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1. Design Space Exploration of K-Demo Using Novel Method for the Minimum Build Determination

Author: G. Jo, J. -M. Kwon, A. Cho, H. -K. Chung, and B. G. Hong
Subjects: Nuclear and High Energy Physics, Condensed Matter Physics
Published: 2022
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2. Progress in gyrokinetic validation studies using NBI heated L-mode discharge in KSTAR

Author: D. Kim, J. Kang, M.W. Lee, J. Candy, E.S. Yoon, S. Yi, J.-M. Kwon, Y.-c. Ghim, W. Choe, and C. Sung
Subjects: General Physics and Astronomy, General Materials Science
Published: 2022
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3. A new hybrid-Lagrangian numerical scheme for gyrokinetic simulation of tokamak edge plasma.

Author: Seung-Hoe Ku, Robert Hager, Choong-Seock Chang, J. M. Kwon, and Scott E. Parker
Published: 2016
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4. Deep learning-based electrocardiogram analysis detecting paroxysmal atrial fibrillation during sinus rhythm in patients with cryptogenic stroke: validation study using implantable cardiac monitoring

Author: K H Jeon, J M Kwon, M S Lee, Y J Cho, I Y Oh, and J H Lee
Subjects: General Engineering, General Earth and Planetary Sciences, Cardiology and Cardiovascular Medicine, General Environmental Science
Abstract: Background Atrial fibrillation (AF) is the most cause of cardioembolic source causing cryptogenic stroke. In these, anticoagulation therapy could reduce recurrence of stroke. However, paroxysmal AF would not be detected even by 24 hours Holter monitoring. Deep learning-based electrocardiogram (ECG) analysis models were recently developed to detect AF during sinus rhythm. Purpose We aimed to develop a deep learning algorithm (DLA) to detect AF during sinus rhythm and validate the model in patients with cryptogenic stroke who underwent implantable cardiac monitoring (ICM) to diagnose paroxysmal AF. Methods This cohort study involved three hospitals (A, B, and C). We developed a DLA to detect AF using sinus rhythm 10 s 12-lead ECG. We included adult patients aged ≥18 years from hospital A and B. We used development data from AF adult patients who had at least one atrial fibrillation rhythm in the study period (Jan 2016 to Dec 2021) and non-AF patients who had no reference to AF in the ECG and electronic medical record. DLA was based on convolutional neural network (CNN) using 10 s 12-lead. For external validation, the ECGs from 217 patients (hospital C) with cryptogenic stroke who underwent ICM were analyzed by using the DLA for validating the accuracy in the real-world clinical situations. Results We included 10,605 AF adult patients and 50,522 non-AF patients as development data. During the internal validation, the area under the curve (AUC) of the final DLA based on CNN was 0.793 (95% Confidence interval 0.778–0.807). In external validation data from cryptogenic stroke patients, the mean ICM duration was 15.1 months, and AF >5 mins was detected in 32 patients (14.5%). The diagnostic accuracy of DLA was 0.793 to detect AF during sinus rhythm, and AUC was 0.824. The sensitivity, specificity, positive predictive value, and negative predictive value of the model were 0.844, 0.784, 0.403, and 0.967, respectively, which outperformed other conventional predictive methods based on clinical factors, such as CHARGE-AF, C2hest, and HATCH. Conclusions In this study, DLA accurately detected paroxysmal AF using 12-leads normal sinus rhythm ECG in patients with cryptogenic stroke and outperformed the conventional models. The DLA could be used as a screening tool to identify the cause of stroke in the future. Funding Acknowledgement Type of funding sources: None.
Published: 2022
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5. Inclusive and differential cross section measurements of single top quark production in association with a Z boson in proton-proton collisions at root s=13 TeV

