier-Hayes, T. O’Sullivan, A. F. Horgan, D. H. L. Chin, J. A. Mannick, M. L. Rodrick, N. Finnegan, S. T. O’Sullivan, S. F. Wolf, M. C. Barry, C. Condron, R. G. K. Watson, J. D. Evans, C. A. Maxwell-Armstrong, M. K. Barry, K. K. Singh, P. Ralston, C. D. Auld, M. Henderson, J. McCormick, A. D. F. Walls, I. Keogh, M. Kerin, D. O’Hanlon, S. Walsh, P. Kent, J. Callaghan, H. F. Given, P. Madhavan, B. Golden, F. Khan, E. Murphy, N. Couse, G. Burke, P. V. Delaney, R. McLoughlin, P. Kenny, D . O’Hanlon, H. Grimes, S. Reid, P. Neary, M. Nassralla, T. K. Neelamekam, P. Horgan, O. Traynor, P. G. Horgan, J. Hyland, D. M. O’Hanlon, C. O’Boyle, M. J. Duffy, E. W. M. McDermott, D. Reilly, J. J. Fennelly, N. J. O’Higgins, A. McNamara, H. Mullett, D. O’Riordan, E. McDermott, M. Sharp, N. O’Higgins, M. Murphy, M. Little, D. Maher, A. Khalid, P. McCarthy, I. F. Given, C. Bolger, J. P. Phillips, C. Gilligan, S. Zareb, C. Roake, D. S. O’Riordain, D. Farley, C. Grant, J. van Heerden, D. P. O’Brien, M. J. Flynn, F. B. V. Keane, B. Sweeney, D. O’Riordain, A. J. Curran, W. Joyce, D. Smith, H. Gallagher, M. A. Walsh, D. Bouchier-Hayes, J. Phillips, T. O’Brien, S. W. Yusuf, A. C. Perkins, M. Frier, P. W. Wenham, B. R. Hopkinson, G. S. Makin, R. Hind, W. Yusuf, S. C. Whitaker, R. E. Hind, T. A. M. Chuter, G. C. Durkan, M. J. Grenell, M. C. Regan, T. F. Gorey, C. F. Castineira, S. J. Sheehan, M. Wali, M. P. Colgan, D. J. Moore, G. D. Shanik, G. McGreal, J. Kelly, D. Hehir, M. P. Brady, D. M. Sibbering, P. A. M. Holland, A. R. M. Wilson, R. W. Blarney, M. Khurrum Baig, N. Mulligan, B. Farrell, F. O. Cunningham, M. Magd-Eldin, P. Keeling, Y. A. Gul, S. W. Yeo, U. D. Khan, F. Lennon, M. F. Shine, V. Kalidasan, O. Fulena, E. J. Guiney, R. J. Fitzgerald, M. Corbally, A. E. Wood, C. M. Reardon, G. T. McGreal, D. J. Hehir, J. A. O’Donnell, W. O. Kirwan, A. A. Mahomed, A. Keshgar, R. Surna, M. T. Corbally, S. O’Rourke, I. Beckingham, M. C. Bishop, J. Husain, N. Hegarty, J. Calleary, I. Rafi, M. Gilmore, S. M. Saleem, H. P. Singh, T. Aherne, H. P. Redmond, J. McCarthy, D. M. Mulcahy, P. Nicholson, P. Harrington, T. Sharif, H. Smyth, G. Fenelon, J. Pegum, J. Corrigan, A. Jenkinson, A. A. El-Magbri, M. A. Gussail, M. A. Smew, A. Martin, M. Bennett, M. A. Farrell, C. Curran, M. J. Kerin, M. T. P. Caldwell, P. J. Byrne, S. Duggan, A. S. Jones, J. K. Field, D. Monaghan, C. Condren, S. Crerand, M. Kavanagh, P. Dervan, B. Hurson, K. Aiyaswami, D. Evoy, M. Walsh, B. Garrihy, S. Kaf Al-Ghazal, J. O’Donoghue, J. McCann, S. Wagstaff, C. Conroy, M. Dolan, L. Smith, L. Klenerman, J. Noel, V. Waide, D. O’Sullivan, C. Biyani, C. Powell, M. Heal, R. Surana, A. Khan, T. Lynch, T. Sami, W. Baluch, D. Hickey, M. Donovan, P. McLean, D. Murphy, S. Johnston, V. Rastogi, J. Doyle, J. R. Flynn, P. Kelly, M. F. Neligan, S. W. MacGowan, O. Sharkey, A. Bhojwani, C. Barry Walsh, E. Kay, C. Milbum, M. Leader, J. McDermott, D. Moriarty, P. Caushaj, J. M. Fitzpatrick, D. Byrne, W. P. Hederman, N. K. O’Malley, K. H. Chan, P. Fleming, G. C. O’Sullivan, K. Aizaz, A. F. O’Donnell, D. A. Luke, E. M. McGovern, N. Patil, P. Gormley, and P. M. McCarthy
- Subjects
medicine.medical_specialty ,business.industry ,medicine ,Physiology ,Medical physics ,General Medicine ,Session (computer science) ,business - Published
- 1994
- Full Text
- View/download PDF
19. Seventeenth Sir Peter Freyer memorial lecture and surgical symposium
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E. O’Broin, J. Donohoe, K. Mealy, M. Kerin, P. Gillen, W. A. Tanner, F. B. V. Keane, P. McCarthy, S. Rubesin, H. Herlinger, I. Laufer, M. T. P. Caldwell, P. Lawlor, P. J. Byrne, T. N. Walsh, T. P. J. Hennessy, A. J. Curran, P. Gormley, K. Barry, M. McGuire, P. Marks, A. Syed Asad, B. Lane, H. I. Browne, P. Keeling, M. K. Barry, C. J. Yeo, P. K. Sauter, K. D. Lillemoe, H. A. Pitt, J. L. Cameron, S. Sostre, D. A. O’Donovan, C. J. Kelly, D. M. Bouchier-Hayes, H. P. Redmond, P. Burke, W. S. Monkhouse, J. Burke, N. Williams, T. Gorey, N. H. Afdhal, A. I. Butt, M. H. Vazir, R. Sullivan, C. E. Connolly, H. C. Bredin, J. P. Sweeney, D. Greene, R. Harkin, J. Thornton, M. R. Butler, T. E. D. McDermott, R. Grainger, J. Thornhill, M. J. Kerin, J. Wilkie, J. R. T. Monson, S. Duggan, J. McCarthy, R. G. W. Watson, D. T. Croke, M. McDermott, D. Croke, P. B. V. Keane, R. W. G. Watson, R. O’Donnell, A. F. Horgan, D. S. O’Riordain, I. Saporoschetz, J. A. Mannick, M. L. Rodrick, D. M. Baker, J. A. Jones, J. S. Nguyen-Van-Tam, D. L. Morris, J. D. Hardcastle, R. J. C. Steele, J. B. Bourke, J. H. Lloyd, S. Brown, S. E. A. Attwood, J. McGrath, M. Regan, S. McCann, R. B. Stephens, A. T. Devitt, T. J. O’Sullivan, B. J. Hurson, M. C. Regan, M. Hurson, S. J. Kirk, H. L. Wasserkrug, A. Barbul, E. R. Naidu, Tracy Sullivan, M. Colreavy, S. Kaf Al-Ghazal, J. McCann, M. Rodrick, K. J. Cronin, P. Butler, M. McHugh, G. Edwards, J. G. Geoghegan, D. J. Hehir, W. O. Kirwan, M. P. Brady, J. A. O’Donnell, D. Evoy, S. T. O’Sullivan, C. M. Reardon, M. A. Stokes, F. Bergin, P. Mercer, D. Murphy, N. O’Higgins, P. M. Cannon, J. F. R. Robertson, I. O. Ellis, R. W. Blarney, D. L. Manning, R. I. Nicolson, E. Mulligan, P. Kent, J. Ennis, M. Dowling, P. Dervan, J. M. Fitzpatrick, T. F. Gorey, D. M. Sibbering, M. H. Galea, D. A. L. Morgan, A. P. Locker, C. W. Elston, R. W. Blamey, S. P. M. Cannon, S. O’Rourke, M. Galea, A. Evans, I. Ellis, S. Johnston, J. Byrne, P. Horgan, M. Kennedy, J. Callaghan, H. F. Given, E. Mooney, S. Donohue, D. M. O’Hanlon, R. Waldron, J. Johnston, M. Stokes, E. MeDermott, M. Sharp, M. Duffy, J. Murphy, G. T. McGreal, W. Kealy, M. Neligan, K. O’Malley, G. McEntee, F. Khan, M. Morrin, P. Delaney, N. Brindley, S. Dudeney, J. Drebin, J. Geraghty, P. Broe, M. Fynes, P. G. Horgan, P. R. O’Connell, B. Golden, F. Loughnane, S. Baldota, M. O’Donnell, S. Chen, P. W. Eustace, J. G. Johnston, T. Gaffney, S. El Tawil, F. Cunningham, E. Brazil, J. Reynolds, A. Ireland, O. Traynor, D. Little, M. Barry, F. Thornton, S. Sheehan, D. J. Bouchier-Hayes, P. Fitzgerald, P. Grace, Y. Gul, D. Waldron, M. Wali, M. P. Colgan, D. J. Moore, D. G. Shanik, J. MacNamara, V. P. Lynch, H. Abdih, W. Watson, J. D. Aloisi, T. J. Boyle, H. Kim Lyerly, C. Kelly, D. O’Donovan, W. Monkhouse, J. M. O’Donoghue, C. Curran, D. O’Hanlon, D. Maher, C. Homer, M. O’Brien, M. Caldwell, R. Sheehan, P. Crean, T. O’Brien, C. Grant, J. A. Van Heerden, J. A. Lynn, B. G. O’Donovan, D. S. Quill, C. P. Delaney, J. Phillips, J. A. McKeever, M. J. Earley, A. C. B. Hooper, S. K. Al-Ghazal, K. Khan, M. McKiernan, R. McQuillan, J. R. McCabe, D. O’Farrell, J. O’Byrne, B. O’Donovan, I. Rafi, M. Gilmore, F. Fitzgerald, R. Moran, D. O’Brien, C. Pidgeon, S. Young, D. Allcutt, D. Rawluk, D. P. O’Brien, J. P. Phillips, I. Beckingham, M. Hinwood, K. Rigg, M. Bishop, H. Rowley, T. P. O’Dwyer, I. J. Beckingham, J. S. O’Rourke, M. J. S. Dennis, P. R. F. Bell, M. L. Nicholson, N. Akhtar, M. O. Corcoran, T. H. Lynch, G. Connellan, D. Mulvin, B. Boyle, M. O’Donoghue, Y. El-Tayeb, J. O’Donoghue, L. Parke, D. A. Evoy, S. E. Attwood, P. W. N. Keeling, J. Doyle, J. R. Flynn, J. Hurley, A. E. Wood, C. Duncan, A. Quershi, A. Leahy, D. Hayes, H. Osborne, H. Mashali, and R. G. K. Watson
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business.industry ,Medicine ,General Medicine ,business ,Classics - Published
- 1994
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20. Iterative closest point algorithm with anisotropic weighting and its application to fine surface registration
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Lena Maier-Hein, Alfred M. Franz, T. R. Dos Santos, Hans-Peter Meinzer, and J. M. Fitzpatrick
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Surface (mathematics) ,symbols.namesake ,Computer science ,Gaussian noise ,Isotropy ,symbols ,Iterative closest point ,Point (geometry) ,Point set registration ,Polygon mesh ,Algorithm ,Rigid transformation ,Weighting - Abstract
The Iterative Closest Point (ICP) algorithm is a widely used method for geometric alignment of 3D models. Given two roughly aligned shapes represented by two point sets, the algorithm iteratively establishes point correspondences given the current alignment of the data and computes a rigid transformation accordingly. It can be shown that the method converges to an at least local minimimum with respect to a mean-square distance metric. From a statistical point of view, the algorithm implicitly assumes that the points are observed with isotropic Gaussian noise. In this paper, we (1) present the first variant of the ICP that accounts for anisotropic localization uncertainty in both shapes as well as in both steps of the algorithm and (2) show how to apply the method for robust fine registration of surface meshes. According to an evaluation on medical imaging data, the proposed method is better suited for fine surface registration than the original ICP, reducing the target registration error (TRE) for a set of targets located inside or near the mesh by 80% on average.