Author: Tumasyan, A. Adam, W. Andrejkovic, J. W. Bergauer, T. and Chatterjee, S. Damanakis, K. Dragicevic, M. Del Valle, A. Escalante Fruhwirth, R. Jeitler, M. Krammer, N. Lechner, L. Liko, D. Mikulec, I Paulitsch, P. Pitters, F. M. and Schieck, J. Schofbeck, R. Schwarz, D. Templ, S. and Waltenberger, W. Wulz, C-E Chekhovsky, V Litomin, A. and Makarenko, V Darwish, M. R. De Wolf, E. A. Janssen, T. and Kello, T. Lelek, A. Sfar, H. Rejeb Van Mechelen, P. Van Putte, S. Van Remortel, N. Blekman, F. Bols, E. S. and D'Hondt, J. Delcourt, M. El Faham, H. Lowette, S. and Moortgat, S. Morton, A. Muller, D. Sahasransu, A. R. and Tavernier, S. Van Doninck, W. Stylianou, N. Beghin, D. and Bilin, B. Clerbaux, B. De Lentdecker, G. Favart, L. and Grebenyuk, A. Kalsi, A. K. Lee, K. Mahdavikhorrami, M. and Makarenko, I Moureaux, L. Petre, L. Popov, A. Postiau, N. Starling, E. Thomas, L. Vanden Bemden, M. Vander Velde, C. Vanlaer, P. Gao, X. Cornelis, T. Dobur, D. and Knolle, J. Lambrecht, L. Mestdach, G. Niedziela, M. and Roskas, C. Samalan, A. Skovpen, K. Tytgat, M. Vermassen, B. Wezenbeek, L. Benecke, A. Bethani, A. Bruno, G. and Bury, F. Caputo, C. David, P. Delaere, C. Donertas, I. S. Giammanco, A. Jaffel, K. Jain, Sa Lemaitre, V and Mondal, K. Prisciandaro, J. Taliercio, A. Teklishyn, M. and Tran, T. T. Vischia, P. Wertz, S. Alves, G. A. Hensel, C. Moraes, A. Teles, P. Rebello Alda Junior, W. L. Gallo Pereira, M. Alves Ferreira Filho, M. Barroso Malbouisson, H. Brandao Carvalho, W. Chinellato, J. Da Costa, E. M. Da Silveira, G. G. Damiao, D. De Jesus De Souza, S. Fonseca and Herrera, C. Mora Amarilo, K. Mota Mundim, L. Nogima, H. and Santoro, A. Silva Do Amaral, S. M. Sznajder, A. Thiel, M. and De Araujo, F. Torres Da Silva Pereira, A. Vilela Bernardes, C. A. Calligaris, L. Tomei, T. R. Fernandez Perez Gregores, E. M. Lemos, D. S. Mercadante, P. G. Novaes, S. F. and Padula, Sandra S. Aleksandrov, A. Antchev, G. Hadjiiska, R. and Iaydjiev, P. Misheva, M. Rodozov, M. Shopova, M. and Sultanov, G. Dimitrov, A. Ivanov, T. Litov, L. Pavlov, B. Petkov, P. Petrov, A. Cheng, T. Javaid, T. and Mittal, M. Yuan, L. Ahmad, M. Bauer, G. Dozen, C. and Hu, Z. Martins, J. Wang, Y. Yi, K. Chapon, E. Chen, G. M. Chen, H. S. Chen, M. Iemmi, F. Kapoor, A. and Leggat, D. Liao, H. Liu, Z-A Milosevic, V Monti, F. and Sharma, R. Tao, J. Thomas-Wilsker, J. Wang, J. Zhang, H. and Zhao, J. Agapitos, A. An, Y. Ban, Y. Chen, C. and Levin, A. Li, Q. Lyu, X. Mao, Y. Qian, S. J. Wang, D. Xiao, J. Lu, M. You, Z. Okawa, H. Zhang, Y. and Zhang, L. Lin, Z. Xiao, M. Avila, C. Cabrera, A. and Florez, C. Fraga, J. Mejia Guisao, J. Ramirez, F. Ruiz Alvarez, J. D. Salazar Gonzalez, C. A. Giljanovic, D. and Godinovic, N. Lelas, D. Puljak, I Antunovic, Z. Kovac, M. Sculac, T. Brigljevic, V Ferencek, D. Majumder, D. and Roguljic, M. Starodumov, A. Susa, T. Attikis, A. and Christoforou, K. Erodotou, E. Ioannou, A. Kole, G. and Kolosova, M. Konstantinou, S. Mousa, J. Nicolaou, C. and Ptochos, F. Razis, P. A. Rykaczewski, H. Saka, H. and Finger, M. Finger Jr, M. Jr Kveton, A. Ayala, E. Carrera Jarrin, E. Abdalla, H. Assran, Y. Lotfy, A. Mahmoud, M. A. Bhowmik, S. Dewanjee, R. K. Ehataht, K. Kadastik, M. and Nandan, S. Nielsen, C. Pata, J. Raidal, M. Tani, L. and Veelken, C. Eerola, P. Forthomme, L. Kirschenmann, H. and Osterberg, K. Voutilainen, M. Bharthuar, S. Brucken, E. and Garcia, F. Havukainen, J. Kim, M. S. Kinnunen, R. and Lampen, T. Lassila-Perini, K. Lehti, S. Linden, T. and Lotti, M. Martikainen, L. Myllymaki, M. Ott, J. and Siikonen, H. Tuominen, E. Tuominiemi, J. Luukka, P. and Petrow, H. Tuuva, T. Amendola, C. Besancon, M. Couderc, F. Dejardin, M. Denegri, D. Faure, J. L. Ferri, F. and Ganjour, S. Gras, P. de Monchenault, G. Hamel Jarry, P. and Lenzi, B. Locci, E. Malcles, J. Rander, J. Rosowsky, A. and Sahin, M. O. Savoy-Navarro, A. Titov, M. Yu, G. B. and Mijuskovic, J. Ahuja, S. Beaudette, F. Bonanomi, M. and Perraguin, A. Buchot Busson, P. Cappati, A. Charlot, C. and Davignon, O. Diab, B. Falmagne, G. Ghosh, S. de Cassagnac, R. Granier Hakimi, A. Kucher, I Motta, J. and Nguyen, M. Ochando, C. Paganini, P. Rembser, J. Salerno, R. Sarkar, U. Sauvan, J. B. Sirois, Y. Tarabini, A. and Zabi, A. Zghiche, A. Agram, J-L Andrea, J. Apparu, D. and Bloch, D. Bourgatte, G. Brom, J-M Chabert, E. C. and Collard, C. Darej, D. Fontaine, J-C Goerlach, U. and Grimault, C. Le Bihan, A-C Nibigira, E. Van Hove, P. and Asilar, E. Beauceron, S. Bernet, C. Boudoul, G. Camen, C. Carle, A. Chanon, N. Contardo, D. Depasse, P. El Mamouni, H. Fay, J. Gascon, S. Gouzevitch, M. Ille, B. and Laktineh, I. B. Lattaud, H. Lesauvage, A. Lethuillier, M. Mirabito, L. Perries, S. Shchablo, K. Sordini, V and Torterotot, L. Touquet, G. Vander Donckt, M. Viret, S. and Lomidze, I Toriashvili, T. Tsamalaidze, Z. Mestvirishvili, A. Botta, V Feld, L. Klein, K. Lipinski, M. Meuser, D. Pauls, A. Rowert, N. Schulz, J. Teroerde, M. and Dodonova, A. Eliseev, D. Erdmann, M. Fackeldey, P. and Fischer, B. Hebbeker, T. Hoepfner, K. Ivone, F. and Mastrolorenzo, L. Merschmeyer, M. Meyer, A. Mocellin, G. and Mondal, S. Mukherjee, S. Noll, D. Novak, A. Pook, T. and Pozdnyakov, A. Rath, Y. Reithler, H. Roemer, J. Schmidt, A. Schuler, S. C. Sharma, A. Vigilante, L. Wiedenbeck, S. Zaleski, S. Borras, K. Kasem, A. Coubez, X. and Dziwok, C. Flugge, G. Ahmad, W. Haj Hlushchenko, O. and Kress, T. Nowack, A. Pistone, C. Pooth, O. Roy, D. and Stahl, A. Ziemons, T. Zotz, A. Petersen, H. Aarup and Martin, M. Aldaya Asmuss, P. Baxter, S. Bayatmakou, M. and Behnke, O. Martinez, A. Bermudez Bhattacharya, S. Bin Anuar, A. A. Brunner, D. Campbell, A. Cardini, A. Cheng, C. and Colombina, F. Rodriguez, S. Consuegra Silva, G. Correia and Danilov, V De Silva, M. Didukh, L. Eckerlin, G. and Eckstein, D. Banos, L. I. Estevez Filatov, O. Gallo, E. and Geiser, A. Giraldi, A. Grohsjean, A. Guthoff, M. Jafari, A. Jomhari, N. Z. Jung, H. Kasemann, M. Kaveh, H. and Kleinwort, C. Kogler, R. Krucker, D. Lange, W. Lidrych, J. Lipka, K. Lohmann, W. Mankel, R. Melzer-Pellmann, I-A and Morentin, M. Mendizabal Metwally, J. Meyer, A. B. Meyer, M. Mnich, J. Mussgiller, A. Otarid, Y. Adan, D. Perez and Pitzl, D. Raspereza, A. Lopes, B. Ribeiro Rubenach, J. and Saggio, A. Saibel, A. Savitskyi, M. Scham, M. and Scheurer, V Schnake, S. Schutze, P. Schwanenberger, C. and Shchedrolosiev, M. Ricardo, R. E. Sosa Stafford, D. Tonon, N. Van De Klundert, M. Walsh, R. Walter, D. Wang, Q. and Wen, Y. Wichmann, K. Wiens, L. Wissing, C. Wuchterl, S. and Bakhshiansohi, H. Aggleton, R. Albrecht, S. Bein, S. and Benato, L. Connor, P. De Leo, K. Eich, M. Feindt, F. and Frohlich, A. Garbers, C. Garutti, E. Gunnellini, P. and Hajheidari, M. Haller, J. Hinzmann, A. Kasieczka, G. and Klanner, R. Kramer, T. Kutzner, V Lange, J. Lange, T. and Lobanov, A. Malara, A. Nigamova, A. Rodriguez, K. J. Pena Rieger, M. Rieger, O. Schleper, P. Schroder, M. and Schwandt, J. Sonneveld, J. Stadie, H. Steinbruck, G. and Tews, A. Zoi, I Bechtel, J. Brommer, S. Burkart, M. and Butz, E. Caspart, R. Chwalek, T. De Boer, W. Dierlamm, A. Droll, A. El Morabit, K. Faltermann, N. Giffels, M. and Gosewisch, J. O. Gottmann, A. Hartmann, F. Heidecker, C. and Husemann, U. Keicher, P. Koppenhofer, R. Maier, S. and Metzler, M. Mitra, S. Muller, Th Neukum, M. Nurnberg, A. and Quast, G. Rabbertz, K. Rauser, J. Savoiu, D. and Schnepf, M. Seith, D. Shvetsov, I Simonis, H. J. Ulrich, R. Van der Linden, J. Von Cube, R. F. Wassmer, M. Weber, M. Wieland, S. Wolf, R. Wozniewski, S. Wunsch, S. and Anagnostou, G. Daskalakis, G. Geralis, T. Kyriakis, A. and Loukas, D. Stakia, A. Diamantopoulou, M. Karasavvas, D. and Karathanasis, G. Kontaxakis, P. Koraka, C. K. and Manousakis-Katsikakis, A. Panagiotou, A. Papavergou, I and Saoulidou, N. Theofilatos, K. Tziaferi, E. Vellidis, K. and Vourliotis, E. Sphicas, P. Bakas, G. Kousouris, K. and Papakrivopoulos, I Tsipolitis, G. Zacharopoulou, A. and Adamidis, K. Bestintzanos, I Evangelou, I Foudas, C. and Gianneios, P. Katsoulis, P. Kokkas, P. Manthos, N. and Papadopoulos, I Strologas, J. Csanad, M. Farkas, K. and Gadallah, M. M. A. Lokos, S. Major, P. Mandal, K. Mehta, A. Pasztor, G. Radl, A. J. Suranyi, O. Veres, I, G. and Trocsanyi, Z. L. Bartok, M. Bencze, G. Hajdu, C. and Horvath, D. Sikler, F. Veszpremi, V. Csorgo, T. Nemes, F. Czellar, S. Fasanella, D. Karancsi, J. Molnar, J. and Szillasi, Z. Teyssier, D. Raics, P. Ujvari, B. Novak, T. and Choudhury, S. Komaragiri, J. R. Kumar, D. Panwar, L. and Tiwari, P. C. Bahinipati, S. Kar, C. Mal, P. Mishra, T. and Bindhu, V. K. Muraleedharan Nair Nayak, A. Saha, P. Sur, N. Swain, S. K. Vats, D. Bansal, S. Beri, S. B. and Bhatnagar, V Chaudhary, G. Chauhan, S. Dhingra, N. and Gupta, R. Kaur, A. Kaur, M. Kaur, S. Kumari, P. and Meena, M. Sandeep, K. Singh, J. B. Virdi, A. K. Ahmed, A. Bhardwaj, A. Choudhary, B. C. Gola, M. Keshri, S. and Kumar, A. Naimuddin, M. Priyanka, P. Ranjan, K. Shah, A. and Bharti, M. Bhattacharya, R. Bhowmik, D. Dutta, S. and Gomber, B. Maity, M. Palit, P. Rout, P. K. Saha, G. and Sahu, B. Sarkar, S. Sharan, M. Singh, B. Thakur, S. and Behera, P. K. Behera, S. C. Kalbhor, P. Muhammad, A. and Pradhan, R. Pujahari, P. R. Sikdar, A. K. Dutta, D. Jha, V Kumar, V Mishra, D. K. Naskar, K. Netrakanti, P. K. and Pant, L. M. Shukla, P. Aziz, T. Dugad, S. Kumar, M. and Banerjee, S. Chudasama, R. Guchait, M. Karmakar, S. and Kumar, S. Majumder, G. Mazumdar, K. Alpana, K. Dube, S. and Kansal, B. Laha, A. Pandey, S. Rane, A. Rastogi, A. and Sharma, S. Khazaie, E. Zeinali, M. Chenarani, S. and Etesami, S. M. Khakzad, M. Najafabadi, M. Mohammadi and Grunewald, M. Abbrescia, M. Aly, R. Aruta, C. Colaleo, A. Creanza, D. De Filippis, N. De Palma, M. Di Florio, A. Di Pilato, A. Elmetenawee, W. Fiore, L. Gelmi, A. and Gul, M. Iaselli, G. Ince, M. Lezki, S. Maggi, G. and Maggi, M. Margjeka, I Mastrapasqua, V My, S. Nuzzo, S. and Pellecchia, A. Pompili, A. Pugliese, G. Ramos, D. and Ranieri, A. Selvaggi, G. Silvestris, L. Simone, F. M. and Venditti, R. Verwilligen, P. Abbiendi, G. Battilana, C. and Bonacorsi, D. Borgonovi, L. Brigliadori, L. Campanini, R. and Capiluppi, P. Castro, A. Cavallo, F. R. Cuffiani, M. and Dallavalle, G. M. Diotalevi, T. Fabbri, F. Fanfani, A. and Giacomelli, P. Giommi, L. Grandi, C. Guiducci, L. Lo Meo, S. Lunerti, L. Marcellini, S. Masetti, G. Navarria, F. L. Perrotta, A. Primavera, F. Rossi, A. M. Rovelli, T. Siroli, G. P. Albergo, S. Costa, S. Di Mattia, A. and Potenza, R. Tricomi, A. Tuve, C. Barbagli, G. Cassese, A. Ceccarelli, R. Ciulli, V Civinini, C. D'Alessandro, R. Focardi, E. Latino, G. Lenzi, P. Lizzo, M. and Meschini, M. Paoletti, S. Seidita, R. Sguazzoni, G. and Viliani, L. Benussi, L. Bianco, S. Piccolo, D. Bozzo, M. and Ferro, F. Mulargia, R. Robutti, E. Tosi, S. and Benaglia, A. Brivio, F. Cetorelli, F. De Guio, F. and Dinardo, M. E. Dini, P. Gennai, S. Ghezzi, A. Govoni, P. and Guzzi, L. Lucchini, M. T. Malberti, M. Malvezzi, S. and Massironi, A. Menasce, D. Moroni, L. Paganoni, M. and Pedrini, D. Ragazzi, S. Redaelli, N. de Fatis, T. Tabarelli and Valsecchi, D. Zuolo, D. Buontempo, S. Carnevali, F. and Cavallo, N. De Iorio, A. Fabozzi, F. Iorio, A. O. M. and Lista, L. Meola, S. Paolucci, P. Rossi, B. Sciacca, C. and Azzi, P. Bacchetta, N. Bisello, D. Bortignon, P. and Bragagnolo, A. Carlin, R. Checchia, P. Dorigo, T. and Dosselli, U. Gasparini, F. Gasparini, U. Hoh, S. Y. and Layer, L. Margoni, M. Meneguzzo, A. T. Pazzini, J. and Ronchese, P. Rossin, R. Simonetto, F. Strong, G. Tosi, M. Yarar, H. Zanetti, M. Zotto, P. Zucchetta, A. and Zumerle, G. Aime, C. Braghieri, A. Calzaferri, S. and Fiorina, D. Montagna, P. Ratti, S. P. Re, V Riccardi, C. and Salvini, P. Vai, I Vitulo, P. Fallavollita, F. and Asenov, P. Bilei, G. M. Ciangottini, D. Fano, L. and Mantovani, G. Mariani, V Menichelli, M. Moscatelli, F. and Piccinelli, A. Presilla, M. Rossi, A. Santocchia, A. and Spiga, D. Tedeschi, T. Magherini, M. Azzurri, P. and Bagliesi, G. Bertacchi, V Bianchini, L. Boccali, T. and Bossini, E. Castaldi, R. Ciocci, M. A. D'Amante, V and Dell'Orso, R. Di Domenico, M. R. Donato, S. Giassi, A. and Ligabue, F. Manca, E. Mandorli, G. Messineo, A. Palla, F. Parolia, S. Ramirez-Sanchez, G. Rizzi, A. Rolandi, G. and Chowdhury, S. Roy Scribano, A. Shafiei, N. Spagnolo, P. and Tenchini, R. Tonelli, G. Turini, N. Venturi, A. and Verdini, P. G. Barria, P. Campana, M. Cavallari, F. Del Re, D. Di Marco, E. Diemoz, M. Longo, E. Meridiani, P. and Organtini, G. Pandolfi, F. Paramatti, R. Quaranta, C. and Rahatlou, S. Rovelli, C. Santanastasio, F. Soffi, L. and Tramontano, R. Amapane, N. Arcidiacono, R. Argiro, S. and Arneodo, M. Bartosik, N. Bellan, R. Bellora, A. and Antequera, J. Berenguer Biino, C. Cartiglia, N. Cometti, S. and Costa, M. Covarelli, R. Demaria, N. Kiani, B. and Legger, F. Mariotti, C. Maselli, S. 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Herndon, M. Herve, A. and Hussain, U. Lanaro, A. Loeliger, A. Loveless, R. and Sreekala, J. Madhusudanan Mallampalli, A. Mohammadi, A. and Pinna, D. Savin, A. Shang, V Smith, W. H. Teague, D. and Trembath-Reichert, S. Vetens, W. CMS Collaboration
Subjects: High Energy Physics::Phenomenology, High Energy Physics::Experiment, Nuclear Experiment
Abstract: Inclusive and differential cross sections of single top quark production in association with a Z boson are measured in proton-proton collisions at a center-of-mass energy of 13 TeV with a data sample corresponding to an integrated luminosity of 138 fb(-1) recorded by the CMS experiment. Events are selected based on the presence of three leptons, electrons or muons, associated with leptonic Z boson and top quark decays. The measurement yields an inclusive cross section of 87.9(-7.3)(+7.5) (stat)(-6.0)(+7.3)(syst) fb for a dilepton invariant mass greater than 30 GeV, in agreement with standard model (SM) calculations and represents the most precise determination to date. The ratio between the cross sections for the top quark and the top antiquark production in association with a Z boson is measured as 2.37(-0.42)(+0.56)(stat)(-0.13)(+0.27) (syst). Differential measurements at parton and particle levels are performed for the first time. Several kinematic observables are considered to study the modeling of the process. Results are compared to theoretical predictions with different assumptions on the source of the initial-state b quark and found to be in agreement, within the uncertainties. Additionally, the spin asymmetry, which is sensitive to the top quark polarization, is determined from the differential distribution of the polarization angle at parton level to be 0.54 +/- 0.16 (stat)+/- 0.06 (syst), in agreement with SM predictions.
Published: 2022

6. Measurement and QCD analysis of double-differential inclusive jet cross sections in proton-proton collisions at root s=13 TeV