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- 2011
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21. Irish Society of Gastroenterology
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J. Coleman, D. Bouchier Hayes, M. A. Daw, R. O’More, C. T. Keane, C. O’Morain, G. W. Johnson, E. F. A. Spencer, A. J. Wilkinson, T. L. Kennedy, J. S. A. Collins, K. B. Bamford, B. J. Collins, J. M. Sloan, R. J. Moorehead, A. H. G. Love, C. McCarthy, R. Collins, S. Beattie, J. McDevitt, C. Feighery, C. O’Farrelly, D. G. Weir, D. Kelleher, A. Whelan, Y. Williams, D. Kellegher, D. Weir, M. C. Prabhakar, M. Daw, F. Keane, E. W. M. McDermott, B. Duduric, M. F. Brennan, R. Gaffney, J. O’Leary, T. Doyle, A. Gaffney, D. B. Gough, K. C. H. Fearon, P. Winstanley, D. C. Carter, O. J. McAnena, F. A. Moore, E. E. Moore, R. Pogetti, V. M. Peterson, C. M. Abemathy, P. Parsons, N. N. Williams, J. M. Daly, M. Herlyn, D. Bouchier-Hayes, N. F. Course, P. G. Horgan, A. Fahy, C. Delaney, J. M. Fitzpatrick, T. F. Gorey, S. Jazrawl, T. N. Walsh, P. J. Byrne, P. Lawlor, T. P. J. Hennessy, K. R. O’Sullivan, P. M. Mathias, M. McNicholas, M. Logan, J. Masterson, P. Gillen, J. Hyland, E. Beausang, W. P. Joyce, N. Williams, W. Maxwell, I. Reid, I. Sharpe, J. G. Geraghty, W. A. Tanner, S. Patchett, H. Mulcahy, N. Afdhal, D. O’Donoghue, A. Lohan, A. Darzi, F. B. V. Keane, P. W. N. Keeling, R. C. Gibney, R. Keane, J. Drumm, T. J. Egan, P. V. Delaney, G. O’Sullivan, P. Harte, P. A. Grace, A. Qureshi, H. Osbome, D. J. Bouchier-Hayes, S. L. Bamford, J. Geraghty, F. B. Keane, J. E. Coleman, A. Gleeson, K. Mealy, M. Barry, O. Traynor, J. J. Keating, A. Chua, S. Ah-Kion, J. McNulty, L. G. Heaney, P. Murphy, J. H. Connolly, M. E. Callender, P. MacMathuna, M. Farrant, D. O. B. Hourihane, P. Donaldson, M. Lombard, D. Westaby, Roger Williams, N. F. Couse, J. Burke, G. Lennon, C. P. Delaneyc, S. O’Brien, A. O’Brien, M. X. Fitzgerald, J. E. Hegarty, N. Noonan, M. Healy, R. O’Moore, O. I. Corrigan, P. W. N. Keating, H. U. I. Li, R. C. Stuart, S. Jazrawi, D. Wai, H. Jaeger, A. M. Jackson, C. J. Mitchell, J. MacFie, C. P. Delaney, K. McGeeney, M. T. P. Caldwell, D. P. O’Donoghue, J. Connolly, E. Kay, T. Gorey, P. McKiernan, J. F. T. Glasgow, B. T. Johnson, R. Ferguson, I. Davidson, J. Hurley, P. Keeling, T. Crowley, A. A. Long, D. P. O’Brien, R. P. Waldron, M. J. Shearer, H. F. Given, G. McEntee, J. Monson, J. Donohue, D. Nagomey, K. C. Trimble, A. M. Molloy, J. M. Scott, J. McKeever, and T. P. J. Hennessey
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Irish ,business.industry ,language ,Medicine ,Library science ,General Medicine ,business ,language.human_language - Published
- 1993
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22. The West Pacific diversity hotspot as a source or sink for new species? Population genetic insights from the Indo-Pacific parrotfish Scarus rubroviolaceus
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J M, Fitzpatrick, D B, Carlon, C, Lippe, and D R, Robertson
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Gene Flow ,Population Density ,Pacific Ocean ,Genotype ,Genetic Speciation ,Population Dynamics ,Genetic Variation ,Perciformes ,Mutation ,Animals ,Animal Migration ,Metagenomics ,Indian Ocean ,Phylogeny ,Microsatellite Repeats - Abstract
We used a population genetic approach to quantify major population subdivisions and patterns of migration within a broadly distributed Indo-Pacific parrotfish. We genotyped 15 microsatellite loci in Scarus rubroviolaceus collected from 20 localities between Africa and the Americas. A STRUCTURE model indicates the presence of four major populations: Eastern Pacific, Hawaii, Central-West Pacific and a less well-differentiated Indian Ocean. We used the isolation and migration model to estimate splitting times, population sizes and migration patterns between sister population pairs. To eliminate loci under selection, we used BayeScan to select loci for three isolation and migration models: Eastern Pacific and Central-West Pacific, Hawaii and the Central-West Pacific, and Indian Ocean and the Central-West Pacific. To test the assumption of a stepwise mutation model (SMM), we used likelihood to test the SMM against a two-phase model that allowed mutational complexity. A posteriori, minor departures from SMM were estimated to affect ≤2% of the alleles in the data. The data were informative about the contemporary and ancestral population sizes, migration rates and the splitting time in the eastern Pacific/Central-West Pacific comparison. The model revealed a splitting time ∼17,000 BP, a larger contemporary N(e) in the Central-West Pacific than in the eastern Pacific and a strong bias of east to west migration. These characteristics support the Center of Accumulation model of peripatric diversification in low-diversity peripheral sites and perhaps migration from those sites to the western Pacific diversity hotspot.
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- 2010
23. Accounting for anisotropic noise in fine registration of time-of-flight range data with high-resolution surface data
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L, Maier-Hein, M, Schmidt, A M, Franz, T R, dos Santos, A, Seitel, B, Jähne, J M, Fitzpatrick, and H P, Meinzer
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Imaging, Three-Dimensional ,Image Interpretation, Computer-Assisted ,Humans ,Reproducibility of Results ,Artifacts ,Image Enhancement ,Sensitivity and Specificity ,Algorithms - Abstract
Time-of-Flight (ToF) sensors have become a considerable alternative to conventional surface acquisition techniques such as laser range scanning and stereo vision. Application of ToF cameras for the purpose of intra-operative registration requires matching of the noisy surfaces generated from ToF range data onto pre-interventionally acquired high-resolution surfaces. The contribution of this paper is twofold: Firstly, we present a novel method for fine rigid registration of noisy ToF data with high-resolution surface meshes taking into account both, the noise characteristics of ToF cameras and the resolution of the target mesh. Secondly, we introduce an evaluation framework for assessing the performance of ToF registration methods based on physically realistic ToF range data generated from a virtual scence. According to experiments within the presented evaluation framework, the proposed method outperforms the standard ICP algorithm with respect to correspondence search and transformation computation, leading to a decrease in the target registration error (TRE) of more than 70%.
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- 2010
24. THE ROLE OF LIVESTOCK KEEPING IN HUMAN BRUCELLOSIS TRENDS IN LIVESTOCK KEEPING COMMUNITIES IN TANZANIA
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Sarah Cleaveland, Rudovick Kazwala, J. M. Fitzpatrick, J Kunda, Godfrey S Mfinanga, Dominic M. Kambarage, Gabriel M. Shirima, and DFID-UK
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medicine.medical_specialty ,Veterinary medicine ,Keywords: Undulant Fever ,Livestock brucellosis ,Pastoralists ,Agropastoralists ,biology ,business.industry ,Public health ,Pastoralism ,Prevalence ,Brucellosis ,General Medicine ,medicine.disease ,biology.organism_classification ,Tanzania ,parasitic diseases ,Epidemiology ,medicine ,Seroprevalence ,Livestock ,Socioeconomics ,business - Abstract
A cross-sectional survey was carried out in Karatu and Ngorongoro districts in Arusha region and Babati, Hanang and Mbulu districts in Manyara region involving 20 agro-pastoral and 9 pastoral villages, to establish the magnitude of human brucellosis in relation to livestock brucellosis. A multistage random sampling was used to select villages, sub-village administrative units, ten cell leadership units and animal keeping households. A total of 460 humans from 90 families (19 pastoral and 71 agro-pastoral families) and 2723 domestic ruminants from 90 livestock households were sampled and bled to obtain serum samples for analysis. A competitive enzyme linked-immunosorbent assay (c-ELISA) was used to analyse these samples to detect brucella circulating antibodies. The overall livestock seroprevalence was 5.7% with 32.2% of livestock households being seropositive whereas, human seropositivity was 8.3% with 28% family households being seropositive. The highest proportion of seropositive families was observed in Ngorongoro district (46%) and the lowest in Babati district with no seropositive family household. Family members in seropositive livestock households were 3.3 (OR) times more likely to be seropositive than those with seronegative livestock households. However; 25% of seronegative family households had seropositive livestock households and 48% seropositive family households had seronegative livestock households. Therefore, Brucella infection is widespread in the human populations and their livestock in the northern Tanzania and thus humans may acquire infection from their own animals or from other sources thus prompted public health awareness creation in such communities.
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- 2010
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25. A rare benign renal tumour presenting as polycythaemia in a teenage girl
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S, Geoghegan, J M, Fitzpatrick, B, McGuire, K J, O'Malley, C, Shaw, and A, Fabre
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Adenoma ,Adolescent ,Humans ,Female ,Polycythemia ,Tomography, X-Ray Computed ,Kidney Neoplasms - Abstract
We present the case of a 15-year-old girl who presented with polycythemia. CT abdomen revealed an enhancing mass in the upper pole of her left kidney with features suggestive of renal cell carcinoma. She underwent a laparoscopic radical nephrectomy. Histology demonstrated a well circumscribed, focally encapsulated, round blue cell tumour showing areas of microcalcifications and numerous psammoma bodies. Imunostaining showed diffuse positive staining for CD 57. This was consistent with a diagnosis of metanephric adenoma a rare benign epithelial renal tumour.