Author: Tumasyan, A. Adam, W. Andrejkovic, J. W. Bergauer, T. and Chatterjee, S. Damanakis, K. Dragicevic, M. Escalante Del Valle, A. Fruhwirth, R. Jeitler, M. Krammer, N. Lechner, L. Liko, D. Mikulec, I. Paulitsch, P. Pitters, F. M. and Schieck, J. Schofbeck, R. Schwarz, D. Templ, S. and Waltenberger, W. Wulz, C. -E. Chekhovsky, V. Litomin, A. and Makarenko, V. Darwish, M. R. De Wolf, E. A. Janssen, T. and Kello, T. Lelek, A. Rejeb Sfar, H. Van Mechelen, P. Van Putte, S. Van Remortel, N. Blekman, F. Bols, E. S. and D'Hondt, J. Delcourt, M. El Faham, H. Lowette, S. and Moortgat, S. Morton, A. Muller, D. Sahasransu, A. R. and Tavernier, S. Van Doninck, W. Beghin, D. Bilin, B. and Clerbaux, B. De Lentdecker, G. Favart, L. Grebenyuk, A. and Kalsi, A. K. Lee, K. Mahdavikhorrami, M. Makarenko, I. and Moureaux, L. Petre, L. Popov, A. Postiau, N. Starling, E. Thomas, L. Vanden Bemden, M. Vander Velde, C. and Vanlaer, P. Cornelis, T. Dobur, D. Knolle, J. Lambrecht, L. Mestdach, G. Niedziela, M. Roskas, C. Samalan, A. and Skovpen, K. Tytgat, M. Vermassen, B. Wezenbeek, L. and Benecke, A. Bethani, A. Bruno, G. Bury, F. Caputo, C. and David, P. Delaere, C. Donertas, I. S. Giammanco, A. and Jaffel, K. Jain, Sa. Lemaitre, V. Mondal, K. and Prisciandaro, J. Taliercio, A. Teklishyn, M. Tran, T. T. and Vischia, P. Wertz, S. Alves, G. A. Hensel, C. Moraes, A. and Alda Junior, W. L. Alves Gallo Pereira, M. Barroso Ferreira Filho, M. Brandao Malbouisson, H. Carvalho, W. Chinellato, J. Da Costa, E. M. Da Silveira, G. G. De Jesus Damiao, D. and Fonseca De Souza, S. Mora Herrera, C. Mota Amarilo, K. and Mundim, L. Nogima, H. Rebello Teles, P. Santoro, A. and Silva Do Amaral, S. M. Sznajder, A. Thiel, M. Torres Da Silva De Araujo, F. Vilela Pereira, A. Bernardes, C. A. and Calligaris, L. Fernandez Perez Tomei, T. R. Gregores, E. M. and Lemos, D. S. Mercadante, P. G. Novaes, S. F. Padula, Sandra S. Aleksandrov, A. Antchev, G. Hadjiiska, R. Iaydjiev, P. Misheva, M. Rodozov, M. Shopova, M. Sultanov, G. and Dimitrov, A. Ivanov, T. Litov, L. Pavlov, B. Petkov, P. and Petrov, A. Cheng, T. Javaid, T. Mittal, M. Yuan, L. and Ahmad, M. Bauer, G. Dozen, C. Hu, Z. Martins, J. and Wang, Y. Yi, K. Chapon, E. Chen, G. M. Chen, H. S. and Chen, M. Iemmi, F. Kapoor, A. Leggat, D. Liao, H. and Liu, Z. -A. Milosevic, V. Monti, F. Sharma, R. Tao, J. and Thomas-Wilsker, J. Wang, J. Zhang, H. Zhao, J. and Agapitos, A. An, Y. Ban, Y. Chen, C. Levin, A. Li, Q. Lyu, X. Mao, Y. Qian, S. J. Wang, D. Wang, Q. and Xiao, J. Lu, M. You, Z. Gao, X. Okawa, H. Zhang, Y. and Lin, Z. Xiao, M. Avila, C. Cabrera, A. Florez, C. and Fraga, J. Mejia Guisao, J. Ramirez, F. Ruiz Alvarez, J. D. Salazar Gonzalez, C. A. Giljanovic, D. Godinovic, N. and Lelas, D. Puljak, I. Antunovic, Z. Kovac, M. Sculac, T. and Brigljevic, V. Ferencek, D. Majumder, D. Roguljic, M. and Starodumov, A. Susa, T. Attikis, A. Christoforou, K. and Erodotou, E. Ioannou, A. Kole, G. Kolosova, M. and Konstantinou, S. Mousa, J. Nicolaou, C. Ptochos, F. and Razis, P. A. Rykaczewski, H. Saka, H. Finger, M. Finger, Jr., M. Kveton, A. Ayala, E. Carrera Jarrin, E. Assran, Y. Ellithi Kamel, A. Mahmoud, M. A. Mohammed, Y. and Bhowmik, S. Dewanjee, R. K. Ehataht, K. Kadastik, M. and Nandan, S. Nielsen, C. Pata, J. Raidal, M. Tani, L. and Veelken, C. Eerola, P. Forthomme, L. Kirschenmann, H. and Osterberg, K. Voutilainen, M. Bharthuar, S. Brucken, E. and Garcia, F. Havukainen, J. Kim, M. S. Kinnunen, R. and Lampen, T. Lassila-Perini, K. Lehti, S. Linden, T. and Lotti, M. Martikainen, L. Myllymaki, M. Ott, J. and Siikonen, H. Tuominen, E. Tuominiemi, J. Luukka, P. and Petrow, H. Tuuva, T. Amendola, C. Besancon, M. Couderc, F. Dejardin, M. Denegri, D. Faure, J. L. Ferri, F. and Ganjour, S. Gras, P. Hamel de Monchenault, G. Jarry, P. and Lenzi, B. Locci, E. Malcles, J. Rander, J. Rosowsky, A. and Sahin, M. O. Savoy-Navarro, A. Titov, M. Yu, G. B. and Ahuja, S. Beaudette, F. Bonanomi, M. 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Jones, M. Jung, A. W. and Karmarkar, S. Kondratyev, D. Liu, M. Negro, G. and Neumeister, N. Paspalaki, G. Piperov, S. Purohit, A. and Schulte, J. F. Stojanovic, M. Thieman, J. Wang, F. Xiao, R. Xie, W. Dolen, J. Parashar, N. Baty, A. Carnahan, T. Decaro, M. Dildick, S. Ecklund, K. M. Freed, S. and Gardner, P. Geurts, F. J. M. Kumar, A. Li, W. Padley, B. P. Redjimi, R. Shi, W. Stahl Leiton, A. G. Yang, S. and Zhang, L. Zhang, Y. Bodek, A. de Barbaro, P. Demina, R. and Dulemba, J. L. Fallon, C. Ferbel, T. Galanti, M. and Garcia-Bellido, A. Hindrichs, O. Khukhunaishvili, A. Ranken, E. Taus, R. Chiarito, B. Chou, J. P. Gandrakota, A. and Gershtein, Y. Halkiadakis, E. Hart, A. Heindl, M. and Karacheban, O. Laflotte, I. Lath, A. Montalvo, R. Nash, K. Osherson, M. Salur, S. Schnetzer, S. Somalwar, S. and Stone, R. Thayil, S. A. Thomas, S. Wang, H. Acharya, H. and Delannoy, A. G. Fiorendi, S. Spanier, S. Bouhali, O. and Dalchenko, M. Delgado, A. Eusebi, R. Gilmore, J. Huang, T. Kamon, T. Kim, H. Luo, S. Malhotra, S. Mueller, R. Overton, D. Rathjens, D. Safonov, A. Akchurin, N. and Damgov, J. Hegde, V. Kunori, S. Lamichhane, K. Lee, S. W. Mengke, T. Muthumuni, S. Peltola, T. Volobouev, I. and Wang, Z. Whitbeck, A. Appelt, E. Greene, S. Gurrola, A. Johns, W. Melo, A. Ni, H. Padeken, K. Romeo, F. and Sheldon, P. Tuo, S. Velkovska, J. Arenton, M. W. and Cox, B. Cummings, G. Hakala, J. Hirosky, R. Joyce, M. and Ledovskoy, A. Li, A. Neu, C. Perez Lara, C. E. and Tannenwald, B. White, S. Wolfe, E. Poudyal, N. Black, K. and Bose, T. Caillol, C. Dasu, S. De Bruyn, I. and Everaerts, P. Fienga, F. Galloni, C. He, H. Herndon, M. and Herve, A. Hussain, U. Lanaro, A. Loeliger, A. and Loveless, R. Madhusudanan Sreekala, J. Mallampalli, A. and Mohammadi, A. Pinna, D. Savin, A. Shang, V. Sharma, V. and Smith, W. H. Teague, D. Trembath-Reichert, S. Vetens, W. and CMS Collaboration
Subjects: High Energy Physics::Phenomenology, High Energy Physics::Experiment
Abstract: A measurement of the inclusive jet production in proton-proton collisions at the LHC at root s = 13TeV is presented. The double-differential cross sections are measured as a function of the jet transverse momentum p(T) and the absolute jet rapidity vertical bar y vertical bar. The anti- k(T) clustering algorithm is used with distance parameter of 0.4 (0.7) in a phase space region with jet p(T) from 97 GeV up to 3.1TeV and vertical bar y vertical bar < 2.0. Data collected with the CMS detector are used, corresponding to an integrated luminosity of 36.3 fb(-1) (33.5 fb(-1)). The measurement is used in a comprehensive QCD analysis at next-to-next-to-leading order, which results in significant improvement in the accuracy of the parton distributions in the proton. Simultaneously, the value of the strong coupling constant at the Z boson mass is extracted as alpha(S)(m(Z)) = 0.1170 +/- 0.0019. For the first time, these data are used in a standard model effective field theory analysis at next-to-leading order, where parton distributions and the QCD parameters are extracted simultaneously with imposed constraints on the Wilson coefficient c(1) of 4-quark contact interactions.
Published: 2022

7. Search for flavor-changing neutral current interactions of the top quark and the Higgs boson decaying to a bottom quark-antiquark pair at root s=13 TeV

Author: Tumasyan, A. Adam, W. Andrejkovic, J. W. Bergauer, T. and Chatterjee, S. Damanakis, K. Dragicevic, M. Escalante Del Valle, A. Fruhwirth, R. Jeitler, M. Krammer, N. Lechner, L. Liko, D. Mikulec, I. Paulitsch, P. Pitters, F. M. and Schieck, J. Schoefbeck, R. Schwarz, D. Templ, S. and Waltenberger, W. Wulz, C. -E. Chekhovsky, V. Litomin, A. and Makarenko, V. Darwish, M. R. De Wolf, E. A. Janssen, T. and Kello, T. Lelek, A. Rejeb Sfar, H. Van Mechelen, P. Van Putte, S. Van Remortel, N. Blekman, F. Bols, E. S. and D'Hondt, J. Delcourt, M. El Faham, H. Lowette, S. and Moortgat, S. Morton, A. Mueller, D. Sahasransu, A. R. and Tavernier, S. Van Doninck, W. Beghin, D. Bilin, B. and Clerbaux, B. De Lentdecker, G. Favart, L. Grebenyuk, A. and Kalsi, A. K. Lee, K. Mahdavikhorrami, M. Makarenko, I. and Moureaux, L. Petre, L. Popov, A. Postiau, N. Starling, E. Thomas, L. Vanden Bemden, M. Vander Velde, C. and Vanlaer, P. Cornelis, T. Dobur, D. Knolle, J. Lambrecht, L. Mestdach, G. Niedziela, M. Roskas, C. Samalan, A. and Skovpen, K. Tytgat, M. Vermassen, B. Wezenbeek, L. and Benecke, A. Bethani, A. Bruno, G. Bury, F. Caputo, C. and David, P. Delaere, C. Donertas, I. S. Giammanco, A. and Jaffel, K. Jain, Sa. Lemaitre, V. Mondal, K. and Prisciandaro, J. Taliercio, A. Teklishyn, M. Tran, T. T. and Vischia, P. Wertz, S. Alves, G. A. Hensel, C. Moraes, A. and Rebello Teles, P. Alda Junior, W. L. Alves Gallo Pereira, M. and Barroso Ferreira Filho, M. Brandao Malbouisson, H. Carvalho, W. Chinellato, J. Da Costa, E. M. Da Silveira, G. G. De Jesus Damiao, D. Fonseca De Souza, S. Mora Herrera, C. Mota Amarilo, K. Mundim, L. Nogima, H. Santoro, A. Silva Do Amaral, S. M. Sznajder, A. Thiel, M. Torres Da Silva De Araujo, F. Vilela Pereira, A. Bernardes, C. A. Calligaris, L. Fernandez Perez Tomei, T. R. Gregores, E. M. Lemos, D. S. and Mercadante, P. G. Novaes, S. F. Padula, Sandra S. and Aleksandrov, A. Antchev, G. Hadjiiska, R. Iaydjiev, P. and Misheva, M. Rodozov, M. Shopova, M. Sultanov, G. and Dimitrov, A. Ivanov, T. Litov, L. Pavlov, B. Petkov, P. and Petrov, A. Cheng, T. Javaid, T. Mittal, M. Yuan, L. and Ahmad, M. Bauer, G. Dozen, C. Hu, Z. Martins, J. and Wang, Y. Yi, K. Chapon, E. Chen, G. M. Chen, H. S. and Chen, M. Iemmi, F. Kapoor, A. Leggat, D. Liao, H. and Liu, Z. -A. Milosevic, V. Monti, F. Sharma, R. Tao, J. and Thomas-Wilsker, J. Wang, J. Zhang, H. Zhao, J. and Agapitos, A. An, Y. Ban, Y. Chen, C. Levin, A. Li, Q. Lyu, X. Mao, Y. Qian, S. J. Wang, D. Xiao, J. and Lu, M. You, Z. Gao, X. Okawa, H. Zhang, Y. Lin, Z. and Xiao, M. Avila, C. Cabrera, A. Florez, C. Fraga, J. and Mejia Guisao, J. Ramirez, F. Ruiz Alvarez, J. D. Salazar Gonzalez, C. A. Giljanovic, D. Godinovic, N. Lelas, D. and Puljak, I. Antunovic, Z. Kovac, M. Sculac, T. and Brigljevic, V. Ferencek, D. Majumder, D. Roguljic, M. and Starodumov, A. Susa, T. Attikis, A. Christoforou, K. and Erodotou, E. Ioannou, A. Kole, G. Kolosova, M. and Konstantinou, S. Mousa, J. 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Malhotra, S. Mueller, R. Overton, D. Rathjens, D. Safonov, A. Akchurin, N. Damgov, J. and Hegde, V. Kunori, S. Lamichhane, K. Lee, S. W. Mengke, T. Muthumuni, S. Peltola, T. Volobouev, I. Wang, Z. and Whitbeck, A. Appelt, E. Greene, S. Gurrola, A. Johns, W. and Melo, A. Ni, H. Padeken, K. Romeo, F. Sheldon, P. and Tuo, S. Velkovska, J. Arenton, M. W. Cox, B. and Cummings, G. Hakala, J. Hirosky, R. Joyce, M. Ledovskoy, A. Li, A. Neu, C. Perez Lara, C. E. Tannenwald, B. and White, S. Wolfe, E. Poudyal, N. Black, K. Bose, T. and Caillol, C. Dasu, S. De Bruyn, I. Everaerts, P. Fienga, F. Galloni, C. He, H. Herndon, M. Herve, A. Hussain, U. Lanaro, A. Loeliger, A. Loveless, R. Madhusudanan Sreekala, J. Mallampalli, A. Mohammadi, A. Pinna, D. and Savin, A. Shang, V. Sharma, V. Smith, W. H. Teague, D. and Trembath-Reichert, S. Vetens, W. CMS Collaboration
Subjects: High Energy Physics::Phenomenology, High Energy Physics::Experiment
Abstract: A search for flavor-changing neutral current interactions of the top quark (t) and the Higgs boson (H) is presented. The search is based on a data sample corresponding to an integrated luminosity of 137 fb(-1) recorded by the CMS experiment at the LHC in proton-proton collisions at root s = 13TeV. Events containing exactly one lepton (muon or electron) and at least three jets, among which at least two are identified as originating from the hadronization of a bottom quark, are analyzed. A set of deep neural networks is used for kinematic event reconstruction, while boosted decision trees distinguish the signal from the background events. No significant excess over the background predictions is observed, and upper limits on the signal production cross sections are extracted. These limits are interpreted in terms of top quark decay branching fractions (B) to the Higgs boson and an up (u) or a charm quark (c). Assuming one nonvanishing extra coupling at a time, the observed (expected) upper limits at 95% confidence level are B(t -> Hu) < 0.079 (0.11)% and B(t -> Hc) < 0.094 (0.086)%.
Published: 2022

8. Search for long-lived particles decaying to leptons with large impact parameter in proton-proton collisions at root s=13 TeV