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- 2010
26. The Role of Registration in Accurate Surgical Guidance
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J M Fitzpatrick
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Models, Statistical ,Point registration ,Computer science ,business.industry ,Mechanical Engineering ,Frame (networking) ,General Medicine ,Article ,Surface matching ,Surgery, Computer-Assisted ,Image Processing, Computer-Assisted ,Humans ,Point (geometry) ,Computer vision ,Artificial intelligence ,Focus (optics) ,Guidance system ,Fiducial marker ,business ,Head ,Algorithms - Abstract
Registration is presented as the central issue of surgical guidance. The focus is on the accuracy of approaches employed today, all of which use pre-operative images to guide surgery on rigid anatomy. The three most well-established approaches to guidance, namely the stereotactic frame, point fiducials, and surface matching, are examined in detail, together with two new approaches based on microstereotactic frames. It is shown that each method relies on the registration of points in the image to corresponding points in the operating room, and therefore that the error patterns associated with point registration are similar for all of them. Three types of registration error, namely fiducial localization error (FLE), fiducial registration error (FRE), and target registration error (TRE), are highlighted, as well as two additional guidance errors, namely target localization error and total targeting error, the latter of which is the overall error of the guidance system. Statistical relationships between TRE and FLE, between FRE and FLE, and between TRE, TLE, and TTE are given. Finally some myths concerning fiducial registration are highlighted.
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- 2010
27. Irish society of gastroenterology
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A. Brannigan, N. N. Williams, M. Grahn, N. S. Williams, J. M. Fitzpatrick, P. R. O’Connell, C. V. Soong, P. Blair, M. I. Halliday, J. M. Hood, B. J. Rowlands, A. A. B. Barros D’sa, R. J. Cahill, S. Beattie, H. Hamilton, C. O’Morain, S. J. Kelly, K. E. O’Malley, W. A. Stack, D. O’Donoghue, A. W. Baird, K. J. Cronin, M. J. Kerin, J. Crowe, P. MacMathuna, J. Lennon, T. F. Gorey, A. Chua, V. O’Kane, T. G. Dinan, P. W. N. Keeling, E. Mulligan, K. L. Cronin, P. Dervan, A. Ireland, D. Murphy, G. O’Sullivan, E. Ryan, P. Kelly, J. Gilvarry, S. Sant, X. J. Fan, C. N. Shahi, M. O’Connell, D. G. Weir, D. Kelleher, J. McDevitt, J. M. O’Donoghue, P. G. Horgan, W. J. Byrne, M. McGuire, H. F. Given, M. A. Daw, P. Kavanagh, P. O’Mahony, T. Joy, F. Gleeson, A. Mullan, M. Gibney, Anne Mannion, F. M. Stevens, C. F. McCarthy, A. A. Killeen, P. M. Murchan, J. V. Reynolds, N. Leonard, P. Marks, F. B. V. Keane, W. A. Tanner, M. A. O’Connell, B. Corridan, R. Collins, R. Shannon, R. Cahill, W. P. Joyce, M. Goggin, J. Hyland, O. Traynor, A. Qureshi, M. DaCosta, N. Brindley, P. Burke, P. Grace, D. Bouchier-Hayes, A. L. Leahy, G. Courtney, H. Osbome, N. O’Donovan, M. O’Donoghue, J. K. Collins, D. Morrissey, J. E. McCarthy, H. P. Redmond, A. D. K. Hill, P. A. Grace, H. Naama, O. M. Austin, D. M. Bouchier-Hayes, J. M. Daly, D. Breslin, C. P. Delaney, S. T. O’Sullivan, G. C. O’Sullivan, W. O. Kirwan, C. D. Weir, L. T. McGrath, S. Maynard, N. H. Anderson, C. Gokulan, T. A. O’Gorman, E. Breshihan, Pin Yin Lam, R. Skehill, H. Grimes, J. A. McKeever, M. A. Stokes, D. Mehigan, T. V. Keaveny, J. Meehan, A. Molloy, C. Q’Farrelly, J. Scott, M. S. Dudeney, A. Leahy, P. A. Grace., G. McEntee, N. D. Hcaton, V. Douglas, R. Mondragon, J. O’Grady, R. Williams, K. C. Tan, H. X. Xia, C. T. Keane, C. A. O’Morain, A. O’Mahony, A. Corbett, P. Harte, H. Mulcahy, S. Patchett, W. Stack, M. Gallagher, K. Connolly, J. Doyle, J. R. Flynn, M. Maher, D. Hehir, A. Horgan, R. Stuart, M. P. Brady, P. W. Johnston, B. T. Johnston, B. J. Collins, J. S. A. Collins, A. H. G. Love, S. G. Marshall, T. G. Parks, R. A. J. Spence, H. J. O’Connor, K. Cunnane, M. Duggan, P. MacMalhuna, M. Kerin, S. E. A. Attwood, L. Viani, M. Jeffers, T. N. Walsh, P. J. Byrne, I. Frazer, T. P. J. Hennessy, G. L. Hill, W. Dickey, S. A. McMillan, C. Bharucha, K. G. Porter, H. Rolfe, J. Thornton, J. Coleman, R. B. Stephens, S. Hone, K. Holmes, I. P. Kelly, T. P. Corrigan, D. McCrory, M. McCaigue, G. R. Barclay, M. Quirke, J. E. Hegarty, D. P. O’Donoghue, D. O’Hanlon, and J. Byrne
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medicine.medical_specialty ,Irish ,business.industry ,Ophthalmology ,language ,Medicine ,Library science ,General Medicine ,business ,language.human_language - Published
- 1992
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28. Sixteenth sir peter freyer memorial lecture and surgical symposium September 13th & 14th, 1991 Session I
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J. Coulter, R. G. Molloy, K. T. Moran, R. Waldron, W. O. Kirwan, C. O’Suilleabhain, A. Horgan, K. Mealy, P. Burke, J. Hyland, A. F. Horgan, M. Sheehan, R. M. Browne, O. Austin, A. P. Clery, J. M. Deasy, S. Sulaiman-Shoaib, J. Soeda, D. S. O’Briain, P. Puri, E. C. Coveney, V. McAllister, E. W. M. McDermott, N. J. O’Higgins, M. Maher, M. T. P. Caldwell, P. Murchan, W. Beesley, T. M. Feeley, W. A. Tanner, F. B. V. Keane, F. Abbasakoor, S. E. A. Attwood, L P. McGrath, R. B. Stephens, E. O’Broin, M. G. Davies, J. McGinley, C. Mannion, S. Gupta, M. F. Shine, F. Lennon, G. Ninan, R. J. Fitzgerald, E. J. Guiney, B. O’Donnell, A. F. O’Donnell, D. Luke, A. E. Wood, P. G. Murphy, T. N. Walsh, A. D. K. Hill, H. Li, T. P. J. Hennessy, N. Noonan, B. Breslin, P. W. N. Keeling, A. J. Curran, D. B. Gough, I. R. Davidson, P. Keeling, D. P. O’Leary, A. Smythe, N. C. Bird, A. G. Johnson, P. Nicholson, O. Traynor, K. Dawson, J. Aitken, B. A. Cooke, S. P. Parbhoo, N. N.Williams, J. M. Daly, M. Herlyn, D. Bouchier-Hayes, R. C. Stuart, M. J. Allen, W. D. Thompson, A. L. G. Peel, D. T. Hehir, K. Cronin, A. McCann, P. A. Dervan, S. J. Heffernan, W. P. Hederman, M. H. Galea, B. Dilks, A. Gilmour, L. O. Ellis, C. W. Elston, R. W. Blarney, S. O’Rourke, A. Mookens, R. Carter, D. Parkin, N. F. Couse, C. P. Delaney, P. G. Horgan, J. M. Fitzpatrick, T. F. Gorey, J. M. O’Byrne, J. P. McCabe, M. Stephens, F. McManus, J. L.Mangan, D. A. Barr, G. J. Mulvenna, P. Maginn, W. G. Kernohan, R. A. B. Mollan, S. J. O’Flanagan, J. P. Stack, P. Dervan, B. Hurson, S. Tierney, P. Fitzgerald, T. O’Sullivan, P. Grace, J. P. Wyatt, R. J. Evans, S. P. Cusack, S. McGowan, E. McGovem, S. D. Schwaitzberg, R. J. Connolly, R. P. Sullivan, G. Mortimer, J. G. Geraghty, P. J. O’Dwyer, B. S. McGlone, D. P. O’Brien, H. A. Younis, H. F. Given, C. Phelan, J. Byrne, K. Barry, D. Gough, L. Hanrahan, F. Given, J. P. Sweeney, A. M. Korebrits, J. V Reynolds, T. F Gorey, D. M. O’Hanlon, M. A. Stokes, H. P. Redmond, J. McCarthy, P. Losty, M. Murphy, P. E. M. Butler, P. G. Grace, J. R. Novell, S. K. Hobbs, O. Smith, G. Hazlehurst, B. Brozovic, K. Rolles, A. Burroughs, S. Mallett, A. Mehta, D. Buckley, D. Waldron, D. O’Brien, C. Curran, L. Grey, A. Leahy, A. Darzi, D. Leader, P. Broe, J. G. Geoghegan, C. A. Cheng, D. C. Lawson, T. N. Pappas, D. O’Sullivan, M. M. Lieber, T. V Colby, D. M. Barrett, E. Rogers, J. Greally, H. C. Bredin, M. O. Corcoran, M. Kenny, P. Horgan, D. Headon, A. Grace, P. A. Grace, S. Cross, D. Hehir, S. O’Briain, P. Hartigan, M. P. Colgan, D. Moore, G. Shanik, S. Z. Zaidi, D. J. Hehir, K. S. Cross, D. J. Moore, D. G. Shanik, P. Lacy, J. E. Coleman, C. S. McEnroe, J. A. Gelfand, T. F. O’Donnell, A. D. Callow, D. J. Buckley, D. S. O’Riordain, J. A. O’Donnell, P. Meagher, K. Boos, P. Gillen, T. Corrigan, R. Vashisht, M. Sian, E. J Sharp, M. K. O’Malley, M. J. Kerin, D. Wilkinson, A. Parkin, R. C. Kester, M. M. Maher, R. P. Waldron, D. J. Waldron, M. P. Brady, M. Allen, T. H Lyncy, B. Waymont, L. Emtage, G. R. Blackledge, M. A. Hughes, D. M. A. Wallace, L. Mynderse, H. Grimes, F. Chambers, D. Lowe, B. Prasad, D. C. O’Sullivan, M. Barry P. Gillen, M. McNicholas, H. Bredin, T. H. O’Dowd, M. Corcoran, J. M. O’Donoghue, M. McGuire, A. McNamara, T. Creagh, R. Grainger, T. B. D. McDermott, M. R. Butler, M. Gleeson, T. E. D. McDermott, J. P. Hurley, R. Hone, M. Neligan, J. Hurley, M. White, P. McDonagh, D. Phelan, E. McGovern, F. Quinn, F. Breatnach, A. O’Meara, J. P. McGrath, S. R. McCann, E. F. Gaffney, A Hennessy, M. Leader, F. S. Taleb, M. V. McKiernan, P. J. Leyden, J. J. McCann, J. Coleman, A. Quereshi, N. Ajayi, G. McEntee, H. Osborne, D. J. Bouchier-Hayes, S. Johnston, K. O’Malley, E. Smyth, D. L Bouchier-Hayes, P. R. O’Connell, T. Gorey, O. J. McAnena, M. W. Reed, J. L. Duncan, C. S. Reilly, C. McGibney, P. Lawlor, B. Lawless, E. McGuinness, and S. Leahy