Author: Tumasyan, A. Adam, W. Andrejkovic, J. W. Bergauer, T. and Chatterjee, S. Damanakis, K. Dragicevic, M. Del Valle, A. Escalante Fruhwirth, R. Jeitler, M. Krammer, N. Lechner, L. Liko, D. Mikulec, I Paulitsch, P. Pitters, F. M. and Schieck, J. Schofbeck, R. Schwarz, D. Templ, S. and Waltenberger, W. Wulz, C-E Chekhovsky, V Litomin, A. and Makarenko, V Darwish, M. R. De Wolf, E. A. Janssen, T. and Kello, T. Lelek, A. Sfar, H. Rejeb Van Mechelen, P. Van Putte, S. Van Remortel, N. Blekman, F. Bols, E. S. and D'Hondt, J. Delcourt, M. El Faham, H. Lowette, S. and Moortgat, S. Morton, A. Muller, D. Sahasransu, A. R. and Tavernier, S. Van Doninck, W. Beghin, D. Bilin, B. and Clerbaux, B. De Lentdecker, G. Favart, L. Grebenyuk, A. and Kalsi, A. K. Lee, K. Mahdavikhorrami, M. Makarenko, I and Moureaux, L. Petre, L. Popov, A. Postiau, N. Starling, E. Thomas, L. Vanden Bemden, M. Vander Velde, C. and Vanlaer, P. Cornelis, T. Dobur, D. Knolle, J. Lambrecht, L. Mestdach, G. Niedziela, M. Roskas, C. Samalan, A. and Skovpen, K. Tytgat, M. Vermassen, B. Wezenbeek, L. and Benecke, A. Bethani, A. Bruno, G. Bury, F. Caputo, C. and David, P. Delaere, C. Donertas, I. S. Giammanco, A. and Jaffel, K. Jain, Sa Lemaitre, V Mondal, K. Prisciandaro, J. Taliercio, A. Teklishyn, M. Tran, T. T. Vischia, P. and Wertz, S. Alves, G. A. Hensel, C. Moraes, A. Alda Junior, W. L. Gallo Pereira, M. Alves Ferreira Filho, M. Barroso and Malbouisson, H. Brandao Carvalho, W. Chinellato, J. Da Costa, E. M. Da Silveira, G. G. Damiao, D. De Jesus De Souza, S. Fonseca Herrera, C. Mora Amarilo, K. Mota Mundim, L. Nogima, H. Teles, P. Rebello Santoro, A. Silva Do Amaral, S. M. Sznajder, A. Thiel, M. Da Silva De Araujo, F. Torres Pereira, A. Vilela Bernardes, C. A. Calligaris, L. and Fernandez Perez Tomei, T. R. Gregores, E. M. Lemos, D. S. and Mercadante, P. G. Novaes, S. F. Padula, Sandra S. and Aleksandrov, A. Antchev, G. Hadjiiska, R. Iaydjiev, P. and Misheva, M. Rodozov, M. Shopova, M. Sultanov, G. and Dimitrov, A. Ivanov, T. Litov, L. Pavlov, B. Petkov, P. and Petrov, A. Cheng, T. Javaid, T. Mittal, M. Yuan, L. and Ahmad, M. Bauer, G. Dozen, C. Hu, Z. Martins, J. and Wang, Y. Yi, K. Chapon, E. Chen, G. M. Chen, H. S. and Chen, M. Iemmi, F. Kapoor, A. Leggat, D. Liao, H. and Liu, Z-A Milosevic, V Monti, F. Sharma, R. Tao, J. and Thomas-wilsker, J. Wang, J. Zhang, H. Zhao, J. Agapitos, A. An, Y. Ban, Y. Chen, C. Levin, A. Li, Q. Lyu, X. Mao, Y. Qian, S. J. Wang, D. Xiao, J. Lu, M. and You, Z. Gao, X. Okawa, H. Zhang, Y. Lin, Z. Xiao, M. and Avila, C. Cabrera, A. Florez, C. Fraga, J. Mejia Guisao, J. Ramirez, F. Ruiz Alvarez, J. D. Salazar Gonzalez, C. A. Giljanovic, D. Godinovic, N. Lelas, D. Puljak, I and Antunovic, Z. Kovac, M. Sculac, T. Brigljevic, V and Ferencek, D. Majumder, D. Roguljic, M. Starodumov, A. and Susa, T. Attikis, A. Christoforou, K. Erodotou, E. and Ioannou, A. Kole, G. Kolosova, M. Konstantinou, S. and Mousa, J. Nicolaou, C. Ptochos, F. Razis, P. 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A. and Bloom, K. Bryson, M. Claes, D. R. Fangmeier, C. Finco, L. Golf, F. Joo, C. Kravchenko, I Musich, M. Reed, I and Siado, J. E. Snow, G. R. Tabb, W. Yan, F. and Zecchinelli, A. G. Agarwal, G. Bandyopadhyay, H. Hay, L. and Iashvili, I. Kharchilava, A. McLean, C. Nguyen, D. and Pekkanen, J. Rappoccio, S. Williams, A. Alverson, G. and Barberis, E. Haddad, Y. Hortiangtham, A. Li, J. Madigan, G. Marzocchi, B. Morse, D. M. Nguyen, V Orimoto, T. and Parker, A. Skinnari, L. Tishelman-Charny, A. Wamorkar, T. and Wang, B. Wisecarver, A. Wood, D. Bueghly, J. Chen, Z. Gilbert, A. Gunter, T. Hahn, K. A. Liu, Y. Odell, N. Schmitt, M. H. Velasco, M. Band, R. Bucci, R. and Cremonesi, M. Das, A. Dev, N. Goldouzian, R. Hildreth, M. Anampa, K. Hurtado Jessop, C. Lannon, K. Lawrence, J. and Loukas, N. Lutton, D. Marinelli, N. Mcalister, I and McCauley, T. Mcgrady, C. Mohrman, K. Moore, C. Musienko, Y. Ruchti, R. Siddireddy, P. Townsend, A. Wayne, M. and Wightman, A. Zarucki, M. Zygala, L. Bylsma, B. Cardwell, B. Durkin, L. S. Francis, B. Hill, C. Ornelas, M. Nunez and Wei, K. Winer, B. L. Yates, B. R. Addesa, F. M. and Bonham, B. Das, P. Dezoort, G. Elmer, P. Frankenthal, A. and Greenberg, B. Haubrich, N. Higginbotham, S. and Kalogeropoulos, A. Kopp, G. Kwan, S. Lange, D. Marlow, D. Mei, K. Ojalvo, I Olsen, J. Stickland, D. Tully, C. Norberg, S. Bakshi, A. S. Barnes, V. E. Chawla, R. and Das, S. Gutay, L. Jones, M. Jung, A. W. Karmarkar, S. Kondratyev, D. Liu, M. Negro, G. Neumeister, N. and Paspalaki, G. Piperov, S. Purohit, A. Schulte, J. F. and Stojanovic, M. Thieman, J. Wang, F. Xiao, R. Xie, W. and Dolen, J. Parashar, N. Baty, A. Carnahan, T. Decaro, M. and Dildick, S. Ecklund, K. M. Freed, S. Gardner, P. and Geurts, F. J. M. Li, W. Padley, B. P. Redjimi, R. Shi, W. Leiton, A. G. Stahl Zhang, L. Bodek, A. de Barbaro, P. Demina, R. Dulemba, J. L. Fallon, C. Ferbel, T. and Galanti, M. Garcia-Bellido, A. Hindrichs, O. and Khukhunaishvili, A. Ranken, E. Taus, R. Chiarito, B. and Chou, J. P. Gandrakota, A. Gershtein, Y. Halkiadakis, E. and Hart, A. Heindl, M. Karacheban, O. Laflotte, I Lath, A. and Montalvo, R. Nash, K. Osherson, M. Salur, S. and Schnetzer, S. Somalwar, S. Stone, R. Thayil, S. A. and Thomas, S. Wang, H. Acharya, H. Delannoy, A. G. and Fiorendi, S. Spanier, S. Bouhali, O. Dalchenko, M. and Delgado, A. Eusebi, R. Gilmore, J. Huang, T. Kamon, T. and Luo, S. Malhotra, S. Mueller, R. Overton, D. and Rathjens, D. Safonov, A. Akchurin, N. Damgov, J. Hegde, V Kunori, S. Lamichhane, K. Mengke, T. Muthumuni, S. and Peltola, T. Volobouev, I Whitbeck, A. Appelt, E. Greene, S. Gurrola, A. Johns, W. Melo, A. Ni, H. Padeken, K. and Romeo, F. Sheldon, P. Tuo, S. Velkovska, J. Arenton, M. W. Cox, B. Cummings, G. Hakala, J. Hirosky, R. and Joyce, M. Ledovskoy, A. Li, A. Neu, C. Lara, C. E. Perez and Tannenwald, B. White, S. Wolfe, E. Poudyal, N. and Black, K. Bose, T. Caillol, C. Dasu, S. De Bruyn, I and Everaerts, P. Fienga, F. Galloni, C. He, H. Herndon, M. and Herve, A. Hussain, U. Lanaro, A. Loeliger, A. and Loveless, R. Sreekala, J. Madhusudanan Mallampalli, A. and Mohammadi, A. Pinna, D. Savin, A. Shang, V Smith, W. H. and Teague, D. Trembath-Reichert, S. Vetens, W. CMS Collaboration
Subjects: High Energy Physics::Experiment
Abstract: A search for new long-lived particles decaying to leptons using proton-proton collision data produced by the CERN LHC at root s = 13 TeV is presented. Events are selected with two leptons (an electron and a muon, two electrons, or two muons) that both have transverse impact parameter values between 0.01 and 10 cm and are not required to form a common vertex. Data used for the analysis were collected with the CMS detector in 2016, 2017, and 2018, and correspond to an integrated luminosity of 118 (113) fb(-1) in the ee channel (e mu and mu mu channels). The search is designed to be sensitive to a wide range of models with displaced e mu ee, and mu mu final states. The results constrain several well-motivated models involving new long-lived particles that decay to displaced leptons. For some areas of the available phase space, these are the most stringent constraints to date.
Published: 2022

9. Hybrid-gyrokinetic simulations of low-n toroidal Alfvén eigenmodes using gKPSP

Author: Y. W. Cho, J. M. Kwon, K. Kim, J. Kang, L. Jung, T. Rhee, and S. K. Kim
Subjects: Condensed Matter Physics
Abstract: We report a benchmark study of toroidal Alfvén eigenmode (TAE) simulation using the hybrid-gyrokinetic code GyroKinetic Plasma Simulation Program (gKPSP). A simulation capability for energetic particles based on the gyrokinetic δf method has been newly implemented in the gKPSP code. Benchmark simulations have been performed in both circular and realistic tokamak geometries. Good agreement has been found with previously reported results, demonstrating the new capability of the gKPSP code. We have investigated the effects of the distribution function on TAE stability by examining both isotropic and anisotropic slowing-down distributions of energetic particles. The slowing-down distribution produces a higher linear growth rate than a Maxwellian distribution, while a growth rate scan with the anisotropy shows an opposite trend. This can be attributed to competition between Landau damping and the linear drive, which are correlated with the fraction of resonant passing particles and their distribution in phase space.
Published: 2022
Full Text: View/download PDF

10. Search for new particles in events with energetic jets and large missing transverse momentum in proton-proton collisions at root s=13 TeV

Author: Tumasyan, A. Adam, W. Andrejkovic, J. W. Bergauer, T. and Chatterjee, S. Dragicevic, M. Del Valle, A. Escalante and Fruhwirth, R. Jeitler, M. Krammer, N. Lechner, L. Liko, D. Mikulec, I Paulitsch, P. Pitters, F. M. Schieck, J. and Schofbeck, R. Schwarz, D. Templ, S. Waltenberger, W. and Wulz, C-E Chekhovsky, V Litomin, A. Makarenko, V and Darwish, M. R. De Wolf, E. A. Janssen, T. Kello, T. and Lelek, A. Sfar, H. Rejeb Van Mechelen, P. Van Putte, S. and Van Remortel, N. Blekman, F. Bols, E. S. D'Hondt, J. and Delcourt, M. El Faham, H. Lowette, S. Moortgat, S. and Morton, A. Muller, D. Sahasransu, A. R. Tavernier, S. and Van Doninck, W. Van Mulders, P. Stylianou, N. Beghin, D. and Bilin, B. Clerbaux, B. De Lentdecker, G. Favart, L. and Grebenyuk, A. Kalsi, A. K. Lee, K. Mahdavikhorrami, M. and Makarenko, I Moureaux, L. Petre, L. Popov, A. Postiau, N. Starling, E. Thomas, L. Vanden Bemden, M. Vander Velde, C. Vanlaer, P. Wezenbeek, L. Gao, X. Cornelis, T. and Dobur, D. Knolle, J. Lambrecht, L. Mestdach, G. and Niedziela, M. Roskas, C. Samalan, A. Skovpen, K. Tytgat, M. Vermassen, B. Vit, M. Benecke, A. Bethani, A. and Bruno, G. Bury, F. Caputo, C. David, P. Delaere, C. and Donertas, I. S. Giammanco, A. Jaffel, K. Jain, Sa and Lemaitre, V Mondal, K. Prisciandaro, J. Taliercio, A. and Teklishyn, M. Tran, T. T. Vischia, P. Wertz, S. Alves, G. A. Hensel, C. Moraes, A. Alda Junior, W. L. Gallo Pereira, M. Alves Ferreira Filho, M. Barroso Malbouisson, H. Brandao Carvalho, W. Chinellato, J. Da Costa, E. M. Da Silveira, G. G. Damiao, D. De Jesus De Souza, S. Fonseca and Figueiredo, D. Matos Herrera, C. Mora Amarilo, K. Mota and Mundim, L. Nogima, H. Teles, P. Rebello Santoro, A. and Silva Do Amaral, S. M. Sznajder, A. Thiel, M. Da Silva De Araujo, F. Torres Pereira, A. Vilela Bernardes, C. A. and Calligaris, L. Fernandez Perez Tomei, T. R. Gregores, E. M. and Lemos, D. S. Mercadante, P. G. Novaes, S. F. Padula, Sandra S. Aleksandrov, A. Antchev, G. Hadjiiska, R. 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Grunendahl, S. Gutsche, O. Harris, R. M. Heller, R. Herwig, T. C. Hirschauer, J. Jayatilaka, B. Jindariani, S. Johnson, M. Joshi, U. Klijnsma, T. and Klima, B. Kwok, K. H. M. Lammel, S. Lincoln, D. Lipton, R. Liu, T. Madrid, C. Maeshima, K. Mantilla, C. and Mason, D. McBride, P. Merkel, P. Mrenna, S. Nahn, S. and Ngadiuba, J. O'Dell, V Papadimitriou, V Pedro, K. and Prokofyev, O. Ravera, F. Hall, A. Reinsvold Ristori, L. and Sexton-Kennedy, E. Smith, N. Soha, A. Spalding, W. J. and Spiegel, L. Stoynev, S. Strait, J. Taylor, L. Tkaczyk, S. Tran, V, N. Uplegger, L. Vaandering, E. W. Weber, H. A. Acosta, D. Avery, P. Bourilkov, D. Cadamuro, L. and Cherepanov, V Errico, F. Field, R. D. Guerrero, D. and Joshi, B. M. Kim, M. Koenig, E. Konigsberg, J. Korytov, A. Lo, K. H. Matchev, K. Menendez, N. Mitselmakher, G. and Madhu, A. Muthirakalayil Rawal, N. Rosenzweig, D. and Rosenzweig, S. Rotter, J. Shi, K. Sturdy, J. Yigitbasi, E. Zuo, X. Adams, T. Askew, A. Habibullah, R. and Hagopian, V Johnson, K. F. Khurana, R. Kolberg, T. and Martinez, G. Prosper, H. Schiber, C. Viazlo, O. Yohay, R. Zhang, J. Baarmand, M. M. Butalla, S. Elkafrawy, T. and Hohlmann, M. Verma, R. Kumar Noonan, D. Rahmani, M. and Yumiceva, F. Adams, M. R. Gonzalez, H. Becerril Cavanaugh, R. Chen, X. Dittmer, S. Evdokimov, O. Gerber, C. E. and Hangal, D. A. Hofman, D. J. Merrit, A. H. Mills, C. Oh, G. Roy, T. Rudrabhatla, S. Tonjes, M. B. Varelas, N. and Viinikainen, J. Wang, X. Wu, Z. Ye, Z. Alhusseini, M. and Dilsiz, K. Gandrajula, R. P. Koseyan, O. K. Merlo, J-P and Nachtman, J. Ogul, H. Onel, Y. Penzo, A. Snyder, C. and Tiras, E. Amram, O. Blumenfeld, B. Corcodilos, L. and Davis, J. Eminizer, M. Gritsan, V, A. Kyriacou, S. and Maksimovic, P. Roskes, J. Swartz, M. Vami, T. A. Abreu, A. Anguiano, J. Barrera, C. Baldenegro Baringer, P. and Bean, A. Bylinkin, A. Flowers, Z. Isidori, T. King, J. and Krintiras, G. Kropivnitskaya, A. Lazarovits, M. Lindsey, C. Marquez, J. Minafra, N. Murray, M. Nickel, M. and Rogan, C. Royon, C. Salvatico, R. Sanders, S. Schmitz, E. Smith, C. Takaki, J. D. Tapia Warner, Z. Williams, J. and Wilson, G. Duric, S. Ivanov, A. Kaadze, K. Kim, D. and Maravin, Y. Mitchell, T. Modak, A. Nam, K. Rebassoo, F. Wright, D. Adams, E. Baden, A. Baron, O. Belloni, A. Eno, S. C. Hadley, N. J. Jabeen, S. Kellogg, R. G. and Koeth, T. Mignerey, A. C. Nabili, S. Palmer, C. and Seidel, M. Skuja, A. Wang, L. Wong, K. Abercrombie, D. and Andreassi, G. Bi, R. Brandt, S. Busza, W. Cali, I. A. D'Alfonso, M. Eysermans, J. Freer, C. Ceballos, G. Gomez Goncharov, M. Harris, P. Hu, M. Klute, M. and Kovalskyi, D. Krupa, J. Lee, Y-J Mironov, C. Paus, C. and Rankin, D. Roland, C. Roland, G. Shi, Z. Stephans, G. S. F. Wang, Z. Wyslouch, B. Chatterjee, R. M. Evans, A. Hansen, P. Hiltbrand, J. Jain, Sh Krohn, M. and Kubota, Y. Mans, J. Revering, M. Rusack, R. Saradhy, R. and Schroeder, N. Strobbe, N. Wadud, M. A. Bloom, K. and Bryson, M. Claes, D. R. Fangmeier, C. Finco, L. Golf, F. and Joo, C. Kravchenko, I Musich, M. Reed, I Siado, J. E. Snow, G. R. Tabb, W. Yan, F. Zecchinelli, A. G. and Agarwal, G. Bandyopadhyay, H. Hay, L. Iashvili, I. and Kharchilava, A. McLean, C. Nguyen, D. Pekkanen, J. and Rappoccio, S. Williams, A. Alverson, G. Barberis, E. and Haddad, Y. Hortiangtham, A. Li, J. Madigan, G. and Marzocchi, B. Morse, D. M. Nguyen, V Orimoto, T. Parker, A. Skinnari, L. Tishelman-Charny, A. Wamorkar, T. Wang, B. Wisecarver, A. Wood, D. Bueghly, J. Chen, Z. and Gilbert, A. Gunter, T. Hahn, K. A. Liu, Y. Odell, N. and Schmitt, M. H. Velasco, M. Band, R. Bucci, R. Das, A. and Dev, N. Goldouzian, R. Hildreth, M. Anampa, K. Hurtado and Jessop, C. Lannon, K. Lawrence, J. Loukas, N. and Lutton, D. Marinelli, N. Mcalister, I McCauley, T. and Mcgrady, C. Mohrman, K. Ruchti, R. Siddireddy, P. and Townsend, A. Wayne, M. Wightman, A. Zarucki, M. Zygala, L. Bylsma, B. Cardwell, B. Durkin, L. S. Francis, B. and Hill, C. Ornelas, M. Nunez Wei, K. Winer, B. L. Yates, B. R. Addesa, F. M. Bonham, B. Das, P. Dezoort, G. and Elmer, P. Frankenthal, A. Greenberg, B. Haubrich, N. and Higginbotham, S. Kalogeropoulos, A. Kopp, G. Kwan, S. and Lange, D. Marlow, D. Mei, K. Ojalvo, I Olsen, J. and Stickland, D. Tully, C. Norberg, S. Bakshi, A. S. and Barnes, V. E. Chawla, R. Das, S. Gutay, L. Jones, M. and Jung, A. W. Karmarkar, S. Kondratyev, D. Liu, M. Negro, G. Neumeister, N. Paspalaki, G. Piperov, S. Purohit, A. and Schulte, J. F. Stojanovic, M. Thieman, J. Wang, F. and Xiao, R. Xie, W. Dolen, J. Parashar, N. Baty, A. and Decaro, M. Dildick, S. Ecklund, K. M. Freed, S. Gardner, P. Geurts, F. J. M. Li, W. Padley, B. P. Redjimi, R. and Shi, W. Leiton, A. G. Stahl Zhang, L. Bodek, A. de Barbaro, P. Demina, R. Dulemba, J. L. Fallon, C. Ferbel, T. Galanti, M. Garcia-Bellido, A. Hindrichs, O. and Khukhunaishvili, A. Ranken, E. Taus, R. Chiarito, B. and Chou, J. P. Gandrakota, A. Gershtein, Y. Halkiadakis, E. and Hart, A. Heindl, M. Karacheban, O. Laflotte, I Lath, A. and Montalvo, R. Nash, K. Osherson, M. Salur, S. and Schnetzer, S. Somalwar, S. Stone, R. Thayil, S. A. and Thomas, S. Wang, H. Acharya, H. Delannoy, A. G. and Fiorendi, S. Spanier, S. Bouhali, O. Dalchenko, M. and Delgado, A. Eusebi, R. Gilmore, J. Huang, T. Kamon, T. and Luo, S. Malhotra, S. Mueller, R. Overton, D. and Rathjens, D. Safonov, A. Akchurin, N. Damgov, J. Hegde, V Kunori, S. Lamichhane, K. Mengke, T. Muthumuni, S. and Peltola, T. Volobouev, I Whitbeck, A. Appelt, E. Greene, S. Gurrola, A. Johns, W. Melo, A. Ni, H. Padeken, K. and Romeo, F. Sheldon, P. Tuo, S. Velkovska, J. Arenton, M. W. Cox, B. Cummings, G. Hakala, J. Hirosky, R. and Joyce, M. Ledovskoy, A. Li, A. Neu, C. Lara, C. E. Perez and Tannenwald, B. White, S. Wolfe, E. Poudyal, N. and Black, K. Bose, T. Caillol, C. Dasu, S. De Bruyn, I and Everaerts, P. Fienga, F. Galloni, C. He, H. Herndon, M. and Herve, A. Hussain, U. Lanaro, A. Loeliger, A. and Loveless, R. Sreekala, J. Madhusudanan Mallampalli, A. and Mohammadi, A. Pinna, D. Savin, A. Shang, V Smith, W. H. and Teague, D. Trembath-Reichert, S. Vetens, W. CMS Collaboration
Subjects: High Energy Physics::Phenomenology, High Energy Physics::Experiment
Abstract: A search is presented for new particles produced at the LHC in proton-proton collisions at root s = 13 TeV, using events with energetic jets and large missing transverse momentum. The analysis is based on a data sample corresponding to an integrated luminosity of 101 fb(-1), collected in 2017-2018 with the CMS detector. Machine learning techniques are used to define separate categories for events with narrow jets from initial-state radiation and events with large-radius jets consistent with a hadronic decay of a W or Z boson. A statistical combination is made with an earlier search based on a data sample of 36 fb(-1), collected in 2016. No significant excess of events is observed with respect to the standard model background expectation determined from control samples in data. The results are interpreted in terms of limits on the branching fraction of an invisible decay of the Higgs boson, as well as constraints on simplified models of dark matter, on first-generation scalar leptoquarks decaying to quarks and neutrinos, and on models with large extra dimensions. Several of the new limits, specifically for spin-1 dark matter mediators, pseudoscalar mediators, colored mediators, and leptoquarks, are the most restrictive to date.
Published: 2021

11. Extended bounce-kinetic model for trapped electron mode turbulence

Author: Y. J. Kim, J. M. Kwon, Lei Qi, and T. S. Hahm
Subjects: Physics::Plasma Physics, Condensed Matter Physics
Abstract: The bounce-kinetic model based on the modern nonlinear bounce-kinetic theory [Fong and Hahm, Phys. Plasmas 6, 188 (1999)] has been developed and used for simulations previously. This work reports on an extension of the bounce-kinetic model including more accurate treatment of barely trapped particles and its implementation in the Gyro-Kinetic Plasma Simulation Program gyrokinetic code [Kwon et al., Comp. Phys. Commun. 215, 81 (2017)]. This leads to more accurate gyrokinetic simulations of the collisionless trapped electron mode at low magnetic shear.
Published: 2022
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12. On hybrid scenarios in KSTAR

Author: J. W. Juhn, W.C. Lee, S.W. Yoon, Boseong Kim, Won-Ha Ko, M.S. Park, Y. H. Lee, Chanyoung Lee, Jayhyun Kim, Jisung Kang, S. K. Kim, Gyungjin Choi, Kstar Team, Young-Mu Jeon, S. Yi, J. Citrin, SeongMoo Yang, J. M. Kwon, Hyun-Seok Kim, Yong-Su Na, C.S. Byun, Gunsu Yun, and Minho Woo
Subjects: Superconducting tokamak, Physics, Nuclear and High Energy Physics, Thesaurus (information retrieval), Pedestal, KSTAR, Nuclear engineering, 0103 physical sciences, Sawtooth wave, 010306 general physics, Condensed Matter Physics, 01 natural sciences, 010305 fluids & plasmas
Abstract: We report the status of hybrid scenario experiments in Korea Superconducting Tokamak Advanced Research (KSTAR). The hybrid scenario is defined as stationary discharges with B N >= 2.4 and H_89 >= 2.0 at q_95 < 6.5 without or with very mild sawtooth activities in KSTAR. It is being developed towards reactor-relevant conditions. High performance of B N
Published: 2020
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13. A reduced model for edge localized mode control by supersonic molecular beam injection and pellet injection

Author: Patrick Diamond, J. M. Kwon, and Tongnyeol Rhee
Subjects: Physics, Pedestal, Bistability, Pellet, Supersonic speed, Mechanics, Condensed Matter Physics, Edge-localized mode, Molecular beam, Instability, Ballooning
Abstract: We develop a diffusive, bistable, tri-unstable cellular automata (CA) model to study the dynamics of H-mode pedestal with edge localized modes (ELMs) and their control by supersonic molecular beam injection (SMBI) and pellet injection (PI). It is shown that the new CA model can reproduce the key features of H-mode pedestals with various types of ELM, including Type-I ELM. SMBI and PI are modeled as additional grain injections into pedestal with varying degrees of injected materials and profiles. It is found that H-mode pedestal responds to SMBI differently depending on the baseline fueling. If the baseline fueling is large enough to allow Type-I ELM, SMBI enhances large transport avalanches caused by ballooning instabilities. These avalanches prevent the total pedestal current from reaching the boundary for peeling instability. On the other hand, if the baseline fueling is low to avoid Type-I ELM, SMBI enhances small scale avalanches, which prevent the pedestal from growing to profiles globally vulnerable to ballooning instabilities. These imply that SMBI can mitigate different types of ELM by converting them to more benign types. From CA modeling of pellet injection, it is shown that Type-I ELM can be triggered by pellet injection with sufficient strength and depth. Scanning the frequency of pellet injection, it is found that a maximum efficiency of pellet pacing is achieved when the injection frequency is approximately ten times the natural frequency of Type-I ELM.
Published: 2020
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14. Observation of non-local effects in ion transport channel in J-TEXT plasmas