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business.industry ,Medicine ,General Medicine ,Session (computer science) ,business ,Classics - Published
- 1992
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29. Irish society of gastroenterology
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L. A. Cotter, M. Healy, M. Buckley, C. O’Morain, C. Keane, R. R. O’Moore, W. Dickey, G. Roberts, G. Orr, K. Porter, D. McCrory, M. I. Halliday, M. Hoper, A. Crockard, B. J. Rowlands, A. Chua, T. Dinan, B. Dunbar, D. G. Weir, P. W. N. Keeling, B. T. Johnston, J. S. A. Collins, R. J. McFarland, A. H. G. Love, A. Darzi, C. T. N. Speakman, A. Spigelman, M. M. Henry, W. A. fnTanner, G. P. fnMcEntee, F. B. fnKeane, O. Tighe, M. Bennett, H. Mulcahy, N. N. Williams, J. P. Duignan, D. Bouchier-Hayes, D. O’Donoghue, D. T. Croke, A. D. Hill, T. N. Walsh, T. P. J. Hennessy, M. Goggin, W. P. Joyce, C. Prendergast, E. Gibney, O. J. Traynor, J. Hyland, S. O’Brien, M. X. Fitzgerald, J. E. Hegarty, A. Leahy, P. Grace, A. Qureshi, M. Leader, P. Broe, S. Eustace, N. Blake, J. McDevitt, C. F. Feighery, C. O’Farrelly, D. Kelleher, M. A. O’Connell, M. A. Stokes, G. L. Hill, P. Gaffney, J. O’Leary, C. Doyle, J. Hogan, Anne Gaffney, S. E. A. Attwood, P. Murphy, R. B. Stephens, R. H. Wilson, R. Gilliland, F. Kee, J. M. Sloan, R. J. Moorehead, G. ’Suilleabhain, A. Horgan, W. O. Kirwan, G. T. Deans, M. Heatley, K. Williamson, T. G. Parks, B. J. Rowland, R. A. J. Spence, K. Mealy, P. Burke, M. Herlyn, H. P. Redmond, A. P. Clery, J. M. Deasy, O. Austin, J. Meenan, R. J. Canili, P. M. Mathias, S. Beattie, H. Hamilton, J. G. Geoghegan, C. A. Cheng, D. C. Lawson, T. N. Pappas, R. Collins, S. Beatie, J. K. Collins, G. O’Sullivan, A. Corbett, W. D. B. Clements, P. MacMathuna, M. Lombard, A. Gimson, D. Westaby, R. Williams, M. Duggan, J. Lennon, J. Crowe, A. J. Ritchie, F. Johnston, J. McGuigan, J. R. P. Gibbons, K. D. Buchanan, J. M. Gilvarry, R. Robinson, J. F. Fielding, M. Lawler, P. Humphries, O. Sheils, D. S. O’Briain, J. McCarthy, M. McDermott, D. Hourihane, H. Gallagher, M. Barry, F. Lennon, W. P. Hederman, P. R. O’Connell, T. F. Gorey, J. M. Fitzpatrick, J. M. Daly, J. E. Carthy, H. Redmond, D. Croake, P. A. Grace, G. Campbell, O. Maguire, S. Lynch, J. Atwood, L. Madrigal, J. Attwood, A. Murphy, P. Shovlin, J. Hegarty, V. Egleston, D. P. MacErlean, S. Johnston, K. O’Malley, G. McEntee, E. Smyth, B. Moran, G. Plant, M. Rees, N. Brindley, H. Osborne, B. Lane, G. Lynch, J. Geraghty, D. Murphy, M. O’Brien, and P. Harte
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Irish ,business.industry ,language ,Library science ,Medicine ,General Medicine ,business ,language.human_language - Published
- 1992
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30. Fifteenth Sir Peter Freyer Memorial Lecture and Surgical Symposium Proceedings of meeting held 14th & 15th September, 1990 at University College, Galway
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C. Bolger, G. Fry, D. Coakley, J. Philips, N. Sheahan, J. Malone, W. P. Gray, M. O’Sullivan, T. F. Buckley, T. P. O’Dwyer, P. J. Gullane, B. P. Kneafsey, K. T. Moran, S. T. O’Sullivan, M. P. Brady, E. C. Coveney, J. G. Geraghty, N. J. O’Higgins, J. O’Beirne, P. Seighe, J. P. McElwain, J. P. McCabe, B. Waldron, J. Byme, N. Hickey, J. McCabe, J. McMahon, J. Colville, B. J. Moran, R. A. Frost, M. J. Kerin, J. J. Jaeger, C. J. Mitchell, J. MacFie, T. O’Hanrahan, N. A. Scott, D. Leinhardt, M. H. Irving, D. Gough, M. White, M. Morrin, W. Joyce, D. Phelan, J. Fitzpatrick, T. Gorey, D. Wilkinson, A. Parkin, R. C. Kester, E. J. Gibney, K. McGrath, A. J. Cunningham, D. Bouchier-Hayes, M. Barry, M. Farrell, W. Monkhouse, K. J. Dawson, D. Hehir, G. Hamilton, P. A. Grace, A. Quereschi, R. Keane, P. Broe, G. Stansby, B. Fuller, A. Connolly, J. O’Donnell, D. Little, R. M. Keane, M. Regan, P. G. Horgan, C. Curran, D. O’Brien, D. Waldron, E. Mooney, J. Greally, H. F. Given, M. J. Duffy, D. Reilly, E. Coveney, J. Geraghty, J. J. Fennelly, N. O’Higgins, C. M. O’Hare, P. L. Jones, T. A. Zoma, G. P. Hemstreet, R. G. Postier, J. E. Coleman, E. L. Chaikof, E. W. Merrill, A. D. Callow, N. N. Williams, J. M. Daly, M. Herlyn, R. Gaffney, M. Walsh, D. McShane, C. Timon, D. Hamilton, J. Connolly, P. J. Byrne, R. B. Stuart, E. Kay, T. P. J. Hennessy, D. P. O’Leary, M. Booker, T. E. Scott, W. W. LaMorte, J. G. Geraty, W. A. Angerson, D. C. Carter, J. Lyons, A. Stack, J. M. Fitzpatrick, C. Kelly, C. Augustine, J. Kennedy, T. Creagh, D. Mannion, P. Seigne, G. Fitzpatrick, M. Feeley, P. Butler, P. Grace, M. Leader, B. Curren, C. Barry-Walsh, R. Waldron, M. Shearer, S. O’Rourke, M. Galea, A. Gilmour, R. Carter, D. Parkin, R. W. Blarney, D. J. Hehir, S. P. Parbhoo, N. Rothnie, J. Crowe, C. Wells, F. Sherry, P. O’Grady, J. Byrne, S. England, J. O’Callaghan, H. Grimes, Ursula Mulcahy, P. P. A. Smyth, V. McAlister, M. J. Murray, M. J. O’Higgins, R. O. Laoide, J. B. Hourihane, E. F. Mooney, C. Brougham, D. R. Headon, C. Coleman, E. C. Coveny, S. Jazawi, T. N. Walsh, P. Lawlor, H. Li, H. Sanfey, W. P. Joyce, D. B. Gough, P. V. Delaney, T. F. Gorey, S. E. A. Attwood, A. Watson, E. Rogers, R. P. Waldron, G. Glynn, K. U. El-Bouri, J. Flynn, P. Keeling, M. G. Davies, J. Lavelle, M. F. Shine, F. Lennon, R. C. Stewart, T. P. Hennessy, M. V. McKiernan, J. G. Johnston, L. Hanrahan, H. C. Bredin, M. O. Corcoran, M. Norton, R. Flynn, M. Gleeson, R. Grainger, T. E. D. McDermott, D. Lanigan, P. McLean, B. Curran, M. J. Gleeson, D. P. Griffin, H. J. Gallagher, T. A. Creagh, D. M. Mulvin, M. G. Donovan, D. M. Murphy, P. A. McLean, D. W. Mulvin, A. O’Brien, K. L. O’Flynn, R. McDonagh, D. G. Thomas, T. H. Lynch, P. Anderson, A. T. M. Vaughan, R. P. Beaney, D. M. A. Wallace, L. Solomon, D. S. O’Riordain, P. R. O’Connell, W. O. Kirwan, Hui Li, R. C. Stuart, S. Jazrawi, T. N. Koh, S. J. Sheehan, J. McKeever, J. Donohoe, M. Carmody, D. H. Osborne, D. E. Waldron, E. Rodgers, F. Patel, P. Horgan, M. Corcoran, K. Walsh, J. M. O’Donoghue, O. J. McAnena, M. McGuire, J. Smyth, G. Keye, A. Bahadursingh, C. Delaney, A. J. Richie, J. R. P. Gibbons, M. Marples, J. Banacewicz, H. Troidl, L. Cassidy, E. J. Prenderville, P. E. Burke, M. -.P Colgan, B. L. Wee, D. J. Moore, G. D. Shanik, K. S. Cross, M. El-Sanadiki, J. J. Murray, E. Mikat, R. McCann, P. -O. Hagen, T. R. Cheatle, E. Steibe, P. D. Colebridge Smith, J. H. Scurr, K. Barry, E. Bresnihan, D. F. Courtney, D. S. Quill, D. Buckley, D. S. O’Riordan, J. A. O’Donncll, J. A. O’Donnell, A. D. K. Hill, P. J. O’Dwycr, D. P. MacErlean, N. F. Couse, D. Campbell, K. McBride, D. MacErlean, J. J. Murphy, K. Kaar, H. Docrat, S. Malik, J. Egan, I. R. Davidson, J. Hurley, and H. Rowley
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Artificial urinary sphincter ,medicine.medical_specialty ,Fifteenth ,Chronic venous insufficiency ,business.industry ,Intestinal failure ,General surgery ,medicine ,General Medicine ,medicine.disease ,business ,Laparoscopic cholecystectomy - Published
- 1991
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31. Royal Academy of Medicine in Ireland section of biological sciences Proceedings of Summer Meeting held at University of Ulster at Jordanstown, 22nd & 23rd June, 1990
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J. M. Allen, A. A. Abu Shanab, D. J. S. Guthrie, G. B. Irvine, B. Walker, H. E. Bristow, J. J. Strain, R. W. Welch, T. P. Crotty, R. P. Kernan, J. B. Kearns, W. J. Hall, D. P. Cornell, D. P. O’Connell, A. C. B. Hooper, J. Doyle, P. O’Mahony, P. Murray, M. F. Farmer, M. J. Cresswell, J. Pórszász, J. F. Andrews, M. Kelly, B. Donne, A. Kelly, M. Szekely, L. A. Norris, M. E. Carroll, J. Bonnar, S. C. Sharma, B. L. Sheppard, K. A. Thompson, R. A. Shephard, M. A. Doran, A. Faulkner, L. R. Macartney, M. Keenan, T. D. Shields, B. M. Hannigan, S. J. Eason, W. S. Gillmore, G. D. Baxter, A. J. Bell, J. Ravey, C. C. McLoughlin, R. K. Mirakhur, E. R. Trimble, G. J. McCarthy, R. S. J. Carke, G. McCarthy, P. Elliott, M. S. McKinney, R. S. J. Clarke, J. W. Dundee, J. Yang, C. McMillan, K. F. McGeeney, D. Kelly, J. M. Fitzpatrick, N. McGuinness, R. Anwyl, T. C. Lee, E. B. Horner, J. P. Phillips, M. O’Brien, G. M. Lennon, P. C. Ryan, T. F. Gorey, A. D. K. Hill, J. Folan-Curran, S. A. Richardson, P. G. McKenna, E. Cromie, S. Ranjbar, A. Briscoe, K. L. O’Neill, G. W. Tully, O. Grant, J. G. Daly, C. J. Russell, A. Stewart, J. D. Allen, A. A. Jennifer Adgey, P. Nolan, D. McKeogh, A. Bradford, R. G. O’Regan, P. Nicholson, S. Gaynor, C. Boyle, B. L. Shepard, N. Gleeson, M. Cahill, E. Murphy, P. D. McDonagh, M. White, D. Phelan, N. Murphy, P. McDonagh, J. Billet, W. P. Blunnie, K. Pettersson, N. E. Wilson, T. F. Meert, Tayech Wubetu, C. Meban, E. McGlone, I. Halliday, P. Blair, B. J. Rowlands, K. E. M. Bailie, J. M. Bridges, Y. A. Wilkinson, C. C. M. Thompson, F. M. Amara, P. E. Ward, G. W. Moore, M. B. E. Livingstone, D. I. Thumham, G. B. Nevin, V. J. McKelvey, H. Monteverde, H. Logan, W. P. Abram, C. P. Nolan, S. J. Sheehan, M. K. Heatley, C. Whiteside, P. Maxwell, P. C. H. Watt, J. White, C. Whitside, Yvonne O’Shea, and Adrian Dunne
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business.industry ,Section (typography) ,Library science ,Medicine ,General Medicine ,business ,Biological sciences - Published
- 1991
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32. Irish society of gastroenterology
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E. J. Fitzgerald, A. Chua, C. Clabby, P. W. N. Keeling, J. M. Gilvarry, F. Keeling, O. Fitzgerald, J. F. Fielding, Elizabeth Mathai, T. O’Riordan, A. Tobin, S. Beattie, M. Cafferkey, C. T. Keane, C. O’Morain, P. J. O’Dwyer, A. Hassan, J. J. Murphy, N. J. Higgins, D. Kelly, G. P. McEntee, K. F. McGeeney, J. M. Fitzpatrick, D. P. Halpin, P. M. O’Byme, G. McEntee, T. P. Hermessy, R. B. Stephens, J. P. Hurley, P. Keeling, S. O’Brien, M. Keoghan, N. Afdhal, J. E. Hegarty, P. Burke, M. Sharp, O. Traynor, R. G. Molloy, M. G. O’Riordan, P. Gillen, W. O. Kirwan, E. Mathai, T. Keane, P. T. Byrne, R. Stuart, P. Lawlor, G. O’Sullivan, T. P. J. Hennessy, J. Hourihane, R. Stephens, F. J. Mullan, G. R. Campbell, J. Rowlands, S. T. D. McKelvey, F. I. Mullan, H. K. Wilson, W. Majury, J. Mills, A. J. Cromie, M. J. Kerin, D. O’Farrell, R. P. Waldron, J. G. Johnson, K. C. Trimble, D. P. Nunes, M. G. Courtney, L. Pomeroy, A. G. Shattock, F. M. Mulcahy, D. G. Weir, S. Ah-Kion, N. Noonan, J. Murphy, J. McNulty, M. Casey, M. X. Fitzgerald, B. Waldon, P. T. Cullen, D. Hopwood, D. Sutton, N. Kennedy, F. C. Campbell, N. MacMahon, B. Hogan, J. Murray, J. S. Doyle, J. M. Deasy, J. Carr, C. Bouchier-Hayes, A. P. Cleary, T. N. Walsh, W. F. Gawley, P. M. O’Byrne, M. I. Gleeson, D. T. Calthorpe, B. E. Lane, S. J. Heffernan, H. Sanfey, J. Steer, D. Cottell, M. Steer, T. F. Gorey, N. Nolan, P. Byme, R. Stewart, E. Nolan, E. Jones, M. MacMahon, P. Brennan, E. Carmody, D. Nizar, H. Osbome, R. L. O’Dwyer, F. Stevens, F. McCarthy, A. P. Clery, D. Bouchier-Hayes, S. Crerand, T. M. Feeley, R. Waldron, T. Corrigan, W. Hederman, and F. O’Cormell
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endocrine system ,medicine.medical_specialty ,endocrine system diseases ,business.industry ,Thyroid ,General Medicine ,Dapsone ,medicine.disease ,Asymptomatic ,Gastroenterology ,Anti-thyroid autoantibodies ,Coeliac disease ,medicine.anatomical_structure ,Internal medicine ,Dermatitis herpetiformis ,medicine ,Gluten free ,Thyroid function ,medicine.symptom ,business ,medicine.drug - Abstract
Abnormalities of the thyroid gland are said to be common in patients with dermatitis herpetiformis (DH), treated with dapsone (Thyroid abnormalities in dermatitis herpetiformis. Cunningham andZone, Annals Int.Med. 1985: 102, 194-196). Thepossibility that the goitrogenic effects of dapsone may play a role in this has not been evaluated. We therefore studied thyroid abnormalities in 40 patients with DH, 25 of whom were taking dapsone and 15 of whom were on a gluten free diet alone. All patients were examined clinically for evidence of thyroid dysfunction and blood was drawn for total thyroxine, thyrotrophin levels and thyroid microsomal antibdy titres. Six (24%) of dapsone treated patients had thyroid abnormalities, compared to 1 (7%) of the 15 patients treated with diet alone. Two patients became thyrotoxic when on treatment with dapsone. One patient had myxoedema prior to diagnosis of DH and one developed myxoedema while on dapsone. Two patients with asymptomatic goitres at the time of screening were taking dapsone and one patient on dapsone had thyroid antibodies. Thus it seems likely that the increased incidence of thyroid abnormalities in DH may be related to the effects of the sulphonamide on thyroid function.
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- 1991
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33. Time-varying pulmonary arterial compliance
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Brydon J. B. Grant, Baruch B. Lieber, and J. M. Fitzpatrick
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Physiology ,medicine.medical_treatment ,Pulmonary Artery ,Positive-Pressure Respiration ,chemistry.chemical_compound ,Dogs ,Physiology (medical) ,medicine.artery ,medicine ,Animals ,Lung volumes ,Expiration ,Positive end-expiratory pressure ,Meclofenamic Acid ,Chloralose ,business.industry ,Hemodynamics ,Vagus Nerve ,respiratory system ,Vagotomy ,Compliance (physiology) ,chemistry ,Anesthesia ,Pulmonary artery ,Circulatory system ,Respiratory Mechanics ,Vascular Resistance ,Lung Volume Measurements ,business - Abstract
We tested the hypothesis that pulmonary arterial compliance (Ca) varies during the ventilatory cycle. Pressure and flow in the main pulmonary artery were measured in open-chest dogs under chloralose anesthesia (n = 12) with a positive-pressure volume-cycled ventilator. Input impedance was calculated from the pressure and flow waves of heart cycles obtained immediately after the start of inspiration (SI) and immediately after the start of expiration (SE). A lumped parameter model was used to calculate Ca from the input impedance spectrum of the main pulmonary artery. Three levels of positive end-expiratory pressure (PEEP) were used before and after meclofenamate (n = 6) or vagotomy (n = 6). Ca was significantly greater at SE than at SI at each level of PEEP. PEEP increased Ca at SE but not at SI. None of these changes was altered by meclofenamate or vagotomy, suggesting that these differences of Ca were due to passive mechanical effects rather than an active neurohumoral mechanisms. We conclude that Ca is time varying during the ventilatory cycle because it is altered by the dynamic increase of lung volume between SI and SE, but not with the quasi-static increase of lung volume induced by raising the level of PEEP. These changes of Ca were unaffected by vagal feedback or inhibition of cyclooxygenase. We suggest that the increased Ca just after the start of expiration may result from dynamic shifts of blood volume from the extra-alveolar to the alveolar vessels.
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- 1991
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34. Millin Retropubic Prostatectomy
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J. M. Fitzpatrick
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- 2008
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35. Royal academy of medicine in ireland section of biological sciences
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Fiona M. Fleming, R. Jaggi, Salem Bazara, Alice Grogan, Eilis Carroll, Ann O’Mahony, Maura Grealy, Audrey McCormick, G. P. McEntee, L. Daly, N. G. McHale, John Bonnar, Bernadette Hennelly, M. Elliott, M. Touray, J. M. Fitzpatrick, A. C. B. Hooper, S. C. Sharma, A. Mcllgorm, Elinor R. Arbuthnott, K. F. McGeeney, Gwen Hughes, L. O’Brien, J. M. O’Donnell, Clare O'Connor, J. Feely, J. Kelly, Marie Jordan, F. Ryan, Mairead Stack, C. Power, J. C. McCarthy, K. D. Thornbury, J. F. Andrews, D. Rice, K. D. Thombury, John W. Dundee, Ann M. Murray, Catherine Wall, Muireann Brennan, M. S. H. Law, Muiris X. Fitzgerald, M. S. McKinney, A. K. Keenan, J. G. McGeown, B. Mitchell, Eithne Bolger, L. Clancy, A. B. Etwebi, Elinor Arbuthnott, D. Kelly, A. O’Brien, Clare Brenner, K. Mulpeter, G. S. A McDonald, Finian Martin, Alison L. Knaggs, J. Yang, B. L. Sheppard, Sandra Kehoe, B. Manning, T. G. Brien, Helen Harty, C. H. Homer, A. Crockard, M. D. O’Donnell, B. E. Leonard, F. R. Comerford, K. Ward, J. M. Allen, S. Saurer, and Roslynn Hall
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Veterinary medicine ,business.industry ,Section (typography) ,Medicine ,General Medicine ,business ,Biological sciences - Published
- 1990
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36. Should patients with symptomatic BPH have a trial of medical therapy by their general practitioner prior to referral for urological assessment?