Author: SeulChan Hong, Zhou Hao, X. L. Zhang, W. Yan, J. M. Kwon, Z.F. Cheng, K.J. Zhao, Y. Liang, Zhoujun Yang, SeongMoo Yang, Yuejiang Shi, Zhipeng Chen, Y.B. Dong, Zhongyong Chen, Cai Qinxue, Lu Wang, Peng Shi, X. M. Pan, Partick H. Diamond, Yonghua Ding, Yong-Su Na, Zhongbing Shi, and Jie Wen
Subjects: Physics, Nuclear and High Energy Physics, FOS: Physical sciences, Ion temperature, Plasma, Condensed Matter Physics, Non local, 01 natural sciences, Physics - Plasma Physics, 010305 fluids & plasmas, Ion, Plasma Physics (physics.plasm-ph), Physics::Plasma Physics, Phase (matter), 0103 physical sciences, Atomic physics, 010306 general physics, Ion transporter
Abstract: Author(s): Shi, Y; Yang, Z; Chen, Z; Cheng, Z; Zhang, X; Yan, W; Wen, J; Cai, Q; Zhao, K; Hong, S; Kwon, J; Diamond, PH; Shi, P; Zhou, H; Pan, X; Chen, Z; Yang, S; Dong, Y; Wang, L; Ding, Y; Liang, Y; Shi, Z; Na, YS | Abstract: In cold pulse experiments in J-TEXT, the ion transport shows similar non-local response as the electron transport channel. Very fast ion temperature decreases are observed in the edge, while the ion temperature in the core promptly begin to rise after the injection of cold pulse. Moreover, the cutoff density is also found for the ion non-local effect. The experimental observed density fluctuation in a high frequency ranging from 500 kHz to 2 MHz is obviously reduced in the whole plasma region during non-local transport phase.
Published: 2020
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15. The effect of Epstein–Barr virus status on clinical outcome in Hodgkin’s lymphoma

Author: Young-Hyeh Ko, Soon Il Lee, Keon Ha Kim, Yeon Hee Park, Hong Hoe Koo, Baek-Yeol Ryoo, J. M. Kwon, Wook Sung Kim, Jihoon Kang, and Sung Sook Lee
Subjects: Adult, Male, Oncology, Epstein-Barr Virus Infections, Herpesvirus 4, Human, medicine.medical_specialty, Pathology, medicine.disease_cause, Disease-Free Survival, Virus, hemic and lymphatic diseases, Internal medicine, medicine, Humans, Epstein–Barr virus infection, Survival analysis, Retrospective Studies, Hematology, business.industry, virus diseases, General Medicine, medicine.disease, Hodgkin's lymphoma, Hodgkin Disease, Survival Analysis, Epstein–Barr virus, Lymphoma, Treatment Outcome, Immunohistochemistry, Female, business
Abstract: The association of Epstein-Barr virus (EBV) with Hodgkin's lymphoma (HL) has been investigated over the last few years. The impact of EBV on clinical outcome is still controversial, however. In this study, we investigated the effect of EBV status on clinical outcome of HL patients. Between January 1986 and September 2004, fifty-six patients, diagnosed as having HL, were included in the analysis. Clinical data were reviewed retrospectively from the patients' records. Tissues from 56 patients were analyzed for the presence of EBV using the in situ hybridization (ISH) for EBV-encoded RNA (EBER) and immunohistochemistry for latent membrane protein (LMP)1. EBV infection was identified in 41.1% of cases by EBER ISH, 26.8% by LMP1 expression, and 26.8% by LMP1 and EBER ISH. EBER-positive HL were significantly more frequent in mixed cellularity (MC) subtype (P=0.014) and advanced stage (P=0.034). There was a trend toward shorter overall survival in EBER-positive patients without statistical significance (P=0.238). LMP1 expression also correlated with MC subtype (P=0.006) and advanced stage (P=0.007), although it did not significantly influence the survival outcome. In subgroup analysis, both EBER and LMP1 positivities were associated with longer progression-free survival in patients with age25 years old (P=0.045). Reverse trends were shown in patientsor =25 years old. In this study, we demonstrated that the impact of tumor EBV status on prognosis may be age dependent and young patients with latent EBV infection have favorable prognosis.
Published: 2006
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16. Observation of multi-channel non-local transport in J-TEXT plasmas

Author: Zhiping Chen, Yong-Su Na, Yuejiang Shi, J. M. Kwon, K.J. Zhao, Yonghua Ding, Peng Shi, Zhoujun Yang, Zhou Hao, Chi Zhang (张弛), X. M. Pan, W. Yan, SeongMoo Yang, Lu Wang, Y.B. Dong, Y. Liang, Zhongyong Chen, Z.F. Cheng, Hogun Jhang, SangHee Hahn, Patrick Diamond, and Da Li
Subjects: Physics, Nuclear and High Energy Physics, Toroid, Turbulence, Plasma, Condensed Matter Physics, Rotation, 01 natural sciences, Molecular physics, 010305 fluids & plasmas, Pulse (physics), Core (optical fiber), Acceleration, 0103 physical sciences, Electron temperature, 010306 general physics
Abstract: In cold pulse experiments in J-TEXT, not only are rapid electron temperature increases in the core observed, but also steep rises in the inner density are found. Moreover, some evidence of acceleration of the core toroidal rotation is also observed during the non-local transport process of electron temperature. These new findings of cold pulse experiments in J-TEXT suggest that turbulence spreading is a possible mechanism for the non-local transport dynamics.
Published: 2018
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17. Observation of electron driven quasi-coherent modes and their connection with core intrinsic rotation in KSTAR ECH and ohmic L-mode plasmas

Author: N. C. LuhmannJr., Kang Wook Kim, Hyeon K. Park, S. H. Ko, G. S. Yun, J. Leem, J. M. Kwon, Kstar Team, Wai Ming Lee, and Yoon Soo Park
Subjects: Physics, Toroid, Cyclotron, Electron, Plasma, Collisionality, Condensed Matter Physics, 01 natural sciences, 010305 fluids & plasmas, law.invention, Physics::Plasma Physics, law, KSTAR, Physics::Space Physics, 0103 physical sciences, Electron temperature, Atomic physics, 010306 general physics, Ohmic contact
Abstract: Quasi-coherent (QC) modes, known as a type of the trapped electron mode (TEM) turbulence, have been measured in the outboard core region of low-density electron cyclotron resonant heating (ECH) injected and ohmically heated L-mode plasmas on the Korea Superconducting Tokamak Advanced Research (KSTAR) device. It appears that QC modes of 20–60 kHz occur or strengthen with an increase of the electron temperature to ion temperature ratio, but weaken or are fully suppressed by increased density/collisionality. Toroidal rotation shear, which is strongly related to the density/collisionality, also seems to stabilize the QC modes. Linear gyrokinetic simulations indicate that TEM is the most unstable mode at low densities where the QC modes are observed for both the ECH and ohmic plasmas. At high densities where the QC modes are suppressed, the most unstable mode is the ion temperature gradient (ITG) mode for the ECH plasmas but still TEM for the ohmic plasmas. In the ECH plasmas, it is found that the direction of...
Published: 2018
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18. Corrigendum: Multiscale interaction between a large scale magnetic island and small scale turbulence (2017 Nucl. Fusion 57 126058)

Author: W. Lee, Jaehyun Lee, K. D. Lee, Neville C. Luhmann, B. H. Park, Gunsu Yun, M. Kim, W. H. Ko, Yoon Soo Park, M. J. Choi, H.K. Park, J. H. Lee, J. Kim, J. M. Kwon, Yong-Su Na, and Y. In
Subjects: Nuclear and High Energy Physics, Fusion, Scale (ratio), Turbulence, Statistical physics, Condensed Matter Physics, Geology
Published: 2018
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19. Formation of the internal transport barrier in KSTAR

Author: H. H. Lee, Jin-Hyuk Chung, Jik-Soo Kim, J.H. Lee, Won-Ha Ko, S.W. Yoon, S. Yi, Young-Mu Jeon, Sang-hee Hahn, Minjun Choi, K.D. Lee, J. M. Kwon, Jinseok Ko, and H.S. Kim
Subjects: Nuclear and High Energy Physics, Tokamak, Materials science, Nuclear engineering, Plasma, Fusion power, Transport barrier, Condensed Matter Physics, 01 natural sciences, 010305 fluids & plasmas, law.invention, Superconducting tokamak, law, KSTAR, 0103 physical sciences, Electron temperature, Current (fluid), 010306 general physics
Abstract: One of key objectives of tokamak experiments is the exploration of enhanced confinement regimes, and the access of the internal transport barrier (ITB) formation is dealt with an important physics issue in the most of major tokamaks. Also, the advanced tokamak scenario with ITB is expected to lead to a continuous reactor with high fusion power density. From that point of view, the formation of the ITB in KSTAR which is designed for long pulse operation capability is very important although its heating and current drive systems are not fully equipped yet. We have therefore assumed that an early injection of the full NBI power (~5.5 MW) during the current ramp-up would give a chance to form an internal barrier if the plasma could stay in the L-mode. To avoid the H-mode transition, we have produced inboard limited plasmas with detaching from the both upper and lower divertors. Using this approach, an ITB formation during L-mode has been observed which shows improved core confinement. Ion and electron temperature profiles show the barrier clearly in the temperature, and it was sustained for about 7 s in the dedicated experiment. This is the first stationary ITB observed in a full superconducting tokamak. This operation scenario with the ITB could be an alternative way to achieve a high performance regime in KSTAR, and the length of the ITB discharge could be extended even longer. In this paper, we present the formation of the ITB using measured and simulated characteristic profiles.
Published: 2017
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20. A comprehensive study on rotation reversal in KSTAR: experimental observations and modelling

Author: Kstar Team, Yuejiang Shi, Won-Ha Ko, J.A. Lee, Hogun Jhang, Sang-Gu Lee, C. Angioni, SeongMoo Yang, D.H. Na, Yann Camenen, Yong-Su Na, J. M. Kwon, T.S. Hahm, KSTAR Team, Max-Planck-Institut für Plasmaphysik [Garching] (IPP), Physique des interactions ioniques et moléculaires (PIIM), and Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)
Subjects: rotation reversal, Nuclear and High Energy Physics, KSTAR, Ohmic plasma, intrinsic rotation, Electron, Collisionality, Rotation, 01 natural sciences, 010305 fluids & plasmas, Momentum diffusion, Nuclear magnetic resonance, anchor point, [PHYS.PHYS.PHYS-PLASM-PH]Physics [physics]/Physics [physics]/Plasma Physics [physics.plasm-ph], Physics::Plasma Physics, 0103 physical sciences, 010306 general physics, Shearing (physics), Physics, Toroid, Mechanics, Plasma, Condensed Matter Physics, momentum transport, gradient region
Abstract: International audience; Dedicated experiments have been performed in KSTAR Ohmic plasmas to investigate the detailed physics of the rotation reversal phenomena. Here we adapt the more general definition of rotation reversal, a large change of the intrinsic toroidal rotation gradient produced by minor changes in the control parameters (Camenen et al 2017 Plasma Phys. Control. Fusion 59 034001), which is commonly observed in KSTAR regardless of the operating conditions. The two main phenomenological features of the rotation reversal are the normalized toroidal rotation gradient (u') change in the gradient region and the existence of an anchor point. For the KSTAR Ohmic plasma database including the experiment results up to the 2016 experimental campaign, both features were investigated. First, the observations show that the locations of the gradient and the anchor point region are dependent on q(95). Second, a strong dependence of u' on nu(eff) is clearly observed in the gradient region, whereas the dependence on R/L-Ti, R/L-Te, and R/L-ne is unclear considering the usual variation of the normalized gradient length in KSTAR. The experimental observations were compared against several theoretical models. The rotation reversal might not occur due to the transition of the dominant turbulence from the trapped electron mode to the ion temperature gradient mode or the neoclassical equilibrium effect in KSTAR. Instead, it seems that the profile shearing effects associated with a finite ballooning tilting well reproduce the experimental observations of both the gradient region and the anchor point; the difference seems to be related to the magnetic shear and the q value. Further analysis implies that the increase of u' in the gradient region with the increase of the collisionality would occur when the reduction of the momentum diffusivity is comparatively larger than the reduction of the residual stress. It is supported by the perturbative analysis of the experiments and the nonlinear gyrokinetic simulations. The absence of the sign change of u' even when a much lower collisionality is produced by additional electron cyclotron heating brings further experimental support to this interpretation.
Published: 2017
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21. Intrinsic rotation reversal, non-local transport, and turbulence transition in KSTAR L-mode plasmas

Author: Yuejiang Shi, S. W. Yoon, J. H. Jeong, W. C. Lee, J.A. Lee, Y. S. Bae, M. Joung, S. G. Lee, J. Leem, SeongMoo Yang, Jaehyun Lee, Won-Ha Ko, Minjun Choi, K. D. Lee, Patrick Diamond, J. M. Kwon, Jung-Woo Yoo, Katsumi Ida, D.H. Na, Sang-hee Hahn, Yong-Su Na, and S. H. Ko
Subjects: Physics, Nuclear and High Energy Physics, Tokamak, Turbulence, Plasma, Electron, Collisionality, Condensed Matter Physics, 01 natural sciences, Electron cyclotron resonance, 010305 fluids & plasmas, law.invention, Ion, Physics::Plasma Physics, law, Physics::Space Physics, 0103 physical sciences, Diamagnetism, Atomic physics, 010306 general physics
Abstract: Experiments of electron cyclotron resonance heating (ECH) power scan in KSTAR tokamak clearly demonstrate that both the cutoff density for non-local heat transport (NLT) and the threshold density for intrinsic rotation reversal can be determined by the collisionality. We demonstrate that NLT can be affected by ECH, and the intrinsic rotation direction follows the changes of NLT. The cutoff density of NLT and threshold density for rotation reversal can be significantly increased by ECH. The poloidal flow of turbulence in core plasma is in the electron and the ion diamagnetic direction in ECH plasmas and high density OH plasma, respectively. The auto-power spectra of density fluctuation are almost the same in the outer region for both ECH and OH plasmas. On the other hand, the divergence in density fluctuation spectra at high frequency range between OH and ECH plasma is clearly observed in core region. The features of linear confinement and saturated confinement also appeared in ECH plasma, which is similar to the linear ohmic confinement (LOC) mode and saturate ohmic confinement (SOC) mode. All these observations in macroscopic parameters and micro fluctuations suggest a possible link between the macro phenomena and the structural changes in turbulence mode.
Published: 2017
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22. Characteristics of toroidal rotation and ion temperature pedestals between ELM bursts in KSTAR H-mode plasmas