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B B, McGuire, M F, O'Brien, S, McLoughlin, K J, O'Malley, and J M, Fitzpatrick
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Aged, 80 and over ,Male ,Prostatic Hyperplasia ,Urination ,Middle Aged ,Urination Disorders ,Practice Guidelines as Topic ,Prevalence ,Humans ,Prospective Studies ,Family Practice ,Referral and Consultation ,Adrenergic alpha-Antagonists ,Algorithms ,Aged - Abstract
The British Association of Urological Surgeons (BAUS) has recently recommended guidelines for the management of Lower Urinary Tract Sypmtoms by GPs outlining the indications for urological referral. We wished to assess the prescription of medical therapy by GPs in the referrals to our LUTS pre-assessment clinic. 115 consecutive patients were reviewed prospectively, over a three month period. Each patient was assessed for International Prostatic Symptom Score (IPSS) and Bother Score, uroflowometry with post void residual and whether medical therapy had been commenced (D-Blocker or 5-D-Reductase inhibitor). The majority of patients (75%) were classified with moderate symptoms. Only 10% of those with moderate symptoms and 5% of those with severe symptoms were commenced on medical therapy by their GP as recommended by the BAUS guidelines. Only 30 patients (26%) had completed an IPSS form with their GP. The majority of patients referred to our service for assessment of LUTS have at least moderate symptom severity and are not prescribed medical therapy by their GP. Further primary care education with greater emphasis on the BAUS LUTS algorithm prior to referral to an urologist should be encouraged.
- Published
- 2007
37. 'Urology: Today's Advances, Tomorrow's Clinical Practice', Cannes, November 2003. Current thinking in prostatic diseases: insights into dual 5alpha-reductase inhibitor therapy in BPH and prostate cancer
- Author
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J M Fitzpatrick
- Subjects
Gynecology ,Oncology ,Male ,Cancer Research ,medicine.medical_specialty ,business.industry ,Urology ,5alpha-reductase ,Prostatic Hyperplasia ,Prostatic Neoplasms ,Prostatic Diseases ,medicine.disease ,Chemoprevention ,Clinical Practice ,Prostate cancer ,Internal medicine ,medicine ,Humans ,business ,Randomized Controlled Trials as Topic - Published
- 2004
38. The importance of benign urological disease in communities
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P, Boyle and J M, Fitzpatrick
- Subjects
Adult ,Male ,Urologic Diseases ,Aging ,Korea ,Incidence ,Age Factors ,Middle Aged ,Europe ,Risk Factors ,Humans ,Multicenter Studies as Topic ,Female ,Aged - Published
- 2003
39. Chemoprevention for prostate cancer: the Prostate Cancer Prevention Trial
- Author
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J M, Fitzpatrick
- Subjects
Male ,Clinical Trials as Topic ,Risk Factors ,Finasteride ,Prostatic Hyperplasia ,Humans ,Prostatic Neoplasms ,Antineoplastic Agents ,Enzyme Inhibitors - Published
- 2003
40. Apoptosis in the prostate
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J M, Fitzpatrick and R W G, Watson
- Subjects
Male ,Androgens ,Prostate ,Humans ,Apoptosis - Abstract
The prostate requires androgens for development and glandular maintenance, dying by the process of apoptosis following their removal. Anti-androgen therapy is targeted to induce this process but eventually fails with the emergence of an androgen independent cancer. These cells have development mechanisms to survive with out androgen impart due to the expression of anti-apoptotic factors.
- Published
- 2003
41. Chemoprevention for prostate cancer - the way forward?
- Author
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J M, Fitzpatrick
- Subjects
Male ,Finasteride ,Humans ,Prostatic Neoplasms ,Antineoplastic Agents ,Chemoprevention - Published
- 2003
42. Laparoscopic reversal of Hartmann's procedure: Advantages and limitations
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J. M. Fitzpatrick, T. F. Gorey, M. A. Stokes, T.A. Carroll, and M. C. Regan
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Splenic flexure ,medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Fistula ,General surgery ,medicine.medical_treatment ,medicine.disease ,Surgery ,Rectal stump ,Laparotomy ,medicine ,Diverticular disease ,Hartmann's procedure ,Radiology, Nuclear Medicine and imaging ,Major complication ,Laparoscopy ,business - Abstract
SummaryHartmann's procedure has a role in emergency left colon surgery, and laparoscopic reversal may offer some advantages. We report the first 10 patients treated with attempted laparoscopic reversal according to our previously published technique. This was successful in five patients. Neither age, weight, mobilization of splenic flexure or interval to re-operation predicted successful laparoscopic re-anastomosis. One major complication, a recto-vesical fistula, occurred after conversion due to failure to dissect the rectal stump and required re-operation. We recommend attempted laparoscopic re-anastomosis in all cases, with early reconversion to laparotomy if the colo-stomy or rectal stump cannot be mobilized satisfactorily.
- Published
- 1994
- Full Text
- View/download PDF
43. A study of the anisotropically weighted procrustes problem [optical image-guided surgery application]
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P. Batchelor and J. M. Fitzpatrick
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Optical image ,medicine.medical_specialty ,Order (ring theory) ,Centroid ,Image registration ,Video camera ,Surgery ,law.invention ,Transformation (function) ,law ,medicine ,Symmetry (geometry) ,Orthogonal Procrustes problem ,Mathematics - Abstract
The authors studied the problem of finding an optimal rigid-body transformation that maps one configuration of points to a corresponding configuration when the alignment errors are anisotropically weighted. Such a problem arises in point-to-point registration, in particular when an optical device (e.g. microscope or video camera) is involved, as in image-guided surgery. The authors review the existing literature and algorithms and study the mathematical difficulties. After stating a symmetry condition for critical points, they use it to establish some results. In particular, they show that the starting configuration and weight matrices can have a special form (orthogonal columns), they show that the rotational part can be computed from configurations translated so that their centroids lie at the origin, and they give an estimate for the total number of critical points. The authors then compare the 2 existing algorithms, studying carefully their dependence on the different parameters, and propose an independent technique in order to validate them. This technique reduces the problem to the problem of finding the roots of a system of 3 polynomials in 3 variables.
- Published
- 2002
- Full Text
- View/download PDF
44. Intervertebral discs which cause low back pain secrete high levels of proinflammatory mediators
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J G, Burke, R W G, Watson, D, McCormack, F E, Dowling, M G, Walsh, and J M, Fitzpatrick
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Adult ,Male ,Sciatica ,Interleukin-6 ,Tumor Necrosis Factor-alpha ,Interleukin-8 ,Humans ,Female ,Inflammation Mediators ,Intervertebral Disc ,Intervertebral Disc Displacement ,Diskectomy ,Interleukin-1 - Abstract
Herniated intervertebral disc tissue has been shown to produce a number of proinflammatory mediators and cytokines, but there have been no similar studies using discs from patients with discogenic low back pain. We have compared the levels of production of interleukin-6 (IL-6), interleukin-8 (IL-8) and prostaglandin E2 (PGE2) in disc tissue from patients undergoing discectomy for sciatica (63) with that from patients undergoing fusion for discogenic low back pain (20) using an enzyme-linked immunoabsorbent assay. There was a statistically significant difference between levels of production of IL-6 and IL-8 in the sciatica and low back pain groups (p0.006 and p0.003, respectively). The high levels of proinflammatory mediator found in disc tissue from patients undergoing fusion suggest that production of proinflammatory mediators within the nucleus pulposus may be a major factor in the genesis of a painful lumbar disc.
- Published
- 2002
45. The loss of IAP expression during HL-60 cell differentiation is caspase-independent
- Author
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B T, Doyle, A J, O'Neill, P, Newsholme, J M, Fitzpatrick, and R W G, Watson
- Subjects
Enzyme Activation ,Caspases ,Protein Biosynthesis ,Humans ,Proteins ,Apoptosis ,Cell Differentiation ,HL-60 Cells ,Nerve Tissue Proteins ,X-Linked Inhibitor of Apoptosis Protein ,Neuronal Apoptosis-Inhibitory Protein ,Inhibitor of Apoptosis Proteins - Abstract
Human promyelocytic leukaemia cells (HL-60) differentiate into neutrophil-like cells that die spontaneously by apoptosis when treated with retinoic acid (RA). Inhibitors of apoptosis proteins (IAP) bind to and inhibit caspases 3, 7, and 9 activity and the induction of apoptosis. In this study, we demonstrate that undifferentiated HL-60 cells express IAP. During their differentiation, IAP expression is decreased at the mRNA and protein levels. In addition, we show that there is a corresponding increase in the expression and functional activity of active caspases 3 and 9. This activity was associated with the cleavage of XIAP, NAIP, and cIAP-2. Most importantly, we demonstrate that blocking caspase activity does not alter the decrease in IAP protein expression during differentiation but prevents caspase activation, IAP cleavage, and the induction of apoptosis. This result shows that the loss of IAP expression is independent of the induction of apoptosis and is solely related to the differentiation process. However, IAP cleavage is caspase-dependent. Terminal differentiation results in an altered apoptotic phenotype that is associated with the induction of HL-60 cell apoptosis.
- Published
- 2002
46. White paper: validation of medical image processing in image-guided therapy
- Author
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J. M. Fitzpatrick, R. Shahidi, David J. Hawkes, Michael W. Vannier, Pierre Jannin, Xavier Pennec, Vision, Action et Gestion d'informations en Santé (VisAGeS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Inria Rennes – Bretagne Atlantique, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-SIGNAUX ET IMAGES NUMÉRIQUES, ROBOTIQUE (IRISA-D5), Institut de Recherche en Informatique et Systèmes Aléatoires (IRISA), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université de Bretagne Sud (UBS)-École normale supérieure - Rennes (ENS Rennes)-Institut National de Recherche en Informatique et en Automatique (Inria)-Télécom Bretagne-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université de Bretagne Sud (UBS)-École normale supérieure - Rennes (ENS Rennes)-Institut National de Recherche en Informatique et en Automatique (Inria)-Télécom Bretagne-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche en Informatique et Systèmes Aléatoires (IRISA), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université de Bretagne Sud (UBS)-École normale supérieure - Rennes (ENS Rennes)-Télécom Bretagne-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), Vanderbilt University [Nashville], Computational Imaging Science Group [London], King‘s College London, Medical imaging and robotics (EPIDAURE), Inria Sophia Antipolis - Méditerranée (CRISAM), Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria), Stanford University, University of Iowa [Iowa City], Lemke, H.U. and Vannier, M.W. and Inamura, K. and Farman, A.G. and Doi, K. and Reiber, J.H.C., Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-Université de Bretagne Sud (UBS)-École normale supérieure - Rennes (ENS Rennes)-Institut National de Recherche en Informatique et en Automatique (Inria)-Télécom Bretagne-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-Université de Rennes 1 (UR1), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-Université de Bretagne Sud (UBS)-École normale supérieure - Rennes (ENS Rennes)-Institut National de Recherche en Informatique et en Automatique (Inria)-Télécom Bretagne-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche en Informatique et Systèmes Aléatoires (IRISA), and Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-Université de Bretagne Sud (UBS)-École normale supérieure - Rennes (ENS Rennes)-Télécom Bretagne-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)
- Subjects
Image-Guided Therapy ,Process (engineering) ,Computer science ,[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging ,Image registration ,Image processing ,030230 surgery ,Machine learning ,computer.software_genre ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,[INFO.INFO-TS]Computer Science [cs]/Signal and Image Processing ,[INFO.INFO-IM]Computer Science [cs]/Medical Imaging ,Computer vision ,Segmentation ,ComputingMilieux_MISCELLANEOUS ,Ground truth ,business.industry ,[INFO.INFO-MO]Computer Science [cs]/Modeling and Simulation ,3. Good health ,Visualization ,Key (cryptography) ,Artificial intelligence ,business ,computer ,[SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing - Abstract
Clinical use of image-guided therapy (IGT) systems has grown, creating the need for a common and rigorous validation methodology, as reported in recent workshops and conferences. [1,2,3,4] One key characteristic of IGT systems is that they employ medical image processing methods (e.g. segmentation, registration, visualization, calibration). As a result of this intrinsic structure, validation of IGT systems should include both individual validation of these components, validation of the overall system and a study of how uncertainties propagate through the entire image guided therapy process. Significant progress has been made on IGT system validation recently. Today almost all peer-reviewed publications reporting on the development of new medical image processing methods include a validation section, but this was not always true in the past.