Author: S. S. Kim, Hogun Jhang, W. H. Ko, S. H. Ko, L. Terzolo, and J. M. Kwon
Subjects: Physics, Momentum (technical analysis), Toroid, Physics::Instrumentation and Detectors, Plasma, Condensed Matter Physics, Rotation, 01 natural sciences, Neutral beam injection, 010305 fluids & plasmas, Pedestal, Physics::Plasma Physics, KSTAR, 0103 physical sciences, Torque, Atomic physics, 010306 general physics
Abstract: Steep pedestal profiles of ion temperature (Ti) and toroidal rotation ( Vϕ) are routinely observed in neutral beam injection (NBI)-heated KSTAR H-mode plasmas [W. H. Ko et al., Nucl. Fusion 55, 083013 (2015)]. In this work, we report a result of detailed analysis of pedestal characteristics. By analyzing a set of data with different experimental conditions, we show that Ti and Vϕ pedestals are coupled to each other and correlation between them becomes stronger when NBI-torque is lower. This suggests the existence of intrinsic toroidal torque in the pedestal. Based on a 1D transport analysis, we find that the prevalence of residual micro-turbulences is necessary to explain momentum transport in the pedestal. The estimated strength of intrinsic torque is shown to be comparable to that from a 2.7 MW NBI source. Finally, we show that non-diffusive momentum flux is indispensable to explain momentum transport in the pedestal, and a residual stress model fits the observed momentum flux reasonably.
Published: 2016
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23. Physics of Intrinsic Rotation in Flux-Driven ITG Turbulence

Author: S Ku, P H Dimond, G Dif-Pradalier, J M Kwon, Y Sarazin, T S Hahm, X Garbet, C S Chang, G Latu, E S Yoon, Ph Ghendrih, S Yi, A Strugarek, and W Solomon
Published: 2012
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24. On the mechanism for edge localized mode mitigation by supersonic molecular beam injection

Author: W. W. Xiao, J. M. Kwon, Tongnyeol Rhee, and Patrick Diamond
Subjects: Physics, Pedestal, Scale (ratio), Physics::Plasma Physics, Plasma instability, Nanotechnology, Supersonic speed, Mechanics, Condensed Matter Physics, Edge-localized mode, Molecular beam, Cellular automaton
Abstract: We construct a diffusive, bi-stable cellular automata model to elucidate the physical mechanisms underlying observed edge localized mode (ELM) mitigation by supersonic molecular beam injection (SMBI). The extended cellular automata model reproduces key qualitative features of ELM mitigation experiments, most significantly the increase in frequency of grain ejection events (ELMs), and the decrease in the number of grains ejected by these transport events. The basic mechanism of mitigation is the triggering of small scale pedestal avalanches by additional grain injection directly into the H-mode pedestal. The small scale avalanches prevent the gradient from building-up to marginality throughout the pedestal, thus avoiding large scale transport events which span the full extent of that region. We explore different grain injection parameters to find an optimal SMBI scenario. We show that shallow SMBI deposition is sufficient for ELM mitigation.
Published: 2012
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25. Toroidal rotation profile structure in KSTAR L-mode plasmas with mixed heating by NBI and ECH

Author: Y. S. Bae, K. W. Hill, Katsumi Ida, L. Terzolo, K. D. Lee, Gunsu Yun, Sang-hee Hahn, Won-Ha Ko, SH Seo, J. M. Kwon, S. H. Ko, Patrick Diamond, Manfred Bitter, Yuejiang Shi, S. W. Yoon, J. H. Jeong, and S. Yi
Subjects: Nuclear and High Energy Physics, Toroid, Materials science, Mathematics::General Topology, Electron, Plasma, Condensed Matter Physics, 01 natural sciences, Neutral beam injection, Electron cyclotron resonance, 010305 fluids & plasmas, Ion, Physics::Plasma Physics, KSTAR, 0103 physical sciences, Electron temperature, Atomic physics, 010306 general physics
Abstract: The structure of the toroidal rotation profile with mixed heating by neutral beam injection (NBI) and electron cyclotron resonance heating (ECH) has been investigated in KSTAR L-mode plasmas. ECH with varying resonance layer positions was used for heating a mix control. The experimental results show that ECH causes a counter-current rotation increment both for off-axis and on-axis ECH heating. For L-mode plasmas, off-axis ECH produces larger counter-current rotation than on-axis ECH. Analysis of ion heat and momentum transport for the ECH L-mode plasmas shows that the electron temperature gradient is the main reason for the degradation of ion heat confinement and also the main driving force for the non-diffusive momentum flux. As a possible mechanism for the counter-current intrinsic torque with ECH, the transition of the turbulence mode from ion temperature gradient (ITG) to the trapped electron mode (TEM) with the resulting sign change of turbulence driven residual stress is suggested. A linear gyro-kinetic analysis shows the ITG → TEM transition occurs in a localized region during ECH injection, and the trend of TEM excitation is consistent with the observed macroscopic trend of the toroidal rotation.
Published: 2015
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26. Ion temperature and toroidal velocity edge transport barriers in KSTAR

Author: Katsumi Ida, S. H. Ko, J. H. Lee, J. G. Kwak, Won-Ha Ko, Patrick Diamond, S. W. Yoon, Young-Mu Jeon, and J. M. Kwon
Subjects: Nuclear and High Energy Physics, Toroid, Materials science, Physics::Instrumentation and Detectors, business.industry, Plasma, Condensed Matter Physics, Rotation, Neutral beam injection, Hysteresis, Pedestal, Optics, Physics::Plasma Physics, KSTAR, Atomic physics, Edge-localized mode, business
Abstract: © 2015 IAEA, Vienna Printed in the UK. The structure and evolution of the ion temperature (Ti) and toroidal rotation (V-) profile have been investigated in neutral beam injection (NBI)-heated KSTAR H-mode plasmas, both without and with resonant magnetic pertubations (RMPs). A clear disparity between the width of the ∇Vφpedestal and that of the ∇Ti-pedestal was observed. Also, it was found that there exists a close correlation and weak relative hysteresis between the pedestal ∇Vφand ∇Ti during both L →H and H →L transitions. During the L →H transition, the Vφpedestal is observed to form ahead of the Ti-pedestal, and build inward from the separatrix. Linear gyrokinetic stability analysis of these KSTAR profiles was performed. The results indicate that parallel velocity shear is a relevant drive for pedestal turbulence and transport. This was largely ignored in previous studies of the pedestal micro-stability. Pedestal ion temperature and rotation profiles were also measured during edge localized mode (ELM) suppression experiments on KSTAR using an n = 1 RMPs. It was found that the top values of the ion temperature and toroidal rotation pedestal drop with RMPs when ELMs are suppressed.
Published: 2015
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27. High-dose chemotherapy with autologous stem cell transplantation in extranodal NK/T-cell lymphoma: a retrospective comparison with non-transplantation cases

Author: H J Kim, S M Bang, J Lee, H C Kwon, C Suh, J H Lee, B Y Ryoo, Y H Park, J M Kwon, S Y Oh, H R Lee, K Kim, C W Jung, K Park, and W S Kim
Subjects: Subset Analysis, Oncology, Adult, Male, medicine.medical_specialty, Time Factors, Adolescent, medicine.medical_treatment, Lymphoma, T-Cell, Transplantation, Autologous, Autologous stem-cell transplantation, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, T-cell lymphoma, Humans, Survivors, Survival analysis, Retrospective Studies, Transplantation, Chemotherapy, Hematology, business.industry, Middle Aged, medicine.disease, Combined Modality Therapy, Survival Analysis, Surgery, Lymphoma, Treatment Outcome, Female, business, Stem Cell Transplantation
Abstract: To determine the role of high-dose chemotherapy and autologous stem cell transplantation (HDC/ASCT) in extranodal NK/T-cell lymphoma patients, we conducted a retrospective analysis. In our previous study, we searched for patients who had received HDC/ASCT and identified 16 eligible patients and compared the treatment outcome with historical control group (n=246). Nine patients received HDC/ASCT in the first (CR1) or second complete remission (CR2), while seven patients received HDC/ASCT as salvage. Twelve of 16 patients achieved or maintained CR after HDC/ASCT. Among the 12 patients, five patients relapsed. Estimated 2-year overall survival (OS) and relapse-free survival (RFS) rates were 71.3+/-12.4% and 25.8+/-14.3%, respectively. There was a tendency of better survival in patients who received HDC/ASCT as compared to those who did not (P=0.091). In subset analysis, patients who underwent HDC/ASCT at CR (P=0.049) and patients with stage III or IV (P=0.001) had a favorable outcome. Patients with NKIPI 3,4 or EUNKTL, who underwent HDC/ASCT had more prolonged survival without statistical significance (P=0.055 and 0.056). In conclusion, HDC/ASCT may be considered as a treatment option for patients with extranodal NK/T-cell lymphoma, especially those in CR, with advanced disease (stage III/IV or EUNKTL) and high NKIPI scores.
Published: 2006

28. Physical Regimes Accessible to the Ignitor Experiment and Relevant Theoretical Developments

Author: B. Coppi 1), M.C. Firpo 1), L.E. Sugiyama 1), A. Airoldi 2), F. Bombarda 3), G. Cenacchi 3), P. Detragiache 3), C. Ferro, W. Horton 4), H.V. Wong 4), J. Van Dam 4), H.L. Berk 4), B. Hu 4), F. Porcelli 5), Duk-In Choi 6), and J.-M. Kwon 6)
Subjects: ___
Abstract: ___
Published: 2002

29. APTWG: The 4th Asia-Pacific Transport Working Group Meeting

Author: Yusuke Kosuga, J. M. Kwon, Yasushi Todo, Shigeru Inagaki, M. Leconte, Katsumi Ida, and Won-Ha Ko
Subjects: Radiation transport, Nuclear and High Energy Physics, Asia pacific, Plasma instability, Regional science, Transport barrier, Condensed Matter Physics, Particle transport
Abstract: This conference report summarizes the contributions to, and discussions at, the 4th Asia-Pacific Transport Working Group Meeting held at Kyushu University, Japan, during 10–13 June 2014. The topics of the meeting were organized under five main headings: turbulence suppression and transport barrier formation, effect of magnetic topology on MHD activity and transport, non-diffusive contribution of momentum and particle transport, non-local transport and turbulence spreading and coupling, energetic particles and instability. The Young Researchers' Forum which was held in this meeting is also described in this report.
Published: 2014
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30. The 3rd Asia–Pacific Transport Working Group (APTWG) Meeting

Author: Katsumi Ida, Hogun Jhang, J. M. Kwon, Patrick Diamond, Naoki Tamura, Yusuke Kosuga, and M. Leconte
Subjects: Physics, Nuclear physics, Nuclear and High Energy Physics, Momentum (technical analysis), Asia pacific, Group (periodic table), Fusion plasma, Transport barrier, Condensed Matter Physics, Working group
Abstract: This conference report summarizes the contributions to and discussions at the 3rd Asia–Pacific Transport Working Group (APTWG) meeting held in Jeju-island, Korea, on 21–24 May 2013. The main objective of the meeting is to develop a predictive understanding of transport mechanisms in magnetically confined fusion plasmas. In an effort to accomplish this objective, four technical working groups were organized under the headings: (1) transport barrier formation and confinement enhancement, (2) 3D effects and Magnetohydrodynamic–turbulence interaction, (3) momentum transport and non-locality and (4) particle/impurity transport and energetic particles.
Published: 2014
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31. The candidate gene approach

Author: J M, Kwon and A M, Goate
Subjects: alcohol dehydrogenases, Polymorphism, Genetic, Chromosome Mapping, Genetic Variation, Articles, aldehyde dehydrogenases, genetic theory of AODU (AOD [alcohol or other drug] use, abuse, and dependence), nucleotides, Pedigree, Alcoholism, Disease Models, Animal, Mice, Quantitative Trait, Heritable, quantitative trait locus, genetic linkage, Mutation, Animals, Humans, genetic polymorphism, Genetic Predisposition to Disease, apolipoproteins, Alzheimer’s disease
Abstract: Alcoholism has a significant genetic basis, and identifying genes that confer a susceptibility to alcoholism will aid clinicians in preventing and effectively treating the disease. One commonly used technique to identify genetic risk factors for complex disorders such as alcoholism is the candidate gene approach, which directly tests the effects of genetic variants of a potentially contributing gene in an association study. These studies, which may include members of an affected family or unrelated cases and controls, can be performed relatively quickly and inexpensively and may allow identification of genes with small effects. However, the candidate gene approach is limited by how much is known of the biology of the disease being investigated. As researchers identify potential candidate genes using animal studies or linking them to DNA regions implicated through other analyses, the candidate gene approach will continue to be commonly used.
Published: 2001

32. A genome screen of maximum number of drinks as an alcoholism phenotype

Author: N L, Saccone, J M, Kwon, J, Corbett, A, Goate, N, Rochberg, H J, Edenberg, T, Foroud, T K, Li, H, Begleiter, T, Reich, and J P, Rice
Subjects: Family Health, Male, Alcoholism, Random Allocation, Phenotype, Alcohol Drinking, Genotype, Genome, Human, Chromosome Mapping, Humans, Female, Lod Score, Microsatellite Repeats
Abstract: The Collaborative Study on the Genetics of Alcoholism (COGA) is a multicenter research program to detect and map susceptibility genes for alcohol dependence and related phenotypes. The measure M of "maximum number of drinks consumed in a 24-hour period" is closely related to alcoholism diagnosis in this dataset and provides a quantitative measure to grade nonalcoholic individuals. Twin studies have shown log(M) to have a heritability of approximately 50%. Genome screens for this trait were performed in two distinct genotyped samples (wave 1 and wave 2), and in the combined sample. MAPMAKER/SIBS was used to carry out Haseman-Elston based regression analyses. On chromosome 4, an unweighted all-pairs multipoint LOD of 2.2 was obtained between D4S2407 and D4S1628 in wave 1; in wave 2, the region flanked by D4S2404 and D4S2407 gave a LOD of 1.5. In the combined sample, the maximal LOD was 3.5 very close to D4S2407. This evidence for linkage is in the region of the alcohol dehydrogenase gene cluster on chromosome 4. These findings on chromosome 4 are consistent with a prior report from COGA in which strictly defined nonalcoholic subjects in wave 1 were analyzed. The present analysis on log(M) allows more individuals to be included and thus is potentially more powerful.
Published: 2000

33. Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

Author: Jennifer Adamson, Joanne Norton, Nicholas K. Hayward, Tony Tannenberg, F. Owen, Henry Houlden, David M. A. Mann, Patrizia Rizzu, John Hardy, Sumitra Chakraverty, Andrew Grover, J. C. van Swieten, Petra Nowotny, Marijke Joosse, E. De Graaff, Dennis W. Dickson, David Craufurd, M. Stevens, J. Van Baren, Julie S. Snowden, Corinne Lendon, Hans Basun, Peter Heutink, J. M. Kwon, Sarah Lincoln, Adrian M. Isaacs, Lars Lannfelt, Timothy Lynch, Ben A. Oostra, L. A. Reed, E. Wauters, Lien Kuei Che, John Q. Trojanowski, Peter R. Dodd, David Neary, Athena Andreadis, J. Hackett, Peter R. Schofield, Stuart Pickering-Brown, Frances Dark, M. Hillebrand, Peter Davies, Matt Baker, Susanne Froelich, Stanley Fahn, John C. Morris, John B.J. Kwok, Ronald C. Petersen, Mike Hutton, M. Neystat, Alison Goate, Neurology, Clinical Genetics, and Epidemiology
Subjects: Male, RNA Splicing, Tau protein, DNA Mutational Analysis, tau Proteins, Biology, Frontotemporal dementia and parkinsonism linked to chromosome 17, Exon, medicine, Missense mutation, Humans, Genetics, Multidisciplinary, Frontotemporal lobar degeneration, Charged multivesicular body protein 2B, Exons, medicine.disease, Pedigree, Alternative Splicing, Mutation, Nerve Degeneration, biology.protein, Pick's disease, Dementia, Female, Tauopathy, Chromosomes, Human, Pair 17
Abstract: Thirteen families have been described with an autosomal dominantly inherited dementia named frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17)(1-9), historically termed Pick's disease(10). Most FTDP-17 cases show neuronal and/or glial inclusions that stain positively with antibodies raised against the microtubule-associated protein Tau, although the Tau pathology varies considerably in both its quantity (or severity) and characteristics(1-8,12). Previous studies have mapped the FTDP-17 locus to a 2-centimorgan region on chromosome 17q21.11; the tau gene also lies within this region. We have now sequenced tau in FTDP-17 families and identified three missense mutations (G272V, P301L and R406W) and three mutations in the 5' splice site of exon in. The splice-site mutations all destabilize a potential stem-loop structure which is probably involved in regulating the alternative splicing of exon10 (ref. 13). This causes more frequent usage of the 5' splice site and an increased proportion of tan transcripts that include exon 10. The increase in exon 10(+) messenger RNA will increase the proportion of Tau containing four microtubule-binding repeats, which is consistent with the neuropathology described in several families with FTDP-17 (refs 12, 14).
Published: 1998

34. Genetic analysis of kifafa, a complex familial seizure disorder

Author: R J, Neuman, J M, Kwon, L, Jilek-Aall, H T, Rwiza, J P, Rice, and P J, Goodfellow
Subjects: Adult, Male, Epilepsy, Adolescent, Infant, Pedigree, Age Distribution, Child, Preschool, Prevalence, Humans, Female, Age of Onset, Child, Research Article
Abstract: Kifafa is the Swahili name for an epileptic seizure disorder, first reported in the early 1960s, that is prevalent in the Wapogoro tribe of the Mahenge region of Tanzania in eastern Africa. A 1990 epidemiological survey of seizure disorders in this region reported a prevalence in the range of 19/1,000-36/1,000, with a mean age at onset of 11.6 years; 80% of those affected had onset prior to 20 years of age. A team of investigators returned to Tanzania in 1992 and collected data on > 1,600 relatives of 26 probands in 20 kifafa families. We have undertaken a genetic analysis of these data in order to detect the presence of familial clustering and whether such aggregation could be attributed to genetic factors. Of the 127 affected individuals in these pedigrees, 23 are first-degree relatives (parent, full sibling, or offspring) of the 26 probands; 20 are second-degree relatives (half-sibling, grandparent, uncle, or aunt). When corrected for age, the risk to first-degree relatives is .15; the risk to second-degree relatives is .063. These risks are significantly higher than would be expected if there were no familial clustering. Segregation analysis, using PAP (rev.4.0), was undertaken to clarify the mode of inheritance. Among the Mendelian single-locus models, an additive model was favored over either a dominant, recessive, or codominant model. The single-locus model could be rejected when compared with the mixed Mendelian model (inclusion of a polygenic background), although the major-gene component tends to be recessive.(ABSTRACT TRUNCATED AT 250 WORDS)
Published: 1995

35. Effect of secondary convective cells on turbulence intensity profiles, flow generation, and transport

Author: J. M. Kwon, Patrick Diamond, T. Rhee, and S. Yi
Subjects: Convection, Physics, Turbulence, K-epsilon turbulence model, Reynolds number, K-omega turbulence model, Mechanics, Reynolds stress, Condensed Matter Physics, Physics::Fluid Dynamics, symbols.namesake, Classical mechanics, Eddy, Physics::Space Physics, Turbulence kinetic energy, symbols
Abstract: This paper reports the results of gyrokinetic simulation studies of ion temperature gradient driven turbulence which investigate the role of non-resonant modes in turbulence spreading, turbulence regulation, and self-generated plasma rotation. Non-resonant modes, which are those without a rational surface within the simulation domain, are identified as nonlinearly driven, radially extended convective cells. Even though the amplitudes of such convective cells are much smaller than that of the resonant, localized turbulence eddies, we find from bicoherence analysis that the mode-mode interactions in the presence of such convective cells increase the efficiency of turbulence spreading associated with nonlocality phenomena. Artificial suppression of the convective cells shows that turbulence spreading is reduced, and that the turbulence intensity profile is more localized. The more localized turbulence intensity profile produces stronger Reynolds stress and E × B shear flows, which in turn results in more effective turbulence self-regulation. This suggests that models without non-resonant modes may significantly underestimate turbulent fluctuation levels and transport. © 2012 American Institute of Physics.
Published: 2012
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36. Commingling and segregation analyses: comparison of results from a simulation study of a quantitative trait

Author: J M, Kwon, M, Boehnke, T L, Burns, and P P, Moll
Subjects: Male, Chi-Square Distribution, Genetic Techniques, Models, Genetic, Evaluation Studies as Topic, Data Interpretation, Statistical, Humans, Regression Analysis, Female, Pedigree
Abstract: Commingling analysis is commonly used to provide preliminary evidence for a single genetic locus with a major effect on the quantitative trait of interest. In this paper, the effectiveness of commingling analysis as a screening technique to identify samples for segregation analysis is assessed by applying both commingling and segregation analyses to samples of simulated pedigree data in which a major locus is segregating in the presence of polygenes and an individual-specific environmental effect. Under the circumstances simulated here, there is evidence for a single locus from segregation analysis but not from commingling analysis in at least 20% of the samples. No more than 2% of the samples provided evidence for commingling but not for segregation of a single locus. Comparisons of the samples that give evidence for both commingling and segregation, evidence for one but not the other, and no evidence for either show that evidence for commingling depends on the distributional characteristics of the trait in the sample, while support for the single locus from segregation analysis depends on both the distributional characteristics as well as the transmission of the rarer allele from parents to offspring. Since lack of commingling does not rule out the existence of a single locus in the realistic situations considered here, commingling analysis has limited usefulness as a screening technique for the presence for a single locus. In contrast, evidence for commingling does suggest the possibility that a single locus has a major effect on the trait and commingling analysis can provide guidance in the choice of initial parameter estimates for segregation analysis.
Published: 1990

37. Nonlinear gyrokinetic analysis of linear ohmic confinement to saturated ohmic confinement transition.

Author: L. Qi, J.-M. Kwon, H. Jhang, T.S. Hahm, and M. Leconte
Subjects: *NONLINEAR analysis, *ENERGY dissipation, *ION temperature, *ENERGY level transitions, *TURBULENCE
Abstract: This work presents a nonlinear gyrokinetic analysis, which addresses one of the perennial conundrums in ohmically heated fusion plasmas. The widely observed linear ohmic confinement (LOC) to saturated ohmic confinement (SOC) transition of the energy confinement time with increasing density is successfully reproduced from nonlinear gyrokinetic simulations for the first time. Suppression of trapped electron turbulence by collisional detrapping due to increasing density is found to be responsible for the transition. The microturbulence transition from trapped electron modes to ion temperature gradient modes is found to coincide, but is not a necessary condition for the LOC–SOC transition. Damping of nonlinearly generated zonal flow by increasing collisionality with density can be responsible for the energy confinement degradation in the SOC regime. [ABSTRACT FROM AUTHOR]
Published: 2020
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38. Contribution of APOE promoter polymorphisms to Alzheimer's disease risk

Author: C. Ellis, R. Sulkava, P. J. Tienari, M. Haltia, M. Ezquerra-Trabalon, R. C. Petersen, Marie-Christine Chartier-Harlin, John C. Morris, J. M. Harris, A. M. Cumming, F. Valdivieso, D M Mann, Bernard Frigard, J. M. Kwon, Florence Pasquier, Jordi Pérez-Tur, L. Araria-Goumidi, Jean-Charles Lambert, A. Frank, M. J. Artiga, D. St. Clair, Alison Goate, F. Wavrant-DeVrièze, J. C. Wang, John Hardy, I. Sastre, P. Amouyel, D. Hernandez, L. Myllykangas, María J. Bullido, and C. L. Lendon
Subjects: Male, Apolipoprotein E, Linkage disequilibrium, Genotype, Apolipoprotein E4, Population, Locus (genetics), Biology, Polymorphism, Single Nucleotide, Linkage Disequilibrium, Cohort Studies, Apolipoproteins E, Alzheimer Disease, Risk Factors, medicine, Humans, Genetic Predisposition to Disease, Allele, Promoter Regions, Genetic, education, Aged, Aged, 80 and over, Genetics, education.field_of_study, Odds ratio, medicine.disease, Female, lipids (amino acids, peptides, and proteins), Neurology (clinical), Alzheimer's disease
Abstract: Objective: To determine whether the effects of APOE promoter polymorphisms on AD are independent of the APOE -e4 allele. Background: Recently, the −491 A→T and −219 G→T polymorphisms located in the APOE promoter have been suggested to be risk factors for AD. However, the effects of these polymorphisms have not always been reproduced in case-control studies, possibly because of the strong linkage disequilibrium existing at this locus or the characteristics of the populations studied. Methods: Data collection was performed from six independent samples (1,732 patients with AD and 1,926 control subjects) genotyped for APOE exon 4 and the two APOE promoter polymorphisms. The risks associated with the APOE polymorphisms for developing AD were estimated using logistic regression procedures and calculation of odds ratios with 95% CI adjusted by age, sex, and collection center. Independence of the APOE promoter polymorphisms was tested by stratification for APOE -e4 and tertile design was used for age stratification. Results: The independence of the −491 AA genotype was observed in the whole sample whereas the independence of the −219 TT genotype was observed only in the oldest population. Conclusion: The −491 and −219 APOE promoter polymorphisms incur risk for AD in addition to risk associated with the APOE -e4 allele, with age accentuating the effect of the −219 TT genotype. Because these polymorphisms appear to influence apoE levels, these results suggest that APOE expression is an important determinant of AD pathogenesis.

39. Corrigendum: Multiscale interaction between a large scale magnetic island and small scale turbulence (2017 Nucl. Fusion 57 126058).

Author: M.J. Choi, J. Kim, J.-M. Kwon, H.K. Park, Y. In, W. Lee, K.D. Lee, G.S. Yun, J. Lee, M. Kim, W.-H. Ko, J.H. Lee, Y.S. Park, Y.-S. Na, N. C. Luhmann Jr, and B.H. Park
Subjects: MAGNETICS, TURBULENCE
Published: 2018
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40. Multiscale interaction between a large scale magnetic island and small scale turbulence.

Author: M.J. Choi, J. Kim, J.-M. Kwon, H.K. Park, Y. In, W. Lee, K.D. Lee, G.S. Yun, J. Lee, M. Kim, W.-H. Ko, J.H. Lee, Y.S. Park, Y.-S. Na, N.C. Luhmann Jr, and B.H. Park
Subjects: MAGNETIC flux, PLASMA turbulence, MOLECULAR interactions, ELECTRON temperature measurement, PLASMA flow
Abstract: Multiscale interaction between the magnetic island and turbulence has been demonstrated through simultaneous two-dimensional measurements of turbulence and temperature and flow profiles. The magnetic island and turbulence can mutually interact via coupling between the electron temperature (Te) gradient, the Te turbulence, and the poloidal flow. The Te gradient altered by the magnetic island steepens outside and flattens inside the island. The Te turbulence can appear in increased Te gradient regions. The combined effects of the Te gradient and the poloidal flow shear determines the two-dimensional distribution of the Te turbulence. When the poloidal vortex flow forms, it can maintain the steepest Te gradient and the magnetic island acts more like an electron heat transport barrier. Interestingly, when the Te gradient, the Te turbulence, and the vortex flow shear increase beyond critical levels, the magnetic island turns into a fast electron heat transport channel, which directly leads to the minor disruption. [ABSTRACT FROM AUTHOR]
Published: 2017
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