- Published
- 2002
- Full Text
- View/download PDF
47. Priming prostate carcinoma cells for increased apoptosis is associated with up-regulation of the caspases
- Author
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R N, Coffey, R W, Watson, P K, Hegarty, C L, Watson, L, Wolohan, H R, Brady, C, O'Keane, and J M, Fitzpatrick
- Subjects
Intracellular Fluid ,Male ,Radiotherapy ,Blotting, Western ,Carcinoma ,Maleates ,Prostatic Neoplasms ,Apoptosis ,Antineoplastic Agents, Phytogenic ,Glutathione ,Genes, bcl-2 ,Up-Regulation ,Caspases ,Tumor Cells, Cultured ,Humans ,Immunotherapy ,Sulfhydryl Compounds ,Etoposide - Abstract
The potential to prime prostatic carcinoma cell lines for apoptosis represents an exciting strategy for the treatment of patients with this disease. The ability and the underlying molecular mechanisms involved in sensitizing both androgen-sensitive and androgen-insensitive cell types to a range of apoptotic-inducing agents are investigated by the authors.Primary and secondary cell lines were pretreated with diethyl-maleate (DEM) prior to the induction of apoptosis by Fas antibody (1 microg/mL), cycloheximide (1 microg/mL), etoposide (62.5 microM), and radiation (5 grays). It was demonstrated previously that DEM (50 microM) increases the sensitivity to apoptosis induced by these agents. The effects of DEM on both protein and RNA expression was determined by Western blot analysis and a ribonuclease protection assay, respectively. The effects of DEM on intracellular glutathione (GSH) levels and its intracellular distribution also were assessed.DEM did not affect the expression of the caspases at the transcriptional level but was associated with increased procaspase-3 and caspase-8 protein levels. DEM preincubation restored sensitivity to Fas antibody and radiation-induced apoptosis in cells from the LNCaP-bcl-2 transfectant cell line that, normally, are resistant to these apoptotic stimuli. It is that DEM chemically depletes intracellular thiol levels. Although no depletion in total intracellular thiol GSH was observed at these concentrations of DEM, trafficking of GSH from the nucleus to the cytosol was demonstrated.Identification of the caspases as a potential target for chemical manipulation may serve as an effective, adjuvant-based approach in the treatment of patients with prostate carcinoma and, in particular, for immunotherapy and radiation-based strategies that rely on the activation of these death-effector proteases.
- Published
- 2001
48. An autoradiographic study of regional blood flow distribution in the rat kidney during ureteric obstruction--the role of vasoactive compounds
- Author
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P, Sweeney, L S, Young, and J M, Fitzpatrick
- Subjects
Male ,Diclofenac ,Anti-Inflammatory Agents, Non-Steroidal ,Thromboxanes ,Kidney ,Rats ,Rats, Sprague-Dawley ,Renin-Angiotensin System ,Regional Blood Flow ,Vasoconstriction ,Prostaglandins ,Animals ,Autoradiography ,Antipyrine ,Ureteral Obstruction - Abstract
To determine the changes in regional renal blood flow during ureteric obstruction and to examine the role of vasoactive mediators in effecting these changes.Renal blood flow in Sprague-Dawley rats was assessed after periods of ureteric obstruction using a quantitative autoradiographic technique based on Kety's theory of diffusion of an inert tracer (14C-iodoantipyrine). Prostaglandins, thromboxanes and renin-angiotensin were inhibited pharmacologically using diclofenac sodium and enalapril.Baseline blood flow to the outer cortex, inner cortex and medulla was 807, 258 and 105 mL/100 g/min, respectively. There was an increase in outer cortical blood flow after 10 min of ureteric obstruction which became significant at 30 min (P0.05). There was a significant decrease in inner cortical and medullary blood flow at 30 min, to 210 and 68 mL/100 g/min, respectively (P0.05). Diclofenac sodium abolished the increase in outer cortical blood flow. After 24 h of unilateral ureteric obstruction, outer cortical blood flow decreased to 492 mL/100 g/min; inner cortical blood flow also decreased but to a lesser extent, to 190 mL/100 g/min. Inhibition of prostaglandins, thromboxanes and the renin-angiotensin system reduced the degree of renal vasoconstriction but there was still a significant decrease in outer cortical perfusion despite the presence of these blocking agents.The control of the renal vasculature involves a complex interplay between a variety of vasoactive mediators. Quantitative autoradiography offers the opportunity to evaluate changes in regional renal perfusion with high resolution and will allow a greater understanding of the pathophysiology of renal diseases.
- Published
- 2001
49. Migration of a prosthetic acetabulum into the bladder
- Author
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A W, O'Sullivan, K J, O'Malley, J M, Fitzpatrick, and J S, Smith
- Subjects
Foreign-Body Migration ,Arthroplasty, Replacement, Hip ,Urinary Bladder ,Humans ,Acetabulum ,Female ,Hip Prosthesis ,Aged - Published
- 2001
50. Selected abstracts
- Author
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P. P. Corkery, B. F. Leek, B. Caulfield, M. Garrett, J. P. Gormley, P. M. O’Donnell, N. Kennedy, K. Sayers, E. Stokes, B. Bresnihan, O. Fitzgerald, M. A. McGarvey, M. Tonra, A. C. B. Hooper, J. Barry, B. Maurer, J. Hussey, J. Gormley, J. G. Noble, J. Alves-Guerreiro, A. S. Lowe, D. M. Walsh, B. NicNiocaill, M. Harte, W. T. O’Connor, A. M. O’Hara, A. Orren, A. P. Moran, D. A. Hardiman, T. C. Lee, D. T. Croke, R. Tolan, S. McBennett, S. Warmington, M. McGuire, A. Bradford, T. O’Hare, M. MacDermott, F. Lynch, R. G. O’Regan, P. McLoughlin, T. Quinn, J. P. Ryan, M. Pickering, D. P. Campion, J. F. X. Jones, S. Ryan, W. T. McNicholas, P. Nolan, F. J. Doyle, S. M. Rackard, P. Beddy, V. A. Campbell, Y. S. Bakhle, C. Bell, C. Usher, L. Chan, A. K. Keenan, K. E. McQuaid, V. C. Cullen, E. M. Smith, A. Kelly, M. A. Lynch, D. B. Freir, C. Holscher, C. E. Herron, H. A. Pearson, B. P. Curran, J. J. O’Connor, A. Quinn, J. McHale, D. Moriarty, J. O’Connor, J. C. Glennon, B. J. Van Vliet, S. K. Long, C. Kruse, H. C. Gallagher, C. L. Bacon, B. Boland, A. M. Griffin, J. Preisler, L. O’Brien, C. M. Regan, S. Hurley, P. J. Kearney, J. Slevin, C. Barry-Kinsella, C. A. Ryan, O. Kllleen, J. Glllan, T. Clarke, T. Matthews, D. Corcoran, E. Dunn, M. Geary, C. O’Herlihy, D. Keane, M. M. Slattery, M. J. O’Leary, J. J. Morrison, E. Ryan, W. A. Gorman, A. Bourke, J. Larkin, C. Mayes, J. Jenkins, M. Ryan, S. Lalchandani, O. Sheil, N. Lynch, C. Costigan, J. F. Murphy, R. Bhatia, A. Foran, V. Donohue, P. McParland, P. LaSjaunais, G. Rodesch, M. McGinn, J. McAloon, M. O’Leary, K. Astbury, D. Harmon, A. Sharkey, G. Gaffney, G. O’Regan, C. McMahon, D. Murray, C. McDermott, E. Woolhead, J. Gillan, J. L. Cartmill, M. A. Harper, N. Al-Shabibi, M. Hanahoe, M. Wingfield, J. A. M. Larkin, A. H. Bell, B. G. McClure, L. Sweeney, D. H. Martin, P. O’Donoghue, A. Davoren, G. F. Lucas, J. McKiernan, D. M. T. Gallagher, K. P. Dunne, O. Fulena, M. Sheridan, E. Griffin, M. White, P. Deasy, M. O’Riordan, C. O’Gorman, C. Mongan, M. McCafferkey, G. Henry, P. McKenna, A. O’Malley, D. Devaney, P. Kelleghan, E. E. Mooney, J. E. Gillan, M. Fitzpatrick, K. McQuillan, C. Heffron, P. Hodnett, A. Curtain, T. C. F. O’Connor, T. G. Connell, D. Waldron, W. Gorman, T. Bolger, M. O’Keefe, J. Murphy, L. M. Dolan, A. I. Traub, A. E. Curley, H. L. Halliday, T. R. J. Tubman, O. Kileen, H. Riadha, J. Russell, R. Philips, C. Regan, I. Ali, A. C. J. Coughlan, M. J. Turner, A. Smith, D. O’Flanagan, D. Igoe, F. Ryan, D. Forde, E. McArdle, D. Ko, D. Bedford, M. Hegarty, B. Dunlevy, R. Corcoran, T. Holohan, A. Feeney, H. McGee, W. Shannon, M. Condon, C. Hyland, G. Sayers, E. Feely, D. Crowley, D. O’Reilly, T. O’Connell, M. Cronin, H. Johnson, M. Fitzgeraldi, M. Cafferkey, A. Breslin, C. J. Bonner, B. Foley, M. Fitzgerald, P. G. Wall, E. McNamara, P. Costigan, T. Prendergast, K. Foye, C. Cosgrove, A. Keane, E. Murphy, J. O’Donnell, A. Quinlan, L. Thornton, E. A. Roch, R. A. Lyons, A. Maddocks, P. Barnes, L. Price, M. McCabe, P. Nash, A. Midha, Y. Doyle, A. Kilgallen, P. Wright, T. Ryan, D. De La Harpe, V. Harkins, C. Brennan, V. O’Connell, D. S. Evans, J. Ni Mhuircheartaigh, J. M. O’Donnell, A. Rhatigan, E. Shelley, C. Collins, M. Byrne, A. W. Murphy, P. K. Plunkett, A. Murray, G. Bury, F. Lynam, G. McMahon, T. Greally, D. Kane, D. Veale, R. Reece, S. Busteed, M. W. Bennett, M. Stone, C. Molloy, J. O’Connell, M. G. Molloy, F. Shanahan, J. Guerin, E. Casey, C. Feighery, F. Lin, J. Jackson, A. Pendleton, G. D. Wright, A. E. Hughes, D. O’Gradaigh, I. Debham, J. Compston, A. McEvoy, E. P. Murphy, D. Salonen, P. Payne, M. Lax, V. Lapp, R. Inman, K. O’Rourke, D. Brennan, J. Harty, C. McCarthy, J. O’Byrne, S. Eustace, H. Chirayath, N. W. Liggett, M. P. Morgan, D. J. Fitzgerald, C. J. McCarthy, G. M. McCarthy, R. Z. Lee, K. Wai, D. Nevin, A. O. Leary, R. Lee, E. B. Casey, A. O’Leary, D. Breen, D. Tuite, D. McInerney, R. Sim, A. L. Frederic, O. Smith, B. White, M. Murphy, C. Silke, E. O’Keeffe, N. Fanning, L. Spence, N. A. Parfrey, J. R. McConnell, A. D. Crockard, A. P. Cairns, A. L. Bell, O. Kavanagh, D. A. Moyes, M. Finch, M. Rooney, A. Bell, I. Founas, A. El-Magbri, S. Mooney, M. Kennedy, R. J. Coughlan, S. A. Ramakrishnan, A. Gsel, O. Finnerty, M. Burns, M. Yateman, C. Camaco-Hubner, C. F. Matthews, A. Taggart, K. Fuller, M. S. Murphy, M. Phelan, T. B. Murphy, F. Wynne, K. Quane, M. Daly, J. O’Leary, I. da Silva, N. Bermingham, M. Gogarty, L. P. Gallagher, R. O’Hara, C. Godson, H. Brady, H. Osman, A. El-Rafie, D. Foley-Nolan, P. Kirwan, O. Corcoran, T. Duffy, F. Drummond, A. Madigan, D. Williams, P. Gallagher, C. Hatton, S. Cunningham, O. FitzGerald, P. Minnock, E. Wylie, D. Egan, J. Mc Cormack, M. O. Shea, D. Evans, P. O’Lorcain, H. Comber, A. Evans, J. Jones, C. Garavan, K. Kelleher, M. C. Boland, R. Healy, M. B. O’Sullivan, M. Burke, P. Mc Donald, R. Smithson, J. Glass, C. A. Mason, N. Mullins, D. Nolan, P. McCormick, S. Coughlan, S. Dooley, C. C. Kelleher, A. Hope, F. Murphy, M. Barry, J. Sixsmith, A. MacFarlane, C. MacLeod, G. McElroy, D. O’Loan, F. Kennedy, R. M. Kerr, J. Lim, S. P. A. Allwright, F. L. Bradley, J. M. G. Barry, J. Long, J. V. Parry, D. Creagh, I. J. Perry, A. Collins, S. Neilson, N. Colwell, D. O’Halloran, S. O’Neill, S. McErlain, M. Okasha, B. Gaffney, P. McCarron, R. Hinchion, C. Drew, A. Gavin, D. Fitzpatrick, R. Campbell, S. G. Wannamethee, A. Shaper, S. Friel, C. Kelleher, F. Kee, C. C. Atterson, E. A. Wilson, J. M. McConnell, S. M. Wheeler, J. D. Watson, N. Norashikin Rahman, J. Sheehan, C. Wall, B. Kelleher, S. D. O’Broin, R. N. Mullan, P. J. McKeveney, V. M. Hodges, P. C. Winter, P. Maxwell, D. A. Simpson, T. R. J. Lappin, A. P. Maxwell, J. A. Eustace, J. Coresh, C. Kutchey, P. L. Te, L. F. Gimenez, P. J. Scheel, M. Walser, R. A. McMahon, M. Clarkson, F. Martin, H. R. Brady, C. Blake, Y. M. O’Meara, S. Gupta, H. MacKenzie, S. Doyle, T. Fotheringham, P. Haslam, M. P. Logan, P. Conlon, M. Lee, P. Maderna, D. C. Cottell, S. Mitchell, C. Gulmann, R. Østerby, H. J. Bangstad, S. Rljdberg, M. Dempsey, S. Nathwani, M. P. Ryan, B. McMahon, C. Stenson, H. Murtagh, J. H. Brown, P. Doran, A. McGinty, M. A. Little, E. O’Brien, P. Owens, J. Holian, F. Mee, J. J. Walshe, S. A. Omer, D. Power, P. Diamond, R. W. Watson, A. Shahsafei, T. Jiang, B. M. Brenner, H. S. Mackenzie, J. Neary, A. Dorman, M. Keoghan, E. Campbell, J. Walshe, M. Little, L. Nee, C. O’Ceallaigh, H. McGlynn, E. Bergin, P. J. Garrett, T. Keane, G. Gormley, A. Watson, M. G. Atta, T. M. Perl, X. Song, E. Healy, M. Leonard, J. Lynch, A. J. Watson, D. Lappin, D. W. P. Lappin, K. Hannan, M. Burne, F. Daniels, H. Rabb, B. McBride, N. Kieran, C. Shortt, M. Codd, F. Murray, A. McCormack, C. Brown, C. Wong, A. M. Dorman, M. Keogan, J. Donohue, J. Farrell, J. Donohoe, S. O’Broin, A. Balfe, G. J. Mellotte, K. A. Abraham, C. McGorrian, A. E. Wood, M. Neligan, B. D. Kelly, P. Finnegan, M. Cormican, J. Callaghan, J. K. G. Crean, T. A. Moffitt, H. L. Devlin, A. Soosay, D. O’Neill, A. Counihan, D. Hickey, M. T. Keogan, K. Harvey, E. O’Riordan, S. Waldek, P. A. Kalra, D. J. O’Donoghue, R. N. Foley, A. O’Riordan, D. Kelliher, G. Mellotte, L. Giblin, J. A. B. Keogh, M. O’Connell, A. O’Meara, F. Breatnach, J. Gillick, H. Tazawa, P. Puri, E. Molloy, A. J. O’Neill, M. Sheridan-Pereira, J. M. Fitzpatrick, D. W. Webb, R. W. G. Watson, B. Linnane, C. O’Donnell, T. A. Clarke, C. Martin, M. McKay, J. McBrien, F. Glynn, C. O’Donovan, W. W. Hall, J. Smith, K. Khair, R. Liesner, I. M. Hann, O. P. Smith, S. Gallagher, M. J. Mahony, A. Hilal, J. F. Cosgrove, C. Monaghan, B. Craig, A. Al-Hassan, K. Walsh, D. Duff, P. O. Slizlok, C. Halahakoon, C. MacPherson, S. McMillan, E. E. Dalzell, J. McCaughan, A. O. B. Redmond, D. DeCaluwe, A. Yoneda, U. Akl, E. Dempsey, M. Farrell, D. Webb, A. Elabbas, G. Fox, S. Gormally, B. Grant, C. W. B. Corkey, A. Nicholson, A. Murphy, P. O’Grady, O. Barry, C. Macpherson, M. C. Stewart, F. Alderdice, T. G. Matthews, M. McDonnell, C. McGarvey, M. O’Regan, M. Ní Chróinín, P. Tormey, S. Ennis, A. J. Green, S. Abbas, A. O’Marcaigh, M. Conran, E. Crushell, A. Saidi, P. Curran, V. Donoghue, M. D. King, B. Elnazir, J. Leonard, C. Kavanagh, D. Brown, N. Corrigan, B. McCord, M. Quinn, L. O’Connell, B. Mcdonagh, A. Awan, D. Gill, R. Kakkar, D. G. Sweet, J. A. Warner, C. O’Connor, M. Herzig, A. Twomey, M. J. White, B. Sweeney, R. Surana, A. Hodgson, M. Rafferty, W. Livingstone, D. Peake, E. Wassemer, W. Whitehouse, N. Abdullah, P. Oslizlok, N. O’Connell, J. Balding, W. J. Livingstone, M. Healy, L. Mynett-Johnson, I. McAllister, A. C. Dick, B. Herron, V. E. Boston, C. O. Callaghan, D. O. Brien, A. Walsh, M. Philip, D. McShane, M. C. V. Hoey, F. Sharif, M. McDermott, M. Dillon, B. Drumm, M. Rowland, C. Imrie, S. Kelleher, B. Bourke, M. Iqbal, Y. Ziedan, M. O’Neill, S. O’Riordan, S. M. B. Basheer, S. O’Callaghan, A. Chong, M. Kelly, A. J. Nicholson, R. Cooke, C. Sreenan, M. Fallon, B. Denham, V. Dowding, G. Cussen, V. McManus, O. Hensey, H. Monaghan, S. N. Basheer, E. Quinn, H. M. C. V. Hoey, S. Mohamed, R. R. Ramesh, P. Mayne, E. Tracy, S. M. Gormally, E. Curtis, N. McCallion, R. Watson, O. O’Mahony, M. Keegan, K. Ward, D. Barton, J. Poulton, E. Treacy, J. Honour, D. deCaluwe, M. Ni Chróinín, J. Cosgrove, T. S. Chaudhry, N. M. Long, B. Lynch, P. Lasjaunais, D. G. M. McDonald, J. B. McMenamin, M. J. Farrell, E. F. Roche, A. Menon, C. Buckley, A. Mackey, K. Ohlandieck, A. Das, D. Reilly, O. Killeen, J. Harper, E. Roche, H. Hoey, J. Caird, D. O’Brien, D. Allcutt, N. Farrington, J. F. A. Murphy, J. M. Savage, A. J. Sands, F. A. Casey, B. G. Craig, J. C. Dornan, J. Johnston, C. Patterson, C. Lynch, H. C. Mulholland, D. C. Watkins, I. Young, G. Cran, C. A. G. Boreham, W. A. McCallion, N. F. Clements, M. R. Stevenson, D. O’Donoghue, L. Jenkins, A. J. Thompson, M. D. Shields, R. T. Taylor, R. Kerr, J. L. Hughes, M. Stewart, P. Jackson, C. Fitzpatrick, M. Rasheed, E. Colhoun, A. G. Bailie, S. Gray, S. Brown, A. Curley, K. J. MacMahon, C. M. O’Connor, A. Nichelson, N. E. Lynch, D. Finch, M. Foley, E. Scallan, B. Dillon, S. Lyons, R. O’Loughlin, M. Ward, R. Nally, A. Harkin, J. P. Kelly, B. E. Leonard, B. Nic Niocaill, P. Magee, T. J. Connor, Y. Shen, G. R. McCullough, S. M. McDonough, A. F. L. Cramp, M. Hynes, P. Corkery, M. Carey, D. McGarrigle, S. Higgins, H. Murray, C. J. Moran, M. C. Dennedy, J. Brosnan, L. Morris, B. L. Sheppard, A. Black, B. Wilkins, J. Folan-Curran, K. Skelton, M. Owens, C. Nemeroff, D. Houlihan, C. O’Keeffe, N. Nolan, P. A. McCormick, A. W. Baird, I. Raducan, P. Corcoran, R. Brennan, P. Molloy, A. Friel, M. Maher, M. Glennon, T. Smith, A. Nolan, J. A. Houghton, O. Carroll, S. Colleran, G. O’Cuinn, H. M. Snow, D. O’Regan, H. F. Markos, K. Pollock, D. M. Cannon, G. McBean, L. R. Quinlan, M. T. Kane, B. D. Higglns, D. M. Moriarty, D. Fitzgerald, A. Katkada, G. Canny, P. MacMathuna, M. M. O’Donovan, A. G. Schuur, K. J. Murphy, A. G. Foley, S. J. M. ten Bruggencate, and L. Ireland
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General Medicine - Published
- 2000
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